Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| thermodynamics of tunnel formation upon substrate binding in a processive glycoside hydrolase. | glycoside hydrolases (ghs) catalyze the hydrolysis of glycosidic bonds and are key enzymes in carbohydrate metabolism. efficient degradation of recalcitrant polysaccharides such as chitin and cellulose is accomplished due to synergistic enzyme cocktails consisting of accessory enzymes and mixtures of ghs with different modes of action and active site topologies. the substrate binding sites of chitinases and cellulases often have surface exposed aromatic amino acids and a tunnel or cleft topology ... | 2017 | 28359644 |
| killing of serratia marcescens biofilms with chloramphenicol. | serratia marcescens is a gram-negative bacterium with proven resistance to multiple antibiotics and causative of catheter-associated infections. bacterial colonization of catheters mainly involves the formation of biofilm. the objectives of this study were to explore the susceptibility of s. marcescens biofilms to high doses of common antibiotics and non-antimicrobial agents. biofilms formed by a clinical isolate of s. marcescens were treated with ceftriaxone, kanamycin, gentamicin, and chloramp ... | 2017 | 28356113 |
| site-specific variation in gene expression from symbiodinium spp. associated with offshore and inshore porites astreoides in the lower florida keys is lost with bleaching and disease stress. | scleractinian coral are experiencing unprecedented rates of mortality due to increases in sea surface temperatures in response to global climate change. some coral species however, survive high temperature events due to a reduced susceptibility to bleaching. we investigated the relationship between bleaching susceptibility and expression of five metabolically related genes of symbiodinium spp. from the coral porites astreoides originating from an inshore and offshore reef in the florida keys. th ... | 2017 | 28355291 |
| polyclonal dissemination of kpc-2 in serratia marcescens, including a clone with epidemic behaviour in the nosocomial niche. | 2017 | 28336311 | |
| [serratia infections, should we think about primary immunodeficiencies?] | chronic granulomatous disease (cgd) is a primary immunodeficiency with an incidence of 1/200,000-250,000 live births. cgd affects mainly male patients, most of the mutations being x-linked, and autosomal recessive forms occur more frequently in communities with greater numbers of consanguineous marriages. cgd is characterized by sensitivity to recurrent and severe bacterial and fungal infections, with formation of granulomas due to the inability of phagocytes to generate reactive oxygen compound ... | 2017 | 28318195 |
| fulminant serratia marcescens panophthalmitis. | 2017 | 28317639 | |
| scleral buckle infection by serratia species. | we describe a rare case of scleral buckle (sb) infection with serratia species. a 48-year-old male with a history of retinal detachment repair with scleral buckling presented with redness, pain, and purulent discharge in the left eye for 4 days. conjunctival erosion with exposure of the sb and scleral thinning was noted. the sb was removed and sent for culture. blood and chocolate agar grew gram-negative rod-shaped bacillus identified as serratia marcescens. on the basis of the susceptibility te ... | 2017 | 28298863 |
| a novel expression system for lytic polysaccharide monooxygenases. | lytic polysaccharide monooxygenases (lpmos) are key enzymatic players of lignocellulosic biomass degradation processes. as such, they have been introduced in cellulolytic cocktails for more efficient and less expensive lignocellulose saccharification. the recombinant production of lpmos in bacteria for scientific investigations using vectors typically based on the t7 and lacuv5 promoters has been hampered by low yields. reasons for this have been catabolite repression when producing the proteins ... | 2017 | 28291518 |
| chorioamnionitis caused by serratia marcescens in a healthy pregnant woman with preterm premature rupture of membranes: a rare case report and review of the literature. | the incidence of chorioamnionitis varies widely. the highest incidence is reported in preterm deliveries. among preterm deliveries, chorioamnionitis usually occurs after preterm premature rupture of membranes (pprom). to date, only five cases of chorioamnionitis due to serratia marcescens were reported. here we present a case of a pregnant woman with chorioamnionitis due to serratia marcescens who delivered a premature neonate at 28 weeks and four days of gestation. we also conducted a review of ... | 2017 | 28283205 |
