Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| pentobarbital pharmacokinetics in the normal and in the hepatectomized rat. | the pharmacokinetics of pentobarbital, a barbiturate metabolized by the liver, was compared in normal and in hepatectomized rats. the blood concentration time curve following a single intravenous injection of pentobarbital was fitted to a two-compartment open model. both the volume of the central compartment and the elimination rate constant were significantly reduced in hepatectomized rats. it is concluded that the liver plays a role both in the metabolism and the distribution of pentobarbital. | 1975 | 1151743 |
| a study of absorption of compounds from the rat biliary tree by retrograde intrabiliary injection (rii). | absorption of compounds from the biliary tree of rats was studied by a retrograde intrabiliary injection (rii) technique. after rii of a number of compounds in volumes that exceeded the maximum distended capacity of the biliary tree, only that volume of rii solution which corresponded to biliary tree capacity remained therein. furthermore, this latter portion of rii solution was absorbed by a first-order process when the duration of bile duct cannula occlusion was extended. thus, the present stu ... | 1975 | 1151745 |
| effects of sodium acetylsalicylate on body temperature of monkeys under heat exposure. | exposure of taiwan monkeys to 38 degrees c ambient temperature caused: a) raised body temperature, b) restlessness and struggling, c) increased evaporative heat loss and d) increase in tail skin temperature. after the administration of sodium acetylsalicylate, 100 to 250 mg/kg intraperitoneally or 4 to 15 mg intracerebroventricularly (third ventricle) the same heat load caused: a) less increase in body temperature, b) no restlessness or struggling, c) an initially higher rate of evaporative heat ... | 1975 | 1151748 |
| proceedings: effects of histamine, 2-methylhistamine and 4-methylhistamine on blood pressure and vascular resistance in the cat. | 1975 | 1151865 | |
| dietary fats and properties of endoplasmic reticulum: i. dietary lipid induced changes in composition of microsomal membranes in liver and gastroduodenal mucosa of rat. | rats were fed for four weeks with different lipid diets to determine the effects on the endoplasmic reticulum membranes of the liver and on the postmitochondrial supernatant fraction of the gastroduodenal mucosa. the diets contained cholesterol, cacao butter, olive oil, and these in combination. the results showed that dietary lipids were able to modify the composition of the hepatic endoplasmic reticulum and, to a lesser extent, that of postmitochondrial fraction of gastroduodenal mucosa. cacao ... | 1975 | 1160521 |
| structural similarity of the membrane envelopes of rhizobial bacteroids and the host plasma membrane as revealed by freeze-fracturing. | the freeze-fracture technique was used to study the host plasma membrane and the membrane envelope of bacteroids in rhizobial root nodules of three host-rhizobium combinations. in all three combinations studied, the membrane envelopes of bacteroids are structurally similar to their host plasma membrane. however, the membrane appears to be reversed, because the number and arrangement of particles in the outer fractured face (face a, concave) and in the inner fractured face (face b, convex) of the ... | 1975 | 1168633 |
| transport and storage of serotonin by thrombin-treated platelets. | repeated thrombin treatment of washed platelets prepared from rabbits can decrease the serotonin content of the platelets by about 80%. when these platelets are deaggregated they reaccumulate serotonin but their storage capacity for serotonin is reduced by about 60%. if thrombin-pretreated platelets are allowed to equilibrate with a high concentration of serotonin (123 mu m), they release a smaller percentage of their total serotonin upon further thrombin treatment, in comparison with the percen ... | 1975 | 1168649 |
| [dynamics of cell divisions and involutions of immunocompetent cells of the axillary lymp nodes in conditioned and non-conditioned immunity in rats]. | 1975 | 1170630 | |
| differential potentiation by nystatin of the effect of antibiotics on yeast and mammalian cells. | the effect of the polyene antibiotic nystatin, used in combination with several other antibiotics, on the membranes of candida albicans sc#8169 (yeast) cells and of chinese hamster ovary and 3t3 (mammalian) cells was investigated. it was concluded from determinations of the viability of the yeast cells and from measurements of deoxyribonucleic acid synthesis by the mammalian cells that nystatin acts synergistically with several antibiotics on yeast cells, but not on cho and 3t3 cells. this selec ... | 1975 | 1171651 |
| time-dependent changes in commissural field potentials in the dentate gyrus following lesions of the entorhinal cortex in adult rats. | previous neuroanatomical work has shown that lesions of the entorhinal cortex in adult rats cause the commissural projections to spread from their normally restricted locus in the inner molecular layer approximately 40-50 mum into the outer molecular layer (that is, into the zone deafferented by the lesion). in the present study we measured the effects of the entorhinal lesion on the distribution of short-latency potentials elicited by commissural stimulation in the molecular layer. studies with ... | 1975 | 1175043 |
