Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| an evaluation of strontium chloride, rappaport and strontium selenite enrichment for the isolation of salmonellas from man, animals, meat products and abattoir effluents. | strontium chloride enrichment broth was found to be comparable to rappaport broth for the recovery of a wide range of salmonella serotypes from man, animals, meat products and effluents. with the exception of cloacal samples from reptiles, both procedures were superior to selenite f.the performance of strontium chloride mand selenite f enrichment was improved when effluent samples were incubated at 43 degrees c.strontium chloride m and rappaport enrichment were superior to selenite f for the iso ... | 1972 | 4503874 |
| regulation of the methionine feedback-sensitive enzyme in mutants of salmonella typhimurium. | assay of the first enzyme unique to methionine biosynthesis, homoserine-o-transsuccinylase, in metj and metk regulatory mutants of salmonella typhimurium showed that synthesis of the enzyme was derepressed seven- and fourfold, respectively. the possibility of noncoordinate regulation of the methionine enzymes is discussed. in meta feedback-resistant mutants, the enzyme activity can be inhibited in vitro by 10 mms-adenosylmethionine but not by 10 mm l-methionine; hence, the synergistic inhibition ... | 1972 | 4550678 |
| inducer exclusion and repression of enzyme synthesis in mutants of salmonella typhimurium defective in enzyme i of the phosphoenolpyruvate: sugar phosphotransferase system. | 1972 | 4550766 | |
| leucyl-transfer ribonucleic acid synthetase from a wild-type and temperature-sensitive mutant of salmonella typhimurium. | leucyl-transfer ribonucleic acid (trna) synthetase was purified 100-fold from extracts of salmonella typhimurium. the partially purified enzyme had the following k(m) values: leucine, 1.1 x 10(-5)m; adenosine triphosphate, 6.5 x 10(-4)m; trna(i) (leu), 4.1 x 10(-8)m; trna(ii) (leu), 4.3 x 10(-8)m; trna(iii) (leu), 5.3 x 10(-8)m; and trna(iv) (leu), 2.9 x 10(-8)m. the trna(leu) fractions were isolated from salmonella bulk trna by chromatography on reversed-phase columns and benzoylated diethylami ... | 1972 | 4550813 |
| derivation of an f-merogenote and a phi-80 high-frequency transducing phage carrying the histidine operon os salmonella. | an f' factor, fs400, carrying the his operon, the gnd gene, and the rfb gene cluster of salmonella typhimurium was isolated. fs400 was introduced into an escherichia coli strain having a lengthy deletion of the his gene region. from this strain, hfr derivatives were isolated which had the f' factor integrated in the tonb locus near the attachment site of phi80. one of the hfr strains was lysogenized with a heat-inducible, h mutant of phi80, and from this strain a high-frequency transducing phage ... | 1972 | 4550819 |
| relationship of population kinetics of salmonella typhimurium and cultural methodology. | 1972 | 4550839 | |
| host morphology and phage dna synthesis following exposure of salmonella typhimurium (p22 mnt ts 1) to high temperature. | 1972 | 4550899 | |
| growth of salmonella typhimurium in skim milk concentrates. | the influence of various levels of skim milk solids and temperature on the duration of lag phase, growth rate, and extent of growth of salmonella typhimurium was investigated. the effect on growth of salmonellae (and a strain of escherichia coli) of reduced pressure at a constant solids level and under conditions simulating vacuum condensation of skim milk was also studied. s. typhimurium grew when inoculated into skim milk solutions ranging from 10 to 60% solids and over a temperature range of ... | 1972 | 4551045 |
| comparison of oral vaccination or furazolidone prophylaxis for salmonella typhimurium infection in chicks. | 1972 | 4551155 | |
