Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| strategy for 3-d computed tomography diagnosis and treatment of small pulmonary arteriovenous fistula. | in a patient with left hemianopsia, computed tomography (ct) and magnetic resonance imaging revealed an intracranial space-occupying lesion in the right occipital region. a cerebral abscess was removed at craniotomy. enhanced pulmonary ct showed a small coin lesion in the peripheral lingula. and at 3-d ct two nidi with feeding arteries and draining veins were seen, indicating pulmonary arteriovenous fistula. lingular segmentectomy was performed. | 2000 | 10816068 |
| induction of human immunodeficiency virus type 1 expression by anaerobes associated with bacterial vaginosis. | bacterial vaginosis (bv) is a common disorder characterized by increased levels of anaerobic bacteria in the genital tract. bv has been associated with an increased rate of sexual transmission of human immunodeficiency virus (hiv). the effects of bv-associated anaerobic bacteria on hiv expression in monocytoid cells and t cells were examined. peptostreptococcus asaccharolyticus and prevotella bivia stimulated hiv expression in monocytoid cells, whereas bacteroides ureolyticus, peptostreptococcus ... | 2000 | 10823756 |
| review of the in vitro activity of gemifloxacin against gram-positive and gram-negative anaerobic pathogens. | published reports on the in vitro activity of gemifloxacin mesylate (sb 265805), a new fluoronaphthyridone, against anaerobic pathogens are reviewed here. the studies used a variety of media, inocula and antimicrobial agents. using a proposed breakpoint of 0.5 mg/l, these studies showed that gemifloxacin had generally higher potency against gram-positive anaerobes (clostridium perfringens, all peptostreptococcus spp.) and fusobacteria (fusobacterium nucleatum, fusobacterium necrophorum) and mode ... | 2000 | 10824034 |
| in vitro activities of mk-826 (l-749,345) against 363 strains of anaerobic bacteria. | the activity of mk-826 was compared to the activities of cefoxitin, ceftriaxone, imipenem, and meropenem against 363 gram-negative and gram-positive anaerobes by using nccls procedures. at least 98% of the strains were susceptible to the carbapenems. all strains of clostridium perfringens, fusobacterium nucleatum, peptostreptococcus, and sutterella wadsworthensis were susceptible to all agents tested. | 2000 | 10898709 |
| toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection. | c3h/hej mice have an impaired ability to respond to lipopolysaccharide (lps) due to a mutation in the gene that encodes toll-like receptor 4 (tlr4). the effect of tlr4 deficiency on host responses to endodontic infections is unknown. in the present study, we compared periapical bone destruction, sepsis, and inflammatory cytokine production in lps-hyporesponsive c3h/hej and wild-type control c3h/heouj mice. the mandibular first molars of both strains were subjected to pulpal exposure and infectio ... | 2000 | 10899873 |
| interleukin-1 receptor signaling rather than that of tumor necrosis factor is critical in protecting the host from the severe consequences of a polymicrobe anaerobic infection. | infection of the dental pulp leads to an osteolytic lesion that results from a polymicrobial infection consisting largely of pathogenic anaerobes. infection causes significant morbidity and mortality mediated by bacterial factors and in some cases by the up-regulation of inflammatory cytokines. the inflammatory cytokines interleukin-1 (il-1) and tumor necrosis factor (tnf), in particular, play a complex and central role in the responses to microbial pathogens. however, relatively little is known ... | 2000 | 10899881 |
| characterization of bacterial orofacial infections using a new murine model. | we devised a new murine orofacial infection model using bacteria from odontogenic infection origins and characterized the experimental infections. in this model, bacteria were injected into the submandible of mice. streptococcus constellatus and peptostreptococcus micros produced a single abscess at the injection site and their abscess-forming and lethal abilities were low: the median abscess-forming dose (af(50)) of s. constellatus and p. micros were 10(8.5-10.7)and 10(10.2-10.6)cfu/mouse, and ... | 2000 | 10906266 |
| "checkerboard" assessments of periodontal microbiota and serum antibody responses: a case-control study. | we explored the association between subgingival microbial profiles and serum igg responses to periodontal microbiota in relation to clinical periodontal status. | 2000 | 10914791 |
| [bacterial vaginosis. epidemiology and risk factors]. | bacterial vaginosis (bv) is a change in vaginal ecosystem where lactobacilli dominate, flora is absent or greatly reduced, and replaced with a mixed, predominantly anaerobic flora, consisting of gardnerella vaginalis, mycoplasma hominis, mobiluncus spp, bacteroides spp, prevotela spp, peptostreptococcus spp, fusobacterium spp and porphyromonas spp. the concentration of bacteria increases from 100 to 1000 fold in women with bv compared to healthy women. bv has been formerly known as nonspecific v ... | 2000 | 10916461 |
| in vitro bacterial interference in the nasopharynx of otitis media-prone and non-otitis media-prone children. | to compare the frequency of recovery of potential pathogens and aerobic- and anaerobic-interfering bacteria in the nasopharynx of otitis media-prone (omp) with that in non-omp (n-omp) children. | 2000 | 10922236 |
| critical role of beta-hairpin formation in protein g folding. | comparison of the folding mechanisms of proteins with similar structures but very different sequences can provide fundamental insights into the determinants of protein folding mechanisms. despite very little sequence similarity, the approximately 60 residue igg binding domains of protein g and protein l both consist of a single helix packed against a four-stranded sheet formed by two symmetrically disposed beta-hairpins. we demonstrate that, as in the case of protein l, one of the two beta-turns ... | 2000 | 10932252 |
| evaluation of a phenotypic scheme for identification of the 'butyrate-producing' peptostreptococcus species. | gram-positive anaerobic cocci (gpac) are isolated from approximately one quarter of all infections involving anaerobic bacteria. however, studies of the significance of this group of pathogens have been hindered by an inadequate taxonomy and the lack of a valid identification scheme. in the present study, a phenotypic scheme for the identification of 'butyrate-producing' gpac based on the analysis of volatile fatty acid profiles by gas-liquid chromatography, biochemical profiles (including the u ... | 2000 | 10933261 |
