Publications

experimental infection of cats with afipia felis and various bartonella species or subspecies.	based upon prior studies, domestic cats have been shown to be the natural reservoir for bartonella henselae, bartonella clarridgeiae and bartonella koehlerae. however, other bartonella species, such as bartonella vinsonii subsp. berkhoffii, bartonella quintana or bartonella bovis (ex weissii) have been either isolated from or bartonella dna sequences pcr amplified and sequenced. in the late 1980s, before b. henselae was confirmed as the etiological agent of cat scratch disease, afipia felis had ...	2014	24972870
molecular detection of zoonotic bartonellae (b. henselae, b. elizabethae and b. rochalimae) in fleas collected from dogs in israel.	fleas represent an acknowledged burden on dogs worldwide. the characterization of flea species infesting kennel dogs from two localities in israel (rehovot and jerusalem) and their molecular screening for bartonella species (rhizobiales: bartonellaceae) was investigated. a total of 355 fleas were collected from 107 dogs. the fleas were morphologically classified and molecularly screened targeting the bartonella 16s-23s internal transcribed spacer (its). of the 107 dogs examined, 80 (74.8%) were ...	2015	25865162
fleas and flea-associated bartonella species in dogs and cats from peru.	in the present study, we investigated 238 fleas collected from cats and dogs in three regions of peru (ancash, cajamarca, and lima) for the presence of bartonella dna. bartonella spp. were detected by amplification of the citrate synthase gene (16.4%) and the 16s-23s intergenic spacer region (20.6%). bartonella rochalimae was the most common species detected followed by bartonella clarridgeiae and bartonella henselae. our results demonstrate that dogs and cats in peru are infested with fleas har ...	2015	26363063
relationship between the presence of bartonella species and bacterial loads in cats and cat fleas (ctenocephalides felis) under natural conditions.	cats are considered the main reservoir of three zoonotic bartonella species: bartonella henselae, bartonella clarridgeiae, and bartonella koehlerae. cat fleas (ctenocephalides felis) have been experimentally demonstrated to be a competent vector of b. henselae and have been proposed as the potential vector of the two other bartonella species. previous studies have reported a lack of association between the bartonella species infection status (infected or uninfected) and/or bacteremia levels of c ...	2015	26070666
bartonella spp. bacteremia in blood donors from campinas, brazil.	bartonella species are blood-borne, re-emerging organisms, capable of causing prolonged infection with diverse disease manifestations, from asymptomatic bacteremia to chronic debilitating disease and death. this pathogen can survive for over a month in stored blood. however, its prevalence among blood donors is unknown, and screening of blood supplies for this pathogen is not routinely performed. we investigated bartonella spp. prevalence in 500 blood donors from campinas, brazil, based on a cro ...	2015	25590435
prevalence of select vector-borne pathogens in stray and client-owned dogs from algiers.	data on the prevalence of vector-borne diseases agents infecting canines in algeria is currently lacking. the purpose of this study is to assess by serological and molecular methods the prevalence of select arthropod borne-bacterial infections in client-owned and stray dogs. antibodies to anaplasma phagocytophilum were the most prevalent at 47.7%, followed by borrelia burgdorferi s.l. at 37.6%, ehrlichia canis at 30.0%, bartonella henselae at 32.4% and bartonella vinsonii subsp. berkhoffii at 27 ...	2015	25638478
underrecognized arthropod-borne and zoonotic pathogens in northern and northwestern thailand: serological evidence and opportunities for awareness.	although scrub typhus and murine typhus are well-described tropical rickettsial illnesses, especially in southeast asia, only limited evidence is available for rickettsia-like pathogens contributing to the burden of undifferentiated febrile illness. using commercially available kits, this study measured immunoglobulin g (igg) antibody seroprevalence for coxiella burnetii, ehrlichia chaffeensis, bartonella henselae, anaplasma phagocytophilum, and spotted fever group rickettsiae (sfgr) in 375 pati ...	2015	25988437
molecular survey of arthropod-borne pathogens in ticks obtained from japanese wildcats.	the iriomote cat (ic), prionailurus bengalensis iriomotensis, and the tsushima leopard cat (tlc), prionailurus bengalensis euptilurus, are endangered subspecies of leopard cats in japan. in addition to habitat destruction and road kills, infectious diseases may threaten their populations, and infection with arthropod-borne pathogens has been reported in both subspecies. infestations with ectoparasites, especially ticks, have frequently been observed in ics and tlcs. in the present study, ticks c ...	2015	25682495
the significance of bartonella henselae bacterias for oncological diagnosis in children.	cat-scratch disease (csd) is a common infection in children; however, the wide spectrum of its clinical picture may lead to delayed diagnosis. an unusual presentation of csd includes in the differential diagnosis malignant diseases, epstein-barr and cytomegalovirus infections, tuberculosis, and mycobacterioses. the diagnostic procedure is difficult, and it is important to consider csd as the etiology of untypical lesion.	2015	26379764
cat-scratch disease: a wide spectrum of clinical pictures.	the aim of this review is to present an emerging zoonotic disease caused by bartonella henselae. the wide spectrum of diseases connected with these bacteria varies from asymptomatic cases, to skin inflammation, fever of unknown origin, lymphadenopathy, eye disorders, encephalitis and endocarditis. the reservoirs of b. henselae are domestic animals like cats, guinea pigs, rabbits and occasionally dogs. diagnosis is most often based on a history of exposure to cats and a serologic test with high t ...	2015	26161064
did bartonella henselae contribute to the deaths of two veterinarians?	bartonella henselae, a flea-transmitted bacterium, causes chronic, zoonotic, blood stream infections in immunocompetent and immunocompromised patients throughout the world. as an intra-erythrocytic and endotheliotropic bacterium, b. henselae causes a spectrum of symptomatology ranging from asymptomatic bacteremia to fever, endocarditis and death. veterinary workers are at occupational risk for acquiring bartonellosis. as an emerging, and incompletely understood, stealth bacterial pathogen, b. he ...	2015	26062543
