Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| polyamines in trichomonas vaginalis. | trichomonas vaginalis was grown in a modified bushby's medium and putrescine, spermidine and spermine levels were determined in extracts from 24- and 48-h cultures and also in the culture media. all three polyamines were present in t. vaginalis extracts; the putrescine level and putrescine/spermidine ratio were much higher than those reported for other protozoa or for mammalian tissues. there were no significant differences between 24-h and 48-h amine levels per mg protein in these extracts, but ... | 1983 | 6606778 |
| proceedings of the international symposium on trichomonadosis. bialystok, 13-15 july 1981. | 1983 | 6606905 | |
| [changes in trichomonas vaginalis sensitivity to metronidazole]. | 1983 | 6606994 | |
| metabolism and metronidazole uptake in trichomonas vaginalis isolates with different metronidazole susceptibilities. | three trichomonas vaginalis isolates with low in vivo susceptibilities to metronidazole (95% curative dose, greater than 3 x 100 mg kg-1 in subcutaneous infections in mice) were compared with strain atcc 30001 and with four isolates exhibiting high in vivo susceptibilities (95% curative dose, less than 3 x 15 mg kg-1). activity of pyruvate:ferredoxin oxidoreductase, anaerobic fermentation, and anaerobic intracellular accumulation of [14c]metronidazole label showed no significant isolate-dependen ... | 1983 | 6607028 |
| bacterial and fungal growth in urinary trichomoniasis. | 1983 | 6607296 | |
| microbial flora in women showing symptoms of nonspecific vaginosis: applicability of koh test for diagnosis. | the microbial flora of the vagina in 100 consecutive patients coming to a gynaecologist's office because of excessive and malodourous vaginal discharge was investigated. anaerobic bacteria were detected in 66% of cases, and gardnerella vaginalis in 59% of cases. lactobacilli were present in 52% of cases, candida in 19%, chlamydia trachomatis in 6% and trichomonas vaginalis in 5%. among the anaerobic bacteria, various strains of bacteroides or fusobacteria were the most common. the positive predi ... | 1983 | 6607523 |
| [antimicrobial action of a vaginal solution containing miconazole]. | 1983 | 6396580 | |
| [vaginal candidiasis and trichomonas. can they be diagnosed clinically with certainty?]. | 1983 | 6398785 | |
| unsuspected chlamydia trachomatis in females attending a sexually transmitted diseases clinic. | one hundred and five women attending auckland sexually transmitted diseases clinic were reviewed because of positive cervical cultures for chlamydia trachomatis. their average age was 19 years, 70% were european; 28% were maori. in half the patients the positive culture was a chance finding and therefore treatment was delayed resulting in six patients (12%) developing pelvic inflammatory disease. eight out of nine male contacts, subsequently traced, had asymptomatic urethritis, one having epidid ... | 1983 | 6577348 |
| haemophilus influenzae in genitourinary tract infections. | haemophilus influenzae was isolated in pure or predominant culture from genital specimens from nine females and two males. four of the females had vaginitis, two had iud-related endometritis, one had an incomplete septic abortion, and one had probable urethral syndrome. two males had urethritis. | 1983 | 6608436 |
| trichomonas infection in pregnancy--does it affect perinatal outcome? | antenatal patients free of trichomonas vaginalis vaginal infection were compared with infected patients, half of whom were treated and half left untreated. the treated group was given benzoylmetronidazole 50 ml (2 g metronidazole equivalent) as a single dose. the mode of treatment was found to be very palatable and highly effective. the birth weights and gestational age at delivery were similar in all three groups. | 1983 | 6845046 |
| [preventive gynecological examinations of women employed in the cement industry]. | prophylactic gynecologic examinations were carried out in 218 women-workers of a cement plant. the most frequent diseases were: retroflexion of the uterus (55.5%), inflammation of the ovary (50.45%), erosion of the vaginal part of the uterus (41.8%), prolapse of the vaginal walls (39.45%), incontinence (35.32%) and trichomonas vaginalis (18.7%). the extensive prevalence of the diseases imposes a need to carry on preventive examinations of women employed in cement industry. the authors indicate t ... | 1983 | 6865741 |
| short-term treatment of trichomonas vaginalis with tioconazole cream, a new antifungal agent. | 1983 | 6873746 | |
| antibiotic a 19009. structural investigation and synthesis. | the structure of fermentation product a 19009 was reinvestigated by 13c and 1h nmr spectroscopy and established by independent synthesis to be n2-l-alanyl-n3-fumaramoyl-l-2,3-diaminopropanoic acid (2), i.e. a structure isomeric with the originally proposed structure 1. in contrast to 1 which also was synthesized, 2 has a very low activity against trichomonas vaginalis. | 1983 | 6885634 |
| differential effects of inhibitors of purine metabolism on two trichomonad species. | tritrichomonas foetus and trichomonas vaginalis are both incapable of de novo purine nucleotide synthesis. previous studies indicated that t. foetus relies mainly on the salvage of hypoxanthine and subsequent conversion of imp to amp and gmp, whereas t. vaginalis depends on direct conversions of exogenous adenosine to amp and guanosine to gmp without much interconversion between the two nucleotides. these two different types of purine salvage suggest the possibility of differential sensitivities ... | 1984 | 6608946 |