| microbiology of healthy and diseased adenoids. | to determine the qualitative and quantitative microbiology of core adenoid tissue obtained from four groups of 15 children each, with recurrent otitis media (rom), recurrent adenotonsillitis (rat), obstructive adenoid hypertrophy (oah), and occlusion or speech abnormalities (controls). | 2000 | 10852520 |
| features of severe periodontal disease in a teenager with chédiak-higashi syndrome. | chédiak-higashi syndrome (c-hs) is a rare congenital disease characterized by defective neutrophil function with abnormal lysosomal inclusions, neutropenia, and reduced chemotaxis. the complete syndrome includes oculocutaneous albinism with photophobia, neurologic features, recurrent infections, and enterocolitis. | 2000 | 10872965 |
| ulcus vulvae acutum. | an acute vulvar ulcer was diagnosed based on a case history of a 17-year-old girl with genital ulcers. no relevant causative factors could be established. the gangrenous form of the disease, cutaneous anergy, and the cultured anaerobic pathogens suggested the possibility of an infectious pathogenesis. | 2000 | 10879308 |
| in vitro activity of telithromycin (hmr 3647) and seven other antimicrobial agents against anaerobic bacteria. | we assessed the in vitro activity of telithromycin (hmr 3647) and seven other antimicrobials against 292 strains of obligately anaerobic bacteria. mics were determined with the microdilution technique and wilkins-chalgren broth according to din 58940-83. mic50/mic90s (mg/l) for telithromycin were 4/4 for bacteroides fragilis, bacteroides ovatus and bacteroides thetaiotaomicron, 2/4 for fusobacterium spp. and bilophila wadsworthia, 2/2 for bacteroides caccae, 1/4 for bacteroides vulgatus, 0.25/4 ... | 2000 | 10882699 |
| the periodontal abscess (i). clinical and microbiological findings. | little information is available regarding the diagnosis and microbiology of periodontal abscesses. the aim of this descriptive clinical and microbiological study was to provide more information in order to help in the characterisation of the periodontal abscess associated to periodontitis. | 2000 | 10883867 |
| [cerebral abscess in an immunocompetent patient]. | 2000 | 10893748 | |
| evaluation of the oxyrase oxyplate anaerobe incubation system. | the oxyrase oxyplate anaerobe incubation system was evaluated for its ability to support the growth of clinically significant anaerobic bacteria previously identified by the anaerobe reference laboratory at the centers for disease control and prevention. the results were compared with those obtained with conventional anaerobe blood agar plates incubated in an anaerobe chamber. we tested 251 anaerobic bacterial strains. plates were read at 24, 48, and 72 h; growth was scored by a numerical coding ... | 2000 | 10655335 |
| in vitro and in vivo antibacterial activities of biapenem in the fields of obstetrics and gynecology. | biapenem is a new injectable carbapenem antibiotic which has favorable pharmacokinetic properties, and is stable to hydrolysis by dehydropeptidase i. biapenem inhibited more than 90% of clinical isolates of streptococcus agalactiae, escherichia coli, peptostreptococcus magnus, bacteroides fragilis and prevotella bivia at the concentration of 3.13 mg/l. the mic(90) of biapenem against pseudomonas aeruginosa was lower than that of panipenem, equivalent to that of imipenem, and greater than that of ... | 2000 | 10671758 |
| past administration of beta-lactam antibiotics and increase in the emergence of beta-lactamase-producing bacteria in patients with orofacial odontogenic infections. | the purpose of this study was to determine the current status of beta-lactamase-producing bacteria in orofacial odontogenic infections. | 2000 | 10673654 |
| [the dynamics of the colonization by the microbial flora of the mouth of the different materials used for dental prosthetics]. | colonization of materials used for making dentures with oral microflora was studied in 12 patients with chronic generalized medium severe periodontitis during remission. time course of dentures colonization with representatives of oral microflora (s. sanguis, peptostreptococcus sp., prevotella oralis) and with bacteria pathogenic for the periodontium (prevotella melaninogenica, a. naeslundii, fusobacterium sp.) depends on the material from which the dentures are made. minimal colonization of bac ... | 2000 | 10693351 |
| lack of antimicrobial effect on periodontopathic bacteria by ultrasonic and sonic scalers in vitro. | the purpose of this study was to assess the antimicrobial effects of a sonic and ultrasonic scaler generally used for subgingival scaling on gram-negative and gram-positive periodontopathic bacteria. | 2000 | 10703657 |
| peptostreptococcus micros smooth and rough genotypes in periodontitis and gingivitis. | two genotypes can be distinguished within the species peptostreptococcus micros: a smooth (sm) and a rough (rg) type. to date no systematic study has been performed on the prevalence and proportion of both types in untreated periodontitis patients and subjects without destructive periodontal disease. therefore, the present study was performed to investigate: 1) the relative importance of the sm and the rg genotype of p micros in periodontitis and gingivitis; 2) the correlation between smoking an ... | 2000 | 10711611 |
| a case of paraspinal abscess and diskitis due to peptostreptococcus micros. | 2000 | 10722468 | |
| crystallization and preliminary x-ray diffraction studies of mutants of b1 igg-binding domain of protein l from peptostreptococcus magnus. | the small 62-residue igg-binding domain b1 of protein l from peptostreptococcus magnus (ppl-b1) has proven to be a simple system for the study of the thermodynamics and kinetics of protein folding. x-ray diffraction studies have been initiated in order to determine how the thermostability, folding and unfolding rates of a series of point mutations spanning ppl-b1 correlate with the high-resolution structures. to this end, a tryptophan-containing variant of ppl-b1 (herein known as wild type) and ... | 2000 | 10739935 |
| expression of a heterologous glutamate dehydrogenase gene in lactococcus lactis highly improves the conversion of amino acids to aroma compounds. | the first step of amino acid degradation in lactococci is a transamination, which requires an alpha-keto acid as the amino group acceptor. we have previously shown that the level of available alpha-keto acid in semihard cheese is the first limiting factor for conversion of amino acids to aroma compounds, since aroma formation is greatly enhanced by adding alpha-ketoglutarate to cheese curd. in this study we introduced a heterologous catabolic glutamate dehydrogenase (gdh) gene into lactococcus l ... | 2000 | 10742211 |
