Publications

characteristics of motive force derived from trajectory analysis of amoeba proteus.	we used a monochromatic charge-coupled-device camera to observe the migration behavior of amoeba proteus every 5 s over a time course of 10000 s in order to investigate the characteristics of its centroid movement (cell velocity) over the long term. fourier transformation of the time series of the cell velocity revealed that its power spectrum exhibits a lorentz type profile with a relaxation time of a few hundred seconds. moreover, some sharp peaks were found in the power spectrum, where the ra ...	2007	17351734
surveillance of antimicrobial susceptibility of urinary pathogens in a tertiary care hospital.		2007	17342301
role of ser11 in the stabilization of the structure of ochrobactrum anthropi glutathione transferase.	gsts (glutathione transferases) are a multifunctional group of enzymes, widely distributed and involved in cellular detoxification processes. in the xenobiotic-degrading bacterium ochrobactrum anthropi, gst is overexpressed in the presence of toxic concentrations of aromatic compounds such as 4-chlorophenol and atrazine. we have determined the crystal structure of the gst from o. anthropi (oagst) in complex with gsh. like other bacterial gsts, oagst belongs to the beta class and shows a similar ...	2007	17223798
the first structure of a cold-active catalase from vibrio salmonicida at 1.96 a reveals structural aspects of cold adaptation.	the cold-adapted catalase from the fish-pathogenic bacterium vibrio salmonicida (vsc) has recently been characterized and shown to be two times more catalytically efficient compared with catalase from the mesophilic human pathogen proteus mirabilis [pmc; lorentzen et al. (2006), extremophiles, 10, 427-440]. vsc is also less temperature-stable, with a half-life of 5 min at 333 k compared with 50 min for pmc. this was the background for solving the crystal structure of the cold-adapted vsc to 1.96 ...	2007	17242507
interspecies spread of ctx-m-32 extended-spectrum beta-lactamase and the role of the insertion sequence is1 in down-regulating bla ctx-m gene expression.	to characterize the extended-spectrum beta-lactamases (esbls) as well as their genetic environment in different isolates of enterobacteriaceae from a patient with repeated urinary tract infections.	2007	17332005
digestive tract microbiota in healthy volunteers.	the aim of this study was to standardize the methods of sample collection of mucus from the digestive tract and to determine the microbiota in healthy volunteers from brazil, collecting samples from the mouth, esophagus, stomach, duodenum, jejunum, ileum, colon, and rectum.	2007	17334549
amoeba proteus displays a walking form of locomotion.	this report deals with observations on the directional locomotion of amoeba before and after fixation and scanning electron microscopy. the study was aimed at visualization of the stepwise events of directional movements. after the analysis of the data it is proposed that the amoeba undergoes a sequence of movement events that can be defined as a walking form of locomotion.	2007	17336550
pericardial tamponade masquerading as septic shock.	a 53-year-old man with steroid dependent rheumatoid arthritis presented with fever and serous articular drainage. oral antibiotics were initially prescribed. subsequent hemodynamic instability was attributed to septic shock. further evaluation revealed a pericardial effusion with tamponade. pericardiocentesis of purulent fluid promptly corrected the hypotension. proteus mirabilis was later isolated from both the infected joint and the pericardial fluid. this is the first report of combined prote ...	2007	17356998
antiviral and antimicrobial profiles of selected isoquinoline alkaloids from fumaria and corydalis species.	in the current study, 33 isoquinoline alkaloids belonging to protopine-, benzylisoquinoline-, benzophenanthridine-, spirobenzylisoquinoline-, phthalideisoquinoline-, aporphine-, protoberberine-, cularine-, and isoquinolone-types as well as 7 derivatives of them obtained from some fumaria and corydalis species growing in turkey have been evaluated for their in vitro antiviral and antimicrobial activities. both dna virus herpes simplex (hsv) and rna virus parainfluenza (pi-3) were employed for ant ...	2007	17425100
detection of extended-spectrum beta-lactamases among enterobacteriaceae by use of semiautomated microbiology systems and manual detection procedures.	three commercially available microbiology identification and susceptibility testing systems were compared with regard to their ability to detect extended-spectrum beta-lactamase (esbl) production in enterobacteriaceae, i.e., the phoenix automated microbiology system (bd diagnostic systems, sparks, md), the vitek 2 system (biomérieux, marcy l'etoile, france), and the microscan walkaway-96 system (dade behring, inc., west sacramento, ca), using routine testing panels. one hundred fifty putative es ...	2007	17287329
in vitro activity of ceftibuten at sub-inhibitory concentrations in comparison with other antibiotics against respiratory and urinary tract pathogens.	some new features of the in vitro activity of ceftibuten, an oral third generation cephalosporin, have been studied in reference to respiratory and urinary tract pathogens included in its antibacterial spectrum. at 0.25xmic (minimum inhibitory concentration) and 0.5xmic levels, ceftibuten was able to affect the biofilm production in 2/3 of both escherichia coli and proteus mirabilis strains, and reduced the number of strains capable of adhering to epithelial cells by about 35% in comparison to t ...	2007	17434823
increasing resistance according to patient's age and sex in escherichia coli isolated from urine in italy.	the prevalence of escherichia coli among the uropathogens routinely isolated in non-hospital laboratories (labs) and its susceptibility profiles were investigated. thirty-three labs were selected throughout italy. in vitro assays were performed by means of disk diffusion according to the clsi. females were prevalent (79.9%) and the mean patient age was 58.6 (sd 20.4) years. overall, the prevalence of e. coli was 55.3% (1375 strains), with enterococcus spp 10.2 %, proteus mirabilis 4.8%, coagulas ...	2007	17434824
potential integration sites of the salmonella genomic island 1 in proteus mirabilis and other bacteria.		2007	17293370
