Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| natural killer cell functions during the innate immune response to pathogenic streptococci. | dendritic cells (dcs) and nk cells play a crucial role in the first phase of host defense against infections. group b streptococcus (gbs) and streptococcus suis are encapsulated streptococci causing severe systemic inflammation, leading to septicemia and meningitis. yet, the involvement of nk cells in the innate immune response to encapsulated bacterial infection is poorly characterized. here, it was observed that these two streptococcal species rapidly induce the release of ifn-γ and that nk ce ... | 2017 | 28706510 |
| serotype-specific role of antigen i/ii in the initial steps of the pathogenesis of the infection caused by streptococcus suis. | streptococcus suis is one of the most important post-weaning porcine bacterial pathogens worldwide. the serotypes 2 and 9 are often considered the most virulent and prevalent serotypes involved in swine infections, especially in europe. however, knowledge of the bacterial factors involved in the first steps of the pathogenesis of the infection remains scarce. in several pathogenic streptococci, expression of multimodal adhesion proteins known as antigen i/ii (agi/ii) have been linked with persis ... | 2017 | 28705175 |
| erratum to: genome-wide analysis of an avirulent strain that induces protective immunity against challenge with virulent streptococcus suis serotype 2. | 2017 | 28676041 | |
| rutin inhibits streptococcus suis biofilm formation by affecting cps biosynthesis. | streptococcus suis (s. suis) form biofilms and causes severe diseases in humans and pigs. biofilms are communities of microbes embedded in a matrix of extracellular polymeric substances. eradicating biofilms with the use of antibiotics or biocides is often ineffective and needs replacement with other potential agents. compared to conventional agents, promising and potential alternatives are biofilm-inhibiting compounds without impairing growth. here, we screened a s. suis adhesion inhibitor, rut ... | 2017 | 28670278 |
| a single amino acid polymorphism in the glycosyltransferase cpsk defines four streptococcus suis serotypes. | the capsular polysaccharide (cps) is the major virulence factor of the emerging zoonotic pathogen streptococcus suis. cps differences are also the basis for serological differentiation of the species into 29 serotypes. serotypes 2 and 1/2, which possess identical gene content in their cps loci, express cpss that differ only by substitution of galactose (gal) by n-acetylgalactosamine (galnac) in the cps side chain. the same sugar substitution differentiates the cps of serotypes 14 and 1, whose cp ... | 2017 | 28642597 |
| the manganese efflux system mnte contributes to the virulence of streptococcus suis serotype 2. | manganese is an essential micronutrient to bacteria and plays an important role in bacterial physiology. however, an excess of manganese is extremely deleterious to the cell. the manganese efflux system is used to control intracellular manganese levels by some bacteria. in this study, we have identified a cation efflux family protein (mnte) that functions as a manganese export system in streptococcus suis serotype 2. to investigate the role of mnte in s. suis 2, a mnte deletion mutant (δmnte) an ... | 2017 | 28629722 |
| the streptococcus suis factor h-binding protein: a key to unlocking the blood-brain barrier and access the central nervous system? | 2017 | 28622084 | |
| prevalence of multiple drug resistant streptococcus suis in and around guwahati, india. | this study was conducted to determine the prevalence and antimicrobial susceptibility of streptococcus suis and their resistance patterns isolated from both clinically healthy carriers and diseased pigs in and around guwahati, assam, india. | 2017 | 28620262 |
| differences in microbiota membership along the gastrointestinal tract of piglets and their differential alterations following an early-life antibiotic intervention. | early-life antibiotic interventions can change the predisposition to disease by disturbing the gut microbiota. however, the impact of antibiotics on gut microbiota in the gastrointestinal tract is not completely understood, although antibiotic-induced alterations in the distal gut have been reported. here, employing a piglet model, the microbial composition was analyzed by high-throughput 16s rrna gene sequencing and picrust predictions of metagenome function. the present study showed clear spat ... | 2017 | 28536561 |
| potentially hazardous streptococcus suis strains latent in asymptomatic pigs in a major swine production area of thailand. | carrier pigs have been considered as the major reservoir of streptococcus suis and couldbe a significant source of human infection. therefore, we investigated the prevalence and characteristics of latent s. suis in asymptomatic pigs in the pig-farming area of central thailand, and compared the data to those previously reported in other regions. | 2017 | 28516843 |
| draft genome sequence of clinical strain tani1 of streptococcus suis serotype 5 isolated from a bacteremia patient in japan. | streptococcus suis is a swine pathogen that causes severe economic damage to the porcine industry. it occasionally evokes zoonotic infection in humans. here, we report a draft genome sequence of a s. suis serotype 5 strain isolated from a bacteremia patient that was reported by taniyama et al. (d. taniyama, m. sakurai, t. sakai, t. kikuchi, and t. takahashi, idcases 6:36-38, 2016, https://doi.org/10.1016/j.idcr.2016.09.011). | 2017 | 28473377 |
| muramidase-released protein of streptococcus suis: new insight into its impact on virulence. | 2017 | 28467144 | |
| expression and characterization of serotype 2 streptococcus suis arginine deiminase. | arginine deiminase (arca) has been speculated to facilitate the intracellular survival of streptococcus suis under acidic conditions. however, the physical and biological properties and function of ss2-arca have not yet been elucidated. | 2017 | 28456803 |
| evaluation of the immunomodulatory properties of streptococcus suis and group b streptococcus capsular polysaccharides on the humoral response. | streptococcus suis and group b streptococcus (gbs) are encapsulated streptococci causing septicemia and meningitis. antibodies (abs) against capsular polysaccharides (cpss) have a crucial protective role, but the structure/composition of the cps, including the presence of sialic acid, may interfere with the generation of anti-cps ab responses. we investigated the features of the cps-specific ab response directed against s. suis serotypes 2 and 14 and gbs serotypes iii and v after infection or im ... | 2017 | 28425925 |
| streptococcal adhesin p (sadp) contributes to streptococcus suis adhesion to the human intestinal epithelium. | streptococcus suis is a zoonotic pathogen, causing meningitis and septicemia. we previously demonstrated that the gastrointestinal tract (git) is an entry site for zoonotic s. suis infection. here we studied the contribution of streptococcal adhesin protein (sadp) to host-pathogen interaction at git level. | 2017 | 28407026 |
| interaction of factor h-binding protein of streptococcus suis with globotriaosylceramide promotes the development of meningitis. | streptococcus suis is an important emerging zoonotic agent that causes acute bacterial meningitis in humans with high mortality and morbidity. our previous work showed that factor h-binding protein (fhb) contributed to virulence of s. suis, but the role of fhb in the development of s. suis meningitis remained unclear. in this study, we demonstrated for the first time that fhb contributed to the traversal of s. suis across the human blood-brain barrier by allelic-exchange mutagenesis, complementa ... | 2017 | 28402705 |