Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| modeling the flux of metabolites in the juvenile hormone biosynthesis pathway using generalized additive models and ordinary differential equations. | juvenile hormone (jh) regulates development and reproductive maturation in insects. the corpora allata (ca) from female adult mosquitoes synthesize fluctuating levels of jh, which have been linked to the ovarian development and are influenced by nutritional signals. the rate of jh biosynthesis is controlled by the rate of flux of isoprenoids in the pathway, which is the outcome of a complex interplay of changes in precursor pools and enzyme levels. a comprehensive study of the changes in enzymat ... | 2017 | 28158248 |
| [zika virus infection in pregnancy]. | the zika virus is a flavivirus spread by mosquitoes. its primary vectors are the aedes aegypti and the aedes albopictus. before 2007 it sporadically caused benign morbidity. since 2015, it started spreading "explosively" in america, especially in brazil. in august 2016 they reported cases from new york and poland, too. most of the infections don't produce any symptoms, but can cause grave complications. the most important lesion is microcephalia that forms in fetuses. microcephalia's most seriou ... | 2017 | 28393598 |
| new records of aedes aegypti in southern oklahoma, 2016. | aedes aegypti is an important subtropical vector species and is predicted to have a limited year-round distribution in the southern united states. collection of the species has not been officially verified in oklahoma since 1940. adult mosquitoes were collected in 42 sites across 7 different cities in oklahoma using 3 different mosquito traps between may and september 2016. between july and september 2016, 88 ae. aegypti adults were collected at 18 different sites in 4 different cities across so ... | 2017 | 28388329 |
| a large scale biorational approach using bacillus thuringiensis israeliensis (strain am65-52) for managing aedes aegypti populations to prevent dengue, chikungunya and zika transmission. | aedes aegypti is a container-inhabiting mosquito and a vector of dengue, chikungunya, and zika viruses. in 2009 several cases of autochthonous dengue transmission were reported in key west, florida, usa prompting a comprehensive response to control a. aegypti. in key west, larvae of this mosquito develop in containers around human habitations which can be numerous and labor intensive to find and treat. aerial applications of larvicide covering large areas in a short time can be an efficient and ... | 2017 | 28199323 |
| levels of insecticide resistance to deltamethrin, malathion, and temephos, and associated mechanisms in aedes aegypti mosquitoes from the guadeloupe and saint martin islands (french west indies). | in the guadeloupe and saint martin islands, aedes aegypti mosquitoes are the only recognized vectors of dengue, chikungunya, and zika viruses. for around 40 years, malathion was used as a mosquito adulticide and temephos as a larvicide. since the european union banned the use of these two insecticide molecules in the first decade of the 21st century, deltamethrin and bacillus thuringiensis var. israelensis are the remaining adulticide and larvicide, respectively, used in guadeloupe. in order to ... | 2017 | 28187780 |
| response of three cyprinid fish species to the scavenger deterrent factor produced by the mutualistic bacteria associated with entomopathogenic nematodes. | the symbiotic bacteria, photorhabdus and xenorhabdus associated with entomopathogenic nematodes (epns) in the genera heterorhabditis and steinernema, respectively, produce a compound(s) called the scavenging deterrent factor (sdf). sdf deters a number of terrestrial insect scavengers and predators and one bird species from feeding on host insects killed by the nematode-bacterium complex but has not been tested against aquatic vertebrates. moreover, the heterorhabditis-photorhabdus association is ... | 2017 | 27908637 |
| [control of aedes aegypti breeding sites with the program recicla por tu bienestar in merida, mexico]. | to determine the importance of ae. aegypti breeding-sites in merida;to evaluate the impact of recicla por tu bienestar (rxb, a recycling program) on the reduction of breeding sites and the perception of participants. | 2017 | 26302122 |
| aedes aegypti (diptera: culicidae) in a tree hole in brazil. | 2017 | 27384845 | |
| serious disease outbreaks caused by viruses transmitted by aedes aegypti in brazil. | 2017 | 27384820 | |
| impact of micropollutants on the life-history traits of the mosquito aedes aegypti: on the relevance of transgenerational studies. | hazard assessment of chemical contaminants often relies on short term or partial life-cycle ecotoxicological tests, while the impact of low dose throughout the entire life cycle of species across multiple generations has been neglected. this study aimed at identifying the individual and population-level consequences of chronic water contamination by environmental concentrations of three organic micropollutants, ibuprofen, bisphenol a and benzo[a]pyrene, on aedes aegypti mosquito populations in e ... | 2017 | 27667679 |
| sexual chemoecology of mosquitoes (diptera, culicidae): current knowledge and implications for vector control programs. | mosquitoes (diptera: culicidae) act as vectors of medical and veterinary importance, due to their ability to transmit many pathogens and parasites. renewed interest has been recently devoted to the potential of sterile insect technique (sit) for mosquito suppression. however, the success of the sit is mostly dependent on the ability of sterile males to compete for mates with the wild ones in the field. nevertheless, little is known on the sexual chemical ecology of mosquitoes, with special refer ... | 2017 | 27692501 |
| changes in infestation sites of female aedes aegypti in northeast brazil. | we report the behavioral changes in use of oviposition sites in aedes aegypti in fortaleza, brazil. | 2017 | 27598639 |
| cost of intensive routine control and incremental cost of insecticide-treated curtain deployment in a setting with low aedes aegypti infestation. | information regarding the cost of implementing insecticide-treated curtains (itcs) is scarce. therefore, we evaluated the itc implementation cost, in addition to the costs of intensive conventional routine activities of the aedes control program in the city of guantanamo, cuba. | 2017 | 27598627 |
| molecular docking and simulation studies of gustatory receptor of aedes aegypti: a potent drug target to distract host-seeking behaviour in mosquitoes. | it is well reported that exhaled co 2 and skin odour from human being assist female mosquitoes to locate human host. basically, the receptors for this activity are expressed in cpa neurons. in both aedes aegypti and anopheles gambiae, this co 2-sensitive olfactory neuron detects myriad number of chemicals present in human skin. therefore, manipulation of gustatory receptors housing these neurons may serve as important targets for behavioural intervention. the study was aimed towards virtual scre ... | 2017 | 27353589 |
