Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| bacteriological examination of the abdominal effusion in bacterial peritonitis. | this study provides a contemporary epidemiology of aspirates taken during surgery from the abdominal cavity among patients with bacterial peritonitis to identify the isolates and study their sensitivity to antibiotics. our bacteriology investigations included isolation of poor cultures, and detection of microbes was conducted using a rapid identification system (api20e, api staph, api strep, api ana, biomerieux). rapid tests for detection of oxidase and catalase activity were also used. suscepti ... | 2016 | 27770528 |
| increased enterococcus faecalis infection is associated with clinically active crohn disease. | this study was performed to investigate the relationship between the abundance of pathogenic gut microbes in chinese patients with inflammatory bowel disease (ibd) and disease severity.we collected clinical data and fecal samples from 47 therapy-naive chinese patients with ulcerative colitis (uc), 67 patients with crohn disease (cd), and 48 healthy volunteers. bacteria levels of fusobacterium species (spp), enterotoxigenic bacteroides fragilis (b fragilis), enteropathogenic escherichia coli (e c ... | 2016 | 27684872 |
| can surgical need in patients with naja atra (taiwan or chinese cobra) envenomation be predicted in the emergency department? | to investigate the clinical predictors and the aetiologies for surgery in patients with naja atra (taiwan or chinese cobra) envenomation. | 2016 | 27516567 |
| gut microbiota imbalance and colorectal cancer. | the gut microbiota acts as a real organ. the symbiotic interactions between resident micro-organisms and the digestive tract highly contribute to maintain the gut homeostasis. however, alterations to the microbiome caused by environmental changes (e.g., infection, diet and/or lifestyle) can disturb this symbiotic relationship and promote disease, such as inflammatory bowel diseases and cancer. colorectal cancer is a complex association of tumoral cells, non-neoplastic cells and a large amount of ... | 2016 | 26811603 |
| the making and taking of lipids: the role of bacterial lipid synthesis and the harnessing of host lipids in bacterial pathogenesis. | in order to survive environmental stressors, including those induced by growth in the human host, bacterial pathogens will adjust their membrane physiology accordingly. these physiological changes also include the use of host-derived lipids to alter their own membranes and feed central metabolic pathways. within the host, the pathogen is exposed to many stressful stimuli. a resulting adaptation is for pathogens to scavenge the host environment for readily available lipid sources. the pathogen ta ... | 2016 | 27720012 |
| effect of united states buckwheat honey on antibiotic-resistant hospital acquired pathogens. | due to an upsurge in antibiotic-resistant infections and lack of therapeutic options, new approaches are needed for treatment. honey may be one such potential therapeutic option. we investigated the susceptibility of hospital acquired pathogens to four honeys from wisconsin, united states, and then determined if the antibacterial effect of each honey against these pathogens is primarily due to the high sugar content. | 2016 | 28292167 |
| epidemiology of multidrug resistant bacterial organisms and clostridium difficile in german hospitals in 2014: results from a nationwide one-day point prevalence of 329 german hospitals. | one important aspect in combatting resistance to antibiotics is to increase the awareness and knowledge by epidemiological studies. we therefore conducted a german-wide point-prevalence survey for multidrug resistant bacterial organisms (mdros) and clostridium difficile (cd) to assess the epidemiology and structure quality of infection control in german hospitals. | 2016 | 27590879 |
| prebiotics and age, but not probiotics affect the transformation of 2-amino-3-methyl-3h-imidazo[4,5-f]quinoline (iq) by fecal microbiota - an in vitro study. | heterocyclic aromatic amines (haas) are carcinogens which are formed in meat cooked using high-temperature methods. the human gastrointestinal (gi) microbiota plays a crucial role in maintaining health in humans of different ages, and especially in the elderly. however, the gi microbiota, whose metabolism and composition changes with age, may also be responsible for the activation of mutagenic substances reaching the colon with diet. probiotics and prebiotics are promising in terms of reducing t ... | 2016 | 27034248 |
| cesarean section changes neonatal gut colonization. | delivery by means of cesarean section has been associated with increased risk of childhood immune-mediated diseases, suggesting a role of early bacterial colonization patterns for immune maturation. | 2016 | 27045582 |
| analysis of polyphenolic compounds in extracts from leaves of some malus domestica cultivars: antiradical and antimicrobial analysis of these extracts. | in this study, methanol, ethyl acetate, water extracts, and precipitate were obtained from leaves of malus domestica cultivars: golden delicious, jonagold, elstar, ligol, and mutsu. antiradical activity of these extracts was measured using the abts(+∙) radical, and antimicrobial activity was measured with the disk-diffusion method. phenolic compounds were measured with the colorimetric method and identified with high performance liquid chromatography (hplc). the highest antiradical activity was ... | 2016 | 28097143 |
| new hydrazines with sulphonamidic structure: synthesis,characterization and biological activity. | infections caused by bacterial species are common in immunocompromised patients and carry significant treatment costs and mortality. the emerging resistance of microorganisms to some synthetic antimicrobial agents makes it necessary to continue the research for new antimicrobial drugs. | 2016 | 24505922 |
| dietary administration of probiotics to sows and/or their neonates improves the reproductive performance, incidence of post-weaning diarrhea and histopathological parameters in the intestine of weaned piglets. | probiotics have gained considerable attention with respect to their beneficial effects on livestock performance and health. the most significant effects of probiotics on the gut microbiota and the host animals take place when they are included in diets during particularly stressful periods such as weaning and/or at the beginning of the lactation period. the probiotics bacillus mesentericus strain to-a at 1 × 10(8) colony forming units (cfu)/g, clostridium butyricum strain to-a at 1 × 10(8) cfu ... | 2016 | 27018090 |
| phenotypic and genotypic characterization of bacteriocinogenic enterococci against clostridium botulinum. | the present study aimed to characterize enterococcus faecalis (n = -6) and enterococcus faecium (n = 1) isolated from healthy chickens to find a novel perspective probiotic candidate that antagonize clostridium botulinum types a, b, d, and e. the isolated enterococci were characterized based on phenotypic properties, pcr, and matrix-assisted laser desorption/ionization time of flight (maldi-tof). the virulence determinants including hemolytic activity on blood agar, gelatinase activity, sensitiv ... | 2016 | 27914002 |
