Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| positive-ion fragmentation in matrix-assisted laser desorption/ionization tandem time of flight mass spectrometry of synthetic analogs of the o-specific polysaccharide of vibrio cholerae o:1. | saccharides (mono- to hexamers) that mimic the terminal epitopes of o-antigens of vibrio cholerae o:1, serotypes ogawa and inaba have been studied by matrix-assisted laser desorption/ionization tandem time-of-flight (maldi tof/tof) mass spectrometry (ms). cationized adducts are the characteristic ions formed through the capture of sodium or potassium cations under maldi ms conditions. three characteristic pathways dominate in the fragmentation of model substances under maldi tof/tof collision-in ... | 2006 | 17057281 |
| the structure of vibrio cholerae extracellular endonuclease i reveals the presence of a buried chloride ion. | the crystal structure of a periplasmic/extracellular endonuclease from vibrio cholerae has been solved at low and at neutral ph. crystals grown at ph 4.6 and 6.9 diffracted to 1.6 a (on bm01a at the esrf) and 1.95 a (on a rotating-anode generator), respectively. the structures of the endonuclease were compared with the structure of a homologous enzyme in v. vulnificus. the structures of the v. cholerae enzyme at different ph values are essentially identical to each other and to the v. vulnificus ... | 2006 | 17057343 |
| traveler's diarrhea. | travelers' diarrhea is common. between 8% and 50% of travelers develop diarrhea; incidence depends on the country visited. the attack rate is highest for travelers from a developed country who visit a developing country. children are at particular risk. travelers' diarrhea is usually acquired through ingestion of fecally contaminated food and water. most cases are due to a bacterial pathogen, commonly, escherichia coli, and occur within the first few days after arrival in a foreign country. more ... | 2006 | 17050494 |
| structural requirements of cholesterol for binding to vibrio cholerae hemolysin. | cholesterol is necessary for the conversion of vibrio cholerae hemolysin (vch) monomers into oligomers in liposome membranes. using different sterols, we determined the stereochemical structures of the vch-binding active groups present in cholesterol. the vch monomers are bound to cholesterol, diosgenin, campesterol, and ergosterol, which have a hydroxyl group at position c-3 (3betaoh) in the a ring and a c-c double bond between positions c-5 and c-6 (c-c delta(5)) in the b ring. they are not bo ... | 2006 | 17053310 |
| rpos controls the vibrio cholerae mucosal escape response. | vibrio cholerae causes a severe diarrhoeal disease by secreting a toxin during colonization of the epithelium in the small intestine. whereas the initial steps of the infectious process have been intensively studied, the last phases have received little attention. confocal microscopy of v. cholerae o1-infected rabbit ileal loops captured a distinctive stage in the infectious process: 12 h post-inoculation, bacteria detach from the epithelial surface and move into the fluid-filled lumen. designat ... | 2006 | 17054394 |
| isolation of vibrio cholerae o1 strains similar to pre-seventh pandemic el tor strains during an outbreak of gastrointestinal disease in an island resort in fiji. | five strains of vibrio cholerae o1, one each from an australian and a new zealand tourist with gastrointestinal illness returning from an island resort in fiji and the remaining three from water sources located in the same resort, were extensively characterized. conventional phenotypic traits that are used for biotyping of o1 v. cholerae categorized all five strains as belonging to the el tor biotype. genetic screening of 11 regions that are associated with virulence in v. cholerae showed variab ... | 2006 | 17030916 |
| genetic characteristics of matlab variants of vibrio cholerae o1 that are hybrids between classical and el tor biotypes. | the matlab variants of vibrio cholerae o1, defined as hybrids between the classical and el tor biotypes, were first isolated from hospitalized patients with acute secretory diarrhoea in matlab, a rural area of bangladesh. these variants could not be categorized as classical or el tor biotypes by phenotypic and genotypic tests, and had representative traits of both the biotypes. a number of virulence-associated genes and/or gene clusters were screened by pcr and dna sequencing. el tor-specific ge ... | 2006 | 17030917 |
| bacterial capsular antigens. structural patterns of capsular antigens. | structural patterns of bacterial capsular antigens including capsular polysaccharides and exoglycans are given in this review. in addition, the immunological activity of capsular antigens and their role in type specificity of bacteria are discussed. | 2006 | 17009947 |
| two soluble pyrophosphatases in vibrio cholerae: transient redundancy or enduring cooperation? | soluble pyrophosphatases (ppases), which are essential for cell life, comprise two evolutionarily unrelated families (i and ii). prokaryotic genomes generally contain a single ppase gene encoding either family i or family ii enzyme. surprisingly, four vibrionales species, including the human pathogen vibrio cholerae, contain ppase genes of both families. here we show that both genes are transcriptionally active in v. cholerae, and encode functional ppases when expressed in escherichia coli. in c ... | 2006 | 17009951 |
| immunogenicity of synthetic saccharide fragments of vibrio cholerae o1 (ogawa and inaba) bound to exotoxin a. | recombinant exotoxin a (repa) from pseudomonas aeruginosa conjugated to vibrio cholerae o1 serotype-specific polysaccharides (mono-, di- and hexasaccharide) were immunogenic in mice. monosaccharide conjugates boosted the humoral responses to the hexasaccharide conjugates. prior exposure to purified ogawa lipopolysaccharide (lps) enabled contra-serotype hexasaccharide conjugates to boost the vibriocidal response, but inaba lps did not prime for an enhanced vibriocidal response by a contra-serotyp ... | 2006 | 17010106 |
