Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| minimal debridement in the treatment of fournier's gangrene. | scrotal and perineal gangrene of the male genitalia was first described by fournier in 1883. treatment of the disease remains surgical despite the availability of modern antibiotics. many authors advocate a wide debridement of all tissue superficial to the involved fascial layers. we have reviewed our experience of using wide and minimal debridement as the surgical technique of choice. in our retrospective study, nine patients were diagnosed and treated over a 2-year period for fournier's gangre ... | 1999 | 10551751 |
| microbiology of subphrenic abscesses: a 14-year experience. | the objective of the review was to study the aerobic and anaerobic microbiology of subphrenic abscesses in relation with predisposing conditions. a retrospective review of clinical and laboratory data of 52 patients treated between 1974 and 1988 was conducted. forty-three (83%) patients developed the abscesses after an operative procedure. these included 11 patients after colonic, 9 patients after gastric or duodenal, 7 patients after abdominal trauma, 7 patients after biliary, and 6 patients af ... | 1999 | 10551755 |
| [acute infectious mastoid complications in infancy]. | the incidence of acute mastoiditis accounts for 0.004% of acute middle otitis. nowadays there is a decrease of number of mastoiditis and its complications, but from time to time are seen outbreaks without logical explanation of facts. we report 4 clinical cases of acute mastoiditis complicated with subperiosteal abscess, in children between 8 and 23 month old, seen at our department during the last 3 years, three of them diagnosed in a 4-month term. | 1999 | 10568306 |
| misleading diagnosis of retroperitoneal actinomycosis. | a 34-year-old woman presented with a left-sided suprarenal space-occupying lesion on sonography. culture of material obtained during sonographic-guided puncture of the retroperitoneal lesion yielded a mixed flora of actinomyces and peptostreptococcus. initially, a misleading diagnosis of an adrenal pheochromocytoma was initiated by highly positive metaiodobenzylguanidine scintigraphy after chemical chemistry vanillylmandelic acid (vma) test showed elevated values for adrenaline and its derivativ ... | 1999 | 10602965 |
| susceptibility of anaerobic bacteria in auckland: 1991-1996. | to determine the antimicrobial susceptibility of local anaerobic bacteria. | 1999 | 10678225 |
| bacterial interference in the nasopharynx and nasal cavity of sinusitis prone and non-sinusitis prone children. | the aim of this study was to compare the frequency of recovery of potential pathogens and aerobic and anaerobic interfering bacteria in the nasopharynx and nasal cavity of sinusitis prone (sp) children, with their recovery in non-sinusitis prone (n-sp) children. nasopharyngeal and nasal cultures were taken from 20 sp and 20 n-sp children. potential pathogens and aerobic and anaerobic bacteria with interfering capabilities against these micro-organisms were identified. twenty-one potential pathog ... | 1999 | 10687943 |
| [results of treatment of deep neck abscesses and phlegmons]. | neck, as a structure very closely connected with oral cavity and pharynx, with great number of lymph nodes, (about 2, 3 of all are in the neck), is sometimes a localization of purulent inflammatory process but its incidence is not so high as the incidence of inflammations of surrounding organs and tissue. deep neck abscesses are localized under the upper fascial layer. they have a serious clinical picture which could be further complicated if inflammation spreads on vessels or neck organs. if th ... | 1999 | 10624393 |
| robustness of protein folding kinetics to surface hydrophobic substitutions. | we use both combinatorial and site-directed mutagenesis to explore the consequences of surface hydrophobic substitutions for the folding of two small single domain proteins, the src sh3 domain, and the igg binding domain of peptostreptococcal protein l. we find that in almost every case, destabilizing surface hydrophobic substitutions have much larger effects on the rate of unfolding than on the rate of folding, suggesting that nonnative hydrophobic interactions do not significantly interfere wi ... | 1999 | 10631990 |
| quinupristin/dalfopristin: a review of its use in the management of serious gram-positive infections. | quinupristin/dalfopristin is the first parenteral streptogramin antibacterial agent, and is a 30:70 (w/w) ratio of 2 semisynthetic pristinamycin derivatives. the combination has inhibitory activity against a broad range of gram-positive bacteria including methicillin-resistant staphylococci, vancomycin-resistant enterococcus faecium (vref), drug-resistant streptococcus pneumoniae, other streptococci, clostridium perfringens and peptostreptococcus spp. the combination also has good activity again ... | 1999 | 10651391 |
| cloning of fiba, encoding an immunogenic subunit of the fibril-like surface structure of peptostreptococcus micros. | although we are currently unaware of its biological function, the fibril-like surface structure is a prominent characteristic of the rough (rg) genotype of the gram-positive periodontal pathogen peptostreptococcus micros. the smooth (sm) type of this species as well as the smooth variant of the rg type (rgsm) lack these structures on their surface. a fibril-specific serum, as determined by immunogold electron microscopy, was obtained through adsorption of a rabbit anti-rg type serum with excess ... | 1999 | 10198013 |
| coaggregation of candida dubliniensis with fusobacterium nucleatum. | the binding of microorganisms to each other and oral surfaces contributes to the progression of microbial infections in the oral cavity. candida dubliniensis, a newly characterized species, has been identified in human immunodeficiency virus-seropositive patients and other immunocompromised individuals. c. dubliniensis phenotypically resembles candida albicans in many respects yet can be identified and differentiated as a unique candida species by phenotypic and genetic profiles. the purpose of ... | 1999 | 10203506 |
| adherence of peptostreptococcus micros morphotypes to epithelial cells in vitro. | peptostreptococcus micros, which is associated with oral and non-oral mixed anaerobic infections, occurs in three colony morphotypes, the smooth type, the rough type and the smooth variant of the rough type. these types differ in surface structures; the rough type expresses large fibrillar surface appendages, which are absent on the surface of both the smooth and the smooth variant of the rough type. to determine the role of these surface structures in adherence we characterized the adherence of ... | 1999 | 10204480 |