antibacterial activity of snake, scorpion and bee venoms: a comparison with purified venom phospholipase a2 enzymes.	venoms of snakes, scorpions, bees and purified venom phospholipase a(2) (pla(2)) enzymes were examined to evaluate the antibacterial activity of purified venom enzymes as compared with that of the crude venoms.	2007	17309613
multifocal proteus mirabilis osteomyelitis requiring bilateral amputation in an hiv-positive patient.	we present a rare case of multifocal proteus mirabilis osteomyelitis in an hiv-positive patient. despite the patient's good immune status as assessed by her cd4 cell count and the aggressive treatment, she eventually underwent bilateral above-knee amputations to eradicate the infection. multifocal proteus mirabilis osteomyelitis can have an unpredictable clinical course with a severe outcome in hiv-positive patients.	2007	17322447
mild and delayed-onset proteus syndrome.		2007	17337412
antibacterial activities of emblica officinalis and coriandrum sativum against gram negative urinary pathogens.	present investigation is focused on antibacterial potential of aqueous infusions and aqueous decoctions of emblica officinalis (amla) and coriandrum sativum (coriander) against 345 bacterial isolates belonging to 6 different genera of gram negative bacterial population isolated from urine specimens by employing well diffusion technique. aqueous infusion and decoction of emblica officinalis exhibited potent antibacterial activity against escherichia coli (270), klebsiella pneumoniae (51), k. ozae ...	2007	17337425
efficacy of a silicone urinary catheter impregnated with chlorhexidine and triclosan against colonization with proteus mirabilis and other uropathogens.	we sought to develop an infection-resistant urinary catheter. we evaluated 3 types of catheters for their efficacy against uropathogens in an in vitro model of the urinary tract. the catheter impregnated with chlorhexidine and triclosan suppressed the growth of uropathogens, including proteus mirabilis, for 20-30 days or longer.	2007	17464922
linear cowden nevus: a new distinct epidermal nevus.	within the group of epidermal nevi, a so far nameless disorder is described under the term "linear cowden nevus". this non-organoid epidermal nevus is caused by loss of heterozygosity, occurring at an early developmental stage in an embryo with a germline pten mutation, giving rise to cowden disease. hence, linear cowden nevus can be categorized as a characteristic feature of type 2 segmental cowden disease. until now, several authors had mistaken this epidermal nevus as a manifestation of prote ...	2007	17337396
bacteriological study of pyogenic meningitis with special reference to latex agglutination.	bacterial meningitis is an important and frequent devastating disease. the present study was carried out to determine the prevalence of pyogenic meningitis in our hospital in children and to find out the sensitivity of gram stain, crp and latex agglutination tests for the diagnosis of pyogenic meningitis from csf sample. out of 150 csf samples studied, 40 were diagnosed as pyogenic meningitis. h. influenzae was the commonest organism (22.5%), followed by streptococcus pneumoniae 15%, staphylococ ...	2007	17474275
psoas abscess ten years after ipsilateral nephrectomy for pyonephrosis.	pyogenic abscess of the psoas muscle is a rare disease. the authors report a recently observed case which developed 10 years after ipsilateral nephrectomy for pyonephrosis, reviewing the pertinent literature. the culture of the pus extracted only reproduced proteus mirabilis. the relation between psoas abscess and nephrectomy is unclear. to make diagnosis is important to consider this condition in differential diagnosis in presence of fever and flank tenderness in a nephrectomized patient.	2007	17475114
bacterial contamination of ophthalmic solutions used in an extended care facility.	to assess the frequency of contamination of ophthalmic solutions in a long-term care facility and to describe the characteristics of contaminated solutions.	2007	17475711
[incidence and clinical characteristics of symptomatic urinary infections in a geriatric hospital].	objectives and settings: the authors had for aim to study the incidence of symptomatic urinary infections (suti) in elderly patients, to describe their clinical and microbiologic characteristics and first-line treatment in a geriatric hospital with 902 beds: 124 in acute care (acf), 293 in rehabilitation and intermediate-care (ricf), and 485 in long-term-care-facilities (ltcf).	2007	17337143
microbiology of diabetic foot infections in a teaching hospital in malaysia: a retrospective study of 194 cases.	diabetes mellitus is a progressive disease with chronic complications. foot infections are a major complication of diabetes and eventually lead to development of gangrene and lower extremity amputation. the microbiological characteristics of diabetic foot infections have not been extensively studied in malaysia. this study investigated the microbiology of diabetic foot infections and their resistance to antibiotics in patients with diabetic foot infections treated at university of malaya medical ...	2007	17332905
both sulfate-reducing bacteria and enterobacteriaceae take part in marine biocorrosion of carbon steel.	in order to evaluate the part played in biocorrosion by microbial groups other than sulfate-reducing bacteria (srb), we characterized the phylogenetic diversity of a corrosive marine biofilm attached to a harbour pile structure as well as to carbon steel surfaces (coupons) immersed in seawater for increasing time periods (1 and 8 months). we thus experimentally checked corroding abilities of defined species mixtures.	2007	17184331
antimicrobial resistance among uropathogens that cause community-acquired urinary tract infections in antananarivo, madagascar.	urinary tract pathogens obtained from patients in madagascar are becoming increasingly resistant to commonly used antibiotics that are readily available at a low price. this poses a real problem for the treatment of community-acquired urinary tract infections (utis) in madagascar.	2007	17138569
effect of ovotransferrin, protamine sulfate and edta combination on biofilm formation by catheter-associated bacteria.	to determine the effect of a composition comprising ovotransferrin (ot), protamine sulfate (ps) and ethylenediaminetetraacetic acid (edta) on biofilm formation by catheter-associated bacteria.	2007	17309621