| epoxides of carcinogenic polycyclic hydrocarbons are frameshift mutagens. | k-region epoxides of the carcinogens benz[a] anthracene, dibenz[a,h]anthracene, and 7-methylbenz[a] anthracene are mutagenic in strains of salmonella typhimurium designed to detect frameshift mutagens. parent hydrocarbons, k-region diols and phenols and some other epoxides are inactive as mutagens in these tests. polycyclic hydrocarbon epoxides, and other presumed proximal carcinogens, are discussed as examples of intercalating agents with reactive side chains. it has been shown previously that ... | 1972 | 4551487 |
| histidine regulation in salmonella typhimurium. ix. histidine transfer ribonucleic acid of the regulatory mutants. | 1972 | 4551510 | |
| -isopropylmalate synthase from salmonella typhimurium. analysis of the guaternary structure and its relation to function. | 1972 | 4551511 | |
| effect of ph on the pathogenic functions of salmonella typhimurium. | 1972 | 4551617 | |
| isolation and partial characterization of regulatory mutants of the pyrimidine pathway in salmonella typhimurium. | mutants of salmonella typhimurium affected in the regulation of pyrimidine biosynthesis were isolated by two methods. the first involved screening for bacteria able to feed a pyrimidine-requiring indicator strain, and the second involved selection for bacteria simultaneously resistant to two pyrimidine analogues, 5-fluorouracil and 5-fluorouridine, in a s. typhimurium strain unable to degrade 5-fluorouridine. among the mutants isolated by these methods are constitutive mutants, producing high le ... | 1972 | 4551742 |
| the pi-histidine factor of salmonella typhimurium: a demonstration that pi-histidine factor integrates into the chromosome. | the salmonella typhimurium pi-histidine episome was identified by ames et al. (2) in an unstable partial revertant of a deletion mutation-containing strain, hisg203. hisg203 lacks the histidine operator, promoter, and part of the first structural gene. in this paper, we study some properties of pi factor and demonstrate a low frequency of pi integration into the chromosome at or near the histidine region. | 1972 | 4551760 |
| a new transducing phage related to p22 of salmonella typhimurium. | 1972 | 4551762 | |
| salmonella in pigs and animal feeding stuffs in england and wales and in denmark. | a comparison has been made between the incidence of salmonellas in pigs and feeding stuffs in england and wales and in denmark. in denmark there is veterinary legislation requiring the sterilization of imported and home produced feed ingredients of animal origin. there is no such legislation in england and wales. in denmark 0.3% of resterilized imported meat and bone meal was contaminated with salmonellas. this compared with 23% of meat and bone meal in england and wales and 20-27% of other ingr ... | 1972 | 4552257 |
| physiological and genetical studies on a mutant of salmonella typhimurium which is temperature-sensitive for dna synthesis. | 1972 | 4552497 | |
| observations on starvation-induced resistance enhancement (sire) in salmonella typhimurium. | 1972 | 4552602 | |
| a pigeon host-adapted type of salmonella typhimurium var. copenhagen. | 1972 | 4552673 | |
| effect of an r factor on resistance of salmonella typhimurium to radiation and chemical treatment. | 1972 | 4552776 | |
| heat resistance of salmonellae in concentrated milk. | the heat resistance of escherichia coli, salmonella typhimurium, and salmonella alachua in milk solutions containing 10, 30, 42, and 51% (w/w) skim milk for total solids was determined. increased milk-solids level effected a significant increase in the heat resistance of each organism. although e. coli was more heat-resistant than both strains of salmonella in 10% milk, the situation was reversed in 42 and 51% milk. prior growth temperature was found to exert a profound effect on the heat resist ... | 1972 | 4552893 |
| influence of temperature on the biosynthesis of iron transport compounds by salmonella typhimurium. | the biosynthesis of phenolate iron transport compounds by salmonella typhimurium tm-1 is temperature-sensitive. as the temperature of incubation is raised from 31.0 to 36.9 c, the organism excretes less iron transport compound into the medium. the organism in unable to grow at 40.3 c on a 1% succinatesalts medium unless supplemented with such iron transport compounds. the iron requirement for maximum cell yields on this medium is 0.10 mug/ml. the biosynthesis of phenolate iron transport compound ... | 1972 | 4552991 |