| malignant otitis externa in a healthy non-diabetic patient. | a healthy 60-year-old male was initially treated for external otitis, and subsequently received multiple surgeries including abscess drainage, temporal bone debridement, canaloplasty of the external auditory meatus, and fistula excision and was treated with numerous antibiotics at another hospital over a 1-year period. he was seen at our hospital on february 14, 2014 with a complaint of a non-healing wound behind the left ear and drainage of purulent fluid. he had no history of diabetes mellitus ... | 2016 | 26233245 |
| effects of enterococcus faecalis cect 7121 on cryptosporidium parvum infection in mice. | cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. however, there is a lack of completely efficient therapy available. probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. this study investigated the effects of administration of probiotic ent ... | 2016 | 27193238 |
| influence of a polymerizable eugenol derivative on the antibacterial activity and wettability of a resin composite for intracanal post cementation and core build-up restoration. | eugenol has been used in dentistry due to its ability to inhibit the growth of a range of microorganisms, including facultative anaerobes commonly isolated from infected root canals. the aim of this study was to evaluate the antibacterial activity of the experimental composites containing eugenyl methacrylate monomer (egma), a polymeric derivative of eugenol, against a range of oral bacteria, commonly associated with failure of coronal and endodontic restorations. in vitro composite behavior and ... | 2016 | 27130610 |
| bacteria in the apical root canals of teeth with apical periodontitis. | bacteria in the tooth root canal may cause apical periodontitis. this study examined the bacterial species present in the apical root canal of teeth with apical periodontitis. antibiotic sensitivity tests were performed to evaluate whether these identified bacterial species were susceptible to specific kinds of antibiotics. | 2016 | 27745799 |
| diversity of antibiotic resistance genes in enterococcus strains isolated from ready-to-eat meat products. | the objective of the study was to answer the question of whether the ready-to-eat meat products can pose indirect hazard for consumer health serving as reservoir of enterococcus strains harboring tetracyclines, aminoglycosides, and macrolides resistance genes. a total of 390 samples of ready-to-eat meat products were investigated. enterococcus strains were found in 74.1% of the samples. a total of 302 strains were classified as: enterococcus faecalis (48.7%), enterococcus faecium (39.7%), entero ... | 2016 | 27780292 |
| identification of vancomycin-susceptible major clones of clinical enterococcus from algeria. | the main objectives of this study were to characterize clinical strains of enterococcus spp. isolated from algerian inpatients and outpatients, to investigate their susceptibility to antibiotics and to analyse their phylogenetic relatedness. a total of 85 non-duplicate enterococcus spp. isolates collected between 2010 and 2013 from various clinical samples, including urine, vaginal swab, pus, blood and semen, from algerian inpatients (n=62) and outpatients (n=23) were identified using matrix-ass ... | 2016 | 27530845 |
| investigating bacterial population structure and dynamics in traditional koumiss from inner mongolia using single molecule real-time sequencing. | koumiss is considered as a complete dairy product high in nutrients and with medicinal properties. the bacterial communities involved in production of koumiss play a crucial role in the fermentation cycle. to reveal bacterial biodiversity in koumiss and the dynamics of succession in bacterial populations during fermentation, 22 samples were collected from 5 sampling sites and the full length of the 16s ribosomal rna genes sequenced using single molecule real-time sequencing technology. one hundr ... | 2016 | 27522429 |
| pitfalls in the identification of enterococcus species and the detection of vana and vanb genes. | the aims were to assess the performance of vitek 2 in identifying enterococcal species and the implementation of genexpert(®) vana/vanb pcr for the detection of vancomycin-resistant enterococci (vre). gram-positive cocci from clinical and environmental specimens (n = 431) suspicious of being enterococci by conventional methods were evaluated by vitek 2. this system identified 296 enterococcus faecium, 87 enterococcus faecalis, 10 enterococcus villorum, 9 enterococcus gallinarum, 9 enterococcus d ... | 2016 | 27367648 |
| macrolide, glycopeptide resistance and virulence genes in enterococcus species isolates from dairy cattle. | the genus enterococcus is known to possess the capacity to acquire and disseminate antimicrobial resistant determinants alongside the ability to produce various virulence genes that enables it to establish infections. we assessed the prevalence and antibiogram profiles of enterococcus spp. in faecal samples of dairy cattle. faecal swab samples were collected from 400 dairy cattle from two commercial cattle farms in two rural communities in the eastern cape, south africa. confirmation of enteroco ... | 2016 | 27166215 |
| antimicrobial resistance and virulence genes in enterococci from wild game meat in spain. | a total of 55 enterococci (45 enterococcus faecium, 7 enterococcus faecalis, and three enterococcus durans) isolated from the meat of wild game animals (roe deer, boar, rabbit, pheasant, and pigeon) in north-western spain were tested for susceptibility to 14 antimicrobials by the disc diffusion method. all strains showed a multi-resistant phenotype (resistance to between three and 10 antimicrobials). the strains exhibited high percentages of resistance to erythromycin (89.1%), tetracycline (67.3 ... | 2016 | 26678143 |
| microbial adhesion on novel yttria-stabilized tetragonal zirconia (y-tzp) implant surfaces with nitrogen-doped hydrogenated amorphous carbon (a-c:h:n) coatings. | biomaterial surfaces are at high risk for initial microbial colonization, persistence, and concomitant infection. the rationale of this study was to assess the initial adhesion on novel implant surfaces of enterococcus faecalis, staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, and candida albicans upon incubation. | 2016 | 26612401 |
| the structure-antimicrobial activity relationships of a promising class of the compounds containing the n-arylpiperazine scaffold. | this research was focused on in silico characterization and in vitro biological testing of the series of the compounds carrying a n-arylpiperazine moiety. the in silico investigation was based on the prediction of electronic, steric and lipohydrophilic features. the molecules were screened against mycobacterium avium subsp. paratuberculosis cit03, m. smegmatis atcc 700084, m. kansasii dsm 44162, m. marinum camp 5644, staphylococcus aureus atcc 29213, methicillin-resistant s. aureus 63718, escher ... | 2016 | 27681720 |
