Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| antibacterial, modulatory activity of antibiotics and toxicity from rhinella jimi (stevaux, 2002) (anura: bufonidae) glandular secretions. | the increase in microorganisms with resistance to medications has caused a strong preoccupation within the medical and scientific community. animal toxins studies, such as parotoid glandular secretions from amphibians, possesses a great potential in the development of drugs, such as antimicrobials, as these possess bioactive compounds. it was evaluated rhinella jimi (stevaux, 2002) glandular secretions against standard and multi-resistant bacterial strains; the effect of secretions combined with ... | 2017 | 28577494 |
| dendrimer-functionalized electrospun nanofibres as dual-action water treatment membranes. | this work reports the preparation of composite electrospun membranes combining antimicrobial action with the capacity of retaining low-molecular weight non-polar pollutants. the membranes were electrospun blends of polyvinyl alcohol (pva) and poly(acrylic acid) (paa) stabilized using heat curing. the membranes were functionalized by grafting amino-terminated poly(amidoamine) (pamam) g3 dendrimers. the antimicrobial effect was assessed using strains of escherichia coli and staphylococcus aureus b ... | 2017 | 28577408 |
| electrospinning of ag nanowires/polyvinyl alcohol hybrid nanofibers for their antibacterial properties. | in order to developing a sort of flexible fibrous mats with outstanding and durable antibacterial activates, silver nanowires incorporated into polyvinyl alcohol (pva) nanofibers were fabricated by electrospun method. uniform ag nanowires (nws) were synthesized through a template-free method of solvothermal combined with polyol process, and then, they were dispersed in pva solution. at last, ag nws embedded in pva (ag nws/pva) hybrid nanofibrous films were gained by electrospun of the mixed solu ... | 2017 | 28576041 |
| ag-bamoo4: er(3+)/yb(3+) photocatalyst for antibacterial application. | silver loaded and er(3+)/yb(3+) doped bamoo4 octahedron microcrystals were fabricated by microwave hydrothermal process. the synthesized samples were characterized by x-ray diffraction (xrd), field emission scanning electron microscopy (fesem), energy dispersive x-ray spectroscopy (eds), and ultraviolet-visible diffuse reflection spectroscopy (uv-vis drs). the antibacterial application of samples were investigated by visible light irradiation and disk-diffusion method towards representative gram ... | 2017 | 28575953 |
| fresh preservation of alfalfa sprouts and mushroom slices by soaking with thymol and resveratrol solutions. | the preservation of fresh produce served as salads through soaking with solutions containing naturally occurring phenolic ingredients is of merit. for a primary assay, thymol and resveratrol at 0-500 ppm were prepared and used to inhibit growth and survival of escherichia coli and staphylococcus aureus. thymol and resveratrol exhibited potent inhibitory activities against the growth of both bacteria. for s. aureus, cells treated with thymol at 250 ppm or resveratrol at 500 ppm, the durations to ... | 2017 | 28572968 |
| absolute noninvasive measurement of co<sub>2</sub> mole fraction emitted by e. coli and s. aureus using calibration-free 2f wms applied to a 2004 nm vcsel. | we report the first demonstration, to the best of our knowledge, of accurate real-time noninvasive measurement of the absolute cumulative mole fraction of metabolic carbon dioxide emitted by escherichia coli and staphylococcus aureus over a period of several hours of their life cycles using a recently developed calibration-free wavelength modulation spectroscopy technique. a 1 mw vertical-cavity surface-emitting laser is used to interrogate a single rotational vibrational absorption line of carb ... | 2017 | 28569866 |
| prevention of bacterial colonization on catheters by a one-step coating process involving an antibiofouling polymer in water. | as reports of multidrug resistant pathogens have increased, patients with implanted medical catheters increasingly need alternative solutions to antibiotic treatments. as most catheter-related infections are directly associated with biofilm formation on the catheter surface, which, once formed, is difficult to eliminate, a promising approach to biofilm prevention involves inhibiting the initial adhesion of bacteria to the surface. in this study, we report an amphiphilic, antifouling polymer, pol ... | 2017 | 28569502 |
| role of biofilm in cerebrospinal fluid shunt infections: a study at tertiary neurocare center from south india. | biofilms are the source of persistent infections of many pathogenic microbes. they are responsible for nosocomial infection and also associated with many surgical conditions including indwelling medical devices such as ventriculoperitoneal shunt. a significant problem encountered in shunt procedures is obstruction followed by infection, with infection rate ranging from 2% to 27%, often with poor outcome. | 2017 | 28694609 |
| thymus vulgaris l. extract has antimicrobial and anti-inflammatory effects in the absence of cytotoxicity and genotoxicity. | this study evaluated the biological effects of the t. vulgaris l. extract., such as antimicrobial activity on planktonic cultures and mono- and polymicrobial biofilms, cytotoxicity, anti-inflammatory activity and genotoxicity. | 2017 | 28683409 |
| nbiochip, a lab-on-a-chip platform of mono- and polymicrobial biofilms for high-throughput downstream applications. | current in vitro techniques for the culture of microorganisms, and particularly of delicate microbial biofilms, are still mostly limited to low-density plates and manual labor and are not amenable to automation and true high-throughput (ht) applications. we have developed a novel fully automated platform for the formation of mono- and polymicrobial biofilms of staphylococcus aureus, pseudomonas aeruginosa, and candida albicans at the nanoscale level. the nbiochip is robotically printed, robustly ... | 2017 | 28680970 |
| effect of treatment with caspofungin on the diagnosis of fungal infections by gamma scintigraphy. | the aim of this work is to assess the influence of treatment with unlabeled-caspofungin, on the quality of diagnostic scintigraphic images of induced lesions in nude mice undergoing both bacterial and fungal infections and to determine the level of specificity of 99mtc-tricarbonyl-caspofungin to discriminate between fungal or bacterial infections. in vitro studies on the behaviour of the 99mtc-tricarbonyl-caspofungin complex binding percentage at different yeast concentrations of candida albican ... | 2017 | 28675994 |
| composition and antimicrobial activity of the essential oil from the branches of jacaranda cuspidifolia mart. growing in sichuan, china. | this study represents the first report on the chemical composition and antimicrobial activity of the essential oil from the branches of jacaranda cuspidifolia mart. thirty-three compounds were identified by gas chromatography-mass spectrometry (gc-ms) and the major constituents of the essential oil were palmitic acid (31.36%), (z) - 9,17-octadecadienal (12.06%), ethyl palmitate (3.81%), perhydrofarnesyl acetone (2.07%), γ-maaliene (1.88%), and cedro (1.42%) and 9,12-octadecadienoic acid ethyl es ... | 2017 | 28670931 |
