Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| reducing the cost and assessing the performance of a novel adult mass-rearing cage for the dengue, chikungunya, yellow fever and zika vector, aedes aegypti (linnaeus). | the widespread emergence of resistance to insecticides used to control adult aedes mosquitoes has made traditional control strategies inadequate for the reduction of various vector populations. therefore, complementary vector control methods, such as the sterile insect technique, are needed to enhance existing efforts. the technique relies on the rearing and release of large numbers of sterile males, and the development of efficient and standardized mass-rearing procedures and tools is essential ... | 2019 | 31553724 |
| liaisons dangereuses: cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito aedes aegypti from brazil and french guiana. | in recent years, south america has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and zika. aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. | 2019 | 31553370 |
| aedes spp. and their microbiota: a review. | aedes spp. are a major public health concern due to their ability to be efficient vectors of dengue, chikungunya, zika, and other arboviruses. with limited vaccines available and no effective therapeutic treatments against arboviruses, the control of aedes spp. populations is currently the only strategy to prevent disease transmission. host-associated microbes (i.e., microbiota) recently emerged as a promising field to be explored for novel environmentally friendly vector control strategies. in ... | 2019 | 31551973 |
| non-canonical transcriptional regulation of heme oxygenase in aedes aegypti. | heme oxygenase (ho) is a ubiquitous enzyme responsible for heme breakdown, which yields carbon monoxide (co), biliverdin (bv) and ferrous ion. here we show that the aedes aegypti heme oxygenase gene (aeho - aael008136) is expressed in different developmental stages and tissues. aeho expression increases after a blood meal in the midgut, and its maximal transcription levels overlaps with the maximal rate of the further modified a. aegypti biglutaminyl-biliverdin (aebv) pigment production. ho is a ... | 2019 | 31551499 |
| conspecific and allospecific larval extracts entice mosquitoes to lay eggs and may be used in attract-and-kill control strategy. | one of the strategies of integrated vector management is to lure gravid mosquitoes for surveillance purposes or to entice them to lay eggs in water containing toxins that kill the offspring (attract-and-kill or trap-and-kill). typically, the major challenge of this approach is the development of a lure that stimulates oviposition plus a toxin with no deterrent effect. bacillus thuringiensis var. israelensis (bti) satisfies the latter criterion, but lures for these autocidal gravid traps are sore ... | 2019 | 31551447 |
| serine hydroxymethyltransferase controls blood-meal digestion in the midgut of aedes aegypti mosquitoes. | female aedes aegypti mosquitoes are vectors of arboviruses that cause diverse diseases of public health significance. blood protein digestion by midgut proteases provides anautogenous mosquitoes with the nutrients essential for oocyte maturation and egg production. midgut-specific mir-1174 affects the functions of the midgut through its target gene serine hydroxymethyltransferase (shmt). however, less is known about shmt-regulated processes in blood digestion by mosquitoes. | 2019 | 31551071 |
| rapid screening of aedes aegypti mosquitoes for susceptibility to insecticides as part of zika emergency response, puerto rico. | in response to the 2016 zika outbreak, aedes aegypti mosquitoes from 38 locations across puerto rico were screened using centers for disease control and prevention bottle bioassays for sensitivity to insecticides used for mosquito control. all populations were resistant to pyrethroids. naled, an organophosphate, was the most effective insecticide, killing all mosquitoes tested. | 2019 | 31538919 |
| black soldier fly (hermetia illucens) larvae powder as a larval diet ingredient for mass-rearing aedes mosquitoes. | the mass production of mosquitoes is becoming more wide-spread due to the increased application of the sterile insect technique (sit) and other genetic control programmes. due to the variable availability and high cost of the bovine liver powder (blp) constituent of many current larval diets, there is an urgent demand for new ingredients in order to support sustainable and efficient mosquito production while reducing rearing cost, without affecting the quality of the insects produced. two black ... | 2019 | 31535969 |
| pyriproxyfen, a juvenile hormone analog, damages midgut cells and interferes with behaviors of aedes aegypti larvae. | juvenile hormone analogs (jha) are known to interfere with growth and biosynthesis of insects with potential for insecticide action. however, there has been comparatively few data on morphological effects of jha on insect organs. to determine pyriproxyfen effects on aedes aegypti larvae, we conducted toxicity, behavioral bioassays and assessed ultrastructural effects of pyriproxyfen on midgut cells. a. aegypti larvae were exposed in aqueous solution of pyriproxyfen lc50 concentrations and evalua ... | 2019 | 31534837 |
| oviposition site attraction of aedes albopictus to sites with conspecific and heterospecific larvae during an ongoing invasion in medellín, colombia. | aedes aegypti and aedes albopictus are two globally invasive vectors with similar ecological niches. encounters between them can result in either competitive exclusion or stable co-existence, but it is unclear what drives these variable outcomes. larval competition in favor of ae. albopictus is a main hypothesis for the competitive exclusion of ae. aegypti observed in some regions. however, the role of oviposition preference in determining the degree of competitive larval interactions in the fie ... | 2019 | 31533784 |