| [clinical analysis for patients with continuous ambulatory peritoneal dialysis associated peritonitis]. | to analyze the clinical characteristics of continuous ambulatory peritoneal dialysis (capd) associated peritonitis in the tertiary hospitals and to discuss the preventive and therapeutic strategy. methods: the clinical characteristics, pathogens, resistance and outcomes of 126 capd associated peritonitis in 104 patients from jan, 2013 to june, 2016, were retrospectively analyzed. results: among the patients, the incidence rates of abdominal pain, fever, diarrhea and emesis were 104 (82.54%), 5 ... | 2016 | 28070047 |
| antimicrobial and cytotoxicity evaluation of colloidal chitosan - silver nanoparticles - fluoride nanocomposites. | the present study aimed to evaluate the antimicrobial activity and cytotoxicity of colloidal chitosan - silver nanoparticle - fluoride nanocomposites (cchagnpfnc), with different silver nanoparticle shapes and sizes. the syntheses of cchagnpfnc were performed with silver nitrate added to a chitosan solution, addition of a sodium borohydride solution and solid sodium fluoride. solution of ascorbic acid was added to synthesize larger silver nanoparticles. cchagnpfnc obtained: s1- 100% spherical, 8 ... | 2016 | 27642129 |
| fabrication of antimicrobial silver-doped carbon structures by combinatorial pulsed laser deposition. | we report on the selection by combinatorial pulsed laser deposition of silver-doped carbon structures with reliable physical-chemical characteristics and high efficiency against microbial biofilms. the investigation of the films was performed by scanning electron microscopy, high resolution atomic force microscopy, energy dispersive x-ray spectroscopy, x-ray diffraction, raman spectroscopy, bonding strength "pull-out" tests, and surface energy measurements. in vitro biological assays were carrie ... | 2016 | 27773854 |
| antimicrobial metabolites from a marine-derived actinomycete in vietnam's east sea. | two new compounds, a quinoline alkaloid (1) and a 1,4-dioxane derivative (2), were isolated from culture broth of the marine-derived actinomycete micromonospora sp. (strain g019) by bioassay-guided fractionation. this actinomycete strain was isolated from sediment, collected at cát bà peninsula, vietnam. the taxonomic identification was achieved by analysis of 16s rrna gene sequences. on the basis of morphological and phylogenetic evidence, strain g019 was assigned to the genus micromonospora. t ... | 2016 | 26996018 |
| fibrinogen release and deposition on urinary catheters placed during urological procedures. | catheter associated urinary tract infections account for approximately 40% of all hospital acquired infections worldwide with more than 1 million cases diagnosed annually. recent data from a catheter associated urinary tract infection animal model has shown that inflammation induced by catheterization releases host fibrinogen, which accumulates on the catheter. further, enterococcus faecalis catheter colonization was found to depend on ebpa (endocarditis and biofilm-associated pilus), a fibrinog ... | 2016 | 26827873 |
| cloning and purification of the first termicin-like peptide from the cockroach eupolyphaga sinensis. | termicin is an antimicrobial peptide with six cysteines forming three disulfide bridges that was firstly isolated from the salivary glands and hemocytes of the termite pseudacanthotermes spiniger. in contrast to many broad-spectrum antimicrobial peptides, termicin is most active against filamentous fungi. although more than one hundred complementary dnas (cdnas) encoding termicin-like peptides have been reported to date, all these termicin-like peptides were obtained from isoptera insects. | 2016 | 26823660 |
| inhibition of bacterial and fungal pathogens by the orphaned drug auranofin. | we identified auranofin as an antimicrobial compound utilizing a high-throughput screen using a caenorhabditis elegans-staphylococcus aureus infection model. results/methodology: treatment of infected nematodes with auranofin resulted in a prolonged survival rate of 95%, reached with 0.78 μg/ml. further investigation of the antimicrobial activity of auranofin found inhibition against s. aureus, enterococcus faecium and enterococcus faecalis. importantly, the fungal pathogens cryptococcus neoform ... | 2016 | 26808006 |
| in vitro antimicrobial and anti-proliferative activities of plant extracts from spathodea campanulata, ficus bubu, and carica papaya. | african medicinal plants represent a prominent source of new active substances. in this context, three plants were selected for biological investigations based on their traditional uses. | 2016 | 26799575 |
| role of candida albicans secreted aspartyl protease sap9 in interkingdom biofilm formation. | the fungus candida albicans colonizes oral cavity surfaces and is carried by up to 60% of human populations. biofilm development by c. albicans may be modulated by oral streptococci, such as streptococcus gordonii, s. oralis or s. mutans, so as to augment pathogenicity. in this study we sought to determine if the cell wall-associated secreted aspartyl proteinase sap9 was necessary for hyphal adhesin functions associated with biofilm community development. a sap9δ mutant of c. albicans sc5314 for ... | 2016 | 26772652 |
| chemical composition and antimicrobial potential of palm leaf extracts from babaçu (attalea speciosa), buriti (mauritia flexuosa), and macaúba (acrocomia aculeata). | babaçu (a. speciosa), buriti (m. flexuosa), and macaúba (a. aculeata) are palm trees typical of the ecotone area between cerrado and the amazon rainforest. the purpose of this study was to evaluate the antimicrobial potential of the extracts prepared from the leaves of those palms as well as determine their chemical compositions. the ethanol extracts were prepared in a soxhlet apparatus and tested by disk diffusion and agar dilution technique against staphylococcus aureus, enterococcus faecalis, ... | 2016 | 27529077 |
| triterpenoids from acacia ataxacantha dc: antimicrobial and antioxidant activities. | acacia ataxacantha is a medicinal specie used extensively in traditional medicine of benin republic to treat infectious diseases. our previous study showed interesting antibacterial and antifungal activities against six strains of bacteria and six strains of fungi. the aim of this study was to investigate the antimicrobial and antioxidant activities of compounds isolated from a. ataxacantha. | 2016 | 27520306 |
| epizootiological characteristics of viable bacteria and fungi in indoor air from porcine, chicken, or bovine husbandry confinement buildings. | microorganisms found in bioaerosols from animal confinement buildings not only foster the risk of spreading diseases among livestock buildings, but also pose health hazards to farm workers and nearby residents. this study identified the various microorganisms present in the air of swine, chicken, and cattle farms with different kinds of ventilation conditions in korea. microbial air samples were collected onto petri dishes with bacterial or fungal growth media using a cascade impactor. endotoxin ... | 2016 | 27456779 |