proteus mirabilis clinical isolate harbouring a new variant of salmonella genomic island 1 containing the multiple antibiotic resistance region.	a clinical isolate of proteus mirabilis strain 18306, which displayed the multidrug resistance phenotype of salmonella genomic island 1 (sgi1), was examined for the presence of this island including its multiple antibiotic resistance genomic region.	2007	17114173
regulation of flhdc expression in proteus mirabilis.	transposon insertions located 325 and 740 base pairs upstream of the transcriptional start site of the flhdc operon resulted in cells that initiated swarming 1.5h earlier than wild-type and exhibited a 2-2.5-fold greater swarming velocity. these mutants also failed to consolidate (de-differentiate) normally and did not form the characteristic bulls-eye pattern of concentric swarming rings on solid media. the analysis of one mutant (ss-p) with an insertion at -325 revealed that the levels of flhd ...	2007	17320355
evaluating antibiotics for use in medicine using a poloxamer biofilm model.	wound infections, due to biofilms, are a constant problem because of their recalcitrant nature towards antibiotics. appropriate antibiotic selection for the treatment of these biofilm infections is important. the traditional in vitro disc diffusion method for antibiotic selection uses bacterial cultures grown on agar plates. however, the form of bacterial growth on agar is not representative of how bacteria grow in wounds and other tissue sites as here bacteria grow naturally in a biofilm. the a ...	2007	17302978
the xaxab genes encoding a new apoptotic toxin from the insect pathogen xenorhabdus nematophila are present in plant and human pathogens.	xenorhabdus nematophila, a member of the enterobacteriaceae, kills many species of insects by strongly depressing the immune system and colonizing the entire body. a peptide cytotoxin has been purified from x. nematophila broth growth, and the cytolytic effect on insect immunocytes and hemolytic effect on mammalian red blood cells of this toxin have been described (ribeiro, c., vignes, m., and brehélin, m. (2003) j. biol. chem. 278, 3030-3039). we show here that this toxin, xenorhabdus alpha-xen ...	2007	17229739
structure of the o-polysaccharide and serological cross-reactivity of the lipopolysaccharide of providencia alcalifaciens o32 containing n-acetylisomuramic acid.	the o-polysaccharide was obtained by mild acid degradation of the lipopolysaccharide of providencia alcalifaciens o32 and studied by sugar and methylation analyses, solvolysis with triflic acid, 1h and 13c nmr spectroscopy, including two-dimensional 1h,1h cosy, tocsy, roesy, h-detected 1h,13c hsqc and hmbc experiments. it was found that the polysaccharide has a branched tetrasaccharide repeating unit containing 2-acetamido-3-o-[(s)-1-carboxyethyl]-2-deoxy-d-glucose (d-glcnac3slac, n-acetylisomur ...	2007	17182016
antimicrobial photodynamic therapy combined with conventional endodontic treatment to eliminate root canal biofilm infection.	to compare the effectiveness of antimicrobial photodynamic therapy (pdt), standard endodontic treatment and the combined treatment to eliminate bacterial biofilms present in infected root canals.	2007	17066481
are laboratory-based antibiograms reliable to guide the selection of empirical antimicrobial treatment in patients with hospital-acquired infections?	antibiograms are often taken into account to define a rational selection of an empirical antimicrobial therapy for treating patients with hospital-acquired infections. in this study, we performed a paired comparison between the antibiogram constructed with laboratory-based data and that formed with data subjected to prior clinical validation.	2007	17079239
there is a low incidence of recurrent bacteriuria in painful bladder syndrome/interstitial cystitis patients followed longitudinally.	the objective of this paper was to establish whether patients with confirmed painful bladder syndrome/interstitial cystitis (pbs/ic) presenting with symptoms of uti have actual bacteriuria vs a flare of their pbs/ic symptoms. one hundred and six (n = 106) consecutive female patients (mean age 39.8 +/- 14 years) with newly diagnosed ic were identified and followed longitudinally for 24 months. at the initial visit and at all subsequent visits, urinary specimens were obtained by sterile catheteriz ...	2007	17036170
[community-acquired urinary tract infections in 15 to 65 years old female patients in france. susceptibility of e. coli according to history: aforcopi-bio network 2003].	a multicenter study was implemented in order to determine the distribution and antibiotic susceptibility patterns of strains isolated from 15 to 65 year old female patients with community-acquired urinary tract infections.	2007	17258415
the effect of lipopolysaccharide from proteus mirabilis on the level of the stable end metabolic products of nitric oxide in blood platelets.	nitric oxide (()no) plays an important role in a number of physiologic processes. evidence exists that ()no, which stimulates soluble guanylate cyclase and enhances cyclic guanosine monophosphate (cgmp) levels, may inhibit platelet activation. in contrast, during platelet activation induced by different agonists, synthesis of ()no in platelets occurs. in these studies, production of the stable end-products of ()no-nitrite and nitrate (no(x)) in human platelets, stimulated by different doses ...	2007	17160361
three cases of xanthogranulomatous epididymitis caused by e. coli.	xanthogranulomatous epididymitis is an uncommon but benign process, characterized by tissue destruction and the accumulation of abundant foamy macrophages mixed with lymphocytes and plasma cells. the pathogens generally found to cause xanthogranulomatous inflammation have been proteus and e. coli. we identified such a pathogen by sequencing divergent regions of 16s rrna, followed by pathogen-specific-pcr using alr, ipah, ial, and iuc primer pairs in dna microdissected from an h&e stained slide. ...	2007	16762415
