Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| mosquitocidal activity of a naturally occurring isochroman and synthetic analogs from the plant pathogenic fungus, diaporthe eres against aedes aegypti (diptera: culicidae). | the culture filtrate of a plant pathogenic fungus that infects english ivy (hedera helix l., araliaceae) was investigated for mosquitocidal constituents by bioassay-guided isolation. the fungus responsible for pathogenic effects on the plant h. helix has been identified as diaporthe eres nitschke by molecular techniques. the mosquito adulticidal constituent in the culture filtrate was identified as 3,4-dihydro-8-hydroxy-3,5-dimethylisocoumarin (1) by spectroscopic techniques. laboratory bioassay ... | 2018 | 29474636 |
| comparative analysis of major mosquito vectors response to seed-derived essential oil and seed pod-derived extract from acacia nilotica. | botanical metabolites are increasingly realized as potential replacements to chemical insecticides. in the present study, acacia nilotica seed essential oil and seed pod solvent extracts were tested for bioefficacy against three important types of mosquitoes. mortality was recorded 24 h post-treatment, while smoke toxicity of adult mosquitoes was recorded at 10 min intervals for 40 min. seed pod powder was extracted with different solvents and hydrodistilled seed oil chemical constituents were d ... | 2018 | 29473901 |
| socioeconomic and human behavioral factors associated with aedes aegypti (diptera: culicidae) immature habitat in tucson, az. | aedes aegypti (l.; diptera: culicidae) has been established in the southwestern united states for several decades, but relationships between humans and mosquitoes in this arid region are not well-characterized. in august 2012, the outdoor premises of 355 houses within 20 neighborhoods in tucson, arizona were surveyed for containers that could provide larval habitat for ae. aegypti mosquitoes. at the same time, a knowledge, attitudes and practices (kap) questionnaire was administered to a residen ... | 2018 | 29471405 |
| the effect of nonrandom mating on wolbachia dynamics: implications for population replacement and sterile releases in aedes mosquitoes. | wolbachia bacteria are known to cause deviations from random mating and affect sperm competition (sc) in some of their arthropod hosts. because these effects could influence the effectiveness of wolbachia in mosquito population replacement and suppression programs, we developed a theoretical framework to investigate them and we collected relevant data for the wmel infection in aedes aegypti. using incompatibility patterns as a measure of mating success of infected versus uninfected mosquitoes, w ... | 2018 | 29968550 |
| strain-specific pathogenicity and subversion of phenoloxidase activity in the mosquito aedes aegypti by members of the fungal entomopathogenic genus isaria. | development of alternative vector control strategies are becoming more pressing given the rapid evolution of insecticide resistance and the rise of vector borne pathogens affecting public health such as dengue, chikungunya and zika. fungal-based biopesticides are promising alternatives to synthetic insecticides because they are ecofriendly and are highly effective at infecting insects through contact. this study evaluated the susceptibility of the yellow fever mosquito ae. aegypti to a range of ... | 2018 | 29967469 |
| continued susceptibility of the wmel wolbachia infection in aedes aegypti to heat stress following field deployment and selection. | aedes aegypti mosquitoes infected with the wmel strain of wolbachia are being deployed to control the spread of arboviruses around the world through blockage of viral transmission. blockage by wolbachia in some scenarios may be affected by the susceptibility of wmel to cyclical heat stress during mosquito larval development. we therefore evaluated the potential to generate a heat-resistant strain of wmel in ae. aegypti through artificial laboratory selection and through exposure to field tempera ... | 2018 | 29966368 |
| variation in competence for zikv transmission by aedes aegypti and aedes albopictus in mexico. | zikv is a new addition to the arboviruses circulating in the new world, with more than 1 million cases since its introduction in 2015. a growing number of studies have reported vector competence (vc) of aedes mosquitoes from several areas of the world for zikv transmission. some studies have used new world mosquitoes from disparate regions and concluded that these have a variable but relatively low competence for the asian lineage of zikv. | 2018 | 29965958 |
| chikungunya in children: a clinical review. | chikungunya (chikv) is an emerging arboviral infection with recent spikes in transmission in the americas. chikungunya is most commonly transmitted by mosquitos, specifically aedes aegypti and aedes albopictus. these mosquitoes are found throughout many parts of the united states. the classic tetrad of symptoms for chikv is fever, symmetric polyarthralgia, maculopapular rash, and nonpurulent conjunctivitis. although the majority (3 of 4) of infected people will be symptomatic, the viral illness ... | 2018 | 29965819 |
| adventitious viruses persistently infect three commonly used mosquito cell lines. | mosquito cell lines have been used extensively in research to isolate and propagate arthropod-borne viruses and understand virus-vector interactions. despite their utility as an in vitro tool, these cell lines are poorly defined and may harbor insect-specific viruses. accordingly, we screened four commonly-used mosquito cell lines, c6/36 and u4.4 cells from aedes albopictus, aag2 cells from aedes aegypti, and hsu cells from culex quinquefasciatus, for the presence of adventitious (i.e. exogenous ... | 2018 | 29957338 |
| patterns of occurrence of dengue and chikungunya, and spatial distribution of mosquito vector aedes albopictus in swabi district, pakistan. | two principal vector species, aedes aegypti and aedes albopictus, are known for transmission of dengue (den) and chikungunya (chk) in pakistan. we aimed to investigate their spatial and temporal distribution. | 2018 | 29956428 |
| empirical optimization of risk thresholds for dengue: an approach towards entomological management of aedes mosquitoes based on larval indices in the kandy district of sri lanka. | larval indices such as premise index (pi), breteau index (bi) and container index (ci) are widely used to interpret the density of dengue vectors in surveillance programmes. these indices may be useful for forecasting disease outbreaks in an area. however, use of the values of these indices as alarm signals is rarely considered in control programmes. therefore, the current study aims to propose threshold values for vector indices based on an empirical modeling approach for the kandy district of ... | 2018 | 29954443 |
| comparison of chikungunya viruses generated using infectious clone or the infectious subgenomic amplicons (isa) method in aedes mosquitoes. | reverse genetics systems provide the opportunity to manipulate viral genomes and have been widely used to study rna viruses and to develop new antiviral compounds and vaccine strategies. the recently described method called isa (infectious subgenomic amplicons) gives the possibility to rescue rna viruses in days. we demonstrated in cell culture that the use of the isa method led to a higher genetic diversity of viral populations than that observed using infectious clone technology. however, no r ... | 2018 | 29953474 |