| comparison of dna extraction methods used to detect bacterial and yeast dna from spiked whole blood by real-time pcr. | sepsis is the leading cause of death in intensive care units (icus) worldwide and its diagnosis remains a challenge. blood culturing is the gold standard technique for blood stream infection (bsi) identification. molecular tests to detect pathogens in whole blood enable early use of antimicrobials and affect clinical outcomes. here, using real-time pcr, we evaluated dna extraction using seven manual and three automated commercially available systems with whole blood samples artificially contamin ... | 2017 | 28669799 |
| bactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra. | cyclotides are a family of plant peptides characterized by a cystine knot embedded in a macrocyclic backbone. they bind to and disrupt phospholipid membranes, which explain their lytic activity on cells. in this study, we expose the full antibacterial potency of cyclotides by avoiding its inhibition by rich growth media assay conditions. for that purpose a two-step microdilution assay protocol was developed, using non-growing conditions during initial peptide incubation. a diverse set of cycloti ... | 2017 | 28669767 |
| soluble factors from biofilm of candida albicans and staphylococcus aureus promote cell death and inflammatory response. | the objective of this study was to better understand the effects of soluble factors from biofilm of single- and mixed-species candida albicans (c. albicans) and methicillin-sensitive staphylococcus aureus (mssa) cultures after 36 h in culture on keratinocytes (nok-si and hacat) and macrophages (j774a.1). soluble factors from biofilms of c. albicans and mssa were collected and incubated with keratinocytes and macrophages, which were subsequently evaluated by cell viability assays (mtt). lactate d ... | 2017 | 28666415 |
| isolation and characterization of sesquiterpenoids from cassia buds and their antimicrobial activities. | cassia buds, the immature fruits of cinnamomum cassia (lauraceae), are widely consumed as a food spice, dietary supplements, flavoring agents, and preservatives. in this study, cassia buds were phytochemically investigated for the first time, leading to the isolation of 2 new sesquiterpenoids (1 and 2) and 10 known sesquiterpenoids (3-12). their structures were determined by spectrometric and spectroscopic analyses, including nuclear magnetic resonance, high-resolution electrospray ionization ma ... | 2017 | 28665598 |
| thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis. | the aim of the present study was to develop thermoplastic polyurethane (tpu)-based intravaginal rings (ivrs) for prophylaxis and treatment of bacterial vaginosis via hot melt extrusion/injection molding. therefore, different tpu grades were processed in combination with lactic acid or metronidazole, targeting a sustained lactic acid release over a 28day-period and sustained metronidazole release over 4-7days. hot melt extrusion of lactic acid/tpu combinations required a lower extrusion temperatu ... | 2017 | 28663088 |
| chemical composition and antimicrobial activity of the essential oil of mentha mozaffarianii jamzad growing wild and cultivated in iran. | the aerial parts of wild and cultivated mentha mozaffarianii jamzad were collected at full flowering stage from two provinces (hormozgan and fars) of iran. the essential oils were extracted by a clevenger approach and analysed using gc and gc-ms. the main components in wild plants were piperitenone (33.85%), piperitone (21.18%), linalool (6.89%), pulegone (5.93%), 1, 8.cineole (5.49%), piperitenone oxide (5.17%) and menthone (4.69%) and in cultivated plants, cis-piperitone epoxide (28.89%), lina ... | 2017 | 28658991 |
| microbiological purity assessment of cosmetics used by one and several persons and cosmetics after their expiry date | microbiological purity of cosmetics provides safety of users during their use, prevents physicochemical changes of a preparation, infections and diseases of the skin. | 2017 | 28646837 |
| the antimicrobial spectrum of xeroform(®). | xeroform(®) is a petrolatum-based fine mesh gauze containing 3% bismuth tribromophenate. bismuth, similar to other metals, has antimicrobial properties. xeroform(®) has been used for decades in burn and plastic surgery as a donor site dressing and as a covering for wounds or partial thickness burns. despite this, the antimicrobial spectrum of xeroform(®) remains largely unknown. we examined the in-vitro efficacy of xeroform(®) against common burn pathogens using zone-of-inhibition methodology in ... | 2017 | 28641915 |
| pathogen-specific mortality in very low birth weight infants with primary bloodstream infection. | mortality in very low birth weight infants following microbiology confirmed primary bloodstream infections varies with the type of causative pathogen. given evidence from other studies that infections with gram negative bacteria and fungi cause a higher case fatality risk. we tried to confirm this in a nation-wide multi-center trial. | 2017 | 28640920 |
| whole blood profiling of bacillus calmette-guérin-induced trained innate immunity in infants identifies epidermal growth factor, il-6, platelet-derived growth factor-ab/bb, and natural killer cell activation. | vaccination of infants with bacillus calmette-guérin (bcg) activates both the innate and adaptive arms of the immune response. the antimycobacterial effects of these responses most likely account for the ability of bcg to protect against childhood forms of tuberculosis (tb). there is also evidence for a heterologous protective effect of bcg vaccination against tb-unrelated mortality in low birth weight infants. a possible mechanism of action of this effect, the induction of trained innate immuni ... | 2017 | 28634479 |
| variation of alkaloid contents and antimicrobial activities of papaver rhoeas l. growing in turkey and northern cyprus. | papaver rhoeas l. (papaveraceae) corn poppy, widely distributed in turkey, is used to make a cough syrup for children, as a tea for disturbed sleep, for pain relief and as a sedative in folk medicine. | 2017 | 28633584 |
| in vitro evaluation of antimicrobial activity of alimentary canal extracts from the red palm weevil, rhynchophorus ferrugineus olivier larvae. | the invasive red palm weevil, rhynchophorus ferrugineus olivier (coleoptera: curculionidae), is considered one of the world's most devastating insect pests to palm trees. it was observed that larvae of this pest are able to inhibit microbial growth on the rearing media when they start feeding and this observation has led us to study the effect of red palm weevils on various microbial species. the antimicrobial effect of extracts from different parts of the alimentary canal on gram positive bacte ... | 2017 | 28612029 |
| effect of supercritical carbon dioxide extraction parameters on the biological activities and metabolites present in extracts from arthrospira platensis. | arthrospira platensis was used to obtain functional extracts through supercritical carbon dioxide extraction (sfe-co₂). pressure (p), temperature (t), co-solvent (cx), static extraction (sx), dispersant (di) and dynamic extraction (dx) were evaluated as process parameters through a plackett-burman design. the maximum extract yield obtained was 7.48 ± 0.15% w/w. the maximum contents of bioactive metabolites in extracts were 0.69 ± 0.09 µg/g of riboflavin, 5.49 ± 0.10 µg/g of α-tocopherol, 524.46 ... | 2017 | 28604646 |