rhomboid protease aara mediates quorum-sensing in providencia stuartii by activating tata of the twin-arginine translocase.	the providencia stuartii aara protein is a member of the rhomboid family of intramembrane serine proteases and is required for the production of an unknown quorum-sensing molecule. in a screen to identify rhomboid-encoding genes from proteus mirabilis, tata was identified as a multicopy suppressor and restored extracellular signal production as well as complementing all other phenotypes of a prov. stuartii aara mutant. tata is a component of the twin-arginine translocase (tat) protein secretion ...	2007	17215357
rheumatoid arthritis is linked to proteus--the evidence.	rheumatoid arthritis (ra) is a chronic inflammatory arthritic and potentially disabling condition, mainly affecting women of middle age and having characteristic clinical features. various microbial agents were implicated in the causation of ra. extensive literature based on the results of various genetic, microbiological, molecular, and immunological studies carried out by independent research groups supports the role of proteus mirabilis bacteria in the etiopathogenesis of ra. new diagnostic m ...	2007	17206398
use of boronic acid disk methods to detect the combined expression of plasmid-mediated ampc beta-lactamases and extended-spectrum beta-lactamases in clinical isolates of klebsiella spp., salmonella spp., and proteus mirabilis.	a study using boronic acid (ba), an ampc enzyme inhibitor, was designed to detect the combined expression of plasmid-mediated ampc beta-lactamases (pampcs) and extended-spectrum beta-lactamases (esbls) in bacterial isolates naturally lacking chromosomal ampc genes. a total of 122 klebsiella spp., salmonella spp., and proteus mirabilis isolates producing or nonproducing pampcs and/or esbls were analyzed. detection of genes encoding esbls and ampcs was confirmed by polymerase chain reaction (pcr) ...	2007	17174510
proteus bacteriuria is associated with significant morbidity in spinal cord injury.	retrospective chart review.	2007	17179975
infection of a congenital epidural dermoid cyst secondary to lumbar puncture.		2007	17179297
helicobacter pylori: an underestimated factor in acute anterior uveitis and spondyloarthropathies?	acute anterior uveitis (aau) is the most common form of intraocular inflammation, but its aetiology is still unclear. fifty percent of aau patients are hla-b27-positive, and half of these also have spondyloarthropathies (spa). numerous serological studies have shown elevated levels of serum antibodies to various gram-negative bacteria in hla-b27-positive aau and spa patients. antigenic similarities between these bacteria and host components (hla-b27) have already been shown. still, the mechanism ...	2007	17183194
a comparison of the binding of secretory component to immunoglobulin a (iga) in human colostral s-iga1 and s-iga2.	a detailed investigation of the binding of secretory component to immunoglobulin a (iga) in human secretory iga2 (s-iga2) was made possible by the development of a new method of purifying s-iga1, s-iga2 and free secretory component from human colostrum using thiophilic gel chromatography and chromatography on jacalin-agarose. sodium dodecyl sulphate-polyacrylamide gel electrophoresis of unreduced pure s-iga2 revealed that, unlike in s-iga1, a significant proportion of the secretory component was ...	2007	17156102
a microbial diagnostic microarray technique for the sensitive detection and identification of pathogenic bacteria in a background of nonpathogens.	a major challenge in microbial diagnostics is the parallel detection and identification of low-bundance pathogens within a complex microbial community. in addition, a high specificity providing robust, reliable identification at least at the species level is required. a microbial diagnostic microarray approach, using single nucleotide extension labeling with gyrb as the marker gene, was developed. we present a novel concept applying competitive oligonucleotide probes to improve the specificity o ...	2007	17123456
the elephant man.		2007	21991688
the sensitivities to first-line antibiotic therapy of the common urinary tract bacterial infections detected in urine samples at a hospital in metropolitan kampala (uganda).	urinary tract infections (utis) are among the most common human infections. many urinary tract bacteria are capable of expressing drug resistance. resistant bacteria may be present from the commencement of the infection or may develop during treatment. this study focused on the problem of antibiotic resistance to the first-line drugs that were used to treat patients presenting with urinary tract infections at rubaga hospital in kampala, uganda.	2007	21499486
antimicrobial, wound healing and antioxidant activities of anthocephalus cadamba.	anthocephalus cadamba (roxb.) miq. syn a. chinensis (lamk) a. rich (rubiaceae) is ethnomedicinally widely used in the form of paste by tribe in western ghats for treating skin diseases. in this context, antimicrobial potential of a. cadamba against a wide range of microorganisms was studied. to validate the ethnotherapeutic claims of the plant in skin diseases, wound healing activity was studied, besides antioxidant activity to understand the mechanism of wound healing. the alchoholic and aqueou ...	2007	20161916
investigating nanoscale cellular dynamics with cross-sectional spectral domain phase microscopy.	we report on cross-sectional imaging of dynamic biological specimens using a spectral domain phase microscopy (sdpm) system capable of operating at a line rate of 19 khz. this system combines the time-sensitive capabilities of sdpm with the multi-point acquisition features of related phase-sensitive techniques. the presented phase portraits and b-scan phase images of spontaneously beating embryonic cardiomyocytes and cytoplasmic flow in a. proteus offer insight into the nature and timing of the ...	2007	19547138
harmonically matched grating-based full-field quantitative high-resolution phase microscope for observing dynamics of transparent biological samples.	we have developed a full-field high resolution quantitative phase imaging technique for observing dynamics of transparent biological samples. by using a harmonically matched diffraction grating pair (600 and 1200 lines/mm), we were able to obtain non-trivial phase difference (other than 0 degrees or 180 degrees) between the output ports of the gratings. improving upon our previous design, our current system mitigates astigmatism artifacts and is capable of high resolution imaging. this system al ...	2007	19551112
