Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| use of plasmid profile typing for surveillance of salmonella enteritidis phage type 4 from humans, poultry and eggs. | plasmids were found in 1022 of 1089 (94%) of drug-sensitive strains of salmonella enteritidis phage type 4 from humans (sporadic and outbreak cases), poultry (chickens) and eggs in england and wales in the 5-year period 1988-92 and 25 plasmid profile patterns were identified. strains characterized by a single plasmid of 38 mda predominated (= plasmid profile type se 38), comprising over 90% of isolates from humans, 70% from poultry and 92% from eggs. eleven profile types were identified in strai ... | 1994 | 8119362 |
| ten-year follow-up of 50 patients with bulimia nervosa. | long-term outcome studies for people suffering from bulimia nervosa are few. ten years after presentation, we followed up 50 patients (49 women, 1 man) who were originally involved in a double-blind, controlled trial of the antidepressant mianserin. standardised interviews and questionnaires were used to assess eating attitudes and behaviour, psychiatric status and social functioning. a dsm-iii-r diagnosis was given where appropriate. sufficient information to make a diagnosis was obtained for 4 ... | 1994 | 8137114 |
| influenza and meningococcal disease. | 1994 | 7903753 | |
| parvovirus b19 outbreak on an adult ward. | in november and december 1992, an outbreak of parvovirus b19 infection occurred among patients and staff on an adult mixed surgical ward at a large hospital in london. three patients and 15 staff members were serologically confirmed as acute cases. the attack rate among susceptible members of staff was 47%. in those infected, arthralgia (80%) and rash (67%) were the most common symptoms. of six susceptible in-patients on the ward, three became infected. one of the in-patients who had carcinoma o ... | 1994 | 7925671 |
| sequence similarity of human caliciviruses and small round structured viruses. | the application of reverse transcription-polymerase chain reaction (rt-pcr) using primers directed to the rna dependent rna polymerase region within orf1 of norwalk virus (nv) showed that 31 percent of morphologically typical human caliciviruses (hucv) and 57% of small round structured viruses (srsvs) produced a product of 470 bp similar to the nv control, nv 8fiia/68/us. alignment of the amino acid sequences of morphologically typical hucvs with previously published sequences for srsvs, nv, and ... | 1994 | 7931187 |
| asylum and the protection of human rights. | there are now some 18.5 million refugees in the world, many more displaced persons within their own country, and the number in both groups is steadily increasing. some of the problems of seeking asylum and providing the resources for the individual needs of displaced persons are considered. small non-governmental agencies such as the ockenden venture have a degree of flexibility which is particularly helpful. the increasing reluctance of all countries to offer asylum makes work in the displaced ... | 1994 | 7935169 |
| regular partners and risky behaviour: why do gay men have unprotected intercourse? | studies in both the uk and the usa continue to show that gay and bisexual men put themselves at risk of exposure to hiv through unprotected intercourse, most often with regular partners. as part of a larger study of homosexually active men, 310 men who had had unprotected anal intercourse with a man in the previous year were asked to describe the last occasion on which this had happened. the majority of men had had unprotected intercourse with a regular partner and did not perceived it as risky, ... | 1994 | 7948089 |
| a 10 year survey of the epidemiology and clinical aspects of listeriosis in a provincial english city. | between january 1983 and december 1992 29 cases of human listeriosis were recorded in bristol, giving an incidence for the decade of 0.35 infections/10(5) population/annum. for those less than a year old the incidence was 5.2/10(5) population/annum and for adults increased from 0.029/10(5)/annum for those aged 20-49 years to 0.65/10(5)/annum for those over 80 years of age. social classes i and ii were over represented in those infected while classes iv and v were under represented when compared ... | 1994 | 7963642 |
| molecules, management and medical outcomes: an international review. | the first major joint conference between the royal college of physicians of london and the american college of physicians was held at the royal college of physicians on 7-8 june 1993. the large enthusiastic audience from the uk and the usa demonstrated the cordiality which exists between the two colleges. the objective of the conference was to further an exchange of ideas about the influence of science and technology upon current and future medical practice. four major areas were chosen for revi ... | 1994 | 7965978 |
| ectoparasite control on sheep farms in england and wales: the method, type and timing of insecticidal treatment. | the chemical control of sheep ectoparasites raises important environmental, health and welfare issues. there is increasing concern about the possible harmful effects of pesticides on human health and the role of dipping in the contamination of natural watercourses. a longitudinal survey was conducted in 1991, the last year of compulsory dipping for the control of sheep scab, to obtain information about the chemical control of ectoparasites on 485 farms in england and wales. organophosphate insec ... | 1994 | 7975072 |