| [gas chromatographic studies on propionic acid, butyric acid and valeric acid in culture fluid of trichomonas vaginalis]. | trichomonas vaginalis was inoculated into cysteine-peptone-liver infusion-maltose medium (cplm medium), and serial changes in short-chain fatty acids in the culture fluid were studied by gas chromatography. a significant increase in the amount of propionic acid and iso-valeric acid was found in the culture fluids obtained at 72 or 120 hours after inoculation of trichomonas vaginalis. these short-chain fatty acids are considered to be produced in vitro during the growth of trichomonas vaginalis i ... | 1984 | 6609217 |
| comparison of virulence of clones of two trichomonas vaginalis strains by the subcutaneous mouse assay. | no statistical differences in virulence were found among five clones isolated from each of two trichomonas vaginalis strains jh31a and balt 42. the former strain, isolated from a patient showing no cervical epithelial abnormalities, caused relatively small subcutaneous lesions in mice [mean volume for the noncloned strain, 75.45 +/- 4.43 mm3 (n = 70); mean of means for cloned populations, 77.28 +/- 3.14 mm3 (n = 230)]. the latter, balt 42, isolated from a woman with an in situ carcinoma of the c ... | 1984 | 6609494 |
| [treatment of vulvovaginitis in children and adolescents with metronidazole]. | vulvovaginitis is the most observed genital disease in children and adolescents and dependent from different etiologic factors. bacteriogenic non specific infections were the most frequent cause in 275 girls. bacteria were evident in 77.5 per cent, monilia, in 12.7 per cent and trichomonas vaginalis in 3.3 per cent. 143 cases were treated with metronidazole. all patients with trichomoniasis vaginitis became free of trichomonads. the cure rate of the anaerobic infections was 73.1 per cent. no sid ... | 1984 | 6609502 |
| enzyme linked immunosorbent assay for detecting antibody to trichomonas vaginalis: use of whole cells and aqueous extract as antigen. | an enzyme linked immunosorbent assay (elisa) for detecting antibody to antigenic trichomonas vaginalis macromolecules has been identified using whole cells or an aqueous protein extract as antigen. the test was developed under optimum conditions using serum samples from experimental animals. the sensitivity of the elisa was equal to or greater than that obtained by radioimmunoprecipitation and electrophoresis-fluorography techniques. the elisa was capable of assessing antibody responses during t ... | 1984 | 6610453 |
| a freeze-fracture electron microscope study of trichomonas vaginalis donné and tritrichomonas foetus (riedmüller). | two strains of trichomonas vaginalis, jh162a , with low pathogenicity, and balt 44, with high pathogenicity, as well as one highly pathogenic strain, kv-1, of tritrichomonas foetus were studied by freeze-fracture electron microscopy. the protoplasmic faces ( pfs ) of the cell membranes of all three strains of both species had similar numbers of intramembranous particles (imps); however, the particles in the external faces (efs) of these membranes were least abundant in trichomonas vaginalis stra ... | 1984 | 6610746 |
| nonsexual transmission of sexually transmitted diseases: an infrequent occurrence. | sexually transmitted diseases occur in epidemic numbers in the united states today. nonsexual transmission of these diseases is rarely an issue in adults. however, when the same diseases are found in children, the tendency of pediatricians and other health care practitioners has been to believe the mode of transmission is asexual. a review of gonorrhea, chlamydia trachomatis, herpes genitalis, condyloma acuminata, trichomonas vaginalis, syphilis, chancroid, and granuloma inguinale infections has ... | 1984 | 6610855 |
| observations of trichomonas vaginalis infections at the university teaching hospital in calabar, nigeria. | the pattern of trichomonas vaginalis infections at the outpatient clinic of the university teaching hospital in calabar, nigeria was determined for the two-year period (january 1981 - december 1982). of the 5520 patients examined in 1981, t. vaginalis was found in 10 males (0.11%) and 57 females (1.03%). of the 2511 patients examined in 1982, the parasite was found in 27 males (1.07%) and 31 females (1.20%). a few prepubertal cases were observed. the increasing significance of t. vaginalis as a ... | 1984 | 6611622 |
| relationship between contraceptive method and vaginal flora. | this study was undertaken to assess whether the vaginal flora was affected by the method of contraception, and in particular as to whether the incidence of vaginal candidiasis increased when oral contraceptives were used. one thousand and two consecutive vaginal or cervical swabs from women attending a family planning centre were cultured. candida albicans was isolated from 13% of women using no contraception, 16% using oral contraceptives, and from 9%, 19% and 18% of those using diaphragms, int ... | 1984 | 6596089 |
| double-blind comparative study of trichomonas vaginalis infection: solcotrichovac versus placebo. | 1984 | 6399488 | |
| [the laboratory and colposcopy in the diagnosis of urogenital trichomoniasis]. | urogenital trichomoniasis is a very common condition, the most frequent veneral disease in women. it is also the commonest cause of vaginal discharge. nevertheless, it is often unrecognised since attenuated, latent, unusual forms are more numerous than acute forms which might lead to a suspicion of the diagnosis, and because the investigations which are necessary to make the diagnosis are not made often enough. two types of investigation are available: laboratory studies to seek the parasite and ... | 1984 | 6397829 |
| growth of candida species in liquid culture medium for trichomonas vaginalis. | the growth of candida spp from vaginal specimens in bushby's liquid medium for t vaginalis was compared with that on sabouraud's agar medium, and isolation was significantly greater in bushby's medium (p less than 0.001). isolations missed (4.43%) in bushby's medium probably represented vaginal carriage of small numbers of candida spp. | 1984 | 6607763 |