| endogenous prostaglandin release contributes directly to coronary artery tone. | an in vitro coronary artery preparation of beef heart was found to synthesize and release continuously large amounts of a prostaglandin of the e type. inhibition of prostaglandin synthesis with aspirin, indomethacin, or eicosa-5,8,11,14-tetraynoic acid induced a sustained contraction of the coronary artery, and pretreatment with indomethacin diminished markedly the output of prostaglandin into the bathing medium. it appears that prostaglandin e1, generated from within the vessel wall itself, may ... | 1975 | 1175084 |
| induction of aryl hydrocarbon hydroxylase in rat lung by marijuana smoke. | 1975 | 1179429 | |
| argemone mexicana poisoning in north india. | 1975 | 1184546 | |
| the histochemical activities of some oxidoreductases in the spinal ganglion of the embryonic and the adult rat. | 1975 | 1188273 | |
| the double domain structure of rhodanese. | 1975 | 1195402 | |
| pharmacological investigations on elaeocarpus ganitrus. | 1975 | 1197422 | |
| proceedings: anaesthetics in porphyria: intravenous induction agents. | 1975 | 1201181 | |
| some observations on the possible nutritional significance of vitamin b12-and folate-binding proteins in milk. absorption of [58co]cyanocobalamin by suckling piglets. | 1. a study was made of absorption of [58co]cyanocobalamin in suckling piglets. cyanocobalamin given at birth and at 7 d of age was efficiently absorbed from the intestine and retained within the body, mostly in the liver. a 10 mug test dose was absorbed no less efficiently than 2-5 mug, despite the virtual absence of intrinsic factor in the gut. in piglets given a 10 mug test dose at different ages between 2-5 and 56 d, there was a marked decrease in the efficiency of retention between about 7 a ... | 1975 | 1201270 |
| metabolic studies of [75se]selenocystine and [75se]selenomethionine in the rat. | 1. the long-term fate in rats of an oral dose of [75se]selenocystine was compared with that of an oral dose of [75se]selenomethionine. 2. urinary and faecal radioactivities were measured during the 1st week and whole-body radioactivity was determined for 10 weeks. rats were killed at weekly intervals for 4 weeks and at weeks 6 and 10 for analysis of tissue distribution of 75se. 3. intestinal absorption of [75se]selenocystine was 81% of the administered dose; that of [75se]selenomethionine was 86 ... | 1975 | 1201271 |
| [variety of effects of vitamins on yeast cells in aerobic conditions]. | the effect of thiamine and biotin on the processes of cell division, assimilation of glucose, and accumulation of the biomass and nitrogen in the cells was studied with the candida yeast. the action of the vitamins depended on the source of nitrogen. in some strains, asparagine can substitute for biotin. biotin has different effect on the production of gamma-aminobutyric acid in candida pulcherrima, c. guilliermondii. c. tropicalis k3-10. high concentrations of arginine were found in c. guillie ... | 1975 | 1214604 |
| [electron microscopic study of double infection induced by potato virus x and potato virus y in nicotiana glutinosa]. | 1975 | 1214639 | |
| [changes of the inner ear in experimental stapedectomy]. | 1975 | 1230953 | |
| [effusions in the dog. 1. clinico-diagnostic study with special reference to the cytology of the fluid]. | 1975 | 1231052 | |
| [effect of denervation of the nasal accessory sinuses on th morphology of mucous membrame (experimental study)]. | 1975 | 1231130 | |
| stimulation and inhibition of dna synthesis in rat thymocytes: action of concanavalin a and wheat germ agglutinin. | 1975 | 1234047 | |
| numerical analysis and computerized identification of the yeast genera candida and torulopsis. | numerical analysis of the published standard descriptions of 104 species of candida and 48 species of torulopsis suggested that the number of species should be reduced to 78 and 33 respectively. four examples are noted of closely matched species differing in ability to assimilate nitrate; these species may be combined as nitrate-variable species. although the ability to form pseudomycelium is the only important difference between the genera, only three examples were noted of candida and torulops ... | 1975 | 1236931 |
| [observations on the sensitivity to antibiotics of the shigella isolated from patients in 1966-1973]. | sensitivity to levomycetin, streptomycin, chlortetracycline, oxytetracycline, monomycin, neomycin and erythromycin of 3766 strains of shigella isolated from dysentery patients within 1966-1973 was determined with the method of standard discs. the strains proved to be resistant to tetracycline (94.3-99.4 per cent), streptomycin (85.1-94.9 per cent) and levomycetin (69-93.1 percent). by present the dysentery bacilli have preserved their sensitivity to monomycin (88.2 per cent) and neomycin (98.2 p ... | 1975 | 773290 |
| [the influence of several prophages on the genetic behavior of flexner dysentery bacteria]. | in conjugation experiments of escherichia coli k-12 hfr strains and converted clones of shigella flexneri var. y(-:3,4) that had acquired the capacity to synthesize type of antigens iv or v it is confirmed that the locus linked to lac-pro region in sh. flexneri chromosome called tp locus is a site of an attachment of prophages responsible for certain type specific antigens. lac+ hybrids of the clone converted by phage iv lost the type specific antigen iv with the frequency comparable with the lo ... | 1975 | 773758 |
