Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| novel wolbachia-transinfected aedes aegypti mosquitoes possess diverse fitness and vector competence phenotypes. | wolbachia pipientis from drosophila melanogaster (wmel) is an endosymbiotic bacterium that restricts transmission of human pathogenic flaviviruses and alphaviruses, including dengue, zika, and chikungunya viruses, when introduced into the mosquito vector aedes aegypti. to date, wmel-infected ae. aegypti have been released in field trials in 5 countries to evaluate the effectiveness of this strategy for disease control. despite the success in establishing wmel-infected mosquitoes in wild populati ... | 2017 | 29216317 |
| dengue serotype-specific immune response in aedes aegypti and aedes albopictus. | dengue viruses (denv) are considered one of the most important emerging pathogens and dengue disease is a global health threat. the geographic expansion of dengue viruses has led to co-circulation of all four dengue serotypes making it imperative that new denv control strategies be devised. | 2017 | 29211244 |
| an aedes aegypti-associated fungus increases susceptibility to dengue virus by modulating gut trypsin activity. | transmission of dengue virus (denv) requires successful completion of the infection cycle in the aedes aegypti vector, which is initiated in the midgut tissue after ingestion of an infectious blood meal. while certain ae. aegypti midgut-associated bacteria influence virus infection, little is known about the midgut-associated fungi (mycobiota), and how its members might influence susceptibility to denv infection. we show that a talaromyces (tsp_pr) fungus, isolated from field-caught ae. aegypti, ... | 2017 | 29205153 |
| alternative patterns of sex chromosome differentiation in aedes aegypti (l). | some populations of west african aedes aegypti, the dengue and zika vector, are reproductively incompatible; our earlier study showed that divergence and rearrangements of genes on chromosome 1, which bears the sex locus (m), may be involved. we also previously described a proposed cryptic subspecies senaae (pk10, senegal) that had many more high inter-sex fst genes on chromosome 1 than did ae.aegypti aegypti (aaa, pai lom, thailand). the current work more thoroughly explores the significance of ... | 2017 | 29202694 |
| global transcriptome analysis of aedes aegypti mosquitoes in response to zika virus infection. | zika virus (zikv) of the flaviviridae family is a recently emerged mosquito-borne virus that has been implicated in the surge of the number of microcephaly instances in south america. the recent rapid spread of the virus led to its declaration as a global health emergency by the world health organization. the virus is transmitted mainly by the mosquito aedes aegypti, which is also the vector of dengue virus; however, little is known about the interactions of the virus with the mosquito vector. i ... | 2017 | 29202041 |
| global risk mapping for major diseases transmitted by aedes aegypti and aedes albopictus. | the objective of this study was to map the global risk of the major arboviral diseases transmitted by aedes aegypti and aedes albopictus by identifying areas where the diseases are reported, either through active transmission or travel-related outbreaks, as well as areas where the diseases are not currently reported but are nonetheless suitable for the vector. | 2017 | 29196275 |
| larvicidal and residual activity of imidazolium salts against aedes aegypti (diptera: culicidae). | aedes aegypti is an important species of mosquito, which can transmit several arboviruses such as dengue fever, yellow fever, chikungunya, and zika. as these mosquitoes are becoming resistant to most chemical insecticides used in the world, studies with new larvicides should be prioritized. based on the known biological profile of imidazolium salts (is), the objective of this study was to evaluate the potential of six is as larvicides against ae. aegypti, which was tested against ae. aegypti lar ... | 2017 | 29193680 |
| first insights on insecticidal activity upon aedes aegypti and partial biochemical characterization of a novel low molecular mass chymotrypsin-trypsin inhibitor purified from lonchocarpus sericeus seeds. | arboviroses such as dengue, zika and chikungunya represent a serious issue in public health due to the absence of approved vaccine or specific antiviral drugs. one way to prevent these diseases is by combating the vector mosquito, aedes aegypti (diptera), which has serine proteases in the midgut. protease inhibitors are molecules that can block enzyme activity impairing digestion and nutrition that can lead to death. thus, we purified and characterized a novel chymotrypsin- trypsin inhibitor fro ... | 2017 | 29193604 |
| modelling dengue fever risk in the state of yucatan, mexico using regional-scale satellite-derived sea surface temperature. | accurately predicting vector-borne diseases, such as dengue fever, is essential for communities worldwide. changes in environmental parameters such as precipitation, air temperature, and humidity are known to influence dengue fever dynamics. furthermore, previous studies have shown how oceanographic variables, such as el niño southern oscillation (enso)-related sea surface temperature from the pacific ocean, influences dengue fever in the americas. however, literature is lacking on the use of re ... | 2017 | 28450208 |
| detecting the impact of temperature on transmission of zika, dengue, and chikungunya using mechanistic models. | recent epidemics of zika, dengue, and chikungunya have heightened the need to understand the seasonal and geographic range of transmission by aedes aegypti and ae. albopictus mosquitoes. we use mechanistic transmission models to derive predictions for how the probability and magnitude of transmission for zika, chikungunya, and dengue change with mean temperature, and we show that these predictions are well matched by human case data. across all three viruses, models and human case data both show ... | 2017 | 28448507 |
| juvenile hormone and its receptor methoprene-tolerant promote ribosomal biogenesis and vitellogenesis in the aedes aegypti mosquito. | juvenile hormone (jh) controls many biological activities in insects, including development, metamorphosis, and reproduction. in the aedes aegypti mosquito, a vector of dengue, yellow fever, chikungunya, and zika viruses, the metabolic tissue (the fat body, which is an analogue of the vertebrate liver) produces yolk proteins for developing oocytes. jh is important for the fat body to acquire competence for yolk protein production. however, the molecular mechanisms of how jh promotes mosquito rep ... | 2017 | 28446607 |
| species abundance and temporal variation of arbovirus vectors in brownsville, texas. | the recent outbreaks of the dengue fever and west nile viruses and the looming threats of the zika and chikungunya viruses highlight the importance of establishing effective, proactive arboviral surveillance in communities at high risk of transmission, such as those on the texas-mexico border. currently, there are no approved human vaccines available for these mosquito-borne diseases, so entomological control and case management are the only known methods for decreasing disease incidence. the pr ... | 2017 | 28444003 |