| coagulase-negative staphylococci are the most common bacteria found in cultures from the deep portions of hidradenitis suppurativa lesions, as obtained by carbon dioxide laser surgery. | the significance of bacterial findings in hidradenitis suppurativa (hs) is controversial. interpretation of the results of bacteriological examinations from the surface of hs lesions is obscured by the possible contamination of resident skin bacteria. bacteriological analysis of aspirates from deeper parts of hs is liable to show low sensitivity. we used a carbon dioxide (co2) laser method to evaporate the diseased tissue level by level from the surface downwards, allowing concurrent sampling of ... | 1999 | 10215774 |
| metronidazole susceptibility testing of anaerobic bacteria associated with periodontal disease. | the aim of the present investigation was to determine the susceptibility of prevotella intermedia, porphyromonas gingivalis, fusobacterium and peptostreptococcus micros to metronidazole in vitro. two methods were applied on each isolated strain: agar dilution and epsilometer etest. a total of fifty three wild test strains (13 p.intermedia, 14 p. gingivalis, 14 f.spp and 12 p.micros) were isolated from patients with periodontitis. the etest appears to be a simple, rapid and reliable method for th ... | 1999 | 10223399 |
| in vitro activities of pazufloxacin, a novel injectable quinolone, against bacteria causing infections in obstetric and gynecological patients. | t-3762 is an injectable new quinolone with a broad spectrum of antibacterial activity. pazufloxacin (t-3761) is an active form of t-3762. the minimal inhibitory concentrations (mics) of pazufloxacin for 50% of the clinical isolates tested were 3.13 microg/ml for streptococcus agalactiae, 6.25 microg/ml for gardnerella vaginalis, 0.025 microg/ml for escherichia coli, 0.78 microg/ml for pseudomonas aeruginosa, 6.25 microg/ml for peptostreptococcus magnus, 6.25 microg/ml for bacteroides fragilis an ... | 1999 | 10224336 |
| interactions between a single immunoglobulin-binding domain of protein l from peptostreptococcus magnus and a human kappa light chain. | the placement of a tryptophan residue into a single ig-binding-domain of protein l from peptostreptococcus magnus has been used to examine the binding interactions between the binding domain and kappa light chains (kappa-chains). the fluorescence intensity of the mutant domain increases on the formation of a complex with kappa-chains. this has been used to determine the kd of the complex under a range of conditions by using both pre-equilibrium and equilibrium methods. the kd values determined f ... | 1999 | 10229674 |
| bacterial populations contaminating the upper gut in patients with small intestinal bacterial overgrowth syndrome. | small intestinal bacterial overgrowth syndrome (sibos) is characterized by an abnormally high bacterial population level in the upper gut, exceeding 10(5) organisms/ml (5 log colony-forming unit (cfu)/ml). to understand its origin and select an appropriate antibiotic treatment, we have analyzed the bacterial populations contaminating the upper gut in sibos patients. | 1999 | 10235214 |
| the family coriobacteriaceae: reclassification of eubacterium exiguum (poco et al. 1996) and peptostreptococcus heliotrinreducens (lanigan 1976) as slackia exigua gen. nov., comb. nov. and slackia heliotrinireducens gen. nov., comb. nov., and eubacterium lentum (prevot 1938) as eggerthella lenta gen. nov., comb. nov. | 16s rrna gene sequences were determined for eubacterium exiguum and peptostreptococcus heliotrinreducens. these species were found to be closely related and, together with eubacterium lentum, to constitute a branch of the coriobacteriaceae. two new genera are proposed on the basis of phenotypic characteristics and 16s rrna gene sequence comparisons: slackia to include the bile-sensitive species eubacterium exiguum and p. heliotrinreducens, and eggerthella to include the bile-resistant eubacteriu ... | 1999 | 10319481 |
| microbiological and clinical effects of a 1% chlorhexidine-gel in untreated periodontal pockets from adult periodontitis patients. | the aim of this study was to report the microbiological and clinical effects of repeated subgingival administration of a 1% chlorhexidine-gel in periodontal pockets from 10 patients with adult periodontitis. results showed that the experimental treatment significantly improved clinical parameters (plaque index, gingival bleeding index, and pocket probing depth). direct subgingival administration of chlorhexidine-gel also produced a remarkable modification in the proportions of putative periodont ... | 1999 | 10322610 |
| prevalence of corynebacterial 16s rrna sequences in patients with bacterial and "nonbacterial" prostatitis. | the etiology of chronic prostatitis syndromes in men is controversial, particularly when positive cultures for established uropathogens are lacking. although identification of bacteria in prostatic fluid has relied on cultivation and microscopy, most microorganisms in the environment, including some human pathogens, are resistant to cultivation. we report here on an rrna-based molecular phylogenetic approach to the identification of bacteria in prostate fluid from prostatitis patients. positive ... | 1999 | 10325338 |
| interference by aerobic and anaerobic bacteria in children with recurrent group a beta-hemolytic streptococcal tonsillitis. | to compare the frequency of recovery of aerobic and anaerobic bacteria with interfering capability of group a beta-hemolytic streptococci (gabhs) in the tonsils of children with and without a history of recurrent gabhs pharyngotonsillitis. | 1999 | 10326813 |
| comparative microbiological characteristics of failing implants and periodontally diseased teeth. | the purpose of this report was to compare the distribution of periodontal pathogens recovered from failing implants and teeth with adult and recurrent forms of periodontitis. | 1999 | 10328655 |
| aerobic and anaerobic microbiology of surgical-site infection following spinal fusion. | the aerobic and anaerobic microbiology of surgical-site infections (ssi) following spinal fusion was retrospectively studied. this was done by reviewing the clinical and microbiological records at the naval hospital in bethesda, md., from 1980 to 1992. aspirates of pus from 25 infection sites showed bacterial growth. aerobic bacteria only were recovered from 9 (36%) specimens, anaerobic bacteria only were recovered from 4 (16%), and mixed aerobic and anaerobic bacteria were recovered from 12 (48 ... | 1999 | 9986872 |
| isolation of fusobacterium necrophorum from cancrum oris (noma). | a study of the predominant microflora in active sites of noma (cancrum oris) lesions was carried out in eight noma patients 3-15 years of age in sokoto state in northwestern nigeria. paper point sampling and conventional anaerobic microbiologic techniques were used. fusobacterium necrophorum was recovered from 87.5% of the noma lesions. oral microorganisms included prevotella intermedia, alpha-hemolytic streptococci, and actinomyces spp. which were isolated from 75.0%, 50.0%, and 37.5% of the pa ... | 1999 | 9988340 |
