Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| expression of helicobacter pylori urease genes in escherichia coli grown under nitrogen-limiting conditions. | helicobacter pylori produces a potent urease that is believed to play a role in the pathogenesis of gastroduodenal diseases. four genes (urea, ureb, urec, and ured) were previously shown to be able to achieve a urease-positive phenotype when introduced into campylobacter jejuni, whereas escherichia coli cells harboring these genes did not express urease activity (a. labigne, v. cussac, and p. courcoux, j. bacteriol. 173:1920-1931, 1991). results that demonstrate that h. pylori urease genes could ... | 1992 | 1313413 |
| profiles of toxin production by thermophilic campylobacter of animal origin. | seventy-five strains of campylobacter jejuni and c. coli, which were isolated from a variety of animal species, primarily poultry, were examined for production of toxin. polymyxin extracts were tested in in vitro assays using cho-ki, fcl (foetal calf lung), vero, hela and cef (chicken embryo fibroblast) cells. the toxic effects observed were cell rounding and death. extracts from almost all c. jejuni and c. coli strains were toxic to both cho-ki and fcl cells and 69.0% of c. jejuni isolates and ... | 1992 | 1313623 |
| in vitro activity of lomefloxacin and other antimicrobials against bacterial enteritis pathogens. | lomefloxacin is a new, difluoroquinolone. in this study, the in vitro activity of lomefloxacin against clinical isolates of a variety of bacterial species associated with acute diarrheal disease was determined and compared with that of ciprofloxacin, ofloxacin, amoxicillin, sulphamethoxazole, trimethoprim, tetracycline, and chloramphenicol. bacterial isolates were obtained from different geographical areas, including western europe and the united kingdom, southern europe, africa, the middle east ... | 1992 | 1319301 |
| cloning of campylobacter jejuni genes required for leucine biosynthesis, and construction of leu-negative mutant of c. jejuni by shuttle transposon mutagenesis. | campylobacter jejuni is a gram-negative pathogen responsible for diarrhoeal diseases in humans. to date, very little is known about the genetic organization and molecular biology of this microorganism. the cosmid vector phc79 was used to construct a genomic library from the total genomic dna of c. jejuni strain c31 in escherichia coli and recombinant cosmids capable of complementing the auxotrophic defect in leucine biosynthesis of e. coli hb101 were identified. three of 400 clones tested were f ... | 1992 | 1322552 |
| differentiation between thermophilic campylobacter species by species-specific antibodies. | the four species of thermophilic campylobacters, campylobacter jejuni, c. coli, c. upsaliensis and c. lari, are difficult to distinguish from each other because of their lack of reactivity in many conventional biochemical and physiological tests. those tests which do discriminate sometimes give discordant results. species-specific antibody preparations (aps), capable of discriminating between the thermophilic campylobacter species by dot-elisa, were raised by inoculation of mice with partially p ... | 1992 | 1322880 |
| [acute campylobacter jejuni enterocolitis resistant to quinolones in an hiv-positive patient]. | 1992 | 1327169 | |
| in vitro and in vivo antibacterial activities of am-1155, a new 6-fluoro-8-methoxy quinolone. | am-1155 is a new quinolone with a wide spectrum of antibacterial activity against various bacteria including anaerobes and mycoplasma pneumoniae. am-1155 was 2- to 16-fold more active than ciprofloxacin and ofloxacin against staphylococcus aureus including methicillin-resistant strains, staphylococcus epidermidis, streptococcus pneumoniae, and enterococcus faecalis; its mics for 90% of strains tested were 0.10 to 0.78 micrograms/ml. the activity of am-1155 was comparable to that of ciprofloxacin ... | 1992 | 1332587 |
| immunological cross-reactivity between outer membrane pore proteins of campylobacter jejuni and escherichia coli. | immunocrossreactivity between the major outer membrane protein (momp) of campylobacter jejuni 85h and the ompc porin of escherichia coli k-12 was observed. these results indicate that a common antigenic domain is conserved in both momp and ompc. this antigenic region is detected only after a 96 degrees c treatment suggesting that it is buried in the native conformation of the respective porins. in addition, differences were observed between the major outer membrane proteins from various c. jejun ... | 1992 | 1337053 |
| [preparation and use of fish fillet infusion as a basic medium for culturing bacteria]. | the authors present the first results on the utilization of fish infusion (ifp) as a basic medium for the cultivation of bacteria. the infusion was obtained from a common marine fish, corvina (micropogonias furnieri) according to the technique used in the preparation of beef infusion broth. streptococcus pyogenes, s. pneumoniae, neisseria meningitidis, campylobacter jejuni, escherichia coli, klebsiella pneumoniae, serratia marcescens, pseudomonas aeruginosa, staphylococcus aureus and bacillus su ... | 1992 | 1345299 |
| physical map of campylobacter jejuni tgh9011 and localization of 10 genetic markers by use of pulsed-field gel electrophoresis. | the physical map of campylobacter jejuni tgh9011 (atcc 43430) was constructed by mapping the three restriction enzyme sites sacii (ccgcgg), sali (gtcgac), and smai (cccggg) on the genome of c. jejuni by using pulsed-field gel electrophoresis and southern hybridization. a total of 25 restriction enzyme sites were mapped onto the c. jejuni chromosome. the size of the genome was reevaluated and was shown to be 1,812.5 kb. ten c. jejuni genetic markers that have been isolated in our laboratory were ... | 1992 | 1350583 |
| serotype distribution of campylobacter jejuni and campylobacter coli isolated from hospitalized patients with diarrhea in central australia. | campylobacter jejuni and/or campylobacter coli was cultured from 218 of 1,078 patients of all age groups admitted to alice springs hospital, alice springs, central australia, between july 1988 and june 1989 for treatment of diarrhea. one hundred sixty-six campylobacter colonies from 127 patients were subjected to o serotyping by using the penner typing scheme. all except 29 colonies could be serotyped. a total of 46 serotypes were identified, and the predominant serotypes were o:8, 17, o:22, o:1 ... | 1992 | 1370848 |
| serological diversity and chemical structures of campylobacter jejuni low-molecular-weight lipopolysaccharides. | low-mr lipopolysaccharides (lps) of campylobacter jejuni reference strains for serotypes o:1, o:4, o:23, and o:36 were examined through the liberation of core oligosaccharides by mild acid cleavage of the ketosidic linkage of 3-deoxy-d-manno-2-octulosonic acid residues to the lipid a moiety. the liberated oligosaccharides were examined for chemical structure by compositional analysis and methylated linkage analysis in conjunction with fast atom bombardment-mass spectrometry of permethylated olig ... | 1992 | 1370951 |
