Publications

TitleAbstractYear(sorted ascending)
Filter
PMID
Filter
characterization and biological activities of two copper(ii) complexes with diethylenetriamine and 2,2'-bipyridine or 1,10-phenanthroline as ligands.two new mixed ligand copper(ii) complexes with diethylenetriamine, 2,2'-bipyridine and 1,10-phenanthroline have been synthesized. the crystal and molecular structures of [cu(dien)(phen)](clo(4))(2) and [cu(dien)(bipy)](bf(4))(2) (dien=diethylenetriamine, phen=1,10-phenanthroline, bipy=2,2'-bipyridine) were determined by x-ray crystallography from single crystal data. these two complexes have similar structures. the epr spectral data also suggest that these complexes have distorted square pyramid ...200516257723
outcome of bacterial culture from mastoid granulations: is it relevant in chronic ear disease?to detect the presence of bacteria in mastoid granulations and compare its prevalence in both types of chronic suppurative otitis media (csom). to find out if stage of disease activity, age, duration of disease, and aditus patency relate to obtaining positive cultures.200516259653
successfully treated mitral valve proteus mirabilis endocarditis.infective endocarditis caused by proteus mirabilis is rare and is fatal in most cases. a case of a 64-year-old man presenting with fever, dysuria, and murmur is reported. p mirabilis endocarditis was diagnosed based on clinical presentation, blood culture findings, and the presence of a large mitral valve vegetation seen on echocardiogram. the patient survived after long-term antibiotics and surgical replacement of the mitral valve. the clinical characteristics and complications from reported ca ...200515894870
organisms causing urinary tract infection in pediatric patients at ayub teaching hospital abbottabad.urinary tract infection (uti) is common in pediatric practice and an important cause of morbidity and mortality in children. infected urine stimulates an immunological and inflammatory response leading to renal injury and scarring, ultimately leading to end stage renal failure. the present study identifies the micro organisms causing urinary tract infection in children presenting with uti at ayub teaching hospital, abbottabad.200515929535
outbreaks of contaminated broncho-alveolar lavage related to intrinsically defective bronchoscopes.from 5 march 2001 to 19 october 2001, outbreaks of broncho-alveolar lavage (bal) contamination with enterobacteraceae were detected in our 700-bed institution. we report the investigation of these outbreaks. a case was defined as the occurrence of pairs of specific enterobacteraceae in bal specimens among any patients who underwent bronchoscopy in the respiratory unit during the period of the outbreak. contamination was identified in 117 bal samples during three outbreaks among 418 patients, and ...200515893850
structures of the o-polysaccharides and classification of proteus genomospecies 4, 5 and 6 into respective proteus serogroups.an acidic branched o-polysaccharide was isolated by mild acid degradation of the lipopolysaccharide (lps) of proteus genomospecies 4 and studied by sugar and methylation analyses along with 1h and 13c nmr spectroscopy, including 2d cosy, tocsy, roesy and h-detected 1h, 13c hsqc experiments. the following structure of the pentasaccharide repeating unit of the o-polysaccharide was established, which is unique among proteus polysaccharide structures: [structure: see text] where qui3nac stands for 3 ...200516262693
bacterial flora of the low male genital tract in patients consulting for infertility.the physiological aerobic bacterial flora of the low male genital tract was determined. this prospective study was performed on 600 semen specimens collected from 543 asymptomatic males consulting for infertility. semen cultures were sterile in 28.8%, with a polymicrobial flora and/or absence or low titres of ureaplasma urealyticum in 49.3%, and with one or two aerobic and facultative bacteria > or =1 x 10(3) cfu ml(-1) and/or u. urealyticum with titres > or =10(4) ccu ml(-1) (colour changing un ...200516266393
bacterial flora of leg ulcers in patients admitted to department of dermatology, poznań university of medical sciences, during the 1998-2002 period.venous leg ulcers are an important cause of morbidity in a significant percentage of the world population. the percentage of leg ulceration, either active or healed, in the european population is about 1%-2%. the aim of this study was to analyze the rate of colonization and qualitative composition of the bacterial flora isolated from leg ulcers in patients admitted to dermatology department, poznań university of medical sciences, during the 1998-2002 period, with special reference to the infecti ...200516146619
analysis of antibiotic susceptibility and resistance of leg ulcer bacterial flora in patients hospitalized at dermatology department, poznań university hospital.effective treatment of frequently infected, poorly healing wounds such as leg ulcers due to chronic venous insufficiency poses a major clinical problem. antibiotic resistance in dermatology patients, especially those with non-healing leg ulcers, is a widespread phenomenon. various antibiotics, mainly broad-spectrum agents, are frequently and sometimes inappropriately prescribed, which often leads to the selection of antibiotic-resistant bacteria strains. the aim of this study was to analyze anti ...200516146620
hemihyperplasia with ehlers-danlos syndrome like skin changes.hemihyperplasia is a condition characterized by asymmetric overgrowth of one or more body parts. it may be an isolated finding or may be associated with various syndromes like beckwith-weidemann syndrome, klippel-trenaunay-weber syndrome, proteus syndrome etc. pigmentary skin lesions and capillary malformations are commonly seen in cases of hemihyperplasia. we report a case of hemihyperplasia with associated skin hyperextensibility, varicose veins, skin fragility, easy bruising and papery scars, ...200516155424
genotyping of urinary and fecal proteus mirabilis isolates from individuals with long-term urinary catheters. 200516167137
influence of human ascitic fluid on the in vitro antibacterial activity of moxifloxacin.we investigated the in vitro influence of haf on the antibacterial activity of moxifloxacin against escherichia coli atcc 10798, escherichia coli k-12, proteus rettgeri (sanelli), staphylococcus aureus atcc 25923, staphylococcus aureus nctc 1808 and staphylococcus epidermidis atcc 12228. human ascitic fluid was obtained from 6 cirrhotic patients by paracentesis. the interaction effect was evaluated by the checkerboard technique. our results indicate the ability of human ascitic fluid to reduce m ...200516167519