| in vitro antimicrobial potential of extracts and phytoconstituents from gymnema sylvestre r.br. leaves and their biosafety evaluation. | the in vitro antimicrobial screening of gymnema sylvestre leaves against 13 test pathogens established its broad spectrum activity with average inhibition zone ranging from 14 to 23 mm. the antimicrobial activity of the classically- optimized aqueous extract was enhanced up to 1.45 folds, when subjected to statistical optimization using response surface methodology (rsm) and was thermostable. ethyl acetate was found to be the best organic extractant with klebsiella pneumoniae 1 (31.5 mm) and sta ... | 2017 | 28587443 |
| testing antifungal vaccines in an animal model of invasive candidiasis and in human mucosal candidiasis. | the following article will concentrate on the ndv-3 anti-candida and staphylococcus vaccine. the vaccine is composed of the n-terminal portion of the candida albicans agglutinin-like sequence 3 protein (als3p) and aluminum hydroxide as adjuvant. the vaccine conferred protection to mice against experimental vaginal, oral, and intravenous challenge with c. albicans. due to the sequence and structural homology of the als3p with staphylococcus aureus surface proteins, the vaccine also protected agai ... | 2017 | 28585001 |
| totally implantable venous access devices in children with medical complexity: preliminary data from a tertiary care hospital. | children with special health-care needs are an emerging and consistent population. in a subset of children with medical complexity (cmc) a continuous access to the central vascular system is advisable to eliminate unnecessary pain and stress and to improve home management and palliative care. | 2017 | 28574141 |
| cytotoxic, anti-cancer, and anti-microbial effects of different extracts obtained from artemisia rupestris. | artemisia rupestris is a part of traditional kazakh folk medicine. extracts obtained from this plant are used to treat various diseases, including cancer. this study evaluates the anti-microbial, cytotoxic, and anti-cancer effects of different extracts of the plant. different extraction techniques were used and the resultant activities were compared. extracts of a. rupestris were prepared from the flowers plus the leaves and from the stems. the antimicrobial activity against candida albicans and ... | 2017 | 28569514 |
| antimicrobial and anti-biofilm properties of polypropylene meshes coated with metal-containing dlc thin films. | a promising strategy to reduce nosocomial infections related to prosthetic meshes is the prevention of microbial colonization. to this aim, prosthetic meshes coated with antimicrobial thin films are proposed. commercial polypropylene meshes were coated with metal-containing diamond-like carbon (me-dlc) thin films by the magnetron sputtering technique. several dissimilar metals (silver, cobalt, indium, tungsten, tin, aluminum, chromium, zinc, manganese, tantalum, and titanium) were tested and com ... | 2017 | 28560581 |
| chemical composition and antimicrobial activities of iranian propolis | with considering the importance of natural products for their remedial and therapeutic value, this research was aimed to analyze the chemical compositions and antimicrobial activity of four propolis samples from different areas of iran (chenaran, taleghan, morad beyg, and kalaleh) with various climates and flora. | 2017 | 28558440 |
| fabrication of denture base materials with antimicrobial properties. | acrylic resin denture base resins are colonized by oral and nonoral bacteria and candida species. this reservoir of microorganism causes denture stomatitis, which can be implicated in some life-threating infections in older denture wearers. | 2017 | 28552288 |
| investigation of antioxidant, antimicrobial and toxicity activities of lichens from high altitude regions of nepal. | several lichen species are reported to be used tradiationally in many theraupatic practices. many lichen species are reported as sources of several bioactive natural compounds. several lichen species of nepal are so far chemically unexplored. | 2017 | 28545438 |
| relative susceptibility of airway organisms to antimicrobial effects of nitric oxide. | nitric oxide (no) is released in the airway as a critical component of innate immune defense against invading pathogenic organisms. it is well documented that bacteriostatic and bactericidal effects of no are concentration-dependent. however, few data exist comparing relative susceptibility of common pathogens to no at physiologic concentrations. in this study we evaluated the effects of no on 4 common airway bacteria and 1 fungus, and examined the potential implications of discrepancies in sens ... | 2017 | 28544570 |
| effectiveness of non-fluoride and fluoride dentifrices for denture hygiene. | to compare the effectiveness of commonly used herbal/non-fluoride with fluoride dentifrices in order to eliminate pathogenic oral microorganisms from denture base material. | 2017 | 28539095 |
| green synthesis of silver nanoparticles using mentha pulegium and investigation of their antibacterial, antifungal and anticancer activity. | a simple and eco-friendly method for efficient synthesis of stable colloidal silver nanoparticles (agnps) using mentha pulegium extracts is described. a series of reactions was conducted using different types and concentrations of plant extract as well as metal ions to optimize the reaction conditions. agnps were characterized by using uv-vis spectroscopy, transmission electron microscopy, atomic force microscopy, dynamic light scattering, zetasizer, energy-dispersive x-ray spectroscopy (edax) a ... | 2017 | 28530184 |
| application of hyperosmotic nanoemulsions in wound healing: partial thickness injury model in swine. | objective: in this work, we introduce a novel hyperosmotic nanoemulsion (hne) topical agent for use in wound healing. these topical emulsion complexes combine a lipophilic thymol nanoemulsion with a hyperosmotic saccharide matrix. this combination has been previously shown to possess synergistic antimicrobial activity against a host of common and drug-resistant pathogens in vitro. approach: in this study, we present additional data to assess the safety and efficacy of these emulsions in a partia ... | 2017 | 28507786 |
| microbiological analysis of acute infections of the nail fold on the basis of bait thread test. | an acute infection of the nail fold, called paronychia, is a common clinical problem. the basis for the implementation of the treatment is the result of microbiological examination. due to the rapid and painful course of infection, usually an empirical antimicrobial treatment prior to obtaining microbiological test results is introduced. | 2017 | 28507488 |
| broad spectrum macromolecular antimicrobials with biofilm disruption capability and in vivo efficacy. | in this study, antimicrobial polymers are synthesized by the organocatalytic ring-opening polymerization of an eight-membered heterocyclic carbonate monomer that is subsequently quaternized with methyl iodide. these polymers demonstrate activity against clinically relevant gram-positive staphylococcus epidermidis and staphylococcus aureus, gram-negative escherichia coli and pseudomonas aeruginosa, and fungus candida albicans with fast killing kinetics. importantly, the polymer efficiently inhibi ... | 2017 | 28504348 |