| [bacteriological and epidemiological considerations on shigelloses in south vietnam (1969-1973)]. | during the period from 1969 to 1973, a rectal swabs from 13.943 diarrhea patients of all ages were examined by bacteriological surveys. from these specimens, 981 strains of shigella were isolated. the most commonly encounted were shigella flexneri 2. all of strains of shigella isolated were highly resistant to aureomycin, tetracyclin, terramycin, novobiocin and chloramphenicol. there has been an increase in the development of multiresistance of shigella. colimycin and streptomycin were the most ... | 1975 | 770024 |
| [characteristics of the salmonella and shigella strains isolated from diarrhea patients during antibiotic therapy]. | drug resistant strains of salmonella and shigella were isolated from diarrhoeic children during antibiotic treatment. two strains of sh. flexneri serotype 2a, resistant to sulfonamides, streptomycin,chloramphenicol, and tetracyclines, were able to transfer "en bloc" their resistances to e. coli k12. | 1975 | 776095 |
| studies on the survival of shigella flexneri in river and tap water. | 1975 | 776123 | |
| proceedings: on new biological responses of conventional adult mice administrated with bacterial endotoxin. | 1975 | 778449 | |
| [importation of shigelloses into the german democratic republic]. | 1975 | 779290 | |
| [an electron microscopic study of the interaction between shigellae and cell cultures. ii. structuro-functional response of the chief cytoplasmic organoids of infected cells]. | the initial mobilization of the protective power of amniotic cells under the influence of the intracellular parasite shigellae flexner was shown using qualitative and quantitative methods of electron microscopy. this mobilization is seen in the appearance and then concentration of membrane elements of the endoplasmic reticulum around the bacteria. the character of some degenerating changes confirms the opinion about the presence of an excreting endotoxin fraction in shigellae flexner. | 1975 | 781958 |
| the effect of leukocyte hydrolases on bacteria. iii. bacteriolysis induced by extracts of different leukocyte populations and the inhibition of lysis by macromolecular substances. | the lysis of 14c-labeled bacteria by hydrolases of human and rabbit leukocytes was studied in vitro. while staphylococcus albus, streptococcus faecalis, and streptococcus mutans were highly susceptible to lysis, staphylococcus auresus was intermediate in its susecptibility to lysis by the leukocyte enzymes. group a streptococcus, listeria monocytogenes, shigella flexneri, escherichia coli, and mycobacterium smegmatis were very resistant to degradation by these enzymes. the lytic activity of leuk ... | 1975 | 804017 |
| trimethoprim-sulfamethoxazole in the treatment of gastrointestinal infections, including enteric fever and typhoid carriers. | forty-three patients suffering from typhoid fever, 11 from paratyphoid fever, six from bacillary dysentery caused by shigella flexneri, and nine carriers of salmonella typhi or s. paratyphi b, have been treated with trimethoprim-sulfamethoxazole compound. fifty-one of the 54 patients who had typhoid fever or paratyphoid fever responded satisfactorily to treatment. two patients with typhoid fever failed to respond and one died. in the patients with bacillary dysentery acute symptoms subsided rapi ... | 1975 | 805647 |
| substituted 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones. | a series of 1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones has been prepared. a new synthesis of 4-alkyl-1-[(5-nitrofurfurylidene)amino]-4-imidazolin-2-ones involving the oxidative ring closure of 5-nitro-2-furaldehyde 2-(2-hydroxyethylalkyl)semicarbazones is described. the in vitro testing of the compounds against a variety of bacteria is reported. | 1975 | 807733 |
| divalent cation stimulation of the cell infectivity of shigella flexneri 2a. | 1975 | 807763 | |
| arylamidase activity of salmonella species. | arylamidase activity in cell extracts of sonically cell treated suspensions of 23 salmonella strains, including 12 strains of s. typhimurium, was investigated. all cultures hydrolyzed five of nine different neutral and basic substrates. activity against aspartyl-, cystyl- histidinyl-, and isoleucyl-beta-naphylamide was negligible. alanyl-beta-naphthylamide was the preferred substrate for the salmonella species; however, specific activities ranged widely. of several gram-negative organisms survey ... | 1975 | 808165 |
| transmissible drug resistance in shigella and salmonella isolated from pet monkeys and their owners. | during two dysentery outbreaks in primate pet owners, shigella and salmonella strains were isolated from the enteric flora. in both outbreaks the source of infection was traced to asymptomatic spider monkeys (ateles geoffroyi). the spider monkeys and their owners shed multiply drug-resistant shigella and salmonella serotypes. six of the nine bacterial strains isolated from the animals were multiply drug-resistant and capable of transferring antibiotic resistance patterns. | 1975 | 808621 |