bacteriology of surgical wound infections in a tertiary care hospital in turkey.to determine the spectrum of the pathogens cultured from surgical wound infections and assess their antimicrobial drug resistances.200516167704
in vitro and in vivo antibacterial activities of sm-216601, a new broad-spectrum parenteral carbapenem.sm-216601 is a novel parenteral 1beta-methylcarbapenem. in agar dilution susceptibility testing, the mic of sm-216601 for 90% of the methicillin-resistant staphylococcus aureus (mrsa) strains tested (mic(90)) was 2 microg/ml, which was comparable to those of vancomycin and linezolid. sm-216601 was also very potent against enterococcus faecium, including vancomycin-resistant strains (mic(90) = 8 microg/ml). sm-216601 exhibited potent activity against penicillin-resistant streptococcus pneumoniae, ...200516189097
granulomatous inflammation of salt glands in ducklings (anas platyrhynchos) associated with intralesional gram-negative bacteria.the "nasal glands" occur in many bird species and are powerful sodium ion-excretory organs. in ducks, they are located in supraorbital bony recesses. granulomatous inflammation of these glands occurs with an incidence of approximately 1% in ducklings (anas platyrhynchos), and is not associated with specific clinical symptoms. we investigated nine glands of eight animals with granulomas by gross pathology and histopathology, and compared results of bacteriology with 20 non-lesioned nasal glands. ...200516191707
bacteriological study of diabetic foot infections.the polymicrobial nature of diabetic foot infection has been well documented in the literature. patients with diabetic foot infection not exposed to antibiotics are not well studied before. the relative frequency of bacterial isolates cultured from community-acquired foot infections that are not exposed to antimicrobial agents for 30 days is studied. in addition, the bacterial comparative in vitro susceptibility to the commonly used antibacterial agents is assessed.200515866058
purple urine bag syndrome in a hemodialysis patient.purple urine bag syndrome (pubs) is an uncommon disorder, in which the plastic disposable urinary catheter bag turns purple or blue following hours or days of urinary catheterization. the purple discoloration results from indirubin dissolved in the plastic mixing with indigo in the urine. bacteria possessing indoxyl sulfatase degrade indoxyl sulfate into indirubin and indigo. indoxyl sulfate is derived from the metabolism of tryptophan. pubs usually occurs in chronic catheterized elderly women w ...200516157987
[efficacy of probiotic bactisporin in therapy of intrahospital urinary infection].we studied efficacy of bactisporin (probiotic based on aerobic spore-forming culture bacillus subtilis, strain 3h) in combined treatment of intrahospital urinary infection (iui) in 36 patients with infravesical obstruction. these patients developed postoperative complications due to iui caused by antibiotic-resistant hospital flora. the control group consisted of 35 patients matched by age and disease given conventional postoperative etiotropic therapy. bacterial translocation enables bactispori ...200516158748
anti-bacterial activity of euphorbia fusiformis--a rare medicinal herb.euphorbia fusiformis buch.-ham. ex. d.don (euphorbiaceae) is a rare medicinal herb. aqueous and organic solvent extracts of the leaves and rootstocks were investigated for anti-bacterial properties by using disc diffusion and well-in agar methods, against pathogenic strains of gram positive (bacillus subtilis and staphylococcus aureus) and gram negative bacteria (escherichia coli, klebsiella pneumoniae, proteus vulgaris, pseudomonas aeruginosa, salmonella typhii a and salmonella typhii b). the d ...200516159702
[surveillance of susceptibility of clinical isolates to cefmetazole between 2000 and 2003].for the post-marketing surveillance of cefmetazole (cmz, cefmetazon), mics of injectable beta-lactam antibacterials including cmz against clinical isolates from 15 medical institutions all over japan are measured yearly and the incidence rates of resistance in various species are also evaluated. in the first surveillance from june 2000 to march 2001, 574 isolates of 13 species were tested, 548 isolates of the same 13 species were tested in the second surveillance from april 2001 to march 2002, a ...200516161756
regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the asia-pacific region (sentry 1998-2002).we examined the prevalence of extended-spectrum beta-lactamase (esbl)-producing strains of klebsiella pneumoniae, klebsiella oxytoca, escherichia coli, proteus mirabilis, citrobacter koseri, and salmonella spp. that were isolated as part of the sentry asia-pacific surveillance program between 1998 and 2002. during the study period, a total of 6,388 strains were gathered from 17 medical centers in 7 countries and examined for esbl production and hyperproduction of k. oxytoca chromosomal k1 beta-l ...200516165001
fatal herpes simplex virus infection in darier disease under corticotherapy.a 67-year-old man is presented with longstanding and severe darier disease treated by topical antiseptics and potent corticosteroids, in combination with oral glucocorticoids and etretinate. after cardiac bypass surgery in 1997, the patient experienced herpes simplex virus (hsv type-1) infection of the skin that was treated by intravenous aciclovir. in 2003, he presented a widespread atypical exacerbation of his darier disease, involving the face, trunk, buttocks, intertriginous areas and arms. ...200516048763
isolation of bacteria with antibiotic resistance from household cockroaches (periplaneta americana and blattella germanica).cockroaches may harbor and disseminate microorganisms to the environment. in this study, periplaneta americana and blattella germanica were collected from 40 households in kaohsiung city and kaohsiung county, taiwan. cockroach infestation was found in 50% of the studied households and 226 cockroaches (123 p. americana and 103 b. germanica) collected by trapping. p. americana was more often found in the kitchen (70.7%) whereas b. germanica in the storage room (51.5%) and kitchen (36.9%). there wa ...200515716054