infectious causes of encephalitis and meningoencephalitis in thailand, 2003-2005.	acute encephalitis is a severe neurologic syndrome. determining etiology from among ≈100 possible agents is difficult. to identify infectious etiologies of encephalitis in thailand, we conducted surveillance in 7 hospitals during july 2003-august 2005 and selected patients with acute onset of brain dysfunction with fever or hypothermia and with abnormalities seen on neuroimages or electroencephalograms or with cerebrospinal fluid pleocytosis. blood and cerebrospinal fluid were tested for >30 pat ...	2015	25627940
inhibition of the endosymbiont "candidatus midichloria mitochondrii" during 16s rrna gene profiling reveals potential pathogens in ixodes ticks from australia.	the australian paralysis tick (ixodes holocyclus) is of significant medical and veterinary importance as a cause of dermatological and neurological disease, yet there is currently limited information about the bacterial communities harboured by these ticks and the risk of infectious disease transmission to humans and domestic animals. ongoing controversy about the presence of borrelia burgdorferi sensu lato (the aetiological agent of lyme disease) in australia increases the need to accurately id ...	2015	26108374
necrotizing anca-positive glomerulonephritis secondary to culture-negative endocarditis.	infective endocarditis (ie) and small-vessel vasculitis may have similar clinical features, including glomerulonephritis. furthermore the association between ie and anca positivity is well documented, making differential diagnosis between ie- and anca-associated vasculitis particularly difficult, especially in case of culture-negative ie. we report on one patient with glomerulonephritis secondary to culture-negative ie caused by bartonella henselae which illustrates this diagnostic difficulty.	2015	26819786
[bartonella henselae infection revealed by guillain barre syndrome].		2015	26757509
coexistence of bartonella henselae and b. clarridgeiae in populations of cats and their fleas in guatemala.	cats and their fleas collected in guatemala were investigated for the presence of bartonella infections. bartonella bacteria were cultured from 8.2% (13/159) of cats, and all cultures were identified as b. henselae. molecular analysis allowed detection of bartonella dna in 33.8% (48/142) of cats and in 22.4% (34/152) of cat fleas using glta, nuog, and 16s-23s internal transcribed spacer targets. two bartonella species, b. henselae and b. clarridgeiae, were identified in cats and cat fleas by mol ...	2015	26611968
prevalence of rickettsia and bartonella species in spanish cats and their fleas.	the aim of this study was to determine the prevalence of bartonella henselae, rickettsia felis, and rickettsia typhi in fleas and companion cats (serum and claws) and to assess their presence as a function of host, host habitat, and level of parasitism. eighty-nine serum and claw samples and 90 flea pools were collected. cat sera were assayed by ifa for bartonella henselae and rickettssia species igg antibodies. conventional pcrs were performed on dna extracted from nails and fleas collected fro ...	2015	26611956
bartonella henselae infection caused by cat flea bite.		2015	26564808
posterior segment involvement in cat-scratch disease: a case series.	cat-scratch disease (csd) is a systemic infectious disease. the most well-known posterior segment presentation is neuroretinitis with a macular star. in this study, we present a case series emphasising the heterogeneity of the disease and the various posterior segment manifestations.	2015	26545331
neuroretinitis with dual infections.	a 22-year-old malay female presented with left eye floaters for 2 weeks, associated with temporal visual field defect and metamorphopsia for 3 days. she has a guinea pig and a hedgehog at home, but denied being bitten or scratched by them. her visual acuity at presentation was 6/12 on the left eye and 6/6 on the right eye. her left eye relative afferent pupillary defect was barely positive with mild anterior chamber reaction. fundus examination of the left eye showed mild vitritis, swollen optic ...	2015	26527902
concomitant pasteurella multocida aortic endograft infection and bartonella henselae endocarditis.		2015	26472059
impact of queen infection on kitten susceptibility to different strains of bartonella henselae.	domestic cats are the natural reservoir of bartonella henselae, the agent of cat scratch disease in humans. in kittens, maternal igg antibodies are detectable within two weeks postpartum, weaning in six to ten weeks postpartum and kittens as young as six to eight weeks old can become bacteremic in a natural environment. the study's objective was to evaluate if maternal antibodies against a specific b. henselae strain protect kittens from infection with the same strain or a different strain from ...	2015	26454564
progressive cat scratch disease despite antimicrobial therapy.		2015	26407443
fever and renal failure in a child with digeorge syndrome and tetralogy of fallot.		2015	26407263
molecular detection of bartonella species in fleas collected from dogs and cats from costa rica.	the bacterial genus bartonella includes several species with zoonotic potential, some of which are common in domestic dogs and cats, as well as in their fleas. because there is no previous information about the presence of bartonella species in fleas from central america, this study aimed at evaluating the presence of bartonella spp. in fleas collected from dogs and cats in costa rica. a total 72 pools of ctenocephalides felis and 21 pools of pulex simulans were screened by conventional pcr to d ...	2015	26393956
cat-scratch disease: case report and review of the literature.	cat-scratch disease (csd) is caused by bartonella henselae and characterized by self-limited fever and granulomatous lymphadenopathy. in some cases signs of a visceral, neurologic, and ocular involvement can also be encountered. in this report we describe the development of csd in a kidney transplant patient. immunocompromised hosts are more susceptible to infection from bartonella compared with the standard population. infection of bartonella should be considered as a differential diagnosis in ...	2015	26361690
