Publications

[plasma level of ketone bodies in children with simple obesity and urinary excretion of ketone bodies. ii].		2005	1134867
letter: microvilli.		2005	1065167
arthroplasties of the upper extremity.		2005	1064951
guest editorial.		2005	1064923
the intravenous infusion of co-trimoxazole in cases of septicaemia: tolerance and results of treatment.	the tolerance to co-trimoxazole given by intravenous infusion was investigated in 25 patients suspected to be suffering from septicaemia. one patients developed allergic skin manifestations and two had increased difficulties with cardiac insufficiency, probably on account of the infusion. the other patients tolerated well. the results of treatment of 11 patients with septicaemia were good in 8 cases. in 2 cases, the poor results of the treatment can be explained by the presence of undrained absc ...	2005	1064919
control orientation among alcoholics: a cognitive social learning perspective.	a cognitive social learning model of the maintenance of problem drinking is presented. basic constructs involving social skills acquisition, experienced cognitive control and self-efficacy expectations as they relate to alcoholism are discussed. it is concluded that the model provides a useful theoretical framework in which to conceptualize the development, maintenance and treatment of drinking problems. a number of specific suggestions are made for further research which test various hypotheses ...	2005	549475
[intracellular mechanisms of cholestasis].		2005	3320466
the relationship of pretreatment family functioning to drinking behavior during follow-up by alcoholic patients.	the relationship of alcoholics' perceptions of the pretreatment functioning of their families to drinking outcomes during an 18-month follow-up was examined. family functioning was hypothesized to be predictive of drinking behavior, particularly in subjects with low assertion of autonomy scores. these individuals report greater dependency and attachment, and therefore might be more affected by the state of important relationships. the results indicated that with low autonomy male alcoholics, gre ...	2005	1449124
mandibular growth and dysfunction: a cephalometric and electromyographic analysis of a cross-bite case.		2005	1065355
[functional and radiological aspects of the coronary venous phase].		2005	548099
management of acute manifestations of filariasis.		2005	546989
electrocardiographic changes under moderate hypoxia.		2005	546723
[impedance cardiographic studies of the athlete's heart].		2005	545698
[comparative study of the effectiveness of verapamil and propranolol in unstable angina].		2005	549626
[electronmicroscopic observation on acinic cell tumors of the parotid gland].	under the electronmicroscope we observed a case of an acinic cell tumor of the left parotid gland. the patient was a 63-year-old woman who has suffered three times from local recurrences. the cytoplasma of the tumor cells showed the well-organized mitochondria, rouch endoplasmic reticula, golgi's complexes and other organellas. especially the cytoplasmas of the tumor cells, which formed acinus-like lumens, contained various-shaped secretory granules in great numbers. in addition, pycnotic-nuclea ...	2005	549562
overcoming early cyclosporine nephrotoxicity after liver transplantation.		2005	2652724
dupuytren's contracture and gouty tophi in a black patient.	dupuytren's disease is a relatively rare occurrence in a patient of the black race. the coexistence of a dupuytren's contracture in a black patient who also presents with severe gouty tophi is described. this is the first reported case in the english literature.	2005	1994071
[rediscovered food allergy].		2005	544238
fibrous papule of the face. a study of five cases by electron microscopy.	the stellate-shaped and multinucleated cells in fibrous papule of the face from five patients were studied by electron microscopy and found to be fibrohistiocytic cells.	2005	543528
neuroendocrine effects of apomorphine: characterization of response patterns and application to schizophrenia research.	apomorphine, a direct-acting dopamine agonist, stimulates release of growth hormone (hgh) and suppresses release of prolactin (prl) from the anterior pituitary. previous studies comparing the magnitude of these responses in schizophrenics and controls suggest that many acute (and some chronic) schizophrenics have exaggerated hgh responses; many chronic schizophrenics (and patients with tardive dyskinesia) have blunted hgh responses to apomorphine, and possibly blunted prl responses. the present ...	2005	540209