resin-salve from norway spruce--a potential method to treat infected chronic skin ulcers?	the home-made resin salve from norway spruce is traditionally and widely used in folk medicine to heal various skin infections and wounds in northern finland. we have performed laboratory studies to solve the mechanism of resin salve. the resin salve exhibited a bacteriostatic effect against all tested gram-positive bacteria important in human medicine including methicillin-resistant staphylococcus aureus (mrsa) and vancomycin-resistant enterococcus (vre), but was not effective against gram-nega ...	2007	19356034
studies on antimicrobial activity of perionyx excavatus.	the antimicrobial activity of vermiextract was assessed against four human pathogenic microorganisms. especially strains of proteus species are a prominent cause of urinary tract infection in children. the present investigation deals with particular urinary tract pathogenic organisms like e. coli, proteus, providencia, morganella species. screening was performed by disc diffusion method. the zone of inhibition range from 17 to 19 mm against 1.0x10(8) cells of each culture at 1 mg concentration o ...	2007	19090177
new triazole and triazolothiadiazine derivatives as possible antimicrobial agents.	triazole and triazoles fused with six-membered ring systems are found to possess diverse applications in the fields of medicine, agriculture and industry. the new 1,2,4-triazole and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazine derivatives were synthesized as novel antimicrobial agents. the reaction of 1h-indol-3-acetic acid with thiocarbohydrazide gave the 4-amino-3-mercapto-5-[(1h-indol-3-yl)methyl]-4h-1,2,4-triazole. the reaction of triazole with arylaldehydes in ethanol gave the 4-arylideneamino-3 ...	2008	17499887
prevalence of extended-spectrum beta-lactamases in proteus mirabilis in a taiwanese university hospital, 1999 to 2005: identification of a novel ctx-m enzyme (ctx-m-66).	a total of 1574 nonduplicate proteus mirabilis isolates collected at a taiwanese hospital during 1999 to 2005 were analyzed for production of extended-spectrum beta-lactamases (esbls). forty-four esbl-producing isolates including 22 ctx-m-14, 18 ctx-m-3, 2 ctx-m-24, and 2 ctx-m-66 producers were detected, and the proportion of esbl producers increased from 0.7% in 1999 to approximately 6% after 2002. ctx-m-66 is a novel variant of ctx-m esbls that differs from ctx-m-3 by a ser to asn change at a ...	2008	17913434
diverse tetracycline resistant bacteria and resistance genes from coastal waters of jiaozhou bay.	environmental microbiology investigation was carried out in jiaozhou bay to determine the source and distribution of tetracycline-resistant bacteria and their resistance mechanisms. at least 25 species or the equivalent molecular phylogenetic taxa in 16 genera of resistant bacteria could be identified based on 16s ribosomal deoxyribonucleic acid sequence analysis. enterobacteriaceae, pseudomonadaceae, and vibrionaceae constituted the majority of the typical resistant isolates. indigenous estuari ...	2008	17668262
synthesis, characterization and antibacterial activity of cobalt(iii) complexes with pyridine-amide ligands.	the ligands 2-(n-(x-pyridyl)carbamoyl)pyridine (x=2, 3 or 4 for hl1-hl3, respectively) and 2,6-bis(n-(y-pyridyl)carbamoyl)pyridine (y=2, 3 or 4 for h2l4-h2l6, respectively) in their mono- and di-deprotonated forms have been used to synthesize kinetically stable cobalt(iii) compounds [co(l1-3)3] (1-3) and na[co(l4-6)2] (4-6), respectively. the co(iii) ion is in octahedral environment and is surrounded by three bidentate ligands in complexes 1-3 and two tridentate ligands in complexes 4-6. ligands ...	2008	17959275
in vitro activities of tigecycline combined with other antimicrobials against multiresistant gram-positive and gram-negative pathogens.	to test the activity of tigecycline combined with 16 antimicrobials in vitro against 22 gram-positive and 55 gram-negative clinical isolates.	2008	18033780
endoscopic treatment of pituitary abscess: two case reports and literature review.	pituitary abscess is a rare entity and the correct diagnosis is still difficult before surgery. more than 210 cases have been reported in the medical literature, mostly in the form of isolated case reports. we report two cases of pituitary abscess treated endoscopically and we review the literature. a 30-year-old woman and a 35-year-old man were admitted with a history of pituitary dysfunction. patient 1 presented with polyuria, polydipsia, amenorrhea, headache, and visual impairment. magnetic r ...	2008	17899232
rheumatoid arthritis in smokers could be linked to proteus urinary tract infections.	there is an interplay between genetic and environmental factors in the induction and development of rheumatoid arthritis (ra). the ra-associated hla-drb1 alleles which contain the shared epitope moiety as well as microbial triggers such as proteus are involved in the aetiopathogenesis of this disease. increased association between proteus urinary tract infections (utis) and ra on one hand and the link between smoking and utis on the other hand could explain the increased frequency of ra among sm ...	2008	17983708
in vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds.	against 182 anaerobe and 241 aerobe strains obtained from diabetic foot infections, doripenem was the most active carbapenem against pseudomonas aeruginosa (mic(90), 2 microg/ml), more active than imipenem against proteus mirabilis, and ertapenem was more active against escherichia coli and klebsiella spp. the mic(50) and mic(90) values were < or =0.125 microg/ml for methicillin-sensitive staphylococcus aureus and all streptococci and 0.25/1 for bacteroides fragilis.	2008	18070958
isolation and purification of enterocin e-760 with broad antimicrobial activity against gram-positive and gram-negative bacteria.	strain nrrl b-30745, isolated from chicken ceca and identified as enterococcus durans, enterococcus faecium, or enterococcus hirae, was initially identified as antagonistic to campylobacter jejuni. the isolate produced a 5,362-da bacteriocin (enterocin) that inhibits the growth of salmonella enterica serovar enteritidis, s. enterica serovar choleraesuis, s. enterica serovar typhimurium, s. enterica serovar gallinarum, escherichia coli o157:h7, yersinia enterocolitica, citrobacter freundii, klebs ...	2008	18086839