| comparative evaluation of antimicrobial activity of qmix, 2.5% sodium hypochlorite, 2% chlorhexidine, guava leaf extract and aloevera extract against enterococcus faecalis and candida albicans - an in-vitro study. | debridement and disinfection of the root canal system is a critical step in endodontic treatment. most of the irrigants presently used in the endodontic treatment can have an impact on the microbes surviving in the biofilm but none of them are able to do all of the required tasks. researches are going on its full swing in order to produce an endodontic irrigant having ideal properties. | 2016 | 27437354 |
| novel benzimidazol-2-ylidene carbene precursors and their silver(i) complexes: potential antimicrobial agents. | novel benzimidazolium salts were synthesized as n-heterocyclic carbene (nhc) precursors, these nhc precursors were metallated with ag2o in dichloromethane at room temperature to give novel silver(i)-nhc complexes. structures of these benzimidazolium salts and silver(i)-nhc complexes were characterized on the basis of elemental analysis, (1)h nmr, (13)c nmr, ir and lc-ms spectroscopic techniques. a series of benzimidazolium salts and silver(i)-nhc complexes were tested against standard bacterial ... | 2016 | 27301680 |
| effect of electron-beam irradiation on antimicrobial, antibiofilm activity, and cytotoxicity of mouth rinses. | oral health diseases are common in all regions of the world. mouth rinses are widely used generally by population as a port of daily oral care regimen. in addition to antimicrobial activity, mouth rinses possess certain cytotoxic effects. electron-beam (e-beam) radiation is a form of ionizing energy known to induce structural, physical, and chemical changes in irradiated products. in this study, the modulatory effects of e-beam in irradiated mouth rinses were evaluated for its biological activit ... | 2016 | 27237203 |
| action of chlorhexidine, zingiber officinale, and calcium hydroxide on candida albicans, enterococcus faecalis, escherichia coli, and endotoxin in the root canals. | the purpose of this in vitro study was to evaluate the antimicrobial activity of 2% chlorhexidine gel (chx) as auxiliary chemical substance and intracanal medications on candida albicans, enterococcus faecalis, escherichia coli, and their endotoxins in the root canals. | 2016 | 27206998 |
| pregnane receptor gene polymorphisms, pathogenic bacteria distribution and drug sensitivity, and tcm syndrome differentiation in patients with cholelithiasis. | to investigate the distribution of pathogens and drug resistance in bile and the association between the pregnane x receptor (pxr) gene polymorphisms, traditional chinese medicine (tcm) syndromes and the risk of cholesterol gallstone disease (cgd). | 2016 | 27086146 |
| extracellular vesicle-derived protein from bifidobacterium longum alleviates food allergy through mast cell suppression. | the incidence of food allergies has increased dramatically during the last decade. recently, probiotics have been studied for the prevention and treatment of allergic disease. | 2016 | 26433560 |
| photoinactivation of eight health-relevant bacterial species: determining the importance of the exogenous indirect mechanism. | it is presently unknown to what extent the endogenous direct, endogenous indirect, and exogenous indirect mechanisms contribute to bacterial photoinactivation in natural surface waters. in this study, we investigated the importance of the exogenous indirect mechanism by conducting photoinactivation experiments with eight health-relevant bacterial species (bacteroides thetaiotaomicron, campylobacter jejuni, enterococcus faecalis, escherichia coli k12, e. coli o157:h7, salmonella enterica serovar ... | 2016 | 27121126 |
| microbial ecosystem analysis in root canal infections refractory to endodontic treatment. | the purpose of this study was to combine multiple displacement amplification and checkerboard dna-dna hybridization to qualitatively and quantitatively evaluate the microbiota present in infections refractory to endodontic treatment. | 2016 | 27377440 |
| 2-alkyl(aryl)-quinazolin-4(3h)-thiones, 2-r-(quinazolin-4(3h)-ylthio)carboxylic acids and amides: synthesis, molecular docking, antimicrobial and anticancer properties. | in this study, a series of novel 2-alkyl(aryl)-quinazolin-4(3h)-thiones, 2-r-(quinazolin-4(3h)-ylthio)carboxylic acids and amides were synthesized and evaluated for antimicrobial and anticancer activities. their structure was confirmed by elemental analysis and spectral data (ft-ir, lc-ms, (1)h-nmr). antimicrobial activity was tested in vitro against staphylococcus aureus, enterococcus faecalis, enterobacter aerogenes, pseudomonas aeruginosa, escherichia coli, klebsiella pneumonia, candida albic ... | 2016 | 25831026 |
| synthesis, characterization and antimicrobial activities of novel silver(i) complexes with coumarin substituted n-heterocyclic carbene ligands. | eight new coumarin substituted silver(i) n-heterocyclic carbene (nhc) complexes were synthesized by the interaction of the corresponding imidazolium or benzimidazolium chlorides and ag2o in dichloromethane at room temperature. structures of these complexes were established on the basis of elemental analysis, (1)h nmr, (13)c nmr, ir and mass spectroscopic techniques. the antimicrobial activities of carbene precursors and silver nhc complexes were tested against standard strains: enterococcus faec ... | 2016 | 26740157 |
| host-specific functional significance of caenorhabditis gut commensals. | the gut microbiota is an important contributor to host health and fitness. given its importance, microbiota composition should not be left to chance. however, what determines this composition is far from clear, with results supporting contributions of both environmental factors and host genetics. to gauge the relative contributions of host genetics and environment, specifically the microbial diversity, we characterized the gut microbiotas of caenorhabditis species spanning 200-300 million years ... | 2016 | 27799924 |
| characterization of antimicrobial substance from lactobacillus salivarius kl-d4 and its application as biopreservative for creamy filling. | lactobacillus salivarius kl-d4 isolated from duck intestine produced bacteriocin which was stable at high temperature and a wide ph range of 3-10. its cell free supernatant at ph 5.5 exhibited wide inhibitory spectrum against both g+ and g- bacteria. the highest bacteriocin production was obtained in mrs broth supplemented with 0.5 % (w/v) caco3 at 6 h by gentle shaking. pcr walking using specific primers at the conserved region of class-ii bacteriocin resulted in 4 known genes of kld1, kld2, kl ... | 2016 | 27462508 |
| burkholderia paludis sp. nov., an antibiotic-siderophore producing novel burkholderia cepacia complex species, isolated from malaysian tropical peat swamp soil. | a novel gram negative rod-shaped bacterium, designated strain msh1(t), was isolated from southeast pahang tropical peat swamp forest soil in malaysia and characterized using a polyphasic taxonomy approach. the predominant cellular fatty acids (>10.0%) were c16:0 (31.7%), c17:0 cyclo (26.6%), and c19:0 cyclo ω8c (16.1%). the polar lipids detected were phosphatidylglycerol, phosphatidylethanolamine, and diphosphatidylglycerol. the predominant ubiquinone was q-8. this revealed that strain msh1(t) b ... | 2016 | 28066367 |