| aedes anphevirus: an insect-specific virus distributed worldwide in aedes aegypti mosquitoes that has complex interplays with wolbachia and dengue virus infection in cells. | insect-specific viruses (isvs) of the yellow fever mosquito aedes aegypti have been demonstrated to modulate transmission of arboviruses such as dengue virus (denv) and west nile virus by the mosquito. the diversity and composition of the virome of a. aegypti, however, remains poorly understood. in this study, we characterized aedes anphevirus (aeav), a negative-sense rna virus from the order mononegavirales aeav identified from aedes cell lines was infectious to both a. aegypti and aedes albopi ... | 2018 | 29950416 |
| arthropod evs mediate dengue virus transmission through interaction with a tetraspanin domain containing glycoprotein tsp29fb. | dengue virus (denv) is a mosquito-borne flavivirus that causes dengue fever in humans, worldwide. using in vitro cell lines derived from aedes albopictus and aedes aegypti, the primary vectors of denv, we report that denv2/denv3-infected cells secrete extracellular vesicles (evs), including exosomes, containing infectious viral rna and proteins. a full-length denv2 genome, detected in arthropod evs, was infectious to naïve mosquito and mammalian cells, including human-skin keratinocytes and bloo ... | 2018 | 29946031 |
| model-based analysis of experimental data from interconnected, row-configured huts elucidates multifaceted effects of a volatile chemical on aedes aegypti mosquitoes. | insecticides used against aedes aegypti and other disease vectors can elicit a multitude of dose-dependent effects on behavioral and bionomic traits. estimating the potential epidemiological impact of a product requires thorough understanding of these effects and their interplay at different dosages. volatile spatial repellent (sr) products come with an additional layer of complexity due to the potential for altered movement of affected mosquitoes and diffusion of volatile particles of the produ ... | 2018 | 29941038 |
| wolbachia enhances insect-specific flavivirus infection in aedes aegypti mosquitoes. | mosquitoes transmit a diverse group of human flaviviruses including west nile, dengue, yellow fever, and zika viruses. mosquitoes are also naturally infected with insect-specific flaviviruses (isfs), a subgroup of the family not capable of infecting vertebrates. although isfs are not medically important, they are capable of altering the mosquito's susceptibility to flaviviruses and may alter host fitness. wolbachia is an endosymbiotic bacterium of insects that when present in mosquitoes limits t ... | 2018 | 29938064 |
| using barcoded zika virus to assess virus population structure in vitro and in aedes aegypti mosquitoes. | arboviruses such as zika virus (zikv, flaviviridae; flavivirus) must replicate in both mammalian and insect hosts possessing strong immune defenses. accordingly, transmission between and replication within hosts involves genetic bottlenecks, during which viral population size and genetic diversity may be significantly reduced. to help quantify these bottlenecks and their effects, we constructed 4 "barcoded" zikv populations that theoretically contain thousands of barcodes each. after identifying ... | 2018 | 29935423 |
| circulation of chikungunya virus in aedes aegypti in maranhão, northeast brazil. | the simultaneous circulation of dengue virus (denv), chikungunya virus (chikv) and zika virus (zikv) arboviruses have placed brazil among the main worldwide endemic areas. brazilian northeast region concentrates the highest incidence of infections caused by chikv and zikv. in maranhão, the second biggest northeastern state, there are cases of human infections caused by these three arboviruses and presence of aedes aegypti and aedes albopictus vectors. in this context, this study aimed to investi ... | 2018 | 29932932 |
| ancient treatment for lice: a source of suggestions for carriers of other infectious diseases? | louse infestation is one of the oldest contagious pestilential diseases of humankind, which has recently re-emerged in several developing countries as well as in homeless individuals and migrants. the present work provides the first phase of an historical excursus of louse remedies based on the classics of pharmaceutical literature, codes, pharmacopoeia and treatises. the second phase involves a literature search, based on the principal medical databases (scifinder, pubmed, google scholar, isi-w ... | 2018 | 29932096 |
| evaluation of aedes aegypti (diptera: culicidae) life table attributes upon chikungunya virus replication reveals impact on egg-laying pathways. | arthropod-borne virus disease cycles constitute interactions among three primary players-the host, the vector, and the virus-in which the virus needs to interact with the host and the vector to establish its survival. while in the host, some arboviruses replicate aggressively, resulting in host pathogenicity, and manifest as a disease condition. these viruses more often utilize the vectors as reservoirs before they are transmitted to the host and therefore do not amplify to as large titers as th ... | 2018 | 29931258 |
| a high-risk zika and dengue transmission hub: virus detections in mosquitoes at a brazilian university campus. | zika virus (zikv) and dengue virus (denv) are mosquito-borne flaviviruses prevalent throughout tropical regions. currently, management of zikv and denv centers on control of the primary vector aedes aegypti. this vector is highly anthropophilic and is therefore prevalent throughout densely urbanised landscapes. a new passive trap for gravid ae. aegypti (gravid aedes trap - gat) was developed for mosquito surveillance. here the different killing agents and the level of transmission of arboviruses ... | 2018 | 29929561 |
| risk factors for the presence of dengue vector mosquitoes, and determinants of their prevalence and larval site selection in dhaka, bangladesh. | dengue viruses are responsible for over 100 million infections a year worldwide and are a public health concern in bangladesh. although risk of transmission is high, data on vector population characteristics are scanty in bangladesh; therefore, a comprehensive prediction of the patterns of local virus transmission is not possible. recognizing these gaps, multi-year entomological surveys were carried out in dhaka, where the disease is most frequently reported. the specific objectives of the prese ... | 2018 | 29928055 |
| vector competence of aedes aegypti, culex tarsalis, and culex quinquefasciatus from california for zika virus. | zika virus (zikv) has emerged since 2013 as a significant global human health threat following outbreaks in the pacific islands and rapid spread throughout south and central america. severe congenital and neurological sequelae have been linked to zikv infections. assessing the ability of common mosquito species to transmit zikv and characterizing variation in mosquito transmission of different zikv strains is important for estimating regional outbreak potential and for prioritizing local mosquit ... | 2018 | 29927940 |
| hydrophobic nanoprecipitates of β-cyclodextrin/avermectins inclusion compounds reveal insecticide activity against aedes aegypti larvae and low toxicity against fibroblasts. | in the present work, hydrophobic nanoprecipitates (hnps) of inclusion complexes formed between β-cyclodextrin (βcd) and the avermectins (avms) named eprinomectin (epri) and ivermectin (iver) were synthesized and characterized, and their larvicidal activity against aedes aegypti and human safety against fibroblasts were evaluated. initially, thermogravimetric analysis/differential thermal analysis data revealed that inclusion increased the thermal stability of avms in the presence of βcd. nuclear ... | 2018 | 29925239 |