| pathogenic trichomonas vaginalis cytotoxicity to cell culture monolayers. | exposure of monolayer cultures of human urogenital and vaginal (hela), human epithelial (hep-2), normal baboon testicular (nbt), and monkey kidney (vero) cells to live pathogenic trichomonas vaginalis resulted in extensive disruption of monolayers. trypan blue was taken up by all host cells released from cell monolayers, which indicated irreversible damage of these cell types by trichomonads. time and dose related data on cytotoxicity kinetics were obtained using increasing ratios of parasites t ... | 1984 | 6608395 |
| interaction between trichomonas vaginalis and other pathogenic micro-organisms of the human genital tract. | trichomonas vaginalis organisms were mixed with suspensions of neisseria gonorrhoeae, mycoplasma hominis or chlamydia trachomatis to allow ingestion of these micro-organisms by the trichomonads. culture studies indicated that gonococci and mycoplasmas were ingested and that the number of intracellular viable organisms decreased rapidly, most gonococci being killed within six hours and all mycoplasmas within three hours. electron microscopy revealed phagocytic uptake and destruction of these two ... | 1984 | 6421451 |
| [gonococcal infections in gabon (haut-ogooué)]. | the isolation of n. gonorrhoeae in the region of franceville was attempted on the one hand with 261 men and 261 women presenting urethral or cervical discharge, and on the other hand with 530 women attending a prenatal clinic of whom 42 had cervical discharge while 488 did not. amongst the men, 69.7% of the urethritis cases were due to n. gonorrhoeae while this bacteria could be isolated from 15.3% of the women with cervical exudates. n. gonorrhoeae could be also identified in 5.5% of the pregna ... | 1984 | 6422430 |
| purine salvage enzymes in leishmania donovani and trichomonas vaginalis. | 1984 | 6426255 | |
| can trichomonas vaginalis cause pneumonia in newborn babies? | 1984 | 6432096 | |
| motile curved rods in women attending a std clinic. | motile anaerobic curved rods were cultured from vaginal discharge of 19 of 262 women attending an std clinic. in 26 women, motile rods were observed by examination of wet smears. in all 5 specimens culture-positive for motile anaerobic curved rods of the long type, motile rods were observed in the wet smears, while in only 6 of the 14 specimens culture-positive for motile anaerobic curved rods of the short type, were motile rods seen in wet smears. | 1984 | 6443163 |
| the relation between trichomonas vaginalis and contraceptive measures. | the relationship between the incidence of trichomonas vaginalis and the use of oral contraceptive (oc) pills was observed in 100 females from the outpatient clinic of cairo university hospital. 50 patients took the oc anovlar and 50 used a size 3 lippes loop. 2 sample discharges were analyzed before contraceptive use, i.e. 1 wet smear on a clean slide and the other cultured on trichosol trypticase serum medium (sts) composed of trypticase 20 gm, cysteine hcl 1 1/2 gm, maltose 1 gm, agar 1 gm, me ... | 1984 | 6512296 |
| [actinomyces-like organisms in users of intrauterine contraception]. | actinomyces-like organisms (alo) were found in 6.9% of cervical smears in 2133 iud users. the chance of having co-infection with trichomonas vaginalis was 2.7 times higher in women with alo than in alo negative women. the proportion of iud users with alo in cervical smears increased with the duration of the iud use. a total of 108 iud users with alo were compared with the same number of iud users without alo in cervical smears. the women in the two groups were matched for the duration of the iud ... | 1984 | 6535891 |
| sexually transmitted diseases: an epidemic in adolescent girls? | the prevalence of sexually transmitted disease (std) in adolescent girls aged 15-19 attending a department of genitourinary medicine was compared for the years 1972 and 1982. data were obtained from the confidential register using the coding of the clinic returns to the department of health (form sbh 60). there were 1373 patients in 1972 and 1799 in 1982, 6.4% and 7% respectively of the total female clinic population. the prevalence of syphilis, gonorrhoea, and infection with trichomonas vaginal ... | 1984 | 6549148 |
| infectious involvements in males with reiter's syndrome. | to obtain data on infectious involvements contributing to joint attacks in reiter's syndrome (rs) 72 consecutive males with rs were investigated. controls were 219 personally interviewed males. a history of some type of oro-naso-pharyngeal or pulmonary infectious involvements were reported as often in the patients as in the controls, but the frequency of persons with a history of joint manifestations followed by these infections was significantly higher in the patients (23/72) than in the contro ... | 1984 | 6549275 |
| [vagino-cytological studies in prostitutes]. | numerous papers on the high incidence of precancerous lesions of the uterine cervix in prostitutes have been published mainly in anglo-american literature. the reported data were compared with those of prostitutes in a south german city. in a retrospective study on 239 prostitutes and a control group of 502 patients of the same age distribution the data regarding the vaginal flora and the obtained cytologic groups (modified papanicolaou classification "m unchner nomenklatur ") were compared. the ... | 1984 | 6562985 |
| [diagnosis, clinical aspects and therapy of vulvovaginitis in daily medical practice]. | 1984 | 6371989 | |
| on the causation of pelvic inflammatory disease. | the classic descriptive model of pelvic inflammatory disease (pid) omits any direct statement that sexual intercourse leads to the development of the lower genital or cervical infection which ultimately leads to upper genital or tubal infection. despite this, clinicians treating patients with pid frequently, either implicity or explicitly, link its onset to sexual activity. in the past decade numerous authors have commented on the strong association between the widespread changes in sexual at ... | 1984 | 6372489 |