| comparative chemistry of 30s ribosomal proteins of salmonella typhimurium. | individual proteins from the 30s ribosome of salmonella typhimurium were isolated and compared with their counterparts in escherichia coli. amino acid composition data reveal either no significant differences, or only minor differences in a few residues between paired proteins. tryptic peptide fingerprints were used to amplify any possible differences between protein pairs. | 1972 | 4552994 |
| structural genes for ornithine transcarbamylase in salmonella typhimurium and escherichia coli k-12. | mutations of salmonella typhimurium affecting the structural gene for ornithine transcarbamylase (argl) have been isolated and mapped. the two ornithine transcarbamylase loci in escherichia coli k-12 have been demonstrated by f' episome transfer. | 1972 | 4553006 |
| [virulence and immunogenicity of salmonella typhimurium rough mutants]. | 1972 | 4553290 | |
| inhibition by rabbit antibacterial igg of the bactericidal effect on salmonella typhimurium 395 mro by normal cattle serum. | 1972 | 4553302 | |
| histidine regulation in salmonella typhimurium. x. kinetic studies of mutant histidyl transfer ribonucleic acid synthetases. | 1972 | 4553439 | |
| isolation and phenotypes of mutants from salmonella typhimurium defective in formate hydrogenlyase activity. | a new method is described for the isolation of different mutants defective in formic dehydrogenase activity measured with benzyl viologen as electron acceptor. | 1972 | 4553845 |
| immunologic memory cells of bone marrow origin. increased burst size of specific immunocyte precursors. | individual immunocompetent precursor cells of (c57bl/10 x c3h)f(1) mouse marrow generate, on transplantation, three to five times more antibody-forming cells localized in recipient spleens during secondary than during primary immune responses. the increased burst size is immunologically specific since antigens of horse and chicken erythrocytes and of salmonella typhimurium do not cause this effect in marrow cells responsive to sheep red blood cells. both sensitized and nonsensitized precursors r ... | 1972 | 4553850 |
| epidemiologic investigation of an outbreak of fatal enteritis and abortion associated with dietary change and salmonella typhimurium infection in a dairy herd. a case report. | 1972 | 4554167 | |
| acquired resistance to and comparative virulence of salmonella typhimurium demonstrated by cutaneous lesions in guinea pigs. | 1972 | 4554295 | |
| new deoxyribonuclease activity after bacteriophage p22 infection. | extracts from p22-infected and uninfected cultures of salmonella typhimurium were subjected to deoxyribonucleic acid (dna)-cellulose and diethylaminoethyl-cellulose chromatography. comparison of the elution patterns revealed that in infected cells there is a decrease in the amount of nuclease activity specific for denatured dna and an increase in the amount of nuclease activity specific for native dna. the latter activity was shown to differ from a similar host enzyme in mg(2+), mn(2+), and ph o ... | 1972 | 4554463 |
| inhibitory effect of bacteriophage p22 infection on host cell deoxyribonuclease activity. | infection of salmonella typhimurium with phage p22 causes a decrease in the activity of host deoxyribonuclease which degrades single-stranded deoxyribonucleic acid (dna). this decrease is reversed when the infecting phage is p22c(+); it is not reversed if the infecting phage kills the cell. the decrease does not occur in infections with p22ts25.1 (which only adsorbs and injects dna) or in infections of a lysogen by a nonvirulent phage. it does occur, however, after infections with other phages w ... | 1972 | 4554464 |
| alteration of the rate of cell division independent of the rate of dna synthesis in a mutant of salmonella typhimurium. | 1972 | 4554473 | |