[rehabilitation after myocardial infarct and heart surgery in the aged].		2005	538947
[congenital cutis marmorata teleangiectatica].		2005	538838
the cardiovascular effects of vecuronium during halothane anaesthesia.	in a double-blind, placebo-controlled, prospective randomized trial in 70 otherwise healthy patients undergoing elective surgery of the thyroid gland, the breast, the inguinal canal or the lower limbs, we studied the cardiovascular effects of vecuronium during halothane-nitrous oxide anaesthesia. vecuronium was found to have no clinically significant influence on heart rate or mean arterial pressure, before or during surgery. bradycardia was a rare event under the special conditions of the study ...	2005	2572136
[rett's syndrome: description of a case with abnormal respiratory pattern].	rett' syndrome is a progressive disorder that occurs in females and is characterized by autistic behavior, dementia, ataxia, loss of purposeful use of the hands, and seizures. patients with rett' syndrome have been observed to have stereotyped hand movements (hand-washing) and to exhibit intermittent hyperventilation. to characterize more precisely the respiratory pattern associated with this disorder, sao2 and ph studies were made during sleep and wakefulness in a girl with this syndrome. these ...	2005	1298942
[rett's syndrome: description of a case with abnormal respiratory pattern].	rett' syndrome is a progressive disorder that occurs in females and is characterized by autistic behavior, dementia, ataxia, loss of purposeful use of the hands, and seizures. patients with rett' syndrome have been observed to have stereotyped hand movements (hand-washing) and to exhibit intermittent hyperventilation. to characterize more precisely the respiratory pattern associated with this disorder, sao2 and ph studies were made during sleep and wakefulness in a girl with this syndrome. these ...	2005	1298942
hangman's fracture in head injury.	five patients with fracture of pedicle of axis vertebra as a complication of head injury are reported. the ages of the patients ranged from 16-25 years and all of them were victims of road traffic accidents. the head injuries were moderately severe requiring admission. the average glasgow coma scale sum on admission was 11. simple non-operative management in a well padded stiff collar with sand bags supporting the head in a neutral position in bed resulted in full recovery without complication a ...	2005	2606051
[a chemical necrosis].		2005	1308898
unilateral tubal quadruplet pregnancy. a case report.	a woman had a unilateral tubal quadruplet pregnancy. this is believed to be the second published report of such an extremely rare occurrence.	2005	3367346
lamellar macular hole: a complication of cystoid macular edema after cataract extraction: a clinicopathologic case report.		2005	1246806
[editorial: pain in the upper abdomen].		2005	1251497
studies on the tube building amphipod corophium triaenonyx stebbing from visakhapatnam harbour. seasonal distribution.		2005	1230989
[repair of voluminous laparoceles].		2005	1226240
a concise parametric representation of electrocardiograms.		2005	1193621
[surgical treatment of pulmonary embolism in obstetrical-gynecological practice].		2005	1200312
movement aftereffects contingent on the colour or pattern of a stationary surround.		2005	1198934
detection of haemophilia carriers.		2005	1201252
neuropsychological deficits in 'primary' and 'secondary' non-medical drug users.	an extensive neuropsychological test battery, specifically designed to investigate brain-behaviour relationships, was administered to two groups of multiple drug users. the 'primary' group consisted of subjects referred fundamentally on account of drug abuse problems. the 'secondary' group were referred principally for neurological reasons, but during history taking they reported drug use. fifty patients, in all, were examined. results showed that people who have received psychiatric care for dr ...	2005	1182648
letter: si units or sd units or both?		2005	1182619