| impact of container material on the development of aedes aegypti larvae at different temperatures. | aedes aegypti, the primary vector of dengue generally breeds in intradomestic and peridomestic containers made up of different materials, i.e. plastic, iron, rubber, earthen material etc. the material of container is likely to affect the temperature of water in container with variation in environmental temperature. the present study was aimed to determine the effect of different container materials on larval development of ae. aegypti at different temperatures. | 2017 | 27353584 |
| spatial distribution and insecticide susceptibility status of aedes aegypti and aedes albopictus in dengue affected urban areas of rawalpindi, pakistan. | dengue is one of the most common arthropod-borne viral diseases which is transmitted mainly by two vector species, aedes aegypti (linnaeus 1762) and ae. albopictus (skuse, 1894) worldwide. as there is no effective medicine and vaccine available, vector control remains the most effective measure to prevent its transmission and outbreak. the aim of the study was to confirm the co-occurrence of aedes aegypti and ae. albopictus populations in the different localities of rawalpindi, pakistan and exam ... | 2017 | 27353583 |
| spatial analysis of wing geometry in dengue vector mosquito, aedes aegypti (l.) (diptera: culicidae), populations in metropolitan manila, philippines. | aedes aegypti (l.) is an efficient vector for arboviral diseases such as dengue. the wings of ae. aegypti has been extensively studied in order to investigate population heterogeneity and structure by utilizing a landmark based geometric morphometrics (gms) approach. the aim of this study was to examine and assess the wing geometry of ae. aegypti in metropolitan manila. | 2017 | 27353582 |
| toxicity of squamocin on aedes aegypti larvae, its predators and human cells. | the mosquito aedes aegypti transmits a virus that causes diverse human diseases, and control of the vector is an important strategy to avoid disease propagation. plants in the family annonaceae are recognised as sources of molecules with uses in the medical and agriculture fields. molecules of secondary metabolites of annonaceae plants exhibit insecticidal potential against insect pests and vectors, especially acetogenins, showing high toxicity at low doses, which has encouraged research into pr ... | 2017 | 27366879 |
| synthesis and insecticidal activity of acridone derivatives to aedes aegypti and culex quinquefasciatus larvae and non-target aquatic species. | a serious mosquito borne yellow fever is one of the grave diseases which affect the major population. since there is no specific treatment for yellow fever, there is a necessity to develop an effective agent. the series of acridinone analogues 3 to 5 were synthesized with help of non-conventional microwave heating and confirmed by respective spectral characterization. 5c and 3b showed highest activity to kill 90% of larvae against a. aegypti and c. quinquefasciatus, respectively. also the active ... | 2017 | 28059104 |
| discovery of flavivirus-derived endogenous viral elements in anopheles mosquito genomes supports the existence of anopheles-associated insect-specific flaviviruses. | the flavivirus genus encompasses several arboviruses of public health significance such as dengue, yellow fever, and zika viruses. it also includes insect-specific flaviviruses (isfs) that are only capable of infecting insect hosts. the vast majority of mosquito-infecting flaviviruses have been associated with mosquito species of the aedes and culex genera in the culicinae subfamily, which also includes most arbovirus vectors. mosquitoes of the anophelinae subfamily are not considered significan ... | 2017 | 28078104 |
| functional analysis of the abcs of eye color in helicoverpa armigera with crispr/cas9-induced mutations. | many insect pigments are localized in subcellular pigment granules, and transport of pigment precursors from the cytoplasm is accomplished by abc proteins. drosophila melanogaster has three half-transporter genes (white, scarlet, and brown, all affecting eye pigments) and bombyx mori has a fourth (ok). the white, brown, scarlet and ok proteins each have one transmembrane and one cytoplasmic domain and they heterodimerize to form functional transporters with different substrate specificities. we ... | 2017 | 28053351 |
| incidence of dengue and chikungunya viruses in mosquitoes and human patients in border provinces of vietnam. | dengue virus remains a major threat in vietnam, while chikungunya virus is expected to become one. surveillance was conducted from 2012 to 2014 in vietnam to assess the presence of dengue and chikungunya viruses in patients hospitalized with acute fever in five vietnam provinces neighboring lao pdr and cambodia. surveillance was extended to mosquitoes present in the vicinity of the patients' households. | 2017 | 29121985 |
| the impact of temperature and wolbachia infection on vector competence of potential dengue vectors aedes aegypti and aedes albopictus in the transmission of dengue virus serotype 1 in southern taiwan. | we evaluated the impact of temperature and wolbachia infection on vector competence of the local aedes aegypti and ae. albopictus populations of southern taiwan in the laboratory. | 2017 | 29116011 |
| assessment of achyranthes aspera induced toxicity and molecular analysis of rapd-pcr profiles of larval genomic dna of aedes aegypti l. (diptera: culicidae). | current studies investigated the anti-mosquito potential of achyranthes aspera against the dengue vector, aedes aegypti. the stems and leaves of a. aspera were extracted in hexane and evaluated for their toxicity against early fourth instars of a. aegypti. the larvicidal efficacy of the extract was validated as per who protocol. the mortality counts were made after 24 h and lc values were calculated at different levels. the adverse impact of extracts was also explored on the larval genomic dna. ... | 2017 | 29114143 |
| a blood meal enhances innexin mrna expression in the midgut, malpighian tubules, and ovaries of the yellow fever mosquito aedes aegypti. | mosquitoes are vectors of pathogens that cause diseases of medical and veterinary importance. female mosquitoes transmit these pathogens while taking a blood meal, which most species require to produce eggs. the period after a blood meal is a time of extreme physiological change that requires rapid coordination of specific tissues. gap junctions (gj) are intercellular channels that aid in the coordination of cells within tissues via the direct transfer of certain small molecules and ions between ... | 2017 | 29113099 |
| aedes aegypti molecular responses to zika virus: modulation of infection by the toll and jak/stat immune pathways and virus host factors. | zika (zikv) and dengue virus (denv) are transmitted to humans by aedes mosquitoes. however, the molecular interactions between the vector and zikv remain largely unexplored. in this work, we further investigated the tropism of zikv in two different aedes aegypti strains and show that the virus infection kinetics, tissue migration, and susceptibility to infection differ between mosquito strains. we also compare the vector transcriptome changes upon zikv or denv infection demonstrating that 40% of ... | 2017 | 29109710 |