| draft genome sequence of a multidrug-resistant nosocomial serratia marcescens strain that persisted in a hospital in kemerovo, russian federation. | serratia marcescens is a frequent cause of health care-associated infections and has led to multiple outbreaks. here, we report the draft genome of a multidrug-resistant s. marcescens strain 189 which was isolated in 2012 as a predominant clone in a neonatal hospital in kemerovo. | 2017 | 28280035 |
| suppressor analysis of eepr mutant defects reveals coordinate regulation of secondary metabolites and serralysin biosynthesis by eepr and hexs. | the eepr transcription factor positively regulates secondary metabolites and tissue-damaging metalloproteases. to gain insight into mechanisms by which eepr regulates pigment and co-regulated factors, genetic suppressor analysis was performed. suppressor mutations that restored pigment to the non-pigmented ∆eepr mutant mapped to the hexs orf. mutation of hexs also restored haemolysis, swarming motility and protease production to the eepr mutant. hexs is a known direct and negative regulator of s ... | 2017 | 28270264 |
| crystal structure of mbp-pigg fusion protein and the essential function of pigg in the prodigiosin biosynthetic pathway in serratia marcescens fs14. | prodigiosin, a tripyrrole red pigment is synthesized by serratia and some other microbes through a bifurcated biosynthesis pathway; mbc (4-methoxy-2,2'-bipyrrole-5-carbaldehyde) and map (2-methyl-3-n-amyl-pyrrole) are synthesized separately and then condensed by pigc to form prodigiosin. pigi, pigg and piga have been shown to be involved in the first steps of mbc biosynthesis (proline incorporation). the crystal structure of pigg was resolved to elucidate its function and mechanism. pigg, an acy ... | 2017 | 28258005 |
| genome sequence of serratia marcescens msu97, a plant-associated bacterium that makes multiple antibiotics. | serratia marcescens msu97 was isolated from the guayana region of venezuela due to its ability to suppress plant-pathogenic oomycetes. here, we report the genome sequence of msu97, which produces various antibiotics, including the bacterial acetyl-coenzyme a (acetyl-coa) carboxylase inhibitor andrimid, the chlorinated macrolide oocydin a, and the red linear tripyrrole antibiotic prodigiosin. | 2017 | 28254993 |
| cultivable gut bacteria provide a pathway for adaptation of chrysolina herbacea to mentha aquatica volatiles. | a chemical cross-talk between plants and insects is required in order to achieve a successful co-adaptation. in response to herbivory, plants produce specific compounds, and feeding insects respond adequately7 to molecules produced by plants. here we show the role of the gut microbial community of the mint beetle chrysolina herbacea in the chemical cross-talk with mentha aquatica (or watermint). | 2017 | 28249605 |
| are genital ulcers always sexually transmitted? first report of scrotal ulcer caused by serratia marcescens infection. | 2017 | 28239854 | |
| scrotal ulcer due to serratia marcescens. | 2017 | 28196788 | |
| complete genome analysis of serratia marcescens rsc-14: a plant growth-promoting bacterium that alleviates cadmium stress in host plants. | serratia marcescens rsc-14 is a gram-negative bacterium that was previously isolated from the surface-sterilized roots of the cd-hyperaccumulator solanum nigrum. the strain stimulates plant growth and alleviates cd stress in host plants. to investigate the genetic basis for these traits, the complete genome of rsc-14 was obtained by single-molecule real-time sequencing. the genome of s. marcescens rsc-14 comprised a 5.12-mbp-long circular chromosome containing 4,593 predicted protein-coding gene ... | 2017 | 28187139 |
| lepidopteran species have a variety of defence strategies against bacterial infections. | the insect immune system has versatile ways of coping with microbial insults. currently, innate immune priming has been described in several invertebrates, and the first insights into its mechanistic basis have been described. here we studied infections with two different strains of serratia marcescens bacteria in two different lepidopteran hosts. the results reveal fundamental differences between the two hosts, a well-known model organism galleria mellonella and a non-model species arctia plant ... | 2017 | 28163013 |