| aerobic and anaerobic bacteriology of concurrent chronic otitis media with effusion and chronic sinusitis in children. | to correlate the aerobic and anaerobic microbiologic findings of concurrent chronic otitis media with effusion and chronic maxillary sinusitis. | 2000 | 10680868 |
| postantibiotic effects and bactericidal activities of clarithromycin-14-hydroxy-clarithromycin, versus those of amoxicillin-clavulanate, against anaerobes. | the bactericidal activities and postantibiotic effects (pae) of clarithromycin-14-hydroxy-clarithromycin and amoxicillin-clavulanate against bacteroides fragilis and peptostreptococcus anaerobius were determined. a concentration of twice the mic resulted in bactericidal activity against four of four and three of four organisms at 24 h with clarithromycin-14-hydroxy-clarithromycin and amoxicillin-clavulanate, respectively. the pae of clarithromycin-14-hydroxy-clarithromycin was 1.44 to 3.20 h, co ... | 2000 | 10681358 |
| peptostreptococcus micros coaggregates with fusobacterium nucleatum and non-encapsulated porphyromonas gingivalis. | coaggregation is one of the potential colonization strategies of oral microorganisms, often involving fimbrial structures in the interactions. in this study, the coaggregation characteristics of the rough and smooth genotypes of the periodontal pathogen peptostreptococcus micros were compared to investigate the role of the fibril-like structures of the rough genotype in coaggregation. of the 11 oral species tested, only fusobacterium nucleatum strains and non-encapsulated porphyromonas gingivali ... | 2000 | 10612731 |
| intraabdominal abscess managed successfully via the laparoscopic approach. | a rare complication of laparoscopic fundoplication-an intraabdominal abscess located between the fundus and the caudate lobe of the liver-is described. a 41-year-old man had undergone a laparoscopic nissen-rossetti fundoplication for longstanding gastroesophageal reflux disease. on the 5th postoperative day, the patient's general condition became worse, and he developed intermittent-remittent fever (40 degrees c), an elevated white blood cell count (wbc), and an accelerated sedimentation rate. e ... | 2000 | 11265065 |
| calibration of the disk diffusion test for trovafloxacin susceptibility testing of four anaerobic species. | to study trovafloxacin susceptibility among clinical isolates of four anaerobic bacterial species using minimum inhibitory concentrations (mic) determinations, e test assays and disk diffusion test results and to calibrate the disk diffusion method for these species using single strain regression analysis (sra). | 2000 | 11168107 |
| early colonization of dental implants by putative periodontal pathogens in partially edentulous patients. | there is limited scientific information available on the early colonization of the peri-implant pockets in partially edentulous individuals. knowledge about this process is one step in better understanding the etiology and pathogenesis of peri-implantitis. in this study, the early colonization of the peri-implant pockets by putative periodontal pathogens was studied in 20 partially edentulous individuals using anaerobic culture techniques. at baseline, the presence and levels of putative periodo ... | 2000 | 11168244 |
| growth inhibitory activity of gutta-percha points containing root canal medications on common endodontic bacterial pathogens as determined by an optimized quantitative in vitro assay. | gutta-percha points containing calcium hydroxide, zinc oxide (zno), a mixture of zno and chlorhexidine (zno/chx), iodine-polyvinylpyrrolidone (zno/j-pvp), or a mixture of chx and j-pvp and zno (zno/chx/j-pvp) were tested for their ability to inhibit growth of pure cultures of bacterial species commonly involved in endodontic infections (peptostreptococcus micros, streptococcus intermedius, enterococcus faecalis, and porphyromonas gingivalis). to quantitate growth inhibition, an in vitro assay wa ... | 2000 | 11199764 |
| molecular epidemiology and association of putative pathogens in root canal infection. | the purpose of this study was to investigate the epidemiology of putative pathogens in root canals with apical periodontitis and to determine the associations among the putative pathogens. eighteen symptomatic and 20 asymptomatic teeth from 36 subjects were studied. this research was performed with polymerase chain reaction and hybridization using rrna-based oligonucleotide probes. the most frequently found species was fusobacterium sp. (68.4%), followed by peptostreptococcus micros (44.7%) and ... | 2000 | 11199802 |
| [the influence of anaerobic bacteria and mycoplasma isolated from the genital tract on mast cell activation]. | nowadays, it is known that mast cells, numerously appearing in all organs and being a source of a wide range of mediators and cytokines, are involved both in physiological and pathological processes. the aim of our study was to examine whether vaginal bacteria, especially those participating in bacterial vaginosis, are able to activate mast cells to mediators secretion. the study was done on rat peritoneal mast cells. the mast cells were incubated in vitro with suspensions of bacteroides capillo ... | 2000 | 11286181 |
| the effect of statherin and its shortened analogues on anaerobic bacteria isolated from the oral cavity. | the susceptibility (mic) of 44 strains of anaerobic bacteria isolated from the oral cavity and 3 standard strains to statherin and its c-terminal fragments with sequences qyqqytf, yqqytf, qqytf, qytf and ytf was determined by means of plate dilution technique in brucella agar with 5% content of defibrinated sheep's blood, menadione and hemin. the culture was anaerobic. as shown, at concentrations from 12.5 to 100 microg/ml statherin and its c-terminal fragments inhibited the growth of anaerobic ... | 2000 | 11293657 |
| comparison of microbial composition in the subgingival plaque of adult crowded versus non-crowded dental regions. | it has been reported in the literature that certain species of bacteria (periodontopathogens) present in the subgingival plaque are associated with destructive periodontal disease. the purpose of this study was to investigate and compare the presence and proportional distribution of periodontopathogens in the subgingival plaque of adult crowded versus non-crowded dental regions. thirty adult patients with anterior dental crowding were selected from the orthodontic clinic of the university of pen ... | 2000 | 11307190 |
| the consequences of suppression of anaerobic bacteria. | anaerobic bacteria such as bacteroides fragilis, peptostreptococcus species, and fusobacterium species, when accompanied by aerobic bacteria or in the presence of dead tissue, can cause severe infections. this article discusses the most common type of anaerobic infection, i.e., infection after colonic contamination of the abdominal cavity and soft tissues. colonic anaerobes rarely cause infections as solitary pathogens. mixed infections of aerobes and anaerobes are treated by source control, sur ... | 2000 | 12594909 |