| elastase activity of anaerobes isolated from amniotic fluid with preterm premature rupture of membranes. | a total of 131 anaerobes isolated from amniotic fluid with preterm premature rupture of membranes and stored were examined for elastolytic activity by the method described by williams et al (lett appl microbiol 1988;7:173-6). | 1999 | 9988804 |
| comparative in vitro activities of amoxicillin-clavulanate against aerobic and anaerobic bacteria isolated from antral puncture specimens from patients with sinusitis. | by an agar dilution method, the antimicrobial susceptibilities of antral sinus puncture isolates were studied. pneumococci were generally susceptible to amoxicillin, azithromycin, and clarithromycin, but 17% of pneumococcal isolates were resistant to cefuroxime. haemophilus influenzae isolates were resistant to amoxicillin and clarithromycin. beta-lactamase production occurred in 69% of prevotella species. one-third of peptostreptococcus magnus isolates were resistant to azithromycin and clarith ... | 1999 | 10049296 |
| relationship of the subgingival microbiota to a chairside test for aspartate aminotransferase in gingival crevicular fluid. | the aim of the present study was to evaluate the association between the occurrence of certain specific periodontal pathogens and aspartate aminotransferase (ast) levels in gingival crevicular fluid (gcf). | 1999 | 10052771 |
| infections associated with dental procedures in total hip arthroplasty. | dental procedures may lead to a transient bacteraemia lasting for up to 30 minutes. of the numerous cases of total hip arthroplasty (tha) reported which have been infected from haematogenous sources, dental procedures have been involved only infrequently. we reviewed the records of 2973 patients after tha. of the late infections identified in 52 patients, three (6%) were strongly associated with a dental procedure. infection was diagnosed by culture from the affected joint; streptococcus viridan ... | 1999 | 10068004 |
| infection after rotator cuff repair. | sixteen patients (15 men and 1 woman) were treated for infection complicating rotator cuff repair during the period 1975 through 1994. eight of the 16 patients had their initial procedure performed elsewhere. the remaining 8 procedures were performed at our institution with the known incidence of this complication being 0.27%. in addition to intravenous antibiotic therapy, an average of 3.5 (range 2 to 8) operative procedures were required to eradicate the infections. micro-organisms cultured we ... | 1999 | 10077787 |
| clinical and microbiological characteristics of smokers with early onset periodontitis. | cigarette smoking is a potential risk factor which has recently been associated with periodontal disease progression. the objective of this study was to compare the microbial profile of smokers and non-smokers in a group of patients with early onset periodontitis. the study population consisted of 60 healthy individuals, 40 males and 20 females aged 22 to 35 yr, exhibiting early onset periodontitis. thirty patients were smokers (30.9 cigarettes/d) and 30 non-smokers. smokers had a higher proport ... | 1999 | 10086883 |
| the microbiota of periodontal pockets with different depths in therapy-resistant periodontitis. | this study presents the composition of the cultivable microbiota colonising periodontal pockets of different depths among 2 patient-groups classified as non-responsive (nr-group; 11 participants) or responsive (r-group; 10 participants) to periodontal treatment. microbiological samples from three types of pocket (< 4 mm deep a-samples; 4-5 mm b-samples; > 5 mm c-samples) were analysed by cultural methods for putative periodontitis pathogens, microbial groups constituting > or = 5% of the total c ... | 1999 | 10100039 |
| microbiota of successful osseointegrated dental implants. | the long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. this study examined the impact on the peri-implant microbiota of crown restorations; implant type; length of time of loading; history of implant or periodontal infections; and whether implants replaced single or multi ... | 1999 | 10102550 |
| in vitro antibacterial properties of pexiganan, an analog of magainin. | pexiganan, a 22-amino-acid antimicrobial peptide, is an analog of the magainin peptides isolated from the skin of the african clawed frog. pexiganan exhibited in vitro broad-spectrum antibacterial activity when it was tested against 3,109 clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria. the pexiganan mic at which 90% of isolates are inhibited (mic90) was 32 micrograms/ml or less for staphylococcus spp., streptococcus spp., enterococcus faecium, corynebacteriu ... | 1999 | 10103181 |
| comparative activity of eighteen antimicrobial agents against anaerobic bacteria isolated in south africa. | the in vitro activity of 18 antimicrobial agents was determined against 378 anaerobic bacteria isolated in bloemfontein, south africa, during 1996/97. against the gram-positive isolates, mics of penicillin and cefoxitin were >0.5 microg/ml and >16 microg/ml, respectively, for five and three strains of non-perfringens clostridium spp. seventeen peptostreptococcus anaerobius strains were resistant to penicillin (mic > or = 2 microg/ml). all gram-positive anaerobes tested except one peptostreptococ ... | 1999 | 10192714 |
| differential induction of colitis and gastritis in hla-b27 transgenic rats selectively colonized with bacteroides vulgatus or escherichia coli. | resident bacteria play an important role in initiating and perpetuating gastrointestinal inflammation. we previously demonstrated that six commensal bacteria including bacteroides vulgatus caused more aggressive colitis and gastritis in hla-b27 transgenic rats than did the other five bacteria without b. vulgatus. this study compared the degree of gastrointestinal inflammation in gnotobiotic hla-b27 transgenic rats monoassociated with either b. vulgatus or escherichia coli. gnotobiotic transgenic ... | 1999 | 10338507 |
| effects of hydrogen peroxide on growth and selected properties of porphyromonas gingivalis. | in this study we first evaluated the effects of hydrogen peroxide (h2o2) on growth and selected properties of porphyromonas gingivalis, and compared them with those obtained by a reducing agent (cysteine). the growth of p. gingivalis was only moderately affected when h2o2 was added at concentrations up to 30 mm in a complex culture medium. however, when a defined basal medium was used, h2o2 at a concentration of 3 mm completely inhibited growth of p. gingivalis. incorporation of cysteine at conc ... | 1999 | 10339828 |
| [multiple abscesses (cerebral, splenic, cutaneous) and pulmonary infection]. | 1999 | 10365514 | |
| antibiotic susceptibility of putative periodontal pathogens in advanced periodontitis patients. | in the present study, the antibiotic susceptibility of most prevalent micro-organisms in advanced periodontitis patients was evaluated. in 56 patients, pooled subgingival plaque samples were taken from the deepest site of each quadrant and were cultivated anaerobically. from each patient, the 4 most frequently encountered types of bacterial colonies were subcultured and identified (rapid id 32 a). from all bacterial species identified in the 224 subcultures, the 4 most prevalent were used for su ... | 1999 | 10382573 |