| natural history of trisomy 13. | the poor prognosis of patients with trisomy 13 has long been accepted and has been ascribed to brain and heart malformations. it has been suggested, however, that the long term survival is better than was previously thought and that cardiac surgery may be justified. this population based study reviews the incidence, antenatal diagnosis, spectrum of survival from congenital heart disease, and mode of death for patients with trisomy 13 in the northern health region from 1985 to 1992. there was an ... | 1994 | 7979530 |
| fluoride profiles in different surfaces of human permanent molar enamels from a naturally fluoridated and a non-fluoridated area. | the surfaces, sites and depths of fluoride profiles of enamel from a naturally fluoridated area (west hartlepool, whp, 1.9 parts/10(6) f in drinking water) and a non-fluoridated area (leeds, lds, < 0.1 parts/10(6) f in drinking water) were examined in detail. using a regression curve, y = ax-b, comparisons of fluoride concentrations were made at depths of 1, 3, 5, 10, 20 and 30 microns at occlusal, middle and cervical sites of buccal, lingual, mesial and distal molar enamel surfaces. in the oute ... | 1994 | 7980123 |
| evaluation of an antenatal hiv testing programme in an inner london health district. | to study an antenatal human immunodeficiency virus (hiv) testing programme in an inner london health district. | 1994 | 7999726 |
| local research ethics committees. widely differing responses to a national survey protocol. | the diversity in responses of local research ethics committees (lrecs) is illustrated with reference to consideration of the protocols for a national survey of physical activity, fitness and health in healthy volunteers. the survey included a questionnaire administered in the home, followed by a physical appraisal carried out in a mobile laboratory. the study was eventually approved by the 30 local committees to which it was submitted, but there was marked variation in the type of enquiries rece ... | 1994 | 8006869 |
| the complete sequence of a human astrovirus. | we have determined the complete genomic sequence of human astrovirus serotype 1 isolated in newcastle upon tyne. the genome is 6813 nucleotides long and contains three sequential open reading frames (orfs). the two closest to the 5' end are linked by a ribosomal frameshifting motif and contain sequence motifs indicative of non-structural virus proteins: serine protease and rna-dependent rna polymerase. a nuclear addressing sequence is also located here. the 3' orf encodes the virion structural p ... | 1994 | 8021608 |
| comparison of the effect of fluoride and non-fluoride toothpaste on tooth wear in vitro and the influence of enamel fluoride concentration and hardness of enamel. | the effect of the presence of fluoride in toothpaste on tooth wear was investigated in extracted human premolar teeth collected from two geographic areas with different fluoride concentrations in the public water supply. nine teeth from each area were divided bucco-lingually into matched pairs and subjected to a wear regime in vitro. the regime consisted of 5 minutes immersion in 6% citric acid buffered at ph 3.5, followed by 200 cycles of linear tooth-brushing in a slurry of either a fluoride o ... | 1994 | 8024870 |
| uptake of influenza vaccine. epidemic of 1989-90 improved uptake. | 1994 | 8038652 | |
| apparent increase in the prevalence of herpes simplex virus type 1 genital infections among women. | 1994 | 8039792 | |
| guilty of perpetuating the myth that john hunter suffered from syphilis after inoculating himself from a chancre. | 1994 | 8042337 | |
| the occurrence and seasonal changes in the isolation of listeria spp. in shop bought food stuffs, human faeces, sewage and soil from urban sources. | eight hundred and twenty-two shop-bought food specimens, 136 soil and 692 faecal specimens were cultured for listeria spp. in a regular, year round survey. 19.7% (162/822) of the foods, 93.9% (108/115) of the sewage, 14.7% (20/136) soils and 1% (7/692) of faeces yielded listeria spp. with 10.5% foods, 60.0% sewage, 0.7% soils and 0.6% faeces containing l. monocytogenes. no seasonal variation was noted in isolates from either sewage or foods, with l. monocytogenes and l. innocua being the commone ... | 1994 | 8043351 |
| respiratory symptoms and dust exposure in lancashire cotton and man-made fiber mill operatives. | a cross-sectional study of work-related symptoms and cotton dust exposure was made in 404 man-made fiber and 1,048 cotton operatives in lancashire spinning mills; 39 cotton-exposed operatives (3.7%) had symptoms of byssinosis. this was associated on regression analysis with cumulative lifetime cotton dust exposure (p < 0.001), total years spent carding (p < 0.001), and currently working in the carding area (p = 0.0041). smoking habit did not differ significantly between byssinotic and nonbyssino ... | 1994 | 8049827 |
| domino heart transplantation: the papworth experience. | the use of donor hearts from heart-lung recipients, the so-called domino procedure, began at papworth hospital in november 1988. between then and september 1992, 198 heart transplantations and 86 heart-lung transplantations were performed. fifty-three heart-lung recipients donated their hearts for use in the domino procedure. thirty-two domino hearts were transplanted at papworth and 21 were exported to other centers. institution of the domino procedure allowed us to perform 19% more heart trans ... | 1994 | 8061019 |