| vector competence: what has zika virus taught us? | the unprecedented outbreak of zika virus (zikv) infection in the americas from 2015 to 2017 prompted the publication of a large body of vector competence data in a relatively short period of time. although differences in vector competence as a result of disparities in mosquito populations and viral strains are to be expected, the limited competence of many populations of the urban mosquito vector, aedes aegypti, from the americas (when its susceptibility is viewed relative to other circulating/r ... | 2019 | 31533267 |
| the genetic structure of aedes aegypti populations is driven by boat traffic in the peruvian amazon. | in the americas, as in much of the rest of the world, the dengue virus vector aedes aegypti is found in close association with human habitations, often leading to high population densities of mosquitoes in urban settings. in the peruvian amazon, this vector has been expanding to rural communities over the last 10-15 years, but to date, the population genetic structure of ae. aegypti in this region has not been characterized. to investigate the relationship between ae. aegypti gene flow and human ... | 2019 | 31532762 |
| update on the distribution of aedes albopictus (diptera: culicidae) in misiones, argentina. | the asian tiger mosquito ( aedes albopictus, diptera: culicidae) has spread rapidly in the last 30 years from its native region in southeast asia. in argentina, studies on its potential distribution suggest that this species could be found in temperate zones of the province of buenos aires. however, since its initial detection in 1998 ae. albopictus is bounded to the subtropical province of misiones. to evaluate the presence and abundance of ae. albopictus in the northeast of argentina, we preli ... | 2019 | 31531624 |
| a rare presentation of coinfection: dengue virus and hepatitis a virus. | dengue fever caused by dengue virus is a common tropical infection transmitted by the mosquitos aedes aegypti and aedes albopictus. four strains of the genus flavivirus is responsible for the epidemics of varying severity. hepatitis a caused by hepatitis a virus is spread by faecal-oral route. the culprit virus is a hepatovirus. coinfection with dengue virus and hepatitis a virus is rare and is a diagnostic as well as management challenge to the medical professional. we report a patient who pres ... | 2019 | 31531251 |
| environmental suitability for aedes aegypti and aedes albopictus and the spatial distribution of major arboviral infections in mexico. | this paper discusses a comparative geographic distribution of aedes aegypti and aedes albopictus mosquitoes in mexico, using environmental suitability modeling and reported cases of arboviral infections. | 2019 | 31528740 |
| host serum iron modulates dengue virus acquisition by mosquitoes. | a blood meal is the primary route through which mosquitoes acquire an arbovirus infection. blood components or their metabolites may regulate the susceptibility of mosquitoes to arboviruses. here we report that serum iron in human blood influences dengue virus acquisition by mosquitoes. dengue virus acquisition by aedes aegypti was inversely correlated with the iron concentration in serum from human donors. in a mouse-mosquito acquisition model, iron supplementation reduced dengue virus prevalen ... | 2019 | 31527795 |
| human odour coding in the yellow fever mosquito, aedes aegypti. | insects use their olfactory systems to obtain chemical information on mating partners, oviposition sites and food. the yellow fever mosquito aedes aegypti, an important vector of human infectious diseases, shows strong preference for human blood meals. this study investigated the chemical basis of host detection by characterizing the neuronal responses of antennal olfactory sensilla of female ae. aegypti to 103 compounds from human skin emanations. the effect of blood feeding on the responses of ... | 2019 | 31527631 |
| use of maldi-tof ms to identify the culturable midgut microbiota of laboratory and wild mosquitoes. | mosquitoes are responsible for transmitting many pathogens to humans and aedes aegypti, aedes albopictus and culex quinquefasciatus are important vectors in the world. the microbiota plays an important role in developmental studies that involve impacts on the biological cycle of mosquitoes and vector control strategies. in this study, the aim was to understand the environment plays in the microbiota culturable diversity of aedes aegytpi, aedes albopictus and culex quinquefasciatus. midgut of stu ... | 2019 | 31525322 |
| toxic effect of essential oil and its compounds isolated from sphaeranthus amaranthoides burm. f. against dengue mosquito vector aedes aegypti linn. | aedes aegypti is a major mosquito vector that can transfer many deadly diseases such as dengue, chikungunya, zika, and yellow fever viruses. due to the developing resistance among the vector populations by the application of chemical insecticides, alternative eco-friendly vector management strategies are being focused. in this aspect, the present study was carried out to evaluate the mosquitocidal potentials of essential oil of sphaeranthus amaranthoides (eo-sa). eo-sa was found to be effective ... | 2019 | 31519251 |