presence of aquaporin and v-atpase on the contractile vacuole of amoeba proteus.	the results of water permeability measurements suggest the presence of an aqp (aquaporin) in the membrane of the cv (contractile vacuole) in amoeba proteus [nishihara, shimmen and sonobe (2004) cell struct. funct. 29, 85-90].	2008	18004980
rmtc 16s rrna methyltransferase in australia.		2008	18025117
type 2 segmental cowden disease vs. proteus syndrome: reply from authors.		2008	17999697
activities of the frog skin peptide, ascaphin-8 and its lysine-substituted analogs against clinical isolates of extended-spectrum beta-lactamase (esbl) producing bacteria.	extended-spectrum beta-lactamase (esbl)-producing gram-negative bacteria are becoming increasingly prevalent and their antibiotic resistance necessitates novel therapeutic intervention. ascaphin-8 is a cationic alpha-helical peptide that shows broad-spectrum antibacterial activity but is also toxic to human erythrocytes (lc(50)= 55 microm). this study assesses the activity of ascaphin-8, and a series of l-lysine-substituted analogs, against a range of clinical isolates of esbl-producing bacteria ...	2008	18068868
structure and mode of action of the antimicrobial peptide arenicin.	the solution structure and the mode of action of arenicin isoform 1, an antimicrobial peptide with a unique 18-residue loop structure, from the lugworm arenicola marina were elucidated here. arenicin folds into a two-stranded antiparallel beta-sheet. it exhibits high antibacterial activity at 37 and 4 degrees c against gram-negative bacteria, including polymyxin b-resistant proteus mirabilis. bacterial killing occurs within minutes and is accompanied by membrane permeabilization, membrane detach ...	2008	17935487
microbial keratitis in a case of lamellar ichthyosis.	we report a case of microbial keratitis in a patient with lamellar ichthyosis. an 11-year-old boy, a known case of lamellar ichthyosis, presented with microbial keratitis. microbiological evaluation of corneal scraping revealed a mixed infection caused by gram-negative bacilli and gram-positive cocci. he was treated with topical ciprofloxacin and fortified cefazolin eyedrops. microbial keratitis in patients with lamellar ichthyosis has a poor prognosis.	2008	17828596
design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases.	a new group of organophosphorus inhibitors of urease, p-methyl phosphinic acids was discovered by using the structure based inhibitor design approach. several derivatives of the lead compound, aminomethyl(p-methyl)phosphinic acid, were synthesized successfully. their potency was evaluated in vitro against urease from bacillus pasteurii and proteus vulgaris. the studied compounds constitute a group of competitive, reversible inhibitors of bacterial ureases. obtained thiophosphinic analogues of th ...	2008	18717581
prevalence of quinolone-resistant urinary tract infections in comanche county memorial hospital.	urinary tract infection (uti) is not only a common outpatient but also the most frequently occurring nosocomial infection. the most common causative organisms of uti remain escherichia coli, nosocomial gram-negative bacilli, enteroccoci and candida. many physicians use quinolones as the agent of choice for treatment of uti. as calculated by the drug utilization data of 2007, the rate of quinolone use by physicians for uti is 48%. this study was performed to determine the prevalence of quinolone- ...	2008	18856050
inhibition of candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge dysidea sp.	seven sesterterpene sulfates (1-7) were isolated from the tropical sponge dysidea sp. and their inhibitory activities against isocitrate lyase (icl) from candida albicans were evaluated. among the isolated natural products compound 6 and 7 were found to be strong icl inhibitors. the isolated compounds (1-7) also showed potent antibacterial effect against bacillus subtilis and proteus vulgaris, but did not display antifungal activity.	2008	18824352
determination of pathogenic bacteria by cze with surface-modified capillaries.	the importance of electromigration techniques in molecular biology and medicine is increasing rapidly, especially in systematic studies on proteomes and metabolomes. staphylococcus aureus and escherichia coli are bacterial species most frequently encountered in human infections, and many serious illnesses can be observed in the hospital environment. in this contribution we proposed a ce method with different modification of internal capillary surface and with monolithic beds as a selective mater ...	2008	18942676
bacteriology of non-surgical wound infections in ibadan, nigeria.	previous studies done on wound infections in this environment had been mostly on the surgical variety rather than the non-surgical. however,few studies available on the non-surgical type have indicated that changes do occur in the pattern and antibiogram of the bacterial isolates of these non-surgical wound infections. this study was therefore designed to investigate the bacteriology of non-surgical wound infections in this environment. a retrospective review of seven hundred and fifty four case ...	2008	18982819
genetic and phenotypic heterogeneity in the pten hamartoma tumour syndrome.	germline pten (phosphatase and tensin homologue deleted on chromosome ten) mutations predispose to phenotypically diverse disorders that share several overlapping clinical features: cowden syndrome, bannayan-riley-ruvalcaba syndrome, proteus syndrome and proteus-like syndrome, collectively classified as pten hamartoma tumour syndrome (phts). the meticulous acquisition and documentation of phts phenotypic data at different levels and the profiling of the plethora of genetic changes in pten and ot ...	2008	18794875
[macrodactylies of the hand and foot].	macrodactyly is a rare congenital anomaly defined by an enlargement of all the structures of fingers or toes. two forms of macrodactyly have been described. one form is static with an enlargement present at birth and growing proportionately to the other digits. the other is progressive with an enlargement beginning in early childhood and growing faster than that of the normal digits. macrodactyly is responsible of a functional handicap and an aesthetic prejudice. treatment may be indicated for t ...	2008	18842439