13-cis retinoic acid enhances in vivo b-lymphocyte differentiation in patients with common variable immunodeficiency.	retinoic acid (ra) has been demonstrated to drive both phenotypic and functional in vitro differentiation of b cell hybridomas from patients with common variable immunodeficiency (cvi) who manifest an "intrinsic" defect in terminal b cell differentiation (j exp med 1988;168: 55-71). therefore, we conducted an open trial to determine the effects of oral 13-cis ra (0.5 mg/kg/day; 12 weeks receiving and 12 weeks without drug) on in vivo b cell differentiation in subjects with cvi. at various times ...	2005	1720149
scope of ophthalmic plastic and reconstructive surgery.		2005	1177928
sonography and computed tomography of a gossypiboma and in vitro studies of sponges by ultrasound. case report.	a case of retained surgical sponge was imaged by ultrasound and computed tomography (ct). sonography revealed a hypoechoic mass with areas of high echoes and acoustic shadowing. an experiment revealed that the high echoes were attributed partly to the presence of numerous interfaces of sponges. the sonographic detection of a mass with high echoes casting acoustic shadows should alert radiologists to the possibility of retained surgical sponges even if there is no gas or calcification on ct scans ...	2005	1473032
recent life changes and the reporting of psychological states.		2005	1142319
isolation and purification of amyloid protein a by sodium dodecyl sulphate polyacrylamide gel electrophoresis and reversed-phase high-performance liquid chromatography.	sodium dodecyl sulphate polyacrylamide gel electrophoresis and reversed-phase high-performance liquid chromatography (hplc) were used consecutively for the isolation of amyloid protein a (protein aa) from amyloid fibrils. highly purified protein aa was obtained and determined by electrophoretic and amino acid analyses. the heterogeneity of protein aa was shown by hplc. the isoforms of protein aa had different hydrophobicities, although they were equal in size and similar in amino acid compositio ...	2005	1564099
echographic assessment of atrial transport, mitral movement, and ventricular performance following electroversion of supraventricular arrhythmias.	controversy attends the extent and temporal sequence of improvements in hemodynamic function resulting from the return of atrial contraction following cardioversion of supraventricular arrhythmias. thus, mitral, left atrial (la) and left ventricular (lv) echograms were obtained before and one hour after conversion of supraventricular arrhythmias to normal sinus rhythm by direct current countershock in patients with chronic coronary disease or cardiomyopathies without valvular dysfunction. the du ...	2005	1112007
percutaneous stimulation in the treatment of acute and chronic pain.		2005	1087340
george william gower, 1887-1974.		2005	1090621
lack of haemodialysis-associated amyloidosis.		2005	1681397
intracellular defect of neutrophils in patients with cancer.		2005	552829
collagen heterogeneity of skin.		2005	549484
congenital cyanotic heart disease with "situs solitus", dextroversion, juxtaposition of the atrial appendages and anatomical malposition of the great arteries. report of a case with surgical correction.		2005	549464
mothers' comprehension of terminology associated with the care of a newborn baby.	to determine mothers' level of comprehension of terminology used by health care providers when discussing the care of a newborn baby. sixty patients on a postpartum unit in a general hospital who gave birth to healthy newborns were asked to define 56 terms related to the care of newborn babies that were commonly used by health care providers. mothers' knowledge of terms was examined by level of education, number of children, previous experience caring for newborns, and age. analyses of variance ...	2005	1852507
[chronic meningococcemia--a rare prolonged infection and disturbance in the function of complement].		2005	1364465
an ophthalmic study of ibuprofen in rheumatoid conditions.	a total of 247 patients suffering from rheumatoid arthritis and allied conditions were referred for routine ophthalmological examination with particular reference to ocular rheumatoid involvement. of these, 197 were already receiving ibuprofen before their first assessment while 50 had a baseline assessment before commencement of ibrupofen therapy. all patients were examined on at least two occasions. no macular lesions were discovered which could be directly attributed to ibuprofen therapy.	2005	1277880