| surveillance of intensity level and geographical spreading of dengue outbreak among males and females in punjab, pakistan: a case study of 2011. | dengue fever is viral disease which spreads due to the bite of the aedes aegypti mosquito. in recent years, it has affected around 40% population of the world. its endemic flow has led to a large disease burden, in terms of human and financial resources. | 2017 | 29103928 |
| designing ecofriendly bionanocomposite assembly with improved antimicrobial and potent on-site zika virus vector larvicidal activities with its mode of action. | dialyzed natural polymer, fibroin, from bombyx mori was used to synthesize biocompatible silver and gold nanoparticles in-situ in dispersion form. the films of pure fibroin (pf), fibroin-silver nanocomposite (fsnc) and fibroin-gold nanocomposite (fgnc) were fabricated by drop casting method. the characterization of the resultant dispersion and films was performed by visual color change, uv-vis spectroscopy and atomic force microscopy. the dispersions of pf, fsnc and fgnc were tested for antibact ... | 2017 | 29138496 |
| germline cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, aedes aegypti. | the development of crispr/cas9 technologies has dramatically increased the accessibility and efficiency of genome editing in many organisms. in general, in vivo germline expression of cas9 results in substantially higher activity than embryonic injection. however, no transgenic lines expressing cas9 have been developed for the major mosquito disease vector aedes aegypti here, we describe the generation of multiple stable, transgenic ae. aegypti strains expressing cas9 in the germline, resulting ... | 2017 | 29138316 |
| the diversity, structure, and function of heritable adaptive immunity sequences in the aedes aegypti genome. | the aedes aegypti mosquito transmits arboviruses, including dengue, chikungunya, and zika virus. understanding the mechanisms underlying mosquito immunity could provide new tools to control arbovirus spread. insects exploit two different rnai pathways to combat viral and transposon infection: short interfering rnas (sirnas) and piwi-interacting rnas (pirnas) [1, 2]. endogenous viral elements (eves) are sequences from non-retroviral viruses that are inserted into the mosquito genome and can act a ... | 2017 | 29129531 |
| biosurfactants produced by scheffersomyces stipitis cultured in sugarcane bagasse hydrolysate as new green larvicides for the control of aedes aegypti, a vector of neglected tropical diseases. | biosurfactants are microbial metabolites with possible applications in various industrial sectors that are considered ecofriendly molecules. in recent years, some studies identified these compounds as alternatives for the elimination of vectors of tropical diseases, such as aedes aegypti. the major bottlenecks of biosurfactant industrial production have been the use of conventional raw materials that increase production costs as well as opportunistic or pathogenic bacteria, which restrict the ap ... | 2017 | 29125845 |
| infection of a french population of aedes albopictus and of aedes aegypti (paea strain) with zika virus reveals low transmission rates to these vectors' saliva. | disease caused by the zika virus (zikv) is a public health emergency of international concern. recent epidemics have emerged in different regions of the world and attest to the ability of the virus to spread wherever its vector, aedes species mosquitoes, can be found. we have compared the transmission of zikv by ae. aegypti (paea strain originating from tahiti) and by a french population of ae. albopictus to better assess their competence and the potential risk of the emergence of zikv in europe ... | 2017 | 29125545 |
| evaluation of sticky traps for adult aedes mosquitoes in malaysia: a potential monitoring and surveillance tool for the efficacy of control strategies. | the present study compared the performance of sticky traps in order to identify the most effective and practical trap for capturing aedes aegypti and aedes albopictus mosquitoes. three phases were conducted in the study, with phase 1 evaluating the five prototypes (models a, b, c, d, and e) of sticky trap release-and-recapture using two groups of mosquito release numbers (five and 50) that were released in each replicate. similarly, phase 2 compared the performance between model e and the classi ... | 2017 | 29125255 |
| the distribution of mosquitoes across an altitudinal gradient in the galapagos islands. | an avian malaria parasite (genus plasmodium) has been detected consistently in the galapagos penguin (spheniscus mendiculus) and less frequently in some passerines. we sampled three resident mosquito species (aedes taeniorhynchus, culex quinquefasciatus, and aedes aegypti) using cdc light and gravid traps on three islands in 2012, 2013, and 2014. we sampled along altitudinal gradients to ask whether there are mosquito-free refugia at higher elevations as there are in hawaii. we captured both ae. ... | 2017 | 29125252 |
| ecological characterization of aedes aegypti larval habitats (diptera: culicidae) in artificial water containers in girardot, colombia. | the establishment of habitats for immature ae. aegypti is regulated by biotic and abiotic factors and interactions between these factors. this study aimed to determine the effects of physico-chemical variables and planktonic algae on immature ae. aegypti habitats in 101 water tanks (50 of them containing ae. aegypti pupae and/or larvae) in girardot, colombia. physical data were collected from the water tanks (volume, capacity, material, detritus, and location), along with the physico-chemical va ... | 2017 | 29125250 |
| first record of aedes aegypti and aedes albopictus in thirteen panhandle region counties of texas, u.s.a. | 2017 | 29125249 | |
| emergent acoustic order in arrays of mosquitoes. | the yellow fever mosquito aedes aegypti forms aerial swarms that serve as mating aggregations [1]. despite lacking the remarkable collective order of other animal ensembles, such as fish and birds [2], the kinematic properties of these swarms bear the hallmarks of local interaction and global cohesion [3,4]. however, the mechanisms responsible for collective behaviour in mosquitoes are not well understood. mosquitoes use their antennae as hearing organs to locate and interact with one another vi ... | 2017 | 29161555 |
| dengue virus detection in aedes aegypti larvae and pupae collected in rural areas of anapoima, cundinamarca, colombia. | there is a high incidence and prevalence of dengue in the department of cundinamarca, and recently aedes aegypti, the main vector of dengue virus (denv), was detected in some of its rural areas. | 2017 | 29161491 |