| linezolid: a new antibiotic. | the u.s. food and drug administration recently approved linezolid for the treatment of patients with methicillin-resistant staphylococcal and vancomycin-resistant enterococcal infections. this oxazolidinone antibacterial agent represents the first approved antibiotic of a new structural class in 35 years. linezolid is a synthetic compound that acts by inhibiting the initiation complex formation in bacterial protein synthesis, a mechanism of action distinct from other commercially available antib ... | 2000 | 12847568 |
| ocular infections due to anaerobic bacteria. | the increased recovery of anaerobic bacteria in clinical infection has led to greater appreciation of these organisms in ocular infections. in studies that employed adequate method for recovery of anaerobes they were isolated from about a third of patients with conjunctivitis, half of the time in pure culture. the predominant recovered anaerobes were clostridium spp., gram-negative anaerobic bacilli, and peptostreptococcus spp. anaerobic bacteria were also recovered from patients who wore contac ... | 2001 | 14531629 |
| phospholipid analogue profiles of peptostreptococcus, micromonas, and finegoldia species analysed by fast atom bombardment mass spectrometry. | species of peptostreptococcus cause a variety of infections, primarily abscesses of soft tissues, joints, and mucous membranes. the aim of this study was to compare the phospholipid analogue profiles of peptostreptococcus species, represented by p. anaerobius, p. asaccharolyticus, p. indolicus, p. lacrimalis, and p. prevotii; micromonas micros (p. micros) and finegoldia magna (p. magnus). after anaerobic growth on blood-faa, lipids extracted by chloroform-methanol (2:1 v/v) were purified, then a ... | 2001 | 15049457 |
| [the microflora of ulzerous zone mucosa in patients with duodenal ulcer]. | bacteriological study of the biopsies taken from gastric and duodenal mucosa of 10 healthy volunteers and 74 patients with duodenal ulcer, was carried out. in the gastroduodenal zone of healthy subjects microorganisms of 6 genera (streptococcus, candida, staphylococcus, bacillus, helicobacter and lactobacillus) were detected. h. pylori was isolated in 20% of cases only in biopsy specimens taken from the antral section of the stomach of healthy as monoculture or in combination with c. albicans. i ... | 2001 | 11871291 |
| maternal periodontitis and prematurity. part ii: maternal infection and fetal exposure. | clinical data from the first 812 deliveries from a cohort study of pregnant mothers entitled oral conditions and pregnancy (ocap) demonstrate that both antepartum maternal periodontal disease and incidence/progression of periodontal disease are associated with preterm birth and growth restriction after adjusting for traditional obstetric risk factors. in the current study we present measures of maternal periodontal infection using whole chromosomal dna probes to identify 15 periodontal organisms ... | 2001 | 11887461 |
| immunoglobulin-binding domains of peptostreptococcal protein l enhance vaginal colonization of mice by streptococcus gordonii. | protein l, an immunoglobulin-binding protein of some strains of the anaerobic bacterium peptostreptococcus magnus, has been hypothesized to be a virulence determinant in bacterial vaginosis. in order to investigate the role of protein l in peptostreptococcal virulence, the ig-binding domains of protein l were expressed at the surface of the human oral commensal streptococcus gordonii. recombinant streptococci were used in vaginal colonization experiments, and protein l-expressing s. gordonii dem ... | 2001 | 11312616 |
| amoxicillin plus metronidazole in the treatment of adult periodontitis patients. a double-blind placebo-controlled study. | the aim of this double-blind, parallel study was to evaluate the adjunctive effects of systemically administered amoxicillin and metronidazole in a group of adult periodontitis patients who also received supra- and subgingival debridement. | 2001 | 11314884 |
| [cellulitis and necrotizing fasciitis: microbiology and pathogenesis]. | streptococcus pyogenes is a common cause of necrotizing cutaneous infections in otherwise healthy children and adults. several surface components are involved in the processes of adherence and invasiveness, such as protein m and capsulae. streptolysin o and other bacterial products, such as pyrogenic exotoxins, are involved in tissue injury and necrosis. toxins a and c act as superantigens and are expressed by strains associated with the toxic shock syndrome. staphylococcus aureus, alone or in a ... | 2001 | 11319369 |
| linezolid: a review of its use in the management of serious gram-positive infections. | linezolid is the first of a new class of antibacterial drugs, the oxazolidinones. it has inhibitory activity against a broad range of gram-positive bacteria, including methicillin-resistant staphylococcus aureus (mrsa), glycopeptide-intermediate s. aureus (gisa), vancomycin-resistant enterococci (vre) and penicillin-resistant streptococcus pneumoniae. the drug also shows activity against certain anaerobes, including clostridium perfringens, c. difficile, peptostreptococcus spp. and bacteroidesfr ... | 2001 | 11324682 |
| a microbiological study of papillon-lefévre syndrome in two patients. | to analyse the microflora of subgingival plaque from patients with papillon-lefévre syndrome (pls), which is a very rare disease characterised by palmar-plantar hyperkeratosis with precocious periodontal destruction. | 2001 | 11328836 |
| bacteria isolated after unsuccessful endodontic treatment in a north american population. | the purpose of this study was to determine the composition of the microbial flora present in teeth after the failure of root canal therapy in a north american population. these results were then compared with those of the previous scandinavian studies. | 2001 | 11346739 |
| relationship of cigarette smoking to the subgingival microbiota. | the relationship of cigarette smoking to the composition of the subgingival microbiota is not clear. some studies indicated higher levels of certain species in smokers, while other studies failed to detect differences in the microbiota between subjects with different smoking histories. thus, the purpose of the present investigation was to examine the prevalence, proportions and levels of the subgingival species in adult subjects who were current, past or never smokers. | 2001 | 11350499 |