| cyp-mediated resistance and cross-resistance to pyrethroids and organophosphates in aedes aegypti in the presence and absence of kdr. | aedes aegypti thrives in urban environments and transmits several debilitating human viral diseases. thus, our ability to control this mosquito species in endemic areas is of utmost importance. the use of insecticides, mostly pyrethroids and organophosphates (ops), has long been the primary means of controlling a. aegypti, but widespread insecticide resistance has emerged. the two main mechanisms of pyrethroid resistance in a. aegypti are cyp-mediated detoxification and mutations in the target s ... | 2019 | 31519246 |
| chemical composition of the essential oil and n-hexane extract of stachys tmolea subsp. tmolea boiss., an endemic species of turkey, and their mosquitocidal activity against dengue vector aesdes aegypti. | stachys tmolea subsp. tmolea boiss. is endemic to turkey and is a species of the genus stachys l. which is one of the largest genera of the family lamiaceae with about 300 species. the aims of this study were to examine the chemical composition of the essential oil and n-hexane extract of s. tmolea subsp. tmolea as natural sources of insecticidal activity against the dengue vector, aedes aegypti. analysis of the essential oil by gc-fid and gas chromatography-mass spectrometry (gc-ms) systems ide ... | 2019 | 31516330 |
| temporal pattern of mutations in the knockdown resistance (kdr) gene of aedes aegypti mosquitoes sampled from southern taiwan. | aedes mosquitoes are the principal dengue vector in taiwan, where the use of insecticides is a key element in the national control strategy. however, control efforts are constrained by the development of resistance to most insecticides, including pyrethroids. in this study, mutations in the voltage-gated sodium channel (vgsc) gene resulting in knockdown resistance (kdr) were examined in aedes aegypti. fragments of the vgsc gene were polymerase chain reaction (pcr)-amplified followed by restricti ... | 2019 | 31516108 |
| transgenic aedes aegypti mosquitoes transfer genes into a natural population. | in an attempt to control the mosquito-borne diseases yellow fever, dengue, chikungunya, and zika fevers, a strain of transgenically modified aedes aegypti mosquitoes containing a dominant lethal gene has been developed by a commercial company, oxitec ltd. if lethality is complete, releasing this strain should only reduce population size and not affect the genetics of the target populations. approximately 450 thousand males of this strain were released each week for 27 months in jacobina, bahia, ... | 2019 | 31506595 |
| hold your breath - differential behavioral and sensory acuity of mosquitoes to acetone and carbon dioxide. | host seeking in the yellow fever mosquito, aedes aegypti, and the african malaria mosquito, anopheles coluzzii, relies on specific and generic host-derived odorants. previous analyses indicate that the behavioral response of these species depends differentially on the presence of carbon dioxide (co2) and other constituents in human breath for activation and attraction. in this study, we use a flight tube assay and electrophysiological analysis to assess the role of acetone, a major component of ... | 2019 | 31887129 |
| odorant ligands for the co2 receptor in two anopheles vectors of malaria. | exhaled co2 is an important host-seeking cue for anopheles mosquitoes, which is detected by a highly conserved heteromeric receptor consisting of three 7-transmembrane proteins gr22, gr23, and gr24. the co2 receptor neuron has been shown to also respond sensitively to a variety of odorants in aedes aegypti. the detection of co2 is important for upwind navigation and for enhancing the attraction to body heat as well as to skin odorants. the orthologs of the co2 receptor proteins are present in ma ... | 2019 | 30796292 |
| nix is a male-determining factor in the asian tiger mosquito aedes albopictus. | the initial signal that governs sex determination is highly variable among insects. a homolog of nix, the male-determining factor in aedes aegypti, was previously found in the asian tiger mosquito ae. albopictus. here we show that the ae. albopictus nix (aalnix) is more complex in gene structure and splice isoforms than its ae. aegypti homolog (aaenix). aalnix shows a similar transcription profile compared to aaenix. crispr/cas9-mediated knockouts of aalnix in vivo and in the ae. albopictus c6/3 ... | 2019 | 31901476 |
| geographical distribution of aedes aegypti aegypti and aedes aegypti formosus (diptera: culicidae) in kenya and environmental factors related to their relative abundance. | the mosquito aedes aegypti (l.) is the primary vector of various infectious viruses and is typified by a polymorphic color and abundance of white scales on the body. it has been conventionally separated into two subspecies, ae. aeg. formosus (walker) (aaf) and ae. aeg. aegypti (l.) (aaa), with aaf considered a 'sylvan' form and aaa a 'domestic' form. because the two subspecies show different susceptibilities to dengue viruses it is important to understand their distribution. in this study, we co ... | 2019 | 31815285 |
| vgsc-interacting proteins are genetically associated with pyrethroid resistance in aedes aegypti. | association mapping of factors that condition pyrethroid resistance in aedes aegypti has consistently identified genes in multiple functional groups. toward better understanding of the mechanisms involved, we examined high throughput sequencing data (hts) from two aedes aegypti aegypti collections from merida, yucatan, mexico treated with either permethrin or deltamethrin. exome capture enrichment for coding regions and the aaegl5 annotation were used to identify genes statistically associated w ... | 2019 | 30695054 |