| effect of the type and number of washes in the efficacy of long lasting insecticidal nets for aedes aegypti control in girardot, colombia. | the use of long lasting insecticidal materials has shown promising results in the control of aedes aegypti. | 2017 | 29161489 |
| virological surveillance of aedes (stegomyia) aegypti and aedes (stegomyia) albopictus as support for decision making for dengue control in medellín. | dengue represents an important public health problem in colombia. no treatment is available and the vaccine has not been approved in all countries, hence, actions should be strengthened to mitigate its impact through the control of aedes aegypti, the vector mosquito. in colombia, surveillance is done using entomological indexes and case notification, which is usually informed late, leading to untimely interventions. viral detection in urban mosquitoes using molecular techniques provides more acc ... | 2017 | 29161487 |
| aedes albopictus (skuse, 1894) infected with the american-asian genotype of dengue type 2 virus in medellín suggests its possible role as vector of dengue fever in colombia. | aedes aegypti and ae. albopictus are recognized vectors of dengue, yellow fever, chikungunya and zika arboviruses in several countries worldwide. in colombia, ae. albopictus geographical distribution has increased to include highly populated cities such as cali and medellín. although this species has been frequently found in urban and semi-urban zones in the country, its role as vector of the dengue fever is poorly known. | 2017 | 29161485 |
| [laboratory susceptibility tests of aedes aegypti and culex quinquefasciatus larvae to the entomopathogenic nematode heterorhabditis bacteriophora]. | aedes aegypti is the vector of dengue, yellow fever, zika and chikungunya viruses, and culex quinquefasciatus is the vector of st. louis and west nile encephalitis viruses. | 2017 | 29161479 |
| [spatial distribution of potential and positive aedes aegypti breeding sites]. | the spatial distribution of aedes aegypti is heterogeneous, and the interaction between positive and potential breeding sites located both inside and outside homes is one of the most difficult aspects to characterize in vector control programs. | 2017 | 29161478 |
| [spatial distribution of aedes aegypti (diptera: culicidae) in the rural area of two municipalities of cundinamarca, colombia]. | it is difficult to adapt or create new strategies for dengue control in rural areas due to the dispersion of homes and the lack of knowledge about the presence and behavior of the vector in these areas. spatial data analysis could help understand time and space dynamics related to the transmission of vector-borne diseases in rural areas and, thus, contribute to the prevention and control of dengue. | 2017 | 29161476 |
| alternative control of aedes aegypti resistant to pyrethroids: lethal and sublethal effects of monoterpenes bioinsecticides. | the mosquito aedes aegypti is intensely controlled because it is vector of viruses that cause innumerous diseases, especially in tropical regions. due to the indiscriminate use of insecticides, populations from different regions have been resistant to pyrethroids. here, we analyzed the lethal and sublethal effects of essential oil of aristolochia trilobata and its major compounds on a. aegypti from susceptible and pyrethroid resistant populations. | 2017 | 29160036 |
| upregulation of aedes aegypti vago1 by wolbachia and its effect on dengue virus replication. | dengue infection along with its related disease conditions poses a significant threat to human health. the pathogen responsible for this infection is dengue virus (denv) which is primarily transmitted to humans through the bites of aedes aegypti mosquitoes. unavailability of a potent vaccine has recently sparked renewed research endeavours aimed at vector control. to date, wolbachia as an endosymbiotic bacterium has shown promise as a novel biocontrol agent to restrict denv replication in the ve ... | 2017 | 29157676 |
| a call to introduce structured zika surveillance in india. | india has the climatic conditions conducive to year-round transmission of zika virus, and a structured disease surveillance program should be implemented to prevent an outbreak. such a program should (i) start screening before an outbreak arises; (ii) collect baseline data to assess future disease risk and monitor potential birth defects; and (iii) provide new insights into the ecology of the disease and inform public health policy following the one health concept. | 2017 | 29153262 |
| effective population sizes of a major vector of human diseases, aedes aegypti. | the effective population size (ne ) is a fundamental parameter in population genetics that determines the relative strength of selection and random genetic drift, the effect of migration, levels of inbreeding, and linkage disequilibrium. in many cases where it has been estimated in animals, ne is on the order of 10%-20% of the census size. in this study, we use 12 microsatellite markers and 14,888 single nucleotide polymorphisms (snps) to empirically estimate ne in aedes aegypti, the major vecto ... | 2017 | 29151858 |
| vectors, hosts, and control measures for zika virus in the americas. | we examine zika virus (zikv) from an ecological perspective and with a focus on the americas. we assess (1) the role of wildlife in zikv disease ecology, (2) how mosquito behavior and biology influence disease dynamics, and (3) how nontarget species and ecosystems may be impacted by vector control programs. our review suggests that free-ranging, non-human primates may be involved in zikv transmission in the old world; however, other wildlife species likely play a limited role in maintaining or t ... | 2017 | 29150828 |
| the introduction of dengue follows transportation infrastructure changes in the state of acre, brazil: a network-based analysis. | human mobility, presence and passive transportation of aedes aegypti mosquito, and environmental characteristics are a group of factors which contribute to the success of dengue spread and establishment. to understand this process, we assess data from dengue national and municipal basins regarding population and demographics, transportation network, human mobility, and ae. aegypti monitoring for the brazilian state of acre since the first recorded dengue case in the year 2000 to the year 2015. d ... | 2017 | 29149175 |
| baccharis reticularia dc. and limonene nanoemulsions: promising larvicidal agents for aedes aegypti (diptera: culicidae) control. | baccharis reticularia dc. is a plant species from the asteraceae family that is endemic to brazil. despite the great importance of baccharis genus, no study has been carried out regarding either the phytochemical composition of b. reticularia or the evaluation of its larvicidal potential. considering the intrinsic immiscibility of essential oils, this study shows larvicidal nanoemulsions containing the b. reticularia phytochemically characterized essential oil and its main constituent against ae ... | 2017 | 29149027 |