effects of lipopolysaccharides from gram-negative bacteria on the level of thiols in blood platelets.lipopolysaccharide (endotoxin, lps) activates blood platelets and stimulates generation of free radicals in these cells. the mechanism of platelet activation induced by lps is not known. the aim of the present study was to examine how glutathione (gsh) and other thiol-containing compounds are involved in the oxidative stress in blood platelets caused by lps. the hplc technique has been used on the analysis of non-protein thiols from human blood platelets treated with lipopolysaccharides of diffe ...200516049662
gudair (ojd) vaccine self-inoculation: a case for early debridement. 200516053420
surveillance of antimicrobial resistance in bulgaria--a synopsis from bulstar 2003.we introduce bulgarian surveillance tracking antimicrobial resistance (bulstar) and make the first report on surveillance data for 2003. this longitudinal surveillance programme monitors the isolation and antimicrobial susceptibility of all clinically significant microorganisms isolated from blood cultures, cerebrospinal fluid, upper and lower respiratory tract, urine and wound samples in the participating microbiology laboratories. twenty eight public, 45 hospital and 6 private laboratories fro ...200516077213
[design and improvement of an elective culture medium for bacteriological diagnosis of salmonella infection].experimental studies have provided a nutrient broth for elective accumulation of salmonella (ma broth) and a differential diagnostic culture medium for selective isolation of the causative agents of salmonella toxic infections. the ma broth is used for bacteriological isolation of salmonellae from the low-infected material and for a sanitary-and-bacteriological study of meat-and- sausage and other foods for this pathogen. a combination of high accumulating and inhibiting properties of the design ...200516078535
inhibitor-based methods for detection of plasmid-mediated ampc beta-lactamases in klebsiella spp., escherichia coli, and proteus mirabilis.non-beta-lactam inhibitor-based methods were evaluated for detecting plasmid-mediated ampc beta-lactamases in klebsiella spp., escherichia coli, and proteus mirabilis. using clsi methodology and disks containing cefotetan alone and in combination with 400 mug of boronic acid, 9 of 10 positive control strains and 54 of 55 ampc-pcr-positive clinical isolates were detected. importantly 71% and 40% of these clinical isolates were susceptible by routine testing to ceftriaxone and ceftazidime, respect ...200516081966
structure of the o-polysaccharide and serological studies of the lipopolysaccharide of proteus mirabilis 2002.the structure of the o-polysaccharide of the lipopolysaccharide of proteus mirabilis 2002 was elucidated by chemical methods and 1h and 13c nmr spectroscopy. it was found that the polysaccharide consists of branched pentasaccharide repeating units having the following structure: [structure in text]. the o-polysaccharide of p. mirabilis 2002 has a common tetrasaccharide fragment with that of p. mirabilis 52/57 from serogroup o29, and the lipopolysaccharides of the two strains are serologically re ...200516084933
elevated levels of igm and iga antibodies to proteus mirabilis and igm antibodies to escherichia coli are associated with early rheumatoid factor (rf)-positive rheumatoid arthritis.antibodies to proteus mirabilis were previously detected in patients with established rheumatoid arthritis (ra). we examined the prevalence of antibodies to p. mirabilis and their associations with ra in early synovitis patients.200516091399
rheumatoid arthritis and proteus. 200516138503
[antibiotic resistance: from the results of onerba's networks to good antibiotic use]. 200516144065
[bacterial flora and mycosis of the vagina in women with symptoms of vaginal inflammation].to estimate the microbiological profile of vaginal flora in 30 women with gynecologic problems and 20 pregnant women complaining about pathological symptoms {pruritus, burning, vaginal discharge}.200516145858
[prevalence of multidrug-resistant proteus spp. strains in clinical specimens and their susceptibility to antibiotics].proteus sp. are opportunistic microorganisms which cause urinary tract and wounds infections, bacteriaemia and sepsis. the aim of this study was analysis of prevalence of multidrug-resistant proteus sp. strains in clinical specimens and evaluation of their susceptibility to selected antibiotics. the study was carried out of 1499 proteus sp. strains were isolated in 2000-2003 from patients of departments and dispensaries of the university hospital cm in bydgoszcz umk in torun. the strains were id ...200516134389
[comparison of frequency and susceptibility to antimicrobials of bacterial strains of the family enterobacteriaceae isolated from patients hospitalised in intensive care units].the aim of the study was estimation of frequency and susceptibility to antimicrobial agents of gram-negative rods isolated from clinical specimens obtained from patients requiring intensive care, with emphasis on profile of the unit. the analysis comprised strains of gram-negative rods isolated from patients of two intensive care units (icus) of a tertiary care hospital (1200 beds). identification of cultured isolates was done using automated vitek and api systems (biomerieux, france). susceptib ...200516134390
[health accuracy of travnik cheese and quality standards of sanitary accuracy].the aim of work was to determine a health accuracy of sheep milk and the final product travnik cheese, as well as the quality standards of sanitary accuracy. the study was performed on 212 milk samples selected by random choice. the study involved observing the sanitary conditions of sheep milk and cheese production, as well as isolation and identification of causal agents of infective diseases in these products. the results showed the following agents isolated from milk and travnik cheese: esch ...200516134761
erythromycin synergism with essential and trace elements.in order to establish the role of various essential and trace element complexation on the antibacterial activity of various macrolide antibiotics, the synergistic or antagonistic behavior of erythromycin metal complexes have been studied and compared with the parent drug. metal complexes of erythromycin with magnesium, calcium, chromium, manganese, iron, cobalt, nickel, copper, zinc and cadmium have been investigated for their antibacterial activity and compared with erythromycin by observing th ...200516431396