a case of atypical bartonella henselae infection in a patient with methimazole-induced agranulocytosis.	antithyroid medications such as methimazole and propylthiouracil are commonly used to treat hyperthyroid disorders. thionamide-induced agranulocytosis is a rare but life-threatening potential side effect of these medicines. in addition to routine monitoring of blood counts, healthcare workers caring for patients on such medication need to be mindful of atypical presentations of acute agranulocytosis throughout the treatment course. the manifestations of underlying infectious aetiologies can be m ...	2015	26315358
the etiology of juvenile idiopathic arthritis.	over the years, the commonly used term to describe juvenile idiopathic arthritis (jia) has changed. by definition, jia includes all types of arthritis with no apparent cause, lasting more than 6 weeks, in patients aged less than 16 years at onset. jia pathogenesis is still poorly understood: the interaction between environmental factors and multiple genes has been proposed as the most relevant working mechanism to the development of jia. the concept that various microbes that colonize or infect ...	2015	25384710
the efficacy of a selamectin (stronghold ®) spot on treatment in the prevention of bartonella henselae transmission by ctenocephalides felis in cats, using a new high-challenge model.	bartonella henselae is the causative agent of cat scratch disease in humans, which is recognized as an emerging zoonotic disease. ctenocephalides felis is the main vector, and transmission of b. henselae infection between cats and humans occurs mainly through infected flea feces. control of feline infestation with this arthropod vector therefore provides an important strategy for the prevention of infection of both humans and cats. in the present study, a new challenge model is used to evaluate ...	2015	25582566
a 31-year-old man with bilateral blurry vision and floaters.	we report a case of bilateral multifocal retinochoroiditis and bilateral optic disc edema in a patient with cat-scratch disease from bartonella henselae. the patient initially had negative serologic testing. repeat testing showed a markedly increased igg and igm convalescent titer and the development of a branch retinal artery and vein occlusion. in patients for whom there is a high clinical suspicion of cat-scratch disease, a convalescent titer should be obtained 2-3 weeks following a negative ...	2015	27330461
rickettsial diseases and ectoparasites from military bases in japan.	ectoparasitic arthropods are often vectors of rickettsiosis. we conducted a survey of ectoparasites on u.s. military facilities throughout japan with the use of specimens submitted by pest control, public health, and veterinary personnel. over 1,600 individual ectoparasites were collected. fifteen species were identified, including several significant vectors of human diseases such as scrub typhus and rickettsial spotted fevers. these ectoparasites included ctenocephalides felis , haemaphysalis ...	2015	25548900
neuroretinitis secondary to bartonella henselae in the emergent setting.		2015	25497596
vector-borne pathogens in arctic foxes, vulpes lagopus, from canada.	because of the relatively low biodiversity within arctic ecosystems, arctic foxes, vulpes lagopus, could serve as sentinels for the study of changes in the ecology of vector-borne zoonotic pathogens. the objective of this study was to determine the molecular prevalence of 5 different genera of vector borne pathogens (anaplasma, babesia, bartonella, ehrlichia, and hemotropic mycoplasma spp.) using blood collected from 28 live-trapped arctic foxes from the region of karrak lake, nunavut, canada. b ...	2015	25596149
update and commentary on four emerging tick-borne infections: ehrlichia muris-like agent, borrelia miyamotoi, deer tick virus, heartland virus, and whether ticks play a role in transmission of bartonella henselae.	emerging tick-borne infections continue to be observed in the united states and elsewhere. current information on the epidemiology, clinical and laboratory features, and treatment of infections due to ehrlichia muris-like agent, deer tick virus, borrelia miyamotoi sensu lato, and heartland virus was provided and critically reviewed. more research is needed to define the incidence and to understand the clinical and the laboratory features of these infections. there is also a growing need for the ...	2015	25999230
reprogramming of myeloid angiogenic cells by bartonella henselae leads to microenvironmental regulation of pathological angiogenesis.	the contribution of myeloid cells to tumour microenvironments is a decisive factor in cancer progression. tumour-associated macrophages (tams) mediate tumour invasion and angiogenesis through matrix remodelling, immune modulation and release of pro-angiogenic cytokines. nothing is known about how pathogenic bacteria affect myeloid cells in these processes. here we show that bartonella henselae, a bacterial pathogen causing vasculoproliferative diseases (bacillary angiomatosis), reprogrammes huma ...	2015	25857345
cat-scratch disease presenting as a solitary splenic abscess in an elderly man.	patients with cat-scratch disease (csd), which is caused by bartonella henselae, typically present with local lymphadenopathy with a brief period of fever and general symptoms. most cases are self-limiting and usually afflict children and young adults. although rare, csd can lead to serious complications, especially in immunocompromised patients. these rare complications often require intensive treatment. we describe the case of a 79-year-old man who presented with general malaise and a high fev ...	2015	25804947
bartonella henselae infection-associated vasculitis and crescentic glomerulonephritis leading to renal allograft loss.	bartonella henselae (bh) is the main cause of cat scratch disease (csd), which more typically presents as a self-limited localized suppurative lymphadenopathy in immunocompetent individuals. in contrast, immunocompromised patients commonly have systemic disease with life-threatening complications. in addition to the angioproliferative lesions, such as bacillary angiomatosis, an increasing number of immune post-infectious complications are being recognized with bh infections, including glomerulon ...	2015	25753276