| isolation of gardnerella vaginalis from routine genito-urinary tract specimens. | routine screening of 2374 high vaginal swabs yielded 132 cultures (5.6 per cent) which were positive for gardnerella vaginalis. thirty-four of the strains were isolated together with candida albicans and 46 with trichomonas vaginalis. one hundred and twenty (90.9 per cent) of the isolates were from females between the ages of 16 and 40 years. one hundred and nineteen (90 per cent) patients sought medical advice because of a history of discharge (88) or inflammation (31). the other 13 (10 per cen ... | 1984 | 6373950 |
| pathogenicity of trichomonas vaginalis: cytopathologic and histopathologic changes of the cervical epithelium. | virulence of 52 trichomonas vaginalis isolates was estimated by the subcutaneous mouse assay. a positive linear relationship was found between the mean volumes of subcutaneous abscesses caused by the parasites in mice and severity of cervical epithelial abnormalities observed in the patients from whom these strains had been isolated. this relationship implies that virulence of the human urogenital trichomonad, as measured by the mouse assay, may be related to some factors associated with dysplas ... | 1984 | 6377149 |
| selective acquisition of plasma proteins by trichomonas vaginalis and human lipoproteins as a growth requirement for this species. | trichomonas vaginalis avidly bound numerous host macromolecules which were not removed by repeated washing in phosphate buffered saline. the use of radioiodinated cohn plasma fractions in binding studies allowed the identification of plasminogen, fibrinogen, immunoglobulin g, lipoproteins a and b, transferrin, alpha 1-antitrypsin, and albumin on intact organisms. the binding of immunoglobulin g, albumin, transferrin, and lipoproteins to intact, motile trichomonads was further demonstrated using ... | 1984 | 6379453 |
| prostatitis syndromes: pathophysiology, differential diagnosis, and treatment. | prostatitis syndromes are best understood in terms of the anatomy and physiology of the genitourinary tract. infections of the prostate may occur despite numerous host defenses of the male lower urogenital tract. histologic criteria for prostatitis correlate imperfectly with clinical and microbiologic findings. it is critical to distinguish patients with lower-urinary-tract complaints associated with bacteriuria from the larger number of patients without bacteriuria. careful lower-urinary-tract ... | 1984 | 6379919 |
| trichomonas vaginalis, tritrichomonas foetus, and trichomitus batrachorum: comparative proteolytic activity. | at least four proteolytic activities were detected in the lysates of each of trichomonas vaginalis, tritrichomonas foetus, and trichomitus batrachorum. these were hpaase, a dithiothreitol-dependent activity on hide powder azure; azcase, a dithiothreitol-dependent activity on azocasein; and two distinct activities towards peptide nitroanilide derivatives--one was optimally active at ph 7 and stimulated by dithiothreitol; the other had no dithiothreitol requirement and was highly active at ph 5. h ... | 1984 | 6389167 |
| [gardnerella vaginalis infection--another sexually transmitted disease]. | the gardnerella vaginalis infection of the urogenital tract, an std, is of clinical importance in females and of epidemiological importance in males. females suffer from vulvovaginitis amine colpitis, with a bad-smelling grey vaginal discharge with a ph of 5.0-5.5, which contains "clue cells". the urethra of males is often asymptomatically infected. the identification of g. vaginalis is time-consuming and requires a lot of material. isolation and identification of g. vaginalis can not yet be mad ... | 1984 | 6389437 |
| risk factors for prematurity and premature rupture of membranes: a prospective study of the vaginal flora in pregnancy. | prematurity remains a major cause of perinatal mortality in the united states. some research has indicated that infectious agents play a role in either initiating preterm labor, causing premature rupture of the membranes, or preventing tocolysis. this study attempted to determine if the presence of various vaginal pathogens in early pregnancy was associated with the subsequent development of premature rupture of membranes or preterm labor. we found that among 233 evaluable patients those with tr ... | 1984 | 6391179 |
| [value of indirect immunofluorescence and passive hemagglutination reactions in the detection of urogenital trichomoniasis]. | the indirect fluorescent antibody (ifat) and indirect hemagglutination tests (iha) were performed in 375 patients attending the venereal disease clinic (chu of rouen). in addition, wet mount, acridine orange stain and culture were used to detect trichomonas vaginalis in genital discharge. significant levels of antitrichomonas antibodies were present in sera, in 44 per cent of women with vaginal discharge and 23 p. cent of men with urethritis or prostatitis, whereas no evidence of trichomonal inf ... | 1984 | 6391297 |
| specific and common antigens of trichomonas vaginalis detected by monoclonal antibodies. | monoclonal antibodies to trichomonas vaginalis were prepared by immunizing mice with a cloned isolate of t. vaginalis. eight antibodies reacted with the same four isolates or strains but did not react with the other t. vaginalis strains or isolates tested. all eight antibodies reacted uniformly with both the body and flagella of t. vaginalis in the immunofluorescence assay but were unreactive by immunoblotting. the antigen(s) recognized by these antibodies was determined to be present on the sur ... | 1984 | 6360900 |