| [dengue fever : symptoms, epidemiology, entomology, pathogen diagnosis and prevention]. | dengue infections are among the most frequent causes of febrile disease in tropical climates. infections are caused by a flavivirus transmitted by the aedes mosquito. aedes aegypti mosquitos are the main transmitters of dengue viruses. since these insects are both diurnal and container breeders, particular prevention and control measures are required. symptom severity varies and can range from a mild, flu-like clinical picture to severe hemorrhage and shock. the most common symptoms experienced ... | 2017 | 29147722 |
| development and physiological effects of an artificial diet for wolbachia-infected aedes aegypti. | the endosymbiotic bacterium wolbachia spreads rapidly through populations of aedes aegypti mosquitoes, and strongly inhibits infection with key human pathogens including the dengue and zika viruses. mosquito control programs aimed at limiting transmission of these viruses are ongoing in multiple countries, yet there is a dearth of mass rearing infrastructure specific to wolbachia-infected mosquitoes. one example is the lack of a blood meal substitute, which accounts for the wolbachia-specific ph ... | 2017 | 29146940 |
| behavioral, climatic, and environmental risk factors for zika and chikungunya virus infections in rio de janeiro, brazil, 2015-16. | the burden of arboviruses in the americas is high and may result in long-term sequelae with infants disabled by zika virus infection (zikv) and arthritis caused by infection with chikungunya virus (chikv). we aimed to identify environmental drivers of arbovirus epidemics to predict where the next epidemics will occur and prioritize municipalities for vector control and eventual vaccination. we screened sera and urine samples (n = 10,459) from residents of 48 municipalities in the state of rio de ... | 2017 | 29145452 |
| zika virus: an updated review of competent or naturally infected mosquitoes. | zika virus (zikv) is an arthropod-borne virus (arbovirus) that recently caused outbreaks in the americas. over the past 60 years, this virus has been observed circulating among african, asian, and pacific island populations, but little attention has been paid by the scientific community until the discovery that large-scale urban zikv outbreaks were associated with neurological complications such as microcephaly and several other neurological malformations in fetuses and newborns. this paper is a ... | 2017 | 29145400 |
| shifting the paradigm in dirofilaria immitis prevention: blocking transmission from mosquitoes to dogs using repellents/insecticides and macrocyclic lactone prevention as part of a multimodal approach. | this study assessed the influence of a topical ectoparasiticide (dinotefuran-permethrin-pyriproxyfen, dpp, vectra® 3d, ceva animal health) combined with a macrocyclic lactone (milbemycin oxime, mbo, interceptor®, virbac) on transmission of heartworm l3 from mosquitoes to dogs and subsequent development of worms in treated dogs exposed to infected mosquitoes. | 2017 | 29143678 |
| blocking the transmission of heartworm (dirofilaria immitis) to mosquitoes (aedes aegypti) by weekly exposure for one month to microfilaremic dogs treated once topically with dinotefuran-permethrin-pyriproxyfen. | this study assessed the influence of a topical ectoparasiticide (dinotefuran-permethrin-pyriproxyfen, dpp, vectra®3d, ceva animal health) on the acquisition of heartworm microfilariae by mosquitoes exposed to microfilaremic dogs weekly for 1 month. | 2017 | 29143651 |
| corrigendum: rna-seq comparison of larval and adult malpighian tubules of the yellow fever mosquito aedes aegypti reveals life stage-specific changes in renal function. | [this corrects the article on p. 283 in vol. 8, pmid: 28536536.]. | 2017 | 29142533 |
| analytical report of the 2016 dengue outbreak in córdoba city, argentina. | after elimination of the aedes aegypti vector in south america in the 1960s, dengue outbreaks started to reoccur during the 1990s; strongly in argentina since 1998. in 2016, córdoba city had the largest dengue outbreak in its history. in this article we report this outbreak including spatio-temporal analysis of cases and vectors in the city. a total of 653 dengue cases were recorded by the laboratory-based dengue surveillance system and georeferenced by their residential addresses. case maps wer ... | 2017 | 29239555 |
| assessing natural infection with zika virus in the southern house mosquito, culex quinquefasciatus, during 2016 in puerto rico. | the epidemic of zika in the western hemisphere has led to intense investigations of all species important in the transmission of zika virus (zikv), including putative mosquito vectors. although evidence points to stegomyia (= aedes) (diptera: culicidae) mosquitoes as the primary vectors in nature among humans, there remains the possibility that other common mosquito species may be implicated in the rapid spread of the virus. herein, field-caught culex quinquefasciatus (diptera: culicidae) collec ... | 2017 | 29239003 |
| aedes aegypti breeding site in an underground rainwater reservoir: a warning. | we describe the discovery of aedes aegypti underground breeding site in the pinheiros neighborhood of são paulo, sp, during an entomological survey program performed in 2016. even with intense surveillance and vector control, large numbers of mosquitoes were present in this area. a detailed investigation allowed for the detection of ae. aegypti in an underground reservoir used for rainwater storage. after the implementation of protection screens in the accesses, the presence of the vector was no ... | 2017 | 29236877 |
| detection of zika virus in aedes mosquitoes from mexico. | we report on the results of an entomovirological surveillance system of aedes populations performed by the ministry of health of the central state of san luis potosí, mexico. | 2017 | 29232453 |
| efficacy of 13 commercial household aerosol insecticides against aedes aegypti (diptera: culicidae) from morelos, mexico. | in mexico, aedes aegypti (l.) (diptera: culicidae) is the primary vector of dengue, zika, and chikungunya viruses. control programs include community participation using personal protection such as household aerosol insecticides. in both, urban or rural areas, the use of aerosol insecticides is a common practice to avoiding mosquito biting. thus, information on the efficacy of commercial products must be available. this study reports the efficacy of 13 household aerosol insecticides against ae. ... | 2017 | 29228197 |
| the first detected airline introductions of yellow fever mosquitoes (aedes aegypti) to europe, at schiphol international airport, the netherlands. | air-borne introduction of exotic mosquitoes to schiphol airport in the netherlands has been considered plausible based upon findings of mosquitoes in aircraft cabins during 2008, 2010 and 2011. beginning in 2013, surveillance efforts at schiphol had focused on promptly detecting accidental introductions at the airport facilities in order to quickly react and avoid temporary proliferation or establishment of mosquito populations, identify the origin of the introductions, and avoid potential trans ... | 2017 | 29221490 |