infection with bartonella henselae in a danish family.	bartonella species constitute emerging, vector-borne, intravascular pathogens that produce long-lasting bacteremia in reservoir-adapted (natural host or passive carrier of a microorganism) and opportunistic hosts. with the advent of more sensitive and specific diagnostic tests, there is evolving microbiological evidence supporting concurrent infection with one or more bartonella spp. in more than one family member; however, the mode(s) of transmission to or among family members remains unclear. ...	2015	25740763
prevalence of bartonella spp. in canine cutaneous histiocytoma.	canine cutaneous histiocytoma (cch) is a common, benign neoplastic proliferation of histiocytes of langerhans cell origin that often ulcerate, become secondarily infected and regress spontaneously. bartonella is a fastidious genus of facultative intracellular pathogens that can be transmitted through arthropod bites and epidermal animal scratches and has been identified previously in the cytoplasm of histiocytes within granulomatous lesions and in skin biopsy samples of inflammatory pustules and ...	2015	25980841
persistent cat scratch disease requiring surgical excision in a patient with mpgn.	we present the case of a 13-year-old immunosuppressed patient with unrelenting cat scratch disease despite 9 months of antibiotic therapy. the patient was being treated with mycophenolate and prednisone for membranoproliferative glomerulonephritis (type 1) diagnosed 13 months before the onset of cat scratch disease. cat scratch disease was suspected due to epitrochlear lymphadenitis and an inoculation papule on the ipsilateral thumb, and the diagnosis was confirmed by the use of acute and conval ...	2015	25963015
bartonella osteomyelitis of the acetabulum: case report and review of the literature.	bartonella henselae commonly involves the mononuclear phagocyte system (mps), and its most common presentation is lymphadenitis. rarely, it can cause isolated osteomyelitis. we present a case of a 3 year old with constitutional symptoms and new onset of limp. previously reported cases of osteomyelitis due to b. henselae are also reviewed here, keeping the index case in mind.	2015	26273806
bartonella henselae osteoarthritis of the upper cervical spine in a 14-year-old boy.	we report a case of bartonella henselae, an agent of cat scratch disease, c1-c2 osteoarthritis with osteolysis of the lateral mass of c2 in a 14-year-old boy. oral antibiotics did not successfully treat the infection and surgery was necessary to treat the septic arthritis. the case opens discussion about bacterial osteoarthritis of the cervical spine and bone involvement in disseminated bartonellosis.	2015	25881557
clinicocytopathologic correlation in an atypical presentation of lymphadenopathy with review of literature.	to present a clinicocytopathologic correlation of an atypical case of cat scratch disease (csd) involving retroperitoneal lymph nodes, with emphasis on communication between service teams for managing lymphadenopathy of unknown origin. we consider clinical and cytologic differential diagnoses and review the literature on atypical cases of csd, with emphasis on abdominal presentation and cytologic findings.	2015	25873511
pediatric cervicofacial lymphadenitis caused by bartonella henselae.	chronic cervicofacial lymphadenitis in children is often caused by nontuberculous mycobacterium or bartonella henselae species (known as cat scratch disease).	2015	26254984
infective endocarditis with negative blood culture and negative echocardiographic findings.	a 61-year-old male presented with fever. he had a history of aortic valve replacement, and infective endocarditis was suspected. the transthoracic and transesophageal echocardiography on admission could not detect vegetation, and all blood cultures obtained were negative. we concluded that infective endocarditis was not likely. however, repeated echocardiography revealed paravalvular regurgitation and paravalvular abscess. serum antibody testing for bartonella henselae was positive, leading to t ...	2015	26184640
hepatosplenic cat-scratch disease in children and the positive contribution of 18f-fdg imaging.	two patients were referred to our hospital because of suspected malignancy. in patient 1, a 4-year-old boy, a f-fdg pet scan showed an enlarged liver with multiple fdg-positive nodular lesions. in patient 2, a 16-year-old boy, a fdg pet-(low-dose) ct showed an enlarged liver and spleen with multiple nodular lesions and a solitary hypodense nodule adjacent to the pancreatic head. the lesions were thought to originate from infectious disease or lymphoma. polymeric chain reaction (pcr) on a liver b ...	2015	26164171
bartonella infection among cats adopted from a san francisco shelter, revisited.	bartonella infection among cats from shelters can pose a health risk to adopters. bartonella henselae is the most common species, with b. clarridgeiae and b. koehlerae being less common. the lower rates of infection by the latter species may reflect their rarity or an inefficiency of culture techniques. to assess the incidence of infection, blood cultures, serology, and pcr testing were performed on 193 kittens (6 to 17 weeks old) and 158 young adult cats (5 to 12 months old) from a modern regio ...	2015	26162871
ocular bartonellosis in transplant recipients: two case reports and review of the literature.	cat scratch disease is caused by bartonella henselae and usually manifests as localized lymphadenopathy and fever in immunocompetent patients. immunocompromised patients are at risk for developing disseminated disease affecting the liver, spleen, eyes, central nervous system, and other organs. bartonellosis is infrequently reported in solid organ transplant recipients, and published case reports usually discuss disseminated infection. localized ocular disease with b. henselae, while well documen ...	2015	26146758
choroidal neovascularisation as an unusual ophthalmic manifestation of cat-scratch disease in an 8-year-old girl.	to report the first case of choroidal neovascularisation (cnv) that appeared during the primary bartonella henselae infection in an 8-year-old girl. an 8-year-old girl was referred to our clinic complaining of a central scotoma in the right eye. fundus examination revealed a bilateral disc oedema and in the right eye neuroretinitis with macular star and cnv, which was confirmed by fluorescein angiography. the optical coherence tomography revealed the presence of macular serous retinal detachment ...	2015	26135983