| dengue virus replicates and accumulates in aedes aegypti salivary glands. | dengue virus (denv) is an rna virus transmitted among humans by mosquito vectors, mainly aedes aegypti. denv transmission requires viral dissemination from the mosquito midgut to the salivary glands. during this process the virus undergoes several population bottlenecks, which are stochastic reductions in population size that restrict intra-host viral genetic diversity and limit the efficiency of natural selection. despite the implications for virus transmission and evolution, denv replication i ... | 2017 | 28431281 |
| yellow fever from angola and congo: a storm gathers. | in common with zika, chikungunya and dengue, yellow fever (yf) is an arthropod-borne flavivirus. it is transmitted between humans and from monkeys by mosquitoes of the aedes aegypti (its principal vector), haemogogus and albopictus varieties. three cycles of transmission may occur: urban; sylvatic; and intermediate. recently, sub-saharan africa has seen the resurgence of this neglected disease. the current yf outbreak in angola began in december 2015 in the capital luanda and by october 2016 the ... | 2017 | 28424031 |
| detection of a new pyrethroid resistance mutation (v410l) in the sodium channel of aedes aegypti: a potential challenge for mosquito control. | the yellow fever mosquito, aedes aegypti, particularly in neotropical regions, is the principal vector of dengue, yellow fever, zika and chikungunya viruses. pyrethroids remain one of the most used insecticides to control aedes mosquitoes, despite the development of pyrethroid resistance in many mosquito populations worldwide. here, we report a brazilian strain of a. aegypti with high levels (approximately 100-60,000 fold) of resistance to both type i and type ii pyrethroids. we detected two mut ... | 2017 | 28422157 |
| deploying dengue-suppressing wolbachia : robust models predict slow but effective spatial spread in aedes aegypti. | a novel strategy for controlling the spread of arboviral diseases such as dengue, zika and chikungunya is to transform mosquito populations with virus-suppressing wolbachia. in general, wolbachia transinfected into mosquitoes induce fitness costs through lower viability or fecundity. these maternally inherited bacteria also produce a frequency-dependent advantage for infected females by inducing cytoplasmic incompatibility (ci), which kills the embryos produced by uninfected females mated to inf ... | 2017 | 28411063 |
| severe dengue due to secondary hemophagocytic lymphohistiocytosis: a case study. | dengue, transmitted by the mosquito aedes aegypti affects millions of people worldwide every year. dengue induced hemophagocytic lymphohistiocytosis (hlh) is a serious condition and may prove fatal if not detected early and treated appropriately. diagnosis of hlh is challenging and usually missed as clinical and laboratory findings are nonspecific. moreover, the pathophysiology of the systemic inflammatory response syndrome and/or sepsis is remarkably similar to hlh. secondary hlh following infe ... | 2017 | 28409119 |
| vector competence and innate immune responses to dengue virus infection in selected laboratory and field-collected stegomyia aegypti (= aedes aegypti). | control of dengue virus (denv) transmission, primarily based on strategies to reduce populations of the principle vector stegomya aegypti (= aedes aegypti) (diptera: culicidae), is difficult to sustain over time. other potential strategies aim to manipulate characteristics such as vector competence (vc), the innate capacity of the vector to transmit the virus. previous studies have identified genetic factors, including differential expression of apoptosis-related genes, associated with the refra ... | 2017 | 28407282 |
| advances in vector control science: rear-and-release strategies show promise… but don't forget the basics. | both chikungunya and zika viruses have recently swept from africa across the pacific to the americas, causing major outbreaks of disease in humans. in the meantime, dengue epidemics continue throughout the tropics. traditional vector control programs based on strategies from 1950s and 1960s have been relatively ineffective in combating recent epidemics. in response, new methods involving the rearing and releasing of large numbers of mosquitoes to eliminate or modify local aedes populations are b ... | 2017 | 28403439 |
| aedes aegypti (diptera: culicidae) abundance model improved with relative humidity and precipitation-driven egg hatching. | we propose an improved aedes aegypti (l.) abundance model that takes into account the effect of relative humidity (rh) on adult survival, as well as rainfall-triggered egg hatching. the model uses temperature-dependent development rates described in the literature as well as documented estimates for mosquito survival in environments with high rh, and for egg desiccation. we show that combining the two additional components leads to better agreement with surveillance trap data and with dengue inc ... | 2017 | 28402546 |
| repellency of 29 synthetic and natural commercial topical insect repellents against aedes aegypti (diptera: culicidae) in central mexico. | in mexico, the use of repellents to prevent insects from landing and biting is a common practice. however, variation in the efficiency of natural and synthetic repellents has been observed. in this study, we evaluated the repellency and protection time of 16 synthetic and 13 natural-based commercial products against aedes aegypti (l.) from an endemic dengue area (jojutla, morelos) in central mexico. the "arm exposure" cage test was used to assess the efficacy of the repellents. tests were conduc ... | 2017 | 28402436 |
| why is aedes aegypti linnaeus so successful as a species? | diseases transmitted by mosquitoes impose enormous burden towards human morbidity and mortality. over the last three decades, brazil has suffered from severe dengue epidemics. in september 2014, this situation is further complicated by the introduction of two other viruses, zika and chikungunya, placing brazil in a triple epidemic. in this article, we discuss the biology of aedes aegypti linnaeus, and the principal initiatives currently used to control mosquito populations and the diseases they ... | 2017 | 28401481 |
| zika virus alters the microrna expression profile and elicits an rnai response in aedes aegypti mosquitoes. | zika virus (zikv), a flavivirus transmitted primarily by aedes aegypti, has recently spread globally in an unprecedented fashion, yet we have a poor understanding of host-microbe interactions in this system. to gain insights into the interplay between zikv and the mosquito, we sequenced the small rna profiles in zikv-infected and non-infected ae. aegypti mosquitoes at 2, 7 and 14 days post-infection. zika induced an rnai response in the mosquito with virus-derived short interfering rnas and piwi ... | 2017 | 28715413 |
| biopolymer zein-coated gold nanoparticles: synthesis, antibacterial potential, toxicity and histopathological effects against the zika virus vector aedes aegypti. | the control of multidrug-resistant bacteria as well as insect pests and vectors is timely and important now a days. the present study was designed to evaluate the in vitro antibacterial, antibiofilm and mosquito larvicidal effects of gold nanoparticles synthesized using the zein biopolymer (ze-aunps) against gram positive (bacillus pumilus and bacillus subtilis), gram negative (shigella sonnei and pseudomonas aeruginosa) bacteria and third instar larvae of the dengue and zika virus vector aedes ... | 2017 | 28654862 |