| variation of the o antigen of campylobacter jejuni in vivo. | during the course of a clinical study on patients with campylobacteriosis, three consecutive isolates of campylobacter jejuni from the same patient were sent for o-serotyping. marked differences in the specificities of the o antigens of the isolates were observed between the first and third isolates when a passive haemagglutination assay system developed for serotyping c. jejuni was used. differences in specificity were also demonstrated by immunoblots of lipopolysaccharides (lps) from proteinas ... | 1992 | 1372364 |
| biochemical and antigenic properties of the campylobacter flagellar hook protein. | the flagellar filament-hook complex was removed from campylobacter cells by shearing and was purified by differential solubilization and ultracentrifugation at ph 11 followed by cesium chloride buoyant density ultracentrifugation. flagellar filaments were then dissociated in 0.2 m glycine-hcl (ph 2.2), and purified hooks were collected by ultracentrifugation. the hooks (105 by 24 nm) each displayed a conical protrusion at the proximal end, a concave cavity at the distal end, and helically arrang ... | 1992 | 1375929 |
| in vivo production of a stable single-stranded cdna in saccharomyces cerevisiae by means of a bacterial retron. | gram-negative bacteria such as myxococcus xanthus, stigmatella aurantiaca, and escherichia coli contain retroelements called retrons. retrons consist of the msr-msd region and the gene for reverse transcriptase (rt), which are essential for the production of the branched rna-linked ms-dna (multicopy single-stranded dna). in this study, we attempted to produce msdna in the yeast saccharomyces cerevisiae. retron ec67 from e. coli, which is responsible for the production of msdna-ec67, was cloned u ... | 1992 | 1378616 |
| ribosomal rna gene restriction fragment diversity amongst lior biotypes and penner serotypes of campylobacter jejuni and campylobacter coli. | diversity based on ribosomal rna gene-restriction endonuclease digest patterns was detected amongst 42 strains of campylobacter jejuni and 18 strains of c. coli including representatives of 53 different penner serotypes. haeiii ribopatterns were coded for numerical analysis which showed that all except two were different including those of several strains of the same serotype (p2 and p20). at the 30% similarity level, four groupings were formed in the analysis of which three corresponded to c. j ... | 1992 | 1381326 |
| prevalence of antibodies against heat-stable antigens from helicobacter pylori in patients with dyspeptic symptoms and normal persons. | heat-stable antigens from helicobacter pylori were investigated for the detection of serum igg, iga and igm antibodies against h. pylori by an elisa technique. antibody titers against h. pylori were measured in 167 dyspeptic patients, of whom 96 were h. pylori positive confirmed by culture or microscopy, and in 482 controls (0-98 years). increased igg antibody titers were found significantly more often in dyspeptic patients with active chronic gastritis than in patients with normal morphology, a ... | 1992 | 1389098 |
| structures of the o chains from lipopolysaccharides of campylobacter jejuni serotypes o:23 and o:36. | lipopolysaccharides of c. jejuni serotypes o:23 and o:36 have been shown to contain structurally variable o polysaccharide chains with repeating units of four closely-related types: ----3)-beta-d-glcpnac-(1----3)-alpha-d-galp-(1----2)-6d-alpha-d-alt-h epp-(1---- , ----3)-beta-d-glcpnac-(1----3)-alpha-d-galp-(1----2)-6d-3-me-alpha-d-alt -hepp- (1----, ----3)-beta-d-glcpnac-(1----3)-alpha-d-galp-(1----2)-d-glycero-alpha-d-a lt-hepp - (1----, and ----3)-beta-d-glcpnac-(1----3)-alpha-d-galp-(1----2) ... | 1992 | 1394309 |
| mannose-resistant haemagglutination by campylobacter jejuni--a preliminary communication. | ten strains of c. jejuni each isolated respectively from patients with diarrhoea and from chicken intestine (10 strains from each source) were examined for presumptive colonization factor(s) by measuring their cell surface hydrophobicity and haemagglutination. none of the strains expressed cell surface hydrophobicity. however, 14 strains (7 from either source) showed variable haemagglutination pattern with human, sheep and rabbit erythrocytes in the presence of 0.5 per cent d-mannose. thus, mann ... | 1992 | 1398807 |
| lipid a in helicobacter pylori. | free lipid a of helicobacter pylori was characterized with regard to chemical composition, reactivity with anti-lipid a antibodies, and activity in a limulus lysate assay. the predominant fatty acids of h. pylori lipid a were 3-oh-18:0, 18:0, 3-oh-16:0, 16:0, and 14:0. hexosamine was present in amounts similar to those in campylobacter jejuni or salmonella typhimurium lipid a. the lipopolysaccharide of h. pylori contained 2-keto-3-deoxyoctonic acid, a common constituent of enterobacterial and c. ... | 1992 | 1398948 |
| human immune response to campylobacter jejuni proteins expressed in vivo. | campylobacter jejuni 81-176 grown in vivo in rabbit ileal loops expresses novel proteins that are not expressed under standard laboratory culture conditions. a new protein with a molecular mass of ca. 180 kda is expressed at 14, 24, and 48 h of infection. three other proteins, with molecular masses of ca. 66, 43, and 35 kda, are overexpressed during different phases of infection. expression of these proteins stops immediately during the first passage in laboratory media, and they do not elicit a ... | 1992 | 1399004 |
| altered synthetic response of campylobacter jejuni to cocultivation with human epithelial cells is associated with enhanced internalization. | campylobacter jejuni has been shown to bind to and enter epithelial cells in culture. the interaction of c. jejuni with int 407 epithelial cells was examined to determine whether bacterial protein synthesis is required for either binding or internalization. chloramphenicol, a selective inhibitor of bacterial protein synthesis, significantly reduced the internalization, but not binding, of c. jejuni compared with untreated controls as determined by protection from gentamicin. electrophoretic anal ... | 1992 | 1399005 |
| specific detection of campylobacter jejuni and campylobacter coli by using polymerase chain reaction. | development of a routine detection assay for campylobacter jejuni and campylobacter coli in clinical specimens was undertaken by using the polymerase chain reaction (pcr). an oligonucleotide primer pair from a conserved 5' region of the flaa gene of c. coli vc167 was used to amplify a 450-bp region by pcr. the primer pair specifically detected 4 strains of c. coli and 47 strains of c. jejuni; but it did not detect strains of campylobacter fetus, campylobacter lari, campylobacter upsaliensis, cam ... | 1992 | 1400961 |