| [antibacterial activity of a lysozyme-like enzyme from staphylococci]. | a lysozyme-like enzyme isolated from the culture broth of staph. aureus 712 presented in its native state a lipoproteid complex. the lytic and antibacterial spectrum of the enzyme was similar to that of the egg albumin enzyme. however, the lipoproteid complex was somewhat superior to the egg albumin complex in its activity against micrococcus lysodeikticus, a number of gramnegative bacteria and staphylococci. out of the organisms studied microccus lysodeikticus, sarcina and bac. subtilis proved ... | 1975 | 813563 |
| [the nature of nuclear enlargement in urethane and isoprotenol-stimulated salivary glands (author's transl)]. | 1975 | 1073694 | |
| [the acute vestibular paralysis (author's transl)]. | acute vestibular paralysis may not be considered as a nosologic entity but as a syndrome. symptomatology (vertigo, spontaneous and provoked vestibular nystagmus, absence of cochlear signs) shows an uniform picture. the results of the caloric test as well as the nystagmic responses induced by galvanic stimulation and the development of central vestibular compensation however indicate that the site of the lesion is not only confined to the labyrinth but may also occur at the level of the periphera ... | 1975 | 1081389 |
| drug evaluation of pyrantel pamoate against ancylostoma, toxocara, and toxascaris in eleven dogs. | eleven dogs dosed at approximately the recommended rate of 1.029 mg of pyrantel pamoate/kg of body weight were used. the efficacy against ancylostoma in the 11 dogs was 99% (av; min-max, 94-99%). in 4 dogs with both toxocara and ancylostoma, average efficacy against toxocara was 96%, and in 5 dogs with both toxoscaris and ancylostoma, efficacy against toxascaris was 93%. only 2 dogs of the 11 were infected with the 3 species; the average efficacy was 90%. there appeared to be no activity against ... | 1975 | 1057855 |
| multiple active forms of thrombin: binding to platelets and effects on platelet function. | the effect of various forms of thrombin on certain platelet functions has been investigated. partially purified bovine thrombin which is a mixture of multiple active forms of thrombin, was chromatographed to yield molecular species termed alpha-, beta-, and gamma-thrombin, each of which has varying degrees of fibrinogen clotting and esterase activities. a direct correlation was observed between the ability of the different forms of thrombin to clot fibrinogen and to influence platelet function. ... | 1976 | 1064039 |
| homologous inhibitors from potato tubers of serine endopeptidases and metallocarboxypeptidases. | a potent polypeptide inhibitor of chymotrypsin has been purified from russett burbank potatoes. the inhibitor has no effect on bovine carboxypeptidases a or b but exhibits homology with a carboxypeptidase inhibitor that is also present in potato tubers. the chymotrypsin inhibitor has a molecular weight of approximately 5400 as estimated by gel filtration, amino acid analysis, and titration with chymotrypsin. the polypeptide chain consists of 49 amino acid residues, of which six are half-cystine, ... | 1976 | 1064864 |
| treatment of spontaneous leukemia in akr mice with chemotherapy, immunotherapy, or interferon. | akr mice are genetically destined to develop gross (rna) virus-induced lymphatic leukemia. leukemic akr mice treated with combination vincristine, cyclophosphamide (cytoxan), and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea sustained a 180% increase of life-span. combination chemotherapy plus immunization with neuraminidase-treated allogeneic (gross virus-induced) g2g leukemic cells intradermally resulted in 35% of animals surviving beyond 150 days without evidence of the disease ... | 1976 | 1082796 |
| lysozyme synthesis by established human and murine histiocytic lymphoma cell lines. | a human cell line established in culture from a histiocytic lymphoma patient synthesizes and secretes the monocyte-granulocyte specific enzyme lysozyme. 18 other human cell lines with characteristics of t-lymphocyte, b-lymphocyte, burkitt's lymphoma, non-burkitt's lymphoma, myeloma, and bone marrow epithelial cells were not associated with lysozyme. among murine cell lines, lysozyme was produced by (a) three histiocytic lymphoma or macrophage lines, which mediate antibody-dependent phagocytosis ... | 1976 | 1083890 |
| t-dependence of human b lymphocyte proliferative response to mitogens. | human peripheral blood and tonsil lymphocytes were fractionated on anti-ig-coated sephadex columns or by centrifugation after rosetting with native sheep erythrocytes. both methods allowed the recovery of b and t-enriched populations the purity of which was checked by fluorescein-labelled anti-ig serum, e and eac rosette formation, and heterologous antisera specific for b or t lymphocytes. the proliferative response of t cells to pha, con a, pwm, and als was not found different from that of unfr ... | 1976 | 1084330 |
| multiple h-2 linked immune response gene control of h-2 d-associated t-cell-mediated lympholysis to trinitrophenyl-modified autologous cells: ir-like genes mapping to the left of i-a and within the i region. | one of the more recent associations of the murine h-2 major histocompatibility complex (mhc) with immune function has been the finding that cytotoxic t-effector cells generated by sensitization with viral-infected (1-6), chemically modified (7-9), or weak transplantation antigen-associated (10,11) syngeneic cells can efficiently lyse target cells which express the same viral, chemical, or weak antigenic agent, and which share the h-2k and/or h-2d regions of the mhc with the responding and/or sti ... | 1976 | 1087329 |