phylogeny of the enterobacteriaceae based on genes encoding elongation factor tu and f-atpase beta-subunit.the phylogeny of enterobacterial species commonly found in clinical samples was analysed by comparing partial sequences of their elongation factor tu gene (tuf) and of their f-atpase beta-subunit gene (atpd). an 884 bp fragment for tuf and an 884 or 871 bp fragment for atpd were sequenced for 96 strains representing 78 species from 31 enterobacterial genera. the atpd sequence analysis exhibited an indel specific to pantoea and tatumella species, showing, for the first time, a tight phylogenetic ...200516166704
identification and antimicrobial susceptibility of micro-organisms recovered from cutaneous lesions of human american tegumentary leishmaniasis in minas gerais, brazil.an evaluation of the microbiota present in cutaneous ulcers from 31 patients with a clinical and parasitological diagnosis of american tegumentary leishmaniasis (atl) was carried out by the standard filter paper disc technique, including antimicrobial susceptibility of the bacterial isolates. microbial examination indicated that 21 patients (67.7%) were contaminated with one to four bacteria and some of them also with yeast. a total of 142 micro-organisms were isolated. staphylococcus aureus was ...200516192439
mechanical transmission of pathogenic organisms: the role of cockroaches.cockroaches (diploptera punctata) are basically tropical insects and will do their best to find a home that is both warm and moist. their involvement in the transmission of tropical diseases is poorly investigated in africa.200516457381
aerobic heterotrophic bacterial diversity in sediments of rajakkamangalam estuary, south west coast of india.the abundance of aerobic heterotrophic bacterial population in the sediment sample of six experimental stations (s1 to s6) at rajakkamangalam estuary was studied for a period of one year from march, 1998 to february, 1999. the important bacterial genera encountered were pseudomonas, bacillus, vibrio, escherichia, micrococcus, enterobacter, salmonella, aeromonas, shigella, klebsiella, proteus, alkaligenes, staphylococcus, citrobacter and flavobacterium. the bacterial population based on numerical ...200516459565
misdiagnosis of neurofibromatosis type 1 as proteus syndrome. 200516462730
increasing incidence of bacterial, resistance to antibiotics by isolates from the urinary tract.this is a prospective study to determine the prevalence of antibiotic resistance among organisms causing urinary tract infections in a teaching hospital between august 2003 and july 2004 and to compare them with an earlier study in 1993. a total of 1,104 urine samples were collected in sterile universal containers from patients attending university of nigeria teaching hospital and studied. all samples showing significant bacteriuna were studied and isolates identified using standard bacteriogica ...200516477864
microbiology of dacryocystitis among adults population in southern australia.retrospective study on microbiology of dacryocystitis cases in adults was carried out at the royal victorian eye and ear hospital (rveeh). sixty-four consecutive cases seen between march 2000 and june 2003 were included. seventy-nine organisms were isolated from the sixty-six samples (1.2/specimen). aerobic or facultative bacteria were recovered in 76 (96.2), fungi from two specimens (2.5%). and anaerobic bacteria from only one specimen (1.3%). staphylococcus aureus (27), was most common followe ...200516295714
a study of sensitivity and resistance of pathogenic micro organisms causing uti in kathmandu valley.a retrospective study was conducted in five hospitals to observe the prevalence of organisms causing uti and their sensitivity to antibiotics. methodology: altogether, data from five hundred samples of urine from five hospitals in kathmandu was collected for this study from january 2005 to april 2005. result: a total of 244 samples were found to be positive. altogether six types of organisms were isolated as the causative factors. e. coli (49%), s. aureus, (coagulase positive) (23%), proteus spe ...200516415607
[rare bacteria species found in wounds of tsunami patients. predominance of gram-negative rods, increased antibiotic resistance].microbiological cultures from 229 patients seeking medical advise in stockholm after the tsunami catastrophe december 2004 were analysed at the clinical microbiology laboratory, karolinska university hospital, stockholm, sweden. gram-negative rods were the most common findings from wound cultures. common human pathogens as escherichia coli, proteus species, klebsiella spp, and pseudomonas aeruginosa were isolated. however, more rare species of gram-negative rods were also isolated, e.g. myroides ...200516416946
lymphocytic colitis: a clue to bacterial etiology.to find out the role of bacteria as a possible etiological factor in lymphocytic colitis.200516437626
detection and identification of intestinal pathogenic bacteria by hybridization to oligonucleotide microarrays.to detect the common intestinal pathogenic bacteria quickly and accurately.200516437687
[evaluation of the antimicrobial potential of immune sera].the inhibiting activity of blood sera obtained from 20 volunteers immunized with the multi-component vaccine "pyopol", 25 nonimmune donors and 7 lots of human antistaphylococcal immunoglobulin with respect to staphylococcus aureus, escherichia coli, proteus vulgaris and pseudomonas aeruginosa has been studied in the liquid nutrient medium with the use an automated microbiological analyzer. the sera of donors immunized with the vaccine "pyopol" have been found to possess high antimicrobial activi ...200516438372
[influence of dendrite cells, generated with the use of immunomodulators of microbial origin, on the proliferative and cytotoxic activity of lymphocytes].the influence of ripe dendrite cells (dc) on the proliferative activity of mononuclear leukocytes and the cytotoxic activity of lymphocytes of syngenic mice was studied. as inducers of dc ripening, the combination of antigenic components incorporated into the vaccine "lmmunovac bh-4", (klebsiella pneumoniae, proteus vulgaris, escherichia coli, staphylococcus aureus), as well as k. pneumoniae lps and tnf-alpha, were used. this study demonstrated that dc activated with these preparations enhanced ...200516438373