[incidence of bartonella henselae infection during the period 2009-2012 in the valencian community, spain].	bartonella henselae is the causative agent of the disease caused by cat scratches and it has a worldwide distribution. the objective of the study was to investigate its incidence in the valencian community during the period 2009-2012.	2015	26121631
cat-scratch disease with severe pleuritis in a 6-year-old girl.	we present the case of a 6-year-old girl with cat-scratch disease (csd), who developed severe pleuritis without lymphadenitis. bartonella henselae dna was detected on real-time polymerase chain reaction (pcr) analysis of whole blood. this is the first report of csd diagnosed on real-time pcr using whole blood.	2015	26113319
a challenging differential diagnosis of optic neuropathy in ed: csd.	optic neuropathy due to cat scratch disease (csd) is a rare occurrence associated with macular star formation and is characterised by sudden mostly unilateral painless loss of vision. the aetiological agent in csd is bartonella henselae. ocular complications present in up to 10% of patients and include neuroretinitis, conjunctivitis or uveitis. ocular bartonelosis is usually self-limited. a case of a man patient with neuroretinitis caused by b. henselae is reported.	2015	26077806
infections and cardiovascular disease: is bartonella henselae contributing to this matter?	cardiovascular disease is still the major cause of death worldwide despite the remarkable progress in its prevention and treatment. endothelial progenitor cells (epcs) have recently emerged as key players of vascular repair and regenerative medicine applied to cardiovascular disease. a large amount of effort has been put into discovering the factors that could aid or impair the number and function of epcs, and also into characterizing these cells at the molecular level in order to facilitate the ...	2015	26066633
seroprevalence of bartonella henselae in patients awaiting heart transplant in southern italy.	bartonella henselae is the etiologic agent of cat-scratch disease. b. henselae infections are responsible for a widening spectrum of human diseases, although often symptomless, ranging from self-limited to life-threatening and show different courses and organ involvement due to the balance between host and pathogen. the role of the host immune response to b. henselae is critical in preventing progression to systemic disease. indeed in immunocompromised patients, such as solid organ transplant pa ...	2015	26051222
bartonella henselae in eastern poland: the relationship between tick infection rates and the serological response of individuals occupationally exposed to tick bites.	to explore the potential role of ixodes ricinus as the presumed vector of bartonella henselae in eastern poland, ticks collected in various geographic locations were examined for the presence of b. henselae, and the results were matched against the prevalence of anti-b. henselae antibodies in individuals occupationally exposed to tick bites. the presence of bartonella dna was investigated by pcr in a total of 1,603 unfed ixodes ricinus ticks. the presence of igg antibodies against b. henselae wa ...	2015	26047187
new-onset refractory status epilepticus in an adult with an atypical presentation of cat-scratch disease: successful treatment with high-dose corticosteroids.	new-onset refractory status epilepticus (norse) is defined as a sudden onset of refractory status epilepticus in patients who do not have a history of epilepsy. it is a neurologic emergency, and determining the underlying etiology is an important factor for effectively managing and predicting the prognosis of norse. we describe the case of a 28-year-old woman who was hospitalized with norse secondary to an unknown etiology. she did not respond to traditional anticonvulsant therapy, including ben ...	2015	26044784
[diagnosis of infectious lymphadenitis].	adenitis is a common disorder requesting numerous medical specialties. etiologies are dominated by viral and bacterial infections, and more rarely parasitic, or by neoplastic and inflammatory diseases. nevertheless, etiology remains often unknown and invasive tests may be required. on nodal tissue sample, histological examination, culture and polymerase chain reaction (pcr) are realized. pcr has revolutionized the diagnostic approach and consequently, knowledge of infectious lymphadenopathy. pre ...	2015	26021493
bartonella henselae endocarditis and glomerulonephritis with dominant c3 deposition in a 21-year-old male with a melody transcatheter pulmonary valve: case report and review of the literature.	we report a case of a 21-year-old young man with underlying congenital heart disease who developed bartonella henselae endocarditis of the right ventricular outflow tract (rvot) conduit of his melody transcatheter (percutaneous) pulmonary valve (tpv), with an initial presentation of glomerulonephritis with a dominant c3 pattern, with renal failure and circulating cryoglobulins. there are few reports of a glomerulonephritis with a dominant c3 pattern presenting as a manifestation of b. henselae e ...	2015	24896298
molecular identification of bartonella henselae in a seronegative cat scratch disease patient with aids in rio de janeiro, brazil.	bartonella henselae is associated with a wide spectrum of clinical manifestations, including cat scratch disease, endocarditis and meningoencephalitis, in immunocompetent and immunocompromised patients. we report the first molecularly confirmed case of b. henselae infection in an aids patient in state of rio de janeiro, brazil. although dna sequence of b. henselae has been detected by polymerase chain reaction in a lymph node biopsy, acute and convalescent sera were nonreactive.	2015	25076441
concurrent bartonella henselae infection in a dog with panniculitis and owner with ulcerated nodular skin lesions.	bartonella henselae, a gram-negative, zoonotic alphaproteobacteria that infects erythrocytes, endothelial cells and dendritic cells, has previously been implicated as a cause of panniculitis in dogs and a human.	2015	25292107
[disseminated infection due to bartonella henselae in a kidney transplant recipient].		2015	25665525
intra-nodal injection of gentamicin for the treatment of suppurated cat scratch disease's lymphadenitis.	cat scratch disease (csd)'s lymphadenitis may have a protracted course with painful suppuration necessitating several needle aspirations or surgical drainage. the objective of this study was to evaluate the benefit of an intra-nodal injection of gentamicin add-on oral azithromycin treatment on the outcome of suppurated csd's lymphadenitis.	2016	26001741