| serotype cycles in cholera dynamics. | interest in understanding strain diversity and its impact on disease dynamics has grown over the past decade. theoretical disease models of several co-circulating strains indicate that incomplete cross-immunity generates conditions for strain-cycling behaviour at the population level. however, there have been no quantitative analyses of disease time-series that are clear examples of theoretically expected strain cycling. here, we analyse a 40-year (1966-2005) cholera time-series from bangladesh ... | 2006 | 17015366 |
| 2,3-butanediol synthesis and the emergence of the vibrio cholerae el tor biotype. | vibrio cholerae is an aquatic bacterium that causes the severe diarrheal disease cholera. v. cholerae strains of the o1 serogroup exist as two biotypes, classical and el tor. toxigenic strains of the el tor biotype emerged to cause the seventh pandemic of cholera in 1961 and subsequently displaced strains of the classical biotype both in the environment and as a cause of cholera within a decade. the factors that drove emergence of the el tor biotype and the displacement of the classical biotype ... | 2006 | 17015461 |
| a fluorescent peptide substrate for measuring the adp-ribosylation activity of the cholera toxin a-subunit. | vibrio cholerae serogroups o1 and o139 bengal produce cholera toxin (ct) a typical ab5 bacterial toxin comprising an adp-ribosylation enzyme a-subunit (cta) and a carbohydrate binding b-subunit (ctb). dukoralr the inactivated oral cholera vaccine has recently been licensed for use in the european union. this vaccine contains killed whole cells of v cholerae and 1 mg of purified recombinant ctb (rctb). dukoralr has a good safety profile and there has been no indication that active ct is present. ... | 2006 | 17035737 |
| abundance of pathogenic escherichia coli, salmonella typhimurium and vibrio cholerae in nkonkobe drinking water sources. | in order to study the prevalence of enteric pathogens capable of causing infection and disease in the rural communities of nkonkobe, bacterial isolates were collected from several surface water and groundwater sources used by the community for their daily water needs. by making use of selective culture media and the 20e api kit, presumptive escherichia coli, salmonella spp. and vibrio cholerae isolates were obtained and then analysed by polymerase chain reaction assays (pcr). the pcr successfull ... | 2006 | 17036837 |
| [the cloned ctxa gene of vibrio cholerae expresses in e. coli]. | to construct the expression vector of vibrio cholerae ctxa gene, and realize the vibrio cholerae ctxa gene to express in e. coli, and lay a basis for future research on the immunogenicity and immunoadjuvant. | 2006 | 17037725 |
| outbreak news. acute watery diarrhoeal syndrome, ethiopia. | 2006 | 17039624 | |
| membrane topology mapping of the na+-pumping nadh: quinone oxidoreductase from vibrio cholerae by phoa-green fluorescent protein fusion analysis. | the membrane topologies of the six subunits of na+-translocating nadh:quinone oxidoreductase (na+-nqr) from vibrio cholerae were determined by a combination of topology prediction algorithms and the construction of c-terminal fusions. fusion expression vectors contained either bacterial alkaline phosphatase (phoa) or green fluorescent protein (gfp) genes as reporters of periplasmic and cytoplasmic localization, respectively. a majority of the topology prediction algorithms did not predict any tr ... | 2006 | 17041063 |
| vibrio cholerae non-o1,non-o139 isolated from pleural effusion following total gastrectomy. | we isolated non-o1, non-o139 vibrio cholerae from pleural effusion in a patient with recurred advanced gastric cancer after total gastrectomy. we also recovered the organism from the patient's stool culture. the patient did not experience gastrointestinal symptoms such as diarrhea except heartburn and epigastric discomfort from stomach cancer before admission. the suspected route of infection is directly from the gastrointestinal tract through the previous surgical wounds. after antibiotic treat ... | 2006 | 17043435 |
| lexa represses ctxphi transcription by blocking access of the alpha c-terminal domain of rna polymerase to promoter dna. | ctxphi is a vibrio cholerae-specific temperate filamentous phage that encodes cholera toxin. ctxphi lysogens can be induced with dna damage-inducing agents such as uv light, leading to the release of ctxphi virions and the rapid dissemination of cholera toxin genes to new v. cholerae hosts. this environmental regulation is directly mediated by lexa, the host-encoded global sos transcription factor. lexa and a phage-encoded repressor, rstr, both repress transcription from p(rsta), the primary ctx ... | 2006 | 17046810 |
| an in vitro cell-culture model demonstrates internalin- and hemolysin-independent translocation of listeria monocytogenes across m cells. | an ability to translocate the mucosal epithelia through m cells provides invasive pathogens with a rapid means of accessing the mucosal lymphoid tissues. in order to determine the role of m cells in listeria monocytogenes infection, we initially assessed colonization of peyer's patch (pp) epithelium in balb/c mice by vibrio cholerae eltor, wild-type l. monocytogenes and an isogenic hemolysin mutant (lo28deltahly). it was observed that both wild-type l. monocytogenes and deltahly showed preferent ... | 2006 | 17049432 |
| [analysis of characteristics of major pathogenicity-related genes of vibrio cholerae isolated in guangzhou area from 2001 to 2005]. | to apply multiplex polymerase chain reaction (mpcr) assay and sequencing in study of the carrying status of four pathogenicity-related genes of vibrio cholerae (v.cholerae) and the variation of ctxa. | 2006 | 17097005 |
| interaction of vibrio cholerae o139 with an intestinal parasite, entamoeba histolytica. | 2006 | 17108284 | |
| bacteraemic necrotizing fasciitis with compartment syndrome caused by non-o1 vibrio cholerae. | non-o1 vibrio cholerae are gram-negative rods that can cause sporadic gastroenteritis, bacteraemia, and extraintestinal infections, primarily following the consumption of raw seafood or exposure of damaged skin to contaminated saltwater during the summer months. bacteraemic necrotizing fasciitis caused by non-o1 v. cholerae has rarely been reported. liver cirrhosis, haemochromatosis, and immunosuppression are important factors contributing to the severity of the infections and outcome. this repo ... | 2006 | 17113524 |
