Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| chemicals isolated from justicia adhatoda linn reduce fitness of the mosquito, aedes aegypti l. | extracts from justicia adhatoda l. (acanthaceae) strongly reduced the fitness of the mosquito, aedes aegypti linn. the methanolic extracts inhibited several enzymes responsible for protecting insects from oxidative and other damage, including glutathione-s-transferase, superoxide dismutase, cytochrome p450, and α- and β-esterases. they increased repellency (maximum repellency at 100 ppm) in host-seeking adult females using the "arm-in cage assay." histopathological examination showed the extract ... | 2017 | 28266058 |
| comparative luciferase assay for establishing reliable in vitro screening system of juvenile hormone agonists. | the cultured cell-based in vitro assay using the stringency of ligand-receptor interactions is typically useful for screening certain hormone agonists from among a very large number of molecules. however, ligands are frequently altered or modified through evolution; indeed, even in the same receptor orthologs, different ligand sensitivity profiles are considered to arise among species and/or taxa. such ligand transition has been observed in juvenile hormone (jh), one of the most important endocr ... | 2017 | 28261832 |
| blood feeding status, gonotrophic cycle and survivorship of aedes (stegomyia) aegypti (l.) (diptera: culicidae) caught in churches from merida, yucatan, mexico. | blood-feeding status, gonotrophic cycle, and survival rates of aedes (stegmyia) aegypti (l.) was investigated in catholic churches from merida, yucatan. female ae. aegypti were caught using backpack aspirator during 25 consecutive days in rainy (2015) and dry season (2016). blood-feeding status was determined by external examination of the abdomen and classified as unfed, fed, and gravid. daily changes in the parous-nulliparous ratio were recorded, and the gonotrophic cycle length was estimated ... | 2017 | 28258352 |
| insecticide susceptibility status and major detoxifying enzymes' activity in aedes albopictus (skuse), vector of dengue and chikungunya in northern part of west bengal, india. | mosquitoes belonging to aedes genus, aedes aegypti and aedes albopictus transmit many globally important arboviruses including dengue (denv) and chikungunya (chikv). vector control with the use of insecticide remains the suitable method of choice to stop the transmission of these diseases. however, vector control throughout the world is failing to achieve its target results because of the worldwide development of insecticide resistance in mosquitoes. to assess the insecticide susceptibility stat ... | 2017 | 28254583 |
| a mesh-duox pathway regulates homeostasis in the insect gut. | the metazoan gut harbours complex communities of commensal and symbiotic bacterial microorganisms. the quantity and quality of these microorganisms fluctuate dynamically in response to physiological changes. the mechanisms that hosts have developed to respond to and manage such dynamic changes and maintain homeostasis remain largely unknown. here, we identify a dual oxidase (duox)-regulating pathway that contributes to maintaining homeostasis in the gut of both aedes aegypti and drosophila melan ... | 2017 | 28248301 |
| allergenome characterization of the mosquito aedes aegypti. | saliva and muscle derived mosquito allergens have been purified and characterized. however, the complete set of allergens remains to be elucidated. in this study, we identified and characterized ige-binding proteins from the mosquito species a. aegypti. | 2017 | 28235135 |
| characterization of carbonic anhydrase 9 in the alimentary canal of aedes aegypti and its relationship to homologous mosquito carbonic anhydrases. | in the mosquito midgut, luminal ph regulation and cellular ion transport processes are important for the digestion of food and maintenance of cellular homeostasis. ph regulation in the mosquito gut is affected by the vectorial movement of the principal ions including bicarbonate/carbonate and protons. as in all metazoans, mosquitoes employ the product of aerobic metabolism carbon dioxide in its bicarbonate/carbonate form as one of the major buffers of cellular and extracellular ph. the conversio ... | 2017 | 28230813 |