uropathogens and host characteristics.	uropathogens other than escherichia coli occur with greater frequency in patients with risk factors for urinary tract infection (uti). however, little is known about associations between uropathogen species and host characteristics. three hundred nineteen urine specimens containing a balanced distribution of uropathogen species were selected from inpatients and outpatients at a university hospital clinical microbiology laboratory. information on host characteristics was retrospectively collected ...	2008	18842936
nationwide surveillance in taiwan of the in-vitro activity of tigecycline against clinical isolates of extended-spectrum beta-lactamase-producing enterobacteriaceae.	tigecycline in-vitro surveillance in taiwan (tist), initiated in 2006, is a nationwide surveillance programme designed to monitor longitudinally the in-vitro activity of tigecycline against commonly encountered resistant bacteria. this study compared the in-vitro activity of tigecycline against clinical isolates of resistant gram-negative bacteria determined by the broth microdilution and etest methods. a total of 622 isolates were collected from patients treated at 20 teaching hospitals. tigecy ...	2008	19013351
[nationwide susceptibility surveillance of ciprofloxacin and various parenteral antimicrobials against bacteria isolated from patients with severe infections--third ciproxan injection special survey (2005)].	we conducted 3 nationwide surveillance studies between 2001 and 2005 at 39 participating institutions throughout japan according to the special survey plan to investigate susceptibility to ciprofloxacin (cpfx) and various parenteral antimicrobials using clinical isolates from patients with severe infection during the reexamination period of parenteral cpfx. results of the first special survey (2001) were already reported in this journal. the current third special survey (2005) was conducted at 3 ...	2008	19024645
bacterial biofilms in patients with indwelling urinary catheters.	bacteria have a basic survival strategy: to colonize surfaces and grow as biofilm communities embedded in a gel-like polysaccharide matrix. the catheterized urinary tract provides ideal conditions for the development of enormous biofilm populations. many bacterial species colonize indwelling catheters as biofilms, inducing complications in patients' care. the most troublesome complications are the crystalline biofilms that can occlude the catheter lumen and trigger episodes of pyelonephritis and ...	2008	18852707
[antagonistic properties of enterococci isolated from gastrointestinal tract of long-livers].	the strains with antagonistic activity against indicator strains pseudomonas aeruginosa, proteus vulgaris, staphylococcus aureus, staphylococcus epidermidis, escherichia coli, klebsiella pneumonia, salmonella enterica were revealed among 58 enterococcus strains isolated from gastrointestinal tract of long-livers. the influence of different components of mrs medium on the antagonistic effect was established. antagonistic activity remained on the medium without glucose in 36% of strains, on the me ...	2008	19044009
experimental and qsar of acetophenones as antibacterial agents.	antibacterial activity of 20 acetophenone derivatives was evaluated against two gram-positive and three gram-negative organisms, namely, bacillus subtilis ncim 2718, staphylococcus aureus ncim5021, salmonella typhi ncim2501, enterobacter aerogenes ncim5139, and proteus vulgaris ncim2813 by two-fold dilution method. the most active amongst this group of compounds were 4-methyl, 2-hydroxy, 3-bromo, 4-ethoxy, 3-nitro and 4-nitro acetophenones. quantitative structure-activity relationships were deve ...	2008	18844677
hemihyperplasia-multiple lipomatosis syndrome (hhml): a challenge in spinal care.	a 15-year-old girl developed a progressive paraparesis over a period of six months, secondary to spinal cord compression by a lipomatous mass and anomalies of the vertebral column. clinically, a right hemihyperplasia affecting the trunk and lower limb was evident, as well as a right convex lumbar scoliosis. ct and mri demonstrated severe spinal cord compression resulting from intraspinal lipomatosis, overgrowth of right facet joints (t8 to l5), and kyphoscoliosis. surgical decompression was unde ...	2008	19058713
changing trend in antimicrobial resistance of pediatric uropathogens in taiwan.	there is growing concern regarding antimicrobial resistance worldwide, particularly of escherichia coli, and the first choice of an antimicrobial agent for empiric treatment of pediatric urinary tract infection (uti) is not well established.	2008	19067894
[recent evolution and characterization of extended-spectrum beta-lactamase producing enterobacteria in the chu of nice (2005-2007)].	esbl producing enterobacteria (e-esbl+) are always a public health concern, mainly due to increase of ctx-m beta-lactamase. so, 542 new strains were isolated in the chu de nice during the 2005-2007 period. the aim of this work was to characterize the esbl and to type isolates suspected to be implicated in outbreaks.	2008	18848404
[purple urine bag syndrome].		2008	18922671
antimicrobial activities of pomegranate rind extracts: enhancement by addition of metal salts and vitamin c.	punica granatum l. or pomegranates, have been reported to have antimicrobial activity against a range of gram positive and negative bacteria. pomegranate formulations containing ferrous salts have enhanced although short-term, antibacteriophage activities which are rapidly diminished owing to instability of the ferrous combination. the aim of this study was to determine the antimicrobial activities of combinations of pomegranate rind extracts (pre) with a range of metals salts with the added sta ...	2008	19077299
purple like a glove.		2008	18951389
outer membrane antigens of the uropathogen proteus mirabilis recognized by the humoral response during experimental murine urinary tract infection.	proteus mirabilis, a gram-negative bacterium, is a frequent cause of complicated urinary tract infections in those with functional or anatomical abnormalities or those subject to long-term catheterization. to systematically identify surface-exposed antigens as potential vaccine candidates, proteins in the outer membrane fraction of bacteria were separated by two-dimensional gel electrophoresis and subjected to western blotting with sera from mice experimentally infected with p. mirabilis. protei ...	2008	18625734