| characterization of a recessive-lethal amber suppressor strain of salmonella typhimurium by in vitro synthesis of t 4 lysozyme. | 1972 | 4554648 | |
| viability of staphylococcus aureus, salmonella typhimurium and salmonella senftenberg heated and recovered on a solid medium of controlled water activity. | 1972 | 4555285 | |
| partial reversions of a proline auxotroph of salmonella typhimurium. cross-feeding associated with cell-to-cell contact. | 1972 | 4555298 | |
| the mutagenicity of benzimidazole and benzimidazole derivatives. i. forward and reverse mutations in salmonella typhimurium caused by benzimidazole and some of its derivatives. | 1972 | 4555299 | |
| mutagenicity of n-nitrosopiperazines for salmonella typhimurium in the host-mediated assay. | 1972 | 4555385 | |
| location on the chromosome of salmonella typhimurium of genes governing pyrimidine metabolism. ii. uridine kinase, cytosine deaminase and thymidine kinase. | 1972 | 4555675 | |
| comparative efficacy of whole and disintegrated killed vaccines against salmonella typhimurium in mice. | 1972 | 4555727 | |
| mechanism of assembly of the outer membrane of salmonella typhimurium. isolation and characterization of cytoplasmic and outer membrane. | 1972 | 4555955 | |
| methionine regulatory defects in salmonella typhimurium arising from amber-suppressible mutations. | 1972 | 4556253 | |
| non-smooth mutants of salmonella typhimurium: differentiation by phage sensitivity and genetic mapping. | 1972 | 4556257 | |
| purification and properties of a component of histidine transport in salmonella typhimurium. the histidine-binding protein j. | 1972 | 4556308 | |
| studies on the survival of salmonella typhimurium and salmonella bovis-morbificans on soil and sheep faeces. | 1972 | 4556470 | |
| inhibition of salmonella typhimurium by fowl caecal cultures. | 1972 | 4556471 | |
| a histidine operator-constitutive mutation decreases the frequency of recombination within the histidine operon of salmonella typhimurium. | 1972 | 4556783 | |
| precipitation of lipopolysaccharides from rough mutants of salmonella typhimurium by an a-hemagglutinin from helix pomatia. | 1972 | 4557086 | |
| expression of the escherichia coli k, b and phage p1 dna host specificities in salmonella typhimurium. | 1972 | 4557386 | |
| [infection of a newborn infant by breast milk containing salmonella typhimurium]. | 1972 | 4557553 | |
| two forms of biosynthetic acetohydroxy acid synthetase in salmonella typhimurium. | 1972 | 4557731 | |
| defective cell division in thermosensitive mutants of salmonella typhimurium. | 1972 | 4558189 | |
| imparired dna synthesis and envelope defect in a mutant of salmonella typhimurium. | 1972 | 4558190 | |
| replication of extrachromosomal elements in a dna synthesis initiation mutant of salmonella typhimurium. | 1972 | 4558609 | |
| replication and lysogeny with phage p22 in salmonella typhimurium. | 1972 | 4559086 | |
| partial characterization of phosphoribosyl transferase, phosphoribosyl anthranilate isomerase, and indole glycerol phosphate synthase from serratia marcescens. | the molecular organization of the enzymes phosphoribosyl (pr) transferase, phosphoribosyl anthranilate (pra) isomerase, and indole glycerol phosphate (ingp) synthase of the tryptophan biosynthetic pathway of serratia marcescens was investigated and compared with that reported in other enteric bacteria. pra isomerase and ingp synthase activities were found to reside in a single polypeptide chain, a situation analogous to that in escherichia coli, salmonella typhimurium, and aerobacter aerogenes. ... | 1972 | 4559725 |
| mannitol sensitivity. | the addition of mannitol to cultures of salmonella typhimurium mutants missing mannitol-1-phosphate dehydrogenase causes stasis or lysis. mannitol-1-phosphate accumulates intracellularly to concentrations of 20 mm. the incorporation of acetate into lipid is inhibited before cell wall, protein, or nucleic acid synthesis. | 1972 | 4559727 |