| relish2 mediates bursicon homodimer-induced prophylactic immunity in the mosquito aedes aegypti. | bursicon is a neuropeptide hormone consisting of two cystine-knot proteins (burs α and burs β), responsible for cuticle tanning and other developmental processes in insects. recent studies show that each bursicon subunit forms homodimers that induce prophylactic immunity in drosophila melanogaster. here, we investigated the hypothesis that bursicon homodimers act in prophylactic immunity in insects, and possibly arthropods, generally, using the mosquito, aedes aegypti. we found that burs α and b ... | 2017 | 28225068 |
| transcriptome-wide microrna and target dynamics in the fat body during the gonadotrophic cycle of aedes aegypti. | the mosquito aedes aegypti is a major vector of numerous viral diseases, because it requires a blood meal to facilitate egg development. the fat body, a counterpart of mammalian liver and adipose tissues, is the metabolic center, playing a key role in reproduction. therefore, understanding of regulatory networks controlling its functions is critical, and the role of micrornas (mirnas) in the process is largely unknown. we aimed to explore mirna expression and potential targets in the female fat ... | 2017 | 28223504 |
| regulation of antimicrobial peptides in aedes aegypti aag2 cells. | antimicrobial peptides (amps) are an important group of immune effectors that play a role in combating microbial infections in invertebrates. most of the current information on the regulation of insect amps in microbial infection have been gained from drosophila, and their regulation in other insects are still not completely understood. here, we generated an amp induction profile in response to infections with some gram-negative, -positive bacteria, and fungi in aedes aegypti embryonic aag2 cell ... | 2017 | 28217557 |
| comparative analysis of mosquito (diptera: culicidae: aedes aegypti liston) responses to the insecticide temephos and plant derived essential oil derived from piper betle l. | resistance to treatments with temephos or plant derived oil, pb-cvo, between a field collected wild strain (ws) and a susceptible laboratory strain (ls) of ae. aegypti were measured. the temephos (0.1mg/l) showed the greatest percentage of mosquito mortality compared to pb-cvo (1.5mg/l) in ls ae. aegypti. however, ws ae. aegypti was not significantly affected by temephos (0.1mg/l) treatment compare to the pb-cvo (1.5mg/l). however, both strains (ls and ws) when treated with pb-cvo (1.5mg/l) disp ... | 2017 | 28213320 |
| household dengue prevention interventions, expenditures, and barriers to aedes aegypti control in machala, ecuador. | the aedes aegypti mosquito is an efficient vector for the transmission of zika, chikungunya, and dengue viruses, causing major epidemics and a significant social and economic burden throughout the tropics and subtropics. the primary means of preventing these diseases is household-level mosquito control. however, relatively little is known about the economic burden of ae. aegypti control in resource-limited communities. we surveyed residents from 40 households in a high-risk community at the urba ... | 2017 | 28212349 |
| development and characterization of recombinant virus generated from a new world zika virus infectious clone. | zika virus (zikv; family flaviviridae, genus flavivirus) is a rapidly expanding global pathogen that has been associated with severe clinical manifestations, including devastating neurological disease in infants. there are currently no molecular clones of a new world zikv available that lack significant attenuation, hindering progress toward understanding determinants of transmission and pathogenesis. here we report the development and characterization of a novel zikv reverse genetics system bas ... | 2017 | 27795432 |
| low circulation of zika virus, cambodia, 2007-2016. | we describe a retrospective study on circulation of zika virus in cambodia during 2007-2016 among patients with dengue-like symptoms and aedes aegypti mosquitoes. our findings suggest that zika virus in cambodia belongs to the asia genotype, is endemic, has low prevalence, and has had low-level impact on public health. | 2017 | 27875110 |
| sarniensine, a mesembrine-type alkaloid isolated from nerine sarniensis, an indigenous south african amaryllidaceae, with larvicidal and adulticidal activities against aedes aegypti. | a new mesembrine-type alkaloid, named sarniensine, was isolated together with tazettine, lycorine, the main alkaloid, and 3-epimacronine from nerine sarniensis, with the last two produced for the first time by this plant. this amaryllidaceae, which is indigenous of south africa, was investigated for its alkaloid content, because the organic extract of its bulbs showed strong larvicidal activity with an lc50 value of 0.008μgμl(-1) against first instar aedes aegypti larvae and with an ld50 value 4 ... | 2017 | 27864138 |