| epidemiology of genital herpes. | new serological methods, based on the detection of type-specific antibodies to herpes simplex virus (hsv) glycoproteins, have allowed a reappraisal of the prevalence of genital herpes. during the 1980s, genital herpes continued to be an infection of epidemic proportions in many developed countries. in the usa, although there was evidence of a decline in the age-specific prevalence of hsv type 1 (hsv-1) infection, the seroprevalence of hsv type 2 (hsv-2) has continued to increase. among those att ... | 1994 | 8063020 |
| zoonotic aspects of mycobacterium bovis infection. | the bovine tuberculosis eradication campaigns in many industrially developed countries have led to a huge reduction in the incidence of human tuberculosis caused by mycobacterium bovis. overt disease in man may, however, manifest decades after the initial infection and the occurrence of such disease raises several important questions. in particular, it is important to determine whether man-to-man transmission occurs, thereby rendering man a continuing reservoir of infection, and whether, if this ... | 1994 | 8073621 |
| social, behavioural and medical factors in the aetiology of testicular cancer: results from the uk study. uk testicular cancer study group. | although many risk factors have been proposed for the aetiology of testicular cancer, only a history of cryptorchidism is well established. all risk factors previously suggested have been explored in this study. this population-based case-control study was carried out in nine health regions in england and wales and included 794 men, aged 15-49 years, diagnosed with a testicular germ cell tumour between 1 january 1984 and 30 september 1986, each with an individually age-matched control. cases and ... | 1994 | 8080739 |
| identification of adenoviruses in faeces from patients with diarrhoea at the hospitals for sick children, london, 1989-1992. | faecal samples from 137 patients that had been shown to contain adenoviruses by electron microscopy were identified in a series of enzyme immunoassays (eia) using a single monoclonal antibody (mab) to adenovirus 40 and four different mabs to adenovirus 41. adenoviruses were partially characterised by restriction enzyme analysis (rea) of dna extracts using smai. samples were also run in a commercial eia (adenovirus ideia; dako, ltd.) which detects group antigen. the majority (84%) of adenoviruses ... | 1994 | 8083654 |
| seroprevalence of antibodies to human herpesviruses in england and hong kong. | the age-related prevalence of antibodies to herpesviruses was compared in england and hong kong. altogether 327 sera from england and 266 sera from hong kong were tested for antibodies to herpes simplex virus (hsv), varicella-zoster virus (vzv), epstein-barr virus (ebv), cytomegalovirus (cmv), and human herpesvirus 6 (hhv-6). herpesvirus infections were common in both countries but generally were acquired earlier and were more prevalent in hong kong. over 90% of children in hong kong were infect ... | 1994 | 8083655 |
| establishment of human tissue banks. | mounting interest in europe over the incorporation of the human biological model in the laboratory has been fuelled by scientific advances and the much improved accessibility to human tissue. the collection of tissue is complicated by a host of ethical considerations and lack of public awareness of the benefits of donation to research and education. in the united states, the international institute for the advancement of medicine (iiam) has been successful in networking the cooperation of organ ... | 1994 | 8086227 |
| associations between human and farm animal infections with salmonella typhimurium dt104 in herefordshire. | reports of human infection with salmonella typhimurium definitive type (dt) 104 have generated considerable interest. we undertook a descriptive study of infections with s. typhimurium dt 104 infection in humans and farm animals in herefordshire between 1991 and 1993. laboratory reports of human salmonellosis, sent to the consultant in communicable disease control, were compared with cases identified using statutory incident reports of salmonella in animals, birds and their products, received fr ... | 1994 | 7787923 |
| high prevalence of herpes simplex virus type 1 in female anogenital herpes simplex in newcastle upon tyne 1983-92. | this retrospective study was undertaken to evaluate the prevalence of the viral types and temporal epidemiology in patients with ano-genital herpes between 1983-92. one thousand one hundred and thirty-five patients with anogenital herpes were available for analysis. the annual incidence of anogenital herpes nearly tripled over the period of 7 years (1986-92) from 59 to 171 cases. the percentage of hsv-1 infection in female cases (63-79%) was much higher than in other reported studies and remaine ... | 1994 | 7819356 |
| sartorial eloquence: does it exist in the paediatrician-patient relationship? | to evaluate children's and parents' perceptions of hospital doctors' attire. | 1994 | 7819997 |