| flow cytometry to monitor phagocytosis and oxidative burst of anaerobic periodontopathogenic bacteria by human polymorphonuclear leukocytes. | the reduced susceptibility to phagocytosis found among some periodontopathogenic anaerobes may account for the differences between invasive and non-invasive strains. we applied flow cytometry as a powerful tool to analyze and quantify phagocytosis using standardized cultures of oral anaerobes (porphyromonas gingivalis, prevotella intermedia, p. nigrescens, capnocytophaga gingivalis, c. ochracea, c. sputigena, fusobacterium nucleatum and peptostreptococcus micros) and heparinized whole blood. bac ... | 1999 | 10384401 |
| inflammatory mediators in saliva of patients with rapidly progressive periodontitis during war stress induced incidence increase. | rapidly progressive periodontitis (rpp) results from the interaction between the periodontal microflora and the host. stress is believed to play an important role in determining host responses, and it has been proposed that hyperactivity of host defense mechanisms significantly increases tissue destruction typical for this disease. during a period of four months we have diagnosed 20 patients with acute rpp, all of them active participants in battles of the croatian liberation war with posttrauma ... | 1999 | 10402713 |
| microbiology of retroperitoneal abscesses in children. | samples of pus from 41 children with retroperitoneal abscess treated between 1974 and 1994 yielded a total of 125 organisms (3.0 isolates/specimen); 58 isolates were aerobic and facultative species (1.4/specimen) and 67 were anaerobic (1.6/specimen). aerobic bacteria only were isolated from 7 (17%) abscesses, anaerobic bacteria only from 3 (7%) and mixed aerobic and anaerobic bacteria from 31 (76%); 34 (83%) infections were polymicrobial. the predominant aerobic and facultative isolates were esc ... | 1999 | 10403422 |
| destructive knee joint infection caused by peptostreptococcus micros: importance of early microbiological diagnosis. | peptostreptococcus micros is a commensal of the oral cavity and the genitourinary tract that rarely causes serious infections. a case of a destructive knee joint infection with rapid progress caused by p. micros is presented. the significance of the microbiological findings was initially not acknowledged, which contributed to a nonsuccessful clinical outcome. | 1999 | 10405436 |
| clinical and microbiological effects of initial periodontal therapy in conjunction with amoxicillin and clavulanic acid in patients with adult periodontitis. a randomised double-blind, placebo-controlled study. | the aim of the present study was to investigate the clinical and microbiological effects of initial periodontal therapy in conjunction with systemic amoxicillin plus clavulanic acid in adult periodontitis patients using a double-blind, parallel-group, and placebo-controlled protocol. 21 patients with a clinical diagnosis of generalised adult periodontitis were recruited. clinical measurements and microbiological assessments were carried out at baseline, 3, and 12 months post-treatment. approxima ... | 1999 | 10412851 |
| bacteremia after dental treatment in mentally handicapped people. | bacteremia may occur after disruption of the oral mucous membrane, particularly after dental treatment. 18 mentally handicapped patients who underwent dental treatment with general anesthesia were included in our study. none of the patients had general illnesses or received antibiotic protection. from each patient several blood samples were drawn aseptically during dental treatment and cultured. the majority of aerobic bacteria recovered belonged to streptococcus sp and gemella sp., anaerobic ba ... | 1999 | 10412852 |
| porphyromonas gingivalis prevalence related to other micro-organisms in adult refractory periodontitis. | forty-six adult periodontal patients, selected on the basis of clinical examination, and 46 adult healthy subjects were examined. the subgingival plaque samples from one inflammatory and one non-inflammatory site of each periodontal patient were studied to determine porphyromonas gingivalis prevalence related to other periodontal micro-organisms and to periodontal tissue destruction. the results showed porphyromonas gingivalis as the main pathogenic micro-organism isolated in the inflammatory si ... | 1999 | 10423739 |
| periodontitis associated bacteria in supragingival plaque of dental hygienists: stability of carrier state and clinical development. | the purpose of this study was the clinical and microbiological re-examination of dental hygienists, who, 30 months before, had shown remarkably high supragingival levels of periodontitis-associated micro-organisms. interdental plaque was collected from the same molar sites and investigated by the same immunofluorescence assay with taxa-specific monoclonal antibodies as at the initial examination. on average, the 15 re-examined subjects showed slightly increased plaque levels but unchanged bleedi ... | 1999 | 10424388 |
| activity of telithromycin (hmr 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. | time-kill studies examined the activities of telithromycin (hmr 3647), erythromycin a, azithromycin, clarithromycin, roxithromycin, clindamycin, pristinamycin, amoxicillin-clavulanate, and metronidazole against 11 gram-positive and gram-negative anaerobic bacteria. time-kill studies were carried out with the addition of oxyrase in order to prevent the introduction of co(2). macrolide-azalide-ketolide mics were 0.004 to 32.0 microg/ml. of the latter group, telithromycin had the lowest mics, espec ... | 1999 | 10428930 |
| [trovafloxacin in gynecology]. | presence of microorganisms in the female lower genital tract (lgt) in concentrations that modify the established normal equilibrium produce different symptoms that make necessary to consult the gynecologist. it is currently accepted that infections of the lgt are due to microorganisms that are normally integrating the internal flora, except for the erroneously called "sexually transmitted diseases" that are caused by external microorganisms. this means that all those microorganisms usually prese ... | 1999 | 10436555 |
| cervical necrotizing fasciitis: 10 years' experience at a single institution. | to evaluate clinical and microbiologic characteristics, modalities of treatment and outcome of patients with cervical necrotizing fasciitis admitted to our institution. | 1999 | 10447540 |
| infection-stimulated infraosseus inflammation and bone destruction is increased in p-/e-selectin knockout mice. | infections of the dental pulp commonly result in infraosseus inflammation and bone destruction. however, the role of phagocytic leucocytes in the pathogenesis of pulpal infections has been uncertain. in this work we used p/e-/- selectin-deficient mice, which lack rolling adhesion of leucocytes to endothelium and mimic the human syndrome, leucocyte adhesion deficiency ii (lad-ii), to test the hypothesis that phagocytic leucocytes protect against pulpal infection and subsequent periapical infraoss ... | 1999 | 10447722 |