| comparative in vitro activities of gemifloxacin, other quinolones, and nonquinolone antimicrobials against obligately anaerobic bacteria. | the in vitro activity of gemifloxacin was compared to that of other quinolone and nonquinolone antimicrobials against 204 anaerobes by the agar dilution technique. the data indicate that gemifloxacin has a rather selective anaerobic activity. most peptostreptococcus, porphyromonas, and fusobacterium species are susceptible, while gemifloxacin's activity against other gram-negative anaerobes appears to be variable. | 2001 | 11353648 |
| vaginal microflora associated with bacterial vaginosis in nonpregnant women: reliability of sialidase detection. | to determine the prevalence of gardnerella vaginalis, anaerobic bacteria and mycoplasma hominis in vaginal specimens of women with and without bacterial vaginosis (bv) as well as to determine the sensitivity and specificity of the direct sialidase assay of vaginal fluid as a rapid test for diagnosing this syndrome. | 2001 | 11368254 |
| recovery of anaerobic bacteria from 3 patients with infection at a pierced body site. | we describe 3 adolescents who developed infections due to anaerobes at pierced body sites: the nipple, the umbilicus, and the nasal septum. anaerobes (prevotella intermedia and peptostreptococcus anaerobius) were recovered from pure culture of specimens obtained from 1 patient with nipple infection and were mixed with aerobic bacteria in cultures of specimens obtained from 2 patients (streptococcus aureus, peptostreptococcus micros, and prevotella melaninogenica were recovered from a patient wit ... | 2001 | 11389513 |
| smoking affects the subgingival microflora in periodontitis. | tobacco smoking has been identified as one major risk factor for destructive periodontal disease. scaling and root planing have been shown to be less effective in smokers with periodontitis. the aim of the present study was to compare the subgingival microbial flora of treated and untreated smokers and non-smokers. | 2001 | 11394403 |
| in vitro activity and post-antibiotic effect of quinupristin/dalfopristin (synercid). | the in vitro activities of quinupristin/dalfopristin (synercid), ampicillin, erythromycin, clarithromycin, vancomycin, teicoplanin, ciprofloxacin and tetracycline were examined and compared against 526 gram-positive bacteria. the minimal inhibitory concentrations (mics) for quinupristin/dalfopristin against staphylococcus aureus, including methicillin-resistant strains, were low (mic(90) = 0.5 mg/l), and were comparable with those of vancomycin and teicoplanin. this compound was superior to the ... | 2001 | 11399860 |
| [pharmacological and pharmacokinetic properties of azithromycin (zithromac), a novel 15-membered ring macrolide antibacterial agent]. | azithromycin (zithromac), a 15-membered ring macrolide antibacterial agent, was approved to be manufactured in japan in march 2000. it showed good in vitro and/or in vivo antibacterial activities against staphylococcus aureus, streptococcus pneumoniae, streptococcus pyogenes, peptostreptococcus micros, haemophilus influenzae, moraxella catarrhalis, mycoplasma pneumoniae and chlamydia pneumoniae. its activity against h. influenzae was particularly more potent than that of currently used macrolide ... | 2001 | 11411344 |
| role of aromatic stacking interactions in the modulation of the two-electron reduction potentials of flavin and substrate/product in megasphaera elsdenii short-chain acyl-coenzyme a dehydrogenase. | the effects of aromatic stacking interactions on the stabilization of reduced flavin adenine dinucleotide (fad) and substrate/product have been investigated in short-chain acyl-coenzyme a dehydrogenase (scad) from megasphaera elsdenii. mutations were made at the aromatic residues phe160 and tyr366, which flank either face of the noncovalently bound flavin cofactor. the electrochemical properties of the mutants were then measured in the presence and absence of a butyryl-coa/crotonyl-coa mixture. ... | 2001 | 11412126 |
| microbiological characteristics of subgingival microbiota in adult periodontitis, localized juvenile periodontitis and rapidly progressive periodontitis subjects. | to describe the prevalence of the cultivable subgingival microbiota in periodontal diseases and to draw attention to the polymicrobial nature of periodontic infections. | 2001 | 11422244 |
| untreated periodontal disease in indonesian adolescents. subgingival microbiota in relation to experienced progression of periodontitis. | in an indonesian population deprived of regular dental care, the experienced progression of disease between baseline (1987) and follow-up (1994) was investigated in relation to the composition of the subgingival microbiota at follow-up. at baseline the age ranged from 15 to 25 years. clinical and microbiological evaluation was completed in 158 of the 167 subjects available at follow-up. | 2001 | 11422582 |
| mutans streptococci in subgingival plaque of treated and untreated patients with periodontitis. | the etiology of root caries is thought to be identical to coronal caries, though root caries seem to be more complicated because of the higher susceptibility of exposed roots (dentin) by periodontal therapy to demineralization than intact enamel. this implies that mutans streptococci are the most likely pathogens in the development of root caries. although it is known that both the numbers of mutans streptococci and the frequency of isolation in root caries lesions are negatively correlated with ... | 2001 | 11422591 |
| computer-based redesign of a protein folding pathway. | a fundamental test of our current understanding of protein folding is to rationally redesign protein folding pathways. we use a computer-based design strategy to switch the folding pathway of protein g, which normally involves formation of the second, but not the first, beta-turn at the rate limiting step in folding. backbone conformations and amino acid sequences that maximize the interaction density in the first beta-hairpin were identified, and two variants containing 11 amino acid replacemen ... | 2001 | 11427890 |
| cavernous sinus thrombophlebitis caused by sphenoid sinusitis--report of autopsy case. | a 34-year-old man developed fever, headache, nausea, double vision, exophthalmus, ptosis, disturbance of vision and oculomotor nerve palsy. magnetic resonance imaging and cerebral angiography led to the clinical diagnoses of cavernous sinus thrombophlebitis and suspicion of bacterial aneurysm of the left internal carotid artery, respectively. peptostreptococcus was detected in blood culture analysis. he died 15 days after admission. systemic organs showed several septic changes. in particular, t ... | 2001 | 11430492 |