| full-length genome sequence of a chikungunya virus isolate from the 2017 autochthonous outbreak, lazio region, italy. | we report here the genome sequence of a human chikungunya virus isolate from the ongoing autochthonous outbreak in central italy. the sequence (east-central-south african lineage, indian ocean sublineage), which is similar to recent sequences from pakistan and india, shows e1 and e2 signatures of strains whose main mosquito vector is aedes aegypti, although aedes albopictus is the vector in italy. | 2017 | 29217791 |
| the gastric caecum of larval aedes aegypti: stimulation of epithelial ion transport by 5-hydroxytryptamine and camp. | we report measurements of ion transport across the gastric caecum of larvae of aedes aegypti, a vector of yellow fever that inhabits a variety of aquatic habitats ranging from freshwater to brackish water. we provide the first measurements of the effect of 5-hydroxytryptamine (5-ht) on transepithelial potential (tep), luminal ion concentrations and electrochemical potentials, as well as basolateral membrane potential and h+, na+ and k+ fluxes. tep, basolateral membrane potential, and h+, k+, and ... | 2017 | 29217627 |
| the immune strategies of mosquito aedes aegypti against microbial infection. | yellow fever mosquito aedes aegypti transmits many devastating arthropod-borne viruses (arboviruses), such as dengue virus, yellow fever virus, chikungunya virus, and zika virus, which cause great concern to human health. mosquito control is an effective method to block the spread of infectious diseases. ae. aegypti uses its innate immune system to fight against arboviruses, parasites, and fungi. in this review, we briefly summarize the recent findings in the immune response of ae. aegypti again ... | 2017 | 29217264 |
| differences in prevalence of symptomatic zika virus infection by age and sex-puerto rico, 2016. | during the zika virus (zikv) outbreak in puerto rico in 2016, non-pregnant women aged 20-39 years were disproportionately identified with zikv disease. we used household-based cluster investigations to determine if this disparity was associated with age- or sex-dependent differences in the rate of zikv infection or reporting symptoms. | 2017 | 29216376 |
| novel wolbachia-transinfected aedes aegypti mosquitoes possess diverse fitness and vector competence phenotypes. | wolbachia pipientis from drosophila melanogaster (wmel) is an endosymbiotic bacterium that restricts transmission of human pathogenic flaviviruses and alphaviruses, including dengue, zika, and chikungunya viruses, when introduced into the mosquito vector aedes aegypti. to date, wmel-infected ae. aegypti have been released in field trials in 5 countries to evaluate the effectiveness of this strategy for disease control. despite the success in establishing wmel-infected mosquitoes in wild populati ... | 2017 | 29216317 |
| dengue serotype-specific immune response in aedes aegypti and aedes albopictus. | dengue viruses (denv) are considered one of the most important emerging pathogens and dengue disease is a global health threat. the geographic expansion of dengue viruses has led to co-circulation of all four dengue serotypes making it imperative that new denv control strategies be devised. | 2017 | 29211244 |
| an aedes aegypti-associated fungus increases susceptibility to dengue virus by modulating gut trypsin activity. | transmission of dengue virus (denv) requires successful completion of the infection cycle in the aedes aegypti vector, which is initiated in the midgut tissue after ingestion of an infectious blood meal. while certain ae. aegypti midgut-associated bacteria influence virus infection, little is known about the midgut-associated fungi (mycobiota), and how its members might influence susceptibility to denv infection. we show that a talaromyces (tsp_pr) fungus, isolated from field-caught ae. aegypti, ... | 2017 | 29205153 |
| alternative patterns of sex chromosome differentiation in aedes aegypti (l). | some populations of west african aedes aegypti, the dengue and zika vector, are reproductively incompatible; our earlier study showed that divergence and rearrangements of genes on chromosome 1, which bears the sex locus (m), may be involved. we also previously described a proposed cryptic subspecies senaae (pk10, senegal) that had many more high inter-sex fst genes on chromosome 1 than did ae.aegypti aegypti (aaa, pai lom, thailand). the current work more thoroughly explores the significance of ... | 2017 | 29202694 |
| global transcriptome analysis of aedes aegypti mosquitoes in response to zika virus infection. | zika virus (zikv) of the flaviviridae family is a recently emerged mosquito-borne virus that has been implicated in the surge of the number of microcephaly instances in south america. the recent rapid spread of the virus led to its declaration as a global health emergency by the world health organization. the virus is transmitted mainly by the mosquito aedes aegypti, which is also the vector of dengue virus; however, little is known about the interactions of the virus with the mosquito vector. i ... | 2017 | 29202041 |
| global risk mapping for major diseases transmitted by aedes aegypti and aedes albopictus. | the objective of this study was to map the global risk of the major arboviral diseases transmitted by aedes aegypti and aedes albopictus by identifying areas where the diseases are reported, either through active transmission or travel-related outbreaks, as well as areas where the diseases are not currently reported but are nonetheless suitable for the vector. | 2017 | 29196275 |
| larvicidal and residual activity of imidazolium salts against aedes aegypti (diptera: culicidae). | aedes aegypti is an important species of mosquito, which can transmit several arboviruses such as dengue fever, yellow fever, chikungunya, and zika. as these mosquitoes are becoming resistant to most chemical insecticides used in the world, studies with new larvicides should be prioritized. based on the known biological profile of imidazolium salts (is), the objective of this study was to evaluate the potential of six is as larvicides against ae. aegypti, which was tested against ae. aegypti lar ... | 2017 | 29193680 |
| first insights on insecticidal activity upon aedes aegypti and partial biochemical characterization of a novel low molecular mass chymotrypsin-trypsin inhibitor purified from lonchocarpus sericeus seeds. | arboviroses such as dengue, zika and chikungunya represent a serious issue in public health due to the absence of approved vaccine or specific antiviral drugs. one way to prevent these diseases is by combating the vector mosquito, aedes aegypti (diptera), which has serine proteases in the midgut. protease inhibitors are molecules that can block enzyme activity impairing digestion and nutrition that can lead to death. thus, we purified and characterized a novel chymotrypsin- trypsin inhibitor fro ... | 2017 | 29193604 |