| understanding zika virus. | this article describes what pediatric healthcare professionals should know about zika virus (zikv). | 2017 | 27862959 |
| toxicity of ar-curcumene and epi-β-bisabolol from hedychium larsenii (zingiberaceae) essential oil on malaria, chikungunya and st. louis encephalitis mosquito vectors. | mosquitoes act as vectors of key pathogens and parasites. plant essential oils have been recognized as important sources of biopesticides, which do not induce resistance and have limited toxic effects on human health and non-target organisms. in this research, we evaluated the larvicidal and oviposition deterrence activity of hedychium larsenii essential oil (eo) and its major compounds ar-curcumene and epi-β-bisabolol. both molecules showed high toxicity against early third instars of anopheles ... | 2017 | 27918946 |
| zika virus-what the otolaryngologist should know: a review. | initially discovered in 1947, zika virus infection received little notoriety as a tropical disease until 2015 when an outbreak of microcephaly cases was reported in brazil. zika is a single-stranded rna arbovirus of the flaviviridae family. the primary source of infection in humans stems from aedes aegypti mosquito bites but can also occur through sexual, blood, and perinatal transmission. with expectations that 3 to 4 million people across the americas will be infected over the next year, the w ... | 2017 | 27892990 |
| an integrated approach for the assessment of the aedes aegypti and aedes albopictus global spatial distribution, and determination of the zones susceptible to the development of zika virus. | the zika virus, one of the new epidemic diseases, is reported to have affected millions of people in the past year. the suitable climate conditions of the areas where zika virus has been reported, especially in areas with a high population density, are the main cause of the current outbreak and spread of the disease. indeed, the suitable climatic conditions of certain territories constitute perfect breading nest for the propagation and outbreak of worldwide diseases. the main objective of this r ... | 2017 | 28111132 |
| experimental transmission of zika virus by mosquitoes from central europe. | mosquitoes collected in germany in 2016, including culex pipiens pipiens biotype pipiens, culex torrentium and aedes albopictus, as well as culex pipiens pipiens biotype molestus (in colony since 2011) were experimentally infected with zika virus (zikv) at 18 °c or 27 °c. none of the culex taxa showed vector competence for zikv. in contrast, aedes albopictus were susceptible for zikv but only at 27 °c, with transmission rates similar to an aedes aegypti laboratory colony tested in parallel. | 2017 | 28106528 |
| zika virus vector competency of mosquitoes, gulf coast, united states. | zika virus has recently spread throughout the americas. although aedes aegypti mosquitoes are considered the primary vector, culex quinquefasciatus and mosquitoes of other species may also be vectors. we tested cx. quinquefasciatus and ae. taeniorhynchus mosquitoes from the us gulf coast; both were refractory to infection and incapable of transmission. | 2017 | 28005002 |
| zika virus in asia. | zika virus (zikv) is an emerging mosquito-borne virus that was first isolated from a sentinel rhesus monkey in the zika forest in uganda in 1947. in asia, the virus was isolated in malaysia from aedes aegypti mosquitoes in 1966, and the first human infections were reported in 1977 in central java, indonesia. in this review, all reported cases of zikv infection in asia as of september 1, 2016 are summarized and some of the hypotheses that could currently explain the apparently low incidence of zi ... | 2017 | 27939768 |
| flavivirus transmission focusing on zika. | flaviviruses are among the most diverse viruses with over 85 species recognized. taxonomically, this genus is one of the 4 recognized genera within the family flaviviridae. most flaviviruses of human public health significance, for example, dengue, yellow fever and zika viruses, are arthropod-borne (arboviruses) and have two evolutionarily and ecologically distinct transmission cycles: a sylvatic transmission cycle, where the virus circulates between zoonotic vertebrate reservoir and amplificati ... | 2017 | 27936448 |
| spatial quantification of the world population potentially exposed to zika virus. | zika virus is an emerging flaviviridae virus, which has spread rapidly in the last few years. it has raised concern because it has been associated with fetus microcephaly when pregnant women are infected. the main vector is the mosquito aedes aegypti , distributed in tropical areas. | 2017 | 28338754 |