| is there a role for serratia marcescens in male infertility: an experimental study? | establishment of a male balb/c mouse model to study the role of sperm impairing s. marcescens on mouse reproductive potential. the current study can add to use of reliable animal models to provide a noteworthy evidence for the microbial cause of infertility. | 2017 | 28161359 |
| serratia marcescens harboring sme-4 in brazil: a silent threat. | the intrinsic polymyxin resistance displayed by serratia marcescens makes the acquisition of carbapenemase encoding genes a worrisome event. this study report a sme-4-producing s. marcescens isolate causing septic shock in brazil. the insertion of novel resistance determinants and their consequent spread in our territory is noteworthy. | 2017 | 28159445 |
| organoselenium polymer inhibits biofilm formation in polypropylene contact lens case material. | contact lens-acquired bacterial infections are a serious problem. of the reported cases, inadequate cleaning of the lens case was the most common cause of lens contamination. organoselenium has been shown to inhibit bacterial attachment to different polymer materials. this study evaluates the ability of an organoselenium monomer, incorporated into the polymer of a polypropylene contact lens case coupon, to block the formation of biofilms in a lens case. | 2017 | 26974534 |
| long-chain 4-aminoquinolines as quorum sensing inhibitors in serratia marcescens and pseudomonas aeruginosa. | antibiotic resistance has become a serious global threat to public health; therefore, improved strategies and structurally novel antimicrobials are urgently needed to combat infectious diseases. here we report a new type of highly potent 4-aminoquinoline derivatives as quorum sensing inhibitors in serratia marcescens and pseudomonas aeruginosa, exhibiting weak bactericidal activities (minimum inhibitory concentration (mic) > 400 μm). through detailed structure-activity study, we have identified ... | 2017 | 28350449 |
| selenoprotein t is required for pathogenic bacteria avoidance in caenorhabditis elegans. | selenoprotein t (selenot) is an endoplasmatic reticulum (er)-associated redoxin that contains the amino acid selenocysteine (sec, u) within a cxxu motif within a thioredoxin-like fold. its precise function in multicellular organisms is not completely understood although it has been shown in mammals to be involved in ca(2+) homeostasis, antioxidant and neuroendocrine functions. here, we use the model organism c. elegans to address selenot function in a whole organism throughout its life cycle. c. ... | 2017 | 28347729 |
| oral polyphosphate suppresses bacterial collagenase production and prevents anastomotic leak due to serratia marcescens and pseudomonas aeruginosa. | the objective of this study was to determine the effect of polyphosphate on intestinal bacterial collagenase production and anastomotic leak in mice undergoing colon surgery. | 2017 | 28166091 |
| umbilical infections in foals: microbiological investigation and management. | this study aims to investigate the bacteria involved in equine omphalitis and their susceptibility to antimicrobial drugs, and consequently to provide guidelines concerning the most suitable treatment protocol in accordance with the clinical, ultrasound and laboratory findings. forty foals aged between one and 30 days were evaluated in the course of this investigation. an ultrasound examination of all umbilical remnants was carried out carefully in all foals; umbilical swabs were collected for b ... | 2017 | 28314783 |
| bombyx mori serpin6 regulates prophenoloxidase activity and the expression of antimicrobial proteins. | serpins are a family of serine protease inhibitors that are found widely in insects. they play an important role in insect physiological responses, such as innate immunity and development. in this study, we obtained the bombyx mori serpin6 (bmserpin6) sequence from national center for biotechnology information (ncbi) and the silkworm genome database (silkdb). reverse transcription pcr (rt-pcr) results showed that bmserpin6 was expressed highly in hemocytes, the midgut, and the fat body. after ch ... | 2017 | 28188867 |
| corneal ring infiltrates caused by serratia marcescens in a patient with human immunodeficiency virus. | to describe corneal ring infiltrates caused by serratia marcescens in a patient with human immunodeficiency virus (hiv-1) who wore contact lenses. | 2017 | 27721784 |