antibacterial activity of halogenated sesquiterpenes from malaysian laurencia spp.	during our studies on malaysian laurencia species, brominated metabolites, tiomanene, acetylmajapolene b, and acetylmajapolene a were isolated from an unrecorded species collected at pulau tioman, pahang along with known majapolene b and majapolene a. acetylmajapolene a was a mixture of diastereomers as in the case of majapolene a. tiomanene may be a plausible precursor for acetylmajapolenes b and a. in addition, three known halogenated sesquiterpenes and two known halogenated c(15) acetogenins ...	2008	18718619
identification of virulence determinants in uropathogenic proteus mirabilis using signature-tagged mutagenesis.	the gram-negative bacterium proteus mirabilis causes urinary tract infections (utis) in individuals with long-term indwelling catheters or those with functional or structural abnormalities of the urinary tract. known virulence factors include urease, haemolysin, fimbriae, flagella, dsba, a phosphate transporter and genes involved in cell-wall synthesis and metabolism, many of which have been identified using the technique of signature-tagged mutagenesis (stm). to identify additional virulence de ...	2008	18719175
antibacterial properties of fish mucus from channa punctatus and cirrhinus mrigala.	extracts and preparations made from the animal origin were used extensively in folk and modern medicine for treating many human diseases. in the present study efforts have been made to find the antimicrobial effect of the mucus of two bottom dwelling fresh water fishes namely, channa punctatus and cirrhinus mrigala. fish mucus were tested against ten pathogenic bacteria such as escherichia coli, klebsiella oxytoca, klebsiella pneumoniae, lactobacillus vulgaris, proteus mirabilis, pseudomonas aer ...	2008	18700685
prevalence and beta-lactamase producing bacterial isolates in a teaching hospital in peshawar, pakistan: a four year study.	prevalence of microorganisms was studies in clinical samples of various body fluids (n=12,259), collected from patients at post graduate medical institute hayatabad medical complex (pgmi, hmc) peshawar. only 34.90% of samples exhibited growth, 36.25% of these isolates were gram positive and 63.75% were gram negative bacteria. e. coli was the most prevalent organism (39.45%) followed by s. aureus (32.23%), proteus spp. (9.23%), pseudomonas spp. (6.54%), streptococuss spp. (3.51%), acinetobacter s ...	2008	18930859
flavonoids from pterocaulon alopecuroides with antibacterial activity.	three flavonoids, (2 r,3 r)-5,4'-dihydroxy-3'- o-methyl-7-(gamma,gamma-dimethylallyloxy)dihydroflavonol 1, (2 r,3 r)-5,7,4'-trihydroxy-3'- o-methyl-6-(alpha,alpha-dimethylallyl)dihydroflavonol 2, and (2 r,3 r)-5,7,4'-trihydroxy-6-(alpha,alpha-dimethylallyl)dihydroflavonol 3, together with three known flavonoids ( 4 - 6), were isolated from the aerial parts of pterocaulon alopecuroides. the structures of the compounds were determined by mass and by 1 d and 2 d nmr spectroscopy. screening of the a ...	2008	18704884
detection of protozoan and bacterial pathogens of public health importance in faeces of corvus spp. (large-billed crow).	parasites and bacteria are reported in the faeces of birds in the current study. fresh faecal samples of the large-billed crow (corvus spp.) were collected from the study site at bangsar, an urban setting in kuala lumpur, malaysia. these samples were transported to laboratory and analysed for parasites and bacteria. pre-prepared xld agar plates were used for culturing the bacteria in the laboratory. using the api 20etm test strips, 9 different species of bacteria were identified belonging to the ...	2008	18948884
[antimicrobial resistance of uropathogens among outpatients, 2000-2004].	a retrospective study based on the electronic database of a university hospital was carried out to investigate the prevalence of etiological agents and their susceptibilities to antibiotics, among adult outpatients (> 18 years old) with urinary tract infections. nine hundred and fifty-seven positive urine cultures were identified between january 2000 and december 2004. escherichia coli, proteus mirabilis and klebsiella sp were the three principal bacterial etiological agents. trimethoprim-sulfam ...	2008	18719808
non-susceptibility trends among enterobacteriaceae from bacteraemias in the uk and ireland, 2001-06.	enterobacteriaceae are common agents of bacteraemia, with escherichia coli accounting for 20% of the cases. reflecting this importance, members of the family constitute 4 of the 12 collection groups in the british society for antimicrobial chemotherapy (bsac) bacteraemia surveillance programme.	2008	18819979
purple urine bag syndrome.		2008	18725621
[lower urinary tract infections: bacterial epidemiology and recommendations].	lower urinary tract infection remains frequent particularly in women, despite improvement in therapeutic means. it seems likely to revisit bacterial epidemiology and therapeutic available strategies. to analyze elements in presence i.e. infecting bacteria and antibiotics still active or identification of acquired resistance mechanisms should permit to establish the evolution during the last 10 years. the study shows that bacterial epidemiology in urinary tract infection has not changed significa ...	2008	18773847
highly resistant microorganisms in a teaching hospital: the role of horizontal spread in a setting of endemicity.	to determine the incidence density of highly resistant organisms (hros) and the relative contribution of horizontal spread in a setting of endemicity.	2008	18973456
dna adenine methylation of sams1 gene in symbiont-bearing amoeba proteus.	the expression of amoeba sams genes is switched from sams1 to sams2 when amoebae are infected with legionella jeonii. to elucidate the mechanism for the inactivation of host sams1 gene by endosymbiotic bacteria, methylation states of the sams1 gene of d and xd amoebae was compared in this study. the sams1 gene of amoebae was methylated at an internal adenine residue of gatc site in symbiont-bearing xd amoebae but not in symbiont-free d amoebae, suggesting that the modification might have caused ...	2008	18974959