| cell fusing agent virus and dengue virus mutually interact in aedes aegypti cell lines. | the genus flavivirus contains more than 70 single-stranded, positive-sense arthropod-borne rna viruses. some flaviviruses are particularly medically important to humans and other vertebrates including dengue virus (denv), west nile virus, and yellow fever virus. these viruses are transmitted to vertebrates by mosquitoes and other arthropod species. mosquitoes are also infected by insect-specific flaviviruses (isfs) that do not appear to be infective to vertebrates. cell fusing agent virus (cfav) ... | 2017 | 28761113 |
| experimental infection with and maintenance of cell fusing agent virus (flavivirus) in aedes aegypti. | during the past two decades, there has been a dramatic increase in the recognition and characterization of novel insect-specific flaviviruses (isfvs). some of these agents are closely related to important mosquito-borne flavivirus pathogens. results of experimental studies suggest that mosquitoes and mosquito cell cultures infected with some isfvs are refractory to superinfection with related flavivirus pathogens; and it has been proposed that isfvs potentially could be used to alter the vector ... | 2017 | 28719335 |
| activation of aedes aegypti prophenoloxidase-3 and its role in the immune response against entomopathogenic fungi. | serine protease cascade-mediated melanization is an important innate immune response in insects and crustaceans, which involves the proteolytic activation of prophenoloxidase (ppo). in this study, we investigated the role of aedes aegypti ppo3 in antifungal immune defence. we expressed and purified recombinant ppo3 (rppo3) in escherichia coli and demonstrated that rppo3 was activated by ethanol and, to a lesser extent, by cetylpyridinium chloride. in the presence of cu(2+) , rppo3 exhibited enzy ... | 2017 | 28556276 |
| understanding the role of micrornas in the interaction of aedes aegypti mosquitoes with an insect-specific flavivirus. | the flavivirus genus contains some of the most prevalent vector-borne viruses, such as the dengue, zika and yellow fever viruses that cause devastating diseases in humans. however, the insect-specific clade of flaviviruses is restricted to mosquito hosts, albeit they have retained the general features of the genus, such as genome structure and replication. the interactions between insect-specific flaviviruses (isfs) and their mosquito hosts are largely unknown. pathogenic flaviviruses are known ... | 2017 | 28699859 |
| dengue vectors in urban and suburban assam, india: entomological observations. | dengue is rapidly becoming established in north-east india and spreading, on account of rapid urbanization and population movement, with reported morbidity and attributable death cases. this study aims to determine the seasonal abundance of aedes (stegomyia) albopictus and aedes (stegomyia) aegypti in guwahati metropolis and suburban settlements; to characterize the breeding resources for these mosquitoes; and to ascertain the status of their susceptibility to adulticides and larvicides. | 2017 | 28607255 |
| copper ii - polar amino acid complexes: toxicity to bacteria and larvae of aedes aegypti. | control strategies using insecticides are sometimes ineffective due to the resistance of the insect vectors.in this scenario new products must be proposed for the control of insect vectors.the complexes l-aspartate cu (ii) and l-glutamate-cu (ii) complexes were synthesized and characterized by elemental analysis, visible ultraviolet, infrared spectroscopy and potentiometric titration. the toxicity of these complexes was analyzed in aedes aegypti (diptera: culicidae) larvae and gram-negative and ... | 2017 | 28746551 |
| jaburetox: update on a urease-derived peptide. | urease from canavalia ensiformis seeds was the first enzyme ever to be crystallized, in 1926. these proteins, found in plants, bacteria and fungi, present different biological properties including catalytic hydrolysis of urea, and also enzyme-independent activities, such as induction of exocytosis, pro-inflammatory effects, neurotoxicity, antifungal and insecticidal properties. urease is toxic to insects and fungi per se but part of this toxicity relies on an internal peptide (~11 kda), which is ... | 2017 | 28638403 |
| bacteria-mediated hypoxia functions as a signal for mosquito development. | mosquitoes host communities of microbes in their digestive tract that consist primarily of bacteria. we previously reported that several mosquito species, including aedes aegypti, do not develop beyond the first instar when fed a nutritionally complete diet in the absence of a gut microbiota. in contrast, several species of bacteria, including escherichia coli, rescue development of axenic larvae into adults. the molecular mechanisms underlying bacteria-dependent growth are unknown. here, we des ... | 2017 | 28630299 |
| new insights into hcv replication in original cells from aedes mosquitoes. | the existing literature about hcv association with, and replication in mosquitoes is extremely poor. to fill this gap, we performed cellular investigations aimed at exploring (i) the capacity of hcv e1e2 glycoproteins to bind on aedes mosquito cells and (ii) the ability of hcv serum particles (hcvsp) to replicate in these cell lines. | 2017 | 28830495 |
| larvicidal potency of marine actinobacteria isolated from mangrove environment against aedes aegypti and anopheles stephensi. | the marine soil samples were collected from different locations of parangipettai mangrove ecosystem, vellar estuary, southeast coast of india. totally 30 different marine actinobacteria were isolated by serial dilution plate technique on starch casein agar medium. the isolated actinobacteria were investigated for their larvicidal activity against aedes aegypti and anopheles stephensi mosquitoes. streptomyces fungicidicus, s. griseus, s. albus, s. alboflavus and s. rochei were identified as poten ... | 2017 | 28615847 |
| efficacy of the vegetative cells of lysinibacillus sphaericus for biological control of insecticide-resistant aedes aegypti. | the control of aedes aegypti is usually based on chemical insecticides, but the overuse of these compounds has led to increased resistance. the binary toxin produced by lysinibacillus sphaericus in the final stages of sporulation is used for mosquito control due to its specificity against the culicid larvae; however, it has been proved that ae. aegypti is refractory for this toxin. currently, there is no evidence of the use of l. sphaericus vegetative cells for mosquito biocontrol. therefore, in ... | 2017 | 28490350 |
| mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of buruli ulcer. | addressing the transmission enigma of the neglected disease buruli ulcer (bu) is a world health organization priority. in australia, we have observed an association between mosquitoes harboring the causative agent, mycobacterium ulcerans, and bu. here we tested a contaminated skin model of bu transmission by dipping the tails from healthy mice in cultures of the causative agent, mycobacterium ulcerans. tails were exposed to mosquito (aedes notoscriptus and aedes aegypti) blood feeding or punctur ... | 2017 | 28410412 |
| vector competence of aedes albopictus (skuse) and aedes aegypti (linnaeus) for plasmodium gallinaceum infection and transmission. | avian malaria caused by plasmodium gallinaceum is an important mosquito-borne disease. eradication of this disease remains problematic since its competent vectors are diverse and widely distributed across the globe. several mosquito species were implicated as competent vectors for this parasite. however, studies on vector competence for p. gallinaceum remain limited. in this study, vector competence in the two most predominant mosquito vectors in tropical countries, aedes albopictus and ae. aegy ... | 2017 | 28579025 |