| nugent score related to vaginal culture in pregnant women. | to relate gram-stained smears, using the nugent criteria, to quantitative and qualitative vaginal cultures in pregnant women. | 2001 | 11430961 |
| recovery of anaerobic bacteria from four children with postthoracotomy sternal wound infection. | the cases of 4 children who developed postthoracotomy sternal wound infection caused by anaerobic bacteria are presented. the predominate anaerobes were peptostreptococcus species and pigmented prevotella species. polymicrobial infection was present in all cases, and aerobic bacteria also were recovered in 2 instances. all patients responded to surgical debridement and antimicrobials effective against the isolated aerobic and anaerobic bacteria. these findings highlight the potential importance ... | 2001 | 11433096 |
| chi1 torsion angle dynamics in proteins from dipolar couplings. | experiments are presented for the measurement of one-bond carbon-proton dipolar coupling values at ch and ch2 ositions in 13c-labeled, approximately 50% fractionally deuterated proteins. 13cbeta-1hbeta dipolar couplings have been measured for 38 of 49 possible residues in the 63-amino-acid b1 domain of peptostreptococcal protein l in two aligning media and interpreted in the context of side-chain chi1 torsion angle dynamics. the beta protons for 18 of the 25 beta-methylene-containing amino acids ... | 2001 | 11448195 |
| antibacterial activity and post-antibiotic effect of flurithromycin compared with other macrolides and penicillins against periodontal pathogens. | in this study the authors examined the activity of flurithromycin compared to that of erythromycin, spiramycin and penicillin against 107 strains of various species supposed to cause periodontitis. the range of mics of flurithromycin was: < or =0.06-2 mg/l for p. gingivalis (28 isolates), 0.06-2 mg/l for p. melaninogenica (7), 0.5-4 mg/l for p. intermedia (5), 0.25-8 mg/l for prevotella sp. (8), 1-16 mg/l for f. nucleatum (14), 0.12-0.5 mg/l for w. recta (2), 0.5-32 mg/l for e. corrodens, 0.5-2 ... | 2001 | 11450882 |
| bacteriology and beta-lactamase activity in acute exacerbation of chronic bronchitis. | to assess the bacteriology of beta-lactamase (bl) enzyme activity in sputum of 40 patients with acute exacerbation of chronic bronchitis (aecb). | 2001 | 11468101 |
| [bacteriologic investigation of periodontal infections]. | the gingivitis and periodontitis are very common diseases in hungary: more than 80% of the adult population suffers with gingivitis and 15-20% has destructive periodontitis. the composition of peridontopathogenic bacterial flora is totally different from that of the bacterial flora causing dental infections. in periodontal infections dominantly facultative and obligatory anaerobic microorganisms occur (actinobacillus actinomycetemcomitans (a. actinomycetemcomitans), porphyromonas gingivalis (p. ... | 2001 | 11480243 |
| effect of amoxycillin with or without clavulanate on adenoid bacterial flora. | the effect of antimicrobial therapy with amoxycillin (amx) or co-amoxiclav (amc) on the adenoid bacterial flora of 45 children with recurrent otitis media (rom), scheduled for elective adenoidectomy, was studied. patients were randomized before surgery into three groups of 15, having had either no antibiotic therapy (control), or 10 days of therapy with amx or amc. core adenoid tissues were quantitatively cultured for aerobic and anaerobic bacteria. polymicrobial aerobic-anaerobic flora was pres ... | 2001 | 11481299 |
| an in vitro evaluation of the antimicrobial efficacy of irrigants on biofilms of root canal isolates. | the bactericidal effect of four antimicrobial agents was investigated against single-species biofilms derived from a range of root canal isolates. | 2001 | 11482142 |
| antibacterial properties of electron beam-sterilized gutta-percha cones. | the purpose of the study was to determine the effect of electron beam sterilization on gutta-percha cones (gpcs) at different times after sterilization. an agar diffusion test was used with -one aerobic bacterium (bacillus subtilis) and five oral anaerobic bacteria (fusobacterium nucleatum, peptostreptococcus micros, porphyromonas gingivalis, propionibacterium acnes, and veillonella parvula). with each microorganism 30 agar plates were prepared, evenly distributed among three groups (group 1: un ... | 2001 | 11487145 |
| the clinical relevance of microbiologic testing: a comparative analysis of microbiologic samples secured from the same sites and cultured in two independent laboratories. | a field study using five different private periodontal practices was conducted; it compared two microbiologic culture samples simultaneously secured from the same sites within 23 individual patients and submitted for bacterial identification and antibiotic sensitivity testing to two separate laboratories. the results from the two laboratories were often different. in no instance did both laboratories agree on the presence of identical bacterial species. when only bacteria above threshold levels ... | 2001 | 11490400 |
| proposal of the genera anaerococcus gen. nov., peptoniphilus gen. nov. and gallicola gen. nov. for members of the genus peptostreptococcus. | members of genus peptostreptococcus have previously been found to be distantly related to the type species, peptostreptococcus anaerobius, on the basis of 16s rdna sequence similarities. they were divided into three major phylogenetic groups, and their peptidoglycan structure and biochemical traits differed between groups. the reclassification of the species of these three groups into three new genera, peptoniphilus gen. nov., anaerococcus gen. nov. and gallicola gen. nov., is proposed. the genu ... | 2001 | 11491354 |
| viable bacteria in root dentinal tubules of teeth with apical periodontitis. | two sets of teeth with apical periodontitis were collected at different geographic locations to study the identity of bacteria left in the root dentinal tubules. root dentin of 20 of these teeth was cultured from three locations between pulp and cementum (a, b, and c). in addition dentin from eight teeth was examined histologically. using the culturing technique bacteria were found in 77% of the dentin samples from set 1 (amsterdam) and in 87.5% of the dentin samples from set 2 (glasgow). at gre ... | 2001 | 11491642 |
| molecular analysis of peptostreptococcus micros isolates from patients with periodontitis. | recent studies provide strong evidence implicating peptostreptococcus micros in the pathogenesis of various oral infections, including oropharyngeal abscesses and periodontal disease. to date, very little is known regarding the role of p. micros in periodontal disease. therefore, a genetic analysis was initiated to differentiate among strains of p. micros infecting periodontal patients. | 2001 | 11495135 |