| aedes aegypti microrna mir-2b regulates ubiquitin-related modifier to control chikungunya virus replication. | arboviruses that replicate in mosquitoes activate innate immune response within mosquitoes. regulatory non-coding micrornas (mirna) are known to be modulated in mosquitoes during chikungunya infection. however, information about targets of these mirnas is scant. the present study was aimed to identify and analyze targets of mirnas that are regulated during chikungunya virus (chikv) replication in aedes aegypti cells and in the mosquito. employing next-generation sequencing technologies, we ident ... | 2017 | 29247247 |
| zika virus can be venereally transmitted between aedes aegypti mosquitoes. | alternative transmission routes have been described for zika virus (zikv). here, we assessed for the first time the venereal transmission of zikv between aedes aegypti under laboratory conditions. | 2017 | 29246237 |
| insecticide susceptibility screening against culex and aedes (diptera: culicidae) mosquitoes from the united states. | mosquitoes exposed to sublethal doses of insecticides may be selected for resistance to insecticide active ingredients (ais). mosquitoes are exposed to ais through agricultural, public/private mosquito control programs, homeowners, and other sources. hence, mosquito control programs should routinely measure the resistance/susceptibility status of mosquito populations of public health concern. the objectives here were to determine resistance status for six ais used in adult mosquito control in th ... | 2017 | 29186579 |
| involvement of cecropin b in the formation of the aedes aegypti mosquito cuticle. | in this study, we found a mosquito antimicrobial peptide (amp), aedes aegypti cecropin b (aacec b), was expressed constitutively in pupae. knockdown in the pupae of aacec b using double-stranded rna (dsrna) resulted in high mortality, the emergence of deformed adults and an impairment of pharate adult cuticle formation with fewer lamellae being deposited and the helicoidal pattern of the chitin microfibrils being disorganized. simultaneous injection of aacec b dsrna and aacec b peptide into pupa ... | 2017 | 29180688 |
| a peptide signaling system that rapidly enforces paternity in the aedes aegypti mosquito. | female aedes aegypti mosquitoes typically mate only once with one male in their lifetime, a behavior known as "monandry" [1]. this single mating event provisions the female with sufficient sperm to fertilize the >500 eggs she will produce during her ∼4- to 6-week lifespan in the laboratory [2]. successful mating induces lifetime refractoriness to subsequent insemination by other males, enforcing the paternity of the first male [3-5]. ae. aegypti mate in flight near human hosts [6], and females b ... | 2017 | 29174895 |
| the importance of human population characteristics in modeling aedes aegypti distributions and assessing risk of mosquito-borne infectious diseases. | the mosquito aedes aegypti has long been a vector for human illness in the southeastern united states. in the past, it has been responsible for outbreaks of dengue, chikungunya, and yellow fever and, very recently, the zika virus that has been introduced to the region. multiple studies have modeled the geographic distribution of ae. aegypti as a function of climate factors; however, this ignores the importance of humans to the anthropophilic biter. furthermore, ae. aegypti thrives in areas where ... | 2017 | 29167627 |
| determination of the efficiency of diets for larval development in mass rearing aedes aegypti (diptera: culicidae). | larval diet quality and rearing conditions have a direct and irreversible effect on adult traits. therefore, the current study was carried out to optimize the larval diet for mass rearing of aedes aegypti, for sterile insect technique (sit)-based applications in sri lanka. five batches of 750 first instar larvae (l 1) of ae. aegypti were exposed to five different concentrations (2-10%) of international atomic energy agency (iaea) recommended the larval diet. morphological development parameters ... | 2017 | 29166980 |
| biology of two larval morphological phenotypes of aedes aegypti in abidjan, côte d'ivoire. | since 2008, several outbreaks of yellow fever and dengue occurred in abidjan, the economic capital of côte d'ivoire. a better knowledge of the biology of aedes aegypti populations, the main vector of yellow fever and dengue viruses, is necessary to tailor vector control strategies implemented in the city. this study was designed to determine some biological parameters, occurring during the life cycle of two morphological phenotypes of ae. aegypti larvae. mosquitoes were sampled in a suburb of ab ... | 2017 | 29166962 |
| feeding-induced changes in allatostatin-a and short neuropeptide f in the antennal lobes affect odor-mediated host seeking in the yellow fever mosquito, aedes aegypti. | aedes aegypti is a model species in which the endogenous regulation of odor-mediated host seeking behavior has received some attention. sugar feeding and host seeking in female a. aegypti are transiently inhibited following a blood meal. this inhibition is partially mediated by short neuropeptide f (snpf). the paired antennal lobes (als), as the first processing centers for olfactory information, has been shown to play a significant role in the neuropeptidergic regulation of odor-mediated behavi ... | 2017 | 29166650 |
| wolbachia infection alters the relative abundance of resident bacteria in adult aedes aegypti mosquitoes, but not larvae. | insect-symbiont interactions are known to play key roles in host functions and fitness. the common insect endosymbiont wolbachia can reduce the ability of several human pathogens, including arboviruses and the malaria parasite, to replicate in insect hosts. wolbachia does not naturally infect aedes aegypti, the primary vector of dengue virus, but transinfected ae. aegypti have antidengue virus properties and are currently being trialled as a dengue biocontrol strategy. here, we assess the impact ... | 2017 | 29165845 |
| insecticide susceptibility status in mexican populations of stegomyia aegypti (= aedes aegypti): a nationwide assessment. | in mexico, mosquito vector-borne diseases are of public health concern as a result of their impact on human morbidity and mortality. the use of insecticides against adult mosquitoes is one of the most common ways of controlling mosquito population densities. however, the use of these compounds has resulted in the development of insecticide resistance. the aim of this study was to estimate susceptibility to six pyrethroids, two carbamates and two organophosphates in mexican populations of stegomy ... | 2017 | 29165810 |
| larvicidal, histopathological efficacy of penicillium daleae against larvae of culex quinquefasciatus and aedes aegypti plus biotoxicity on artemia nauplii a non-target aquatic organism. | mosquitoes can transmit the terrible diseases to human beings. soil-borne fungal products act as potential source for low-cost chemicals, used for developing eco-friendly control agents against mosquito-vector borne diseases. the prime aim of study was to check the larvicidal potential of fungus mycelia (by ethyl acetate solvent) extract from penicillium daleae (kx387370) against culex quinquefasciatus and aedes aegypti and to test the toxicity of brine shrimp artemia nauplii, by observing the p ... | 2017 | 29163159 |