windblown foot: a particular presentation of proteus syndrome? 200516440890
risk of nosocomial bacteria transmission: evaluation of cleaning methods of probes used for routine ultrasonography.there exists a small but definite risk of nosocomial infection transmission attributable to ultrasonography probes and coupling gels.200516092321
longitudinal trends in antimicrobial susceptibilities across long-term-care facilities: emergence of fluoroquinolone resistance.antibiotic resistance in the longterm-care facility (ltcf) setting is of increasing concern due to both the increased morbidity and mortality related to infections in this debilitated population and the potential for transfer of resistant organisms to other healthcare settings. longitudinal trends in antibiotic resistance in ltcfs have not been well described.200515693409
assessment of antibacterial activity of some topical otological solutions.otological solutions have long been used in the treatment of the bacterial and fungal infections of the ear. we investigated antibacterial activity of some otic solutions against the most common bacteria isolated from discharging ears.200516340276
antimicrobial activity of flavonoids from pelargonium radula (cav.) l'hérit.flavonoids from pelargonium radula (cav.) l'hérit were purified by column chromatography. two fractions were obtained: f1 (main flavonoid isoquercitrin) and f2 (main flavonoid rutin). in vitro antimicrobial activity of f1 and f2 were tested against eleven species of bacteria and eleven species of fungi. both fractions demonstrated strong inhibitory activity against staphylococcus aureus, proteus rettgeri, candida tropicalis and microsporum gypseum. staphylococcus sp. (coagulase-negative) and can ...200516375833
acute uncomplicated lower urinary tract infections in general practice: clinical and microbiological cure rates after three- versus five-day treatment with trimethoprim.epidemiological studies indicate that acute uncomplicated urinary tract infections (uti) in women can be successfully treated with short treatment regimens. however, the findings from the literature do not match experiences in daily practice.200516392777
unilateral proteus syndrome.proteus syndrome is a complex developmental abnormality. it is characterized by both hypertrophic and hypoplastic changes. deformities have been occasionally found to be localized in one half of the body in head or digit but presence of all signs in one half of the body in a wide spread manner is not reported in the literature. we report the case for its unusual presentation of unilateral localization of signs.200516394389
proteus syndrome.proteus syndrome is a variable and complex disorder characterized by multifocal overgrowths affecting any tissue or structure of the body. we present a girl aged 3 years and 8 months with an epidermal nevus, port-wine stain, macrodactyly with gigantism of the feet, lymphohemagiomas and multiple lipomas.200516394465
update on the molecular genetics of vascular anomalies.genetic factors play a critical role in the pathogenesis of vascular anomalies. significant advances have been made in recent years in identifying the genetic and molecular determinants of a variety of vascular anomalies using a molecular genetic approach. several genes for vascular anomalies have been identified. these genes include aggf1 for klippel-trenaunay syndrome, rasa1 for capillary malformations, krit1, mgc4607, pdcd10 for cerebral cavernous malformations, glomulin for glomuvenous malfo ...200516379592
[problems of epidemic safety of drinking water use by the population of russia].quantitative relationships were studied between the indicators (common coliform bacteria (ccp), glucose-positive bacteria (gpb), thermoduric bacteria (tdb), coliform bacteria, enterococci, clostridia, coliphages) and the opportunistic (pseudomonas aeruginosa, proteus, klebsiella) and pathogenetic (salmonella and intestinal viruses) microorganisms at the stages of effluent purification and decontamination, in processes of self-purification in the water reservoirs and of water preparation at water ...200516404875
comparative antimicrobial potency of meropenem tested against gram-negative bacilli: report from the mystic surveillance program in the united states (2004).the meropenem yearly susceptibility test information collection (mystic) program is a longitudinal resistance surveillance network of more than 100 medical centers worldwide monitoring the susceptibility of bacterial pathogens to carbapenems and other broad-spectrum agents. in 2004 (year six), the antimicrobial activity of 12 broad-spectrum agents was assessed against 2,799 gram-negative bacterial isolates submitted from 15 united states (usa) medical centers using clinical and laboratory standa ...200516323433
hsp60 expression during carcinogenesis: a molecular "proteus" of carcinogenesis? 200516333979
in-vitro antibacterial and cytotoxic activity of cobalt (ii), copper (ii), nickel (ii) and zinc (ii) complexes of the antibiotic drug cephalothin (keflin).keflin (kefl) interacts with co(ii), cu(ii), ni(ii) and zn(ii) metal ions leading to complexes of the type m(kefl)2cl2 and m(kefl)cl2, which have been characterized by physicochemical and spectroscopic methods. magnetic moment, ir, electronic spectral and elemental analyses data suggest that keflin behaves tridentately forming octahedral or trigonal bipyramidal complexes with the metal ions mentioned above. the new compounds have been screened in-vitro for antibacterial and cytotoxic activity ag ...200516335054
proteus syndrome with giant myelolipoma in the pelvis.proteus syndrome is a very rare and complex disorder with malformations and overgrowth of multiple tissues. this disorder was designated proteus syndrome by wiedemann et al. to denote its variable clinical expression. our patient presented with macrodactyly, cerebriform appearance and a huge abdominal mass. a biopsy under laparotomy was performed, and histopathological examination revealed myelolipoma. tumor resection was performed. to our knowledge, no case of proteus syndrome presenting a myel ...200516351661