| iga antibodies in human milk: epidemiological markers of previous infections? | the concept of an enteromammary link in secretory iga (siga) antibody production was tested by hypothesising that specific siga antibody profiles in human milk might be an epidemiological marker for enteropathogens in a community. milk from three subject groups was studied: 64 sri lankan women living in poor suburbs of colombo, 20 asian immigrant women domiciled in birmingham, for a median period of five years (range 14 days-16 years), and 75 white women living in birmingham. an enzyme linked im ... | 1994 | 7820715 |
| mechanisms modifying glucose oxidation in diabetes mellitus. | the glucose fatty acid cycle as formulated 30 years ago and reviewed in the minkowski lecture in 1966 described short term effects of fatty acids (minutes) to decrease uptake, glycolysis and oxidation of glucose in heart and skeletal muscles. such short term effects have since been extended to include inhibition of glucose uptake and glycolysis and stimulation of gluconeogenesis in liver and these effects have also been convincingly demonstrated in man in vivo. more recently a longer term effect ... | 1994 | 7821731 |
| introduction to pandemic influenza through history. | for the past 400 years, epidemics resembling influenza have been recorded in many countries. epidemics from as early as the 16th century in england and the 18th century in the usa are recognizable as influenza, even in the absences of precise knowledge of their causative agents. | 1994 | 7843353 |
| a mathematical model for the european spread of influenza. | following a study modelling the geographical spread of influenza in france, on the basis of population movements through the use of railroad data, we applied the same methodology on a european scale. we simulated an epidemic within a network of 9 european cities (amsterdam, berlin, budapest, copenhagen, london, madrid, milano, paris, stockholm), only taking into account regular between-cities air transport. transportation data were obtained from the international civil aviation organization (199 ... | 1994 | 7843359 |
| the prediction of epidemics of respiratory infection. | experience from 25 years of clinical monitoring of influenza and related illnesses has been considered in relation to the prediction of epidemics of influenza. the monitoring has taken place in a network of sentinel practices in england and wales who report new episodes of illness weekly as they occur. the practice data are aggregated at the birmingham research unit of the royal college of general practitioners and weekly rates per 100,000 population are published in age-specific groups. major e ... | 1994 | 7843362 |
| surveillance of influenza in the united kingdom. pandemic and interpandemic period. | in the united kingdom the morbidity surveillance is carried out by the general practitioner spotter practice schemes (rcgp), the medical officers of schools association (mosa) and the emergency bed service. mortality data is provided weekly by the office of population and censuses and surveys (opcs). phls communicable disease surveillance centre (cdsc) collects all information and publishes the findings weekly in the communicable disease report (cdr). there are 53 public health laboratories situ ... | 1994 | 7843366 |
| john hunter and the natural history of the human teeth: dentistry, digestion, and the living principle. | 1994 | 7844341 | |
| clinical practice and the perceived importance of identifying high risk patients. | the royal free nhs trust is implementing a universal precautions policy for blood and body fluids. anticipating the introduction of this policy, a questionnaire was sent to a sample of staff and students who work with patients or clinical specimens. the questionnaire covered: views about identifying 'high risk' patients and specimens; perceived risks of human immunodeficiency virus (hiv) and hepatitis b infection from blood exposures; and current practices to avoid exposure to blood. over half t ... | 1994 | 7844346 |
| sequence conservation of the major outer capsid glycoprotein of human group c rotaviruses. | several outbreaks of group c rotavirus infection have occurred in the united kingdom, in one instance infection was associated with the death of a 4-month-old infant in the bristol area. the origin of human group c rotavirus is unknown although there has been some speculation that porcine species may be a possible source of human infection. direct reverse transcription-polymerase chain reaction sequencing of vp7 genes from two uk outbreaks (bristol and preston) and sequence analysis from a spora ... | 1994 | 7852957 |
| the "makyng" and re-making of man: 1. mary shelley's frankenstein, and transplant surgery. | 1994 | 7853300 | |
| the makyng and re-making of man: 2. mary shelley, or, the modern pandora, and gene therapy. | 1994 | 7853301 | |
| antibody to herpes simplex virus type 2 as serological marker of sexual lifestyle in populations. | to examine the epidemiology of antibody to herpes simplex virus type 2 and to assess its suitability as a serological marker of sexual behaviour in populations with high and low prevalences. | 1994 | 7866079 |
| practice nurses: characteristics, workload and training needs. | this study set out to identify the present and future training needs of practice nurses in south west thames regional health authority and to examine these needs within the nurses' current and changing workloads and social, educational and occupational profiles. | 1994 | 8312031 |