| effects of thymectomy and antithymocyte serum on spontaneous regression of friend virus-induced erythroleukemia. | to evaluate the role of immune response in regression of leukemia, we studied the effect of immunosuppression on the spontaneous regression of a leukemia induced by a specific strain of friend murine leukemia virus complex (rfv). thymectomy of newborn but not adult outbred swiss mice markedly inhibited regression. the effect of antithymocyte serum (ats) on regression depended on the timing of ats treatment. regression was markedly inhibited in leukemic mice given ats just before the start of reg ... | 1976 | 1087346 |
| ampicillin-resistant strains of haemophilus influenzae type b in north carolina. | 1976 | 1087376 | |
| fluid and electrolyte transport in rhesus monkeys challenged intracecally with shigella flexneri 2a. | shigella flexneri 2a is an invasive enteric pathogen that may produce diarrhea when ingested by human beings and subhuman primates. we have previously shown that shigella diarrhea correlates with water and electrolyte transport abnormalities in the jejunum and colon. dysentery alone is associated only with colonic transport abnormalities. to define the relationship between invasion and inflammation of the colon and the occurrence of jejunal transport abnormalities, we studied water and electroly ... | 1976 | 823110 |
| glycerol dissimilation and its regulation in bacteria. | 1976 | 825019 | |
| irradiation of cells by single and double pulses of high intensity radiation: oxygen sensitization and diffusion kinetics. | the biological effects of ionizing radiation in living cells are the ultimate result of a long chain of events with the initial step being the local absorption of radiation. whereas such physical abosrption is probably over within 10(-16) s after dose delivery, the biological consequences of radiation do not manifest themselves until very much later times. between these two extremes of time, events occur relatively early at the molecular level which are undoubtedly critically related to the stil ... | 1976 | 826371 |
| recurrent urinary tract infection due to shigella flexneri--case report. | a case of urinary tract infection due to shigella flexneri is reported. the case presented suggests that in persistent and recurrent urinary tract infection in topical countries, investigations for organisms such as shigella flexneri should be considered. urinary tract infection due to shigella flexneri is unknown and as far as we known has not been reported in the literature. a case report is presented in whom recurrent urinary tract infection was due to shigella flexneri and was treated effect ... | 1976 | 826670 |
| [use of the neutralization test for mass population studies]. | the authors applied the antibody neutralization test (ant) for detection of causative agent of intestinal infections in feces of healthy population in turkmenia. some part of the material was studied in parallel with the aid of the ant and by the bacteriological method. as a result of comparison it appeared that in using the ant causative agents of intestinal infections were revealed much more frequently than by the bacteriological method; in this connection this serological method can be recomm ... | 1976 | 828825 |
| [the role of the water factor in the spread of dysentery on river vessels]. | results of epidemiological and statistical analysis of the indices of dysentery morbidity and bacteriological examination of drinking water pointed to the significant role of the water factor in the spread of dysentery on the river vessels. | 1976 | 782097 |
| [increasing the frequency of the transmission of antibiotic resistance in bacteria through their centrifugal sedimentation]. | 1976 | 782110 | |
| [use of the vshs elective-differential medium in the diagnosis of dysentery and other acute intestinal infections]. | results of trial of the vshs medium under conditions of direct seeding feces of patients suffering from dysentery and other acute intestinal disturbances demonstrated that by the efficacy of sh. sonnei isolation it failed to differ from ploskirev's bactoagar, was less effective in comparison with levin's medium with levomycetin (the incidence of shigella isolation was 49.7, 52.6 and 60.3%, respectively) and was the most effective in sh. newcastle isolation. in seeding feces after their enrichmen ... | 1976 | 782114 |
| antigenicity testing of inactivated oral enteric bacterial vaccines for human use. | this study deals with the laboratory testing of the antigenicity of inactivated oral enteric bacterial vaccines for human use, viz. typhoid, dysentery, escherichia coli and cholera vaccines. for the assays the following methods are applied : 1) various types of active mouse protection tests 2) serum and coproantibody determinations in immunized persons and experimental animals, 3) protective ability of the immune sera in mice and embryonated eggs, 4) hemolytic and bacteriolytic plaque assays. it ... | 1976 | 782974 |
| [epidemiology of bacterial dysentery in the usa]. | 1976 | 785885 | |