[an exceptional case of tricuspid infective endocarditis due to bartonella henseale revealed by an old pulmonary embolism].	we report a case of blood culture-negative tricuspid infective endocarditis revealed after tick bite by repeated pulmonary infection during one year due to septic pulmonary emboli in a 67-year-old farmer woman. tricuspid vegetation and pulmonary emboli are calcified. lyme serology is negative. serologic test and pcr analysis are positive to bartonella henselae. the evolution is favorable after antibiotic and anticoagulant treatment. infective endocarditis due to b. henselae is an exceptional com ...	2016	25869466
field comparison of tolerance of a collar containing 10.0% imidacloprid/4.5% flumethrin (seresto) and a placebo collar placed on cats.	a collar containing 10.0% imidacloprid/4.5% flumethrin (seresto; bayer animal health) controls flea and tick infestations for 8 months and is effective in preventing transmission of bartonella henselae and cytauxzoon felis among cats. the purpose of this study was to compare tolerance of client-owned cats for the 10.0% imidacloprid/4.5% flumethrin collar or a physically identical placebo collar.	2016	26269454
disseminated cat-scratch disease: case report and review of the literature.	cat scratch disease (csd) can present as a systemic disease in 5-10% of cases and lead to various disease entities. a previously healthy 16-month-old boy presented with fever for 7 days without other obvious symptoms. abdominal computed tomography scan demonstrated enlarged right inguinal lymph nodes and multiple small round hypodensities in the spleen. despite antibiotic treatment for 1 week, the fever persisted and the intrasplenic lesions progressed. inguinal lymph node biopsy confirmed csd b ...	2016	25940800
an 8-year-old boy with altered mental status.	management of an acutely ill pediatric patient with undifferentiated altered mental status is a common challenge facing air medical crewmembers. the transport team is often the vital link between the referring agency and a tertiary care center; it is incumbent upon the team to be able to meet the challenges of patient management including airway management, providing hemodynamic support, and addressing presenting symptoms. this case presents a child with altered mental status and seizure activit ...	2016	25934240
cat scratch disease in kidney transplant receptors: is it a rare or underdiagnosed pathology?	cat scratch disease (csd) is an infectious disorder which appears after cat scratching particularly in children and adolescents. bartonella henselae is the etiologic agent more frequently involved. there are only a few recent reports demonstrating the disease after transplantation, although the illness is not infrequent in immunologically competent people. indeed csd in transplant receptors has only been recently emphasized in the literature and it was concluded that fever and lymphadenopathy in ...	2016	25317626
splenic vasculitis, thrombosis, and infarction in a febrile dog infected with bartonella henselae.	to describe the clinical course and successful management of a febrile dog with polyarthritis, splenic vasculitis, thrombosis, and infarction that was infected with bartonella henselae.	2016	26308573
broadening the morphologic spectrum of bartonella henselae lymphadenitis: analysis of 100 molecularly characterized cases.	bartonella henselae lymphadenitis, or cat-scratch lymphadenitis (csl), is classically associated with stellate microabscesses, occasional giant cells, and extension of the inflammatory infiltrate into perinodal soft tissue. availability of b. henselae molecular testing on tissue specimens has broadened our understanding of the morphologic variation in this disease. here we sought to describe the histopathologic features of the largest series to date of molecularly proven csl. b. henselae polymer ...	2016	26551620
multiple renal and splenic lesions in cat scratch disease.	cat scratch disease (csd) is an infectious disease caused by bartonella henselae. atypical clinical presentations of csd include prolonged fever and multiple hepatosplenic lesions. furthermore, multiple renal lesions are extremely rare in csd. an 11-year-old japanese girl presented at our hospital with a prolonged fever of unknown cause after being scratched and bitten by a kitten. abdominal computed tomography (ct) revealed multiple small, round hypodense lesions in both kidneys and the spleen. ...	2016	26567841
isolation of bartonella henselae and two new bartonella subspecies, bartonellakoehlerae subspecies boulouisii subsp. nov. and bartonella koehlerae subspecies bothieri subsp. nov. from free-ranging californian mountain lions and bobcats.	domestic cats are the natural reservoir of bartonella henselae, b. clarridgeiae and b. koehlerae. to determine the role of wild felids in the epidemiology of bartonella infections, blood was collected from 14 free-ranging california mountain lions (puma concolor) and 19 bobcats (lynx rufus). bartonella spp. were isolated from four (29%) mountain lions and seven (37%) bobcats. these isolates were characterized using growth characteristics, biochemical reactions, molecular techniques, including pc ...	2016	26981874
absence of serological evidence of rickettsia spp., bartonella spp., ehrlichia spp. and coxiella burnetii infections in american samoa.	little is known about the epidemiology of zoonotic diseases in american samoa (pacific). a review of literature did not identify any published information on human rickettsia spp., bartonella spp., ehrlichia spp. or coxiella burnetii infections in this country. to determine the presence of these diseases, we conducted a serosurvey of american samoans. the presence of immunoglobulin g antibodies against rickettsia felis, rickettsia typhi, rickettsia conorii, c. burnetii, bartonella henselae, bart ...	2016	26965788
bartonella species identified in rodent and feline hosts from island and mainland western australia.	bacteria of the genus bartonella have been described in multiple mammalian hosts with many species capable of causing disease in humans. cats and various species of rats have been reported to play a role as vertebrate hosts to a number of bartonella spp. this study aimed to identify bartonella spp. in western australia, dirk hartog island (dhi), and christmas island (ci) and to investigate the presence of potential arthropod vectors. feral cats were collected from ci (n = 35), dhi (n = 23) and s ...	2016	26900749