| salvia officinalis l. essential oils from spain: determination of composition, antioxidant capacity, antienzymatic, and antimicrobial bioactivities. | four essential oils (eos) from salvia officinalis l. cultivated in spain (murcia province) were analyzed by gas chromatography coupled with mass spectrometry (gc/ms) to determine their relative and absolute compositions. the main components were α-thujone (22.8 - 41.7%), camphor (10.7 - 19.8%), 1,8-cineole (4.7 - 15.6%), and β-thujone (6.1 - 15.6%). enantioselective gas chromatography identified (-)-α-thujone and (+)-camphor as the main enantiomers in all the analyzed eos. furthermore, when the ... | 2017 | 28477412 |
| synthesis and in vitro biological evaluation of novel coumarin derivatives containing isoxazole moieties on melanin synthesis in b16 cells and inhibition on bacteria. | a novel series of coumarin derivatives 6a-o, bearing isoxazole moieties were designed and synthesized. after that, they were evaluated for melanin synthesis in murine b16 cells and inhibitory effect on the growth of ca (candida albicans), ec (escherichia coli), sa (staphylococcus aureus). it was found that eleven compounds (6b-f, 6j-o) showed a better activity on melanin synthesis than positive control (8-mop). among them, compounds 6d (242%) and 6f (390%), with nearly 1.6 and 2.6-fold potency c ... | 2017 | 28476568 |
| investigation of antimicrobial, antioxidant, and xanthine oxidase--inhibitory activities of phellinus (agaricomycetes) mushroom species native to central europe. | ten representative central european phellinoid hymenochaetaceae species (phellinus sensu lato) were selected to examine their potential pharmacological activity. in this study 40 organic (n-hexane, chloroform, 50% methanol) and aqueous extracts with different polarities were analyzed for their antimicrobial, antioxidant, and xanthine oxidase (xo)--inhibitory properties. fomitiporia robusta, fuscoporia torulosa, phellopilus nigrolimitatus, and porodaedalea chrysoloma showed moderate antibacterial ... | 2017 | 28845768 |
| structural insights into the mode of action of the peptide antibiotic copsin. | defensins are a class of cysteine-rich antimicrobial peptides, expressed by virtually all eukaryotes as part of their innate immune response. due to their unique mode of action and rapid killing of pathogenic microbes, defensins are considered promising alternatives to clinically applied antibiotics. copsin is a defensin-like peptide, previously identified in the mushroom coprinopsis cinerea. it is active against a range of gram positive bacteria through binding to the peptidoglycan precursor li ... | 2017 | 28825809 |
| anti-biofilm effects of anthranilate on a broad range of bacteria. | anthranilate, one of tryptophan degradation products has been reported to interfere with biofilm formation by pseudomonas aeruginosa. here, we investigated the effects of anthranilate on biofilm formation by various bacteria and the mechanisms responsible. anthranilate commonly inhibited biofilm formation by p. aeruginosa, vibrio vulnificus, bacillus subtilis, salmonella enterica serovar typhimurium, and staphylococcus aureus, and disrupted biofilms preformed by these bacteria. because anthranil ... | 2017 | 28819217 |
| upregulation and identification of antibiotic activity of a marine-derived streptomyces sp. via co-cultures with human pathogens. | marine natural product drug discovery has begun to play an important role in the treatment of disease, with several recently approved drugs. in addition, numerous microbial natural products have been discovered from members of the order actinomycetales, particularly in the genus streptomyces, due to their metabolic diversity for production of biologically active secondary metabolites. however, many secondary metabolites cannot be produced under laboratory conditions because growth conditions in ... | 2017 | 28800088 |
| chemical sterilization of allograft dermal tissues. | common terminal sterilization methods are known to alter the natural structure and properties of soft tissues. one approach to providing safe grafts with preserved biological properties is the combination of a validated chemical sterilization process followed by an aseptic packaging process. this combination of processes is an accepted method for production of sterile healthcare products as described in ansi/aami st67:2011. this article describes the validation of the peracetic acid and ethanol- ... | 2017 | 28799106 |
| in vitro antimicrobial activities and mechanism of 1-octen-3-ol against food-related bacteria and pathogenic fungi. | 1-octen-3-ol, known as mushroom alcohol, is a natural product extracted from fungi and plants. its antimicrobial activities against five common food-related bacteria and two pathogenic fungi were evaluated in this paper, including staphylococcus aureus, bacillus subtilis, staphylococcus epidermidis, escherichia coli, pseudomonas aeruginosa, fusarium tricinctum and fusarium oxysporum. the results showed that 1-octen-3-ol had a strong antibacterial activity against the tested bacteria, especially ... | 2017 | 28794307 |
| functional redundancy of division specific penicillin-binding proteins in bacillus subtilis. | bacterial cell division involves the dynamic assembly of a diverse set of proteins that coordinate the invagination of the cell membrane and synthesis of cell wall material to create the new cell poles of the separated daughter cells. penicillin-binding protein pbp 2b is a key cell division protein in bacillus subtilis proposed to have a specific catalytic role in septal wall synthesis. unexpectedly, we find that a catalytically inactive mutant of pbp 2b supports cell division, but in this backg ... | 2017 | 28792086 |
| saccharopolyspora hattusasensis sp. nov., isolated from soil. | a saccharopolyspora strain, designated cr3506(t), isolated from a soil sample collected from sungurlu, corum, turkey, was examinated using a polyphasic approach. phylogenetic analysis based on an almost-complete 16s rrna gene sequence analysis showed that the strain is closely related to the type strains of saccharopolyspora spinosa nrrl 18395(t) (99.1%), saccharopolyspora phatthalungensis nrrl b-24798(t) (98.4%) and saccharopolyspora shandongensis 88(t) (98.1%); low levels of dna-dna relatednes ... | 2017 | 28785826 |
| physakengoses k-q, seven new sucrose esters from physalis alkekengi var. franchetii. | seven sucrose esters, physakengoses k-q (1-7) were isolated from the aerial parts of physalis alkekengi var. franchetii. their structures were elucidated on the basis of extensive spectroscopic analyses and chemical methods. these new compounds were tested for their antimicrobial abilities against staphylococcus aureus, bacillus subtilis, pseudomonas aeruginosa and escherichia coli. among the isolated sucrose esters, compounds 1-5 showed potent antibacterial activity with mic values ranging from ... | 2017 | 28779658 |
| preparation, antioxidant and antimicrobial evaluation of hydroxamated degraded polysaccharides from enteromorpha prolifera. | in order to improve the antioxidant and antimicrobial abilities, hydroxamated degraded polysaccharides from enteromorpha prolifera (hcdpe) were prepared from the corresponding carboxymethylated degraded polysaccharides (cdpe). hcdpe was characterized by ft-ir. the weight-average molecular weight of hcdpe was determined as 55.4kda. the in vitro antioxidant activity of hcdpe was evaluated by determining the radical (1,1-diphenyl-2-picrylhydrazyl (dpph), hydroxyl and superoxide anion radicals) scav ... | 2017 | 28764023 |