| susceptibility profile of aedes aegypti l. (diptera: culicidae) from montclair, california, to commonly used pesticides, with note on resistance to pyriproxyfen. | the peridomestic anthropophilic aedes aegypti l. (diptera: culicidae) is originated from the wild zoophilic subspecies aedes aegypti formosus in sub-saharan africa, and currently has a broad distribution in human-modified environments of the tropics and subtropics worldwide. in california, breeding populations were initially detected in 2013 in the cities of fresno, madera, and san mateo, and now can be found in 188 cities of 12 counties in the state. recent genetic studies suggest that this spe ... | 2019 | 30810751 |
| hyalodendrins a and b, new decalin-type tetramic acid larvicides from the endophytic fungus hyalodendriella sp. ponipodef12. | two new decalin/tetramic acid hybrid metabolites, hyalodendrins a (1) and b (2) were isolated from plant endophytic fungus hyalodendriella sp. ponipodef12. the structures of the new compounds were elucidated by analysis of the spectroscopic data, including nmr, hrms and ecd, and by chemical conversion. compounds 1 and 2 were phomasetin analogues, and both showed potent larvicidal activity against the fourth-instar larvae of aedes aegypti with the median lethal dose (lc50) values of 10.31 and 5.9 ... | 2019 | 31892246 |
| co-occurrence of kdr mutations v1016i and f1534c and its association with phenotypic resistance to pyrethroids in aedes aegypti (diptera: culicidae) populations from costa rica. | aedes aegypti (linnaeus, 1762) is considered the most important mosquito vector species for several arboviruses (e.g., dengue, chikungunya, zika) in costa rica. the primary strategy for the control and prevention of aedes-borne diseases relies on insecticide-based vector control. however, the emergence of insecticide resistance in the mosquito populations presents a significant threat to these prevention actions. the characterization of the mechanisms driving the insecticide resistance in ae. ae ... | 2019 | 31891404 |
| risk of dengue in central africa: vector competence studies with aedes aegypti and aedes albopictus (diptera: culicidae) populations and dengue 2 virus. | dengue is the most important mosquito-borne diseases worldwide but was considered scarce in west-central africa. during the last decade, dengue outbreaks have increasingly been reported in urban foci in this region suggesting major epidemiological changes. however, in central africa where both vectors, aedes aegypti and aedes albopictus are well established, the role of each species in dengue transmission remains poorly investigated. | 2019 | 31887138 |
| diverse sensitivities of trpa1 from different mosquito species to thermal and chemical stimuli. | temperature and odors profoundly affect the behavior of animals. transient receptor potential channel, subfamily a, member 1 (trpa1) functions as a polymodal nociceptor for sensing both vital environmental cues in insects. mosquitoes are recognized as disease vectors, and many efforts have been devoted to investigations of their host-seeking behaviors and repellents. however, the physiological characteristics of mosquito trpa1 have not been systematically studied. we identified multiple alternat ... | 2019 | 31882848 |
| spatial risk distribution of dengue based on the ecological niche model of aedes aegypti (diptera: culicidae) in the central mexican highlands. | dengue is the most important viral disease transmitted by mosquitoes, predominantly aedes (stegomyia) aegypti (l.) (diptera:culicidae). forty percent of the world's population is at risk of contracting the disease, and a large area of mexico presents suitable environmental conditions for the life cycle of ae. aegypti. in particular, the central mexican highlands have a high population density, increasing the risk of transmission and propagation of dengue. in the present study, the potential dist ... | 2019 | 31880769 |
| effect of d-allethrin aerosol and coil to the mortality of mosquitoes. | commercial insecticides were widely used by communities to control the mosquito population in their houses. d-allethrin is one of insecticide ingredients widely distributed in two different concentrations namely 0.15% of aerosol and 0.3% of coil formulations. we aimed to understand the mortality of indoor mosquitoes after being exposed to d-allethrin 0.15% (aerosol) and 0.3% (coil) formulations. | 2019 | 31879666 |
| clustering of zika viruses originating from different geographical regions using computational sequence descriptors. | in this report we consider a data set, which consists of 310 zika virus genome sequences taken from different continents, africa, asia and south america. the sequences, which were compiled from genbank, were derived from the host cells of different mammalian species (simiiformes, aedes opok, aedes africanus, aedes luteocephalus, aedes dalzieli, aedes aegypti, and homo sapiens). for chemometrical treatment the sequences have been represented by sequence descriptors derived from their graphs or ne ... | 2019 | 31878862 |
| dirofilaria and wolbachia in mosquitoes (diptera: culicidae) in central european russia and on the black sea coast. | dirofilariasis is endemic in russia, as well as in many other european countries. the aim of this study was to assess the ability of mosquitoes to transfer dirofilaria immitis and dirofilaria repens in regions with temperate and subtropical climates. the possible impact of the symbiotic bacterium wolbachia on dirofilaria transmission was also investigated. 5333 female mosquitoes were collected at 11 points in central european russia and on the black sea coast during the period 2013-2017. out of ... | 2019 | 30644356 |