| molecular modeling and characterization of vibrio cholerae transcription regulator hlyu. | the smtb/arsr family of prokaryotic metal-regulatory transcriptional repressors represses the expression of operons linked to stress-inducing concentrations of heavy metal ions, while derepression results from direct binding of metal ions by these 'metal-sensor' proteins. the hlyu protein from vibrio cholerae is the positive regulator of haemolysin gene, it also plays important role in the regulation of expression of the virulence genes. despite the understanding of biochemical properties, its s ... | 2006 | 17116251 |
| mechanism-based inhibitors to probe transitional states of glycoside hydrolases. | recent structural and kinetic studies indicate that glycosidases (glycoside hydrolases) change the peripheral structure of their catalytic sites dynamically to trim glycan structures. inhibitors that label specific amino acid residues in the active site of these enzymes based on its mechanism of action are powerful tools to probe such a hidden transitional state. this chapter describes methods of mechanism-based irreversible inhibitors having fluorescence tags, including synthesis, inhibitory as ... | 2006 | 17116476 |
| hidden markov model variants and their application. | markov statistical methods may make it possible to develop an unsupervised learning process that can automatically identify genomic structure in prokaryotes in a comprehensive way. this approach is based on mutual information, probabilistic measures, hidden markov models, and other purely statistical inputs. this approach also provides a uniquely common ground for comparative prokaryotic genomics. the approach is an on-going effort by its nature, as a multi-pass learning process, where each roun ... | 2006 | 17118135 |
| [the development of mucosal vaccines]. | the live oral polio vaccine was the first mucosal vaccine accepted for general use. since then, similar vaccines have been developed against typhoid fever, cholera and rotavirus infection, and a nasal vaccine against influenza has recently been registered in the usa. the only non-living mucosal vaccine on the market today is an oral cholera vaccine consisting of inactivated vibrio cholerae and the b subunit of cholera toxin. several groups of scientists are at present working on the development ... | 2006 | 17086224 |
| disinfection of sludge with high pathogenic content using silver and other compounds. | a physicochemical sludge with high microbial content (10(2)-10(4) fpu/g ts bacteriophages, 10(6)-10(7) mpn/g ts faecal coliforms, 10(4) mpn/g ts salmonella spp., 10(4) mpn/g ts shigella spp., 10(3) mpn/g ts pseudomonas aeruginosa, 10(2) mpn/g ts vibrio cholerae, 10(2)-10(3) cysts/g ts giardia sp., 10(2)-10(4) oocyts/g ts cryptosporidium sp., 168-215 viable helminth ova/g ts) was disinfected using silver, silver-copper, and silver-copper plus a synergistic agent (sa). twenty milligrams ag/g ts in ... | 2006 | 17087384 |
| isolation of vibrio cholerae from the brain of a feedlot heifer with meningoencephalitis. | a 700-pound, 9-month-old angus heifer from a feedlot presented with acute neurologic signs, characterized by circling, posterior weakness, and nonresponsiveness, followed by death. histologically, the frontal lobe and the thalamus contained multiple foci of liquefaction that contained numerous degenerative neutrophils and foamy macrophages. some of these foci were centered on blood vessels that contained fibrin thrombi and exhibited varying degrees of fibrinoid necrosis of the vessel wall. there ... | 2006 | 17121090 |
| a new monoterpene glycoside and antibacterial monoterpene glycosides from paeonia suffruticosa. | antibacterial activity-guided fractionation of the chci3-meoh (1:1) extract of paeonia suffruticosa root bark furnished three monoterpene glycosides, 6-o-vanillyoxypaeoniflorin (1), mudanpioside-h (2), and galloyl-oxypaeoniflorin (3). of the isolated compounds, compound 1 is a new compound. all isolated compounds showed broad, but moderate, antibacterial activity with minimum inhibitory concentration (mic) values in the range of 100 to 500 microg/ml against eighteen pathogenic microorganisms of ... | 2006 | 17121173 |
| review of reported cholera outbreaks worldwide, 1995-2005. | the global temporal and spatial distribution of cholera is underappreciated, given the lack of surveillance in endemic areas and economic disincentives to report outbreaks. to judge the use of specific novel interventions such as vaccines or anti-secretory agents, we compiled a database and analyzed cholera reports from the program for monitoring emerging diseases from 1995 to 2005. of the 632 reports meeting the search criteria, 66% originated in sub-saharan africa, followed by 16.8% from south ... | 2006 | 17123999 |
| incidence of enteric bacterial pathogens in water found at the bottom of commercial freezers in calabar, southeastern nigeria. | bacteriological analysis of water that accumulates at the bottom of freezers in restaurants when the power was cut in calabar, southeastern nigeria, was carried out using standard procedures. mean heterotrophic bacterial counts and escherichia coli counts ranged from 3.1 +/- 0.02 to 7.1 +/- 0.30 x 10(4) cfu/ml and 0.2 +/- 0.10 to 0.6 +/- 0.50 x 10(4) cfu/ml, respectively, indicating heavy bacterial contamination whose source was mostly fecal. there was no significant difference (p > 0.05, 0.01) ... | 2006 | 17125005 |
| vaccines against traveler's diarrhoea and rotavirus disease - a review. | diarrheal diseases constitute one of the most important health problems worldwide, preferentially in developing countries with a morbidity of estimated 5 billion and a mortality of 5 million cases per year. children less than 5 years are particularly in danger with respect to the incidence and severity of the gastrointestinal symptoms. travelers to developing countries are also at risk to develop diarrheal disorders; around 30-50% of them acquire so called "travelers's diarrhea" caused by bacter ... | 2006 | 17131234 |