| the preparation and characterization of chitin and chitosan under large-scale submerged fermentation level using shrimp by-products as substrate. | the crustacean shells of crabs and shrimps produces quantities of by-products, leading to seriously environmental pollution and human health problems during industrial processing, yet they turned into high-value useful products, such as chitin and chitosan. to prepare them under large-scale submerged fermentation level, shrimp shell powders (ssps) was fermented by successive three-step fermentation of serratia marcescens b742, lactobacillus plantarum atcc 8014 and rhizopus japonicus m193 to extr ... | 2017 | 27965127 |
| serratia marcescens, morganella morganii, klebsiella oxytoca related peritonitis attacks in a patient on automated peritoneal dialysis: a case report. | 2017 | 28256286 | |
| protracted regional dissemination of gim-1-producing serratia marcescens in western germany. | the metallo-beta-lactamase gim-1 has been found in various bacterial host species nearly exclusively in western germany. however, not much is known about the epidemiology of gim-1-positive serratia marcescens here we report on a surprisingly protracted regional dissemination. in-hospital transmission was investigated by using conventional epidemiological tools to identify spatiotemporal links. strain typing was performed using pulsed-field gel electrophoresis (pfge) and whole-genome sequencing ( ... | 2017 | 27956426 |
| draft genome sequence of a ges-5-producing serratia marcescens isolated in southern brazil. | serratia marcescens is a gram-negative rod intrinsically resistant to polymyxins and usually associated with wound, respiratory and urinary tract infections. the whole genome of the first ges-5-producing s. marcescens isolated from a brazilian patient was sequenced using ion torrent pgm system. besides blages-5, we were able to identify genes encoding for other β-lactamases, for aminoglycoside modifying enzymes and for an efflux pump to tetracyclines. | 2017 | 27932081 |
| metastatic serratia endophthalmitis associated with extravasation injury in a preterm neonate. | the authors report a case of a preterm neonate who presented with lid edema, corneal edema, and an inflammatory membrane with whitish exudates in the pupillary area, suggestive of endophthalmitis. there was also a cutaneous ulcer with an eschar on the right wrist at the site of extravasation associated with previous intravenous catheter. cultures from the ulcer and vitreous samples both grew serratia marcescens with identical antibiotic sensitivity and resistance patterns. the ocular infection w ... | 2017 | 26622140 |
| kpc-producing serratia marcescens in a home-care patient from recife, brazil. | in this brief communication we describe the occurrence of a kpc-producing serratia marcescens isolate in a home-care patient from recife, brazil. the blakpc, blaspm, blaimp, blavim, blaoxa, blactx-m, blashv, blatem and blages genes were investigated by polymerase chain reaction (pcr) and dna sequencing. the isolate was positive for blakpc-2 and blatem-1 and was resistant to aztreonam, cefepime, cefotaxime, imipenem, meropenem, gentamicin, ciprofloxacin and cefazidime, and susceptible only to ami ... | 2017 | 26422164 |
| a pore-forming toxin enables serratia a nonlytic egress from host cells. | several pathogens co-opt host intracellular compartments to survive and replicate, and they thereafter disperse progeny to prosper in a new niche. little is known about strategies displayed by serratia marcescens to defeat immune responses and disseminate afterwards. upon invasion of nonphagocytic cells, serratia multiplies within autophagosome-like vacuoles. these serratia-containing vacuoles (secv) circumvent progression into acidic/degradative compartments, avoiding elimination. in this work, ... | 2017 | 27532510 |
| an antimicrobial protein of the riptortus pedestris salivary gland was cleaved by a virulence factor of serratia marcescens. | recently, our group demonstrated that the bean bug, riptortus pedestris, is a good experimental symbiosis model to study the molecular cross-talk between the host insect and the gut symbiont. the burkholderia symbiont is orally acquired by host nymphs from the environment in every generation. however, it is still unclear how riptortus specifically interacts with entomopathogens that are abundant in the environmental soil. in preliminary experiments, we observed that a potent entomopathogen, serr ... | 2017 | 27555079 |