| synthesis and antimicrobial activity of chiral quaternary n-spiro ammonium bromides with 3',4'-dihydro-1'h-spiro[isoindoline-2,2'-isoquinoline] skeleton. | a new class of highly functionalized tetrahydroisoquinolines with a quaternary carbon stereocenter was synthesized starting from an easily accessible l-tartaric acid. nine strains of bacteria (staphylococcus aureus, streptococcus pyogenes, streptococcus mutans, streptococcus salivarius, bacillus subtilis, enterococcus faecalis, moraxella catarrhalis, escherichia coli, campylobacter jejuni) were used for the determination of minimal inhibitory concentration (mic) and minimal bactericidal concentr ... | 2017 | 28740363 |
| construction of multilayer alginate hydrogel beads for oral delivery of probiotics cells. | multilayer alginate hydrogel beads (mahbs), which were prepared by emulsion method, had been fabricated via the ionic crosslinking between calcium ion (ca(2+)) and carboxylic group of alginate and utilized as encapsulating material for oral delivery of a model probiotic bacteria bifidobacterium breve. optical and fluorescence microscopy obviously showed the microorganism cells were encapsulated in the core beads. the viability of b. breve cells encapsulated in mahbs was significantly enhanced co ... | 2017 | 28736041 |
| discrimination of bacteria by rapid sensing their metabolic volatiles using an aspiration-type ion mobility spectrometer (a-ims) and gas chromatography-mass spectrometry gc-ms. | the objective of our study was to investigate whether one may quickly and reliably discriminate different microorganism strains by direct monitoring of the headspace atmosphere above their cultures. headspace samples above a series of in vitro bacterial cultures were directly interrogated using an aspiration type ion mobility spectrometer (a-ims), which produced distinct profiles ("fingerprints") of ion currents generated simultaneously by the detectors present inside the ion mobility cell. data ... | 2017 | 28734362 |
| a prospective randomised trial of isolated pathogens of surgical site infections (ssi). | every surgical wound is colonized by bacteria, but only a small percentage displays symptoms of infection. the distribution of pathogens isolated in surgical site infections has not significantly changed over the last decades. staph. aureus, coag(-) staphylococci, enterococcus spp and e. coli are the main strains appearing. in addition, a continuously rising proportion of surgical site infections caused by resistant bacterial species (mrsa, c. albicans) has been reported. | 2017 | 28761643 |
| implementation of the new virtuo blood culture system: evaluation and comparison to the 3d system using simulated blood cultures. | to evaluate the performances of the newly approved bact/alert virtuo blood culture system for the recovery of bloodstream pathogens and compare it to the bact/alert 3d system. | 2017 | 28583022 |
| antimicrobial susceptibility of pathogens isolated from surgical site infections in japan: comparison of data from nationwide surveillance studies conducted in 2010 and 2014-2015. | a nationwide survey was conducted in japan from 2014 to 2015 to investigate the antimicrobial susceptibility of pathogens isolated from surgical site infections (ssi). the resulting data were compared with that obtained in an earlier survey, conducted in 2010. seven main organisms were collected, and 883 isolates were studied. a significant reduction in methicillin resistance was observed among staphylococcus aureus isolates, dropping from 72.5% in 2010 to 53.8% in 2014-2015 (p < 0.001). mrsa is ... | 2017 | 28391954 |
| cat-scratch disease presenting as multiple hepatic lesions: case report and literature review. | although infectious diseases are the most prevalent cause of fevers of unknown origin (fuo), this diagnosis remains challenging in some pediatric patients. imaging exams, such as computed tomography (ct) are frequently required during the diagnostic processes. the presence of multiple hypoattenuating scattered images throughout the liver associated with the history of cohabitation with cats should raise the suspicion of the diagnosis of cat-scratch disease (csd), although the main etiologic agen ... | 2017 | 28580326 |
| probiotic strawberry yogurts: microbiological, chemical and sensory properties. | this study was performed to determine the viability of lactobacillus acidophilus and bifidobacterium bifidum in yogurt made with strawberry marmalade (sm) and to examine the quality properties of probiotic yogurt. acidity, ph, bacterial counts and sensory analysis of the yogurt samples were investigated on days 1, 3, 5, 7, 10 and 14 during storage at 4 °c. the survival rate of l. acidophilus was greater than that of b. bifidum. the viability of l. acidophilus decreased during the storage period, ... | 2017 | 28417292 |
| human milk oligosaccharide categories define the microbiota composition in human colostrum. | human milk oligosaccharides (hmos) are structurally diverse unconjugated glycans with a composition unique to each lactating mother. while hmos have been shown to have an impact on the development of infant gut microbiota, it is not well known if hmos also already affect milk microbial composition. to address this question, we analysed eleven colostrum samples for hmo content by high-pressure liquid chromatography and microbiota composition by quantitative pcr. higher total hmo concentration was ... | 2017 | 28726512 |
| simultaneous detection of 13 key bacterial respiratory pathogens by combination of multiplex pcr and capillary electrophoresis. | lower respiratory tract infections continue to pose a significant threat to human health. it is important to accurately and rapidly detect respiratory bacteria. to compensate for the limits of current respiratory bacteria detection methods, we developed a combination of multiplex polymerase chain reaction (pcr) and capillary electrophoresis (mpce) assay to detect thirteen bacterial pathogens responsible for lower respiratory tract infections, including streptococcus pneumoniae, haemophilus influ ... | 2017 | 28807095 |
| transmission fitness in co-colonization and the persistence of bacterial pathogens. | humans are often colonized by polymorphic bacteria such as streptococcus pneumoniae, bordetella pertussis, staphylococcus aureus, and haemophilus influenzae. two co-colonizing pathogen clones may interact with each other upon host entry and during within-host dynamics, ranging from competition to facilitation. here we examine the significance of these exploitation strategies for bacterial spread and persistence in host populations. we model sis epidemiological dynamics to capture the global beha ... | 2017 | 28741105 |
| inactivation of model viruses and bacteria in human fresh frozen plasma using riboflavin and long wave ultraviolet rays. | pathogen reduction technologies are among methods to eliminate transfusion transmitted infections. mirasol method using riboflavin in combination with ultraviolet rays is one of them. the aims of this study were to investigate the effectiveness of mirasol method to inactivate some model pathogens as well as examination of the sensitivity of plasma proteins after treatment. | 2017 | 28775824 |
| lung transplantation in cystic fibrosis patients with difficult to treat lung infections. | in cystic fibrosis (cf) patients with end-stage pulmonary disease, lung transplantation (ltx) remains a life-extending therapy with good outcome in most patients. despite early concern about chronic pretransplantation infections in the context of posttransplantation immunosuppression, typical cf-associated organisms such as pseudomonas aeruginosa turned out to be quite well manageable and associated with favorable outcomes in transplanted cf patients, even in patients with highly resistant strai ... | 2017 | 28858970 |