| [in vitro antimicrobial activity of dr-3355, a new quinolone antibacterial agent, against clinical isolates of enteritis-causing bacteria]. | we determined the minimum inhibitory concentration (mic) of dr-3355, a newly developed quinolone-derivative antibacterial agent, against clinical isolates of various bacterial species from enteritis patients, and compared them with those of ofloxacin (oflx), ciprofloxacin (cpfx), nalidixic acid (na), ampicillin (abpc), kanamycin (km). mic90 of dr-3355 against 94 strains of shigella spp. and 5 strains of escherichia coli, 36 strains of salmonella spp., 22 strains of vibrio cholerae, 5 strains of ... | 1992 | 1402063 |
| [bacteremia from campylobacter jejuni in a cirrhotic patient with ascites]. | 1992 | 1405812 | |
| alcohol dehydrogenase mediated acetaldehyde production by helicobacter pylori--a possible mechanism behind gastric injury. | two standard helicobacter pylori strains showed significant cytosolic alcohol dehydrogenase activity and produced considerable amounts of acetaldehyde when incubated with an ethanol containing solution in vitro. the alcohol dehydrogenase activity of the helicobacter pylori strains was almost as high as that found in klebsiella pneumoniae and far greater than that in escherichia coli or campylobacter jejuni. the amount of acetaldehyde produced by cytosol prepared from helicobacter pylori exceeded ... | 1992 | 1406052 |
| [chemotherapy of campylobacter infections]. | a total of 600 patients with suspected alimentary food poisoning were hospitalized. the ++clinico-laboratory findings showed that 27 (4.5 per cent) of them had campylobacter infection. the cultures of campylobacter jejuni and campylobacter coli were isolated from 24 and 3 patients, respectively. the patients underwent complex pathogenetic treatment with oral rehydration saline solutions, symptomatic agents, enzymatic preparations and diet (the basic therapy) supplemented with biological bacteria ... | 1992 | 1417342 |
| competitive exclusion of campylobacters from poultry with k-bacteria and broilact. | the competitive exclusion (ce) product (broilact) which is effective against salmonellas, was found to be inactive against campylobacters. microecological concepts were applied in the search of a new competitive flora and two novel strains ('k-bacteria') were isolated. these strains resembled campylobacters but differed from them in morphology, enzyme profiles (api), cellular fatty acid profiles and when tested with a ribosomal rna hybridization probe (gene-trak). two-week laboratory trials on b ... | 1992 | 1419531 |
| simple and economical culture of campylobacter jejuni and campylobacter coli in co2 in moist air. | strains of campylobacter jejuni and c. coli representing the 18 serogroups (lior) most commonly isolated from humans in canada were grown on solid media in an atmosphere of 10% co2 in moist air, 99% relative humidity. when the growth of all 18 serogroups on mueller hinton agar in a microaerobic atmosphere (5% o2, 10% co2 and 85% n2) was compared with the growth of all 18 serogroups on the same media in 10% co2 in moist air, colony sizes were significantly larger (p less than 0.05) for strains gr ... | 1992 | 1419543 |
| a cytotonic, cholera toxin-like protein produced by campylobacter jejuni. | 1. campylobacter jejuni is a major cause of gastroenteric infection. 2. this organism appears to produce both cytotonic and cytotoxic virulence factors. 3. we report here that culture filtrates of some clinical isolates of c. jejuni induce elongation of chinese hamster ovary (cho) cells in vitro but do not cause inhibition of fluid absorption in the rat ileum. 4. these culture filtrates contain low levels of a protein which cross-reacts immunologically with the cholera toxin. 5. the cholera toxi ... | 1992 | 1424561 |
| prevalence, biotypes, plasmid profile and antimicrobial resistance of campylobacter isolated from wild and domestic animals from northeast portugal. | the incidence of campylobacter jejuni and campylobacter coli in wild and producing animals has been studied to evaluate their importance as potential reservoirs of campylobacter infection. these organisms were isolated from: 59 chicken (60.2%), 65 swine (59.1%), 31 black rats (57.4%), 61 sparrows (45.5%), 21 ducks (40.5%), 32 cows (19.5%) and 27 sheep (15.3%). biotypes, plasmid and resistance profiles were studied in order to characterize the isolates. biotypes i and ii of c. jejuni were predomi ... | 1992 | 1429305 |
| [clinical studies on the treatment of campylobacter enteritis--emergence of quinolone-resistant campylobacter jejuni after treatment with new quinolones]. | in recent years, new quinolones such as ofloxacin (oflx) and tosufloxacin (tflx) have been frequently used in the treatment of bacterial enteritis caused by unknown organisms. the agent of first choice for the treatment of campylobacter enteritis is one of the macrolides, but new quinolones are often administered accidentally to adult patients with campylobacter enteritis. we have detected quinolone-resistant strains of campylobacter jejuni (c. jejuni) after the treatment of some patients with n ... | 1992 | 1431368 |
| impact of zinc supplementation on intestinal permeability in bangladeshi children with acute diarrhoea and persistent diarrhoea syndrome. | zinc has been shown to enhance intestinal mucosal repair in patients suffering from acrodermatitis enteropathica; but the impact on mucosal integrity during acute (ad) or persistent (pd) diarrhoea is unknown. one hundred eleven children with ad and 190 with pd aged between 3 and 24 months received, randomly and blind to the investigators, either an elemental zinc supplement of 5 mg/kg body wt/day or placebo in multivitamin syrup for 2 weeks while intestinal permeability and, biochemical and anth ... | 1992 | 1432467 |
| differentiated caco-2 cells as a model for enteric invasion by campylobacter jejuni and c. coli. | a collection of 44 campylobacter isolates (37 c. jejuni and seven c. coli) from children with colitis (21 strains) or watery diarrhoea (23 strains) was analysed for toxin production, association with hela cells, and invasion of differentiated caco-2 cell cultures. there was no obvious association of clinical symptoms with species, biotype or enterotoxin production. all colitis strains and most of the isolates from watery diarrhoea were cytotoxic for chinese hamster ovary cells. measurements of b ... | 1992 | 1433253 |
| mononuclear cell response in the liver of mice infected with hepatotoxigenic campylobacter jejuni. | intragastric inoculation with hepatotoxigenic strains of campylobacter jejuni led to the death of mice during the late phase of infection. histological study disclosed a massive infiltration of mononuclear cells in the liver, mimicking intrahepatic hypersensitivity. neither enterotoxigenic nor enteroinvasive escherichia coli induced such a lesion. however, the same histopathological change was induced by injecting the hepatotoxic factor of hepatotoxigenic c. jejuni intravenously on two occasions ... | 1992 | 1433254 |