| prostatitis and epididymitis. | ascending spread of urethral pathogens may be the mechanisms of infection of the prostate and epididymis. sexually transmitted organisms cause most epididymitis in young men. although evidence is mounting to suggest that sexually transmitted organisms may cause prostatitis, data are insufficient at this time to base a therapeutic approach on this concept. the authors present approaches to the management of these two disorders. | 1984 | 6369708 |
| [studies on the animal model of trichomonas vaginalis]. | 1984 | 6335065 | |
| [usefulness of staining specimens with acridine orange in the diagnosis of trichomonas vaginitis]. | 1984 | 6335800 | |
| [antitrichomonal properties of an antiseptic drug cidizol-kb]. | 1984 | 6335801 | |
| new evidence elucidating the mechanism of action of gynatren/solcotrichovac. | 1984 | 6336149 | |
| the destructive effect of solcotrichovac-induced serum antibodies on trichomonas vaginalis; an electron microscopic investigation. | 1984 | 6336150 | |
| inhibition of growth of giardia lamblia by difluoromethylornithine, a specific inhibitor of polyamine biosynthesis. | difluoromethylornithine (dfmo) is a specific and irreversible inhibitor of ornithine decarboxylase, an enzyme which catalyzes the first step in the biosynthetic pathway of the polyamines. we tested the effect of dfmo on the growth of giardia lamblia, entamoeba histolytica, and trichomonas vaginalis. growth of g. lamblia was inhibited by dfmo at concentrations of greater than or equal to 1.25 mm. culture doubling time increased with increasing dfmo concentration. growth inhibition was reversed if ... | 1984 | 6330350 |
| susceptibility of trichomonas vaginalis to metronidazole. | 1984 | 6332727 | |
| [study of antibody responses in rabbits immunized with trichomonas vaginalis using serological reactions]. | 1984 | 6333267 | |
| pyrimidine metabolism in trichomonas vaginalis. | pyrimidine metabolism in trichomonas vaginalis was investigated using washed cell suspensions of the organism with radiolabelled pyrimidine ring precursors and preformed pyrimidines. the precursors [14c]orotate, [14c]bicarbonate and [14c]aspartate were not incorporated into the pyrimidine bases of trichomonal nucleic acids, indicating that the protozoan is unable to synthesise the pyrimidine ring and is dependent on the salvage of exogenous pyrimidines. [3h]uracil, [3h]uridine, [3h]cytidine, deo ... | 1984 | 6333357 |
| trichomonas vaginalis is dependent on uptake and degradation of human low density lipoproteins. | human plasma low density lipoprotein uptake by the urogenital pathogen, trichomonas vaginalis, was examined. rapid binding and internalization of 125i-labeled low density lipoproteins by live t. vaginalis was observed at 37 degrees c. data showing parasite degradation of the internalized apoproteins and lipid accumulation following low density lipoprotein uptake was obtained. acquisition of low density lipoproteins was by a trichomonad surface protein that possessed a molecular weight of greater ... | 1984 | 6333482 |
| a metronidazole-resistant strain of trichomonas vaginalis and its sensitivity to go 10213. | in the present study the comparative in-vitro and in-vivo efficacy of go 10213 was compared with those of metronidazole, secnidazole, tinidazole, ornidazole and nimorazole against a metronidazole-resistant strain of t. vaginalis. go 10213 was found to be superior in activity. it appears more promising than the drugs mentioned above on the basis of the evidence presented. | 1984 | 6334072 |
| acridine orange staining in the identification of trichomonas vaginalis. | 1984 | 6334422 | |
| soluble trichomonas vaginalis antigens in cell-free culture supernatants. | trichomonad proteins present in cell-free supernatants from logarithmic phase cultures of a pathogenic strain of trichomonas vaginalis were detected with enzyme-linked immunosorbent assay employing antibody from mice and rabbit antisera. numerous immunogenic membrane proteins of t. vaginalis were identified by immunoblotting of culture filtrate with rabbit antisera. released membrane antigens ranging in molecular weight from 30 000 to 300 000 under reducing conditions were also detected in radio ... | 1984 | 6334804 |
| [trichomoniasis in pregnancy. cultural and colpocytologic research on 208 asymptomatic pregnant women]. | 1984 | 6334820 | |
| [role of chlamydia, mycoplasmataceae and trichomonas vaginalis in non-gonococcal urethritis in men]. | 1984 | 6334872 | |
| nitroimidazoles in the treatment of trichomoniasis, giardiasis, and amebiasis. | nitroimidazoles have been extensively evaluated in the treatment of trichomoniasis, giardiasis, liver and intestinal amebiasis. the most widely used are metronidazole, tinidazole, ornidazole, and secnidazole. tinidazole, ornidazole, and secnidazole have a much longer half-life than metronidazole, allowing single-dose or once daily administration. nitro-5-imidazoles remain extremely effective drugs for treating protozoans, trichomonas vaginalis, entamoeba histolytica, and giardia intestinalis. al ... | 1984 | 6698665 |
| trachomoniasis in imo state, nigeria: a first report. | the prevalence of trichomonas vaginalis infection in imo state of nigeria is reported and adds to the meagre knowledge on its distribution in the country. the study (august 1978-march 1981) is based on 794 high vaginal swabs (hvs), 178 male urethral swabs (mus) and 5883 male and female urine samples obtained from out-patients at the owerri general hospital as well as 447 hvs from adult out-patients from holy rosary hospital, emekuku. 10.2% of 1241 hvs, 3.4% of 178 mus and 1.3% of 5883 urine sa ... | 1984 | 12340185 |