| the antimicrobial spectrum of xeroform(®). | xeroform(®) is a petrolatum-based fine mesh gauze containing 3% bismuth tribromophenate. bismuth, similar to other metals, has antimicrobial properties. xeroform(®) has been used for decades in burn and plastic surgery as a donor site dressing and as a covering for wounds or partial thickness burns. despite this, the antimicrobial spectrum of xeroform(®) remains largely unknown. we examined the in-vitro efficacy of xeroform(®) against common burn pathogens using zone-of-inhibition methodology in ... | 2017 | 28641915 |
| association between pathogens from tracheal aspirate and oral biofilm of patients on mechanical ventilation. | the aim of this study was to detect possible associations between respiratory pathogens from tracheal aspirate and oral biofilm samples in intubated patients in an intensive care unit (icu), and to identify the most common respiratory pathogens in oral biofilm, particularly in patients that developed ventilator-associated pneumonia (vap). two oral biofilm samples were collected from the tongue of intubated patients (at admission and after 48 hours) and analyzed by culture with the antibiotic sen ... | 2017 | 28591237 |
| genomic and phenotypic characterisation of fluoroquinolone resistance mechanisms in enterobacteriaceae in durban, south africa. | resistance to fluoroquinolones (fq) is being increasingly reported and found to be mediated by efflux pumps, plasmid-mediated quinolone resistance genes (pmqr) and mutations in gyra, gyrb, parc and pare. however, studies reporting on fq resistance mechanisms (fqrm), particularly in africa, are focused mostly on salmonella. this study used a whole-genome-based approach to describe fqrm in forty-eight clinical enterobacteriaceae isolates comprising of klebsiella pneumoniae (n = 21), serratia marce ... | 2017 | 28636609 |
| allodemic distribution of plasmids co-harbouring blactx-m-15/aac(6')-ib-cr/qnrb in klebsiella pneumoniae is the main source of extended-spectrum β-lactamases in uruguay's paediatric hospital. | this study aimed to describe the characteristics of clinical isolates of extended-spectrum β-lactamase (esbl)-producing enterobacteria (epe) in uruguay's paediatric hospital. | 2017 | 28419869 |
| multi-effect of the water-soluble moringa oleifera lectin against serratia marcescens and bacillus sp.: antibacterial, antibiofilm and anti-adhesive properties. | to evaluate the antibiofilm potential of water-soluble moringa oleifera seed lectin (wsmol) on serratia marcescens and bacillus sp. | 2017 | 28792661 |
| innate immune system capabilities of the asian citrus psyllid, diaphorina citri. | citrus production worldwide is currently threatened by huanglongbing, or citrus greening disease. the associated pathogen, candidatus liberibacter asiaticus (clas), is transmitted by the asian citrus psyllid, diaphorina citri. annotation of the d. citri genome revealed a reduced innate immune system lacking a number of antimicrobial peptides and the imd pathway associated with defense against gram-negative bacteria. we characterized this apparent immune reduction in survival assays in which d. c ... | 2017 | 28624621 |
| biosynthesis of zno nanoparticles by a new pichia kudriavzevii yeast strain and evaluation of their antimicrobial and antioxidant activities. | the potential ability of a new yeast strain, pichia kudriavzevii, in the synthesis of zinc oxide nanoparticles (zno-nps) through a green method was explored in this study. the effect of reaction time (12, 24 and 36 h) on the structure of the resulting zno nanoparticles was investigated. from the xrd and tem results, the zno-nps with a hexagonal wurtzite structure and a particle crystal size of ~10-61 nm was formed at different reaction times. combing xrd, tem, and pl results, it was revealed tha ... | 2017 | 28538674 |
| insect pathogenic fungus interacts with the gut microbiota to accelerate mosquito mortality. | the insect gut microbiota plays crucial roles in modulating the interactions between the host and intestinal pathogens. unlike viruses, bacteria, and parasites, which need to be ingested to cause disease, entomopathogenic fungi infect insects through the cuticle and proliferate in the hemolymph. however, interactions between the gut microbiota and entomopathogenic fungi are unknown. here we show that the pathogenic fungus beauveria bassiana interacts with the gut microbiota to accelerate mosquit ... | 2017 | 28533370 |