determination of the antimicrobial properties of oligo-2-hydroxy-1-naphthaldehyde.oligo-2-hydroxy-1-naphthaldehyde (ohna) was synthesized by oxidative polycondensation using h2o2 (35%, aqueous solution), air o2 and naocl (34%, aqueous solution) by kaya and senol and the products were characterized by spectral techniques. antimicrobial activities of the first and second fractions of ohna were tested against corynobacterium xerosis ccm 2824, proteus vulgaris atcc 6897, staphylococcus epidermidis nrrl b-4877, s. aureus atcc 6538, enterobacter aerogenes atcc 13048, salmonella thy ...200516355978
in vitro activities of tigecycline, ertapenem, isepamicin, and other antimicrobial agents against clinically isolated organisms in taiwan.this study evaluated the in vitro activities of tigecycline, ertapenem, isepamicin, and other comparators against 861 bacterial isolates recovered from patients treated in three major teaching hospitals in 2003. mics to antimicrobial agents were determined by the agar dilution method. high rates of oxacillin resistance (58%) in staphylococcus aureus (60 isolates), and vancomycin resistance (21%) and quinupristin-dalfopristin non-susceptibility (39%) in enterococcus faecium (34 isolates) were fou ...200516359192
ctx-m-1 extended-spectrum beta-lactamase-producing proteus mirabilis in greece.to examine the dissemination of ctx-m-type extended-spectrum beta-lactamases (esbls) in clinical isolates of proteus mirabilis, 91 nonrepetitive esbl-producing p. mirabilis were collected from infected patients in a tertiary greek hospital during september, 2001, to may, 2004. a bla (ctx-m) gene was amplified in one isolate (strain a328), but bla (ctx-m) was not detected in any of the remaining esbl producers. sequencing results showed that p. mirabilis a328 produced a ctx-m-1 enzyme while pcr m ...200516359194
neurocutaneous syndromes and epilepsy-issues in diagnosis and management.epilepsy may be seen as a feature of many of the neurocutaneous syndromes. the challenge lies within the diagnosis of the specific disorder and ultimately control of the epilepsy. tuberous sclerosis is the most common of the disorders with a frequency of 4.9/100,000. an autosomal-dominant condition, diagnostic features may be unclear under 2 years of age. population studies suggest a prevalence of epilepsy of 78%, the majority presenting under the age of 12 months, with a high association betwee ...200516359466
effects of commercial diazinon and imidacloprid on microbial urease activity in soil and sod.diazinon [o,o-diethyl o-2-isopropyl-6-methyl(pyrimidine-4-yl) phosphorothioate] and imidacloprid [1-(1-[6-chloro-3-pyridinyl]methyl)-n-nitro-2-imidazolidinimine] are applied to lawns for insect control simultaneously with nitrogenous fertilizers such as urea, but their potential effect on urease activity and nitrogen availability in turfgrass management has not been evaluated. urease activity in enzyme assays, washed cell assays, and soil slurries was examined as a function of insecticide concen ...200516091610
the antimicrobial activity of extracts of the lichen hypogymnia tubulosa and its 3-hydroxyphysodic acid constituent.the antimicrobial activity and the mic values of the diethyl ether, acetone, chloroform, petroleum ether, and ethanol extracts of the lichen hypogymnia tubulosa and its 3-hydroxyphysodic acid constituent have been investigated against some microorganisms. at least one of the extracts or 3-hydroxyphysodic acid showed antimicrobial activity against aeromonas hydrophila, bacillus cereus, bacillus subtilis, escherichia coli, klebsiella pneumoniae, listeria monocytogenes, proteus vulgaris, salmonella ...200515787241
frequency and treatment of urinary tract infection in children subjected to urine culture, in sana'a, yemen.this study was carried out to estimate the frequency of urinary tract infection among children subjected to urine culture presenting to sam hospital, sana'a city, yemen and to determine the susceptibility of the isolated bacteria to the antibiotics.200516092643
an electrified catheter to resist encrustation by proteus mirabilis biofilm.we investigated the effect of iontophoresis produced by passing an electric current through silver electrodes attached to catheters on catheter encrustation by crystalline proteus mirabilis biofilm.200516094079
efficacy of dilute betadine solution irrigation in the prevention of postoperative infection of spinal surgery.prospective, single-blinded, randomized study.200516094267
proteus syndrome: a rare cause of hemihypertrophy and macrodactyly on bone scanning.proteus syndrome is a rare, sporadic genetic disorder characterized by overgrowth of multiple different tissues in a mosaic pattern. it is associated with connective tissue nevi, epidermal nevi, disproportionate overgrowth of multiple tissues, vascular malformations, characteristic tumors, and specific facial anomalies. joseph merrick, popularly known as the elephant man, is now believed to have suffered from proteus syndrome. a case of proteus syndrome and associated findings on bone scintigrap ...200516100477
[resistance of catheter-associated urinary tract infections to antibacterials].catheter-associated urinary tract infections (cauti) are the most common nosocomial infections. the worldwide data show the increasing resistance to conventional antibiotics among urinary tract pathogens.200515790045
incidental detection of purulent fluid in kidney at percutaneous nephrolithotomy for branched renal calculi.some patients undergoing percutaneous nephrolithotomy (pcnl) have purulent fluid in the pelvicaliceal system at the time of puncture, although preoperative features are not suggestive of infection. we report the management and outcome of 19 such patients.200515798405
potency and spectrum of tigecycline tested against an international collection of bacterial pathogens associated with skin and soft tissue infections (2000-2004).the antimicrobial activity of tigecycline, a novel glycylcycline, was evaluated against 5289 bacterial isolates recovered from hospitalized patients with skin and soft tissue infections during 2000-2004. strains were submitted from >70 medical centers in north america, latin america, and europe, and were tested centrally using reference broth microdilution methods. the top 10 ranking pathogens (95% of total) recovered included staphylococcus aureus (55.2%), enterococcus spp. (9.6%), pseudomonas ...200516105564