| clinical and microbiological characterization of patients with nonspecific vaginosis associated with motile, curved anaerobic rods. | the vaginal secretions of 20 normal control subjects and 21 patients with motile, curved anaerobic rods were cultured for aerobic and anaerobic bacteria, chlamydia trachomatis, herpes simplex virus, and trichomonas vaginalis. extensive histories and physical examinations of the patients and microscopic appearance and gas-liquid chromatography patterns of vaginal secretions were compared between the two groups. the patients who had motile rods in their vaginal secretions more frequently presented ... | 1984 | 6144713 |
| prevalence of six sexually transmitted disease agents among pregnant inner-city adolescents and pregnancy outcome. | 115 pregnant girls aged 13-17 years were investigated during the third trimester for endocervical infection with six sexually transmissible microorganisms. specimens from 21 patients destroyed the tissue cell monolayers for propagation of chlamydia trachomatis, but 11 were no longer toxic when recultured after freezing or with additional antimicrobial agents; trichomonas vaginalis was present in 76% of the toxic specimens. c trachomatis was recovered from 37% of 105 specimens. t vaginalis was re ... | 1984 | 6146874 |
| salvage of pyrimidine nucleosides by trichomonas vaginalis. | trichomonas vaginalis is incapable of de novo pyrimidine biosynthesis because it cannot incorporate bicarbonate, aspartate or orotate into its pyrimidine nucleotides or nucleic acids. the organism can salvage exogenous cytidine greater than uridine greater than uracil and thymidine, and incorporate them into the nucleotide pool. a portion of cytidine is converted to cmp, cdp and ctp by cytidine phosphotransferase and nucleotide kinases. some cytidine and most of uracil are, however, converted fi ... | 1984 | 6199666 |
| [unusual cytologic aspects of cervico-vaginal trichomoniasis. study of cervico-vaginal smears stained by the papanicolaou's method]. | trichomonas vaginalis has been recognized by cytologists in papanicolaou-stained smears of cervical and vaginal secretions for some years. the highest percentage of positive trichomonas vaginalis detection was obtained with this technique. classical cytologic aspects of trichomonas vaginalis infection on papanicolaou-stained smears have been commonly reported: cytoplasmic alterations with amphophilia, eosinophilia, perinuclear halo, vacuolisation; nuclear abnormalities with pycnosis, dysplasia-l ... | 1984 | 6203958 |
| iron uptake and increased intracellular enzyme activity follow host lactoferrin binding by trichomonas vaginalis receptors. | lactoferrin acquisition and iron uptake by pathogenic trichomonas vaginalis was examined. saturation binding kinetics were obtained for trichomonads using increasing amounts of radioiodinated lactoferrin, while no significant binding by transferrin under similar conditions was achieved. only unlabeled lactoferrin successfully and stoichiometrically competed with 125i-labeled lactoferrin binding. time course studies showed maximal lactoferrin binding by 30 min at 37 degrees c. data suggest no int ... | 1984 | 6088662 |
| the deoxyribonucleoside phosphotransferase of trichomonas vaginalis. a potential target for anti-trichomonial chemotherapy. | trichomonas vaginalis, a human protozoan parasite known to lack the capability of synthesizing purine and pyrimidine nucleotides de novo, was found also incapable of converting its ribonucleotides to deoxyribonucleotides. the only apparent means of providing deoxyribonucleotides for dna synthesis relies on salvaging exogenous deoxyribonucleosides by a deoxyribonucleoside phosphotransferase activity in the t. vaginalis 10(5) g pelletable fraction. the activity, constituted by at least two isozyme ... | 1984 | 6090576 |
| sexually transmitted diseases among randomly selected attenders at an antenatal clinic in the gambia. | one hundred randomly selected women attending a free government antenatal clinic in the town of bakau, the gambia, were examined. vaginal swabs were taken for microscopical examination for trichomonas vaginalis and for culture on sabouraud's medium. cervical swabs were taken for culture of neisseria gonorrhoeae and chlamydia trachomatis and, in 50 cases, herpesvirus hominis; in addition, urethral swabs were taken for culture of n gonorrhoeae. serum samples were tested for antibodies to treponema ... | 1984 | 6091843 |
| thiol groups on the surface of anaerobic parasitic protozoa. | evidence is presented that giardia lamblia and entamoeba histolytica, phylogenetically unrelated aerotolerant anaerobes, have crucial thiol groups on or easily accessible to their external surface. both parasites were killed by three structurally unrelated thiol-blocking reagents which penetrate intact cells poorly or not at all. the parasites were protected from p-chloromercuribenzenesulfonic acid (10-100 microm) by cysteine or by reduced glutathione. killing was arrested with identical kinetic ... | 1984 | 6096710 |
| non-gonococcal urethritis in men & its response to therapy. | 1984 | 6097537 | |
| [microbiologic findings in vaginal discharges]. | microbiological examinations were performed in 247 women complaining of vaginal discharge. an average of 3.9 different organisms was isolated from each patient. gardnerella vaginalis was found in 62.8% of all women. candida spp. were seen in 22.7%. trichomonas vaginalis occurred in 6.5%, neisseria gonorrhoeae in 1.2%, chlamydia trachomatis in 10.1%, mycoplasmata in 13.8%, cytomegalovirus in 2.8%, and herpes simplex type 2-virus in 1.1%. none of the above was found in 17.4% of the patients. stati ... | 1984 | 6098512 |
| infection with chlamydia trachomatis in female college students. | chlamydia trachomatis was isolated from genital specimens from 21 (4.9%) of 431 female college students. antibody to c. trachomatis was found in the genital secretions of 52 (11.9%) of 437 women. multiple logistic regression analysis showed race, number of sexual partners, and use of barrier methods of contraception to be predictive of infection with c. trachomatis. logistic regression analysis found race, number of sexual partners, use of barrier methods of contraception, and presence of cervic ... | 1985 | 3964985 |