| molecular identification of microorganisms from endodontic infections. | a relatively wide range of bacteria have been isolated from root canals using standard culture techniques. however, only 50% of the bacteria in the oral cavity are cultivable (s. s. socransky et al., arch. oral biol. 8:278-280, 1963); hence, bacterial diversity in endodontic infections is underestimated. this study used a pcr-based 16s rrna gene assay, followed by cloning and sequencing of 16s rrna amplicons from a small subset of samples to assess the diversity of bacteria present in infected r ... | 2001 | 11526164 |
| [soft tissue infections caused by non-group a streptococci]. | 2001 | 11555914 | |
| bacteriology of adenoids and tonsils in children with recurrent adenotonsillitis. | adenoids and tonsils electively removed from 25 children with a history of recurrent group a beta-hemolytic streptococci (gabhs) adenotonsillitis were cultured for aerobic and anaerobic bacteria. two hundred twenty-four organisms (112 aerobes and facultatives, 110 anaerobes, and 2 candida albicans) were isolated from the tonsils, and 229 (111 aerobes and facultatives and 118 anaerobes) were isolated from the adenoids. mixed infection was present in all instances, with an average of 9.1 isolates ... | 2001 | 11558761 |
| [comparative study of chromatography-mass spectrography of microorganism's chemical markers in blood and intestinal mucosa bioptats]. | fatty acids, that are microorganism's markers in blood and jejunum's, ileum's, and large intestine's bioptats of the patients with irritable bowel syndrome were investigated with gas chromatography. markers of cl. perfringens, cl. difficile, enterococcus, streptomyces, enterobacterial, klebsiella, e. coli, peptostreptococcus, candida albicans, genus of streptococcus, of staphylococcus, of fusobacterium sp and others microorganisms were revealed. settling of intestinal mucosa was the same in jeju ... | 2001 | 11565126 |
| complex between peptostreptococcus magnus protein l and a human antibody reveals structural convergence in the interaction modes of fab binding proteins. | peptostreptococcus magnus protein l (ppl) is a multidomain, bacterial surface protein whose presence correlates with virulence. it consists of up to five homologous immunoglobulin binding domains that interact with the variable (vl) regions of kappa light chains found on two thirds of mammalian antibodies. | 2001 | 11587642 |
| [clinical and microbiological study of adult periodontal disease]. | the aim of this study was to carry out a microbiological evaluation of sites with and without clinical evidence of moderate and severe periodontitis and their correlation with clinical parameters. a total of 52 disease sites and 10 healthy sites were selected according to clinical criteria. the following clinical indexes were measured for all the sites: plaque index, gingival index, blood on probing, depth on probing and insertion level. samples of subgingival plaque were collected for culture a ... | 2001 | 11594003 |
| roles of native topology and chain-length scaling in protein folding: a simulation study with a go-like model. | we perform folding simulations on 18 small proteins with using a simple go-like protein model and analyze the folding rate constants, characteristics of the transition state ensemble, and those of the denatured states in terms of native topology and chain length. near the folding transition temperature, the folding rate k(f) scales as k(f) approximately exp(-c rco n(0.6)) where rco and n are the relative contact order and number of residues, respectively. here the topology rco dependence of the ... | 2001 | 11601854 |
| comparative in vitro activity of ertapenem and 11 other antimicrobial agents against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections. | we studied the comparative in vitro activity of ertapenem, a new carbapenem, against 240 aerobic and 180 anaerobic recent clinical bite isolates using an agar dilution method and an inoculum of 10(4) cfu/spot for aerobes and 10(5) cfu/spot for anaerobes. ertapenem inhibited 410/420 (98%) of the isolates tested at < or = 4 mg/l with only 4/5 campylobacter gracilis and 1/3 campylobacter rectus strains requiring . or = 16 mg/l for inhibition. ertapenem was only moderately active (mic 8 mg/l) agains ... | 2001 | 11679553 |
| efficacy of manual and powered toothbrushes (ii). effect on microbiological parameters. | the purpose of the present investigation was to determine the effect of self-performed supragingival plaque removal using either manual (crest complete) or power (braun 3d plaque remover) toothbrushing on supra and subgingival plaque composition. | 2001 | 11686813 |
| absence of a specific subgingival microflora in adults with down's syndrome. | periodontal disease in down's syndrome (ds) is generally characterized by a high degree of bone loss. bone loss of 5 mm or more is observed in 70% of these subjects. among ds subjects, considerable differences in disease progression occur. so far, no studies have been conducted in which specific properties of the subgingival microflora have been related to the condition observed. | 2001 | 11686820 |
| antagonism against vibrio cholerae by diffusible substances produced by bacterial components of the human faecal microbiota. | cholera vibrios sometimes survive, probably in low-level silent populations, in the small intestine of chronic carriers or pass through the gastrointestinal tract of a few individuals without causing diarrhoea or colonisation. to understand these situations, the present study used plate cultures (ex-vivo test) to investigate the frequency of appearance of an inhibitory halo against vibrio cholerae produced by faecal specimens from 92 healthy volunteers (40 females, 52 males) aged 4-61 years. the ... | 2001 | 11211223 |
| correlation between microbiology and previous sinus surgery in patients with chronic maxillary sinusitis. | aspirates of 108 chronically inflamed maxillary sinuses were processed for aerobic and anaerobic bacteria. there were 295 bacterial isolates: 109 aerobic and facultative, and 186 anaerobic. the predominant aerobic isolates were staphylococcus aureus (17 isolates), alpha-hemolytic streptococci (14), pseudomonas aeruginosa (12), moraxella catarrhalis (10), and haemophilus spp (8). the predominant anaerobes were peptostreptococcus spp (61), prevotella spp (45), fusobacterium spp (15), and propionib ... | 2001 | 11219522 |