| synergistic efficacy of aedes aegypti antimicrobial peptide cecropin a2 and tetracycline against pseudomonas aeruginosa. | the increasing prevalence of antibiotic resistance has created an urgent need for alternative drugs with new mechanisms of action. antimicrobial peptides (amps) are promising candidates that could address the spread of multidrug-resistant bacteria, either alone or in combination with conventional antibiotics. we studied the antimicrobial efficacy and bactericidal mechanism of cecropin a2, a 36-residue α-helical cationic peptide derived from aedes aegypti cecropin a, focusing on the common pathog ... | 2017 | 28483966 |
| aedes aegypti piwi4 is a noncanonical piwi protein involved in antiviral responses. | the small interfering rna (sirna) pathway is a major antiviral response in mosquitoes; however, another rna interference pathway, the piwi-interacting rna (pirna) pathway, has been suggested to be antiviral in mosquitoes. piwi4 has been reported to be a key mediator of this response in mosquitoes, but it is not involved in the production of virus-specific pirnas. here, we show that piwi4 associates with members of the antiviral exogenous sirna pathway (ago2 and dcr2), as well as with proteins of ... | 2017 | 28497119 |
| characterization of tolypocladium cylindrosporum (hypocreales: ophiocordycipitaceae) and its impact against aedes aegypti and aedes albopictus eggs at low temperature. | we examined the growth characteristics of tolypocladium cylindrosporum ibt 41712 and its potential to infect eggs of aedes aegypti and ae. albopictus at a low temperature (15°c). when grown on sabouraud dextrose agar supplemented with yeast extract, the ibt 41712 formed white colonies turning to a slightly darker, off-white color when mature. the mycelia bore swollen conidiophores producing smooth-walled, oblong to cylindrical conidia with varying sizes, ranging from 1.5 to 3.5 μm long. to deter ... | 2017 | 28854112 |
| the role of the environment in the evolution of tolerance and resistance to a pathogen. | defense against parasites can be divided into resistance, which limits parasite burden, and tolerance, which reduces pathogenesis at a given parasite burden. distinguishing between the two and understanding which defense is favored by evolution in different ecological settings are important, as they lead to fundamentally different evolutionary trajectories of host-parasite interactions. we let the mosquito aedes aegypti evolve under different food levels and with either no parasite, a constant p ... | 2017 | 28829641 |
| specificity and putative mode of action of a mosquito larvicidal toxin from the bacterium xenorhabdus innexi. | reduction of mosquito-borne diseases relies, in part, on the use of synthetic pesticides to control pest mosquitoes. this reliance has led to genetic resistance, environmental contamination and the nondiscriminatory elimination of both pest and non-pest species. to expand our options for control, we screened entomopathogenic bacteria for potential larvicidal activity. a lipopeptide from the bacterium, xenorhabdus innexi, was discovered that displayed potent larvicidal activity. the lc50s of the ... | 2017 | 28712711 |
| potential risk of re-emergence of urban transmission of yellow fever virus in brazil facilitated by competent aedes populations. | yellow fever virus (yfv) causing a deadly viral disease is transmitted by the bite of infected mosquitoes. in brazil, yfv is restricted to a forest cycle maintained between non-human primates and forest-canopy mosquitoes, where humans can be tangentially infected. since late 2016, a growing number of human cases have been reported in southeastern brazil at the gates of the most populated areas of south america, the atlantic coast, with rio de janeiro state hosting nearly 16 million people. we sh ... | 2017 | 28687779 |
| taking innovative vector control interventions in urban latin america to scale: lessons learnt from multi-country implementation research. | prior to the current public health emergency following the emergence of chikungunya and zika virus disease in the americas during 2014 and 2015, multi-country research investigated between 2011 and 2013 the efficacy of novel aedes aegypti intervention packages through cluster randomised controlled trials in four latin-american cities: fortaleza (brazil); girardot (colombia), acapulco (mexico) and salto (uruguay). results from the trials led to a scaling up effort of the interventions at city lev ... | 2017 | 28829235 |
| modeling the transmission and control of zika in brazil. | zika virus, a reemerging mosquito-borne flavivirus, started spread across central and southern america and more recently to north america. the most serious impacted country is brazil. based on the transmission mechanism of the virus and assessment of the limited data on the reported suspected cases, we establish a dynamical model which allows us to estimate the basic reproduction number r 0 = 2.5020. the wild spreading of the virus make it a great challenge to public health to control and preven ... | 2017 | 28798323 |
| differential outcomes of zika virus infection in aedes aegypti orally challenged with infectious blood meals and infectious protein meals. | infection of mosquitoes is an essential step for the transmission of mosquito-borne arboviruses in nature. engorgement of infectious blood meals from viremic infected vertebrate hosts allows the entry of viruses and initiates infection of midgut epithelial cells. historically, the infection process of arboviruses in mosquitoes has been studied through the engorgement of mosquitoes from viremic laboratory animals or from artificial feeders containing blood mixed with viruses harvested from cell c ... | 2017 | 28796799 |
| zika virus replication in the mosquito culex quinquefasciatus in brazil. | zika virus (zikv) is a flavivirus that has recently been associated with an increased incidence of neonatal microcephaly and other neurological disorders. the virus is primarily transmitted by mosquito bite, although other routes of infection have been implicated in some cases. the aedes aegypti mosquito is considered to be the main vector to humans worldwide; however, there is evidence that other mosquito species, including culex quinquefasciatus, transmit the virus. to test the potential of cx ... | 2017 | 28790458 |
| sexual and vertical transmission of zika virus in anti-interferon receptor-treated rag1-deficient mice. | although zika virus (zikv) is primarily transmitted to humans by the aedes aegypti mosquito, human-to-human transmission has also been observed from males-to-females as well as mother-to-offspring. in the current study, we studied both sexual transmission (stx) and vertical transmission (vtx) of zikv using anti-ifnar1-treatment of rag1 (-/-) (air) mice. these mice have suppressed type i ifn responses and lack adaptive immune responses, leading to a prolonged infection prior to clinical disease. ... | 2017 | 28775298 |