| breast milk reduces the risk of illness in children of mothers with cholera: observations from an epidemic of cholera in guinea-bissau. | a protective effect of breastfeeding against cholera has been demonstrated in areas endemic of cholera. to assess the protection offered by breast milk from mothers living in an area that had been free from cholera for 7 years, we investigated mothers with cholera and their children during an epidemic with vibrio cholerae el tor in the capital of guinea-bissau. | 2006 | 17133163 |
| endogenous mmtv proviruses induce susceptibility to both viral and bacterial pathogens. | most inbred mice carry germline proviruses of the retrovirus, mouse mammary tumor virus (mmtv) (called mtvs), which have multiple replication defects. a balb/c congenic mouse strain lacking all endogenous mtvs (mtv-null) was resistant to mmtv oral and intraperitoneal infection and tumorigenesis compared to wild-type balb/c mice. infection of mtv-null mice with an mmtv-related retrovirus, type b leukemogenic virus, also resulted in severely reduced viral loads and failure to induce t-cell lymphom ... | 2006 | 17140288 |
| a dynamic, mitotic-like mechanism for bacterial chromosome segregation. | the mechanisms that mediate chromosome segregation in bacteria are poorly understood. despite evidence of dynamic movement of chromosome regions, to date, mitotic-like mechanisms that act on the bacterial chromosome have not been demonstrated. here we provide evidence that the vibrio cholerae parai and parbi proteins are components of an apparatus that pulls the origin region of the large v. cholerae chromosome to the cell pole and anchors it there. parbi interacts with a conserved origin-proxim ... | 2006 | 17158745 |
| genetic organization of pre-ctx and ctx prophages in the genome of an environmental vibrio cholerae non-o1, non-o139 strain. | the cholera toxin (ct) is a critical determinant of the virulence of epidemic vibrio cholerae strains. the ctxab operon encoding ct is part of the genome of a filamentous bacteriophage ctxphi, which may integrate as a single copy or as multiple copies in the genome of v. cholerae. the ctxphi genome is composed of rs2 (2.4 kb) and core (4.5 kb) regions. in the present study extensive genetic mapping analyses indicated that two copies of tandemly arrayed ctx prophages are integrated in the small c ... | 2006 | 17159216 |
| [comparative characteristics of the preparations of hemolysin of ctx+ and ctx- vibrio cholerae eltor and vibrio cholerae o139 strains]. | hemolysin of ctx+ vibrio cholerae strains was obtained and studied. ctx+ vibrio cholerae o1 and o139 strains produced the hemolysin during cultivation in triptone medium without fecl3. mol.wt. and the spectrum of lytic activities of hemolysins of ctx+ vibrio cholerae did not differ from hemolysins of ctx- strains. | 2006 | 17163139 |
| [evolution of the epidemiology of cholera]. | the problems of the evolution of cholera at the stages of its pandemic spread are described. a short characterization of endemic zones in the countries of asia, africa and latin america, stipulating the preservation of infection and the appearance of periodic epidemics in the world, is presented. special attention is paid to the genesis of epidemic outbreaks in endemic and introduced foci of cholera, differing in the specific features of their formation and the accumulation of the epidemic varia ... | 2006 | 17163143 |
| [investigation on vibrio cholera carried in aquatic products of littoral areas, zhejiang province]. | to examine vibrio cholera (v.c) in aquatic products of littoral area, zhejiang province and to provide scientific evidence for administration of aquatic products and cholera epidemic control. | 2006 | 17166425 |
| the abcs (antibody, b cells, and carbohydrate epitopes) of cholera immunity: considerations for an improved vaccine. | cholera, a diarrheal disease, is known for explosive epidemics that can quickly kill thousands. endemic cholera is a seasonal torment that also has a significant mortality. not all nations with extensive rural communities can achieve the required infrastructure or behavioral changes to prevent epidemic or endemic cholera. for some communities, a single-dose cholera vaccine that protects those at risk is the most efficacious means to reduce morbidity and mortality. it is clear that our understand ... | 2006 | 17179659 |
| enteropathogenic bacteria and enterotoxin-producing staphylococcus aureus isolated from ready-to-eat foods in khon kaen, thailand. | the objective of this study was to investigate the microbiological quality of ready-to-eat food in the municipality of khon kaen, thailand. four categories of 186 food samples were collected: (1) high heat food; (2) low heat food; (3) no heat food; and, 4) on-site prepared fruit juices and beverages. of the food samples, 145 (78%) failed to meet acceptable microbiological standards, including fruit juice and beverages (100%), no heat food (91.7%), low heat food (81.7%) and high heat food (57.9%) ... | 2006 | 17333744 |
| molecular analysis of vibrio cholerae strains isolated in malaysia: public health implications. | the genetic diversity or clonality among vibrio cholerae o1, o139 and non-o1/ non-o139 of clinical and environmental origin using ribotyping and pfge was performed in order to ascertain the public health implications of the different genotypes circulating within the malaysian environment. using an in-house typing scheme, of the 214 strains included, 202 strains were isolated locally between 1992 and 1998, seven were obtained from bangladesh and five were reference strains. amongst the 176 el tor ... | 2006 | 17153080 |
| evolutionary migration of a post-translationally modified active-site residue in the proton-pumping heme-copper oxygen reductases. | in the respiratory chains of aerobic organisms, oxygen reductase members of the heme-copper superfamily couple the reduction of o2 to proton pumping, generating an electrochemical gradient. there are three distinct families of heme-copper oxygen reductases: a, b, and c types. the a- and b-type oxygen reductases have an active-site tyrosine that forms a unique cross-linked histidine-tyrosine cofactor. in the c-type oxygen reductases (also called cbb3 oxidases), an analogous active-site tyrosine h ... | 2006 | 17176062 |