| location of trpr mutations in the serb-thr region of salmonella typhimurium. | tryptophan biosynthesis in salmonella is controlled by at least one regulatory gene, trpr, which is cotransducible with thr genes and not with the trp operon. mutations in trpr cause derepression of tryptophan enzyme synthesis and confer resistance to growth inhibition by 5-methyltryptophan. nineteen trpr mutations were mapped with respect to thra and serb markers by two-point (ratio) and three-point transduction tests. the results are all consistent with the site order serb80-trpr-thra59 on the ... | 1972 | 4559729 |
| mutants of salmonella typhimurium that are insensitive to catabolite repression of proline degradation. | in salmonella typhimurium the two enzymes of proline catabolism, proline oxidase and delta(1)-pyrroline-5-carboxylic acid dehydrogenase, are subject to catabolite repression when the cells are grown in the presence of glucose. mutants partially relieved of catabolite repression (putr) for the proline catabolic enzymes have been isolated by selection on agar plates containing glucose and proline. the specificity of the catabolite repression-insensitive character for the enzymes of proline utiliza ... | 1972 | 4559730 |
| effect of cyclopentaneglycine on metabolism in salmonella typhimurium. | cyclopentaneglycine (cpg) inhibited the growth of wild-type salmonella typhimurium. the inhibition was overcome by isoleucine or any isoleucine precursor formed after threonine. cpg appeared to mimic isoleucine as a strong inhibitor of the activity of l-threonine deaminase. the analogue was a poor inhibitor of isoleucyl-transfer ribonucleic acid synthetase. cpg did not appear to be incorporated into protein nor did it replace isoleucine in repression. cells that had recovered from growth inhibit ... | 1972 | 4559733 |
| regulation of homocysteine biosynthesis in salmonella typhimurium. | the regulation of the homocysteine branch of the methionine biosynthetic pathway in salmonella typhimurium has been reexamined with the aid of a new assay for the first enzyme. the activity of this enzyme is subject to synergistic feedback inhibition by methionine plus s-adenosylmethionine. the synthesis of all three enzymes of the pathway is regulated by noncoordinate repression. the enzymes are derepressed in metj and metk regulatory mutants, suggesting the existence of regulatory elements com ... | 1972 | 4559736 |
| iron uptake in salmonella typhimurium: utilization of exogenous siderochromes as iron carriers. | aerobic microorganisms have evolved a variety of siderochromes, special ligands which can dissolve insoluble ferric iron and facilitate its transport into the cell. we have found that enb mutants of salmonella typhimurium blocked in the biosynthesis of enterobactin (its natural iron carrier) are able to utilize siderochromes of different types made by other microorganisms as iron carriers. the antibiotic albomycin delta(2) was used to select mutants defective in ferrichrome-mediated iron uptake. ... | 1972 | 4559824 |
| regulation of histidyl-transfer ribonucleic acid synthetase formation in a histidyl-transfer ribonucleic acid synthetase mutant of salmonella typhimurium. | control of formation of the histidyl-transfer ribonucleic acid (trna) synthetase with an increased k(m) for histidine was studied in a hiss mutant of salmonella typhimurium. histidine restriction of both the hiss and hiss(+) strains resulted in a derepression of synthesis of histidyl-trna synthetase. when grown in a concentration less than the k(m) (100 mug/ml) of l-histidine, the hiss mutant maintained a higher level of histidyl-trna synthetase than the hiss(+) strain. addition of excess amount ... | 1972 | 4559825 |
| genetic transfer of salmonella typhimurium and escherichia coli lipopolysaccharide antigens to escherichia coli k-12. | escherichia coli k-12 varkappa971 was crossed with a smooth salmonella typhimurium donor, hfrk6, which transfers early the ilv-linked rfa region determining lipopolysaccharide (lps) core structure. two ilv(+) hybrids differing in their response to the lps-specific phages fo and c21 were then crossed with s. typhimurium hfrk9, which transfers early the rfb gene cluster determining o repeat unit structure. most recombinants selected for his(+) (near rfb) were agglutinated by salmonella factor 4 an ... | 1972 | 4559827 |