| [antibody-containing cells in the mucosa of the large intestine of patients with acute bacterial dysentery]. | the authors traced the dynamics of appearance, increase and disappearance of o-antibody-containing cells in the mucosa of the distal portion of the large intestine in patients suffering from acute sonne and flexner dysentery (aspiration biopsy of the mucosa). the antibodies were revealed by the indirect coons method. the total number of cells per 1 mm2 of 4 mum of the mucosal section the number of lymphoid cells and the content of the antibody-containing cells in % per total cell count of the ly ... | 1976 | 785886 |
| fecal steroids in diarrhea. i. acute shigellosis. | fecal bile acid and neutral sterol patterns of five healthy adult male volunteers, who were challenged by a virulent shigella flexneri 2a (m42-43) strain and developed dysentery were studied. it was observed that cholic acid was increased from 1.9 +/- 0.4% of total bile acid in the feces before infection to 14.5 +/- 2.1% during diarrhea (p less than 0.001). chenodeoxycholic acid also was increased from 3.2 +/- 0.7 to 8.7 +/- 3.2% in diarrhea but the difference was not significant statistically. ... | 1976 | 786002 |
| [ 771 shigella strains isolated in a 15-year period from americans living in ankara. comparisons with shigella strains isolated from turkish natives]. | the author had worked as a bacteriologist in ankara american air force hospital from 1958 to 1972. during this period of time he was able to isolate 771 shigella strains from the american patients of the hospital. the amounts and the percentages of the subgroups are listed below together with the two other ankara city pediatric hospital results (see article). american community lived in ankara for 15 years and shared many aspects which were important in shigella epidemiology like using city's ta ... | 1976 | 790107 |
| shigellosis in custodial institutions. v. effect of intervention with streptomycin-dependent shigella sonnei vaccine in an institution with endemic disease. | a double-blind controlled field trial of live, oral, streptomycin-dependent shigella sonnei vaccine was begun in an institution with endemic s. sonnei disease. considerable unexpected child-to-child transmission of the vaccine strains inadvertantly caused the field trial to resemble a mass vaccination campaign. although s. sonnei accounted for 90% of shigella infections from 1968 to 1971 and three-fourths of the cases occurred in the seven study cottages, s. sonnei disease disappeared following ... | 1976 | 779465 |
| proceedings: inactivation and mutation of cultured mammalian cells by radiations of different let. | 1976 | 779917 | |
| serum amylase in rats following the administration of endotoxin. | 1976 | 781914 | |
| shigella flexneri 6 biotypes: a review. | except in gas production, s. flexneri 6 is generally similar to other s. flexneri. s. flexneri 6 contains both aerogenic and anaerogenic strains which are identical serologically. it is not surprising that s. flexneri 6 is not separable from other s. flexneri types on the basis of dna relatedness (overall genetic makeup) (4). the manchester biotype is seen in the united states, and is easily separable from other enterobacteriaceae by biochemical tests. one can no longer assume à priori that any ... | 1976 | 776900 |
| isolation and analysis of the lipid a backbone. lipid a structure of lipopolysaccharides from various bacterial groups. | a degradation procedure of lipopolysaccharides was worked out which allows the isolation of the reduced backbone of lipid a in a total yield of between 20 and 30%. this procedure was applied to lipopolysaccharides of s forms (salmonella minnesota, shigella flexneri 5b, escherichia coli 086, e. coli 0111, xanthomonas sinensis, rhodopseudomonas gelatinosa) and r mutants (salmonella minnesota, shigella flexneri, 5b, e. coli bb9 and e. coli eh 100). chemical analysis, reaction with beta-n-acetyl-glu ... | 1976 | 770165 |
| shigella hepatitis. | 1976 | 775138 | |
| [correlation between biochemical features and pathogenicity of shigella. iv. threonine deaminase of shigella strains producing and not producing keratoconjunctivitis in guinea pigs]. | 1976 | 775224 | |
| trimethoprim-sulfamethoxazole therapy for shigellosis. | twenty-eight infants and children hospitalized for severe shigellosis were treated orally either with ampicillin trihydrate (100 mg/kg/day administered in divided doses every six hours) or with trimethoprim-sulfamethoxazole (trimethoprim, 10 mg; sulfamethoxazole, 50 mg/kg/day in divided doses every 12 hours) for five days. four patients with ampicillin-resistant shigellae continued to have diarrhea and positive stool cultures during therapy. patients with susceptible shigellae treated with ampic ... | 1976 | 765518 |
| chemical modification as a probe of the topography and reactivity of horse-spleen apoferritin. | in apoferritin, but not in ferritin, 1.0 +/- 0.1 cysteine residue per subunit can be modified. in ferritin 3.3 +/- 0.3 lysine residues and 7.1 +/- 0.7 carboxyl groups per subunit can be modified, whilst the corresponding values for apoferritin are 4.4 +/- 0.4 lysine residues and 11.0 +/- 0.4 carboxyl groups per subunit. modification of lysine residues which maleic anhydride and carboxyl groups with glycineamide in apoferritin which has been dissociated and denatured in guanidine hydrochloride le ... | 1976 | 1248472 |