| campylobacter jejuni in pregnancy. | case notes of pregnancies with proven campylobacter jejuni infections were collected from 2 queensland teaching hospitals and reviewed. of these cases, 2 pregnancies (3 fetuses) resulted in stillbirths, 2 neonates required treatment with antibiotic therapy within 2 days of birth, while the remaining 2 pregnancies were treated at the time of the infection and were not associated with adverse outcome. maternal campylobacter infection should be actively sought for in the patient with suspected infe ... | 1992 | 1445138 |
| uncommon campylobacter species in infant macaca nemestrina monkeys housed in a nursery. | studies were conducted to characterize 18 isolates of campylobacter spp. that could not be identified as either campylobacter jejuni or c. coli. the isolates were cultured from specimens from 13 of 18 infant nonhuman primates during a prospective epidemiologic study reported previously. phenotypic tests, dna hybridization, and analysis of dna coding for rrna identified the isolates as c. butzleri (seven isolates), c. hyointestinalis (seven isolates), and c. fetus subsp. fetus or c. fetus subsp. ... | 1992 | 1452677 |
| accuracy of the e test for determining antimicrobial susceptibilities of staphylococci, enterococci, campylobacter jejuni, and gram-negative bacteria resistant to antimicrobial agents. | we compared the results of the e test mic method with the results of agar dilution susceptibility testing for 18 antimicrobial agents against 324 strains of gram-positive and gram-negative bacteria, including 99 strains of staphylococci, 101 strains of antimicrobial-resistant gram-negative bacteria, 40 strains of enterococci, and 84 isolates of campylobacter jejuni. overall agreement of mics (+/- 1 log2 dilution) was 97.3% for staphylococci, 94.6% for gram-negative bacilli, and 100.0% for entero ... | 1992 | 1452709 |
| prevalence of bacterial agents of diarrhoeal disease at the national university hospital, singapore and their resistance to antimicrobial agents. | over a 50-month period, 4,508 stool specimens from patients with diarrhoea were bacteriologically examined at the national university hospital, singapore. salmonella serotypes other than the typhoid and paratyphoid bacilli were the most common finding, being isolated in 10.8% of cases. campylobacter jejuni was unexpectedly infrequent (1.9%); aeromonas hydrophila was found in 1.8%. no other aerobic pathogen occurred in more than 1% of cases. clostridium difficile was sought only when requested, a ... | 1992 | 1455527 |
| occurrence, removal and seasonal variation of "thermophilic" campylobacters in a sewage treatment plant in italy. | monitoring of "thermophilic" campylobacters in a sewage treatment plant in bologna (italy) has shown that incoming sewage contained a most probable number of 1630 campylobacters/100 ml. the secondary treatment in activated sludge tanks reduced 98.61% of campylobacters, 95.32% of fecal coliforms, 96.46% of fecal streptococci, 93.36% of salmonellas and 93.01% and 88.29% of bod5 and cod respectively. subsequent tertiary treatment with 3 ppm of chlorine dioxide for 15 min reduced 100% of campylobact ... | 1992 | 1457031 |
| acute pancreatitis associated with campylobacter jejuni bacteremia. | 1992 | 1457641 | |
| anti-enterobacteria antibodies in psoriatic arthritis. | the occurrence of certain antibacterial antibodies was studied in the sera of 22 healthy donors (hd) and 66 patients with different diseases. the cases investigated included 22 rheumatoid arthritis (ra), 22 non-arthritic-psoriasis (nap), and 22 psoriatic arthritis (pa) patients. a complement fixation test was used with yersinia enterocolitica 0:3 type (yec), yersinia pseudotuberculosis (ypt), campylobacter jejuni (cj), and campylobacter fetus (cf) antigens; the detection of anti-chlamydia tracho ... | 1992 | 1458698 |
| structural studies of peptidoglycans in campylobacter species. | peptidoglycans (pg) from campylobacter coli, campylobacter jejuni, and campylobacter fetus were composed of muramic acid, glucosamine, alanine, glutamic acid, and diaminopimelic acid in a molar ratio of 1.1:1:1.7:1.1:09. thirty percent of the amino groups of diaminopimelic acid were involved in cross-linkages between peptides. during cultivation, c. coli and c. jejuni changed from a spiral to a coccoid form. in c. coli, we could isolate pg only from the spiral forms in yields of 0.8-1.2% by dry ... | 1992 | 1461153 |
| rapid emergence of quinolone resistance in campylobacter jejuni in patients treated with norfloxacin. | 15/60 subjects from one center, who all took part in a multicenter double-blind, placebo-controlled study to evaluate the effect of norfloxacin on acute enteritis, had norfloxacin sensitive strains of campylobacter jejuni in pre-study stool specimens. eight of the 15 subjects received active drug. in 3 of these 8, high-level quinolone resistant campylobacter strains of the same serotype as in pre-treatment samples were isolated 4-90 days after the initiation of treatment. | 1992 | 1465591 |
| erysipelas-like skin lesions associated with campylobacter jejuni septicemia in patients with hypogammaglobulinemia. | three cases are reported of hypogammaglobulinemic males with recurrent campylobacter jejuni septicemia and erysipelas-like cellulitis without diarrhoea. in one patient campylobacter jejuni grew from skin biopsy specimens. the findings in another patient were strongly suggestive of osteomyelitis caused by campylobacter jejuni. since the susceptibility of hypogammaglobulinemic patients to infection with campylobacter jejuni is probably related to a lack of serum bactericidal activity against campy ... | 1992 | 1468426 |
| [campylobacter jejuni bacteremia in patient with acquired immunodeficiency syndrome and hepatic cirrhosis]. | 1992 | 1469949 | |
| antibiotic susceptibility patterns and plasmid profile of helicobacter isolates from nigeria. | antibiotic susceptibility testing and plasmid screening of 50 local isolates of campylobacter coli and campylobacter jejuni were done. all isolates were sensitive to ofloxacin but were resistant to ampicillin, cloxacillin, penicillin, streptomycin and aztreonam. a large number of isolates were sensitive to nalidixic acid (96%), ceftriaxone (96%) and chloramphenicol (86%). it is noteworthy that nine (18%) of the isolates were resistant to each of erythromycin, 15 (30%) were found to harbour plasm ... | 1992 | 1476963 |