| a novel mva-mediated pathway for isoprene production in engineered e. coli. | to deal with the increasingly severe energy crisis and environmental consequences, biofuels and biochemicals generated from renewable resources could serve as a promising alternative for replacing petroleum as a source of fuel and chemicals, among which isoprene (2-methyl-1,3-butadiene) in particular is of great significance in that it is an important platform chemical, which has been used in industrial production of synthetic rubber for tires and coatings or aviation fuel. | 2016 | 26786050 |
| anti-mrsa activities of enterocins dd28 and dd93 and evidences on their role in the inhibition of biofilm formation. | methicillin-resistant staphylococcus aureus (mrsa) has become a worrisome superbug. this work aimed at studying the effects of two class iib bacteriocins, enterocins dd28 and dd93 as anti-mrsa agents. thus, these bacteriocins were purified, from the cultures supernatants of enterococcus faecalis 28 and 93, using a simplified purification procedure consisting in a cation exchange chromatography and a reversed-phase high-performance liquid chromatography. the anti-staphylococcal activity was shown ... | 2016 | 27303396 |
| virb8-like protein trah is crucial for dna transfer in enterococcus faecalis. | untreatable bacterial infections caused by a perpetual increase of antibiotic resistant strains represent a serious threat to human healthcare in the 21(st) century. conjugative dna transfer is the most important mechanism for antibiotic resistance and virulence gene dissemination among bacteria and is mediated by a protein complex, known as type iv secretion system (t4ss). the core of the t4ss is a multiprotein complex that spans the bacterial envelope as a channel for macromolecular secretion. ... | 2016 | 27103580 |
| lipid composition in a strain of bacillus subtilis, a producer of iturin a lipopeptides that are active against uropathogenic bacteria. | urinary tract infections are a common disease in humans. therefore, new methods are needed to destroy biofilms that are formed by uropathogens. iturin a lipopeptides (lps) c14 and c15 are potent biosurfactants synthetized by the bacillus subtilis i'1a strain. the biological activity of extracted lps was confirmed by examining extracts from i'1a cultures against uropathogenic bacteria that had been isolated from biofilms on urinary catheters. compared with cultures of dsm 3257, which produce surf ... | 2016 | 27550437 |
| newer antibiotics for the treatment of peritoneal dialysis-related peritonitis. | peritonitis is a debilitating infectious complication of peritoneal dialysis (pd). drug-resistant bacterial peritonitis typically has a lower response rate to antibiotics. in the past 15 years, newer antibiotics with activities against drug-resistant gram-positive bacteria have been developed. in most circumstances, peritonitis due to methicillin-resistant staphylococci responds to vancomycin. if vancomycin cannot be used due to allergy and/or non-susceptibility, there is increasing evidence tha ... | 2016 | 27478608 |
| functional analysis of the citrate activator cito from enterococcus faecalis implicates a divalent metal in ligand binding. | the regulator of citrate metabolism, cito, from enterococcus faecalis belongs to the fcd family within the gntr superfamily. in the presence of citrate, cito binds to cis-acting sequences located upstream of the cit promoters inducing the expression of genes involved in citrate utilization. the quantification of the molecular binding affinities, performed by isothermal titration calorimetry (itc), indicated that cito has a high affinity for citrate (k d = 1.2 ± 0.2 μm), while it did not recogniz ... | 2016 | 26903980 |
| thusin, a novel two-component lantibiotic with potent antimicrobial activity against several gram-positive pathogens. | due to the rapidly increasing prevalence of multidrug-resistant bacterial strains, the need for new antimicrobial drugs to treat infections has become urgent. bacteriocins, which are antimicrobial peptides of bacterial origin, are considered potential alternatives to conventional antibiotics and have attracted widespread attention in recent years. among these bacteriocins, lantibiotics, especially two-component lantibiotics, exhibit potent antimicrobial activity against some clinically relevant ... | 2016 | 27486447 |
| discovery and analysis of natural-product compounds inhibiting protein synthesis in pseudomonas aeruginosa. | bacterial protein synthesis is the target for numerous natural and synthetic antibacterial agents. we have developed a poly(u) mrna-directed aminoacylation/translation (a/t) protein synthesis system composed of phenylalanyl-trna synthetases (phers), ribosomes, and ribosomal factors from pseudomonas aeruginosa this system has been used for high-throughput screening of a natural-compound library. assays were developed for each component of the system to ascertain the specific target of inhibitory ... | 2016 | 27246774 |
| composition and dynamics of the respiratory tract microbiome in intubated patients. | lower respiratory tract infection (lrti) is a major contributor to respiratory failure requiring intubation and mechanical ventilation. lrti also occurs during mechanical ventilation, increasing the morbidity and mortality of intubated patients. we sought to understand the dynamics of respiratory tract microbiota following intubation and the relationship between microbial community structure and infection. | 2016 | 26865050 |
| development of a novel test for simultaneous bacterial identification and antibiotic susceptibility. | background. elucidation of a pathogen's antimicrobial susceptibility requires subculture after the organism is first isolated. this takes several days, requiring patients to be treated with broad-spectrum antibiotics. this approach contributes to the development of bacterial resistance. methods. microtiter wells were coated with a polyclonal antibody targeting the pathogen of interest. bacterial suspensions were added in the presence/absence of selected antibiotics. after washing, captured bacte ... | 2016 | 27872553 |
| functional characterization of triclosan-resistant enoyl-acyl-carrier protein reductase (fabv) in pseudomonas aeruginosa. | pseudomonas aeruginosa is extremely resistant to triclosan. previous studies have shown that p. aeruginosa encodes a triclosan-resistant enoyl-acyl-carrier protein reductase (enr), fabv, and that deletion of fabv causes p. aeruginosa to be extremely sensitive to triclosan. in this report, we complemented a p. aeruginosa fabv deletion strain with several triclosan-resistant enr encoding genes, including vibrio cholerae fabv, bacillus subtilis fabl and enterococcus faecalis fabk. all complemented ... | 2016 | 27965638 |