| salmonella typhimurium-escherichia coli hybrids for the tryptophan region. | fifty-eight hybrids were analyzed for their phenotypic stability, presence and nature of cryptic trp alleles and by p22-mediated transduction to yield percent homologies. the hybrids fall into 5 distinguishable classes: a haploid class in which selected e. coli genes replace equivalent sites in the s. typhimurium chromosome; three merodiploid classes in which the selected e. coli genes are integrated at novel sites in the s. typhimurium chromosome-on the same transducing fragment as the female g ... | 1972 | 4560066 |
| a study of salmonella typhimurium infection at a swine-testing station. | 1972 | 4560316 | |
| transduction of salmonella typhimurium genetic material by coliphage p1 in s. typhimurium hfr x escherichia coli hybrids. | 1972 | 4560489 | |
| the primary structure of the phase-1 flagellar protein of salmonella typhimurium. i. the tryptic peptides. | 1972 | 4560500 | |
| regulatory mutants of the deo regulon in salmonella typhimurium. | 1972 | 4560588 | |
| the specific secondary biological activities of rabbit igm and igg anti-salmonella typhimurium 'o' antibodies isolated during the development of the immune response. | 1972 | 4560740 | |
| distinction between far- and near-ultraviolet light killing of recombinationless (reca) salmonella typhimurium. | 1972 | 4560818 | |
| lipid biosynthesis during the recovery of salmonella typhimurium from thermal injury. | 1972 | 4560912 | |
| transient depression in the active transport across the membrane of salmonella typhimurium, after infection with bacteriophage p22. | 1972 | 4561234 | |
| temperature sensitive initiation of dna synthesis in a mutant of salmonella typhimurium. | 1972 | 4561423 | |
| cooh-terminal amino acid sequence of histidinol dehydrogenase from a salmonella typhimurium mutant. | 1972 | 4561942 | |
| a ribose binding protein of salmonella typhimurium. | 1972 | 4562155 | |
| sex-determined chemotaxis in salmonella typhimurium lt2. | 1972 | 4562213 | |
| the effect of triazole on cysteine biosynthesis in salmonella typhimurium. | 1972 | 4562307 | |
| deletion mapping of the genes coding for hpr and enzyme i of the phosphoenolpyruvate: sugar phosphotransferase system in salmonella typhimurium. | sugars transported by a bacterial phosphoenolpyruvate:sugar phosphotransferase system (pts) require two soluble proteins: hpr, a low-molecular-weight phosphate-carrier protein, and enzyme i. the structural genes coding for hpr (ptsh) and enzyme i (ptsi) are shown to be cotransducible in salmonella typhimurium. the gene order of this region of the salmonella chromosome is cysa-trza-ptsh-ptsi...(crr). a method for the isolation of trza-pts deletion is described. one class of pts deletions extends ... | 1972 | 4562394 |
| isoleucine auxotrophy due to feedback hypersensitivity of biosynthetic threonine deaminase. | isoleucine-deficient mutants of salmonella typhimurium were isolated. three groups of mutants can be discerned by their nutritional requirements and enzyme patterns. (i) mutants which grow with isoleucine alone are devoid of biosynthetic threonine deaminase (td). (ii) mutants growing with isoleucine and valine are devoid of transaminase b. (iii) mutants growing with either isoleucine or threonine have normal levels of td. however, the sensitivity of this enzyme to feedback inhibition by isoleuci ... | 1972 | 4562397 |
| transfer among erwinia spp. and other enterobacteria of antibiotic resistance carried on r factors. | antibiotic resistance carried on r factors was transferred by conjugation from escherichia coli b/r and shigella flexneri 1a to erwinia spp. tetracycline resistance (tetr) carried on r factor r100 drd-56 was transferred from e. coli b/r to strains of erwinia amylovora, e. aroideae, e. atroseptica, e. chrysanthemi, e. cytolytica, e. dissolvens, e. herbicola, e. nigrifluens, and e. nimipressuralis, but not to strains of erwinia carotovora, e. carnegieana, e. dieffenbachiae, e. oleraceae, and e. qu ... | 1972 | 4562410 |