biochemical characterization of the chondroitinase abc i active site.cabc i (chondroitinase abc i) from proteus vulgaris is a galag (galactosaminoglycan) depolymerizing lyase that cleaves its substrates at the glycosidic bond via beta-elimination. cabc i cleaves a particularly broad range of galag substrates, including cs (chondroitin sulphate), ds (dermatan sulphate) and hyaluronic acid. we recently cloned and recombinantly expressed cabc i in escherichia coli, and completed a preliminary biochemical characterization of the enzyme. in the present study, we have ...200516108757
[weil-felix test]. 200516111212
a study on inhibitory effects of siğla tree (liquidambar orientalis mill. var. orientalis) storax against several bacteria.in this study, siğla (liquidambar orientalis mill.) storax (styrax) was investigated for antibacterial activity against aeromonas hydrophila, bacillus amyloliquefaciens, b. brevis, b. cereus, b. megaterium, b. subtilis, corynebacterium xerosis, enterobacter aerogenes, enterococcus faecalis, escherichia coli, e. coli o157:h7, klebsiella pneumoniae, listeria monocytogenes, micrococcus luteus, mycobacterium smegmatis, proteus vulgaris, pseudomonas aeruginosa, p. fluorescens, staphylococcus aureus a ...200516114094
development and evaluation of 16s rdna microarray for detecting bacterial pathogens in cerebrospinal fluid.the rapid identification of bacteria in cerebrospinal fluid (csf) is very important for patient management and antimicrobial therapies. we developed a 16s dna microarray-based method that targets 16s rdna and can directly detect bacteria from csf without cultivation. universal primers and specific probes were designed from the 16s rdna sequence data retrieved directly from the genbank database. the specificity of the assay is obtained through a combination of microarray hybridization and enzymat ...200516118409
bacteria isolated from blood, stool and urine of typhoid patients in a developing country.blood, stool and urine samples were collected from 100 patients diagnosed as having typhoid in 5 hospitals in akwa ibom state and analyzed for the presence of salmonella species and other bacteria. of the 100 blood samples screened, 55 (55%) were positive with the widal test and 39 (39%) were positive on blood culture. thirteen (14.1%) out of 92 urine samples were positive for bacterial growth, while 22 (26.8%) of the stool cultures were positive out of the 82 samples screened. those within the ...200516124436
a strategy for the control of catheter blockage by crystalline proteus mirabilis biofilm using the antibacterial agent triclosan.catheter blockage by crystalline proteus mirabilis biofilm is a common complication in patients undergoing long-term indwelling bladder catheterisation. previously we have shown that inflating the retention balloons of all-silicone catheters with triclosan solutions prevents the encrustation process. the aim of the present work was to examine whether this strategy is effective in latex-based catheters.200516126323
synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 1. synthesis and antimicrobial activity of (benzofuran-2-yl)(3-phenyl-3-methylcyclobutyl) ketoxime derivatives.the reaction of salicylaldehyde with 1-phenyl-1-methyl-3-(2-chloro-1-oxoethyl) cyclobutane (1) and potassium carbonate was used to prepare (benzofuran-2-yl)(3-methyl-3-phenylcyclobutyl) methanone (2) for the starting reagent purposes. (benzofuran-2-yl)(3-phenyl-3-methyl cyclobutyl) ketoxime (3) was synthesized from the reaction of the compound (2) with hidroxylamine. new derivatives of (benzofuran-2-yl)(3-phenyl-3-methyl cyclobutyl) ketoxime (3) such as, o-glycidylketoxime (4) and o-phenylacylke ...200516129517
synthesis of schiff bases of 2-amino-5-aryl-1,3,4-oxadiazoles and their evaluation for antimicrobial activities.twenty schiff bases of 2-amino-5-aryl-1,3,4-oxadiazoles have been synthesized with different aromatic aldehydes. the structures of the compounds were confirmed by nitrogen analysis, ir and 13c-nmr spectral data. the antibacterial properties of the compounds were investigated against proteus mirabilis (mtcc-425), pseudomonas aeruginosa (mtcc-424), bacillus subtilis (mtcc-619) and staphylococcus aureus (mtcc-96) using the broth dilution method. the most active compounds were 4c (64 microg/ml), 4f ...200515942874
characterisation of the rac/pak pathway in amoeba proteus.molecular mechanisms underlying the unique locomotion of the highly motile amoeba proteus still remain poorly understood. recently, we have shown that blocking the endogenous amoebal rac-like protein(s) leads to distinct and irreversible changes in the appearance of these large migrating cells as well as to a significant inhibition of their locomotion. to elucidate the mechanism of the rac pathway in amoeba proteus, we tested the effects of blocking the endogenous myosin i heavy chain kinase (mi ...200515948264
sesquin, a potent defensin-like antimicrobial peptide from ground beans with inhibitory activities toward tumor cells and hiv-1 reverse transcriptase.an antifungal peptide with a molecular mass around 7 kda and an n-terminal sequence highly homologous to defensin was isolated from ground beans (vigna sesquipedalis cv. 'ground bean'). the peptide was adsorbed on affi-gel blue gel and on mono s. it exerted an antifungal action on botrytis cinerea, fusarium oxysporum and mycosphaerella arachidicola; and an antibacterial action on escherichia coli b, proteus vulgaris, mycobacterium phlei and bacillus megaterium. the antimicrobial activity was inh ...200515949629
adaptation to extreme environments: macromolecular dynamics in complex systems.what we previously thought of as insurmountable physical and chemical barriers to life, we now see as yet another niche harbouring 'extremophiles'. extremophiles and their macromolecules had to develop molecular mechanisms of adaptation to extreme physico-chemical conditions. using neutron spectroscopy, we have demonstrated that molecular dynamics represents one of these molecular mechanisms of adaptation. to which extent do hyper-saline conditions and extreme temperatures influence molecular dy ...200515951115
plasmid-mediated, inducible ampc beta-lactamase (dha-1)-producing enterobacteriaceae at a korean hospital: wide dissemination in klebsiella pneumoniae and klebsiella oxytoca and emergence in proteus mirabilis.the aim of the study was to investigate the phenotypic and genetic characteristics of recently emerging cefoxitin-resistant and induction-positive isolates of escherichia coli, klebsiella species, and proteus mirabilis. strains of enterobacteriaceae were isolated at a korean tertiary care hospital between june and december 2002. induction was tested using cefoxitin and aztreonam disks, the bladha allele was detected by pcr, and pulsed-field gel electrophoresis (pfge) patterns were also analyzed. ...200515936167