| culex quinquefasciatus from areas with the highest incidence of microcephaly associated with zika virus infections in the northeast region of brazil are refractory to the virus. | zika virus (zikv) is widely distributed in brazil and the northeast region (ne) is the most affected zone, showing the highest incidence of microcephaly associated with zikv congenital infections worldwide. we report attempts to infect three populations of culex quinquefasciatus from severely affected sites in the ne and southeast region (se) of brazil with three strains of zikv isolated from these localities. an aedes aegypti population from the se was used as a positive control. all tested cx. ... | 2017 | 28767975 |
| linking only aedes aegypti with zika virus has world-wide public health implications. | 2017 | 28736548 | |
| zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process. | zika disease has transformed into a serious global health problem due to the rapid spread of the arbovirus and alarming severity including congenital complications, microcephaly and guillain-barré syndrome. zika virus (zikv) is primarily transmitted to humans through the bite of an infective mosquito, with aedes aegypti being the main vector. | 2017 | 28728607 |
| asymptomatic transmission and the dynamics of zika infection. | following the 2013-14 outbreak in french polynesia, the zika virus (zikv) epidemic spread widely to many countries where aedes aegypti as the main transmitting vector is endemic. the lack of a second wave of zikv infection in most affected regions may suggest that a sufficiently high level of herd immunity was reached during the first wave. we developed an agent-based transmission model to investigate the role of asymptomatic infection on the likelihood of observing a second wave, while accounti ... | 2017 | 28724972 |
| american aedes vexans mosquitoes are competent vectors of zika virus. | abstractstarting in 2013-2014, the americas have experienced a massive outbreak of zika virus (zikv) which has now reached at least 49 countries. although most cases have occurred in south america and the caribbean, imported and autochthonous cases have occurred in the united states. aedes aegypti and aedes albopictus mosquitoes are known vectors of zikv. little is known about the potential for temperate aedes mosquitoes to transmit zikv. aedes vexans has a worldwide distribution, is highly abun ... | 2017 | 28719283 |
| early evidence for zika virus circulation among aedes aegypti mosquitoes, rio de janeiro, brazil. | during 2014-2016, we conducted mosquito-based zika virus surveillance in rio de janeiro, brazil. results suggest that zika virus was probably introduced into the area during may-november 2013 via multiple in-country sources. furthermore, our results strengthen the hypothesis that zika virus in the americas originated in brazil during october 2012-may 2013. | 2017 | 28628464 |
| a single substitution changes zika virus infectivity in mosquitoes. | zika virus (zikv) has caused outbreaks in the pacific and the americas. the mechanism underlying the recent zikv epidemic remains obscure. a recent study reveals that an amino acid substitution is associated with increased infectivity of zikv in the aedes aegypti mosquito. | 2017 | 28610876 |
| zika vector transmission risk in temperate australia: a vector competence study. | zika virus is an emerging pathogen of global importance. it has been responsible for recent outbreaks in the americas and in the pacific region. this study assessed five different mosquito species from the temperate climatic zone in australia and included aedes albopictus as a potentially invasive species. | 2017 | 28599659 |
| emerging infectious disease agents and blood safety in australia: spotlight on zika virus. | emerging infectious diseases (eids) are infectious diseases whose incidence has increased in humans in the past 20 years or could increase in the near future. eid agents may represent a threat to blood safety if they infect humans, cause a clinically significant illness, include an asymptomatic blood phase in the course of infection, and are transmissible by transfusion. eid agents are typically not well characterised, but there is a consensus that we can expect ongoing outbreaks. strategies to ... | 2017 | 28566073 |
| genomic epidemiology reveals multiple introductions of zika virus into the united states. | zika virus (zikv) is causing an unprecedented epidemic linked to severe congenital abnormalities. in july 2016, mosquito-borne zikv transmission was reported in the continental united states; since then, hundreds of locally acquired infections have been reported in florida. to gain insights into the timing, source, and likely route(s) of zikv introduction, we tracked the virus from its first detection in florida by sequencing zikv genomes from infected patients and aedes aegypti mosquitoes. we s ... | 2017 | 28538723 |
| de novo generation and characterization of new zika virus isolate using sequence data from a microcephaly case. | zika virus (zikv) has recently emerged and is the etiological agent of congenital zika syndrome (czs), a spectrum of congenital abnormalities arising from neural tissue infections in utero. herein, we describe the de novo generation of a new zikv isolate, zikvnatal, using a modified circular polymerase extension reaction protocol and sequence data obtained from a zikv-infected fetus with microcephaly. zikvnatal thus has no laboratory passage history and is unequivocally associated with czs. zikv ... | 2017 | 28529976 |
| outbreak of zika virus infection in singapore: an epidemiological, entomological, virological, and clinical analysis. | an outbreak of zika virus infection was detected in singapore in august, 2016. we report the first comprehensive analysis of a national response to an outbreak of zika virus infection in asia. | 2017 | 28527892 |
| eco-friendly and cost-effective ag nanocrystals fabricated using the leaf extract of habenaria plantaginea: toxicity on six mosquito vectors and four non-target species. | recently, the biofabrication of metal nanoparticles has gained wide interest owing to its inherent features such as swift, simplicity, eco-friendliness, and cheaper costs. different green-reducing agents led to the production of nanoparticles with varying toxicity on insects. in the current study, silver nanoparticles (agnps) were successfully synthesized using habenaria plantaginea leaf extract. ag nanoparticles were studied by uv-vis spectroscopy (uv-vis), x-ray diffraction (xrd), fourier tran ... | 2017 | 28523613 |
| evolutionary enhancement of zika virus infectivity in aedes aegypti mosquitoes. | zika virus (zikv) remained obscure until the recent explosive outbreaks in french polynesia (2013-2014) and south america (2015-2016). phylogenetic studies have shown that zikv has evolved into african and asian lineages. the asian lineage of zikv was responsible for the recent epidemics in the americas. however, the underlying mechanisms through which zikv rapidly and explosively spread from asia to the americas are unclear. non-structural protein 1 (ns1) facilitates flavivirus acquisition by m ... | 2017 | 28514450 |
| a location-specific spreadsheet for estimating zika risk and timing for zika vector surveillance, using us military facilities as an example. | local zika virus transmission in the united states involving one or both of the known vector species, aedes aegypti and ae. albopictus, is of major concern. to assist efforts to anticipate the risks of transmission, we developed an excel spreadsheet tool that uses vector and virus temperature thresholds, remotely sensed maximum temperature, and habitat suitability models to answer the questions: "is zika transmission likely here?" and "when should we conduct vector surveillance?" an example spre ... | 2017 | 28511272 |