| boswellia ovalifoliolata (burseraceae) essential oil as an eco-friendly larvicide? toxicity against six mosquito vectors of public health importance, non-target mosquito fishes, backswimmers, and water bugs. | the use of synthetic pesticides to control vector populations is detrimental to human health and the environment and may lead to the development of resistant strains. plants can be alternative sources of safer compounds effective on mosquito vectors. in this study, the mosquito larvicidal activity of boswellia ovalifoliolata leaf essential oil (eo) was evaluated against anopheles stephensi, anopheles subpictus, aedes aegypti, aedes albopictus, culex quinquefasciatus, and culex tritaeniorhynchus. ... | 2017 | 28332087 |
| ascension island: a survey to assess the presence of zika virus vectors. | following concerns regarding the spread of zika virus, joint services health unit (cyprus) were tasked to carry out a mosquito survey on the ascension island, south atlantic. this was to determine if vectors of the virus such as aedes aegypti and aedes albopictus were introduced and established on the island. | 2017 | 28331047 |
| spatial-temporal analysis of dengue deaths: identifying social vulnerabilities. | currently, dengue fever, chikungunya fever, and zika virus represent serious public health issues in brazil, despite efforts to control the vector, the aedes aegypti mosquito. | 2017 | 28327810 |
| correction: laboratory strains of aedes aegypti are competent to brazilian zika virus. | [this corrects the article doi: 10.1371/journal.pone.0171951.]. | 2017 | 28288192 |
| variation in aedes aegypti mosquito competence for zika virus transmission. | to test whether zika virus has adapted for more efficient transmission by aedes aegypti mosquitoes, leading to recent urban outbreaks, we fed mosquitoes from brazil, the dominican republic, and the united states artificial blood meals containing 1 of 3 zika virus strains (senegal, cambodia, mexico) and monitored infection, dissemination, and virus in saliva. contrary to our hypothesis, cambodia and mexica strains were less infectious than the senegal strain. only mosquitoes from the dominican re ... | 2017 | 28287375 |
| <i>aedes aegypti</i> control through modernized, integrated vector management. | in the context of the ongoing, unprecedented zika virus outbreak in the americas, the world health organization has expressed its support for developing and up-scaling three novel approaches to controlling the aedes aegypti mosquito: the sterile insect technique (sit), the release of insects carrying dominant lethal genes (ridl) and the release of wolbachia-infected mosquitoes. whereas the former two approaches are temporary insect population suppression strategies, wolbachia infection is a self ... | 2017 | 28286698 |
| vertical transmission of zika virus by aedes aegypti and ae. albopictus mosquitoes. | to determine the potential role of vertical transmission in zika virus expansion, we evaluated larval pools of perorally infected aedes. aegypti and ae. albopictus adult female mosquitoes; ≈1/84 larvae tested were zika virus-positive; and rates varied among mosquito populations. thus, vertical transmission may play a role in zika virus spread and maintenance. | 2017 | 28277199 |
| zika in rio de janeiro: assessment of basic reproduction number and comparison with dengue outbreaks. | zika virus infection was declared a public health emergency of international concern in february 2016 in response to the outbreak in brazil and its suspected link with congenital anomalies. in this study, we use notification data and disease natural history parameters to estimate the basic reproduction number (r 0) of zika in rio de janeiro, brazil. we also obtain estimates of r 0 of dengue from time series of dengue cases in the outbreaks registered in 2002 and 2012 in the city, when denv-3 and ... | 2017 | 28240195 |
| combining contact tracing with targeted indoor residual spraying significantly reduces dengue transmission. | the widespread transmission of dengue viruses (denv), coupled with the alarming increase of birth defects and neurological disorders associated with zika virus, has put the world in dire need of more efficacious tools for aedes aegypti-borne disease mitigation. we quantitatively investigated the epidemiological value of location-based contact tracing (identifying potential out-of-home exposure locations by phone interviews) to infer transmission foci where high-quality insecticide applications c ... | 2017 | 28232955 |