| p22-mediated transduction analysis of the rough a (rfa) region of the chromosome of salmonella typhimurium. | seven temperature-sensitive rough mutants of salmonella typhimurium were found to be sensitive to smooth-specific phages at low temperature (25 c, 30 c) and resistant or partially resistant to rough-specific phages, whereas at high temperatures (37 c, 45 c) they were resistant or partially resistant to smooth-specific phages but sensitive to rough-specific phages. these data indicate that at low temperature each strain makes lipopolysaccharide which is relatively normal, but at high temperatures ... | 1972 | 4562411 |
| insertion of the f factor into the cluster of rfa (rough a) genes of salmonella typhimurium. | from f(+) strains of salmonella typhimurium, isolates were obtained representing two new classes of hfr strains, hfrk1 and hfrk2, in which the insertion of the f factor into the rfa genes results in chromosome mobilization either clockwise or anticlockwise from rfa, and in the rfa phenotype. the point of insertion of the f factor into the cluster of rfa genes, revealed by studies of the early transfer of their normal alleles, is as follows: xyl-cyse-rfa-657 (hfrk2-1, sa540 -->)-(<-- hfrk1-1, sa4 ... | 1972 | 4562416 |
| toxicity of l-tryptophan photoproduct on recombinationless (rec) mutants of salmonella typhimurium. | l-tryptophan after exposure to black light becomes toxic for recombinationless (rec) mutants of salmonella typhimurium. fifty-six radiation-sensitive mutants were screened for sensitivity to the tryptophan photoproduct; the rec and exr (x-ray sensitive) mutants are sensitive, whereas the uvr, hcr, and wild-type strains are resistant. a number of catabolic products of tryptophan and compounds related to tryptophan were screened for toxicity to rec strain; these are nontoxic or far less toxic for ... | 1972 | 4562417 |
| transmission of salmonella typhimurium in battery-reared chicks. | 1972 | 4562576 | |
| an intercistronic region in the histidine operon of salmonella typhimurium. | 1972 | 4562711 | |
| cell division and the production of cells lacking nuclear bodies in a mutant of salmonella typhimurium. | 1972 | 4562868 | |
| [salmonella typhimurium as a cause of acute osteitis in an infant 7 weeks old]. | 1972 | 4563694 | |
| purine phosphoribosyltransferases of salmonella typhimurium. | evidence is presented that salmonella typhimurium contains two guanine phosphoribosyltransferases. | 1972 | 4563965 |
| temperature-dependent utilization of meso-inositol: a useful biotyping marker in the genealogy of salmonella typhimurium. | salmonella typhimurium strains from natural sources either ferment or do not ferment meso-inositol in peptone water in 24 hr at 37 c. ninety-five percent of the strains that are designated inositol-nonfermenting on the basis of their phenotype at 37 c ferment inositol when incubated at 25 c. two classes of temperature-sensitive mutants were detected among the 712 strains of s. typhimurium examined. the occurrence of low-temperature fermentation of inositol among wild-type strains of s. typhimuri ... | 1972 | 4563975 |
| restoration of phosphoribosyl transferase activity by partially deleting the trpb gene in the tryptophan operon of salmonella typhimurium. | the amber mutant trpa28, which contains a mutation mapping within the so-called "unusual" region of the tryptophan (trp) operon of salmonella typhimurium (between the genes trpa and trpb), lacks both components of the anthranilate synthetase (as)-phosphoribosyl transferase (prt) enzyme complex, the products of the genes trpa and trpb, respectively. twenty-six revertants of this mutant selected on minimal medium supplemented with anthranilic acid, a substrate of prt, contain deletions of various ... | 1972 | 4563982 |