[television and the physical health of the child].		2005	547895
mental illness.		2005	547864
solitary neurofibroma of the maxilla: report of a case.		2005	3294358
[reticulum cell sarcoma in the eye and central nervous system masquerading as uveitis: report of a case].		2005	3294342
proceedings: wilson-mikity syndrome.		2005	1200695
sequential analysis of urinary antigen(s) in patients with sarcoma.		2005	538579
[intestinal involvement in the sea-blue histiocyte syndrome (author's transl)].		2005	538552
[the detection of a case of scleroderma during pre-prosthetic dental examination].		2005	1065241
new heparin-like insoluble materials: part ii.		2005	549503
proceedings: the transient effect of atp on k movement in hela cells.		2005	1151801
[pheochromocytoma and pregnancy (3 cases)].	in this paper, a review of pregnancy and pheocromocytoma is shown. the importance of early diagnostic and adequate management is essential in this patients. when this associations exists the management must be very carefully considered to avoid high mortality risks for both, fetus and mother. 56 cases of pheocromocytoma were studied at the instituto nacional de cardiología, three of them were pregnant women which are described in this work.	2005	549523
[certain problems of clinical course and surgical treatment of otosclerosis].		2005	1231125
increase in "null" cells in acute lymphocytic leukemia in remission on long-term immunotherapy.	in an attempt to elucidate a possible mode of action of immunotherapy in all, we studied the mononuclear subpopulation in a group of patients with all in remission on long-term immunotherapy, a similar group on chemotherapy, and a group of normal individuals. comparison of the three groups demonstrated a significant increase in the number and percentage of "null" cells in the immunotherapy group relative to the two others. although the nature of these cells is unknown, circulating stem cells, "k ...	2005	1087444
the escherichia coli hemolysin.	the escherichia coli hemolysin, earlier referred to as the hemolysin, is the best-characterized repeats in toxin (rtx) secreted by a type i exoprotein secretion system. the e. coli hemolysin is a significant virulence factor in murine models of peritonitis and ascending urinary tract infection, which suggests it is likely to be an important cytotoxin in human, extraintestinal e. coli diseases. among e. coli or salmonella strains there are no known examples of strict rtx leukotoxins in which lyti ...	2005	26443504
lipopolysaccharides of vibrio cholerae: iii. biological functions.	this review presents the salient features of the biological functions including the (i) endotoxic activities, (ii) antigenic properties, (iii) immunological responses to and (iv) phage receptor activities of the vibrio cholerae lipopolysaccharides (lps). the biological functions of the capsular polysaccharide (cps) of v. cholerae have also been discussed briefly as a relevant topic. the roles of lps and other extracellular polysaccharides in the (i) intestinal adherence and virulence of the vibr ...	2006	16185850
white shrimp (litopenaeus vannamei) recombinant lysozyme has antibacterial activity against gram negative bacteria: vibrio alginolyticus, vibrio parahemolyticus and vibrio cholerae.	c-type lysozyme has been described as an antibacterial component of the shrimp innate defence system. we determined quantitatively the antibacterial activity of white shrimp (litopenaeus vannamei) recombinant lysozyme against three gram negative bacteria: vibrio alginolyticus, vibrio parahemolyticus and vibrio cholerae, using a turbidimetric assay with live bacteria and differential bacterial viable count after interaction with the protein. in conclusion, the antibacterial activity of recombinan ...	2006	16098764
multiplex real-time pcr detection of vibrio cholerae.	cholera is an important enteric disease, which is endemic to different regions of the world and has historically been the cause of severe pandemics. vibrio cholerae is a natural inhabitant of the aquatic environment and the toxigenic strains are causative agents of potentially life-threatening diarrhoea. a multiplex, real-time detection assay was developed targeting four genes characteristic of potentially toxigenic strains of v. cholerae, encoding: repeat in toxin (rtxa), extracellular secretor ...	2006	16153727