| in vitro activity of gemifloxacin (sb 265805) against anaerobes. | gemifloxacin mesylate (sb 265805), a new fluoronaphthyridone, was tested against 359 recent clinical anaerobic isolates by the national committee for clinical laboratory standards reference agar dilution method with supplemented brucella blood agar and an inoculum of 10(5) cfu/spot. comparative antimicrobials tested included trovafloxacin, levofloxacin, grepafloxacin, sparfloxacin, sitafloxacin (du-6859a), penicillin g, amoxicillin clavulanate, imipenem, cefoxitin, clindamycin, and metronidazole ... | 1999 | 10471570 |
| [bacteria isolated from surgical infections and their susceptibilities to antimicrobial agents: special references to bacteria isolated between july 1996 and june 1997]. | the annual multicenter studies on isolated bacteria from infections in general surgery and their antimicrobial susceptibility have been conducted in 20 facilities in japan since july 1982. this paper describes the results obtained during period from july 1996 to june 1997. the number of cases investigated as objectives was 217 for one year. a total of 406 strains were isolated from 177 cases (81.6% of total cases). from primary infections 162 strains were isolated, and from postoperative infecti ... | 1999 | 10480049 |
| [in vitro bactericidal activities of new oral penem, faropenem against the various clinical isolates]. | the minimum inhibitory concentration (mic) and minimum bactericidal concentration (mbc) of faropenem (frpm) more compared with those of various oral beta-lactams against 15 isolates each of 6 species of microorganism. frpm possessed potent in vitro antibacterial activity against both aerobic and anaerobic gram-positive bacteria tested. frpm showed the same activity as new oral cephems such as cefdinir, cefditoren and cefcapene against all gram-negative bacteria, but k. pneumoniae strains were le ... | 1999 | 10480050 |
| [clinical evaluation of anaerobic infections in patients with bronchopulmonary infections diagnosed by transtracheal aspiration]. | we evaluated the clinical and bacteriologic features in the patients with bronchopulmonary infections isolated anaerobes from transtracheal aspirates between april 1990 and march 1998. some anaerobe was isolated in 42 (10.9%) in 387 patients whom we performed transtracheal aspiration (tta), in 42 (15.7%) of 268 in whom some organism was isolated from tta, or in 42 (16.3%) of 257 patients in whom some bacterium excluding acid-fast bacteria, fungi or mycoplasma from tta. the isolation rate of anae ... | 1999 | 10481403 |
| microbiological features of papillon-lefèvre syndrome periodontitis. | papillon-lefevre syndrome patients exhibit hyperkeratosis palmo-plantaris and severe periodontitis. the syndrome is an autosomal recessive trait, but the mechanism of periodontal destruction is not known. this report presents the clinical and microbiological features of an 11-year old girl with papillon-lefèvre syndrome. clinical examination included conventional periodontal measurements and radiographic analysis. in samples from 3 deep periodontal lesions, the occurrence of major suspected peri ... | 1999 | 10487314 |
| the microbiology of infected and noninfected leg ulcers. | a clinical study was undertaken to investigate and compare specifically the aerobic and anaerobic microbiology of infected and noninfected leg ulcers. | 1999 | 10487444 |
| microbiology of infected pustular psoriasis lesions. | bacterial infections can occur in lesions of pustular psoriasis (pp). the objective of this study was to establish the aerobic and anaerobic microbiology of secondarily infected pp. | 1999 | 10487445 |
| bacterial vaginosis a "broad overview". | bacterial vaginosis (bv) was first reported in 1995 by gardner and dukes, who described the unique clinical signs and symptoms and the distinctive nature of the vaginal discharge associated with it. they also described a "new" causative organism, which they named "haemophilus vaginalis", subsequently renamed gardnerella vaginalis. bv is currently the most prevalent cause of infectious vaginitis among women attending for genitourinary diseases. bv has a complex microbiology. lactobacillus populat ... | 1999 | 10932748 |
| proteolysis and utilization of albumin by enrichment cultures of subgingival microbiota. | subgingival dental plaque consists mainly of microorganisms that derive their energy from amino acid fermentation. their nutrient requirements are met by the subgingival proteolytic system, which includes proteases from microorganism and inflammatory cells, and substrate proteins from sulcus exudate, including albumin. to determine the selective effect of individual proteins on microbiota, we used albumin as the main substrate for growth. eight subgingval plaque samples from untreated periodonta ... | 1999 | 10895689 |
| [in vitro activities of levofloxacin and other antibiotics against fresh clinical isolates]. | in this study, the in vitro activity of levofloxacin (lvfx) against 1,020 fresh bacterial clinical isolates was compared with the activities of a range of ofloxacin, ciprofloxacin (cpfx), ampicillin (abpc), cefaclor, cefpodoxime, methicillin and benzylpenicillin. the clinical isolates except vibrio cholerae were collected in japan during 1998 from patients with infectious diseases. mics were determined using the agar dilution method according to the recommendations by the japan society of chemot ... | 1999 | 10746192 |
| [the clinical picture, treatment and prognosis of meningitis due to anaerobic and nonfermentative bacteria]. | the study of incidence, clinical manifestations and prognosis of meningitis with anaerobic and non-fermentative bacteria. | 1999 | 10756944 |
| response of the central metabolism in corynebacterium glutamicum to the use of an nadh-dependent glutamate dehydrogenase. | the extensive use of 13c enrichments in precursor metabolites for flux quantification does not rely on nadph stoichiometries and can therefore be used to quantify reducing power fluxes. as an application of this concept, the nadph fluxes were quantified in an l-lysine producer of corynebacterium glutamicum grown into metabolic and isotopic steady state with [1-13c]glucose. in this case, where the organism's nadph-dependent glutamate dehydrogenase consumes reducing power, the nadph flux generated ... | 1999 | 10935753 |
| [anaerobic bacterial analysis of 436 specimens of clinical infection]. | this study was aimed at the relationship between anaerobes and clinical infection. aerobic and anaerobic bacterial culture was performed for 436 specimens of clinical infection. the incidence of anaerobic bacteria isolates and predominant species were analyzed. the results showed that the incidence of anaerobic isolates was 88.3% (385/436), the main predeminoue species were gram negative nonsporeforming anaerobic rods (bacteroids, prevotella and porphyromonas) and peptostreptococcus. the endogen ... | 1999 | 12205907 |