| lemongrass and cinnamon bark: plant essential oil blend as a spatial repellent for mosquitoes in a field setting. | plant essential oils (eos) have been considered as spatial repellents to help disrupt the pathogen transmission cycle of mosquitoes. our objective was to assess spatial repellency effects of eos on the tropical yellow fever mosquito, aedes aegypti (l.) (diptera: culicidae) and on local mosquito populations in coastal british columbia (canada). in laboratory experiments using protocols of the world health organization, three of the solitary eos tested proved repellent to ae. aegypti: cinnamon bar ... | 2019 | 31143941 |
| haemagogus leucocelaenus and haemagogus janthinomys are the primary vectors in the major yellow fever outbreak in brazil, 2016-2018. | the yellow fever virus (yfv) caused a severe outbreak in brazil in 2016-2018 that rapidly spread across the atlantic forest in its most populated region without viral circulation for almost 80 years. a comprehensive entomological survey combining analysis of distribution, abundance and yfv natural infection in mosquitoes captured before and during the outbreak was conducted in 44 municipalities of five brazilian states. in total, 17,662 mosquitoes of 89 species were collected. before evidence of ... | 2019 | 30866775 |
| bioefficacy of two nonpyrethroid insecticides for targeted indoor residual spraying against pyrethroid-resistant aedes aegypti. | we evaluated the efficacy of bendiocarb (ficam w® 80%) and pirimiphos-methyl (actellic 300cs® 28.16%), applied to different surfaces potentially sprayable within houses during the application of a targeted indoor residual spraying (tirs) against a field pyrethroid-resistant strain of aedes aegypti. bioassays with cones were performed on cement (walls), wood (doors), and textile (cloth) surfaces within typical houses in the mexican city of merida (n = 10). optimal residual efficacy (>80% of mean ... | 2019 | 31922939 |
| discriminating lethal concentrations for transfluthrin, a volatile pyrethroid compound for mosquito control in thailand. | pyrethroids are commonly used to control malaria and dengue vectors in thailand. the lack of specific lethal discriminating concentrations (dcs) for specific mosquito species has possibly compromised more accurate assessments of physiological susceptibility to various chemicals over time. previous studies have established dcs of various residual pyrethroids against specific mosquitoes in thailand. however, dcs for transfluthrin (tft), a highly volatile pyrethroid compound, against mosquito vecto ... | 2019 | 31922934 |
| aedes aegypti insecticide resistance underlies the success (and failure) of wolbachia population replacement. | mosquitoes that carry wolbachia endosymbionts may help control the spread of arboviral diseases, such as dengue, zika and chikungunya. wolbachia frequencies systematically increase only when the frequency-dependent advantage due to cytoplasmic incompatibility exceeds frequency-independent costs, which may be intrinsic to the wolbachia and/or can be associated with the genetic background into which wolbachia are introduced. costs depend on field conditions such as the environmental pesticide load ... | 2020 | 31919396 |
| sequencing of zikv genomes directly from ae. aegypti and cx. quinquefasciatus mosquitoes collected during the 2015-16 epidemics in recife. | zika virus (zikv) is a negative sense rna virus from the flaviviridae family, which was relatively unknown until the first human epidemic in micronesia, in 2007. since its spread to french polynesia and the americas. recife, the capital of pernambuco state and epicenter of the zika epidemic in brazil, experienced a large number of microcephaly cases and other congenital abnormalities associated to the zikv infection from, 2015 to 16. evidences suggest that both aedes aegypti and culex quinquefas ... | 2020 | 31918041 |
| development, larvicide activity, and toxicity in nontarget species of the croton linearis jacq essential oil nanoemulsion. | in this study, the essential oil (eo) from leaves of croton linearis jacq was extracted and characterized by gc/ms. the eo hydrophilic-lipophilic balance required (rhlb) for nanoemulsion (ne) development was determined by the griffin' method. for evaluating the larvicidal effect against aedes aegypti, the preparation process of ne was optimized, using a central composite design. it was also evaluated the possible toxic effect of ne in nontarget species. the leaves of c. linearis contain 1.50% of ... | 2020 | 31916152 |
| chemosensation: hate mosquitoes? peel beetroots! | finding the right lure for trapping pest insects is difficult. the typical smell of rain and humid soil, geosmin, now turns out to be a strong attractant for the yellow fever mosquito aedes aegypti. | 2020 | 31910367 |
| geographic shifts in the bioclimatic suitability for aedes aegypti under climate change scenarios in colombia. | the dengue, chikungunya and zika viruses are arboviruses predominantly transmitted to humans through the bite of the female mosquito aedes aegypti. currently, the vector represents a potential epidemiological risk in several latin american and pacific countries. however, little is known about the geographical distribution and bioclimatic suitability of this mosquito in the projected climate change scenarios in colombia. using a species distribution model of maximum entropy (maxent) based on pres ... | 2020 | 31909268 |