| inhibition of bacterial biofilms by carboxymethyl chitosan combined with silver, zinc and copper salts. | investigation of the antimicrobial action of carboxymethyl chitosan (cmch) is among the alternative approaches in the control of pathogenic microorganisms. this study aimed to screen the toxicity using the brine shrimp lethality assay and to investigate the inhibitory activity of carboxymethyl in isolation or in combination with silver nitrate, copper sulfate and zinc sulfate on biofilm formation by staphylococcus aureus atcc 6538, staphylococcus epidermidis atcc 12228, kocuria rhizophila atcc 9 ... | 2017 | 28756196 |
| understanding the entanglement: neutrophil extracellular traps (nets) in cystic fibrosis. | cystic fibrosis (cf) is an autosomal recessive disorder caused by mutations in the gene that codes for the cf trans-membrane conductance regulator. these mutations result in abnormal secretions viscous airways of the lungs, favoring pulmonary infection and inflammation in the middle of neutrophil recruitment. recently it was described that neutrophils can contribute with disease pathology by extruding large amounts of nuclear material through a mechanism of cell death known as neutrophil extrace ... | 2017 | 28428948 |
| within-host evolution of burkholderia pseudomallei during chronic infection of seven australasian cystic fibrosis patients. | cystic fibrosis (cf) is a genetic disorder characterized by progressive lung function decline. cf patients are at an increased risk of respiratory infections, including those by the environmental bacterium burkholderia pseudomallei, the causative agent of melioidosis. here, we compared the genomes of b. pseudomallei isolates collected between ~4 and 55 months apart from seven chronically infected cf patients. overall, the b. pseudomallei strains showed evolutionary patterns similar to those of o ... | 2017 | 28400528 |
| ag(i) camphorimine complexes with antimicrobial activity towards clinically important bacteria and species of the candida genus. | the present work follows a previous report describing the antibacterial activity of silver camphorimine complexes of general formula [ag(no3)l]. the synthesis and demonstration of the antifungal and antibacterial activity of three novel [ag(no3)l] complexes (named 1, 2 and 3) is herein demonstrated. this work also shows for the first time that the previously studied complexes (named 4 to 8) also exert antifungal activity. the antibacterial activity of complexes was evaluated against staphylococc ... | 2017 | 28486529 |
| bacterial bloodstream infections in a tertiary infectious diseases hospital in northern vietnam: aetiology, drug resistance, and treatment outcome. | bloodstream infections (bsis) are associated with high morbidity and mortality worldwide. however their aetiology, antimicrobial susceptibilities and associated outcomes differ between developed and developing countries. systematic data from vietnam are scarce. here we present aetiologic data on bsi in adults admitted to a large tertiary referral hospital for infectious diseases in hanoi, vietnam. | 2017 | 28701159 |
| in vitro evaluation of cytotoxic, anti-proliferative, anti-oxidant, apoptotic, and anti-microbial activities of cladonia pocillum. | the aim of this study was to investigate the anti-proliferative, apoptotic, cytotoxic, and anti-oxidant effects of extracts from the lichen cladonia pocillumon human breast cancer cells (mcf-7), and to characterize the anti-microbial features. mcf-7 cells were treated with methanolic c. pocillum extract for 24h. the cytotoxicity of the extract was tested with mtt. moreover, its anti-proliferative effects were examined with immunocytochemical method. apoptosis and biochemical parameters were det ... | 2017 | 28838343 |
| photodynamic inactivation of microorganisms sensitized by cationic bodipy derivatives potentiated by potassium iodide. | the photodynamic inactivation mediated by 1,3,5,7-tetramethyl-8-[4-(n,n,n-trimethylamino)phenyl]-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 3 and 8-[4-(3-(n,n,n-trimethylamino)propoxy)phenyl]-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene 4 was investigated on staphylococcus aureus, escherichia coli and candida albicans. in vitro experiments indicated that bodipys 3 and 4 were rapidly bound to microbial cells at short incubation periods. also, fluorescence microscopy images showed green emission of ... | 2017 | 28836645 |
| branched peptides: acridine and boronic acid derivatives as antimicrobial agents. | the emergence of microbial resistance presents a challenge in the development of next generation therapeutics. herein, we report the discovery of branched peptides decorated with acridine and boronic acid moieties with potent antimicrobial activity. the results revealed minimal inhibitory concentrations (mics) as low as 1 μg/ml against staphylococcus aureus, candida albicans, and escherichia coli. these peptides were nonhemolytic, and significantly inhibited growth of c. albicans in suspension a ... | 2017 | 28835795 |
| chemical and antimicrobial analyses of sideritis romana l. subsp. purpurea (tal. ex benth.) heywood, an endemic of the western balkan. | a comprehensive study on essential oil and different solvent extracts of sideritis romana l. subsp. purpurea (tal. ex benth.) heywood (lamiaceae) from montenegro is reported. the gas chromatography-mass spectrometry analysis of the essential oil revealed a total of 43 components with bicyclogermacrene (23.8%), germacrene d (8%), (e)-caryophyllene (7.9%) and spathulenol (5.5%) as the major ones. sesquiterpenoid group was found to be the most dominant one (64.8%), with 19.9% of the oxygenated form ... | 2017 | 28832536 |
| investigation of effect of 1,8-cineole on antimicrobial activity of chlorhexidine gluconate. | chlorhexidine belongs to a group of medicines called antiseptic antibacterial agents. chlorhexidine is commonly used for the care and clean off the skin, hands, and wounds. in recent years, medicinal and aromatic plants have been used for prevention of disease, maintaining health, and improving disease in traditional and modern medicine as a medicament. according to recent research, cineole is the isolated active agent of eucalyptus oil and possesses antimicrobial activity. it was demonstrated t ... | 2017 | 28827963 |
| composition and antioxidant, antienzymatic and antimicrobial activities of volatile molecules from spanish salvia lavandulifolia (vahl) essential oils. | the current study describes the composition of salvia lavandulifolia (vahl) essential oils (sleos) obtained from plants cultivated in murcia (spain), as determined by gas chromatography. relative and absolute concentrations, the enantiomeric ratios of chiral compounds and the in vitro antioxidant, antienzymatic and antimicrobial activities are described. the main components of the sleos were camphor, 1,8-cineole, camphene and α-pinene, and the main enantiomers were (+)-camphor and (-)-camphene. ... | 2017 | 28825692 |