| [the treatment of bacterial vaginosis with dalacin v cream]. | to asses the efficiency of the 2% clindamycin phosphate creme given in 3 and 7 daily courses officially designer for the treatment of bacterial vaginosis (bv). | 2000 | 10948619 |
| comparative in vitro activities of abt-773 against aerobic and anaerobic pathogens isolated from skin and soft-tissue animal and human bite wound infections. | we studied the comparative in vitro activities of abt-773, a new ketolide, against 268 aerobic and 148 anaerobic recent isolates from clinical bites using an agar dilution method and inocula of 10(4) cfu/spot for aerobes and 10(5) cfu for anaerobes. the following are the mic ranges and mics at which 90% of isolates are inhibited (mic(90)s) of abt-773 for various isolates, respectively: pasteurella multocida and pasteurella septica, 0.125 to 2 and 1 microg/ml; other pasteurella species, 0.125 to ... | 2000 | 10952607 |
| aerobic and anaerobic microbiology in intra-abdominal infections associated with diverticulitis. | the aerobic and anaerobic microbiology of intra-abdominal infections associated with diverticulitis was studied in 110 specimens from the peritoneal cavity after intestinal perforation and in 22 specimens from abdominal abscesses. anaerobic bacteria only were isolated from 17 (15%) of the peritoneal specimens, aerobic bacteria only from 12 (11%) and mixed aerobic and anaerobic flora from 81 (74%). a total of 339 bacterial isolates was detected in peritoneal cultures (3.1 per specimen), comprisin ... | 2000 | 10966232 |
| profile of subgingival microbiota in children with mixed dentition. | a diversity of microbial species has been detected in children's oral flora at an early age. to investigate the composition of the subgingival microbiota of different groups of teeth in children with mixed dentition, 40 systemically healthy children, aged 7-8 years, randomly chosen, were examined. subgingival plaque samples were taken from the mesiobuccal sites of 21, 41, 16 and 36 permanent teeth and 53, 73, 64 and 84 deciduous teeth. the samples were cultured for bacterial isolation anaerobica ... | 2000 | 11155173 |
| in vitro activity of an evernimicin derivative, sch27899, against anaerobic bacteria and propionibacterium acnes. | the in vitro activity of sch27899, a novel oligosaccharide antimicrobial agent, was compared with those of representatives of six classes of antimicrobial agents (piperacillin, clarithromycin, clindamycin, vancomycin, sitafloxacin and metronidazole) against clinical isolates of anaerobic bacteria and propionibacterium acnes. against peptostreptococcus: spp. and clostridium difficile, sch27899 was the most potent (mic(90) < 0.125 mg/l) of the agents examined. besides these gram-positive anaerobes ... | 2000 | 10980176 |
| in vitro and in vivo antibacterial activities of a new injectable carbapenem, s-4661, against gynaecological pathogens. | carbapenems are often used to treat infections in obstetrics and gynaecology because of their activity against anaerobes. s-4661, a new injectable carbapenem antibiotic, has favourable pharmacokinetic properties and is not hydrolysed by dehydropeptidase i. we investigated the in vitro and in vivo antibacterial activities of s-4661 against strains of streptococcus agalactiae, escherichia coli, peptostreptococcus magnus, bacteroides fragilis and prevotella bivia, which are major pathogens in the f ... | 2000 | 10980177 |
| characterization of peptostreptococcus species in skin infections. | we examined the characteristics of peptostreptococcus species in infectious skin diseases. p. magnus was the species identified most frequently, followed by p. asaccharolyticus. peptostreptococcus species were mainly isolated from infected atheroma and secondary infections due to ulcers; their resistance to five antimicrobial agents was generally low. the resistance of the three predominant peptostreptococcus species to the antimicrobials was similar to that of all of the peptostreptococcus spec ... | 2000 | 10983864 |
| laboratory diagnosis of anaerobic pleuropulmonary infections. | anaerobic organisms play a major role in pleuropulmonary infections. clinical manifestations range from simple aspiration to acute, severe, necrotizing pneumonias to chronic infections, such as lung abscess and empyema. implicated pathogens are usually of endogenous origin. laboratory diagnosis of anaerobic pleuropulmonary infections is based on recovering the etiological agent from clinical specimens. appropriate specimens include pleuml fluid, transtracheal aspirates, transthoracic aspirates a ... | 2000 | 10983929 |
| comparative in vitro activities of gar-936 against aerobic and anaerobic animal and human bite wound pathogens. | gar-936 is a new semisynthetic glycylcycline with a broad antibacterial spectrum, including tetracycline-resistant strains. the in vitro activities of gar-936, minocycline, doxycycline, tetracycline, moxifloxacin, penicillin g, and erythromycin were determined by agar dilution methods against 268 aerobic and 148 anaerobic strains of bacteria (including pasteurella, eikenella, moraxella, bergeyella, neisseria, ef-4, bacteroides, prevotella, porphyromonas, fusobacterium, staphylococcus, streptococ ... | 2000 | 10991855 |
| bacterial immunoglobulin superantigen proteins a and l activate human heart mast cells by interacting with immunoglobulin e. | human heart mast cells (hhmc) have been identified in heart tissue, perivascularly, and in the intima of coronary arteries. in vitro activation of isolated hhmc induces the release of vasoactive and proinflammatory mediators (histamine, tryptase, and cysteinyl leukotriene c(4) [ltc(4)]). we investigated the effects of several bacterial proteins on hhmc activation in vitro. hhmc released histamine, tryptase, and ltc(4) in response to staphylococcus aureus cowan 1 and the immunoglobulin (ig)-bindi ... | 2000 | 10992448 |
| b-cell deficiency predisposes mice to disseminating anaerobic infections: protection by passive antibody transfer. | we have previously demonstrated that a high proportion of rag-2 scid knockout mice, which lack t and b cells, develop orofacial abscesses and disseminated infections following pulpal infection, whereas immunocompetent control mice do not. in the present study, we sought to identify the components of the adaptive immune response which contribute to protection against disseminating anaerobic infections and sepsis. for this purpose, various genetically engineered immunodeficient mice were employed, ... | 2000 | 10992465 |