incidence of class 1 integrons in multiple antibiotic-resistant gram-negative copiotrophic bacteria from the river torsa in india.	the presence of class 1 integrons in multiple-antibiotic-resistant (mar) gram-negative copiotrophic bacteria from the river torsa in india was detected using a polymerase chain reaction (pcr)-based screening method. among 100 isolates that were resistant to at least five of the twelve antibiotics tested, 40 carried class 1 integrons, with inserted dna regions of 0.7-3.2 kb. carriage of integrons in strains of higher mar index was found to be statistically significant. dna sequencing was used to ...	2006	16239097
conserved role of the linker alpha-helix of the bacterial disulfide isomerase dsbc in the avoidance of misoxidation by dsbb.	in the bacterial periplasm the co-existence of a catalyst of disulfide bond formation (dsba) that is maintained in an oxidized state and of a reduced enzyme that catalyzes the rearrangement of mispaired cysteine residues (dsbc) is important for the folding of proteins containing multiple disulfide bonds. the kinetic partitioning of the dsba/dsbb and dsbc/dsbd pathways partly depends on the ability of dsbb to oxidize dsba at rates >1000 times greater than dsbc. we show that the resistance of dsbc ...	2006	16280324
characterization of the ectoine biosynthesis genes of haloalkalotolerant obligate methanotroph "methylomicrobium alcaliphilum 20z".	the genes involved in biosynthesis of the major compatible solute ectoine (1,4,5,6-tetrahydro-2-methylpyrimidine carboxylic acid) in halotolerant obligate methanotroph "methylomicrobium alcaliphilum 20z" were studied. the complete nucleotide sequences of the structural genes encoding l: -aspartokinase (ask), l-2,4-diaminobutyric acid transaminase (ectb), l-2,4-diaminobutyric acid acetyltransferase (ecta), and l-ectoine synthase (ectc) were defined and shown to be transcribed as a single operon e ...	2006	16283251
sialylation regulates peripheral tolerance in cd4+ t cells.	decreased binding by the 6c10 auto-antibody serves as a unique marker for cd4+ t cell unresponsiveness after the induction of t cell tolerance in vbeta8.1 tcr transgenic mice. we further define the nature of the epitope recognized by the 6c10 antibody to be a subset of thy-1 bearing incompletely sialylated n-linked glycans, and furthermore, we demonstrate that tolerant cd4+ t cells have an increased degree of cell-surface sialylation. to test the significance of the altered glycosylation state i ...	2006	16291658
antimicrobial potentiality of the thioxanthene flupenthixol through extensive in vitro and in vivo experiments.	the antipsychotic thioxanthene flupenthixol, possessing a trifluoromethyl substituent at position 2, exhibited a distinct antibacterial property against 352 strains of bacteria from 3 gram-positive and 13 gram-negative genera. the minimum inhibitory concentration (mic) of flupenthixol was determined by the national committee for clinical laboratory standards agar dilution method. mics ranged from 10-100 microg/ml in most of the strains, whilst some strains were inhibited at even lower concentrat ...	2006	16316745
hyperinfectivity: a critical element in the ability of v. cholerae to cause epidemics?	cholera is an ancient disease that continues to cause epidemic and pandemic disease despite ongoing efforts to limit its spread. mathematical models provide one means of assessing the utility of various proposed interventions. however, cholera models that have been developed to date have had limitations, suggesting that there are basic elements of cholera transmission that we still do not understand.	2006	16318414
modelling, synthesis and biological evaluation of novel glucuronide-based probes of vibrio cholerae sialidase.	the development of sialidase inhibitors is an area of continuing interest due to their potential use as therapeutic agents to combat viral and bacterial infections. herein, we report our studies involving the sialidase from the pathogen vibrio cholerae, through the modelling, synthesis and biological evaluation of mimetics of 5-acetamido-2,6-anhydro-3,5-dideoxy-d-glycero-d-galacto-non-2-enonic acid (neu5ac2en, 1), a naturally occurring sialidase inhibitor. these mimetics are o- and s-glycosides ...	2006	16275104