| transmission incompetence of culex quinquefasciatus and culex pipiens pipiens from north america for zika virus. | abstractin late 2014, zika virus (zikv; flaviviridae, flavivirus) emerged as a significant arboviral disease threat in the western hemisphere. aedes aegypti and aedes albopictus have been considered the principal vectors of zikv in the new world due to viral isolation frequency and vector competence assessments. limited reports of culex transmission potential have highlighted the need for additional vector competence assessments of north american culex species. accordingly, north american culex ... | 2017 | 28500817 |
| potential of a northern population of aedes vexans (diptera: culicidae) to transmit zika virus. | zika virus is an emerging arbovirus of humans in the western hemisphere. with its potential spread into new geographical areas, it is important to define the vector competence of native mosquito species. we tested the vector competency of aedes vexans (meigen) from the lake agassiz plain of northwestern minnesota and northeastern north dakota. aedes aegypti (l.) was used as a positive control for comparison. mosquitoes were fed blood containing zika virus and 2 wk later were tested for viral inf ... | 2017 | 28499036 |
| a zika virus from america is more efficiently transmitted than an asian virus by aedes aegypti mosquitoes from asia. | zika is a mosquito-borne disease associated with neurological disorders that causes an on-going pandemic. the first outbreak was recorded in micronesia in 2007, then in french polynesia in 2014 from which it spread to south america in 2015 and ignited a widespread epidemic. interestingly, zika outbreaks in asia remained of moderate intensity although the virus is circulating. to understand these epidemiological variations, we investigated the entomological determinants of zikv transmission in as ... | 2017 | 28450714 |
| vector competence and transovarial transmission of two aedes aegypti strains to zika virus. | zika virus (zikv) has become a serious threat to global health since the outbreak in brazil in 2015. additional chinese cases have continuously been reported since the first case of laboratory-confirmed zikv infection in china on 6 february 2016. aedes aegypti is the most important vector for zikv. this study shows that two strains from china exhibit high levels of midgut infection and highly disseminated infection of salivary glands and ovaries. both strains can transmit zikv to infant mice bit ... | 2017 | 28442754 |
| effects of zika virus strain and aedes mosquito species on vector competence. | in the western hemisphere, zika virus is thought to be transmitted primarily by aedes aegypti mosquitoes. to determine the extent to which ae. albopictus mosquitoes from the united states are capable of transmitting zika virus and the influence of virus dose, virus strain, and mosquito species on vector competence, we evaluated multiple doses of representative zika virus strains in ae. aegypti and ae. albopictus mosquitoes. virus preparation (fresh vs. frozen) significantly affected virus infect ... | 2017 | 28430564 |
| competence of aedes aegypti, ae. albopictus, and culex quinquefasciatus mosquitoes as zika virus vectors, china. | in china, the prevention and control of zika virus disease has been a public health threat since the first imported case was reported in february 2016. to determine the vector competence of potential vector mosquito species, we experimentally infected aedes aegypti, ae. albopictus, and culex quinquefasciatus mosquitoes and determined infection rates, dissemination rates, and transmission rates. we found the highest vector competence for the imported zika virus in ae. aegypti mosquitoes, some sus ... | 2017 | 28430562 |
| evidence of zika virus rna fragments in aedes albopictus (diptera: culicidae) field-collected eggs from camaçari, bahia, brazil. | a major mosquito-borne viral disease outbreak caused by zika virus (zikv) occurred in bahia, brazil, in 2015, largely due to transmission by the mosquito, aedes aegypti (l.). detecting zikv in field samples of ae. aegypti has proven problematic in some locations, suggesting other mosquito species might be contributing to the spread of zikv. in this study, several (five) adult aedes albopictus (skuse) mosquitoes that emerged from a 2015 field collection of eggs from camaçari, bahia, brazil, were ... | 2017 | 28419254 |
| chemosensory responses to the repellent nepeta essential oil and its major component nepetalactone by aedes aegypti (diptera: culicidae), a vector of zika virus. | nepeta essential oil (neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. however, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito aedes aegypti (l.), an important vector of zika virus, were poorly understood. here we show that neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female ae. aegypti. a gustatory rece ... | 2017 | 28407077 |
| quantitative proteomic analysis of mosquito c6/36 cells reveals host proteins involved in zika virus infection. | zika virus (zikv) is an emerging arbovirus belonging to the genus flavivirus of the family flaviviridae during replication processes, flavivirus manipulates host cell systems to facilitate its replication, while the host cells activate antiviral responses. identification of host proteins involved in the flavivirus replication process may lead to the discovery of antiviral targets. the mosquitoes aedes aegypti and aedes albopictus are epidemiologically important vectors for zikv, and effective re ... | 2017 | 28404849 |
| laboratory evaluation of a novel lethal ovitrap for control of aedes aegypti. | aedes aegypti (l.) (diptera: culicidae) are known to flourish in a variety of natural and residential habitats and are competent vectors of at least 22 different arboviruses, including dengue, chikungunya, and zika. their global distribution, anthropophilic nature, and vector competency make them species of interest for control. a novel durable dual-action lethal ovitrap (ddalo) with combined larviciding and adulticiding effects, as well as a slow-release polymer (isobutyl methacrylate), was des ... | 2017 | 28968892 |
| characterization of the zika virus induced small rna response in aedes aegypti cells. | rna interference (rnai) controls arbovirus infections in mosquitoes. two different rnai pathways are involved in antiviral responses: the piwi-interacting rna (pirna) and exogenous short interfering rna (exo-sirna) pathways, which are characterized by the production of virus-derived small rnas of 25-29 and 21 nucleotides, respectively. the exo-sirna pathway is considered to be the key mosquito antiviral response mechanism. in aedes aegypti-derived cells, zika virus (zikv)-specific sirnas were pr ... | 2017 | 29040304 |
| patchy dna forms of the zika virus rna genome are generated following infection in mosquito cell cultures and in mosquitoes. | zika virus (zikv) is a mosquito-borne flavivirus and has historically been reported to cause mild symptomatic diseases during human infections. more recently, the explosion of microcephaly among infants born to zikv-infected women has made zikv a global public health concern. while zikv causes acute human diseases, infections of vector mosquitoes are basically non-pathogenic, allowing persistent infections and conferring lifelong ability to transmit the virus. recent studies have revealed that d ... | 2017 | 29039731 |