| field testing & evaluation of the efficacy & duration of effectiveness of a biolarvicide, bactivec® sc (bacillus thuringiensis var. israelensis sh-14) in bengaluru, india. | different formulations of bacillus thuringiensis var. israelensis (bti) have been tested against different mosquito vectors and other insects for their residual activity. in the present study, the efficacy and residual activity of a new formulation of bti (bactivec suspension concentrate) were evaluated against immature stages of anopheles stephensi liston (diptera: culicidae), aedes aegypti linnaeus (diptera: culicidae) and culex quinquefasciatus say (diptera: culicidae), in natural habitats in ... | 2018 | 29923520 |
| identification of aedes aegypti cis-regulatory elements that promote gene expression in olfactory receptor neurons of distantly related dipteran insects. | sophisticated tools for manipulation of gene expression in select neurons, including neurons that regulate sexually dimorphic behaviors, are increasingly available for analysis of genetic model organisms. however, we lack comparable genetic tools for analysis of non-model organisms, including aedes aegypti, a vector mosquito which displays sexually dimorphic behaviors that contribute to pathogen transmission. formaldehyde-assisted isolation of regulatory elements followed by sequencing (faire-se ... | 2018 | 29996889 |
| tropomyosins in mosquito and house dust mite cross-react at the humoral and cellular level. | aedes aegypti and dermatophagoides pteronyssinus contain important allergens including cross-reactive tropomyosins. however, the functional and clinical relevance of their cross-reactivity is still debated. | 2018 | 29992665 |
| mosquito arbovirus survey in selected areas of kenya: detection of insect-specific virus. | many arboviral outbreaks have occurred in various locations in kenya. entomological surveys are suitable methods for revealing information about circulating arboviruses before human outbreaks are recognized. therefore, mosquitoes were collected in kenya to determine the distribution of arboviruses. | 2018 | 29991925 |
| environmentally-friendly green approach for the production of zinc oxide nanoparticles and their anti-fungal, ovicidal, and larvicidal properties. | green synthesis of nanoparticles can be an important alternative compared to conventional physio-chemical synthesis. we utilized scadoxus multiflorus leaf powder aqueous extract as a capping and stabilizing agent for the synthesis of pure zinc oxide nanoparticles (zno nps). further, the synthesized zno nps were subjected to various characterization techniques. transmission electron microscope (tem) analysis showed an irregular spherical shape, with an average particle size of 31 ± 2 nm. furtherm ... | 2018 | 29986435 |
| molecular aspects of the dengue virus infection process: a review. | at the present time, dengue is one of the most important arboviruses affecting man, becoming a serious global public health problem, especially in subtropical and tropical countries, where environmental conditions favor the development and proliferation of the mosquito aedes aegypti. dengue is caused by a type of flavivírus, which is an enveloped virus of spherical geometry. nowadays, it is one of the diseases with the highest incidence in brazil, reaching the population of all states, regardles ... | 2018 | 29984641 |
| aedes aegypti in the black sea: recent introduction or ancient remnant? | the yellow fever mosquito aedes aegypti transmits viral diseases that have plagued humans for centuries. its ancestral home are forests of africa and ~400-600 years ago it invaded the new world and later europe and asia, causing some of the largest epidemics in human history. the species was rarely detected in countries surrounding the mediterranean sea after the 1950s, but during the last 16 years it re-appeared in madeira, russia and in the eastern coast of the black sea. we genotyped ae. aegy ... | 2018 | 29980229 |
| west nile virus and other mosquito-borne viruses present in eastern europe. | eastern europe (ee) has been severely affected by mosquito-borne viruses (moboviruses). in this review, we summarize the epidemiology of moboviruses, with particular attention to west nile virus (wnv). the study of wnv human cases in ee between 2010 and 2016, revealed that the epidemiology of wnv in ee is complex with the combination of introduction of different wnv strains from lineages 1 and 2, and the establishment of endemic cycles. we found a positive correlation between the risk of wnv re- ... | 2018 | 29979950 |
| both living bacteria and eukaryotes in the mosquito gut promote growth of larvae. | we recently reported that larval stage aedes aegypti and several other species of mosquitoes grow when living bacteria are present in the gut but do not grow when living bacteria are absent. we further reported that living bacteria induce a hypoxia signal in the gut, which activates hypoxia-induced transcription factors and other processes larvae require for growth. in this study we assessed whether other types of organisms induce mosquito larvae to grow and asked if the density of non-living mi ... | 2018 | 29979680 |
| variation in temephos resistance in field populations of aedes aegypti (diptera: culicidae) in the state of sergipe, northeast brazil. | the organophosphate temephos was first used in brazil in the 1960s for the control of aedes aegypti. because of its extensive and longstanding use worldwide, selection for mosquito populations resistant to the chemical has been observed not only in different regions of brazil but also in several parts of the world. the objective of this study was to evaluate the susceptibility of ae. aegypti to the organophosphate temephos, a larvicide used in vector control activities in sergipe/northeast brazi ... | 2018 | 29972557 |
| zika virus: - a review of the main aspects of this type of arbovirosis. | the objective of this study was to integrate findings related to zika virus from the scientific literature. an integrative review of medline was conducted, and data search was performed using the health sciences descriptor zika virus and the following filters: full texts available; studies in humans; full articles; and publications in portuguese, french, english, and spanish. after application of the filters, followed by reading of the titles, abstracts, and full texts, 44 studies were included ... | 2018 | 29972554 |
| the surveillance of chikungunya virus in a temperate climate: challenges and possible solutions from the experience of lazio region, italy. | chikv has become an emerging public health concern in the temperate regions of the northern hemisphere as a consequenceof the expansion of the endemic areas of its vectors (mainly aedes aegypti and aedesalbopictus). in 2017, a new outbreak of chikv was detected in italy with three clusters of autochthonous transmission in the lazio region (central italy), in the cities of anzio, rome, and latina and a secondary cluster in the calabria region (south italy). given the climate characteristics of it ... | 2018 | 30223536 |
| where vectors collide: the importance of mechanisms shaping the realized niche for modeling ranges of invasive aedes mosquitoes. | the vector mosquitoes aedes aegypti (l.), native to africa, and aedes albopictus (skuse), native to asia, are widespread invasives whose spatial distributions frequently overlap. predictive models of their distributions are typically correlative rather than mechanistic, and based on only abiotic variables describing putative environmental requirements despite extensive evidence of competitive interactions leading to displacements. here we review putative roles of competition contributing to dist ... | 2018 | 30220875 |