| salivary diagnosis of measles: a study of notified cases in the united kingdom, 1991-3. | to validate a method for salivary diagnosis of measles and to assess the diagnostic accuracy of notified cases of measles. | 1994 | 8167513 |
| british family heart study: its design and method, and prevalence of cardiovascular risk factors. family heart study group. | the aim of this paper is to describe the prevalence of cardiovascular risk factors in families screened systematically by nurses in british general practice, and in subgroups with reported hypertension, hypercholesterolaemia, diabetes and coronary heart disease. | 1994 | 8179948 |
| palaeoanthropology. time for boxgrove man. | 1994 | 8183361 | |
| a hominid tibia from middle pleistocene sediments at boxgrove, uk. | fossil hominids from the earlier middle pleistocene of europe are very rare and the mauer mandible is generally accepted as the most ancient, with an estimated age of 500 kyr. we report here on the discovery of a human tibia, in association with stone tools, from calcareous silts at the lower palaeolithic site of boxgrove, west sussex, uk (fig. 1). the silt units are correlated by mammalian biostratigraphy to an, as yet unnamed, major temperate stage or interglacial that immediately pre-dates th ... | 1994 | 8183368 |
| england's oldest human bone steps out. | 1994 | 8191277 | |
| sir henry thompson bt, the first english urologist. | sir henry thompson was a gifted victorian. as a surgeon he achieved early recognition by successfully removing king leopold of belgium's bladder stone where two other eminent surgeons had failed. he was undoubtedly the most famous surgeon of his age, a position he was to occupy for some 30 years. as well as professional eminence he achieved success in an extraordinarily wide range of endeavours. he was an accomplished artist, exhibiting 12 times at the royal academy, a connoisseur and collector ... | 1994 | 8199818 |
| re-evaluation of a radiation protection cost benefit analysis study in brachytherapy. | cost benefit analysis has been in use for many years as a method for making a comparison between the costs of radiation protection and the benefits of reduced radiation exposure. it is advocated by the international commission on radiological protection (icrp) and the national radiological protection board (nrpb) has given more specific advice relating to the value of the man sv to be used in the calculation of cost benefit. the purpose of this study is to investigate the changes in the nrpb adv ... | 1994 | 8298876 |
| prenatal exposure to influenza and the development of schizophrenia: is the effect confined to females? | the question of whether prenatal exposure to influenza epidemics is associated with an increased risk of later schizophrenia remains controversial. the authors examined this relationship, using data on the dates of birth and gender of 3,827 schizophrenic patients born in england and wales between 1938 and 1965 and first admitted to hospitals in the 1980s, the numbers of live births between 1938 and 1965, and the numbers of deaths attributed to influenza between 1937 and 1965. the analysis showed ... | 1994 | 8267108 |
| the socio-economic impact of human salmonella enteritidis infection. | recent government and public concern about the recorded increase in human salmonellosis in the uk and abroad has stimulated investigations of both the causes and consequences of these infections. this paper discusses the framework for economic analysis of food-borne disease and problems associated with the estimation of costs. a brief review of the literature in this area is given and the results of a national study of the costs of human salmonellosis in england and wales are presented and used ... | 1994 | 8155469 |
| seroprevalence studies using a recombinant norwalk virus protein enzyme immunoassay. | a recombinant norwalk virus (nv) protein enzyme immunoassay was used to study the age of acquisition of nv igg in various populations. in london, england, there was little evidence of infection during the first 2 years of life. however, the prevalence of nv igg rose steadily throughout the period that children attend school, reaching a peak of 70% in the group aged 11-16 years. high levels of maternal antibody were detected in infants aged < 3 months. comparison of the acquisition of antibodies ... | 1994 | 8158109 |
| fettler's disease with smoke inhalation: particles within the lung. | in august 1985, a 72-year-old man died in the manchester air disaster. transmission electron microscopy of his lung tissue revealed not only inhaled smoke particles, but a large population of distinctive particles with different characteristics. these contain silicon and iron, as well as carbon and oxygen, and are thought to be related to his occupation as a fettler and to the extensive fibrosis seen on routine histology. | 1994 | 8159076 |
| genetic linkage of cone-rod retinal dystrophy to chromosome 19q and evidence for segregation distortion. | inherited retinal dystrophies are the most common cause of childhood blindness in the developed world. cone-rod retinal dystrophies are severe examples of this group of disorders. analysis of a large cone-rod dystrophy pedigree suggested that inheritance within the family was influenced by meiotic drive (p = 0.008), a rare segregation distortion in human genetics. two-point linkage analysis showed significant linkage with three markers mapping to chromosome 19q. multipoint analysis gave a maximu ... | 1994 | 8162077 |