| lure-and-kill yeast interfering rna larvicides targeting neural genes in the human disease vector mosquito aedes aegypti. | new mosquito control strategies are vitally needed to address established arthropod-borne infectious diseases such as dengue and yellow fever and emerging diseases such as zika and chikungunya, all of which are transmitted by the disease vector mosquito aedes aegypti. in this investigation, saccharomyces cerevisiae (baker's yeast) was engineered to produce short hairpin rnas (shrnas) corresponding to the aedes aegypti orthologs of fasciculation and elongation protein zeta 2 (fez2) and leukocyte ... | 2017 | 29038510 |
| perturbed cholesterol and vesicular trafficking associated with dengue blocking in wolbachia-infected aedes aegypti cells. | wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control. to better understand the mechanisms of virus inhibition, we here perform proteomic quantification of the effects of wolbachia in aedes aegypti mosquito cells and midgut. perturbations are observed in vesicular trafficking, lipid metabolism and in the endoplasmic reticulum that could impact viral entry a ... | 2017 | 28904344 |
| minimum infectious dose for chikungunya virus in aedes aegypti and ae. albopictus mosquitoes. | understanding the ability of the chikungunya virus (chikv) to be transmitted by aedes vectors in the americas is critical for assessing epidemiological risk. one element that must be considered is the minimum infectious dose of virus that can lead to transmission following the extrinsic incubation period. this study aimed to determine the minimum infection rate for the two aedes species studied. the results revealed that doses as low as 3.9 log10 plaque-forming units per ml (pfu/ml) of an asian ... | 2017 | 28902278 |
| first detection of dengue and chikungunya viruses in natural populations of aedes aegypti in martinique during the 2013 - 2015 concomitant outbreak. | dengue and chikungunya viruses are transmitted by aedes mosquitoes. in martinique, an island of the french west indies, aedes aegypti is the suspected vector of both arboviruses; there is no aedes albopictus on the island. during the concomitant outbreak of 2013 - 2015, the authors collected wild a. aegypti populations, and for the first time, detected dengue and chikungunya viruses in field-collected females. this paper demonstrates the mosquito's role in transmission of both dengue and chikung ... | 2017 | 28902276 |
| highly effective broad spectrum chimeric larvicide that targets vector mosquitoes using a lipophilic protein. | two mosquitocidal bacteria, bacillus thuringiensis subsp. israelensis (bti) and lysinibacillus sphaericus (ls) are the active ingredients of commercial larvicides used widely to control vector mosquitoes. bti's efficacy is due to synergistic interactions among four proteins, cry4aa, cry4ba, cry11aa, and cyt1aa, whereas ls's activity is caused by bin, a heterodimer consisting of bina, the toxin, and binb, a midgut-binding protein. cyt1aa is lipophilic and synergizes bti cry proteins by increasing ... | 2017 | 28900215 |
| efficacy of blood sources and artificial blood feeding methods in rearing of aedes aegypti (diptera: culicidae) for sterile insect technique and incompatible insect technique approaches in sri lanka. | selection of the artificial membrane feeding technique and blood meal source has been recognized as key considerations in mass rearing of vectors. | 2017 | 28894749 |
| a natural hybrid of a bacillus thuringiensis cry2a toxin implicates domain i in specificity determination. | a pcr-rflp method was used to identify cry2a toxin genes in a collection of 300 strains of bacillus thuringiensis. from 81 genes identified, the vast majority appeared to be cry2aa or cry2ab, however three showed a different pattern and were subsequently cloned and sequenced. the gene cloned from strain hd395 was named cry2ba2. since the proteins encoded by the genes cloned from ls5115-3 and ds415 shared >95% sequence identity with existing toxins their genes were named cry2aa17 and cry2ab29 res ... | 2017 | 28888766 |
| isolation of a larvicidal compound from piper solmsianum c.dc. (piperaceae). | the aedes aegypti mosquito is one of the major vectors of arboviruses. these diseases have re-emerged and the insecticides used nowadays are toxic to mammals and environment and have only been effective in the short-term. in this context, natural products are an alternative. the genus piper has many active compounds against arthropods, including neolignans. the present study evaluated the larvicidal potential of the n-hexanic extract of piper solmsianum and eupomatenoid-6, identified by gc-ms an ... | 2017 | 28882070 |
| association between suspected zika virus disease during pregnancy and giving birth to a newborn with congenital microcephaly: a matched case-control study. | in early 2015, an outbreak of an acute exanthematous illness with dengue-like symptoms occurred in northeastern brazil. by the end of the same year, an unexpected increase in the number of cases of microcephaly was observed in the region. the microcephaly outbreak cause was unknown and rumors pointing to various potential causes arose. since we were unaware at the time if this scenario would attract the interest of the broader scientific community, due to the neglected regions associated and as ... | 2017 | 28877754 |
| microrna-277 targets insulin-like peptides 7 and 8 to control lipid metabolism and reproduction in aedes aegypti mosquitoes. | hematophagous female mosquitoes transmit numerous devastating human diseases, including malaria, dengue fever, zika virus, and others. because of their obligatory requirement of a vertebrate blood meal for reproduction, these mosquitoes need a lot of energy; therefore, understanding the molecular mechanisms linking metabolism and reproduction is of particular importance. lipids are the major energy store providing the fuel required for host seeking and reproduction. they are essential components ... | 2017 | 28874536 |
| updated reported distribution of aedes (stegomyia) aegypti and aedes (stegomyia) albopictus (diptera: culicidae) in the united states, 1995-2016. | aedes (stegomyia) aegypti (l.) and aedes (stegomyia) albopictus (skuse) are potential vectors of zika, dengue, and chikungunya viruses in the united states. a zika virus outbreak in florida in the summer of 2016, driven by ae. aegypti and resulting in > 200 locally acquired cases of human illness, underscored the need for up-to-date information on the geographic distribution of ae. aegypti and ae. albopictus in the united states. in early 2016, we conducted a survey and literature review to comp ... | 2017 | 28874014 |
| "we need people to collaborate together against this disease": a qualitative exploration of perceptions of dengue fever control in caregivers' of children under 5 years, in the peruvian amazon. | dengue fever presents a significant and growing burden of disease to endemic countries, where children are at particular risk. worldwide, no effective anti-viral treatment has been identified, thus vector control is key for disease prevention, particularly in peru where no vaccine is currently available. this qualitative study aimed to explore the perceptions of dengue control in caregivers' of children under 5 years in peru, to help direct future mosquito control programmes and strategy. | 2017 | 28873408 |