| [uninary infection due to non-01, non-0139 vibrio cholerae]. | 2006 | 17203558 | |
| two unrelated cases of septicaemia due to vibrio cholerae non-o1, non-o139 in poland, july and august 2006. | 2006 | 17213560 | |
| [sequence analysis of housekeeping genes reca, dnae, and mdh in different serogroups or biotypes of vibrio cholerae isolated from china]. | to analyze sequences of the housekeeping genes including reca, dnae, and mdh in different serogroups or different biotypes of vibrio cholerae (vc) strains isolated from china. | 2006 | 17259105 |
| [classification and identification of vibrio cholerae and vibrio parahaemolyticus isolates based on gyrb gene phylogenetic analysis]. | in order to validate the usefulness of gyrb genotype for the classification and identification of vibrio cholerae and vibrio parahaemolyticus isolates, the phylogenetic analysis of 13 v. cholerae, 8 v. parahaemolyticus, 2 aeromonas hydrophila and 1 plesiomonas shigelloides strains was carried out using the partial coding sequence of gyrb, a gene that encodes the b subunit of dna gyrase (topoisomerase type ii ) in bacteria. these strains were separately clustered at species level and typed by the ... | 2006 | 17302148 |
| evaluation of phytotoxic elements, trace elements and nutrients in a standardized crop plant, irrigated with raw wastewater treated by apt and ozone. | this project studied the benefits of applying advanced primary treatment (apt) and ozone (o3) to raw wastewater destined for reuse in agriculture. the ozone was applied directly to raw wastewater, as well as to wastewater already treated with apt, and the results compared against a control sample of potable water. the experimental conditions that reported the best results was wastewater treated with o3 (at a dose of 4.8 mg/l, at ph 7, temperature 23 degrees c, for 1 hr), given that it met standa ... | 2006 | 17302317 |
| routine use of antimicrobial drugs during the 2004 cholera epidemic in douala, cameroon. | to evaluate routine use of antimicrobial drugs for treatment and prevention of cholera with special regards to the evolution of the antimicrobial drug resistance patterns of v. cholerae strains. | 2006 | 17455448 |
| detection, isolation, and identification of vibrio cholerae from the environment. | microbiological techniques for sampling the aquatic realm have become increasingly sophisticated, especially with advances in molecular biology. these techniques have been used to detect microorganisms that cannot be cultured by conventional bacteriological methods. this has resulted in a deeper and a clearer understanding of the ecology and epidemiology of microorganisms. important advances have been made in isolation, detection, and identification of vibrio cholerae over the past decade. the u ... | 2006 | 18770592 |
| issues with radiation therapy article. | 2006 | 1828682 | |
| issues with radiation therapy article. | 2006 | 1828682 | |
| bronchial rupture. | 2006 | 1865682 | |
| bronchial rupture. | 2006 | 1865682 | |
| [detection of retinal visual field defects by sectorial photic stimulation in scotopic luminance erg]. | we developed an electroretinographic procedure to assess visual field defects due to dysfunction of the outer retinal layers. for this objective we determined the amplitude/intensity function of the scotopic b-wave to full field (100 degrees of visual angle), quadrant and hemifield stimulation in 14 healthy volunteers and in patients with visual field disturbances. to prevent stray light effects, we confined the test light illuminance to 10(1.3) of the extrapolated normal erg threshold (about 10 ... | 2006 | 1855744 |
| [detection of retinal visual field defects by sectorial photic stimulation in scotopic luminance erg]. | we developed an electroretinographic procedure to assess visual field defects due to dysfunction of the outer retinal layers. for this objective we determined the amplitude/intensity function of the scotopic b-wave to full field (100 degrees of visual angle), quadrant and hemifield stimulation in 14 healthy volunteers and in patients with visual field disturbances. to prevent stray light effects, we confined the test light illuminance to 10(1.3) of the extrapolated normal erg threshold (about 10 ... | 2006 | 1855744 |
| the accuracy of confrontation visual field test in comparison with automated perimetry. | the accuracy of confrontation visual field testing was determined for 512 visual fields using automated static perimetry as the reference standard. the sensitivity of confrontation testing excluding patchy defects was 40% for detecting anterior visual field defects, 68.3% for posterior defects, and 50% for both anterior and posterior visual field defects combined. the sensitivity within each group varied depending on the type of visual field defect encountered. confrontation testing had a high s ... | 2006 | 1800764 |
| the accuracy of confrontation visual field test in comparison with automated perimetry. | the accuracy of confrontation visual field testing was determined for 512 visual fields using automated static perimetry as the reference standard. the sensitivity of confrontation testing excluding patchy defects was 40% for detecting anterior visual field defects, 68.3% for posterior defects, and 50% for both anterior and posterior visual field defects combined. the sensitivity within each group varied depending on the type of visual field defect encountered. confrontation testing had a high s ... | 2006 | 1800764 |
| diagnosis of complex acid-base disorders: physician performance versus the microcomputer. | patients with acid-base disturbances that are often complex frequently present to the emergency department. the sometimes hectic nature of the ed can preclude the appropriate quantitative analysis required by these disorders, especially when mixed disturbances are present. a computer program using generally accepted acid-base and electrolyte formulae was developed for use on the apple ii+ or ibm-pc microcomputer. each of a series of 35 acid-base disturbances incorporating single, double, and tri ... | 2006 | 3511785 |