| the development of cimetidine: 1964-1976. a human story. | there was still controversy regarding the physiology of acid secretion in 1964 when a team at smith kline & french laboratories in england started a project to prove the existence of more than one receptor for histamine and to find a substance capable of blocking the effects not blocked by the commonly used antihistamines. the team was convinced that histamine was the final mediator of acid secretion. after 8 years, james black and his coworkers published evidence of the first histamine2-recepto ... | 1994 | 7806839 |
| [the man behind the bankart injury. he introduced a new technique for shoulder joint dislocation]. | 1994 | 7808109 | |
| hepatitis a antibodies in attenders of london travel clinics: cost-benefit of screening prior to hepatitis a immunisation. | the seroprevalence of hepatitis a antibodies in travellers attending london travel clinics increases with age and screening may eliminate the need for vaccination at present for approximately 40% of adults. the duration of protection by current hepatitis a vaccine(s) is still to be established. | 1994 | 7897370 |
| modern management of genital warts in women. | genital warts are common and are a sexually transmitted disease affecting all socioeconomic groups and life-styles. they are caused by the human papillomavirus (hpv) and are highly contagious. genital warts are often symptomless, but occasionally cause itching, bleeding after intercourse burning and pain. referral to a genitourinary medicine clinic is recommended, where specialist treatment and counselling are available. special care is needed with children or if the patient is pregnant. at the ... | 1994 | 8680165 |
| influenza and respiratory syncytial virus surveillance. | 1994 | 8640280 | |
| borrelia burgdorferi infection in uk horses. | antibody levels (igg and igm) to borrelia burgdorferi were measured in the sera and synovial fluids of uk horses. western blotting against b. burgdorferi was also used on samples from seropositive horses. a low incidence of seropositivity was shown in horses from most parts of the uk. this increased in areas that have a high incidence of human and canine borreliosis (norfolk and south coast). leptospira infections of horses did not cause cross reactions in the b. burgdorferi elisa. most horses d ... | 1994 | 8542836 |
| implementation of an antenatal serum screening programme for down's syndrome in two districts (brighton and eastbourne). the brighton and eastbourne down's syndrome screening group. | to evaluate the introduction to two health districts of an antenatal serum screening programme for down's syndrome using the triple test-measurement of alpha fetoprotein, unconjugated oestriol, and human chorionic gonadotrophin concentrations in second trimester serum samples. | 1994 | 8790485 |
| uk cervical cancer screening programme: setting a research agenda. | the uk national cervical cancer screening programme aims at reducing the incidence of and mortality from carcinoma of the cervix. it is generally agreed that high grade cervical intraepithelial neoplasia should be treated aggressively, but the appropriate management strategies for women with lesser degrees of abnormality are uncertain because of the inability to distinguish lesions that are likely to progress to invasive disease from those that will regress spontaneously. the role of human papil ... | 1994 | 8790530 |
| management ... working day of a health services manager. north staffordshire hospital. | physiotherapy needs to change to be relevant and appropriate to the delivery of health care in the future: departments in acute units will become smaller as therapists' expertise is required in the community. sue jackson, physiotherapy manager, north staffordshire hospital, describes the first steps in this culture change--and other professional and human resource issues. | 1994 | 10133762 |
| john coakley lettsom and "the highest and most divine profession, that can engage human intellect". | 1994 | 9156154 | |
| the regulation of assisted conception in england. | 1994 | 11654549 | |
| abortion: a constitutional problem in european perspective. | 1994 | 11656792 | |
| towards a standard application form for lrecs. | 1994 | 11653107 | |
| court allows second man the right to die. | 1994 | 11644511 | |
| re-thinking skilled international labour migration: world cities and banking organisations. | "highly skilled professional and managerial labour migration has become an important facet of the contemporary world economy. the operations of transnational corporations have created more opportunities for skilled migrants to work abroad.... there is a growing interest amongst economic geographers to examine this form of migration through an appreciation of global economic restructuring, labour market change and world cities. consequently, this paper introduces a new conceptual framework...[whi ... | 1994 | 12320415 |
| migration and social change: a longitudinal study of the social mobility of 'immigrants' in england and wales. | "data from the opcs longitudinal study is used to examine the social mobility of 'immigrants' in england and wales between 1971 and 1981. three issues are raised: (i) in what respects and to what degree do 'immigrants' differ in their social mobility characteristics from the norm set by the population as a whole?; (ii) in what respects and to what degree do 'immigrants' differ amongst themselves in their social mobility characteristics according to their country of origin?; and (iii) how do 'sec ... | 1995 | 12291075 |