| fat body organ culture system in aedes aegypti, a vector of zika virus. | the insect fat body plays a central role in insect metabolism and nutrient storage, mirroring functions of the liver and fat tissue in vertebrates. insect fat body tissue is usually distributed throughout the insect body. however, it is often concentrated in the abdomen and attached to the abdominal body wall. the mosquito fat body is the sole source of yolk proteins, which are critical for egg production. therefore, the in vitro culture of mosquito fat body tissues represents an important syste ... | 2017 | 28872112 |
| evaluation of ecdysteroid antisera for a competitive enzyme immunoassay and extraction procedures for the measurement of mosquito ecdysteroids. | ecdysteroid hormones regulate several aspects of insect development and reproduction. the predominant ecdysteroids produced by insects including mosquitoes are ecdysone (e) and 20-hydroxyecdysone (20e). the ability to measure e and 20e titers is essential for many studies, but few sensitive, low cost options are currently available for doing so. to address this deficiency, we developed a new enzyme-linked immunoassay (eia). in the first part of the study, we compared the affinity of two new anti ... | 2017 | 28866256 |
| aedes aegypti saliva enhances chikungunya virus replication in human skin fibroblasts via inhibition of the type i interferon signaling pathway. | chikungunya virus (chikv) transmission occurs through the bite of an infected aedes mosquito which injects virus-containing saliva into the skin of the human host during blood feeding. in the present study, we have determined the effect of aedes aegypti saliva on chikv replication in human skin fibroblasts, a major cell type for viral entry, which mimics the events that occur during natural transmission. a significant increase in the expression of viral transcripts and infectious viral particles ... | 2017 | 28866137 |
| presence of a predator image in potential breeding sites and oviposition responses of a dengue vector. | in dengue vector control, attempts to minimize or replace the use of pesticides have mostly involved use of predators, but success has been severely impeded by difficulties associated with financial and environmental costs, predator mass production, and persistence in target habitats. visual deterrents have been used successfully to control animal pests, in some cases in an effort to replace pesticide use. despite evidence that visual signals are crucial in site choice for egg deposition by deng ... | 2017 | 28865898 |
| correction: insecticide resistance to permethrin and malathion and associated mechanisms in aedes aegypti mosquitoes from st. andrew jamaica. | [this corrects the article doi: 10.1371/journal.pone.0179673.]. | 2017 | 28859159 |
| effect of nozzle orientation on dispersion of aqualuer 20-20 sprayed by a truck-mounted ultra-low volume sprayer against caged aedes aegypti. | inconsistencies in efficacy of ultra-low volume (ulv) ground applications in the literature are linked to the lack of adjustments in sprayer parameters. to investigate the effect of nozzle orientation of a truck-mounted ulv sprayer on application efficacy, a study was conducted at st. johns county fairground, elkton, fl, during the summer of 2014. the efficacy was assessed by mortality of caged adult aedes aegypti, spray deposition, and droplet size spectrum up to 122 m from the spray line. aqua ... | 2017 | 28854107 |
| larvicidal and ovicidal activity of terminalia chebula retz. (family: combretaceae) medicinal plant extracts against anopheles stephensi, aedes aegypti and culex quinquefasciatus. | insect-borne diseases remain to this day a major source of illness and death worldwide. the resistance to chemical insecticides among mosquito species has been considered as a setback in vector control. mosquito control programs, botanical origin may have the potential to eliminate eggs and larvae. so, the larvicidal and ovicidal activities of crude benzene, hexane, ethyl acetate, chloroform and methanol extracts of terminalia chebula were assayed for their toxicity against three important vecto ... | 2017 | 28848262 |
| improving the built environment in urban areas to control aedes aegypti-borne diseases. | 2017 | 28804174 | |
| first report of coelomomyces santabrancae sp. nov. (blastocladiomycetes: blastocladiales) infecting mosquito larvae (diptera: culicidae) in central brazil. | a project from 2013 to 2017 sought to discover pathogenic fungi and oomycetes from dipteran species that are vectors of major diseases of humans and animals in central brazil and to begin evaluating the potential of these pathogens as potential biological control agents concentrated on mosquito larvae. some collecting sites proved to be especially productive for pathogens of naturally occurring mosquito species and for placements of healthy sentinel larvae of aedes aegypti in various sorts of co ... | 2017 | 28803981 |
| dinuclear silver(i)-n-heterocyclic carbene complexes: synthesis, characterization and larvicidal activity of bis-imidazolium dinuclear silver(i)-n-heterocyclic carbene complexes. | new synthesized bis-imidazolium salts that are linked by xylyl derivatives moiety, 1-4 was reacted with ag2o to facilitate the formation of dinuclear ag(i)-n-heterocyclic carbene (nhc) complexes, 5-8, respectively. all the synthesized ligand salts and complexes were characterized by 1h and 13c nmr, ftir spectroscopy and elemental analysis. molecular structures of compounds 3, 5, and 7 were elucidated by single crystal x-ray diffraction analyses. larvicidal studies against the aedes aegypti and c ... | 2017 | 28800547 |
| preparation of a nanoemulsion with carapa guianensis aublet (meliaceae) oil by a low-energy/solvent-free method and evaluation of its preliminary residual larvicidal activity. | andiroba (carapa guianensis) seeds are the source of an oil with a wide range of biological activities and ethnopharmacological uses. however, few studies have devoted attention to innovative formulations, including nanoemulsions. the present study aimed to obtain a colloidal system with the andiroba oil using a low-energy and organic-solvent-free method. moreover, the preliminary residual larvicidal activity of the nanoemulsion against aedes aegypti was evaluated. oleic and palmitic acids were ... | 2017 | 28798803 |
| mosquito species occurrence in association with landscape composition in green urban areas. | aedes aegypti prefers densely populated habitats, but has been shown to explore less anthropogenic environments. we investigated composition of the abundance of mosquitoes in forested areas and assessed relationships between species occurrences and different types of land use and land cover at three spatial scales (100m, 500m and 1000m). mosquitoes were collected from october 2012 to march 2013 using oviposition traps. we collected 4,179 mosquitoes in total including at least 10 species. aedes a ... | 2017 | 28793030 |
| insecticide resistance, associated mechanisms and fitness aspects in two brazilian stegomyia aegypti (= aedes aegypti) populations. | in brazil, insecticide resistance in stegomyia aegypti (= aedes aegypti) (diptera: culicidae) populations to pyrethroids and to the organophosphate (op) temephos is disseminated. currently, insect growth regulators (igrs) and the op malathion are employed against larvae and adults, respectively. bioassays with mosquitoes from two northeast municipalities, crato and aracaju, revealed, in both populations, susceptibility to igrs and malathion (rr95 ≤ 2.0), confirming the effectiveness of these co ... | 2017 | 28752548 |