| antibiotic resistance and virulence phenotypes of recent bacterial strains isolated from urinary tract infections in elderly patients with prostatic disease. | acute bacterial prostatitis is one of the frequent complications of urinary tract infection (uti). from the approximately 10% of men having prostatitis, 7% experience a bacterial prostatitis. the purpose of this study was to investigate the prevalence of uropathogens associated with utis in older patients with benign prostatic hyperplasia and to assess their susceptibility to commonly prescribed antibiotics as well as the relationships between microbial virulence and resistance features. uropath ... | 2017 | 28561794 |
| inactivation of the major hemolysin gene influences expression of the nonribosomal peptide synthetase gene swra in the insect pathogen serratia sp. strain scbi. | hemolysins are important virulence factors for many bacterial pathogens, including serratia marcescens the role of the major hemolysin gene in the insect pathogen serratia sp. scbi was investigated using both forward and reverse genetics approaches. introduction of the major hemolysin gene into escherichia coli resulted in a gain of both virulence and hemolytic activity. inactivation of this hemolysin in serratia sp. scbi resulted in loss of hemolysis, but did not attenuate insecticidal activity ... | 2017 | 28784817 |
| widespread fosfomycin resistance in gram-negative bacteria attributable to the chromosomal fosa gene. | fosfomycin is a decades-old antibiotic which is being revisited because of its perceived activity against many extensively drug-resistant gram-negative pathogens. fosa proteins are mn(2+) and k(+)-dependent glutathione s-transferases which confer fosfomycin resistance in gram-negative bacteria by conjugation of glutathione to the antibiotic. plasmid-borne fosa variants have been reported in fosfomycin-resistant escherichia coli strains. however, the prevalence and distribution of fosa in other g ... | 2017 | 28851843 |
| bacterial contamination in physical therapy departments in the state of kuwait. | [purpose] interferential therapy and electrical stimulation are electrophysical modalities commonly used in physical therapy departments to treat patients with musculoskeletal problems. these machines are applied directly to the patient's skin via a medium or electrodes, which can facilitate the transmission of microorganisms from one patient to another. the purpose of this study was to determine the extent of microorganism contamination in the machines sponges at physical therapy departments in ... | 2017 | 28626312 |
| evaluation of six phenotypic methods for the detection of carbapenemases in gram-negative bacteria with characterized resistance mechanisms. | we compared the performance of the modified hodge test (mht), triton hodge test (tht), carba np test (cnpt), simplified carba np test (cnpt-direct), blue-carba np test (bct), and carbapenem inactivation method (cim) for rapid and accurate carbapenemase detection. | 2017 | 28445009 |
| using phenotype microarrays in the assessment of the antibiotic susceptibility profile of bacteria isolated from wastewater in on-site treatment facilities. | the scope of the study was to apply phenotype biolog microarray (pm) technology to test the antibiotic sensitivity of the bacterial strains isolated from on-site wastewater treatment facilities. in the first step of the study, the percentage values of resistant bacteria from total heterotrophic bacteria growing on solid media supplemented with various antibiotics were determined. in the untreated wastewater, the average shares of kanamycin-, streptomycin-, and tetracycline-resistant bacteria wer ... | 2017 | 28451946 |
| the prevalence of antibiotic-resistant bacteria (arb) in waters of the lower ballona creek watershed, los angeles county, california. | screening for the prevalence of antibiotic-resistant bacteria (arb) was done at the ballona creek and wetlands, an urban-impacted wetland system in los angeles, california. the goals were (1) to assess the overall prevalence of arb, and (2) compare differences in arb abundance and the types of antibiotic resistance (ar) among the following sample types: lagoon water from del rey lagoon, urban runoff from ballona creek, and water from the ballona wetlands (tidal water flooding in from the adjacen ... | 2017 | 28488226 |