| antimicrobial susceptibilities of campylobacter jejuni and campylobacter coli isolated in sweden: a 10-year follow-up report. | resistance to erythromycin and doxycycline and more recently to fluoroquinolones has been reported to occur in campylobacter spp. both in vitro and in patients treated with these antibiotics. the frequency of resistance to 14 antimicrobial agents in campylobacter jejuni and campylobacter coli isolated from patients infected in sweden or abroad is described. for some agents, a comparison of susceptibility in strains of campylobacter spp. isolated in 1978 with those isolated in 1988 is made. no ge ... | 1992 | 1482158 |
| degenerate pcr primers for the amplification of fragments from genes encoding response regulators from a range of pathogenic bacteria. | many bacterial responses to environmental stimuli are mediated by response regulators which coordinately regulate genes involved in particular adaptive responses. degenerate oligonucleotide primers were used to amplify by the polymerase chain reaction (pcr), fragments from genes encoding eleven novel response regulators. sequence and phylogenetic analysis revealed that phob, phop and creb gene fragments had been amplified from yersinia enterocolitica and yersinia pseudotuberculosis, and that a c ... | 1992 | 1490612 |
| antibacterial spectrum of lactoferricin b, a potent bactericidal peptide derived from the n-terminal region of bovine lactoferrin. | a physiologically diverse range of gram-positive and gram-negative bacteria was found to be susceptible to inhibition and inactivation by lactoferricin b, a peptide produced by gastric pepsin digestion of bovine lactoferrin. the list of susceptible organisms includes escherichia coli, salmonella enteritidis, klebsiella pneumoniae, proteus vulgaris, yersinia enterocolitica, pseudomonas aeruginosa, campylobacter jejuni, staphylococcus aureus, streptococcus mutans, corynebacterium diphtheriae, list ... | 1992 | 1490908 |
| serotype of campylobacter jejuni, hla, and the guillain-barré syndrome. | 1992 | 1495517 | |
| isolation of nonchemotactic mutants of campylobacter jejuni and their colonization of the mouse intestinal tract. | three nonchemotactic mutants (d54, y14, and n74) of campylobacter jejuni were isolated from wild-type strain fum158432 by either the negative swarming or liquid gradient method with brucella broth as the attractive substance. strains d54 and y14 were isolated after mutagenesis with methyl methanesulfonate, and n74 was isolated from a nonmutagenized culture. these mutants all failed to swarm on a semisolid medium and did not show any chemotactic behavior in the hard-agar plus assay method for any ... | 1992 | 1500167 |
| iron acquisition and hemolysin production by campylobacter jejuni. | campylobacter jejuni strains were tested for their ability to acquire iron from various iron sources present in humans. hemin, hemoglobin, hemin-hemopexin, and hemoglobin-haptoglobin stimulated the growth of c. jejuni strains in low-iron medium. transferrin, lactoferrin, and ferritin were unable to provide iron to the strains tested. derivatives of the naturally transformable c. jejuni strain 81-176 were isolated on the basis of their inability to use hemin as an iron source. these mutants were ... | 1992 | 1500194 |
| campylobacter jejuni bacteraemia in children with diarrhoea in bangladesh: report of six cases. | campylobacter jejuni was isolated from blood cultures from 6 of 6,275 diarrhoeal children seeking treatment at the clinical research centre of the international centre for diarrhoeal disease research, bangladesh (icddr,b) between april 1989 and december 1990. the clinical records of these 6 children were reviewed. all children were male; 5 were less than 1-year old and were severely malnourished. five patients presented with watery diarrhoea and one with bloody diarrhoea. two children died in th ... | 1992 | 1500639 |
| characterization of two plasmids from campylobacter jejuni isolates that carry the apha-7 kanamycin resistance determinant. | two small plasmids of 11.5 and 9.5 kb, each carrying an apha-7 kanamycin phosphotransferase gene, were studied. the mics of kanamycin for the two human campylobacter jejuni isolates harboring the plasmids were 10,000 and 5,000 micrograms/ml, while the mics of amikacin were 32 and 8 micrograms/ml, respectively. the mics of gentamicin and tobramycin were less than or equal to 2 micrograms/ml for both isolates. the restriction endonuclease maps of the plasmids were similar, with the larger plasmid ... | 1992 | 1503433 |
| explosive campylobacter jejuni diarrhea in immunoproliferative small intestinal disease. | campylobacter jejuni is an infrequent cause of self limiting acute diarrheal disease in adults in the indian subcontinent. we report the occurrence of a life threatening diarrhea due to c jejuni infection in a patient with immunoproliferative small intestinal disease. we postulate that immunosuppression due to malignancy, malnutrition and cancer chemotherapy was responsible for the unusually severe diarrhea. | 1992 | 1506053 |
| a multiple logistic model for predicting the occurrence of campylobacter jejuni and campylobacter coli in water. | a multiple logistic regression model was established to predict the occurrence of campylobacter jejuni/coli, related to index bacteria such as faecal coliforms, faecal streptococci, and sulphite-reducing clostridia, in a water source in southern norway. the fitted model indicated that faecal coliforms were strong predictors for c. jejuni/coli, although the water temperature also had a strong influence on results. sulphite-reducing clostridia, faecal streptococci, and season of the year had no si ... | 1992 | 1512182 |
| [detection of campylobacter species by using polymerase chain reaction and nonradioactive labeled dna probe]. | we have detected campylobacter species which are now recognized as major pathogens of acute diarrheal disease in humans using polymerase chain reaction (pcr) and a nonradioactive labeled dna probe. diagnosis of campylobacter enteritis without doing culture from stool samples is of great benefit in the laboratory. two oligonucleotide primers (20 mer) complementary to a unique sequence of the dna encoding ribosomal rna (rrna) of campylobacter jejuni for pcr were synthesized by solid-phase phosphoa ... | 1992 | 1513035 |
| campylobacter jejuni isolated from ratites. | 1992 | 1515499 | |
| use of oligodeoxynucleotide probes to verify campylobacter jejuni as a cause of bovine abortion. | 1992 | 1515500 | |
| [acute aortic insufficiency following endocarditis due to infection with campylobacter fetus subspecies fetus]. | a 50-year-old male alcoholic addict, examined because of diarrhoea with fever was found to have campylobacter jejuni in blood and stool cultures. after administration of broad-spectrum penicillin all acute symptoms disappeared but he lost 8 kg within 3 months and his general state health gradually deteriorated. after 3 months he suddenly developed leg oedema, dyspnoea and bouts of fever up to 38.8 degrees c. a loud cardiac murmur was now heard. echocardiography demonstrated vegetations on the re ... | 1992 | 1516529 |