| the essential oils of rhaponticum carthamoides hairy roots and roots of soil-grown plants: chemical composition and antimicrobial, anti-inflammatory, and antioxidant activities. | the essential oils were isolated by hydrodistillation from the hairy roots (hr) and roots of soil-grown plants (sgr) of rhaponticum carthamoides and were analyzed by gc-ms method. in the both essential oils 62 compounds were identified. the root essential oils showed the differences in the qualitative and quantitative composition. the sesquiterpene hydrocarbons (55-62%) dominated in both essential oils. the major compounds of hr essential oil were cyperene, 13-norcypera-1(5),11(12)-diene, and ca ... | 2016 | 28074117 |
| drug and vaccine development for the treatment and prevention of urinary tract infections. | urinary tract infections (uti) are among the most common bacterial infections in humans, affecting millions of people every year. uti cause significant morbidity in women throughout their lifespan, in infant boys, in older men, in individuals with underlying urinary tract abnormalities, and in those that require long-term urethral catheterization, such as patients with spinal cord injuries or incapacitated individuals living in nursing homes. serious sequelae include frequent recurrences, pyelon ... | 2016 | 26999391 |
| antimicrobial effects of silver nanoparticles stabilized in solution by sodium alginate. | to investigate the effect of nanosilver particles in solution stabilized in a matrix of sodium alginate on the growth and development of pathogenic bacteria such as staphylococcus aureus, enterococcus faecalis, escherichia coli, proteus vulgaris, enterobacter cloacae, the antibiotic-resistant strain of pseudomonas aeruginosa, the yeast-like fungus candida albicans, and the luminescent bacteria photobacterium leiognathi sh1. | 2016 | 27747311 |
| antimicrobial effect of ozone made by kp syringe of high-frequency ozone generator. | the aim of this study was to evaluate in vitro the antibacterial effect of ozone on suspension of three different bacteria inoculated in prepared canals of extracted human teeth. | 2016 | 27789911 |
| diversity of vaginal lactic acid bacterial microbiota in 15 algerian pregnant women with and without bacterial vaginosis by using culture independent method. | bacterial vaginosis (bv) is the most common lower genital tract disorder among women of reproductive age (pregnant and non-pregnant) and a better knowledge of lactobacillus species richness in healthy and infected vaginal microbiota is needed to efficiently design better probiotic products to promote the maintenance of normal flora which will help prevent bacterial vaginosis. | 2016 | 27790434 |
| anti-inflammatory and regenerative effects of albanian propolis in experimental vital amputations. | this study evaluated the effects of albanian propolis on the inflamed pulpal tissue after pulpotomy in piglets. in five piglets, two teeth each were infected using special pathogenic microbial flora that was prepared in advance in order to cause inflammation of the pulp. pulpotomy was performed in the maxillary and mandibular central and lateral incisors. microbial flora pathogenesis prepared from the section of infected teeth, containing staphylococcus aureus, streptococcus viridans, enterococc ... | 2016 | 28509506 |
| in vitro antimicrobial activity screening of xylaria hypoxylon. | fungi have a potential of using both as nutritive and medicinal food stuff. because of containing several therapeutic agents, they are reported to be used for hundreds of years to treat several diseases caused by bacteria, fungi, viruses and parasites. the aim of this study is to determine the in vitro antimicrobial activity of xylaria hypoxylon, which were collected from yomra, trabzon, turkey. | 2016 | 28852719 |
| integrating highly quantitative proteomics and genome-scale metabolic modeling to study ph adaptation in the human pathogen enterococcus faecalis. | genome-scale metabolic models represent the entirety of metabolic reactions of an organism based on the annotation of the respective genome. these models commonly allow all reactions to proceed concurrently, disregarding the fact that at no point all proteins will be present in a cell. the metabolic reaction space can be constrained to a more physiological state using experimentally obtained information on enzyme abundances. however, high-quality, genome-wide protein measurements have been chall ... | 2016 | 28725473 |
| the effect of gelatinase production of enterococcus faecalis on adhesion to dentin after irrigation with various endodontic irrigants. | objectives: the aim of this study was to evaluate whether the gelatinase production ability of enterococcus faecalis provides any advantage on adhesion of this bacterium to dentin treated with various irrigants and their combinations. materials and methods: standardized dentin discs were randomly divided into five groups (n = 20): group 1: 2.5% sodium hypochlorite (naocl), group 2: 2% chlorhexidine (chx), group 3: naocl + saline + chx, group 4: naocl + edta + naocl, group 5: qmix. after incubati ... | 2016 | 28642925 |
| microbiology of root canal infections. | inflammatory reaction in the periapical tissues is induced by microbial infection in the root canal system. the aim of root canal treatment is to preserve healthy periapical tissues or to provide healing of them in restorable teeth, which have sufficient periodontal support. the amount of microbial cells in the root canal system and their virulence as well as host responses influence on the degree of periapical inflammation and symptoms. microbial biofilm formation is typically seen on root cana ... | 2016 | 28826437 |
| synthesis and characterization of new chlorhexidine-containing nanoparticles for root canal disinfection. | root canal system disinfection is limited due to anatomical complexities. better delivery systems of antimicrobial agents are needed to ensure efficient bacteria eradication. the purpose of this study was to design chlorhexidine-containing nanoparticles that could steadily release the drug. the drug chlorhexidine was encapsulated in poly(ethylene glycol)-block-poly(l-lactide) (peg-b-pla) to synthesize bilayer nanoparticles. the encapsulation efficiency was determined through thermogravimetric an ... | 2016 | 28773576 |
| phenolic content, antibacterial and antioxidant activities of erica herbacea l. | antibacterial and antioxidant activity, total phenolic and flavonoid concentrations of aqueous, ethanol and ethyl acetate extracts from the leaves and flowers of erica herbacea l. were studied. in vitro antibacterial activity of the extracts was determined by macrodilution method. minimum inhibitory concentration (mic) and minimum bactericidal concentration (mbc) have been determined. testing was performed on 30 clinical isolates, including different strains of escherichia coli, enterococcus fae ... | 2016 | 24383325 |
| [multivalvular infective endocarditis with enterococcus faecalis]. | infective endocarditis (ie) is a relatively rare disease that can take part of sepsis and may be a diagnostic and therapeutic challenge. polyvalvular location of el is rare. we present a patient of 60 years diagnosed with plurivalvular infective endocarditis by enterococcus faecalis with septic complications, visceral, dragged, hospitalized for a psychiatric pathology, who raised the problems of diagnosis and treatment, without being able to make assessments on the entrance gate. for help in dia ... | 2016 | 23077930 |