[eye and cat scratch disease: a case series].	cat scratch disease is a pleiomorphic condition, sometimes with isolated ophthalmic involvement. we report the clinical observations of seven cases with ophthalmologic manifestations of cat scratch disease.	2016	26868534
development of a highly specific igm enzyme-linked immunosorbent assay for bartonella henselae using refined n-lauroyl-sarcosine-insoluble proteins for serodiagnosis of cat scratch disease.	the conventional anti-bartonella henselaeigm enzyme-linked immunosorbent assay (igm-elisa) methods for diagnosing cat scratch disease (csd) remain poor in both sensitivity and specificity. we sought to develop an igm-elisa with improved accuracy in the serodiagnosis of csd by exploring the antigens that are most suitable for an elisa. we prepared 5 different protein antigens: antigen i (sonicatedb. henselaewhole-cell antigen), antigen ii (n-lauroyl-sarcosine-insoluble antigen), antigen iii (proc ...	2016	26865692
retinal artery occlusion due to bartonella henselae infection: a case series.	to report a case series of six patients suffering from branch retinal artery occlusion due to bartonella henselae infection, in order to raise awareness to this etiology in the differential diagnosis of retinal artery occlusion.	2016	26748767
cat scratches, not bites, are associated with unipolar depression--cross-sectional study.	a recent study performed on 1.3 million patients showed a strong association between being bitten by a cat and probability of being diagnosed with depression. authors suggested that infection with cat parasite toxoplasma could be the reason for this association.	2016	26728406
[osteomyelitis in cat scratch disease: a case report and literature review].	cat scratch disease is an infection caused by bartonella henselae. the main clinical form is a lymphadenopathy with fever. however, uncommon bone involvement has been described.	2016	26727156
characterization of the general stress response in bartonella henselae.	bacteria utilize a general stress response system to combat stresses from their surrounding environments. in alpha-proteobacteria, the general stress response uses an alternate sigma factor as the main regulator and incorporates it with a two-component system into a unique regulatory circuit. this system has been described in several alpha-proteobacterial species, including the pathogens bartonella quintana and brucella abortus. most of the studies have focused on characterizing the phyr anti-an ...	2016	26724735
[neuroretinitis with stellate macular edema and papilledema: bartonella henselae infection (cat-scratch disease)].		2016	26709149
melody valve bartonella henselae endocarditis in an afebrile teen: a case report.	significant advancements in the care of children with cardiac valve disease over the past 15 years have led to the increasingly common use of percutaneous transcatheter valve implantation as an alternative to surgical replacement in selected patient populations. although the transcatheter approach has several advantages, this approach and the valves used are not without complications. bacterial endocarditis is a known and concerning complication after transcatheter pulmonary valve replacement (t ...	2016	26659816
hemophagocytic lymphohistiocytosis associated with bartonella henselae infection in an hiv-infected patient.	hemophagocytic lymphohistiocytosis (hlh) is a life-threatening syndrome that often occurs in immunocompromised patients. we report the first case of hlh due to bartonella henselae infection in a patient with human immunodeficiency virus infection. early recognition of hlh and b. henselae through liver biopsy and serological tests led to the patient's recovery.	2016	26646679
identification and functional analysis of invasion associated locus b (ialb) in bartonella species.	bartonellosis is caused by the genus bartonella. bartonella is widely distributed in the ruminants, cats, dogs, rodents and other mammals including humans. at least 13 species or subspecies of bartonella are zoonotic, and each species appears to be highly adapted to one or a limited number of reservoir animals in which it is asymptomatic, while it can be transmitted to humans in which a variety of clinical manifestations can be caused. it was reported that bartonella henselae infection rate amon ...	2016	27515099
isolation of bartonella henselae, bartonella koehlerae subsp. koehlerae, bartonella koehlerae subsp. bothieri and a new subspecies of b. koehlerae from free-ranging lions (panthera leo) from south africa, cheetahs (acinonyx jubatus) from namibia and captive cheetahs from california.	bartonellae are blood- and vector-borne gram-negative bacteria, recognized as emerging pathogens. whole-blood samples were collected from 58 free-ranging lions (panthera leo) in south africa and 17 cheetahs (acinonyx jubatus) from namibia. blood samples were also collected from 11 cheetahs (more than once for some of them) at the san diego wildlife safari park. bacteria were isolated from the blood of three (5%) lions, one (6%) namibian cheetah and eight (73%) cheetahs from california. the lion ...	2016	27453220
similar presentation of cervical lymphadenitis of different etiology in two siblings.	here, we report chronic suppurating submandibular swelling occurring in two siblings, with one case caused by nontuberculous mycobacteria and the other caused by bartonella henselae. these two infections share a similar clinical presentation, but the treatment modalities differed.	2016	27422429
development of fluorogenic probe-based and high-resolution melting-based polymerase chain reaction assays for the detection and differentiation of bartonella quintana and bartonella henselae.	bartonella henselae and bartonella quintana are the major etiological agents of infective endocarditis, which pose a serious threat to human health. to simultaneously detect and differentiate b. henselae and b. quintana, a reliable and fast method to simultaneously detect and differentiate b. henselae and b. quintana is required. in this study, we developed and validated two rapid, highly sensitive and specific, duplex, real-time polymerase chain reaction (pcr) assays-one based on high-resolutio ...	2016	27316654