| campylobacter gastroenteritis in children in riyadh, saudi arabia. | campylobacter jejuni/coli (cjc) was isolated from the stools of 82 (1 per cent) of 7369 children with gastrointestinal symptoms during a 2-year period. among 1130 control children, cj was isolated from the stool of one (0.09 per cent). the peak incidence of cjc associated gastroenteritis was in the winter. seventy-six per cent of the patients were 4 years of age and younger with the highest incidence (56 per cent) in children 2 years old and younger. the most common presenting symptoms and signs ... | 1992 | 1527809 |
| role of campylobacter jejuni as a placental pathogen. | members of the genus campylobacter are well recognised as enteric pathogens but have rarely been implicated as human placental pathogens. a case of septic abortion due to c jejuni is reported. this occurred in a previously healthy woman with a diarrhoeal illness. the presence of chorioamnionitis raises the possibility of ascending infection rather than septicaemic spread as the pathogenesis. members of the genus campylobacter have special culture requirements and their incidence as placental pat ... | 1992 | 1541701 |
| campylobacter jejuni enteritis mistaken for ulcerative colitis. | campylobacter jejuni is the most common bacterial cause of gastroenteritis and is often missed by routine stool cultures. patients may present with a clinical syndrome and endoscopic findings that are similar to acute ulcerative colitis. ciprofloxacin is currently the recommended antibiotic therapy. | 1992 | 1541961 |
| [fever, headache, diarrhea]. | a 26-year-old man suddenly developed fever, headache, pain in the lower extremities, diarrhoea, and lymphadenopathy on the way back from thailand. subsequently, leukopenia, thrombocytopenia, coagulation abnormality and a morbilliform exanthema were noted. with symptomatic treatment the patient could be dismissed in good health after nine days. the diagnosis of dengue and campylobacter jejuni/coli infection could be verified serologically by a rising antibody titer and by a positive stool culture ... | 1992 | 1542765 |
| campylobacter enteritis in saudi arabia. | a 12-month survey on the incidence of campylobacter infection in 1217 patients with diarrhoea was carried out in jeddah, saudi arabia. campylobacters were isolated from 55 (4.5%) patients, second in prevalence to salmonellas (6.2%). shigellas were isolated from 4.2% of patients. campylobacter isolation rates were high in children of all ages, as well as in young adults (36.5% of all isolates were from adults aged 20-39 years). isolation rates peaked in september and november. analysis of the res ... | 1992 | 1547840 |
| campylobacter species as a cause of diarrhoea in children in calcutta. | from 1985 to 1988, 857 children (aged between 1 day and 60 months) admitted to hospital with diarrhoea and 241 controls (aged between 5 days and 60 months) were examined for campylobacters and other enteric pathogens by means of conventional methods. the difference between the isolation rates of campylobacters in those cases in which no other enteric pathogen was found (4.8%) and controls (6.2%) was not significant (p greater than 0.05). strains of campylobacter jejuni/coli were isolated through ... | 1992 | 1548418 |
| in vitro binding of campylobacter jejuni/coli outer membrane preparations to int 407 cell membranes. | outer membrane fractions (oms) of nine campylobacter (c.) jejuni and two c. coli strains belonging to different serovars, from human and various animal origins, were extracted by treatment with sodium n-lauryl sarcosinate. using n-octyl-beta-d-glucopyranoside a 42-kda protein and a flagella-enriched fraction were obtained. the capacity of the crude bacterial om preparations, the purified 42-kda protein and the flagella to bind to membranes of the human embryonic intestinal cell line int 407 was ... | 1992 | 1549070 |
| the gene for the s7 ribosomal protein of chlamydia trachomatis: characterization within the chlamydial str operon. | the prokaryotic ribosomal operon, str, contains open reading frames for the two elongation factors, elongation factor g (ef-g) and elongation factor tu (ef-tu), and ribosomal proteins s7 and s12. the dna sequence and predicted amino acid sequence for s7 from chlamydia trachomatis are presented and compared with homologues from other prokaryotes. also, the relationship of the s7 gene to the open reading frames for ribosomal protein s12 and ef-g is described. significant amino acid homology is als ... | 1992 | 1552847 |
| [myocarditis and pericarditis in connection with campylobacter jejuni infection]. | we describe a case of myo/pericarditis related to infection with c. jejuni. the microbe was repeatedly isolated from faeces and the patient had specific iga, igm and igg antibodies, detected in serum samples by means of a dig-elisa method. the condition is rare and the pathogenesis unclear. the case described may be the result of a primary infection or a reactive immune response. | 1992 | 1553694 |
| [multicausal infectious respiratory tract disease of young fattening turkeys]. | the outbreak of the disease occurred in a large multiple-age farm with about 50,000 meat turkeys, where groups of 6-8000 one-day-old birds were stalled up every 14 days. all the turkey poults housed were affected mostly in the 1.-3. week of the life. the respiratory disease spread rapidly within the flocks and were characterised clinically by inclination of huddle, ruffled feathers, anorexia, stunted growth, swelling of the infraorbital sinus and nasal discharge. the clinical apparent disease la ... | 1992 | 1559465 |
| a one-year study of enteric campylobacter infections in singapore. | a total of 7344 inpatients with diarrhoea were investigated for campylobacter infections in singapore over one year. campylobacter species were recovered from 1.2% of diarrhoeal stools; 70.3% of the 91 campylobacters were from children under 5 years of age. further identification of these isolates showed that 89% were campylobacter jejuni and 10.9% were c. coli, and a high level of resistance to erythromycin was observed among them. concomitant isolation of salmonella species or shigella species ... | 1992 | 1560479 |
| bilateral abducens paresis following campylobacter jejuni enteritis. | 1992 | 1569314 | |
| campylobacter jejuni--an unusual cause of infectious arthritis. | 1992 | 1570263 | |
| campylobacter enteritis in portugal: epidemiological features and biological markers. | from 1984 to 1989, stool samples from 2811 gastroenteritis cases were examined for the presence of campylobacter jejuni and c. coli, salmonella, shigella and yersinia species. isolation rates were: campylobacter jejuni and c. coli, 5.3%, salmonella spp., 14.8%, shigella spp., 4.6% and yersinia enterocolitica, 1.1%. age group distribution analysis shows a higher campylobacter isolation rate in children under one year of age. seasonal distribution revealed a peak incidence in winter as in other me ... | 1992 | 1572427 |