| [tracheopulmonary-subcutaneous fistula associated with anaerobic subcutaneous abscess on mechanical ventilator support in a patient with duchenne muscular dystrophy]. | a 29-year-old japanese man with duchenne muscular dystrophy was placed on a mechanical ventilator support at 23 years of age and admitted to our hospital at 25 years of age. he had severe neck contracture deviated to the left side which resulted in dysphagia and microaspiration. at 29 years of age, he developed left lobar pneumonia accompanied by slight fever, back pain and a foul odor from the patient's sputum. although the patient received broad spectrum antibiotics, pneumonia disseminated to ... | 2000 | 11002735 |
| detection of major putative periodontopathogens in korean advanced adult periodontitis patients using a nucleic acid-based approach. | although extensive microbial analyses have been performed from subgingival plaque samples of periodontitis patients, systematic analysis of subgingival microbiota has not been carried out in a korean population so far. the purpose of this study was to describe the prevalence of major putative periodontopathogens in korean patients by culture-independent methods. | 2000 | 11022767 |
| differences in the composition of the subgingival microbiota of two periodontitis populations of different geographical origin. a comparison between spain and the netherlands. | the purpose of this study was to compare the subgingival microbiota of two geographically distinct patient populations using identical clinical and bacteriological methods. adult patients with a diagnosis of periodontitis were consecutively selected according to pre-defined clinical criteria. microbiological samples were taken from the deepest four sites with bleeding. the samples were plated on blood agar plates, for the determination of the total anaerobic counts and identification of specific ... | 2000 | 11037754 |
| [bacteria isolated from surgical infections and their susceptibilities to antimicrobial agents. special references to bacteria isolated between april 1997 and march 1998]. | the annual multicenter studies on isolated bacteria from infections in general surgery and their antimicrobial susceptibility have been conducted in 19 facilities in japan since july 1982. this paper describes the results obtained during the period from april 1997 to march 1998. the number of cases investigated as objectives was 215 for one year. a total of 420 strains (170 strains from primary infections and 250 strains from postoperative infections) were isolated from 174 cases (80.9% of total ... | 2000 | 11070817 |
| microbiological parameters associated with il-1 gene polymorphisms in periodontitis patients. | polymorphisms in the cluster of il-1 genes have been significantly associated with the severity of adult periodontitis. the purpose of this study was to compare microbiological parameters in il-1 genotype negative and positive adult subjects with a range of periodontitis severities. | 2000 | 11073323 |
| bacterial susceptibility to amoxicillin and potassium clavulanate in advanced periodontitis patients not responding to mechanical therapy. | between 4 and 8% of periodontitis patients are reported to respond poorly to conventional therapy. in these cases, adjunctive use of systemic antibiotics might be a reasonable therapeutic approach. the purpose of this study was to evaluate the effects of systemic amoxicillin/clavulanate as adjunct to periodontal surgery on the predominant subgingival microorganisms in patients not responding to mechanical therapy. furthermore, the bacterial susceptibility to amoxicillin/clavulanate was analyzed ... | 2000 | 11073328 |
| [successful treatment for descending necrotizing mediastinitis: a case report]. | a 21-year-old female was admitted to our hospital because of high fever, neck swelling, and dyspnea. she was diagnosed as descending necrotizing mediastinitis (dnm) extended from odontogenic infection. on the day of admission, she underwent cervical drainage. next day, the ct scan showed an abscess below the tracheal bifurcation and bilateral pleural effusion. mediastinal drainage was performed through a right thoracotomy, and a left thoracic tube was inserted. anaerobic peptostreptococcus was f ... | 2000 | 11079317 |
| bacteriology in disease: failure of a micro-ecological balance? | both aerobic (mainly alpha-haemolytic streptococci) and anaerobic micro-organisms (like prevotella and peptostreptococcus species) are able to interfere with the growth of potential pathogens such as group a beta-haemolytic streptococci, streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis. the present paper reviews the application of this concept of interference with respect to the development of common acute ear-, nose- and throat infections. | 2000 | 11082778 |
| the effects of amoxicillin therapy on skin flora in infants. | in order to determine the effect of amoxicillin therapy on the perineal skin microbial flora in infants, we took quantitative bacterial and fungal cultures of perineal and sternal areas from 25 infants treated with amoxicillin (40 mg/kg/day) for 10 days. specimens were obtained prior to therapy, within 3 days of conclusion of therapy, and 14-16 days later. immediately following therapy, a decline in the number of bacterial isolates occurred on both the perineum (89 to 47) and sternum (84 to 39). ... | 2000 | 11085662 |
| human intestinal bacteria capable of transforming secoisolariciresinol diglucoside to mammalian lignans, enterodiol and enterolactone. | seven metabolites were isolated after anaerobic incubation of secoisolariciresinol diglucoside (1) with a human fecal suspension. they were identified as (-)-secoisolariciresinol (2), 3-demethyl-(-)-secoisolariciresinol (3), 2-(3-hydroxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)butane-1,4-diol (4), didemethylsecoisolariciresinol (5), 2(3-hydroxybenzyl)-3-(3,4-dihydroxybenzyl)butane-1,4-diol (6), enterodiol (7) and enterolactone (8). furthermore, two bacterial strains, peptostreptococcus sp. sdg-1 and ... | 2000 | 11086885 |
| bacteriology of histopathologically defined appendicitis in children. | acute appendicitis is the most common surgical emergency in childhood. however, the pathogenesis and detailed microbiology are obscure. | 2000 | 11099090 |
| apparent culture-negative prosthetic valve endocarditis caused by peptostreptococcus magnus. | in two patients with prosthetic valve endocarditis due to peptostreptococcus magnus, blood cultures in the bact/alert and bactec 9240 systems were signal negative. the capability of the bact/alert system to detect various peptostreptococcus species was assessed. p. magnus and p. anaerobius could not be detected, and subcultures remained negative. the growth in conventional media of these two species and other peptostreptococcus species was similar. | 2000 | 11101611 |
| transgenic rainbow trout expressed sgnrh-antisense rna under the control of sgnrh promoter of atlantic salmon. | a recombinant vector containing antisense dna complementary to atlantic salmon (salmo salar) sgnrh cdna driven by specific promoter pab derived from a corresponding sgnrh gene was introduced into rainbow trout (oncorhynchus mykiss) eggs. this resulted in transgenic animals that had integrated one copy of the transgene into their genome and transmitted it through the germline. antisense-sgnrh mrna (as) was expressed mainly in the brain of transgenic as(+) fish. levels of sgnrh endogenous mrna in ... | 2000 | 11116212 |