| surveillance for zika in mexico: naturally infected mosquitoes in urban and semi-urban areas. | zika cases have been reported in 29 out of the 32 states of mexico. information regarding which mosquito species might be driving zika virus transmission/maintenance in nature must be regularly updated. from january 2017 to november 2018, mosquitoes were collected indoors and outdoors using the cdc backpack aspirator in urban and semi-urban areas with evidence of mosquito-borne disease transmission. 3873 mosquito pools were tested for zika infection using the cdc trioplex real-time rt-pcr. for e ... | 2020 | 31902313 |
| mosquito iridescent virus: new records from nature and infections using strelkovimermis spiculatus (mermithidae) as a vector under laboratory conditions. | iridoviridae is a dna virus family that affects both vertebrates and invertebrates. immature aquatic stages of many dipteran species infected with iridovirus have been found in different places worldwide. the most represented genera of the culicidae family are aedes and psorophora. to date, sixteen species of aedes naturally infected with iridoviruses have been reported. moreover, there are four records for the genus psorophora, one for culiseta, and two for culex. in this paper, we report two n ... | 2020 | 31903519 |
| the olfactory basis of orchid pollination by mosquitoes. | mosquitoes are important vectors of disease and require sources of carbohydrates for reproduction and survival. unlike host-related behaviors of mosquitoes, comparatively less is understood about the mechanisms involved in nectar-feeding decisions, or how this sensory information is processed in the mosquito brain. here we show that aedes spp. mosquitoes, including aedes aegypti, are effective pollinators of the platanthera obtusata orchid, and demonstrate this mutualism is mediated by the orchi ... | 2020 | 31871198 |
| cytotoxic and larvicidal activities of stemona alkaloids from the aerial parts and roots of stemona curtisii hook.f. | a new stemona alkaloid glycoside derivative, 6-hydroxy-5,6-seco-stemocurtisinoside (4), was isolated from the ethanolic extract of the aerial parts of stemona curtisii hook.f., together with stemocurtisine (1), (11z)-1',2'-didehydrostemofoline (2) and 6-hydroxy-5,6-seco-stemocurtisine (3). whereas, stemocurtisine (1), stemocurtisinol (5) and oxyprotostemonine (6) were isolated from the roots. their structures were elucidated using 1d and 2d nmr spectroscopy as well as ms experiments. the extract ... | 2020 | 31899956 |
| distribution and frequency of the kdr mutation v410l in natural populations of aedes aegypti (l.) (diptera: culicidae) from eastern and southern mexico. | aedes aegypti (l.) is the primary vector of the viruses that cause dengue, zika, and chikungunya, for which effective vaccines and drugs are still lacking. current strategies for suppressing arbovirus outbreaks based on insecticide use pose a challenge because of the rapid increase in resistance. the widespread and excessive use of pyrethroid-based insecticides has created a large selection pressure for a kdr-type resistance, caused by mutations in the para gene of the voltage-gated sodium chann ... | 2020 | 31504686 |
| excito-repellency activity of andrographis paniculata (lamiales: acanthaceae) against colonized mosquitoes. | excito-repellency activity of plant extracts have been increasingly studied as mosquito repellents. in this study, the crude extract of andrographis paniculata was evaluated for its noncontact repellency, contact excitation (irritancy + repellency), and knockdown/toxicity response against five colonized mosquitoes; aedes aegypti (l.), aedes albopictus (skuse), anopheles dirus peyton & harrison, anopheles epiroticus linton & harbach, and culex quinquefasciatus say (diptera: culicidae) using an ex ... | 2020 | 31550361 |
| the global expansion of dengue: how aedes aegypti mosquitoes enabled the first pandemic arbovirus. | dengue is an emerging viral disease principally transmitted by the aedes (stegomyia) aegypti mosquito. it is one of the fastest-growing global infectious diseases, with 100-400 million new infections a year, and is now entrenched in a growing number of tropical megacities. behind this rapid rise is the simple adaptation of ae. aegypti to a new entomological niche carved out by human habitation. this review describes the expansion of dengue and explores how key changes in the ecology of ae. aegyp ... | 2020 | 31594415 |
| chikungunya virus: role of vectors in emergence from enzootic cycles. | chikungunya virus (chikv), a re-emerging mosquito-borne arbovirus, has caused millions of cases of severe, often chronic arthralgia during recent outbreaks. in africa, circulation in sylvatic, enzootic cycles involves several species of arboreal mosquito vectors that transmit among diverse nonhuman primates and possibly other amplifying hosts. most disease occurs when chikv emerges into a human-amplified cycle involving aedes aegypti and sometimes aedes albopictus transmission and extensive spre ... | 2020 | 31594410 |
| control of the 2018-2019 dengue fever outbreak in oman: a country previously without local transmission. | in december 2018, routine surveillance identified an autochthonous outbreak of dengue fever in muscat governorate, oman, a region previously free of dengue fever. | 2020 | 31639520 |
| phytochemical analysis of rhazya stricta extract and its use in fabrication of silver nanoparticles effective against mosquito vectors and microbial pathogens. | worldwide, billions of people are at risk from viruses, parasites and bacteria transmitted by mosquitoes, ticks, fleas and other vectors. over exploitation of chemical pesticides to overcome the mosquito borne diseases led to detrimental effects on environment and human health. the present research aims to explore bio-fabrication of metal silver nanomaterials using rhazya stricta extract against deadly mosquito vectors and microbial pathogens. the phytochemical profile of the r. stricta extracts ... | 2020 | 31655455 |