| familial clustering of selective iga deficiency. | serum iga levels of 35 healthy iga-deficient index cases, of their 180 first-degree relatives, and of 31 other family members were studied. iga deficiency was detected in 7.2% of the first-degree relatives, which is significantly more than the 0.25% frequency of iga deficiency in healthy finnish blood donors. subnormal serum iga levels were found in additional 13 (7.2%) first-degree relatives. the familial clustering of iga deficiency seemed to be controlled by multigenic factors. iga-deficient ... | 1976 | 1251582 |
| [diagnostic problems in gout in a 44-year-old man]. | 1976 | 1251615 | |
| the detection of antibodies in human and animal filariases by counterimmunoelectrophoresis with dirofilaria immitis antigens. | counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. antigens used in the test were prepared from microfilariae and adult male d. immitis. some humans and animals had antibodies to both antigens while others had antibodies against microfilariae or adult worms only. the presence of soluble circulating ... | 1976 | 1262695 |
| attenuated, streptomycin-dependent salmonella typhi oral vaccine: potential deleterious effects of lyophilization. | four studies were done with streptomycin-dependent salmonella typhi as an oral, attenuated vaccine. studies 1 and 3 employed freshly harvested vaccine, whereas studies 2 and 4 involved lyophilized vaccine. five to eight doses (3 x 10(10)-10(11) organisms/dose) were given; oral streptomycin (1.0 g) was administered concomitantly in studies 2 and 3, with only two of the doses of vaccine in study 1, and was not given in study 4. no adverse reactions were encountered in 179 vaccinated men, and 94% o ... | 1976 | 1262709 |
| measurement and alteration of the capacity of the distended biliary tree in the rat. | 1976 | 1273853 | |
| [changes in the activity of succinate dehydrogenase in the cells of different brain structures under the effect of uhf field of low intensity]. | 1976 | 1274298 | |
| glial cells and extracellular potassium: their relationship in mammalian cortex. | simultaneous recordings were made of glial cell potentials and the extracellular potassium concentration ([k+]o) in cat cortex in an attempt to provide more quantitative information about the sensitivity of mammalian neuroglia to changes in [k+]o. a penicillin epileptogenic focus served to generate both transient and sustained elevations in [k+]o, thus allowing measurement of glial membrane potential (vm) at both resting and increased [k+]o levels many times during the same experiment. resting v ... | 1976 | 1276917 |
| absolute configuration of 3-hydroxy fatty acids present in lipopolysaccharides from various bacterial groups. | the absolute configuration of 3-hydroxy fatty acids has been studied, which are present in the lipopolysaccharides of the following bacteria: phodopseudomonas gelatinosa, rh. viridis, rhodospirillum tenue, chromobacterium violaceum, pseudomonas aeruginosa, bordetella pertussis, vibrio metchnikovii, vibrio cholerae, salmonella spp., escherichia coli, shigella flexneri, proteus mirabilis, yersinia enterocolitica and fusobacterium nucleatum. the 3-hydroxy acids were liberated by strong alkaline hyd ... | 1976 | 1278168 |
| shigellosis transmitted by nurses. | twelve cases of shigella sonnei infection, with two deaths, occurred at a custodial institution in donelson, tennessee, in april and may 1973. nine of the cases and both deaths were in patients hospitalized at the institution's infirmary. the patients with nosocomial shigellosis were significantly younger and had been hospitalized significantly longer than controls. epidemiologic investigation implicated staff members in the transmission of illness from one patient to another and identified the ... | 1976 | 790590 |
| [cytotoxic factor of flexner shigella, its biologic function and genetic control]. | 1976 | 790817 | |
| [role of the cytotoxicity of shigellae in the infectious process]. | 1976 | 790818 | |
| [realization of the cytotoxic properties of flexner shigellae in a macrophage culture at the cellular and subcellular level]. | 1976 | 790819 | |
| [change in the virulence of flexner shigellae following transmission of several parts of chromosomes related to the synthesis of o-antigen lipopolysaccharide from e coli k-12 and r-mutants of shigellae]. | 1976 | 790821 | |
| [comparative study of the virulence of an antibiotic-sensitive strain of flexner dysentery and its exconjugants with different r-factors acquired in the experiment]. | 1976 | 790825 | |
| [transmissive plasmid determining hemolysin production and synthesis of thermolabile k-antigen]. | 1976 | 790826 | |
| on the metabolic characteristic of hybrids shigella flexneri x escherichia coli devoid of their ability for intracellular multiplication in the epithelial cells. i. glycolysis. | the glycolysis (aerobic and in the presence of kcn) of avirulent xyl+ and xyl-str hybrids sh. flexneri x e. coli, devoid of their ability to multiply intracellularly in the epithelial cells, is studied. it is established that their glycolytic activity is considerably higher than the activity of the donor strain e. coli, and deviate significantly compared with shown activity of the virulent recipient strains sh. flexneri. xyl-str hybrids are showing high values of glycolysis in aerobic conditions ... | 1976 | 790853 |