| antimicrobial properties of silver cations substituted to faujasite mineral. | a goal of our study was to find an alternative to nano-silver-based antimicrobial materials which would contain active silver immobilized in a solid matrix that prevents its migration into the surrounding environment. in this study, we investigated whether silver cations dispersed in an atomic form and trapped in an ion-exchanged zeolite show comparable antimicrobial activity to silver nanoparticles (nps). the biocidal active material was prepared from the sodium form of faujasite type zeolite i ... | 2017 | 28846614 |
| cyclohexene-fused 1,3-oxazines with selective antibacterial and antiparasitic action and low cytotoxic effects. | oxazine derivatives, a class of heterocyclic compounds, exhibit a variety of biological properties, such as anticonvulsant and antitumor activities. in this study, we evaluated the effect of two cyclohexene-fused 1,3-oxazines (cis‑1-benzyl-n-phenyl-1,4,4a,5,8,8a-hexahydro-3,1-benzoxazin-2-imine (1) and trans‑n-phenyl-1,4,4a,5,8,8a-hexahydro-3,1-benzoxazin-2-imine (2)) in cultures of bacillus cereus, enterococcus faecalis, escherichia coli, klebsiella pneumoniae, salmonella enterica, serratia mar ... | 2017 | 28755871 |
| incm plasmid r1215 is the source of chromosomally located regions containing multiple antibiotic resistance genes in the globally disseminated acinetobacter baumannii gc1 and gc2 clones. | clear similarities between antibiotic resistance islands in the chromosomes of extensively antibiotic-resistant isolates from the two dominant, globally distributed acinetobacter baumannii clones, gc1 and gc2, suggest a common origin. a close relative of the likely progenitor of both of these regions was found in r1215, a conjugative incm plasmid from a serratia marcescens strain isolated prior to 1980. the 37.8-kb resistance region in r1215 lies within the mucb gene and includes aacc1, aada1, a ... | 2017 | 27303751 |
| infectious disease exposures and outbreaks at a south african neonatal unit with review of neonatal outbreak epidemiology in africa. | hospitalized neonates are vulnerable to infection, with pathogen exposures occurring in utero, intrapartum, and postnatally. african neonatal units are at high risk of outbreaks owing to overcrowding, understaffing, and shared equipment. | 2017 | 28161461 |
| antimicrobial activity, ame resistance, and a-site binding studies of anthraquinone-neomycin conjugates. | the antibacterial effects of aminoglycosides are based on their association with the a-site of bacterial rrna and interference with the translational process in the bacterial cell, causing cell death. the clinical use of aminoglycosides is complicated by resistance and side effects, some of which arise from their interactions with the human mitochondrial 12s rrna and its deafness-associated mutations, c1494u and a1555g. we report a rapid assay that allows screening of aminoglycoside compounds to ... | 2017 | 28103015 |
| manual resuscitators in successive use in the same patient: reservoir of multi- and extensively resistant bacteria. | to determine the bacterial load on manual resuscitators (mrs), swab samples of mr connectors from a brazilian intensive care unit were collected at time zero, and after 24 and 48h use in the same patient. from 20 mrs, a total of 54 bacteria were isolated: six at t=0, 17 at t=24, and 31 at t=48. staphylococcus aureus, acinetobacter baumannii, serratia marcescens, and pseudomonas aeruginosa were the predominant isolates, and multidrug resistance was widespread in all species. greater awareness of ... | 2017 | 28012582 |
| bacteriological assessment of pneumonia caused by gram-negative bacteria in patients hospitalized in intensive care unit. | the article presents the results of 11-year study (2005-2015) of gram-negative bacteria responsible for pneumonia in 2033 mechanically ventilated patients hospitalized in intensive care unit. of 8796 biological samples, consisting mainly of bronchial aspirate (97.9 %), 2056 bacterial strains were isolated and subjected to identification. vitek 2 was used to determine drug susceptibility (classified according to the eucast criteria). esbl, mbl and kpc-producing strains were identified by means of ... | 2017 | 27739023 |
| bacterial coaggregation among the most commonly isolated bacteria from contact lens cases. | to examine the coaggregation and cohesion between the commonly isolated bacteria from contact lens cases. | 2017 | 28061510 |