| leaking containers: success and failure in controlling the mosquito aedes aegypti in brazil. | in 1958, the pan american health organization declared that brazil had successfully eradicated the mosquito aedes aegypti, responsible for the transmission of yellow fever, dengue fever, chikungunya, and zika virus. yet in 2016 the brazilian minister of health described the situation of dengue fever as "catastrophic." discussing the recent epidemic of zika virus, which amplified the crisis produced by the persistence of dengue fever, brazil's president declared in january 2016 that "we are in th ... | 2017 | 28207332 |
| does zika virus infection affect mosquito response to repellents? | the world health organization (who) recommends that people travelling to or living in areas with zika virus (zikv) outbreaks or epidemics adopt prophylactic measures to reduce or eliminate mosquito bites, including the use of insect repellents. it is, however, unknown whether repellents are effective against zikv-infected mosquitoes, in part because of the ethical concerns related to exposing a human subject's arm to infected mosquitoes in the standard arm-in-cage assay. we used a previously dev ... | 2017 | 28205633 |
| a cdna clone-launched platform for high-yield production of inactivated zika vaccine. | a purified inactivated vaccine (piv) using the zika virus (zikv) puerto rico strain prvabc59 showed efficacy in monkeys, and is currently in a phase i clinical trial. high-yield manufacture of this piv is essential for its development and vaccine access. here we report an infectious cdna clone-launched platform to maximize its yield. a single ns1 protein substitution (k265e) was identified to increase zikv replication on vero cells (a cell line approved for vaccine production) for both cambodian ... | 2017 | 28196656 |
| laboratory strains of aedes aegypti are competent to brazilian zika virus. | the zika virus outbreaks are unprecedented human threat in relation to congenital malformations and neurological/autoimmune complications. since this virus has high potential to spread in regions presenting the vectors, improvement in mosquito control is a top priority. thus, aedes aegypti laboratory strains will be fundamental to support studies in different research fields implicated on zika-mosquito interactions which are the basis for the development of innovative control methods. in this se ... | 2017 | 28187183 |
| predicting the potential role of non-human hosts in zika virus maintenance. | arboviruses are often maintained in complex cycles involving vertebrates such as mammals or birds and blood-feeding mosquitoes. however, the role of wildlife hosts in their emergence or re-emergence in human populations has received little attention. the recent emergence of zika virus in america, and previous occurrences of chikungunya and dengue, forces us to confront a potential new disease-emergence phenomenon. using a spatial data mining framework to identify potential biotic interactions, b ... | 2017 | 28180996 |
| larvicidal activity of blumea eriantha essential oil and its components against six mosquito species, including zika virus vectors: the promising potential of (4e,6z)-allo-ocimene, carvotanacetone and dodecyl acetate. | the effective and environmentally sustainable control of mosquitoes is a challenge of essential importance. this is due to the fact that some invasive mosquitoes, with special reference to the aedes genus, are particularly difficult to control, due to their high ecological plasticity. moreover, the indiscriminate overuse of synthetic insecticides resulted in undesirable effects on human health and non-target organisms, as well as resistance development in targeted vectors. here, the leaf essenti ... | 2017 | 28168560 |
| rplp1 and rplp2 are essential flavivirus host factors that promote early viral protein accumulation. | the flavivirus genus contains several arthropod-borne viruses that pose global health threats, including dengue viruses (denv), yellow fever virus (yfv), and zika virus (zikv). in order to understand how these viruses replicate in human cells, we previously conducted genome-scale rna interference screens to identify candidate host factors. in these screens, we identified ribosomal proteins rplp1 and rplp2 (rplp1/2) to be among the most crucial putative host factors required for denv and yfv infe ... | 2017 | 27974556 |