| [campylobacter jejuni diarrhea and myopericarditis]. | 1992 | 1576305 | |
| phagocyte killing of campylobacter jejuni in relation to oxidative activation. | when studying the interaction between campylobacter jejuni and human neutrophils, we found that four different clinical isolates showed a great variability in this association. also the ability to induce neutrophil production of oxidative metabolites, measured as chemiluminescence (cl), differed between the strains. surprisingly, strain 1, which showed weak interaction with neutrophils and high resistance to killing, induced the highest cl response. all strains evoked an intracellular cl respons ... | 1992 | 1586479 |
| characterization of a 25,000-dalton helicobacter pylori protein, cross-reacting with a campylobacter jejuni protein. | extract obtained by ultrasonic disruption of helicobacter pylori bacteria contained a protein with subunit molecular mass of 25 kd which bound antibodies in sera from patients with h. pylori-associated disease. the protein was purified by gel permeation and elution from sds-polyacrylamide gel slices, and was used to raise an anti-25-kd protein-specific rabbit serum. using the antiserum in experiments, the results indicated the following: the protein exists as covalently linked dimers (45 kd) of ... | 1992 | 1586485 |
| a new case of peritonitis due to campylobacter jejuni in capd. | 1992 | 1586699 | |
| conjugal transfer of antibiotic resistances and plasmids from campylobacter jejuni clinical isolates. | six campylobacter jejuni clinical isolates were examined for the occurrence of plasmids in association with antibiotic resistances as well as conjugal transfer. all the isolates were found to carry three similar plasmids of 78 kb, 12.6 kb and 3.3 kb in size. multiple resistance to at least three of the antibiotics tested was observed with resistance to tetracycline most common. en bloc transfer of donor resistances at frequencies ranging from 10(-8) to 10(-4) were seen in all but one of the isol ... | 1992 | 1587459 |
| cross-reactive proteins of borrelia burgdorferi. | the specificity of serological tests for lyme borreliosis is impaired by cross-reacting antibodies. in order to select antigens for more specific tests, specific and cross-reactive proteins of borrelia burgdorferi must be identified. therefore, to analyze cross reactions of borrelia burgdorferi with other bacteria, rabbit immune sera against heterologous bacteria (borrelia hermsii, treponema pallidum, treponema phagedenis, leptospira interrogans (serogroup grippotyphosa), neisseria meningitidis, ... | 1992 | 1597198 |
| age distribution of diarrhoeal and healthy children infected with campylobacter jejuni. | the prevalence of infection with campylobacter jejuni in diarrhoeal and healthy children (age less than 7 years old) was investigated from 1 march to 31 may 1988 in chengdu city, china. the isolation rate in diarrhoeal children (11.88%) was higher than in healthy children (4.62%) (p less than 0.005). in both diarrhoeal and healthy children, infants (less than 12 months of age) had lower rates of infection than older children (p less than 0.005 and p less than 0.05 respectively). the frequency of ... | 1992 | 1597881 |
| extended phage-typing scheme for campylobacter jejuni and campylobacter coli. | the extended phage-typing scheme described for campylobacter jejuni and campylobacter coli has established 46 different phage types using 19 typing phages. altogether 754 campylobacter isolates, 672 c. jejuni and 82 c. coli, isolated from human and non-human sources received from 17 different countries were phage-typed. overall, 80.6% of the total isolates were typable. among typable strains, 9 phage types (3, 5, 10, 11, 18, 19, 23, 26 and 44) represented 57.0% of the strains, 21.3% of the strai ... | 1992 | 1601075 |
| seroepidemiology of helicobacter pylori infection in vegans and meat-eaters. | an enzyme-linked immunosorbent assay has been used to diagnose serologically the prevalence of helicobacter pylori infection in asian life-long vegans. there was no difference in the seropositivity between these individuals and a group of age- and sex-matched asian meat-eaters, indicating the meat consumption is not a risk factor for h. pylori infection. however, both asian groups had a higher prevalence of infection than age- and sex-matched caucasian meat-eaters. additionally, the asian indivi ... | 1992 | 1601079 |
| microbic superinfection in relapse of inflammatory bowel disease. | to assess the association between symptomatic relapse of inflammatory bowel disease (ibd) and superinfection with enteropathogenic microorganisms, we determined prospectively the incidence of infections with enteropathogenic bacteria, protozoa, and helminths in patients with confirmed longstanding ibd. sixty-four patients with ibd (49 with crohn's disease [cd] and 15 with ulcerative colitis [uc]) were consecutively enrolled in the study when relapse occurred. multiple biopsies for histological a ... | 1992 | 1607606 |
| rectal bleeding caused by campylobacter jejuni in a neonate. | 1992 | 1608692 | |
| reduction of campylobacter jejuni colonization of chicks by cecum-colonizing bacteria producing anti-c. jejuni metabolites. | cecum-colonizing bacteria were isolated from campylobacter jejuni-free white leghorn (gallus domesticus) laying hens and screened for the ability to produce anti-c. jejuni metabolites. nine isolates were obtained that possessed this characteristic. the peroral administration of the nine isolates as a mixture (ca. 10(9) per chick) to 1-day-old chicks was followed 1 week later by peroral inoculation of campylobacter jejuni (ca. 10(9) per chick) to determine if the cecal isolates could protect chic ... | 1992 | 1610187 |
| occurrence of thermotolerant campylobacters in fresh vegetables sold at farmers' outdoor markets and supermarkets. | a total of 1564 fresh samples of 10 vegetable types from two different retail levels (533 samples from farmers' outdoor markets and 1031 samples from supermarkets) were surveyed for the occurrence of thermotolerant campylobacters. in samples from the outdoor markets, campylobacters were detected on six types of vegetables; the detection rates were spinach, 3.3; lettuce, 3.1; radish, 2.7; green onions, 2.5; parsley, 2.4; and potatoes, 1.6%. campylobacter jejuni was the predominant species (88%), ... | 1992 | 1611556 |
| occurrence of campylobacter spp. in young gulls, duration of campylobacter infection and reinfection by contact. | two groups of three week old herring gulls (larus argentatus) were held to observe the carrier state with campylobacter. all 27 birds of group i excreted campylobacter jejuni biotype iii when they were caught from their colony. four weeks later all but one were negative, indicating that the carrier state lasts until about the seventh week of life, with self-elimination if infection with another campylobacter species is prevented by housing in a closed environment as in this study. only one bird ... | 1992 | 1621473 |