encephalitis with convulsive status in an immunocompetent pediatric patient caused by bartonella henselae.	cat scratch's disease caused by bartonella henselae, is known to be a self-limited benign process in immunocompetent children. the association with neurologic manifestations is very uncommon especially in patient with no immunologic defects and in cases without specific treatment. a 7 years old male patient, without any immunocompromised defect, presented an atypic presentation of the cat scratch disease. the patient came to the hospital in two opportunities in a status epilepticus, in both case ...	2016	27262077
suggested relationship between hemophagocytic lymphohistiocytosis and bartonella henselae.		2016	27161780
vasculitis, cerebral infarction and persistent bartonella henselae infection in a child.	the genus bartonella is comprised of a rapidly increasing number of pathogenic species that induce a seemingly diverse spectrum of neurological symptoms. during the 12 year period that followed the initial onset of neurological and gastrointestinal symptoms, an 11 year-old girl experienced a spectrum of neurological complaints including frequent headaches, visual and auditory hallucinations, anxiety, vision loss involving the lower left quadrant of both eyes, episodic bouts of generalized paraly ...	2016	27161220
[molecular epidemiology of bartonella henselae in stray and sheltered cats of zaragoza, spain].	bartonella henselae is responsible for the cat scratch disease in humans, being it underdiagnosed. this study aims to detect and quantify the load of b. henselae dna in oral and whole blood samples from stray and shelthered cats from zaragoza (spain), and analyze associations with epidemiological and clinical factors.	2016	27145996
splenorenal manifestations of bartonella henselae infection in a pediatric patient.	bartonella henselae is a bacterium which can cause a wide range of clinical manifestations, ranging from fever of unknown origin to a potentially fatal endocarditis. we report a case of bartonella henselae infection in a pediatric-aged patient following a scratch from a kitten. the patient initially presented with a prolonged fever of unknown origin which was unresponsive to antibiotic treatment. the patient was hospitalized with worsening fevers and night sweat. subsequent ultrasound imaging de ...	2016	27127672
disseminated cat-scratch disease: case report and review of the literature.	cat scratch disease (csd) can present as a systemic disease in 5-10% of cases and lead to various disease entities. a previously healthy 16-month-old boy presented with fever for 7 days without other obvious symptoms. abdominal computed tomography scan demonstrated enlarged right inguinal lymph nodes and multiple small round hypodensities in the spleen. despite antibiotic treatment for 1 week, the fever persisted and the intrasplenic lesions progressed. inguinal lymph node biopsy confirmed csd b ...	2016	27077606
cat-scratch disease with hepatosplenic lesions in two brothers.		2016	27051576
prevalence of leishmania infantum and co-infections in stray cats in northern italy.	stray cats in the city of milan, italy, were tested for leishmania infantum and other selected infections. twenty-seven cats (30.0%) were seroreactive by indirect fluorescent antibody test (ifat), with an antibody titer of 1:40 for 16 (17.7%) cats and 1:80 (cut-off for feline l. infantum infection) for 11 (12.2%) cats. one blood (1.1%) and one popliteal lymph node (1.1%) sample tested positive by real-time polymerase chain reaction; no oculoconjunctival swabs tested positive. feline immunodefici ...	2016	27012922
bartonella henselae in italy: a rare seasonal infection.	symptomatic bartonella henselae infection is considered rare in europe. cat fleas transmit the microorganism between cats, but their role in transmission of b. henselae to humans has not been defined. the aim of our study was to perform a retrospective study of detected cases at our hospital.	2016	27008366
bartonella henselae infection presenting with a picture of adult-onset still's disease.	we report a patient with a clinical picture of suggestive for adult-onset still's disease (asod) due to bartonella infection. a 42-year-old immunocompetent man was admitted with fever, rash, arthralgia and sore throat. as his clinical picture suggested asod except unusual skin manifestation, we treated him on steroid and ibuprofen. his fever and constitutional symptoms responded immediately within 24hrs of commencing therapy, yet rash and leukocytosis remained. meanwhile, bartonella infection wa ...	2016	27000538
culture, pcr, dna sequencing, and second harmonic generation (shg) visualization of bartonella henselae from a surgically excised human femoral head.		2016	28028681
multi-organ involvement confounding the diagnosis of bartonella henselae infective endocarditis in children with congenital heart disease.	two children with congenital heart disease status-post surgical correction presented with prolonged constitutional symptoms, hepatosplenomegaly and pancytopenia. concern for malignancy prompted bone marrow biopsies that were without evidence thereof. in case #1, echocardiography identified a multilobulated vegetation on the conduit valve. in case #2, transthoracic, transesophageal and intracardiac echocardiography were performed and were without evidence of cardiac vegetations, however pulmonic ...	2016	28027277
corticosteroid treatment for prolonged fever in hepatosplenic cat-scratch disease.	hepatosplenic cat-scratch disease (csd) may cause prolonged fever. we present the case of a 4-year-old boy with confirmed hepatosplenic csd with fever lasting 3 months despite use of multiple different antimicrobial agents. the patient became afebrile soon after corticosteroid therapy was started. our case indicates corticosteroids may be useful in patients with hepatosplenic csd and prolonged fever.	2016	28006985
seronegative disseminated bartonella spp. infection in an immunocompromised patient.	an 11 year old, hispanic girl with a history of b-cell acute lymphoblastic leukemia was admitted to the hospital for symptoms compatible with bartonella henselae infection. the first molecularly diagnosed case of disseminated bartonella henselae infection was reported in an immunocompromised patient in lima, peru. the analysis was confirmed by polymerase chain reaction and automated sequencing of a liver biopsy sample, even though the serologic tests were negative. in conclusion, bartonella spp. ...	2016	27955752