structure of a lactic acid ether-containing and glycerol phosphate-containing o-polysaccharide from proteus mirabilis o40.an o-polysaccharide was isolated by mild acid hydrolysis from the lipopolysaccharide of proteus mirabilis o40 and studied by nmr spectroscopy, including 2d 1h, 1h cosy, tocsy, roesy, and 1h, 13c hmqc experiments, along with chemical methods. the polysaccharide was found to contain an ether of glcnac with lactic acid and glycerol phosphate in the main chain and to have the following structure: --> 3)-beta-d-glcpnac4(r-lac)-(1 --> 3)-alpha-d-galp-(1 --> 3)-d-gro-1-p-(o --> 3)-beta-d-glcpnac-(1 --> ...200515890320
recalcitrant scoliosis in proteus syndrome.proteus syndrome is a rare congenital condition with various clinical features such as hemihypertrophy, macrodactyly, subcutaneous masses, brain-like hyperplasia of the soles and/or palms, epidermal naevi and scoliosis with other mesodermal malformations. multifocal overgrowth can affect various tissues causing severe functional and cosmetic disability, but intellectual and language development are mostly normal. orthopaedic problems include macrodactyly, hindfoot deformity, limb length inequali ...200516035717
antimicrobial susceptibility patterns of contemporary pathogens from uncomplicated urinary tract infections isolated in a multicenter italian survey: possible impact on guidelines.during 2004 four italian laboratories assessed the prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in female out-patients. a total of 600 urine samples from individuals aged 18-65 were studied. the overall prevalence of escherichia coli was 85.3%. klebsiella pneumoniae, staphylococcus saprophyticus, proteus mirabilis, enterococcus faecalis and other rarer species were far less represented. determination of the antibiotic susceptibility pattern of th ...200516038517
antibacterial and antioxidant activities of ethanol extract from paullinia cupana mart.the antibacterial and antioxidant activity of the ethanol extract from paullinia cupana var. sorbilis mart. (sapindaceae) seeds, commonly called guarana, was assessed towards selected bacteria as well as in different antioxidant models. the extract, at a concentration between 16 and 128 microg/ml, showed a significant antibacterial effect expressed as minimum inhibitory concentration (mic) against both gram-negative and gram-positive bacteria. in particular, pseudomonas aeruginosa (mic=16 microg ...200516040216
tigecycline.new antimicrobial agents are urgently needed for clinical use due to the increasing prevalence and spread of multidrug-resistant bacteria that are commonly responsible for serious and life-threatening diseases. the need to develop new agents that effectively overcome existing mechanisms of resistance displayed by bacteria resistant to currently available drugs has become paramount. tigecycline, the first in a new class of antimicrobials, the glycylcyclines, is an analogue of minocycline with add ...200516040625
dentomaxillofacial imaging in proteus syndrome.proteus syndrome is a rare condition that involves atypical growth of the bones, skin and head and a variety of other symptoms. only a few authors have reported on the craniofacial manifestations so far. the authors present a case of a 7-year-old girl with proteus syndrome in which the facial skeleton showed unilateral overgrowth. the analysis of the radiological evaluation revealed a bialveolar prognathism, a skeletal class iii, a dolicocephalic growth pattern and a left convex face scoliosis. ...200515961602
spread of novel expanded-spectrum beta-lactamases in enterobacteriaceae in a university hospital in the paris area, france.in 2002, 28 non-duplicate enterobacterial isolates producing extended-spectrum beta-lactamases (esbls) were collected from infected patients at the bicêtre hospital in paris, france. escherichia coli was the predominant esbl-positive enterobacterial species, comprising ten (36%) of the isolates. ctx-m enzymes (ctx-m-3, ctx-m-10, ctx-m-14 and ctx-m-15) were produced by 11 (39%) of the isolates (six e. coli, two enterobacter cloacae, one enterobacter aerogenes, one proteus mirabilis and one citrob ...200515966981
first description of dha-1 ampcbeta-lactamase in proteus mirabilis.this report describes the first occurrence of the dha-1 ampcbeta-lactamase gene in proteus mirabilis. the organism was isolated from the vaginal flora of a pregnant woman in a french hospital. the dha-1 beta-lactamase gene was identified on the basis of phenotypic characteristics, pcr amplification and sequencing. antagonism between cefoxitin and the other cephalosporins suggested inducible production of the dha-1 enzyme.200515966982
in-vitro antibacterial, antifungal and cytotoxic properties of sulfonamide--derived schiff's bases and their metal complexes.a series of new antibacterial and antifungal schiff's bases derived from sulfonamides, as well as their transition metal complexes incorporating cobalt (ii), copper (ii), nickel (ii) and zinc (ii) were synthesized, characterized and screened for their in-vitro antibacterial activity against six gram-negative (escherichia coli, klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa, salmonella typhi and shigella dysentriae) and four gram-positive (bacillus cereus, corynebacterium diphth ...200515968823
[antibiotic resistance transformation in community-acquired urinary infections].to detect the prevalence of uropathogens in community-acquired urinary tract infection in our environment, and the degree of sensitivity to antibiotics used as empirical treatment.200515970133
noninvasive biophotonic imaging for monitoring of catheter-associated urinary tract infections and therapy in mice.urinary tract infections (utis) are among the most common bacterial infections acquired by humans, particularly in catheterized patients. a major problem with catheterization is the formation of bacterial biofilms on catheter material and the risk of developing persistent utis that are difficult to monitor and eradicate. to better understand the course of utis and allow more accurate studies of in vivo antibiotic efficacy, we developed a catheter-based biofilm infection model with mice, using bi ...200515972473
Displaying items 13501 - 13600 of 15180