| detection of peptostreptococcus micros dna in clinical samples by pcr. | peptostreptococcus micros is a gram-positive anaerobic coccus which, although considered to be a natural commensal of the human oral cavity, is associated with periodontal, endodontal and peritonsillar infections. identification of the organism has to date relied upon conventional culture methods and biochemical analyses. the purpose of this study was to develop a pcr method for rapid and specific identification of this organism in clinical samples. a pair of primers was selected, each of which ... | 2001 | 11232771 |
| microorganisms isolated from root canals presenting necrotic pulp and their drug susceptibility in vitro. | the knowledge about causative agents involved in endodontic infections is increasing, especially due to the improvement of culture techniques for anaerobic bacteria, showing that these microorganisms are predominant in this pathology. in this study, 31 canals with pulp necrosis were microbiologically analyzed before and after manipulation. obligate and facultative anaerobes, microaerophilic bacteria and yeasts were recovered from 24, 14, 5 and 2 clinical specimens, respectively. the most frequen ... | 2001 | 11240863 |
| microbial analysis of bone collected during implant surgery: a clinical and laboratory study. | dental implant surgery produces bone debris which can be used to correct bone defects in the "simultaneous-augmentation" technique. however, this debris is potentially contaminated with oral bacteria. therefore, this study examined bone debris collected during dental implant surgery in order 1) to identify the microbial contaminants and 2) to compare the effects of two different aspiration protocols on the levels of microbial contamination. twenty-four partially dentate patients were randomly al ... | 2001 | 11251657 |
| multicenter survey of the changing in vitro antimicrobial susceptibilities of clinical isolates of bacteroides fragilis group, prevotella, fusobacterium, porphyromonas, and peptostreptococcus species. | in vitro surveys of antimicrobial resistance among clinically important anaerobes are an important source of information that can be used for clinical decisions in the choice of empiric antimicrobial therapy. this study surveyed the susceptibilities of 556 clinical anaerobic isolates from four large medical centers using a broth microdilution method. piperacillin-tazobactam was the only antimicrobial agent to which all the isolates were susceptible. similarly, imipenem, meropenem, and metronidaz ... | 2001 | 11257040 |
| statistical theory for protein combinatorial libraries. packing interactions, backbone flexibility, and the sequence variability of a main-chain structure. | combinatorial experiments provide new ways to probe the determinants of protein folding and to identify novel folding amino acid sequences. these types of experiments, however, are complicated both by enormous conformational complexity and by large numbers of possible sequences. therefore, a quantitative computational theory would be helpful in designing and interpreting these types of experiment. here, we present and apply a statistically based, computational approach for identifying the proper ... | 2001 | 11178917 |
| structures of the b1 domain of protein l from peptostreptococcus magnus with a tyrosine to tryptophan substitution. | the three-dimensional structure of a tryptophan-containing variant of the igg-binding b1 domain of protein l has been solved in two crystal forms to 1.7 and 1.8 a resolution. in one of the crystal forms, the entire n-terminal histidine-tag region was immobilized through the coordination of zinc ions and its structural conformation along with the zinc coordination scheme were determined. however, the ordering of the histidine tag by zinc does not affect the overall structure of the rest of the pr ... | 2001 | 11264576 |
| single-site mutations induce 3d domain swapping in the b1 domain of protein l from peptostreptococcus magnus. | thermodynamic and kinetic studies of the protein l b1 domain (ppl) suggest a folding pathway in which, during the folding transition, the first beta hairpin is formed while the second beta hairpin and the alpha helix are largely unstructured. the same mutations in the two beta turns have opposite effects on the folding and unfolding rates. three of the four residues composing the second beta turn in ppl have consecutive positive phi angles, indicating strain in the second beta turn. | 2001 | 11709166 |
| [antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains]. | we determined the antibacterial activities of 4 carbapenems (imipenem, panipenem, meropenem and biapenem) and 2 forth generation cephems (cefozopran and cefepime) against 850 bacterial strains (18 species) isolated during the period from january 1998 through september 2000. the 4 carbapenems showed excellent antibacterial activities against methicillin-susceptible s. aureus (mssa), s. pneumoniae, e. faecalis, p. aeruginosa, m. (b). catarrhalis, b. fragilis and peptostreptococcus spp. as compared ... | 2001 | 11729712 |
| association of early onset periodontitis microbiota with aspartate aminotransferase activity in gingival crevicular fluid. | the objective of this study was to determine the relationship between the activity of the enzyme aspartate aminotransferase (ast) in gingival crevicular fluid (gcf) using the colorimetric periogard (ptm) test and the subgingival microflora in early onset periodontitis lesions. | 2001 | 11737506 |
| supragingival and subgingival microbiota of adult patients with down's syndrome. changes after periodontal treatment. | in this longitudinal study, five adult down's syndrome patients with periodontitis were placed on a frequent recall visit schedule (every 6 weeks) after treatment, in order to investigate: 1) the microbiological status, both supragingivally and subgingivally, and the changes that occurred after treatment and 2) the effect of frequent professional supragingival plaque control on the subgingival microbiota and clinical variables in these patients. the clinical variables recorded were probing pocke ... | 2001 | 11737662 |
| splenic abscess caused by peptostreptococcus species, diagnosed with the aid of abdominal computerized tomography and treated with percutaneous drainage and antibiotics: a case report. | we describe herein a 63-year-old patient with a splenic abscess due to peptostreptococcus spp., diagnosed with the aid of abdominal computerised tomography and treated with ultra-sound guided percutaneous drainage and antibiotics. the bacteriological characteristics of splenic abscesses are discussed. | 2001 | 11744179 |
| smoking and subgingival microflora in periodontal disease. | the present investigation was undertaken to analyze the influence of smoking on the periodontal disease associated subgingival microflora. the population included 33 smokers and 31 non-smokers in the age range 36-86 years. | 2001 | 11284533 |