| differences in the replicative capacities of clinical isolates of dengue virus in c6/36 cells and in urban populations of aedes aegypti from colombia, south america. | dengue, the most prevalent arboviral disease worldwide, is caused by any of the four dengue virus (denv) serotypes that co-circulate constantly in hyperendemic areas such as medellin (colombia), and these serotypes are transmitted by mosquitoes of the genus aedes. in this study, we evaluated the replicative capacity of strains isolated in medellin between 2003 and 2007 in c6/36 cells and in colonies of aedes aegypti collected during 2010-2011 from high or low-incidence areas within the same city ... | 2018 | 30165044 |
| direct nucleic acid analysis of mosquitoes for high fidelity species identification and detection of wolbachia using a cellphone. | manipulation of natural mosquito populations using the endosymbiotic bacteria wolbachia is being investigated as a novel strategy to reduce the burden of mosquito-borne viruses. to evaluate the efficacy of these interventions, it will be critical to determine wolbachia infection frequencies in aedes aegypti mosquito populations. however, current diagnostic tools are not well-suited to fit this need. morphological methods cannot identify wolbachia, immunoassays often suffer from low sensitivity a ... | 2018 | 30161131 |
| regulation of midgut cell proliferation impacts aedes aegypti susceptibility to dengue virus. | aedes aegypti is the vector of some of the most important vector-borne diseases like dengue, chikungunya, zika and yellow fever, affecting millions of people worldwide. the cellular processes that follow a blood meal in the mosquito midgut are directly associated with pathogen transmission. we studied the homeostatic response of the midgut against oxidative stress, as well as bacterial and dengue virus (denv) infections, focusing on the proliferative ability of the intestinal stem cells (isc). i ... | 2018 | 29782512 |
| zika virus: report from the task force on tropical diseases by the world federation of societies of intensive and critical care medicine. | zika fever is an acute infectious disease caused by the zika virus (zikv), an rna virus belonging to the genus flavivirus. zikv can be transmitted by bites from aedes aegypti and aedes albopictus species, sexual activity, blood transfusion and from mother to fetus during pregnancy and delivery. a total of 50 territories and countries in the americas had reported zikv infections. for those with symptoms, the presentation is similar to dengue fever with body aches, joint pain, fatigue, malaise, fe ... | 2018 | 29779827 |
| genome sequence analysis of a novel bacillus thuringiensis strain blb406 active against aedes aegypti larvae, a novel potential bioinsecticide. | blb406 is a novel isolate of bacillus thuringiensis with a larvicidal activity against aedes aegypti larvae. it displays original plasmidic and crystal protein patterns. the present work reported molecular and bioinformatic analyses for the genome sequence of blb406 using miseq illumina next-generation sequencing technology. the reads were assembled by velvet tool. using rast program and pgaap, the genome of blb406 strain was shown to contain 6297 genes corresponding to 5924 protein coding seque ... | 2018 | 29778876 |
| chemical profile and pharmacological effects of the resin and essential oil from bursera slechtendalii: a medicinal "copal tree" of southern mexico. | this study reports on the volatile profile and pharmacological activities of the essential oil and resin from bursera slechtendalii, an aromatic medicinal tree commercialized in southern mexico. the essential oil contained 25 volatiles including p-cymen-8-ol (25.4-35.7%), n-hexyl hexanoate (6.8-17.6%) and n-octyl hexanoate (7.6-14.8%), whereas the crystallized resin contained 14 volatiles, including n-octyl acetate (29.6-34.2%), limonene (15.8-18.7%) and n-octyl butyrate (12.6-17-6%). the inhala ... | 2018 | 29777752 |
| modeling dengue vector population using remotely sensed data and machine learning. | mosquitoes are vectors of many human diseases. in particular, aedes ægypti (linnaeus) is the main vector for chikungunya, dengue, and zika viruses in latin america and it represents a global threat. public health policies that aim at combating this vector require dependable and timely information, which is usually expensive to obtain with field campaigns. for this reason, several efforts have been done to use remote sensing due to its reduced cost. the present work includes the temporal modeling ... | 2018 | 29777650 |
| use of bead-based serologic assay to evaluate chikungunya virus epidemic, haiti. | the index case of chikungunya virus (chikv) in haiti was reported during early 2014; the vector, the pervasive aedes aegypti mosquito, promoted rapid spread throughout the country. during december 2014-february 2015, we collected blood samples from 4,438 persons at 154 sites (62 urban, 92 rural) throughout haiti and measured chikv igg by using a multiplex bead assay. overall chikv seroprevalence was 57.9%; differences between rural (mean 44.9%) and urban (mean 78.4%) areas were pronounced. logis ... | 2018 | 29774861 |
| the influence of urban heat islands and socioeconomic factors on the spatial distribution of aedes aegypti larval habitats. | we addressed the potential associations among the temporal and spatial distribution of larval habitats of aedes (stegomyia) aegypti, the presence of urban heat islands and socioeconomic factors. data on larval habitats were collected in santa bárbara d'oeste, são paulo, brazil, from 2004 to 2006, and spatial and temporal variations were analysed using a wavelet-based approach. we quantified urban heat islands by calculating surface temperatures using the results of wavelet analyses and grey leve ... | 2018 | 29772891 |
| urban environmental clustering to assess the spatial dynamics of aedes aegypti breeding sites. | the identification of aedes aegypti breeding hotspots in urban areas is crucial for the rational design of control strategies against this disease vector. remote sensing and geographic information systems offer valuable tools for mapping habitat suitability of a given area. however, predicting species occurrences by means of probability distribution maps based on transversal entomological surveys has limited utility for local authorities. the aim of the present study was to carefully examine the ... | 2018 | 29772886 |
| encapsidated host factors in alphavirus particles influence midgut infection of aedes aegypti. | transmission of mosquito-borne viruses requires the efficient infection of both a permissive vertebrate host and a competent mosquito vector. the infectivity of sindbis virus (sinv), the type species of the alphavirus genus, is influenced by both the original and new host cell. we have shown that infection of vertebrate cells by sinv, chikungunya virus (chikv), and ross river virus (rrv) produces two subpopulations of virus particles separable based on density. in contrast, a single population o ... | 2018 | 29772674 |