| insecticidal and mosquito repellent efficacy of the essential oils from stem bark and wood of hazomalania voyronii. | the use of hazomalania voyronii, popularly known as hazomalana, to repel mosquitoes and resist against insect attacks is handed down from generation to generation in madagascar. in the present study, we investigated the ability of the essential oils (eos) obtained from the stem wood, fresh and dry bark of h. voyronii to keep important mosquito vectors (aedes aegypti and culex quinquefasciatus) away, as well as their toxicity on three insect species of agricultural and public health importance (c ... | 2020 | 31654797 |
| molecular detection of dengue virus in mosquitoes as an early indicator to aid in the prevention of human infection in endemic areas. | human cases of dengue virus based on the national dengue control plan were compared with the molecular detection of the dengue virus in trapped mosquitoes, verifying the prediction and efficacy potentials of vector control between the two methodologies in a city with three endemic frontiers. molecular detection of dengue virus in trapped mosquitoes was significantly higher than in human cases (p = 0.0435). thus, molecular detection could be used as an early indicator to help prevent more human c ... | 2020 | 31697613 |
| the role of lulopat amino acid/proton symporters in midgut alkalinization in the sandfly lutzomyia longipalpis (diptera - psychodidae). | in lutzomyia longipalpis females, which are the main vectors of leishmania infantum in the americas, hematophagy is crucial for ovary development. the control of ph in the midgut during blood digestion is important to the functioning of the digestive enzymes, which release amino acids in the luminal compartment that are then transported through the enterocytes to the hemolymph for delivery to the ovary and other organs. in the present work, we investigated transport systems known as lulopats tha ... | 2020 | 31715141 |
| glycolytic profile shift and antioxidant triggering in symbiont-free and h2o2-resistant strigomonas culicis. | during their life cycle, trypanosomatids are exposed to stress conditions and adapt their energy and antioxidant metabolism to colonize their hosts. strigomonas culicis is a monoxenous protist found in invertebrates with an endosymbiotic bacterium that completes essential biosynthetic pathways for the trypanosomatid. our research group previously generated a wild-type h2o2-resistant (wtr) strain that showed improved mitochondrial metabolism and antioxidant defenses, which led to higher rates of ... | 2020 | 31760093 |
| larval exposure to bacteria modulates arbovirus infection and immune gene expression in adult aedes aegypti. | here we have investigated whether bacterial challenges to larval stages of aedes aegypti can influence the adults' immune and vector competence for dengue and zika viruses. we show that larval exposure to live bacillus thuringiensis berliner and enterobacter ludwigii can result in the modulation of virus infection at the adult stage in the absence of bacterial carry-over between the two developmental stages. we observed a significant reduction in virus infection intensity in the mosquitoes expos ... | 2020 | 31726064 |
| measuring the host-seeking ability of aedes aegypti destined for field release. | host seeking is an essential process in mosquito reproduction. field releases of modified mosquitoes for population replacement rely on successful host seeking by female mosquitoes, but host-seeking ability is rarely tested in a realistic context. we tested the host-seeking ability of female aedes aegypti mosquitoes using a semi-field system. females with different wolbachia infection types (wmel-, walbb-infected, and uninfected) or from different origins (laboratory and field) were released at ... | 2020 | 31769394 |
| discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (hkt) from aedes aegypti. | the mosquito aedes aegypti is the vector of arboviruses such as zika, chikungunya, dengue and yellow fever. these infectious diseases have a major impact on public health. the unavailability of effective vaccines or drugs to prevent or treat most of these diseases makes vector control the main form of prevention. one strategy to promote mosquito population control is the use of synthetic insecticides to inhibit key enzymes in the metabolic pathway of these insects, particularly during larval sta ... | 2020 | 31864777 |
| evolution of the innate and adaptive immune response in women with acute zika virus infection. | zika virus (zikv) is a flavivirus that is closely related to other human pathogens, such as dengue virus (denv)1. primary transmission usually involves aedes aegypti, which has expanded its distribution range considerably2, although rarer infection routes, including mother-to-fetus transmission, sexual contact and blood transfusion, have also been observed3-7. primary zikv infection is usually asymptomatic or mild in adults, with quickly resolved blood viraemia, but zikv might persist for months ... | 2020 | 31792427 |
| annona muricata: an alternate mosquito control agent with special reference to inhibition of detoxifying enzymes in aedes aegypti. | this study was aimed to investigate an effectual level of annona muricata (soursop) extracts on mosquito vectors namely, aedes aegypti, anopheles stephensi and culex quinquefasciatus. the toxicity study on non-target organism and other important biochemical marker enzymes to find and illustrate the exact mechanism of specific enzymes responsible for detoxifying allelochemicals. among the various soursop seed kernel extracts tested for larvicidal activity, the 0.9% saline extract exhibited maximu ... | 2020 | 31816498 |