| enterococcus faecium and enterococcus faecalis in blood of newborns with suspected nosocomial infection. | enterococci are gram-positive cocci saprophyte of the human gastrointestinal tract, diners who act as opportunistic pathogens. they can cause infections in patients hospitalized for a long time or who have received multiple antibiotic therapy. enterococcus faecalis and enterococcus faecium are the most common species in human infections. to evaluate the possibility of rapid detection of these species and their occurrence in the blood of newborns with suspected nosocomial infection, blood samples ... | 2017 | 24553613 |
| ex vivo microbial leakage after using different final irrigation regimens with chlorhexidine. | to assess the influence of final irrigation protocols with chlorhexidine in the coronal leakage of enterococcus faecalis in filled root canals. | 2017 | 23559116 |
| physicochemical characterization and antibacterial activity of rajata bhasma and silver nanoparticle. | bhasma, an ayurvedic metallo-mineral preparation, is claimed to be biologically produced nanoparticles. rajata (silver) is a noble metal known for its antimicrobial activity. rajata bhasma (rb) is expected to be composed of nanoparticles. with all these facts in place, this study was conducted to evaluate rb for the presence of silver nanoparticle (snp) and its antimicrobial effect. | 2017 | 28827959 |
| safety evaluation of enterocin producer enterococcus sp. strains isolated from traditional turkish cheeses. | the purpose of this study was to determine the antimicrobial activity and occurrence of bacteriocin structural genes in enterococcus spp. isolated from different cheeses and also investigate some of their virulence factors. enterococcus strains were isolated from 33 different cheeses. enterococcus faecium (6 strains) and enterococcus faecalis (5 strains) enterocin-producing strains were identified by 16s rdna analyses. structural genes enta, entb, entp and entx were detected in some isolates. mu ... | 2017 | 28735309 |
| isolation and characterization of lactic acid bacteria from traditional pickles of himachal pradesh, india. | a total of 15 isolates of lactic acid bacteria (lab) were isolated from traditional pickles of rural and urban areas of himachal pradesh. these isolates were identified as enterococcus faecalis (7), lactobacillus plantarum (3), pediococcus pentosaceus (2), leuconostoc mesenteroides (1), lactococcus lactis (1) and enterococcus sp. (1) on the basis of morphological, biochemical and 16s rdna sequence analysis. all the labs produced exopolysaccharides, have antibiotic susceptibility, and possess act ... | 2017 | 28720951 |
| inactivation of bacterial biofilms by visible light-activated unmodified zno nanorods. | various zinc oxide (zno) nanostructures are widely used for photocatalytic antibacterial applications. since zno possess a wide bandgap, it is believed that only uv light may efficiently assist bacterial inactivation and diverse crystal lattice modifications should be applied in order to narrow the bandgap for efficient visible light absorption. in this work we show that even unmodified zno nanorods grown by aqueous chemical growth technique were found to possess intrinsic defects which can be a ... | 2017 | 28628486 |
| characterization of high exopolysaccharide-producing lactobacillus strains isolated from mustard pickles for potential probiotic applications. | the aim of this study was to characterize high exopolysaccharide (eps)-producing lactic acid bacteria (lab) isolated from mustard pickles in taiwan for potential probiotic applications. among 39 collected lab strains, four most productive eps-producing strains were selected for further analysis. comparative analyses of 16s rdna genes rpoa and phes sequences demonstrated that these strains were members of lactobacillus plantarum-group (lpg). ncd 2, nld 4, slc 13, and nld 16 showed survival rates ... | 2017 | 28617525 |
| seven new lignan glycosides from the branches of alangium kurzii craib var. laxifolium. | seven new lignan glycosides (1-3, 8-10, and 14) and 17 known compounds were isolated from the branches of alangium kurzii craib var. laxifolium. their structures were established by spectroscopic analysis and circular dichroism (cd) and x-ray analysis. the isolated compounds were evaluated for their antibacterial activities against staphylococcus aureus ci1011, streptococcus suis ci1608, salmonella gallinarum ci0912, enterococcus faecalis ci1304, aeromonas hydrophila ci1008, escherichia coli ci1 ... | 2017 | 28733150 |
| in vitro selection and identification of potential probiotics isolated from the gastrointestinal tract of nile tilapia, oreochromis niloticus. | fish gut bacteria can be used as probiotics for aquaculture. the aim of this study is to screen and identify beneficial probiotic bacteria from the gut of nile tilapia, oreochromis niloticus. nine out of one hundred thirty-five isolates were non-pathogenic through intraperitoneal injection and had antibacterial activities with at least a strain from the five isolated fish pathogens, aeromonas sobria, aeromonas hydrophila, pseudomonas aeruginosa, pseudomonas putida, and staphylococcus aureus. fur ... | 2017 | 28819794 |
| induction of cryptic and bioactive metabolites through natural dietary components in an endophytic fungus colletotrichum gloeosporioides (penz.) sacc. | grape skin and turmeric extracts having the major components resveratrol and curcumin, respectively, were used for the induction of cryptic and bioactive metabolites in an endophytic fungus colletotrichum gloeosporioides isolated from syzygium cumini. the increase in total amount of crude compounds in grape skin and turmeric extract treated cultures was 272.48 and 174.32%, respectively, compared to the untreated control. among six human pathogenic bacteria tested, the maximum inhibitory activity ... | 2017 | 28674526 |
| the antibacterial and antifungal activity of six essential oils and their cyto/genotoxicity to human hel 12469 cells. | six essential oils (from oregano, thyme, clove, lavender, clary sage, and arborvitae) exhibited different antibacterial and antifungal properties. antimicrobial activity was shown against pathogenic (escherichia coli, salmonella typhimurium, yersinia enterocolitica, staphylococcus aureus, listeria monocytogenes, and enterococcus faecalis) and environmental bacteria (bacillus cereus, arthrobacter protophormiae, pseudomonas fragi) and fungi (chaetomium globosum, penicillium chrysogenum, cladospori ... | 2017 | 28811611 |
| phytochemical screening, antimicrobial and cytotoxicity studies of ethanol leaf extract of aphaniasenegalensis (sapindaceae). | aphania senegalensis (sapindaceae) is commonly used in senegalese traditional medicine to treat pain, inflammation, asthenia, bacterial and fungal infections. the aim of this study was to determine the type of phytochemical constituents present in the ethanol leaf extract and its antimicrobial activity against selected bacterial and fungal pathogens. | 2017 | 28638876 |