| candida albicans/staphylococcus aureus dual-species biofilm as a target for the combination of essential oils and fluconazole or mupirocin. | the effectiveness of essential oils (eos), fluconazole (flu) and mupirocin (mup) used alone or in combination against mono-species and mixed candida albicans/staphylococcus aureus biofilms was examined. an experimentally established dual-species biofilm model, verified by fluorescence microscopy and viable cell counting, was used. selected commercial eos were tested: geranium, citronella and clove oils, which have been chemically characterized and found to differ in the content of the main compo ... | 2017 | 28823093 |
| [to the state of the fetoplacental complex in women with the threat of abortion]. | the goal is a comprehensive study of the morphofunctional state of the mother-placenta-fetus system in placental insufficiency and infection. 250 pregnant and puerperas for the period 2008-2014 were examined. detection of bacterial flora was carried out in 35 pregnant women aged 20.4±0.8 years with the threat of abortion from an early gestation period and a prolonged persistent infection of the genitals, bacterial vaginosis. methods are applied: culture, ion chromatography, gas-liquid chromatogr ... | 2017 | 28820412 |
| marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete clade mar4. | six cytotoxic and antimicrobial metabolites of a new bromo-phenazinone class, the marinocyanins a-f (1-6), were isolated together with the known bacterial metabolites 2-bromo-1-hydroxyphenazine (7), lavanducyanin (8, ws-9659a) and its chlorinated analog ws-9659b (9). these metabolites were purified by bioassay-guided fractionation of the extracts of our mar4 marine actinomycete strains cns-284 and cny-960. the structures of the new compounds were determined by detailed spectroscopic methods and ... | 2017 | 28814819 |
| bioactive potential of 3d-printed oleo-gum-resin disks: b. papyrifera, c. myrrha, and s. benzoin loading nanooxides-tio2, p25, cu2o, and moo3. | this experimental study investigates the bioactive potential of filaments produced via hot melt extrusion (hme) and intended for fused deposition modeling (fdm) 3d printing purposes. the oleo-gum-resins from benzoin, myrrha, and olibanum in pure state and also charged with 10% of metal oxide nanoparticles, tio2, p25, cu2o, and moo3, were characterized by ultraviolet-visible (uv-vis) and fourier transform infrared (ftir) spectroscopy, energy-dispersive x-ray microanalysis (edxma), scanning electr ... | 2017 | 28811751 |
| bioactive mesoporous silica nanostructures with anti-microbial and anti-biofilm properties. | the increasing rate of antibiotic resistant bacteria associated with nosocomial infections in severely ill patients has urged the need for new antibacterial therapies. nanostructured materials represent emerging innovative approaches to controlled delivery of different antimicrobial drugs. delivery systems encapsulating natural compounds with antibacterial effects, such as essential oils have shown a great potential. herein we report the development of sio2 mesoporous nanosystems loaded with euc ... | 2017 | 28797969 |
| cold atmospheric pressure plasmas exhibit antimicrobial properties against critical bacteria and yeast species. | cold atmospheric pressure plasmas (capps) have been used to sterilise implant materials and other thermally unstable medical products and to modify chemical surfaces. this study investigates the antimicrobial effect of the gas and input power used to generate capps on microorganisms causing skin infections, such as staphylococcus aureus, pseudomonas aeruginosa, candida albicans and malassezia pachydermatis. | 2017 | 28795887 |
| nanoscale silver depositions inhibit microbial colonization and improve biocompatibility of titanium abutments. | although titanium dental implants are biocompatible, exhibit excellent corrosion resistance and high mechanical resistance, the material fails in providing resistance to infection because it exhibits poor antimicrobial activity. to address these issues, we deposited silver onto titanium abutments (grade 5 titanium discs) using direct current (dc) sputtering and assessed the antimicrobial activity and biocompatibility of the modified implant material. atomic absorption spectrometry and x-ray phot ... | 2017 | 28783506 |
| thermo-and ph-sensitive hydrogel membranes composed of poly(n-isopropylacrylamide)-hyaluronan for biomedical applications: influence of hyaluronan incorporation on the membrane properties. | interpenetrating hydrogel membranes consisting of ph-sensitive hyaluronan (ha) and thermo-sensitive poly(n-isopropylacrylamide) (pnipaam) were synthesized using redox polymerization, followed by n,n-methylenebisacrylamide (bis) and epichlorohydrin (epi) were added as chemical crosslinkers. the interaction between membrane compositions has been characterized by ftir spectroscopy and discussed intensively. the result indicates that ha incorporation in membranes increase the gel fraction, swelling ... | 2017 | 28780413 |
| thymus vulgaris l. and thymol assist murine macrophages (raw 264.7) in the control of in vitro infections by staphylococcus aureus, pseudomonas aeruginosa, and candida albicans. | microorganisms are capable to combat defense cells by means of strategies that contribute to their stabilization and proliferation in invaded tissues. frequently antimicrobial-resistant strains appear; therefore, alternative methods to control them must be investigated, for example, the use of plant products. the capacity of the thyme extract (thymus vulgaris l.) and phytocompound thymol in the control of in vitro infections by staphylococcus aureus, pseudomonas aeruginosa, and candida albicans ... | 2017 | 28752199 |
| colorimetric sensing of toxic metal and antibacterial studies by using bioextract synthesized silver nanoparticles. | here, we report the simple and cost effective colorimetric technique for the determination of toxic metals (hg(2+)) in aqueous sample by using bioextract silver nanoparticles (agnps). the indigenous agnps were synthesised by green and ecologically friendly style using extract of fig (ficus carica) leaf. the synthesized agnps were confirmed by uv-vis spectroscopy, ft-ir spectroscopy, and scanning electron microscopy methods. the synthesis of agnps was observed by its colour changing from light ye ... | 2017 | 28748516 |
| essential oils and hydrophilic extracts from the leaves and flowers of succisa pratensis moench. and their biological activity. | this study was undertaken to evaluate the antioxidant activity of methanol and water extracts from succisa pratensis moench (dipsacaceae) leaves and flowers as well as the chemical composition of the essential oils found in them and the antimicrobial activity of the oils and extracts thereof. | 2017 | 28744918 |
| antimicrobial, modulatory and chemical analysis of the oil of croton limae. | croton sp. are plants with a well-reported antimicrobial activity. croton limae a.p. gomes, m.f. sales p.e. berry (euphorbiaceae), known as 'marmeleiro-prateado', is commonly used to manage abdominal pain in brazil. | 2017 | 28738715 |
| interactions of the antimicrobial peptide nisin z with conventional antibiotics and the use of nanostructured lipid carriers to enhance antimicrobial activity. | antimicrobial resistance is an imminent threat to the effective prevention and treatment of bacterial infections and alternative antimicrobial strategies are desperately needed. antimicrobial peptides (amps) may be promising alternatives to current antibiotics or act as adjuvants to enhance antibiotic potency. additionally, the use of biodegradable lipid nanoparticles can enhance the antibacterial activity of antibiotics and antimicrobial peptides. in this study, the interaction of the amps, nis ... | 2017 | 28461263 |