| diversity of yellow fever mosquito vectors in the atlantic forest of rio de janeiro, brazil. | environmental modifications caused by human activities have led to changes in mosquito vector populations, and sylvatic species have adapted to breeding in urban areas. | 2017 | 27384833 |
| does zika virus cause microcephaly - applying the bradford hill viewpoints. | zika virus has been documented since 1952, but been associated with mild, self-limiting disease. zika virus is classified as an arbovirus from a family of flaviviridae and primarily spread by aedes aegypti mosquitos. however, in a large outbreak in brazil in 2015, zika virus has been associated with microcephaly. | 2017 | 28357156 |
| host-virus interaction of zika virus in modulating disease pathogenesis. | the zika virus (zikv) is a newly emerging pathogen that has resulted in a worldwide epidemic. it primarily spreads either through infected aedes aegypti or aedes albopictus mosquitos leading to severe neurological disorders such as microcephaly and guillain-barré syndrome in susceptible individuals. the mode of zikv entry into specific cell types such as: epidermal keratinocytes, fibroblasts, immature dendritic cells (idcs), and stem-cell-derived human neural progenitors has been determined thro ... | 2017 | 28349242 |
| modelling wolbachia infection in a sex-structured mosquito population carrying west nile virus. | wolbachia is possibly the most studied reproductive parasite of arthropod species. it appears to be a promising candidate for biocontrol of some mosquito borne diseases. we begin by developing a sex-structured model for a wolbachia infected mosquito population. our model incorporates the key effects of wolbachia infection including cytoplasmic incompatibility and male killing. we also allow the possibility of reduced reproductive output, incomplete maternal transmission, and different mortality ... | 2017 | 28097419 |
| trypsin inhibitor from leucaena leucocephala seeds delays and disrupts the development of aedes aegypti, a multiple-disease vector. | nowadays, the aedes aegypti mosquito represents a serious public health issue in view of the large outbreaks of the arboviral diseases zika, dengue, chikungunya and yellow fever. this holometabolous insect has midgut digestive enzymes that are trypsin- and chymotrypsin-like proteins. protease inhibitors are able to bind to proteolytic enzymes and promote a blockage in digestion and nutrition, leading to death. thus, we investigated the effect of trypsin inhibitor of leucaena leucocephala (lti) s ... | 2017 | 27040615 |
| synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against aedes aegypti. | aedes aegypti is a major mosquito vector for the transmission of serious diseases, especially dengue and yellow fever. more than 1 billion people in developing countries are at risk. the widespread and continual use of pesticides can lead to resistant mosquitoes. in order to maintain mosquito control gains, it is critical to develop and evaluate novel bioactive molecules that differ in mode of action from currently used products. | 2017 | 27448764 |
| field comparisons of the gravid aedes trap (gat) and bg-sentinel trap for monitoring aedes albopictus (diptera: culicidae) populations and notes on indoor gat collections in vietnam. | we report on the use of the gravid aedes trap (gat) as a surveillance device for aedes albopictus (skuse) relative to the bg-sentinel (bgs) trap in field studies conducted in trenton, nj, and on hammond island, queensland, australia. a parallel study conducted in nha trang, vietnam, assessed the use of the gat as an indoor surveillance device as well as the use of canola oil as a noninsecticide killing agent. in trenton and hammond island, the gat collected fewer male (0.40 ± 0.12 and 0.43 ± 0.3 ... | 2017 | 27707983 |
| salinity responsive aquaporins in the anal papillae of the larval mosquito, aedes aegypti. | the larvae of the mosquito, aedes aegypti normally inhabit freshwater (fw) where they face dilution of body fluids by osmotic influx of water. in response, the physiological actions of the anal papillae result in ion uptake while the malpighian tubules and rectum work in concert to excrete excess water. in an apparent paradox, the anal papillae express aquaporins (aqps) and are sites of water permeability which, if aqps are expressed by the epithelium, apparently exaggerates the influx of water ... | 2017 | 27642095 |