| geosmin attracts aedes aegypti mosquitoes to oviposition sites. | geosmin is one of the most recognizable and common microbial smells on the planet. some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. in the vinegar fly drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. we have here investigated the effect of geosmin on the behavior of the yellow fever mosquito a ... | 2020 | 31839454 |
| reduced effectiveness of repellents in a pyrethroid-resistant strain of aedes aegypti (diptera: culicidae) and its correlation with olfactory sensitivity. | the mosquito, aedes aegypti (diptera: culicidae), is a vector of dengue fever, zika, chikungunya, and yellow fever viruses, and in many areas possesses significant levels of resistance to pyrethroids. behavioral performance was assessed in 15, 30, and 60 min exposures in a high throughput vapor phase spatial repellency assay to three contact repellent standards: n,n-diethyl-3-methylbenzamide (deet), ethyl 3-[acetyl(butyl)amino] propanoate (ir3535), and 2-undecanone, as well as pyrethrum extract, ... | 2020 | 31338960 |
| assessment of hymenoptera and non-hymenoptera insect bite and sting allergy among patients of tropical region of west bengal, india. | west bengal, india, is inhabited by abundance and variety of insects that triggers sensitization in some humans to inhalant allergens and/or insect stings/venoms. lack of research on this topic prevented accurate diagnosis and proper follow-up treatments to patients suffering from insect-induced allergies. the aim of our study was to identify the allergy-causing insects and evaluate resulting sensitization among a study population in west bengal, india. the skin prick test (spt) evaluated sensit ... | 2020 | 31228205 |
| mapping aedes aegypti (diptera: culicidae) and aedes albopictus vector mosquito distribution in brownsville, tx. | aedes mosquitoes are vectors of several emerging diseases and are spreading worldwide. we investigated the spatiotemporal dynamics of aedes aegypti (linnaeus) and aedes albopictus (skuse) mosquito trap captures in brownsville, tx, using high-resolution land cover, socioeconomic, and meteorological data. we modeled mosquito trap counts using a bayesian hierarchical mixed-effects model with spatially correlated residuals. the models indicated an inverse relationship between temperature and mosquit ... | 2020 | 31400202 |
| conservation of the voltage-sensitive sodium channel protein within the insecta. | the voltage-sensitive sodium channel (vssc) is essential for the generation and propagation of action potentials. vssc kinetics can be modified by producing different splice variants. the functionality of vssc depends on features such as the voltage sensors, the selectivity filter and the inactivation loop. mutations in vssc conferring resistance to pyrethroid insecticides are known as knockdown resistance (kdr). we analysed the conservation of vssc in both a broad scope and a narrow scope by th ... | 2020 | 31206812 |
| detection of fluorescent powders and their effect on survival and recapture of aedes aegypti (diptera: culicidae). | the use of insect markers, such as fluorescent powders, is a useful tool for studying ecological and epidemiological questions. evaluating their effect on vectors of human disease agents, such as the invasive mosquito vector aedes aegypti (linnaeus), is crucial for their practical and reliable use, especially in parameters linked to the risk of disease transmission such as adult survival, dispersal, and host-seeking. seven fluorescent powders (hercules radiant, dayglo (dg), risk reactor (rr), an ... | 2020 | 31587060 |
| function of aedes aegypti galectin-6 in modulation of cry11aa toxicity. | galectins are a family of β-galactoside binding proteins, and insect galectins play a role in immune responses and may also affect cry toxin activity. in this study, we aimed to further understand the function and molecular mechanism of aedes aegypti galectin-6 in modulation of cry11aa toxicity. a. aegypti galectin-6 was cloned, and the recombinant galectin-6 was expressed and purified. bioassays indicated that galectin-6 could reduce the toxicity of cry11aa, protecting a. aegypti larvae. to det ... | 2020 | 31836060 |
| towards the optimization of botanical insecticides research: aedes aegypti larvicidal natural products in french guiana. | natural products have proven to be an immeasurable source of bioactive compounds. the exceptional biodiversity encountered in amazonia, alongside a rich entomofauna and frequent interactions with various herbivores is the crucible of a promising chemodiversity. this prompted us to search for novel botanical insecticides in french guiana. as this french overseas department faces severe issues linked to insects, notably the strong incidence of vector-borne infectious diseases, we decided to focus ... | 2020 | 31539525 |
| adaptation to temperate climates: evidence of photoperiod-induced embryonic dormancy in aedes aegypti in south america. | dormancy is a developmental arrest in arthropods, in response to unfavorable conditions in temporally varying environments. in aedes aegypti, the supposed inability of eggs to inhibit hatching has been used to explain the restriction of this species to tropical and subtropical regions. however, the geographic range of ae. aegypti is constantly expanding towards temperate regions. thus, the aim of the present study was to assess the ability of ae. aegypti individuals from a temperate region (buen ... | 2020 | 31125550 |