| tracking aedes aegypti (diptera: culicidae) larval behavior across development: effects of temperature and nutrients on individuals' foraging behavior. | immature mosquitoes alter their foraging behavior in response to variation in nutrients, predators, and temperature, with consequences on the adult stage where pathogens are transmitted. these patterns of behavior have not been described with respect to both developmental stage and environmental variation, nor has behavior been examined within an individual across instars. we hypothesized that individual larvae have distinct behavioral syndromes, and predict that the rank of foraging activity in ... | 2018 | 29771372 |
| niche conservatism of aedes albopictus and aedes aegypti - two mosquito species with different invasion histories. | biological invasions have been associated with niche changes; however, their occurrence is still debated. we assess whether climatic niches between native and non-native ranges have changed during the invasion process using two globally spread mosquitoes as model species, aedes albopictus and aedes aegypti. considering the different time spans since their invasions (>300 vs. 30-40 years), niche changes were expected to be more likely for ae. aegypti than for ae. albopictus. we used temperature a ... | 2018 | 29769652 |
| ornamental bromeliads of miami-dade county, florida are important breeding sites for aedes aegypti (diptera: culicidae). | a major public health concern is the emergence and geographical spread of vector-borne diseases such as zika and yellow fever. ornamental bromeliads retaining water in their leaf axils represent potential breeding sites for mosquitoes. as the role of ornamental bromeliads in breeding aedes aegypti in miami-dade county, florida is unknown, we hypothesize that ornamental bromeliads are important breeding sites for ae. aegypti. our objective was to survey bromeliads in areas with high densities of ... | 2018 | 29769105 |
| efficacy of the main repellents available in the brazilian market against aedes aegypti bites under concentrations applied to pediatric populations. | 2018 | 29768569 | |
| ns1 codon usage adaptation to humans in pandemic zika virus. | zika virus (zikv) was recognised as a zoonotic pathogen in africa and southeastern asia. human infections were infrequently reported until 2007, when the first known epidemic occurred in micronesia. after 2013, the asian lineage of zikv spread along the pacific islands and americas, causing severe outbreaks with millions of human infections. the recent human infections of zikv were also associated with severe complications, such as an increase in cases of guillain-barre syndrome and the emergenc ... | 2018 | 29768530 |
| pyrethroid insecticides maintain repellent effect on knock-down resistant populations of aedes aegypti mosquitoes. | pyrethroid-treated clothing is commonly worn for protection against mosquitoes; pyrethroids are both insecticides and repellents. pyrethroid resistance has become increasingly common in aedes aegypti, the vector of dengue, zika, and other arboviruses, but it is not clear whether resistance is associated with reductions in repellency. in order to determine whether long-lasting permethrin impregnated (llpi) clothing is protective, we used aedes aegypti from new orleans, la (pyrethroid-sensitive) a ... | 2018 | 29763445 |
| effects of light and temperature on daily activity and clock gene expression in two mosquito disease vectors. | most organisms feature an endogenous circadian clock capable of synchronization with their environment. the most well-known synchronizing agents are light and temperature. the circadian clock of mosquitoes, vectors of many pathogens, drives important behaviors related to vectoral capacity, including oviposition, host seeking, and hematophagy. main clock gene expression, as well as locomotor activity patterns, has been identified in aedes aegypti and culex quinquefasciatus under artificial light- ... | 2018 | 29761749 |
| threats of zika virus transmission for asia and its hindu-kush himalayan region. | asia and its hindu kush himalayan (hkh) region is particularly vulnerable to environmental change, especially climate and land use changes further influenced by rapid population growth, high level of poverty and unsustainable development. asia has been a hotspot of dengue fever and chikungunya mainly due to its dense human population, unplanned urbanization and poverty. in an urban cycle, dengue virus (denv) and chikungunya virus (chikv) are transmitted by aedes aegypti and ae. albopictus mosqui ... | 2018 | 29759076 |
| aedes aegypti(linnaeus) larvae from dengue outbreak areas in selangor showing resistance to pyrethroids but susceptible to organophosphates. | the resistance status of selangor aedes aegypti (linnaeus) larvae against four major groups of insecticides (i.e., organochlorines, carbamates, organophosphates and pyrethroids) was investigated. aedes aegypti were susceptible against temephos (organophosphate), although resistance (rr50 = 0.21-2.64) may be developing. the insecticides susceptibility status of ae. aegypti larvae were found heterogeneous among the different study sites. results showed that ae. aegypti larvae from klang, sabak ber ... | 2018 | 29758171 |
| a review of the ongoing research on zika virus treatment. | the zika fever is an arboviral disease resulting from the infection with zika virus (zikv). the virus is transmitted to humans by the bite of aedes mosquitos, mainly aedes aegypti and aedes albopictus. zikv has been detected for decades in african and asian regions and, since 2007, has spread to other continents; among them, infections are most reported in the americas. this can be explained by the presence of vectors in highly populated and tropical regions where people are susceptible to conta ... | 2018 | 29758005 |
| two novel mutations in the voltage-gated sodium channel associated with knockdown resistance (kdr) in the dengue vector aedes aegypti in vietnam. | 2018 | 29757514 | |
| diel patterns of aedes aegypti (diptera: culicidae) after resurgence in st. augustine, florida as collected by a mechanical rotator trap. | 2018 | 29757509 | |
| mosquito traps for urban surveillance: collection efficacy and potential for use by citizen scientists. | mosquito-borne diseases are a pervasive public health problem on a global scale, and effective management of them requires well-designed surveillance programs for both vectors and pathogens. mosquito traps are a common component of such programs, and their reach can be expanded by engaging citizen scientists. in this study in a southern australian city, we compared the mosquito collection efficacy of two types of traps and assessed their suitability for use in citizen science programs. bg sentin ... | 2018 | 29757507 |
| controversies over the scientific name of the principal mosquito vector of yellow fever virus - expediency versus validity. | the history of the scientific name of the yellow fever mosquito, the vector of yellow fever virus, ranges from 1757 to the early twenty-first century. in his 1757 work iter palaestinum, frederic hasselquist gave the name culex aegypti to a mosquito species responsible for fierce attacks on humans in egypt. that name was never later ascribed to hasselquist as author, but to linnaeus, although the name never appeared in any of linnaeus' publications. in cuba, at the end of the nineteenth century, ... | 2018 | 29757506 |
| effects of scarcity and excess of larval food on life history traits of aedes aegypti (diptera: culicidae). | few studies have assessed the effects of food scarcity or excess on the life history traits of aedes aegypti (l.) (diptera: culicidae) independently from larval density. we assessed immature survival, development time, and adult size in relation to food availability. we reared cohorts of 30 ae. aegypti larvae from newly hatched to adult emergence with different food availability. food conditions were kept constant by transferring larvae each day to a new food solution. immature development was c ... | 2018 | 29757503 |