| cytologic manifestations of cervical and vaginal infections. i. epithelial and inflammatory cellular changes. | we used multiple logistic regression to analyze microbiological and clinical correlates of inflammatory and epithelial cell changes on papanicolaou-stained cervical smears in patients from a sexually transmitted disease clinic. among randomly selected patients, increased numbers of histiocytes and polymorphonuclear leukocytes and the presence of transformed lymphocytes were associated with chlamydia trachomatis infection, while increased lymphocytes were associated with trichomonas vaginalis inf ... | 1985 | 3968836 |
| urogenital involvements and rheumatic disorders in females. an interview study. | to study dependence between urogenital involvements and musculoskeletal complaints in females, 311 randomly selected women aged 15 to 54 were interviewed. in the analysis of these dependences musculoskeletal complaints were considered as a whole per person. a history of salpingitis, gonorrhoea, urinary tract infection (uti) and trichomonas vaginalis was revealed as constituting a relative risk factor of 4.4, 3.9, 3.1 and 4.5 respectively in connection with inflammatory rheumatic disease or suspi ... | 1985 | 4006385 |
| electrophoretic analysis of soluble proteins and esterase, superoxide dismutase and acid phosphatase isoenzymes of members of the protozoan family trichomonadidae. | polyacrylamide gel electrophoresis was used to compare the proteins and isoenzymes of esterase, superoxide dismutase, and acid phosphatase in soluble, whole-cell extracts of four strains of trichomonas vaginalis, two strains of trichomonas gallinae, and one strain each of tritrichomonas foetus, tritrichomonas augusta, tetratrichomonas gallinarum, and pentatrichomonas hominis. intraspecific, interspecific, and intergeneric differences were found in protein and isoenzyme profiles. at least four to ... | 1985 | 4017542 |
| [simultaneous occurrence of trichomonas vaginalis and gonorrhea in women]. | 1985 | 4024310 | |
| clinical manifestations of female trichomoniasis and comparison of direct microscopy and culture media in its diagnosis. | a group of 125 women attending a gynecologic clinic was studied to assess the value of four culture media, wet smear and papanicolaou stained smears and also to re-evaluate the clinical picture in the diagnosis of trichomoniasis. there was no significant difference between the results of 4 different culture media but significant difference was obtained from fresh wet vaginal smears and culture media on the one hand and with papanicolaou stained smears on the other hand. during the survey, cultur ... | 1985 | 4028319 |
| epidemiologic and clinical factors of chlamydia trachomatis in black, hispanic and white female adolescents. | rates of genital infection with chlamydia trachomatis, neisseria gonorrhoeae and trichomonas vaginalis were determined prospectively in 396 sexually active female adolescents from three ethnically different urban teen clinics. the organisms were identified respectively in cultures of specimens from 21%, 7% and 6% of all adolescents; 28%, 16% and 20% of blacks; 23%, 4% and 2% of hispanics, and 14%, 2% and 1% of whites. c trachomatis was identified in specimens from 27% of pregnant adolescents and ... | 1985 | 4036112 |
| vaginal trichomoniasis at a sexually transmitted disease clinic at khartoum. | at a sexually transmitted disease clinic at khartoum 613 sudanese women presenting with vaginal discharge were investigated. specimens were examined by microscopy and culture. trichomonas vaginalis infestation was found in 123 patients (20.1%), predominantly in the age groups 16-19 years (27.1%) and 46-65 years (27%). frequency of trichomonal vaginitis was highest (35.9%) among divorced women. of the pregnant women investigated, 16.3% were found to harbour the parasite. there was no significant ... | 1985 | 4049503 |
| effects of trichomonas vaginalis on the ph and glycogen content of the vagina. | 1985 | 4054105 | |
| alterations of cervical cytology and steroid contraceptive use. | the alterations of cervical cytology in 3206 'users' of steroid contraceptives (sc) and 2394 'non-users' (controls) have been followed by means of five surveys for eight years. the alterations of cervical cytology have not differed significantly between the two groups seven years after the first examination, but have differed significantly between younger and older women in both groups. the incidence of progression to and regression from pap iii class cytology was more frequent than the prevalen ... | 1985 | 4055204 |
| the association of sexually transmitted diseases with cervical intraepithelial neoplasia: a case-control study. | thirty-three women with histologically confirmed cervical intraepithelial neoplasia (grades i to iii, with one case of microinvasive carcinoma) and 54 women without evidence of the disease were prospectively studied to determine the relationship of genital infection to cervical neoplasia. demographic and sexual data for patients and control subjects were collected, with standardized clinical and colposcopic evaluation by means of predefined diagnostic categories. cultures from the cervix were ex ... | 1985 | 2982264 |
| a linear double-stranded rna in trichomonas vaginalis. | a "double-stranded" rna was identified in the anaerobic, parasitic protozoan trichomonas vaginalis. electron microscopic evidence indicated linear double-stranded structure 1.5 micron in length, with no apparent hairpins or loops. boiling in 30% dimethyl sulfoxide denatured it into single strands of 1.5 micron and shorter fragments. it consists of 23.4% g, 23.4% c, 23.0% a, and 30.3% u and melts at a transition temperature of 81.7 degrees c in 75 mm nacl and 7.5 mm sodium citrate, ph 7.0, with 7 ... | 1985 | 2982874 |