| response to the human fertilisation and embryology authority's consultation document on research and fertility treatment using human ova and ovarian tissue obtained from live women, cadavers or fetuses. | 1995 | 11660189 | |
| police service in victorian and edwardian london: a somwhat atypical case of a hazardous occupation. | british society in the nineteenth century showed a growing concern with public-health issues and with occupational hazards. police service, which is at the centre of this paper, was not viewed by many as a hazardous occupation. using the london metropolitan police as a case study, the paper suggests that working conditions in the victorian and edwardian police had detrimental effects on the health of officers. it is true that medical statistics of the time showed that police officers in london h ... | 1995 | 11609064 |
| every child a perfect child? | 1995 | 11656466 | |
| bristol study continues to cause debate. | 1995 | 11654278 | |
| screening for down's syndrome: the first two years experience in bristol. | to evaluate the effectiveness of a programme for antenatal screening for down's syndrome using alpha fetoprotein and total human chorionic gonadotrophin as maternal serum markers. | 1995 | 8719150 |
| a prospective study of primary and secondary risk factor management in stroke patients. | stroke is a common event which often results in death or major loss of independence with immense human and financial costs, so identification of patients at risk, and prevention of stroke at the individual and population levels, is a high clinical and health priority. from august 1993 to july 1994, 468 stroke patients admitted to our hospital were assessed for the presence of stroke risk factors. all patients were followed up in hospital, and on discharge or death all hospital records were revie ... | 1995 | 8748104 |
| understanding adverse events: human factors. | (1) human rather than technical failures now represent the greatest threat to complex and potentially hazardous systems. this includes healthcare systems. (2) managing the human risks will never be 100% effective. human fallibility can be moderated, but it cannot be eliminated. (3) different error types have different underlying mechanisms, occur in different parts of the organisation, and require different methods of risk management. the basic distinctions are between: slips, lapses, trips, and ... | 1995 | 10151618 |
| information in general medical practice: a qualitative approach. | the aims of the study reported here were to describe the information-related behavior of general medical practitioners, to study information communication in general practices, and to establish guidelines for good practice. general practitioners (gps) were interviewed, and information and communication audits also involving other staff at the practices were undertaken. the main reasons why gps needed information were for patient care, managing the practice, legal and ethical matters, and teachin ... | 1995 | 10152474 |
| health care in the courts. r v cambridge district health authority. | 1995 | 10184446 | |
| the detailed human geography of britain. | "this article contains eight cartograms which help to provide answers to a variety of social and demographic questions about modern britain. how english is england? how is the pattern of birth-places changing? is there a north-south divide in the nation's health? are the inner cities less healthy than rural areas? has the changing pattern of unemployment eroded the economic divide between north and south? how do the various political, social and demographic patterns of modern britain relate to ... | 1995 | 12347655 |
| role of re-screening of cervical smears in internal quality control. | to investigate the use of rapid re-screening as a quality control method for previously screened cervical slides; to compare this method with 10% random re-screening and clinically indicated double screening. | 1995 | 8543619 |
| the development of healthcare services for drug misusers and prostitutes. | with the advent of human immunodeficiency virus (hiv) and the increase of drug misuse in the uk, the government wishes primary care to play a greater part in treating drug problems in the hope of preventing the spread of hiv. drug misusers do not avail themselves of traditional services and many are not registered with general practitioners. in response to this liverpool health authority and family health service authority commenced a new salaried post to provide primary care services to special ... | 1995 | 8545287 |
| conflicting attitudes to corneal and organ donation: a study of nurses' attitudes to organ donation. | the demand for transplantable organs and tissues is steadily increasing and action is necessary to improve the organ and tissue donation rates. previous research has suggested that nurses have a substantial influence on the rates of donation in the clinical area. nurses (n = 150) were asked to complete a number of measures to assess positive and negative attitudes towards cadaveric organ donation, with 112 (74.6%) responding. the findings identified conflicting attitudes particularly in relation ... | 1995 | 8550308 |
| influenza types and patient population. | 1995 | 8551864 | |