chemotaxis between vibrio cholerae o1 and a blue-green alga, anabaena sp.	the chemotactic response of vibrio cholerae o1 towards the mucilaginous sheath of anabaena sp. was investigated by capillary tube method using a virulent strain of v. cholerae o1, el tor, ogawa (3083-t) and its isogenic mutant (hap-1-t) that lacks the hap gene, which codes for mucinase (ha/protease). homogenates of anabaena sp. and purified mucin were used in this study as chemoattractants. results showed 5.7% bacterial accumulation of wild-type v. cholerae o1 towards 4% homogenates of anabaena ...	2006	16207388
construction and evaluation of a o139 vibrio cholerae vaccine candidate based on a hema gene mutation.	in this paper, we describe the development of vcusm2, a live metabolic auxotroph of vibrio cholerae o139. auxotrophy was achieved by mutating a house keeping gene, hema, that encodes for glutamyl-trna reductase, an important enzyme in the c5 pathway for delta-aminolevulenic acid (ala) biosynthesis, which renders this strain dependent on exogenous ala for survival. experiments using the infant mouse and adult rabbit models show that vcusm2 is a good colonizer of the small intestine and elicits gr ...	2006	16102875
process development for a cuban cholera vaccine based on the attenuated strain vibrio cholerae 638.	genetically modified vibrio cholerae strain 638 (biotype el tor, serotype ogawa) has previously been shown to be immunogenic in animal models and in human trials. our objective in the work reported herein was to describe the process development methods for the production of the 638 attenuated cholera vaccine. cell seed bank, culture of biomass, lyophilization and final formulation were processes were developed. the results show kinetics of culture that fulfils a logistical model. the microbiolog ...	2006	16085342
determination of endotoxin by the measurement of the acetylated methyl glycoside derivative of kdo with gas-liquid chromatography-mass spectrometry.	a gas-liquid chromatographic-mass spectrometric (glc-ms) method was applied to the detection of 3-deoxy-d-manno-2-octulosonic acid (kdo), a constituent of bacterial lipopolysaccharide (lps, endotoxin). samples containing lps were dried, methanolyzed with 2 m hcl in methanol at 60 degrees c for 1 h and acetylated with acetic anhydride and pyridine (1:1, v/v) solution at 100 degrees c for 30 min, then the products were analyzed by glc-ms or glc-msms. four acetylated methylglycoside methyl ester de ...	2006	15932775
trophic regulation of vibrio cholerae in coastal marine waters.	cholera disease, caused by the bacterium vibrio cholerae, afflicts hundreds of thousands worldwide each year. endemic to aquatic environments, v. cholerae's proliferation and dynamics in marine systems are not well understood. here, we show that under a variety of coastal seawater conditions v. cholerae remained primarily in a free-living state as opposed to attaching to particles. growth rates of free-living v. cholerae (micro: 0.6-2.9 day(-1)) were high (similar to reported values for the bact ...	2006	16343318
resistance of the cholera vaccine candidate iem108 against ctxphi infection.	the cholera toxin (ct) genes ctxab are carried on a lysogenic phage of vibrio cholerae, ctxphi, which can transfer ctxab between toxigenic and nontoxigenic strains of bacteria. this transfer may pose a problem when live oral cholera vaccine is given to people in epidemic areas, because the toxin genes can be reacquired by the vaccine strains. to address this problem, we have constructed a live vaccine candidate, iem108, which carries an el tor-derived rstr gene. this gene encodes a repressor and ...	2006	16343705
immunosensor for the detection of vibrio cholerae o1 using surface plasmon resonance.	an immunosensor for the detection of vibrio cholerae o1 was developed on the basis of surface plasmon resonance (spr). a protein g layer was fabricated by means of the chemical coupling between the free amine (-nh2) groups of protein g and the activated carboxyl groups present on a self-assembled monolayer (sam) consisting of a mixture of 11-mercaptoundecanoic acid (mua) and hexanethiol (molar ratio of 1:2). a monoclonal antibody, which was confirmed to be specific to v. cholera o1 by the wester ...	2006	16326089