| on the metabolic characteristic of hybrids shigella flexneri x escherichia coli devoid of their ability for intracellular multiplication in the epithelial cells. ii. catalase and phosphatase activity. | the catalase and phosphatase activity of avirulent by keratoconjunctival test of guinea pigs xyl+ and xyl-str (kcp-) hybrids that have lost their ability for intracellular multiplication, received from virulent strains. sh. flexneri (sh. flexneri 222 5 a and sh. flexneri m42-43) and donor strain e. coli ab 313 was investigated. it is established that there is a definite dependence between the changes in the catalase and the phosphatase activities of the hybrid strains and the newly received by t ... | 1976 | 790854 |
| shigellosis in the united states: ten-year review of nationwide surveillance, 1964-1973. | in the 10 years 1964-1973, 105,832 isolations of shigellae were reported to the center for disease control through a nationwide surveillance system. the number reported increased by approximately 13% annually, from 5852 in 1964, when only 17 centers reported all 4 quarters; to 16,797 in 1973, when 52 centers reported each quarter. the rate of reported isolations varied from 4.6 per 100,000 persons in 1965 to 9.1 per 100,000 in 1973. shigella sonnei accounted for 64% of all these isolates and for ... | 1976 | 790947 |
| [effect of specific sensitization of the body on the clinical symptoms of dysentery]. | 1976 | 793040 | |
| studies on the energetic metabolism of shigella flexneri x escherichia coli hybrids devoid of penetration ability. iv. growth characteristics in the presence of some tricarboxylic acid cycle intermediates. | the dynamics of avirulant lac+kcp- hybrids sh. flexneri multiplication was investigated in minimal medium in the presence of some tricarboxylic acid cycle intermediates (fumarate, succinate, malate) and pyruvate. it was established that in spite of the loss of virulence in the rate of the multiplication of the hybrid strains, in comparison with that of the virulent recipient strains of sh. flexneri, considerable differences were not observed. | 1976 | 793258 |
| [free amino acid content in the blood and urine from the use of monomycin on children with dysentery]. | the progress of acute dysentery in 73 children at the age of 1 to 14 years treated with monomycin and the levels of free amino acids in the blood and urine in dynamics were studied. it was found that the blood levels of 6 amino acids in the children treated with the antibiotics significantly decreased, while those of 3 amino acids increased as compared to the levels of the same amino acids in the children treated without the antibiotics. it was concluded that the diet of dysentery children treat ... | 1976 | 793513 |
| [change in the sensitivity of dysentery bacteria to certain antibiotics, furazolidone and antifungal preparations when cultured together with candida albicans]. | the effect of candida albicans (2 collection cultures and 1 freshly isolated culture) on sensitivity of dysentery bacteria (5 zonne strains, 4 flexner strains and 2 newcastle strains) to antibiotics, furazolidone and their combinations with nystatin or decamine was studied by the method of serial dilutions. a total of 937 tests were performed with the use of 10 concentrations in each test. it was found that sensitivity of the shigella to levomycetin succinate, monomycin and furazolidone decrease ... | 1976 | 793515 |
| studies on the relationships between the immunogenicity and catabolism of antigens and their binding to the surface of macrophages. | the relationship between immunogenicity of shigella paradysenteriae, the branched synthetic polypeptide poly-l (tyr, glu)-polylpro-polyllys [(t, g)-pro--l] and human albumin (hsa) interacting with macrophages and kinetics of antigen degradation and degree of binding to the cell surface was studied. following thioglycollate inoculation into c57bl/6 mice, the peritoneal-stimllated macrophages had higher levels of hydrolases as compared to unstimulated cells. the lysates of the stimulated macrophag ... | 1976 | 793850 |
| [formation of f'-episomes in flexner shigellae]. | genetic characteristics of shigella flexneri virulent donor strain 3s, isolated in the laboratory, are studied. the data obtained showed that sh. flexneri 3s 6832 is of f'protype it did not transmit even closely located chromosome markers, except pro+. the transition of pro+ marker was reproduced in reca- strain. f'pro plasmid was eliminated with a frequency similar to that of f'lac factor in the control strain of escherichia coli. the study of virulence by means of keratoconjunktival test revea ... | 1976 | 793929 |
| phage-dependent changes in shigella flexneri type antigen synthesis. | lysogenic conversion of shigella flexneri type antigens was studied with the aid of wild-type and thermosensitive mutant phages. with all wild-type phages, the appearance of glycosylated antigen was accompanied by the appearance of polyprenyl phosphate glucose synthetase activity. with some of the mutant phages, the appearance of glycosylated antigen was not followed by the formation of lipid-linked glucose in the enzyme assay. the reverse has also been observed, i.e., the high rate of formation ... | 1976 | 793990 |
| [comparative susceptibility of animals to sonne and flexner dysentery]. | 1976 | 794642 |