| influenza surveillance in england and wales: october 1994 to june 1995. | this report summarises the information obtained by surveillance of influenza in england and wales from october 1994 to june 1995 (weeks 40/94 to 25/95). influenza b viruses were responsible for most infections, with moderate activity occurring throughout the winter, peaking in february. influenza a became more active towards the end of the winter, and laboratory reports reached a peak in may (week 21/95). influenza activity was seen first in wales, then england, followed by scotland. an increase ... | 1995 | 8556105 |
| genetic studies on atopy and asthma in wessex. | 1995 | 8590326 | |
| evaluation of a breaking bad news course for medical students. | this paper presents the evaluation of a breaking bad news course run for three groups of medical students (fourth and fifth year from the london hospital medical college and fourth year from st bartholomew's hospital medical college). the course, which is student centred, uses group discussion, videotape presentations and role-play including actors. all teachers, clinicians and human science tutors, had been through a staff training programme on teaching methods. at the end of the course, studen ... | 1995 | 8594407 |
| practices and policies for influenza immunization in old people's homes in nottingham (uk) during the 1992-1993 season: potential for improvement. | the elderly residents of nursing and old people's homes are at substantially increased risk from influenza and its complications. annual vaccination is therefore strongly recommended by the uk departments of health. however, few data exist on the uptake of influenza vaccine in this setting; this was last estimated to be 45 percent in 1988-1989. a major epidemic of influenza a occurred in 1989-1990 which may have changed vaccination behaviours. | 1995 | 8639337 |
| from the centers for disease control and prevention. update: influenza activity--1995-96 season. | 1995 | 8568974 | |
| changes needed to law on mental incapacity. | 1995 | 7898188 | |
| dna repair, sry gene share jeantet prizes. | 1995 | 7816119 | |
| acceptability of shared care for asymptomatic hiv-positive patients. | in britain, human immunodeficiency virus (hiv) disease has been seen as an illness requiring specialist hospital care at all times. however, as its chronic nature has become apparent, the possibiliity that it could be managed more cost effectively in primary care has been raised. this has led to increasing interest in 'shared care', that is, care which is shared between a general practitioner and a specialist according to clear protocols, for this group of patients. however, for 'shared care' to ... | 1995 | 8536834 |
| detection of the poor metabolizer-associated cyp2d6(d) gene deletion allele by long-pcr technology. | the cytochrome p450 enzyme debrisoquine 4-hydroxylase metabolizes many different classes of commonly used drugs, such as antidepressants and neuroleptics. deficient hydroxylation of debrisoquine, known as the poor metabolizer (pm) phenotype, affects 5-10% of caucasians and may lead to adverse reactions upon administration of drugs in standard doses. this autosomal recessive metabolic deficiency is caused by the possession of two pm-associated mutations in the human cyp2d6 gene locus coding for t ... | 1995 | 8528268 |
| hiv and the boundaries of confidentiality. | confidentiality is an acknowledged duty of the nurse. it has foundations in ethics and has some legal force. there is also a more disingenuous reason for citing it as a duty: that it helps a group attain professional status. this may cause an over-zealous attitude towards confidentiality in some professionals. there are legal and ethical limits to confidentiality which can be seen clearly in cases which arise out of human immunodeficiency virus (hiv). whilst these make it clear that there are li ... | 1995 | 7897069 |
| schizophrenia risk for women from in utero exposure to influenza. | 1995 | 7802110 | |
| involvement of multiple cryptococcus neoformans strains in a single episode of cryptococcosis and reinfection with novel strains in recurrent infection demonstrated by random amplification of polymorphic dna and dna fingerprinting. | we compared the abilities of random amplification of polymorphic dna and dna fingerprinting, with oligonucleotide probes, to type five pairs of cryptococcus neoformans clinical isolates recovered from five separate human immunodeficiency virus-positive patients in london, england. the two techniques had comparable discriminatory abilities when applied to these isolates. a total of eight different isolate types were demonstrated in these patients. no isolate type was observed in more than one pat ... | 1995 | 7699075 |
| presence of secretory iga antibodies to an enteric bacterial pathogen in human milk and saliva. | the concept of a common mucosal immune system in man was tested by examining the concurrent presence of specific-secretory iga (siga) antibodies in human milk and saliva from three groups of subjects: 64 sri lankan women living in sri lanka; 20 immigrant asian women living in birmingham (median duration of residence in the united kingdom five years); and 75 caucasian women living in birmingham (controls). enzyme linked immunosorbent assays (elisa) were developed to detect enterotoxigenic escheri ... | 1995 | 7712266 |
| man behind the instrument (12). auacestus, joll cecil (1885-1945). | 1995 | 7718994 |