| de novo dna synthesis in aedes aegypti midgut cells as a complementary strategy to limit dengue viral replication. | aedes aegypti is the main vector of dengue virus, carrying the virus during the whole mosquito life post-infection. few mosquito fitness costs have been associated to the virus infection, thereby allowing for a swift dissemination. in order to diminish the mosquito population, public health agency use persistent chemicals with environmental impact for disease control. most countries barely use biological controls, if at all. with the purpose of developing novel dengue control strategies, a detai ... | 2018 | 29755433 |
| sargassum wightii-synthesized zno nanoparticles - from antibacterial and insecticidal activity to immunostimulatory effects on the green tiger shrimp penaeus semisulcatus. | the green synthesis of metal nanoparticles using phytochemical from marine seaweeds is a fast-growing research field in nanotechnology. here, the biosynthesis of zinc oxide nanoparticles was achieved using the hot water extract of sargassum wightii. the hot water extract prepared from s. wightii (h sw) and zno nps were studied by uv-visible and ftir spectroscopy, sem and xrd. then, both products were evaluated for antibiofilm activity towards aquatic pathogens. the nanoparticles' immunostimulati ... | 2018 | 29754050 |
| dynamics of dengue disease with human and vector mobility. | dengue is a vector borne disease transmitted to humans by aedes aegypti mosquitoes carrying virus of different serotypes. dengue exhibits complex spatial and temporal dynamics, influenced by various biological, human and environmental factors. in this work, we study the dengue spread for a single serotype (denv-1) including statistical models of human mobility with exponential step length distribution, by using reaction-diffusion equations and stochastic cellular automata (sca) approach. we anal ... | 2018 | 29751893 |
| a wolbachia triple-strain infection generates self-incompatibility in aedes albopictus and transmission instability in aedes aegypti. | artificially-introduced transinfections of the intracellular bacterium wolbachia pipientis have the potential to reduce the vectorial capacity of mosquito populations for viruses such as dengue and chikungunya. aedes albopictus has two native strains of wolbachia, but their replacement with the non-native wmel strain blocks transmission of both viruses. the pattern of cytoplasmic incompatiiblity generated by wmel with wild-types is bidirectional. novel-plus-native-strain co-infection is predicte ... | 2018 | 29751814 |
| molecular responses to the zika virus in mosquitoes. | the zika virus (zikv), originally discovered in 1947, did not become a major concern until the virus swept across the pacific and into the americas in the last decade, bringing with it news of neurological complications and birth defects in zikv affected areas. this prompted researchers to dissect the molecular interactions between zikv and the mosquito vector in an attempt to better understand not only the changes that occur upon infection, but to also identify molecules that may potentially en ... | 2018 | 29751526 |
| effect of uv-b irradiation on water-suspended metarhizium anisopliae s.l. (hypocreales: clavicipitaceae) conidia and their larvicidal activity in aedes aegypti (diptera: culicidae). | ultraviolet (uv) radiation is a key limiting factor for biological pest control with entomopathogenic fungi. while little is known about the impact of uv on metarhizium anisopliae metchnikoff (sorokin) (hypocreales: clavicipitaceae) conidia in aquatic mosquito-breeding sites, this study determined the effect of uv-b on the viability and virulence of m. anisopliae sensu lato (s.l.) strain ip 46 in the laboratory against aedes aegypti (l.) (diptera: culicidae) larvae. conidia were treated in cups ... | 2018 | 29750411 |
| experimental zika virus infection in aedes aegypti: susceptibility, transmission & co-infection with dengue & chikungunya viruses. | there are reports about the susceptibility of aedes mosquitoes to zikv from various countries, however, no such information is available from indian sub-continent, although, high level of group cross-reactivity of zikv with other flaviviruses has been reported. during outbreak situations, many cases of dengue (den) and chikungunya (chik) are reported. in such scenario, vector mosquitoes are likely to get co-infection/secondary-infection with one or other virus. the present study was carried out ... | 2018 | 29749366 |
| a new "american" subgroup of african-lineage chikungunya virus detected in and isolated from mosquitoes collected in haiti, 2016. | as part of on-going arboviral surveillance activity in a semi-rural region in haiti, chikungunya virus (chikv)-positive mosquito pools were identified in 2014 (the peak of the caribbean asian-clade epidemic), and again in 2016 by rt-pcr. in 2014, chikv was only identified in aedes aegypti (11 positive pools/124 screened). in contrast, in sampling in 2016, chikv was not identified in ae. aegypti, but, rather, in (a) a female aedes albopictus pool, and (b) a female culex quinquefasciatus pool. gen ... | 2018 | 29746539 |
| seasonal temperature variation influences climate suitability for dengue, chikungunya, and zika transmission. | dengue, chikungunya, and zika virus epidemics transmitted by aedes aegypti mosquitoes have recently (re)emerged and spread throughout the americas, southeast asia, the pacific islands, and elsewhere. understanding how environmental conditions affect epidemic dynamics is critical for predicting and responding to the geographic and seasonal spread of disease. specifically, we lack a mechanistic understanding of how seasonal variation in temperature affects epidemic magnitude and duration. here, we ... | 2018 | 29746468 |
| atypical neurological manifestations of chikungunya fever: two case reports. | chikungunya fever (chik) is an arboviral disease which is transmitted by a mosquito bite (aedes aegypti). fever, polyarthralgia, and maculopapular rash are hallmark clinical manifestations of this disease. these manifestations are self-liming and complete recovery is seen in most of the cases. however, atypical and lethal complications such as myocarditis, hepatitis, guillain-barre syndrome (gbs), and meningoencephalitis have been reported in few cases of chik. we hereby report two cases of chik ... | 2018 | 29743772 |
| complete genome of aedes aegypti anphevirus in the aag2 mosquito cell line. | a novel negative-sense rna virus, aedes aegypti anphevirus, was recently identified in wild aedes aegypti mosquitoes. we show that this virus is also present in the aag2 aedes aegypti cell line and characterize its complete genome and evolutionary history. the aedes aegypti anphevirus genome is estimated to be 12 916 nucleotides in length, contains four genes and has a genome structure similar to that of other anpheviruses. phylogenetically, aedes aegypti anphevirus falls within an unclassified ... | 2018 | 29741476 |
| expression of a synthetic gene for the major cytotoxin (cyt1aa) of bacillus thuringiensis subsp. israelensis in the chloroplast of wild-type chlamydomonas. | chlamydomonas reinhardtii (chlamydomonas) strains that are toxic to mosquito larvae because they express chloroplast transgenes that are based on the mosquitocidal proteins of bacillus thuringiensis subsp. israelensis (bti) could be very useful in mosquito control. chlamydomonas has several advantages for this approach, including genetic controls not generally available with industrial algae. the bti toxin is produced by sporulating bacteria and has been used for mosquito control for >30 years w ... | 2018 | 29738473 |