the regulatory roles of cell surface sialylation and n-glycans in human b cell lymphoma cell adhesion to galectin-1.	surface sialylation and glycosylation of tumor cells is known to affect various biological phenomena. in the present study, we analyzed the regulatory roles of cell surface sialylation in cell adhesion to galectin-1 in the human diffuse large b cell lymphoma (dlbcl) cell line, hbl-2, and burkitt's lymphoma cell line, hbl-8. vibrio cholerae neuraminidase treatment enhanced hbl-2 cell adhesion to galectin-1, suggesting that sialic acid inhibits hbl-2 cell adhesion to galectin-1. the data from empl ...	2006	16327992
a molecular model of the vibrio cholerae cytolysin transmembrane pore.	the cytotoxic activity of some of the most pathogenic strains of vibrio cholerae is associated with a cytolysin protein (vcc), which forms oligomeric transmembrane pores and changes the permeability of intestinal cells. we present here a model structure of the transmembrane pore of vcc based on sequence comparison with other pore-forming toxins. vcc is suggested to form a transmembrane beta-barrel pore with a relatively large trans vestibule region. calculations of the electrostatic profile with ...	2006	16330061
bile acids stimulate biofilm formation in vibrio cholerae.	vibrio cholerae is a gram-negative bacterium that causes the acute diarrhoeal disease cholera. after the bacterium is ingested, it passes through the digestive tract, encountering various environmental stresses including the acidic milieu of the stomach and the toxic effects of bile in the duodenum. while these stresses serve as part of a host defence system, v. cholerae has evolved resistance mechanisms that allow it to evade these defences and establish infection. we examined the expression pr ...	2006	16359328
territorial waters of the baltic sea as a source of infections caused by vibrio cholerae non-o1, non-o139: report of 3 hospitalized cases.	a fatal infection with temporal relation to 2 other febrile infections caused by vibrio cholerae non-o1, non-o139 (ncv) occurred in finland in 2003. all infections were associated with contact with seawater. the patient who died had also eaten home-salted whitefish, tested positive for ncv, preceding his symptoms. all patients had compromising factors, and all strains were distinguishable by pulsed-field gel electrophoresis and negative for the ctx gene. these 3 cases illustrate that, despite be ...	2006	16368474
identification of a constitutively active variant of luxo that affects production of ha/protease and biofilm development in a non-o1, non-o139 vibrio cholerae o110.	pathogenesis of vibrio cholerae depends on the concerted action of numerous virulence factors that includes a secreted hemagglutinin (ha) protease. recent studies have evidenced that the expression of these virulence factors as well as the genes responsible for biofilm development is subject to control by quorum sensing in this organism. at low cell density, luxo, the pivotal regulator of quorum-sensing circuit, has been shown to be phosphorylated at aspartate-47. working in concert with sigma-5 ...	2006	16376028
helicobacter pylori-associated chronic atrophic gastritis involving the gastric body and severe disease by vibrio cholerae.	evidence has associated chronic infection by helicobacter pylori with chronic gastritis, low gastric acid production and an increased risk of life-threatening cholera. however, the relationship of specific patterns of histological damage in the gastric mucosa associated with h. pylori infection and the occurrence of cholera has not been described. the purpose of this study was to compare the gastric ph and histopathological findings in gastric biopsies taken from patients with severe diarrhoeal ...	2006	16376396
recent progress in vaccines for amebiasis.	the persistence of amebiasis as a global health problem, despite the availability of effective treatment, has led to the search for vaccines to prevent this deadly disease. recent clinical studies suggest that mucosal immunity could provide some protection against recurrent intestinal infection with e. histolytica, but there is contradictory evidence about protective immunity after amebic liver abscess. progress in vaccine development has been facilitated by new animal models that allow better t ...	2006	16380333