| [development of genetic and molecular approaches for the diagnosis and the study of the pathogenic power of helicobacter pylori, agent of inflammatory gastric diseases]. | helicobacter pylori (h. pylori) is a small gram negative bacillus, recently discovered, found in the stomach of patients with active chronic gastritis and duodenal ulcers. production of a potent urease has been described as a trait common to all h. pylori so far isolated. to clarify the role of urease in the pathogenic process, as well as to engineer genetic tools useful for the diagnosis of h. pylori, we cloned the genes responsible for urease activity. a genomic library was constructed in esch ... | 1992 | 1622109 |
| study on the epidemiology and control of campylobacter jejuni in poultry broiler flocks. | broiler flocks are frequently infected with campylobacter jejuni. the origin of the infection is still unclear. the question of whether colonization of flocks results from transmission of c. jejuni from breeder flocks to progeny (vertical transmission) or from environmental sources (horizontal transmission) remains to be answered. therefore, in this study samples were taken from successive broiler flocks in two broiler houses (house a on farm a and house b1 on farm b) as well as from the environ ... | 1992 | 1622265 |
| campylobacter jejuni non-culturable coccoid cells. | the behaviour of campylobacter jejuni in the environment is poorly documented. rapid loss of viability on culture media is reported. this phenomenon is associated with the development of so-called coccoid cells. it has been suggested that these cells can be infective to animals and man. results obtained with atp-measurements of coccoid cells and direct viable count (dvc) support this hypothesis. introduction of coccoid cells into simulated gastric, ileal and colon environments did not result in ... | 1992 | 1622752 |
| distribution and numbers of campylobacter in newly slaughtered broiler chickens and hens. | if campylobacter is present in the intestinal tract, broiler carcasses become extensively contaminated during the slaughter process. to determine the distribution and numbers of campylobacter jejuni/coli in newly slaughtered broiler chickens and hens, a total of 100 birds from six campylobacter-positive flocks were sampled at three swedish processing plants. campylobacters were isolated in 89% of neck skins, 93% of peritoneal cavity swab samples and in 75% of subcutaneous samples. muscle samples ... | 1992 | 1622758 |
| outer membrane components of campylobacter hyointestinalis. | outer membranes were isolated, by sodium lauryl sulphate extraction, from the american type strain, five australian, and four english isolates of campylobacter hyointestinalis. on sds-page examination, the protein profiles of seven strains (including the type strain) were similar, and were dominated by two major proteins of 47 and 50 kda. three other isolates had unique major protein profiles. the largest of these proteins was heat-modifiable in these isolates, and in the type strain. the flagel ... | 1992 | 1624127 |
| variation in antigenicity and molecular weight of campylobacter coli vc167 flagellin in different genetic backgrounds. | campylobacter coli vc167 has been shown to undergo a reversible flagellar antigenic variation between antigenic type 1 (t1) and antigenic type 2 (t2). vc167 contains two flagellin genes, and the products of both genes are incorporated into a complex flagellar filament in both antigenic types. although there are only minor amino acid changes in the flagellins expressed by t1 and t2 cells, the two antigenic types of flagellins can be distinguished by differences in apparent m(r) on sodium dodecyl ... | 1992 | 1624417 |
| [serological studies on campylobacter jejuni/coli: establishment of national reference system for serological typing in japan]. | in order to establish a national reference system for campylobacter serotyping in japan, 7 local institutes of public health collaborated to prepare 30 serogrouping antisera including 26 antisera of lior's serogrouping system and 4 antisera of tck serogrouping system which was developed by the tokyo metropolitan research laboratory of public health. a total of 603 strains (92.2%) out of 654 isolates from 23 outbreaks of c. jejuni throughout japan were serogrouped by the 30 antisera. out of 1,198 ... | 1992 | 1624822 |
| production of enterotoxin and cytotoxin in campylobacter jejuni strains isolated in costa rica. | the production of toxins by 79 strains of campylobacter jejuni isolated in costa rica from children with campylobacter-induced diarrhoea (44 strains) and from chickens (35 strains) was studied. an enterotoxic effect giving a rounding of mouse adrenocortical tumour (y1) cells, which could be neutralised with antitoxin against escherichia coli heat-labile enterotoxin, was detected in supernates from 16 (62%) of 26 strains from children with watery diarrhoea, in 5 (28%) of 18 strains from children ... | 1992 | 1625311 |
| factors that influence the interaction of campylobacter jejuni with cultured mammalian cells. | although campylobacter jejuni is now recognised as a common enteric pathogen, the mechanisms by which this organism produces enteritis remain ill-defined. it has been proposed that its abilities to adhere to and enter epithelial cells represent properties essential to virulence. however, the characteristics of these interactions and factors that may influence the association of c. jejuni with epithelial cells are incompletely described. we have determined that the ability of c. jejuni to bind to ... | 1992 | 1625313 |
| pathogenicity of campylobacter jejuni for turkeys and chickens. | a campylobacter jejuni isolate obtained from a turkey liver, designated c101, and a c. jejuni isolate obtained from the feces of a chicken, designated c111, were used to inoculate their respective hosts. isolate c101 depressed weight gain by 20% when inoculated into newly hatched poults or 4-day-old poults. it also caused death, hepatic necrosis, and generalized hemorrhages in turkey embryos. the chicken-derived isolate, c111, did not reduce weight gain in newly hatched chicks, but it did induce ... | 1992 | 1627109 |
| [an acute axonal polyneuropathy affecting intrinsic hand muscles following campylobacter infection--a case report]. | a 24-year-old carpenter had the shakes and fever on march 13, 1990. he suffered from watery diarrhea on march 14 and 15. he left muscle weakness in his thumbs and fingers when he drove nails with a hammer on march 24. the weakness reached maximum by the 3rd day of illness. he was admitted to our hospital on day 4. neurological examination revealed symmetrical weakness localized in the intrinsic hand muscles (mrc grade 2-4). the deep tendon reflexes were preserved. sensation was intact except for ... | 1992 | 1628453 |