| diagnosis of complex acid-base disorders: physician performance versus the microcomputer. | patients with acid-base disturbances that are often complex frequently present to the emergency department. the sometimes hectic nature of the ed can preclude the appropriate quantitative analysis required by these disorders, especially when mixed disturbances are present. a computer program using generally accepted acid-base and electrolyte formulae was developed for use on the apple ii+ or ibm-pc microcomputer. each of a series of 35 acid-base disturbances incorporating single, double, and tri ... | 2006 | 3511785 |
| [nailbed transplantation, a possibility for reconstruction]. | to satisfy the demands of tactile gnosis, it is necessary to have intact fingertips. for this purpose, the fingernail has an important function. with the help of an example of a nailbed transplantation after a complete amputation of a finger end, a possibility of reconstruction of injured fingertips, especially of the nailbed, is shown. attention is called to the importance of an exact primary treatment of injured nailbeds. | 2006 | 2870619 |
| [nailbed transplantation, a possibility for reconstruction]. | to satisfy the demands of tactile gnosis, it is necessary to have intact fingertips. for this purpose, the fingernail has an important function. with the help of an example of a nailbed transplantation after a complete amputation of a finger end, a possibility of reconstruction of injured fingertips, especially of the nailbed, is shown. attention is called to the importance of an exact primary treatment of injured nailbeds. | 2006 | 2870619 |
| a general software package for the handling of medical images. | pics (portable imaging computer software), is a software system designed for handling and processing a variety of types of medical image. it has been designed to satisfy the following criteria: (a) the software should be portable between different items of hardware with minimal alteration; (b) there should be a simple operator interface to enable use by inexperienced users, while avoiding the need for experienced users to be directed through tedious menu trees; (c) the programming environment sh ... | 2006 | 1800747 |
| a general software package for the handling of medical images. | pics (portable imaging computer software), is a software system designed for handling and processing a variety of types of medical image. it has been designed to satisfy the following criteria: (a) the software should be portable between different items of hardware with minimal alteration; (b) there should be a simple operator interface to enable use by inexperienced users, while avoiding the need for experienced users to be directed through tedious menu trees; (c) the programming environment sh ... | 2006 | 1800747 |
| aggressive chemotherapy for acute leukaemia frequently causes intestinal protein leakage. | cytostatic drugs are known to produce disturbances in intestinal absorption of carbohydrates. to further explore the gastrointestinal (gi) toxicity of cytostatic therapy, 37 patients with acute leukemia were investigated during and/or after remission induction courses by the use of the differential sugar absorption test (dsat) and the intestinal clearance of alpha-1-antitrypsin (claat). the ratio of the lactulose to the mannitol excretion in the urine was found abnormal in 44% of the tests. the ... | 2006 | 1828960 |
| aggressive chemotherapy for acute leukaemia frequently causes intestinal protein leakage. | cytostatic drugs are known to produce disturbances in intestinal absorption of carbohydrates. to further explore the gastrointestinal (gi) toxicity of cytostatic therapy, 37 patients with acute leukemia were investigated during and/or after remission induction courses by the use of the differential sugar absorption test (dsat) and the intestinal clearance of alpha-1-antitrypsin (claat). the ratio of the lactulose to the mannitol excretion in the urine was found abnormal in 44% of the tests. the ... | 2006 | 1828960 |
| proton and carbon chemical-shift assignments for 6-kestose and neokestose from two-dimensional n.m.r. measurements. | the proton and carbon chemical shift assignments of the simplest levan, 6-kestose, [o-beta-d-fructofuranosyl-(2----6)-beta-d-fructofuranosyl-(2 in equilibrium with 1)-alpha-d-glucopyranoside], along with another trisaccharide, neokestose, [o-beta-d-fructofuranosyl-(2----6)-alpha-d-glucopyranosyl-(1 in equilibrium with 2)-beta-d-fructofuranoside], were determined using two-dimensional (2d) homonuclear and heteronuclear n.m.r. methods. the 1h peak of h-1 of the glucose residue was determined by it ... | 2006 | 1797405 |
| proton and carbon chemical-shift assignments for 6-kestose and neokestose from two-dimensional n.m.r. measurements. | the proton and carbon chemical shift assignments of the simplest levan, 6-kestose, [o-beta-d-fructofuranosyl-(2----6)-beta-d-fructofuranosyl-(2 in equilibrium with 1)-alpha-d-glucopyranoside], along with another trisaccharide, neokestose, [o-beta-d-fructofuranosyl-(2----6)-alpha-d-glucopyranosyl-(1 in equilibrium with 2)-beta-d-fructofuranoside], were determined using two-dimensional (2d) homonuclear and heteronuclear n.m.r. methods. the 1h peak of h-1 of the glucose residue was determined by it ... | 2006 | 1797405 |
| physician execs bring clinical insight to non-clinical challenges. | many physicians look to administrative careers as a natural step in their professional development. but the training and development of a hospital manager is strikingly different from that of a clinician. physician executives who've made the transition to a variety of posts, including that of ceo, speak out on the shifts and surprises involved in making the transition. | 2006 | 1885200 |
| [costs of caries therapy and prevention in a school]. | the prevalence of dental caries in the school children population in rieti is very high, according to low levels of fluoride content in drinkable water, similar to those detected in other areas of italy and europe. the aim of our research is to propose a combined prevention protocol, utilizing fluoride tablets and dental therapy through structures already existing in the public health national organization. the application of this combined (profilaxis-therapy) protocol is expected to decrease th ... | 2006 | 2517848 |