| crystal structure of a novel kunitz type inhibitor, alocasin with anti-aedes aegypti activity targeting midgut proteases. | the pesticidal properties of many kunitz-type inhibitors have been reported previously; however, the mechanism of action is not well established. in this study, the activity of alocasin against aedes aegypti is demonstrated and the structure-activity relationship of this kunitz-type inhibitor is explained through x-ray structure analyses. | 2018 | 29737039 |
| antibodies against chikungunya in northern mozambique during dengue outbreak, 2014. | an outbreak of dengue and high densities of aedes aegypti were reported in 2014 in northern mozambique, suggesting an increased risk for other arboviruses such as chikungunya virus (chikv) in this region. the aim of this study was to investigate the occurrence of chikv during an outbreak of dengue virus (denv) in pemba city in northern mozambique in 2014. febrile patients (n = 146) seeking medical attention at the pemba provincial hospital between march and april 2014 were enrolled in this study ... | 2018 | 29733254 |
| male contributions during mating increase female survival in the disease vector mosquito aedes aegypti. | aedes aegypti is a vector of medically important viruses including those causing zika, dengue, and chikungunya. during mating, males transfer a number of proteins and other molecules to the female and these components of the male ejaculate are essential in shifting female post-mating behaviors in a number of insect species. because these molecules are highly variable by species, and female post-mating behavior by species is also varied, behavioral assays testing the function of the ejaculate are ... | 2018 | 29729859 |
| improving the delivery and efficiency of fungus-impregnated cloths for control of adult aedes aegypti using a synthetic attractive lure. | entomopathogenic fungi are highly promising agents for controlling aedes aegypti mosquitoes. deploying fungus-impregnated black cloths in pet traps efficiently reduced ae. aegypti female survival rates under intra-domicile conditions. with the aim of further increasing the effectiveness of the traps, the addition of attractive lures to fungus-impregnated traps was evaluated. | 2018 | 29728121 |
| advising a woman with suspected zika virus infection. | the zika virus (zikv) epidemic is spreading: 67 countries are now reporting transmission, and over 2,000 cases of congenital zika syndrome (czs) have been confirmed. the heaviest burden has been borne by those living where poverty, poor infrastructure, and lack of access to health services are common and the penetration of aedes aegypti is high. because most cases are asymptomatic, the most dramatic signs of the disease appear through the czs cases. in spite of the need for disaggregated epidemi ... | 2018 | 29724698 |
| larval density mediates knockdown resistance to pyrethroid insecticides in adult aedes aegypti. | understanding mechanisms driving insecticide resistance in vector populations remains a public health priority. to date, most research has focused on the genetic mechanisms underpinning resistance, yet it is unclear what role environmental drivers may play in shaping phenotypic expression. one of the key environmental drivers of aedes aegypti mosquito population dynamics is resource-driven intraspecific competition at the larval stage. we experimentally investigated the role of density-dependent ... | 2018 | 29724237 |
| contributions from the silent majority dominate dengue virus transmission. | despite estimates that, each year, as many as 300 million dengue virus (denv) infections result in either no perceptible symptoms (asymptomatic) or symptoms that are sufficiently mild to go undetected by surveillance systems (inapparent), it has been assumed that these infections contribute little to onward transmission. however, recent blood-feeding experiments with aedes aegypti mosquitoes showed that people with asymptomatic and pre-symptomatic denv infections are capable of infecting mosquit ... | 2018 | 29723307 |
| wolbachia significantly impacts the vector competence of aedes aegypti for mayaro virus. | wolbachia, an intracellular endosymbiont present in up to 70% of all insect species, has been suggested as a sustainable strategy for the control of arboviruses such as dengue, zika and chikungunya. as mayaro virus outbreaks have also been reported in latin american countries, the objective of this study was to evaluate the vector competence of brazilian field-collected ae. aegypti and the impact of wolbachia (wmel strain) upon this virus. our in vitro studies with aag2 cells showed that mayaro ... | 2018 | 29720714 |
| vector competence of certain culex and aedes mosquitoes for the chittoor virus, the indian variant of the batai virus. | chittoor virus (chitv), a mosquito-borne bunyavirus (orthobunyavirus: bunyaviridae) isolated in india, has been found to be antigenically close to the batai virus (batv), which has a wide distribution across asia, europe, and africa. the latter virus causes influenza-like illness in humans and mild illness in sheep and goats. batv has been involved in genetic reassortment with other bunyaviruses, generating novel genome combinations and causing severe clinical manifestations including hemorrhagi ... | 2018 | 29718685 |
| high throughput discovery of protein variants using proteomics informed by transcriptomics. | proteomics informed by transcriptomics (pit), in which proteomic ms/ms spectra are searched against open reading frames derived from de novo assembled transcripts, can reveal previously unknown translated genomic elements (tges). however, determining which tges are truly novel, which are variants of known proteins, and which are simply artefacts of poor sequence assembly, is challenging. we have designed and implemented an automated solution that classifies putative tges by comparing to referenc ... | 2018 | 29718325 |
| dehydration prompts increased activity and blood feeding by mosquitoes. | current insights into the mosquito dehydration response rely on studies that examine specific responses but ultimately fail to provide an encompassing view of mosquito biology. here, we examined underlying changes in the biology of mosquitoes associated with dehydration. specifically, we show that dehydration increases blood feeding in the northern house mosquito, culex pipiens, which was the result of both higher activity and a greater tendency to land on a host. similar observations were noted ... | 2018 | 29717151 |
| efficacy of larvicides for the control of dengue, zika, and chikungunya vectors in an urban cemetery in southern mexico. | many countries in latin america have recently experienced outbreaks of zika and chikungunya fever, in additional to the usual burden imposed by dengue, all of which are transmitted by aedes aegypti in this region. to identify potential larvicides, we determined the toxicity of eight modern insecticides to a. aegypti larvae from a colony that originated from field-collected insects in southern mexico. the most toxic compounds were pyriproxyfen (which prevented adult emergence) and λ-cyhalothrin, ... | 2018 | 29713901 |