| in situ green synthesis of antimicrobial carboxymethyl chitosan-nanosilver hybrids with controlled silver release. | in order to fabricate antimicrobial carboxymethyl chitosan-nanosilver (cmc-ag) hybrids with controlled silver release, this study demonstrated comparable formation via three synthetic protocols: 1) carboxymethyl chitosan (cmc) and glucose (adding glucose after agno3), 2) cmc and glucose (adding glucose before agno3), and 3) cmc only. under principles of green chemistry, the synthesis was conducted in an aqueous medium exposed to microwave irradiation for 10 minutes with nontoxic chemicals. the s ... | 2017 | 28458539 |
| changing antimicrobial resistance pattern of isolates from an icu over a 3 year period. | to study the changing patterns of antimicrobial resistance in gram negative bacilli esp. escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa species and gram positive staphylococcus aureus isolates from a 37 bedded icu of a private hospital. | 2017 | 28457027 |
| biodegradation of ciprofloxacin by white rot fungus pleurotus ostreatus. | unrestricted and reckless use of antibiotics has resulted in their accumulation in environment. this, in turn, has led to the emergence of multiple drug-resistant microbes. the present study focuses on degradation of ciprofloxacin (cip) by an edible white rot fungus pleurotus ostreatus. effect of cip was determined on radial growth and biomass of p. ostreatus. titrimetric and spectrophotometric assays were carried out to assess the degrading potential of p. ostreatus towards cip. it was found th ... | 2017 | 28452015 |
| vancomycin-modified fe3o4@sio2@ag microflowers as effective antimicrobial agents. | nanomaterials combined with antibiotics exhibit synergistic effects and have gained increasing interest as promising antimicrobial agents. in this study, vancomycin-modified magnetic-based silver microflowers (van/fe3o4@sio2@ag microflowers) were rationally designed and prepared to achieve strong bactericidal ability, a wide antimicrobial spectrum, and good recyclability. high-performance fe3o4@sio2@ag microflowers served as a multifunction-supporting matrix and exhibited sufficient magnetic res ... | 2017 | 28450783 |
| hypericum perforatum incorporated chitosan films as potential bioactive wound dressing material. | recent studies in wound dressing applications offer new therapies and promote wound healing process. the aim of this study was to develop hypericum perforatum (st john's wort) oil incorporated chitosan films for wound dressing applications. h. perforatum oil as a potential therapeutic agent was encapsulated in chitosan film to achieve a better wound dressing material. oil incorporated chitosan films were successfully prepared by solvent casting method in different oil concentrations (0.25-1.5%v/ ... | 2017 | 28450246 |
| arginine-lysine positional swap of the ll-37 peptides reveals evolutional advantages of the native sequence and leads to bacterial probes. | antimicrobial peptides are essential components of the innate immune system of multicellular organisms. although cationic and hydrophobic amino acids are known determinants of these amphipathic molecules for bacterial killing, it is not clear how lysine-arginine (k-r) positional swaps influence peptide structure and activity. this study addresses this question by investigating two groups of peptides (gf-17 and 17biphe2) derived from human cathelicidin ll-37. k-r positional swap showed little eff ... | 2017 | 28450045 |
| seawater drowning-associated pneumonia: a 10-year descriptive cohort in intensive care unit. | pneumonia is one of the major complications of drowning, but the optimal empirical antibiotic treatment is not clearly defined. multidrug-resistant (mdr) bacteria and fungi have been identified in a recent series of freshwater drowning-associated pneumonia. however, microbial data in seawater drowning are scarce. the objective of the study is to describe the microorganisms isolated in early respiratory specimens obtained from seawater drowning-associated pneumonia and to provide their antibiotic ... | 2017 | 28447330 |
| identification and measurement of staphylococcal enterotoxin m from staphylococcus aureus isolate associated with staphylococcal food poisoning. | staphylococcus aureus produces a wide variety of staphylococcal enterotoxins (ses, sea to sex), which are responsible for staphylococcal food poisoning. this study is aimed to establish a system to detect staphylococcal enterotoxin m (sem) protein in food matrixes. in the present study, sem gene was characterized in a s. aureus isolate h4 associated with food poisoning. the amino acid sequence of the deduced sem protein was same as that of previously identified sem from s. aureus 04-02981. subse ... | 2017 | 28444877 |
| tat-functionalized liposomes for the treatment of meningitis: an in vitro study. | bacterial meningitis has become a global concern, because of the emergence of antibiotic-resistant bacteria. it has been demonstrated that liposomes can enter bacteria, thus providing a possible treatment for numerous infections, including meningitis. fusogenic liposomes are ph-sensitive with a high capacity to fuse with the bacteria membrane and promote intracellular drug release. moreover, this ability can be improved by using cell-penetrating peptides (such as tat47-57, which is a peptide der ... | 2017 | 28442909 |
| design of antibacterial poly(ether sulfone) membranes via covalently attaching hydrogel thin layers loaded with ag nanoparticles. | to inhibit bacteria attachment and the subsequent formation of biofilms on poly(ether sulfone) (pes) membranes, poly(sulfobetaine methacrylate)/poly(sodium acrylate) antibacterial hydrogel thin layers were covalently attached onto the membranes, followed by loading with ag nanoparticles. in our strategy, double bonds were firstly introduced onto the pes membrane surfaces to provide anchoring sites, and then the hydrogel layers were synthesized on the membrane surfaces via uv light-initiated cros ... | 2017 | 28440618 |
| antibiogram profile of septic meningitis among children in duhok, iraq. | to determine the prevalence of bacteria in the cerebrospinal fluid (csf), and the antibiogram profile in pediatric patients with suspected meningitis. methods: this descriptive study was conducted between january 2014 and january 2016 in the hevi paediatric teaching hospital in duhok, iraq. the csf samples were withdrawn from 432 pediatric patients suspected of meningitis. the samples were cultured, and antibiotic sensitivity tests were performed. results: there were 33 (7.6%) culture positive ... | 2017 | 28439602 |
| enhanced antibacterial metabolite production through the application of statistical methodologies by a streptomyces nogalater niist a30 isolated from western ghats forest soil. | streptomyces strains isolated from nelliyampathy forest soil of western ghats, kerala, india were evaluated for their antibacterial efficacy against two indicator pathogenic bacteria (escherichia coli and staphylococcus aureus). among 140 strains tested, sixteen recorded potent antibacterial properties and were further screened against eleven bacterial pathogens. a strain identified as streptomyces nogalater and designated as niist a30 exhibited maximum inhibition against all the test pathogens. ... | 2017 | 28437452 |