| aerobic and anaerobic microbiology of wound infection following spinal fusion in children. | to study the aerobic and anaerobic microbiology of wound infections following spinal fusion in children. | 2000 | 10765134 |
| an experimental mouse model to study the pathogenicity of prevotella bivia and investigations of possible virulence. | induction of subcutaneous abscesses in mice was used to study the pathogenicity of prevotella bivia both in mono-infection and in mixed cultures with escherichia coli and peptostreptococcus spp. virulence factors such as coaggregation and aggregate formation of cells, haemagglutination activity and tolerance to serum bactericidal activity were investigated for their possible role in p bivia pathogenicity. monocultures of p bivia, e coli and peptostreptococcus spp did not induce subcutaneous absc ... | 2000 | 10786446 |
| profile of subgingival microbiota in children with primary dentition. | eruption of primary teeth has a great influence on the oral environment by providing suitable niches for bacterial colonization. the aim of the study was to investigate the composition of the subgingival microbiota of primary incisors, canines and molars in 40 systemically healthy children aged 4-5 yr, chosen randomly. subgingival plaque samples were taken from the mesiobuccal sites of primary incisors (61, 81), canines (53, 73) and molars (64, 84). the samples were cultured for bacterial isolat ... | 2000 | 10791707 |
| dynamics of nasopharyngitis in children. | our goal was to characterize the dynamics and bacterial interaction of the aerobic and anaerobic flora of nasal discharge of children at different stages of uncomplicated nasopharyngitis. methods and patients: serial semiquantitative nasopharyngeal (np) and quantitative nasal discharge (nd) cultures were taken every 3 to 5 days from 20 children in whom purulent discharge eventually developed (group 1), and a single culture was obtained from a group of 20 who had only clear discharge (group 2). | 2000 | 10793349 |
| comparative activity of moxifloxacin in vitro against obligately anaerobic bacteria. | the antimicrobial activity of moxifloxacin and seven other antibiotics (four of them quinolones) against 292 strains of obligately anaerobic bacteria was assessed employing a broth microdilution technique performed in wilkens-chalgren broth. mic50/mic90 values (mg/l) for moxifloxacin were as follows: bacteroides fragilis (n = 62) 0.25/2, bacteroides ovatus (n = 70) 1/4, bacteroides vulgatus (n = 29) 0.25/1, bacteroides thetaiotaomicron (n = 17) 2/2, bacteroides caccae (n = 11) 1/2, prevotella sp ... | 2000 | 10795599 |
| synergic activity, for anaerobes, of trovafloxacin with clindamycin or metronidazole: chequerboard and time-kill methods. | chequerboard titrations were used to test the activity of trovafloxacin, alone and in combination with clindamycin or metronidazole, against 156 gram-positive or gram-negative anaerobes, including 47 bacteroides fragilis group, 36 prevotella spp., 26 fusobacteria, 21 peptostreptococci and 26 clostridia. mic50/mic90 values (mg/l) of each drug alone against all 156 strains were: trovafloxacin, 0.5/1; clindamycin, 0.25/2; metronidazole, 1/2. synergy (fic indices </= 0.5) was seen in two strains wit ... | 2000 | 10797085 |
| translocation of indigenous microflora in an experimental model of sepsis. | translocation of viable bacteria from gut to bloodstream and other sterile body sites during shock has been demonstrated in several experimental and clinical studies. the factors causing translocation and its incidence at different stages of shock are not known. the aim of the study was to evaluate the importance of several factors causing translocation of indigenous microflora in an experimental model of septic shock based on intraperitoneal escherichia coli sepsis in rats. counts of inoculated ... | 2000 | 10798556 |
| a breakdown of symmetry in the folding transition state of protein l. | the 62 residue igg binding domain of protein l consists of a central alpha-helix packed on a four-stranded beta-sheet formed by n and c-terminal beta-hairpins. the overall topology of the protein is quite symmetric: the beta-hairpins have similar lengths and make very similar interactions with the central helix. characterization of the effects of 70 point mutations distributed throughout the protein on the kinetics of folding and unfolding reveals that this symmetry is completely broken during f ... | 2000 | 10801362 |
| linezolid. | linezolid is an oxazolidinone antibacterial agent that acts by inhibiting the initiation of bacterial protein synthesis. cross-resistance between linezolid and other inhibitors of protein synthesis has not been demonstrated. linezolid has a wide spectrum of activity against gram-positive organisms including methicillin-resistant staphylococci, penicillin-resistant pneumococci and vancomycin-resistant enterococcus faecalis and e. faecium. anerobes such as clostridium spp., peptostreptococcus spp. ... | 2000 | 10804037 |
| [otogenic cerebral abscess: a persistent problem]. | a young man with otitis media and cholesteatoma of the left ear developed secondary cerebral abscess. the clinical debut was non-specific, with headache, mild fever, and mild persistent otalgia in spite of early antibiotic treatment. studies revealed a cerebral abscess, so ent surgery in collaboration with the neurosurgery department was decided. this case illustrates that clinical manifestations in such cases can be mild and highlights the need to exclude this type of serious pathology. | 2000 | 10804119 |
| in vitro inhibition of commercial douche products against vaginal microflora. | recently, vaginal douching has been associated with many health risks in women. the aim of this study was to analyze the effect of commercial douche products against various vaginal microorganisms, including lactobacilli. seven commercial douches were tested against eight lactobacillus clinical isolates and three type strains from the american type culture collection. bv-associated bacteria included six strains of five genera: gardnerella, mobiluncus, mycoplasma, peptostreptococcus, and ureaplas ... | 2000 | 10805365 |
| microbiology of infected poison ivy dermatitis. | we report the aerobic and anaerobic microbiology of secondarily infected poison ivy dermatitis. the study involved retrospective review of clinical and microbiology laboratory records of patients with secondarily infected poison ivy lesions. bacterial growth was noted in 33 specimens. aerobic or facultative anaerobic bacteria only were present in 18 (55%) patients, anaerobic bacteria only in seven (21%), and mixed anaerobic-aerobic bacteria in eight (24%). forty-five isolates were recovered (1.4 ... | 2000 | 10809852 |
| [what is your diagnosis? bilateral abscess forming pneumonia]. | 2000 | 10815462 |