| antimicrobial and antioxidant activities of the extract and fractions of tetradenia riparia (hochst.) codd (lamiaceae) leaves from brazil. | tetradenia riparia (lamiaceae) is native to central africa popularly known as myrrh, used in folk medicine to treat various diseases like malaria, gastroenteritis, and tropical skin disease. this research was to evaluate the antioxidant and antibacterial activities of the crude extract (ce) and fractions (fr) of the t. riparia by classical chromatography. the ce of t. riparia leaves was submitted to column chromatographic fractionation to obtain four fractions of the interest, which were identif ... | 2017 | 28840299 |
| cyclohexene-fused 1,3-oxazines with selective antibacterial and antiparasitic action and low cytotoxic effects. | oxazine derivatives, a class of heterocyclic compounds, exhibit a variety of biological properties, such as anticonvulsant and antitumor activities. in this study, we evaluated the effect of two cyclohexene-fused 1,3-oxazines (cis‑1-benzyl-n-phenyl-1,4,4a,5,8,8a-hexahydro-3,1-benzoxazin-2-imine (1) and trans‑n-phenyl-1,4,4a,5,8,8a-hexahydro-3,1-benzoxazin-2-imine (2)) in cultures of bacillus cereus, enterococcus faecalis, escherichia coli, klebsiella pneumoniae, salmonella enterica, serratia mar ... | 2017 | 28755871 |
| detection of eight foodborne bacterial pathogens by oligonucleotide array hybridization. | simultaneous and rapid detection of multiple foodborne bacterial pathogens is important for the prevention of foodborne illnesses. | 2017 | 28713514 |
| high level bacterial contamination of secondary school students' mobile phones. | while contamination of mobile phones in the hospital has been found to be common in several studies, little information about bacterial abundance on phones used in the community is available. our aim was to quantitatively determine the bacterial contamination of secondary school students' mobile phones. | 2017 | 28626737 |
| self assembled snowball-like hybrid nanostructures comprising viburnum opulus l. extract and metal ions for antimicrobial and catalytic applications. | herein, we report the production of novel organic-inorganic nanobio-catalytic and antimicrobial agents called "nanosnowball" (nsbs) with a rational design and elucidate the increase in the catalytic and antimicrobial activities. the nsbs resemble to guelder rose were formed of the extract of viburnum opulus (vo) as the organic component and copper (ii) ions (cu(2+)) as the inorganic component. the effects of the vo extract and cu(2+) concentrations on the morphology of nsbs were systematically e ... | 2017 | 28465062 |
| use of whey as a culture medium for bacillus clausii for the production of protein hydrolysates with antimicrobial and antioxidant activity. | the use of whey as a natural culture medium to produce hydrolysates with antimicrobial from bacillus clausii is the objective of this research. the fermentation process was carried out at 25 ℃ for five days, where proteolytic activity, soluble peptides quantification, and antimicrobial activity using the disc diffusion method were determined every day. the fermented whey reached values of proteolytic activity between 90 and 260 u ml(-1) and a production of soluble peptides between 100 and 2070 ... | 2017 | 28816527 |
| growth inhibition and antibiofilm potential of ag nanoparticles coated with lectin, an arthropod immune molecule. | lectins from the haemolymph of arthropods, including crustaceans, are molecules potentially involved in the immune recognition and phagocytosis. here, lectin was purified from the haemolymph of blue swimmer crab portunus pelagicus, using mannose-coupled sepharose cl-4b affinity column chromatography. in sds-page analysis, lectin showed a molecular mass of approximately 155kda. the synthesis of lectin-coated silver nanoparticles (lectin-coated agnps) was confirmed by uv-vis spectroscopy, xrd, fti ... | 2017 | 28441606 |
| comparative evaluation of anti microbial effects of triple antibiotic paste and amox and its derivatives against e. faecalis: an in vitro study. | enterococcus faecalis is a microorganism commonly detected in asymptomatic, persistent endodontic infections. triple antibiotic paste has stood the test of time as a proven antibiotic combination against e. faecalis. however, problems with this include staining of teeth and standardization of the preparation. thus, the search for better alternatives and better preparation techniques is still on. | 2017 | 28638559 |
| antibacterial activity of different root canal sealers against enterococcus faecalis. | the aim of the present study was to compare in vitro the antimicrobial activity of different root canal sealers against enterococcus faecalis, prior and subsequent to setting. | 2017 | 28638549 |
| telavancin: a novel semisynthetic lipoglycopeptide agent to counter the challenge of resistant gram-positive pathogens. | telavancin (td-6424), a semisynthetic lipoglycopeptide vancomycin-derivative, is a novel antimicrobial agent developed by theravance for overcoming resistant gram-positive bacterial infections, specifically methicillin-resistant staphylococcus aureus (mrsa). the us food and drug administration (usfda) had approved telavancin in 2009 for the treatment of complicated skin and skin structure infections (csssis) caused by gram-positive bacteria, including mrsa (s. aureus, streptococcus agalactiae, s ... | 2017 | 28634536 |
| antibacterial activity of crude extracts of some south african medicinal plants against multidrug resistant etiological agents of diarrhoea. | this study evaluated the antibacterial activity of some plants used in folklore medicine to treat diarrhoea in the eastern cape province, south africa. | 2017 | 28629407 |
| molecular identification of multiple antibiotic resistant fish pathogenic enterococcus faecalis and their control by medicinal herbs. | the opportunistic fish pathogen, enterococcus faecalis has been reported to cause mass mortality in several fish species in different countries. the objectives of this study were to (i) identify e. faecalis from the diseased fishes through molecular techniques; (ii) assess the antibiotic susceptibility profile of e. faecalis isolates; and (iii) control disease in tilapia fish by treatment with medicinal plant extracts. a total of 48 isolates were phenotypically identified as enterococcus species ... | 2017 | 28623336 |
| bactericidal effect of er:yag laser-activated sodium hypochlorite irrigation against biofilms of enterococcus faecalis isolate from canal of root-filled teeth with periapical lesions. | this study was to evaluate the bactericidal effect of er:yag laser-activated sodium hypochlorite irrigation (er:yag + naocl) on biofilms of enterococcus faecalis clinical isolate. | 2017 | 28622484 |
| design, synthesis, and evaluation of novel tyrosine-based dna gyrase b inhibitors. | the discovery and synthesis of new tyrosine-based inhibitors of dna gyrase b (gyrb), which target its atpase subunit, is reported. twenty-four compounds were synthesized and evaluated for activity against dna gyrase and dna topoisomerase iv. the antibacterial properties of selected gyrb inhibitors were demonstrated by their activity against staphylococcus aureus and enterococcus faecalis in the low micromolar range. the most promising compounds, 8a and 13e, inhibited escherichia coli and s. aure ... | 2017 | 28621824 |