| socioeconomic status and morbidity and mortality in hypertensive blacks. | despite an overall limited range of social and economic opportunities in the recent past, blacks of lower socioeconomic status have experienced marked excesses in hypertension-related burdens compared with their more advantaged peers: the incidence, prevalence, and severity of hypertension and its end-organ sequelae increased with decreasing educational achievement and the 5-year mortality was two times higher for black hypertensives of lower than higher educational achievement under conditions ... | 2006 | 1828391 |
| socioeconomic status and morbidity and mortality in hypertensive blacks. | despite an overall limited range of social and economic opportunities in the recent past, blacks of lower socioeconomic status have experienced marked excesses in hypertension-related burdens compared with their more advantaged peers: the incidence, prevalence, and severity of hypertension and its end-organ sequelae increased with decreasing educational achievement and the 5-year mortality was two times higher for black hypertensives of lower than higher educational achievement under conditions ... | 2006 | 1828391 |
| plant resistance mechanisms to air pollutants: rhythms in ascorbic acid production during growth under ozone stress. | relationships between ozone (o3) tolerance and leaf ascorbic acid concentrations in o3-susceptible (o3-s) 'hark' and o3-resistant (o3-r) 'hood' soybean, glycine max (l.) merr., cultivars were examined with high-performance liquid chromatography (hplc). leaf samples were analyzed at 4 intervals during a 24 h period. soybean cultivars grown in the greenhouse with charcoal filtered (cf) and nonfiltered (nf) air showed daily oscillations in ascorbic acid production. highest ascorbic acid levels in l ... | 2006 | 1797413 |
| plant resistance mechanisms to air pollutants: rhythms in ascorbic acid production during growth under ozone stress. | relationships between ozone (o3) tolerance and leaf ascorbic acid concentrations in o3-susceptible (o3-s) 'hark' and o3-resistant (o3-r) 'hood' soybean, glycine max (l.) merr., cultivars were examined with high-performance liquid chromatography (hplc). leaf samples were analyzed at 4 intervals during a 24 h period. soybean cultivars grown in the greenhouse with charcoal filtered (cf) and nonfiltered (nf) air showed daily oscillations in ascorbic acid production. highest ascorbic acid levels in l ... | 2006 | 1797413 |
| prospective, controlled, double-blind study of i.v. tenoxicam for analgesia after thoracotomy. | we have shown that a single i.v. dose of tenoxicam 20 mg, after thoracotomy, when compared with placebo in 20 patients (with one exclusion), was associated with a reduction in consumption of papaveretum, assessed by patient-controlled analgesia, of 2.2 mg h-1 (22%) to 4 h and 1.4 mg h-1 (23%) to 12 h after operation (repeated measures analysis of variance: p less than 0.01). there was no reduction from 12 to 24 h. there was no significant difference between groups in pain scores or in side effec ... | 2006 | 1637611 |
| neonatal exposure to protoporphyrin-activating lighting as a contributing cause of childhood acute lymphocytic leukemia. | while being a relatively rare disease, acute lymphocytic leukemia (all) is the leading form of cancer in children in the developed world today. all sharply peaks in incidence at ages three to four years. in the united states there have been persistent, unexplained increases in incidence of all in the past two decades. we hypothesize that exposure to photosensitizing lighting immediately after birth may be a contributing cause of all. fluorescent lamps and other light sources with strong illumina ... | 2006 | 1617127 |
| [comparative evaluation of regulated and non-regulated periods of work and rest in a high-temperature microclimate in the glass industry]. | during warm periods of the year under unregulated work regimen the thermal state of the workers of glass manufacturing hot shops was regarded as discomfort. under regulated work regimen the indices of workers' thermal state and hemodynamics were stabilized at a lower level. the dynamics of changes of the central nervous neuromuscular systems was also more favourable compared to the unregulated regimen. it was considered advisable to restrict the time of continuous stay at the workplace with heat ... | 2006 | 2526060 |
| regulation of calcium current by low-km cyclic amp phosphodiesterases in cardiac cells. | the voltage-gated ca2+ current (ica) in cardiac myocytes is regulated by camp-dependent phosphorylation. although the regulation of ica via mechanisms involving modulation of camp synthesis is well understood, the regulation of camp degradation has been less thoroughly investigated. the goal of the present study was to investigate the participation of different subclasses of camp phosphodiesterase (pde) in regulating camp-dependent phosphorylation of ca2+ channels in frog ventricular myocytes. c ... | 2006 | 1698253 |
| [excitation-contraction coupling and ion transport in membrane of skeletal muscle]. | 2006 | 1698230 | |
| the value of an expert system in performing clinical drug trials. | an expert system has been designed to assist the cardiologist in determining whether patients can be included in clinical trials. this system contains knowledge on inclusion and exclusion criteria for six drug trials, and has been validated in 100 randomly selected patients. in 97 cases, the expert system and the cardiologist made an identical classification; in the remaining three cases, the patient was incorrectly classified by the physician. the system will also optimize the order in which qu ... | 2006 | 1764928 |
| decreased monocyte-induced angiogenesis in scleroderma. | 2006 | 1698391 | |
| [a hypertensive crisis during surgery in a patient with neuroblastoma]. | neuroblastoma is the most common solid tumour in infancy and childhood. the tumour usually produces large amounts of catecholamines. few patients with neuroblastoma, however, were reported to have become hypertensive because of catecholamine metabolism within the tumour itself. this is one of the most important differences compared with pheochromocytomas. we experienced a hypertensive crisis accompanied by tachycardia and an increase in the plasma catecholamine concentration during surgery in a ... | 2006 | 1578628 |