| metronidazole radical anion generation in vivo in trichomonas vaginalis: oxygen quenching is enhanced in a drug-resistant strain. | the nitro radical-anion of metronidazole has been detected in vivo in the sexually transmitted human parasite, trichomonas vaginalis, under anaerobic conditions by electron spin resonance spectrometry. exposure of organisms to oxygen decreased the intensity of the radical signal in both metronidazole-sensitive atcc strain 30001 and in the metronidazole-resistant strain 85. the sensitive strain still gave radical signals at partial pressures of oxygen (greater than 6 kpa) sufficient to remove all ... | 1985 | 2985740 |
| isolation and differentiation of herpes simplex virus and trichomonas vaginalis in cell culture. | during the period january 1982 to january 1985, 2,234 specimens were cultured for isolation of herpes simplex virus (hsv). hsv was isolated from 23% of these, trichomonas vaginalis was isolated from 1.6%, and 75.3% were negative. in 0.2% of these, hsv and t. vaginalis were isolated from the same specimen. cytopathic effects produced by hsv were identified by their sensitivity to arabinosylthymine, whereas those produced by t. vaginalis were identified by their lack of sensitivity to arabinosylth ... | 1985 | 2993349 |
| epidemiology of cytomegaloviral infection in a heterogeneous population of pregnant women. | cervical cultures for cytomegalovirus (cmv) and samples of blood for antibody to cmv were obtained from 1,129 pregnant women: 57% of the women had antibody to cmv, and 14% of seropositive women shed virus. logistic regression analysis showed that seropositivity correlated with lower socioeconomic status, birth outside north america, multigravidity, older age, history of abnormal cervical cytology, infection with trichomonas vaginalis, a first pregnancy at less than or equal to 15 years of age, a ... | 1985 | 2993430 |
| monoclonal antibodies for the diagnosis of sexually transmitted diseases. | monoclonal antibodies are already being used for the diagnosis of human sexually transmitted diseases. these antibodies can be used to detect a wide range of microorganisms, including bacteria, parasites, and viruses. for both culture and direct tests, monoclonal antibodies showed patterns of specificity and reproducibility that exceeded those available with conventionally prepared antisera. the direct tests for these organisms required less than an hour to perform, representing a major advancem ... | 1985 | 2994946 |
| the generation of metronidazole radicals in hydrogenosomes isolated from trichomonas vaginalis. | the nitro radical-anion of the anti-trichomonal drug metronidazole has been detected by electron spin resonance spectrometry under anaerobic conditions in suspensions of intact hydrogenosomes isolated from the parasitic protozoon trichomonas vaginalis. metronidazole reduction was driven by pyruvate, but progressive damage to the radical generating system was observed. quenching of signals due to metronidazole radicals by chromium oxalate suggests that the radicals generated within the organelle ... | 1985 | 2999299 |
| [occurrence of trichomonas vaginalis infection in patients with neoplasms of the female genitalia]. | 1985 | 3834693 | |
| [a patient with urogenital trichomoniasis unsuccessfully treated due to resistance of the causative agent to nitroimidazole preparations]. | 1985 | 3871654 | |
| effect of culture medium iron content on the biochemical composition and metabolism of trichomonas vaginalis. | trichomonas vaginalis grown in iron-enriched medium contained increased concentrations of iron-sulfur proteins, including ferredoxin and pyruvate-ferredoxin oxidoreductase. the increases in hydrogenosomal constituents correlated with increased in vivo hydrogenosomal metabolism. | 1985 | 3871763 |
| "in vitro" effect of microtubule inhibitors on trichomonas vaginalis. | this paper describes the effects of some antimicrotubular drugs (mebendazole, flubendazole, thiabendazole, colchicine, griseofulvin, vinblastine and isopropyl-n-phenylcarbamate or ipc) on growth and viability of trichomonas vaginalis. among the inhibitors tested, mebendazole and flubendazole irreversibly inhibit protozoa growth at low concentration (greater than or equal to 1 microgram/ml), while colchicine and griseofulvin act at higher concentrations and thiabendazole and ipc are ineffective. ... | 1985 | 3871893 |
| sensitivity testing of trichomonas vaginalis using bromocresol purple indicator. | 1985 | 3872359 | |
| reduction of nitroimidazole derivatives by hydrogenosomal extracts of trichomonas vaginalis. | the reduction rate of nitroimidazole derivatives by pyruvate:ferredoxin oxidoreductase activity in ferredoxin depleted hydrogenosomal extracts of trichomonas vaginalis depended on the one-electron midpoint potential (e7(1)) of 15 compounds out of the 16 tested. the results showed a linear correlation with a positive slope between the logarithm of the rate and the e7(1) in the range from -564 to -260 mv. addition of t. vaginalis ferredoxin stimulated the reduction. the additional rate (stimulated ... | 1985 | 3872412 |
| in vitro inhibition of giardia lamblia and trichomonas vaginalis growth by bithionol, dichlorophene, and hexachlorophene. | bithionol, dichlorophene, and hexachlorophene, which are used in treating some helminthic infections, killed trophozoites of giardia lamblia and trichomonas vaginalis in modified bi-s-33 and asami media, respectively. virtually all g. lamblia and t. vaginalis cells were killed within 24 h with a 0.42 mm concentration of these compounds, except that 0.93 mm dichlorophene was required for sterilizing t. vaginalis in the same period. in modified bi-s-33 and asami media from which bovine and human s ... | 1985 | 3872626 |