| parallel evolution of vgsc mutations at domains is6, iis6 and iiis6 in pyrethroid resistant aedes aegypti from mexico. | aedes aegypti is the primary urban mosquito vector of viruses causing dengue, zika and chikungunya fevers -for which vaccines and effective pharmaceuticals are still lacking. current strategies to suppress arbovirus outbreaks include removal of larval-breeding sites and insecticide treatment of larval and adult populations. insecticidal control of ae. aegypti is challenging, due to a recent rapid global increase in knockdown-resistance (kdr) to pyrethroid insecticides. widespread, heavy use of p ... | 2018 | 29712956 |
| identification of candidate iron transporters from the zip/znt gene families in the mosquito aedes aegypti. | mosquito-transmitted viral pathogens, such as dengue and zika, afflict tens of thousands of people every year. these viruses are transmitted during the blood-feeding process that is required for mosquito reproduction, the most important vector being aedes aegypti. while vertebrate blood is rich in protein, its high iron content is potentially toxic to mosquitoes. although iron transport and sequestration are essential in the reproduction of vector mosquitoes, we discovered that culicine mosquito ... | 2018 | 29706902 |
| dengue fever in lebanon: first confirmed case since 1945 and review from the region. | lebanon yearly witnesses a high flux of expatriates and workers from dengue virus (denv) endemic regions. multiple cases of dengue fever have been documented at the american university of beirut medical center (aubmc) in travellers to endemic regions. given the presence of the aedes aegypti mosquito in lebanon, introduction of denv to the country is highly likely. we report a case of denv infection in lebanon diagnosed in april 2012 in a patient with no prior travel history. the patient presente ... | 2018 | 31851640 |
| [applications of the crispr/cas9 system in insects]. | the crispr/cas9 (clustered regularly interspaced short palindromic repeat/crispr-associated) system guides cas9 to specific genomic locations by a short rna search string. this technology enables the systematic interrogation of mammalian genome editing, repairing damaged genes, silencing harmful genes and improving quality traits. in recent years, with the introduction of the crispr/cas9 system for easy, fast and efficient genetic modification, it has been possible to conduct meaningful function ... | 2018 | 29704373 |
| structural characterization of bacillus licheniformis dahb1 exopolysaccharide-antimicrobial potential and larvicidal activity on malaria and zika virus mosquito vectors. | microbial polysaccharides produced by marine species play a key role in food and cosmetic industry, as they are nontoxic and biodegradable polymers. this investigation reports the isolation of exopolysaccharide from bacillus licheniformis dahb1 and its biomedical applications. bacillus licheniformis dahb1 exopolysaccharide (bl-eps) was extracted using the ethanol precipitation method and structurally characterized. ftir and 1h-nmr pointed out the presence of various functional groups and primary ... | 2018 | 29704178 |
| host genotype and environment affect the trade-off between horizontal and vertical transmission of the parasite edhazardia aedis. | if a parasite is able to transmit horizontally or vertically, which transmission mode will it choose? we investigated how the growth conditions and the genotype of the mosquito aedes aegypti affect the transmission mode of the parasite edhazardia aedis. | 2018 | 29699504 |
| ammonia excretion in an osmoregulatory syncytium is facilitated by aeamt2, a novel ammonia transporter in aedes aegypti larvae. | the larvae of the mosquito aedes aegypti inhabit ammonia rich septic tanks in tropical regions of the world that make extensive use of these systems, explaining the prevalence of disease during dry seasons. since ammonia (nh3/[formula: see text]) is toxic to animals, an understanding of the physiological mechanisms of ammonia excretion permitting the survival of a. aegypti larvae in high ammonia environments is important. we have characterized a novel ammonia transporter, aeamt2, belonging to th ... | 2018 | 29695971 |
| a chikungunya virus trans-replicase system reveals the importance of delayed nonstructural polyprotein processing for efficient replication complex formation in mosquito cells. | chikungunya virus (chikv) is a medically important alphavirus that is transmitted by aedes aegypti and aedes albopictus mosquitoes. the viral replicase complex consists of four nonstructural proteins (nsps) expressed as a polyprotein precursor and encompasses all enzymatic activities required for viral rna replication. nsps interact with host components of which most are still poorly understood, especially in mosquitos. a chikv trans-replicase system that allows the uncoupling of rna replication ... | 2018 | 29695432 |
| effects of desiccation stress on adult female longevity in aedes aegypti and ae. albopictus (diptera: culicidae): results of a systematic review and pooled survival analysis. | transmission dynamics of mosquito-borne viruses such as dengue, zika and chikungunya are affected by the longevity of the adult female mosquito. environmental conditions influence the survival of adult female aedes mosquitoes, the primary vectors of these viruses. while the association of temperature with aedes mortality has been relatively well-explored, the role of humidity is less established. the current study's goals were to compile knowledge of the influence of humidity on adult survival i ... | 2018 | 29695282 |
| dna barcoding of morphologically characterized mosquitoes belonging to the subfamily culicinae from sri lanka. | vectors of mosquito-borne diseases in sri lanka, except for malaria, belong to the subfamily culicinae, which includes nearly 84% of the mosquito fauna of the country. hence, accurate and precise species identification of culicine mosquitoes is a crucial factor in implementing effective vector control strategies. during the present study, a combined effort using morphology and dna barcoding was made to characterize mosquitoes of the subfamily culicinae for the first time from nine districts of s ... | 2018 | 29695263 |
| characterization of a western pacific zika virus strain in australian aedes aegypti. | zika virus (zikv) is a globally emerging arbovirus responsible for widespread epidemics in the western pacific, the americas, and asia. the virus predominately circulates in urban transmission cycles between aedes aegypti and humans. australia is considered at risk to outbreaks of zikv due to the presence of a. aegypti populations in northern areas of the state of queensland. furthermore, close proximity to epidemic regions has led to almost 50% of imported cases reported since 2012 originating ... | 2018 | 29694294 |
| neurotropism and behavioral changes associated with zika infection in the vector aedes aegypti. | understanding zika virus infection dynamics is essential, as its recent emergence revealed possible devastating neuropathologies in humans, thus causing a major threat to public health worldwide. recent research allowed breakthrough in our understanding of the virus and host pathogenesis; however, little is known on its impact on its main vector, aedes aegypti. here we show how zika virus targets aedes aegypti's neurons and induces changes in its behavior. results are compared to dengue virus, a ... | 2018 | 29691362 |
| dengue virus infection induces chromatin remodeling at locus aael006536 in the midgut of aedes aegypti. | to identify and characterize aedes aegypti's aael006536 gene proximal upstream cis-regulatory sequences activated by dengue virus infection. | 2018 | 29689655 |