| genetic separation of hypoxanthine and guanine-xanthine phosphoribosyltransferase activities by deletion mutations in salmonella typhimurium. | certain proab deletion mutants of salmonella typhimurium were found to be simultaneously deleted in a gene required for the utilization of guanine and xanthine (designated gxu). these mutants were resistant to 8-azaguanine and when carrying an additional pur mutation were unable to use guanine or xanthine as a purine source. the defect was correlated with deficiencies in the uptake and phosphoribosyltransferase activities for guanine and xanthine. hypoxanthine and adenine activities were unalter ... | 1972 | 4563984 |
| radiometric detection of some food-borne bacteria. | studies on detection of bacteria by radiometric techniques have been concerned primarily with aerobic species in clinical specimens. the data presented here are related to detection of aerobic and anaerobic species that are of significance in foods, by measurement of (14)co(2) evolved from the metabolism of (14)c-glucose. salmonella typhimurium and staphylococcus aureus were inoculated into tryptic soy broth containing 0.0139 muci of (14)c glucose/ml of medium. detection times ranged from 10 to ... | 1972 | 4564040 |
| oral immunization of mice with killed salmonella typhimurium vaccine. | a study was undertaken to assess the efficacy of oral, parenteral, and intraperitoneal immunization methods of administering killed salmonella typhimurium vaccine to mice and to evaluate the effectiveness of single and multiple doses of the vaccine containing varied numbers of the killed bacteria. a further objective of this study was to evaluate the effect of adding substances to the vaccine to which have been ascribed "adjuvant" properties. the protection was estimated by isolation of bacteria ... | 1972 | 4564152 |
| formation of hybrids between coliphage lambda and salmonella phage p22 with a salmonella typhimurium hybrid sensitive to these phages. | an unusual salmonella typhimurium hybrid with sensitivity to coliphage lambda and salmonella phage p22 has been recovered from matings between an escherichia coli k-12 hfr donor and an s. typhimurium recipient. the hybrid is an excellent host for achieving genetic recombination between lambda and p22. two broad classes of hybrid phages were isolated. the lambda-p22 hybrid class, which has the protein coat of lambda, contains at least the c region of p22. the p22-lambda hybrid class has the prote ... | 1972 | 4564201 |
| carcinogens as frameshift mutagens: metabolites and derivatives of 2-acetylaminofluorene and other aromatic amine carcinogens. | several carcinogenic metabolites of the carcinogen 2-acetyl-aminofluorene, especially 2-nitrosofluorene and n-hydroxy-2-aminofluorene, are potent frameshift mutagens for salmonella typhimurium. 2-nitrosonaphthalene, 2-nitrosophenanthrene, 4-nitroso-trans-stilbene, 4-nitrosobiphenyl, and 4-nitrosoazobenzene, all of which are metabolites or likely metabolites of carcinogenic aromatic amines, are also potent frameshift mutagens. these compounds may be frameshift mutagens of the class that intercala ... | 1972 | 4564203 |
| model approach to immunological rejuvenation of the aged. | reconstitution of a damaged or exhausted immune system by injection of genetically compatible immunocompetent cells (immunologic rejuvenation) is a promising approach for restoration of immune activity. by using this model, spleen cells from young-adult mice, previously immunized with salmonella typhimurium, were transferred to either young-adult or old, syngeneic recipients before or after storage at -196 c. the susceptibility of recipient mice was then determined by challenging them at increas ... | 1972 | 4564285 |
| ribosomal vaccines. i. immunogenicity of ribosomal fractions isolated from salmonella typhimurium and yersinia pestis. | the immunogenicity of ribosomes and ribosomal subfractions isolated from yersina pestis and salmonella typhimurium has been studied. ribosomes and ribosomal protein isolated from s. typhimurium protected mice against lethal challenge. ribosomal ribonucleic acid isolated by phenol extraction failed to induce any significant level of protection in mice. none of the ribosomes or ribosomal subfractions isolated from y. pestis were effective in inducing immunity to lethal challenge. these results sug ... | 1972 | 4564407 |