| functional analysis of glycosylation of zika virus envelope protein. | zika virus (zikv) infection causes devastating congenital abnormities and guillain-barré syndrome. the zikv envelope (e) protein is responsible for viral entry and represents a major determinant for viral pathogenesis. like other flaviviruses, the zikv e protein is glycosylated at amino acid n154. to study the function of e glycosylation, we generated a recombinant n154q zikv that lacks the e glycosylation and analyzed the mutant virus in mammalian and mosquito hosts. in mouse models, the mutant ... | 2017 | 29091758 |
| darker eggs of mosquitoes resist more to dry conditions: melanin enhances serosal cuticle contribution in egg resistance to desiccation in aedes, anopheles and culex vectors. | mosquito vectors lay their white eggs in the aquatic milieu. during early embryogenesis water passes freely through the transparent eggshell, which at this moment is composed of exochorion and endochorion. within two hours the endochorion darkens via melanization but even so eggs shrink and perish if removed from moisture. however, during mid-embryogenesis, cells of the extraembryonic serosa secrete the serosal cuticle, localized right below the endochorion, becoming the third and innermost eggs ... | 2017 | 29084225 |
| assessing the population at risk of zika virus in asia - is the emergency really over? | on november 18, 2016, the who ended its designation of the zika virus (zikv) epidemic as a public health emergency of international concern (pheic). at the same time, zikv transmission continues in asia, with the number of asian countries reporting zika cases increasing over the last 2 years. applying a method that combines epidemiological theory with data on epidemic size and drivers of transmission, we characterised the population at risk of zikv infection from aedes aegypti mosquitoes in 15 c ... | 2017 | 29082009 |
| culex quinquefasciatus mosquitoes do not support replication of zika virus. | the rapid spread of zika virus (zikv) in the americas raised many questions about the role of culex quinquefasciatus mosquitoes in transmission, in addition to the key role played by the vector aedes aegypti. here we analysed the competence of cx. quinquefasciatus (with or without wolbachia endosymbionts) for a zikv isolate. we also examined the induction of rna interference pathways after viral challenge and the production of small virus-derived rnas. we did not observe any infection nor such s ... | 2017 | 29076805 |
| voltage-sensitive sodium channel mutations s989p + v1016g in aedes aegypti confer variable resistance to pyrethroids, ddt and oxadiazines. | aedes aegypti is a vector of several important human pathogens. control efforts rely primarily on pyrethroid insecticides for adult mosquito control, especially during disease outbreaks. a. aegypti has developed resistance nearly everywhere it occurs and insecticides are used. an important mechanism of resistance is due to mutations in the voltage-sensitive sodium channel (vssc) gene. two mutations, in particular, s989p + v1016g, commonly occur together in parts of asia. | 2017 | 29064635 |
| asymmetrical competition between aedes aegypti and culex quinquefasciatus (diptera: culicidae) coexisting in breeding sites. | aedes aegypti and culex quinquefasciatus are mosquito vectors for several tropical diseases that represent a current public health problem. the ecological requirements for each species are different, however, both species show high biological adaptability, which promotes their coexistence in the same breeding sites. the purpose of this study was to assess the effect of larval association between ae. aegypti and cx. quinquefasciatus under different laboratory conditions of food supply and tempera ... | 2017 | 29064390 |
| assessment of the insecticidal activity of afoxolaner against aedes aegypti in dogs treated with nexgard®. | twelve healthy dogs were studied in this parallel group, blinded, randomised, and negative controlled efficacy study. on day -1, the 12 dogs included were ranked within sex in descending order of individual pre-treatment (day -5) fed mosquito counts and randomly allocated by blocks of two dogs to the untreated control group or the afoxolaner-treated group. nexgard® (merial, now part of boehringer ingelheim animal health) was administered orally on day 0 in accordance with the european label inst ... | 2017 | 29063828 |
| synthesis and chemometrics of thymol and carvacrol derivatives as larvicides against aedes aegypti. | thymol and carvacrol have previously demonstrated larvicidal activity against aedes aegypti (diptera: culicidae). in view of this fact, it was of our interest to obtain synthetic derivatives and evaluate their larvicidal activity on ae. aegypti larvae. | 2017 | 29062856 |
| evaluation of larvicidal activity of essential oil from leaves of coccinia grandis against three mosquito species. | to study the chemical constituents and larvicidal activity of essential oil extracted from the leaves of coccinia grandis against three mosquito species. | 2017 | 29062847 |
| use of a recombinant mosquito densovirus as a gene delivery vector for the functional analysis of genes in mosquito larvae. | in vivo microinjection is the most commonly used gene transfer technique for analyzing the gene functions in individual mosquitoes. however, this method requires a more technically demanding operation and involves complicated procedures, especially when used in larvae due to their small size, relatively thin and fragile cuticle, and high mortality, which limit its application. in contrast, viral vectors for gene delivery have been developed to surmount extracellular and intracellular barriers. t ... | 2017 | 29053694 |
| using phage display technology to obtain crybodies active against non-target insects. | the insecticidal cry toxins produced by bacillus thuringiensis (bt) are increasingly important in the biological control of insect pests and vectors of human disease. markets for bt products and transgenic plants expressing their toxins are driven by their specificity, safety and the move away from chemical control agents. however, the high specificity of cry toxins can also prove to be a limitation when there is no known cry toxin active against a particular target. novel activities can be disc ... | 2017 | 29097681 |
| efficiency of two larval diets for mass-rearing of the mosquito aedes aegypti. | aedes aegypti is a major vector of arboviruses that may be controlled on an area-wide basis using the sterile insect technique (sit). larval diet is a major factor in mass-rearing for sit programs. we compared dietary effects on immature development and adult fitness-related characteristics for an international atomic energy agency (iaea) diet, developed for rearing ae. albopictus, and a standardized laboratory rodent diet (lrd), under a 14:10 h (light:dark) photoperiod ("light" treatment) or co ... | 2017 | 29095933 |