| [treatment procedure in humeral shaft fractures with primary or secondary radial nerve damage]. | we give an account of 28 patients with fractured humerus diaphysis, suffering from primary and seven patients suffering from secondary lesion of the radialis nerve, all treated by operation. in each case the radialis nerve was exposed and the fracture was treated by fixation with compression plates. in case of primary lesions of the radialis nerve, we found intraoperative damages by traction (six times), contusions (seven times), intraneural hämatomas (six times) and for one time perforation of ... | 2006 | 1636222 |
| occupational exposure to carbon monoxide during charcoal meat grilling. | charcoal meat grill workers are one of the many occupational groups that are subject to carbon monoxide exposure. this group have often been overlooked and not investigated. carboxyhemoglobin (%cohb) levels in 100 male workers were assessed before work and after work the same day. carboxyhemoglobin levels increased significantly after work in both smoking and nonsmoking workers. the mean cohb levels for smoking workers before work was 3.8% and for nonsmokers was 2.4%, whereas after work, the mea ... | 2006 | 1594919 |
| fludarabine monophosphate for prolymphocytic leukaemia. | 2006 | 1698237 | |
| plastic ampoules. | 2006 | 1609921 | |
| unilateral akathisia. | 2006 | 2573863 | |
| [dynamics of the thumb in arthritis]. | 2006 | 1698086 | |
| [a case of ovarian sertoli-leydig cell tumor associated with high serum alpha-fetoprotein (afp) concentration]. | 2006 | 1698212 | |
| [psychoreactive disorders: clinical description of pathologic reactions, pathologic reactive states and reactive psychoses]. | after the introduction to the problem presented in the first part, the author submits a description of clinical units. the aim is to provide documentation of his concept and to unify the understanding of these conditions into a uniform system; conditions which, although adequately described, are included among different disorders and their classification and description is not uniform. the need of this description is urgent not only because the new generation of psychiatrists does not know the o ... | 2006 | 2225188 |
| acquisition, generalization, and spontaneous use of color adjectives: a comparison of incidental teaching and traditional discrete-trial procedures for children with autism. | incidental teaching and traditional discrete-trial procedures were used to teach two children with autism the expressive use of two color adjectives to describe preferred toys and food items. the two teaching procedures were performed in a classroom setting, and generalization and spontaneous usage were assessed at home with parents. the results demonstrated that traditional discrete-trial teaching was more efficient and produced faster acquisition and, initially, greater generalization. however ... | 2006 | 1626079 |
| [the visit of the soviet military medical delegation to china]. | 2006 | 2014671 | |
| etoposide and adriamycin containing combination chemotherapy (hope-bleo) for relapsed hodgkin's disease. | forty-four patients with relapsed or resistant hodgkin's disease were treated with adriamycin 40 mg m-2 i.v. on day 1, vincristine 1.4 mg m-2 i.v. on days 1 and 8, prednisolone 40 mg m-2 orally daily for 8 days, etoposide 200 mg m-2 orally daily for 4 days according to the nadir white cell count, and bleomycin 10 mg m-2 i.v. days 1 and 8 (hope-bleo). median age was 27 (range 12-71). when stage was considered according to all sites currently or previously involved by hodgkin's disease (cumulative ... | 2006 | 1695523 |
| a pathomorphological study of parathyroid tumors. | 2006 | 4469177 | |
| [poisoning at a polyvalent intensive care unit]. | a retrospective analysis was made concerning 1340 admissions to a multidisciplinary intensive care unit over four years (1986-1989), because of acute poisoning. in 666 patients occurred 735 drug overdoses and in 674 patients, 691 non-drug intoxications. the drugs with main action in central nervous system were the most frequent in drug overdoses and the organophosphates insecticides in the non-drug intoxications. during the considered period there was an absolute and relative fall in the number ... | 2006 | 1595377 |
| how accurate is a computerized surgical audit when resident medical staff collect the data? | since july 1988 all eight general surgeons at fremantle hospital have used a computer-based surgical audit and discharge system. at the time of writing (september 1991) 10,919 computer-generated discharge letters have been produced by the system. this paper describes the system and reports a series of quality control assessments carried out between 1 july 1988 and 30 june 1990 during which 30 pre-registration surgical residents completed 5,716 data collection forms. it was found that: (1) data c ... | 2006 | 1610325 |
| isolation of the right subclavian artery. | loss of continuity between subclavian artery and aorta with persistent connection to the homolateral pulmonary artery through a ductus arteriosus is an uncommon malformation, involving generally the left subclavian artery and associated with intracardiac or aortic arch anomalies. we report a case of right subclavian isolation with a left-sided aortic arch, presenting as a single anomaly and surgically corrected by aortic reimplantation. | 2006 | 1540070 |
| treatment of early rheumatoid arthritis with rifampicin. | following a report that seven of 20 patients with rheumatoid arthritis (ra) had come into clinical and laboratory remission after treatment with rifampicin, and that six of the seven responders had a disease duration of less than three years, 21 patients with classical or definite ra of recent onset were treated with 600 mg rifampicin and 300 mg isoniazid daily for six months. fourteen of 21 patients completed six months' treatment, but there was no significant improvement in the mean values of ... | 2006 | 1540033 |
| prophylaxis against non-steroidal induced upper gastrointestinal side effects. | 2006 | 1540030 |