autorepression of rctb, an initiator of vibrio cholerae chromosome ii replication.	the rctb protein binds to the origin of replication of vibrio cholerae chromosome ii (chrii) and is required for oriciivc-based replication. here, we found that rctb acts as an autorepressor, inhibiting rctb transcription. integration host factor promotes rctb transcription, while dam and dnaa, factors required for replication of both v. cholerae chromosomes, influence rctb autorepression. thus, rctb appears to regulate chrii replication as both an initiator and a transcription repressor, and it ...	2006	16385068
a vibrio cholerae relaxed (rela) mutant expresses major virulence factors, exhibits biofilm formation and motility, and colonizes the suckling mouse intestine.	we have constructed a relaxed mutant of el tor biotype vibrio cholerae strain c7258 by disruption of the rela catalytic domain. the ability of the v. cholerae relaxed mutant to biosynthesize guanosine tetraphosphate and pentaphosphate was severely affected; the mutant showed a reduced growth rate in minimal medium that could be reversed by the addition of casamino acids, and it was thermosensitive. contrary to published findings, the new rela mutant still produced significant cholera toxin and t ...	2006	16385069
fluoroquinolone-resistant vibrio cholerae isolated during a cholera outbreak in india.	during the cholera epidemic of 2002 in and around hubli, south india, vibrio cholerae strains resistant to fluoroquinolones were isolated. among the isolates of v. cholerae non-o1, non-o139 serogroups, 55.9% and 47.1% were resistant to norfloxacin and ciprofloxacin, respectively. however, only 12.5% of the o1 serogroup strains were resistant to both norfloxacin and ciprofloxacin. though the o139 serogroup strains were susceptible to these antibiotics, they exhibited multidrug resistance. emergen ...	2006	16246383
slyd proteins from different species exhibit high prolyl isomerase and chaperone activities.	slyd is a putative folding helper protein from the escherichia coli cytosol, which consists of an n-terminal prolyl isomerase domain of the fkbp type and a presumably unstructured c-terminal tail. we produced truncated versions without this tail (slyd) for slyd from e. coli, as well as for the slyd orthologues from yersinia pestis, treponema pallidum, pasteurella multocida, and vibrio cholerae. they are monomeric in solution and unfold reversibly. all slyd variants catalyze the proline-limited r ...	2006	16388577
antidiarrhoeal evaluation of aegle marmelos (correa) linn. root extract.	a study was undertaken to evaluate the in vitro and in vivo antidiarrhoeal potential of chloroform extract of the root of aegle marmelos (correa) linn. the in vitro activity was determined by agar dilution and disc diffusion techniques. the extract was studied in vivo in rats. of the 35 tested pathogenic diarrhoea causing strains, the extract was found to be mostly active against the strains of vibrio cholerae, followed by escherichia coli and shigella spp. the in vitro activity was found to be ...	2006	16397850
evaluation of three rapid diagnostic tests for cholera: does the skill level of the technician matter?	to evaluate smart, medicos dip stick and an institut pasteur (ip) cholera dipstick tests for accuracy and ease of use.	2006	16398755
comparison of methods for recovering vibrio cholerae o1 from ice.	alkaline peptone water (1% peptone, 1% nacl, ph 8.5) and trypticase soy yeast extract broth (tsyb) supplemented with 2.5% nacl (ph 8.5) or 1% nacl (ph 7.5) were evaluated as enrichment broths for the isolation of vibrio cholerae o1 from ice. thirty samples of sterile and nonsterile mineral water were inoculated with cell suspensions of this bacterium, quickly frozen, and stored for 3 days at--18 degrees c. after thawing, samples were analyzed by a three-tube most-probable-number technique. incub ...	2006	16416923
dependent population dynamics between chironomids (nonbiting midges) and vibrio cholerae.	vibrio cholerae, the causative agent of cholera, is a natural inhabitant of the aquatic ecosystem. chironomid (nonbiting midges) egg masses were recently found to harbour v. cholerae non-o1 and non-o139, providing a natural reservoir for the cholera bacterium. chironomid populations and the presence of v. cholerae in chironomid egg masses were monitored. all v. cholerae isolates were able to degrade chironomid egg masses. the following virulence associated genes were detected in the bacterial is ...	2006	16420618
disarming pathogens--a new approach for antibiotic development.		2006	16421373