| essential oils enhance the toxicity of permethrin against aedes aegypti and anopheles gambiae. | insecticide resistance and growing public concern over the safety and environmental impacts of some conventional insecticides have resulted in the need to discover alternative control tools. naturally occurring botanically-based compounds are of increased interest to aid in the management of mosquitoes. susceptible strains of aedes aegypti (linnaeus) (diptera: culicidae) and anopheles gambiae (meigen) (diptera: culicidae) were treated with permethrin, a common type-i synthetic pyrethroid, using ... | 2017 | 27800630 |
| how much does inbreeding reduce heterozygosity? empirical results from aedes aegypti. | deriving strains of mosquitoes with reduced genetic variation is useful, if not necessary, for many genetic studies. inbreeding is the standard way of achieving this. full-sib inbreeding the mosquito aedes aegypti for seven generations reduced heterozygosity to 72% of the initial heterozygosity in contrast to the expected 13%. this deviation from expectations is likely due to high frequencies of deleterious recessive alleles that, given the number of markers studied (27,674 single nucleotide pol ... | 2017 | 27799643 |
| the formulation of the essential oil of piper aduncum linnaeus (piperales: piperaceae) increases its efficacy as an insect repellent. | the essential oil (eo) of piper aduncum linnaeus, known as 'sireh lada' to locals malaysian, has the potential to be used as an alternative to synthetic insect repellents such as n,n-diethyl-meta-toluamide. however, the eo's efficacy as a repellent decreases after application due to the high volatility of its active ingredients. a number of studies have showed that optimizing the formulation of plant-based eos can improve their efficacy as repellents. the present study sought to evaluate the eff ... | 2017 | 27819201 |
| mosquito populations dynamics associated with climate variations. | mosquitoes are responsible for the transmission of numerous serious pathogens. members of the aedes and culex genera, which include many important vectors of mosquito-borne diseases, are highly invasive and adapted to man-made environments. they are spread around the world involuntarily by humans and are highly adapted to urbanized environments, where they are exposed to climate-related abundance drivers. we investigated culicidae fauna in two urban parks in the city of são paulo to analyze the ... | 2017 | 27810426 |
| repellency and larvicidal activity of essential oils from xylopia laevigata, xylopia frutescens, lippia pedunculosa, and their individual compounds against aedes aegypti linnaeus. | in order to find new alternatives for vector control and personal protection, we evaluated the larvicidal and repellent activity of essentials oils from plants found in the northeast of brazil against aedes aegypti linnaeus mosquitoes. the plants tested include xylopia laevigata, xylopia frutescens, and lippia pedunculosa and their major compounds, piperitenone oxide, and (r)-limonene. the essential oil of l. pedunculosa and its major volatile compounds were shown to be toxic for ae. aegypti lar ... | 2017 | 27844468 |
| dynamic expression of genes encoding subunits of inward rectifier potassium (kir) channels in the yellow fever mosquito aedes aegypti. | inward rectifier potassium (kir) channels play fundamental roles in neuromuscular, epithelial, and endocrine function in mammals. recent research in insects suggests that kir channels play critical roles in the development, immune function, and excretory physiology of fruit flies and/or mosquitoes. moreover, our group has demonstrated that mosquito kir channels may serve as valuable targets for the development of novel insecticides. here we characterize the molecular expression of 5 mrnas encodi ... | 2017 | 27836744 |
| establishment of aedes aegypti (l.) in mountainous regions in mexico: increasing number of population at risk of mosquito-borne disease and future climate conditions. | the study was conducted in the central region of veracruz mexico, in the metropolitan area of xalapa. it is a mountainous area where aedes aegypti (l.) is not currently endemic. an entomological survey was done along an elevation gradient using the ae. aegypti occurrences at different life cycle stages. seven sites were sampled and a total of 24 mosquito species were recorded: 9 species were found in urban areas, 18 in non-urban areas with remnant vegetation, and 3 occurred in both environments. ... | 2017 | 27863974 |
| aedes aegypti rhesus glycoproteins contribute to ammonia excretion by larval anal papillae. | in larval aedes aegypti, transcripts of the rhesus-like glycoproteins aerh50-1 and aerh50-2 have been detected in the anal papillae, sites of ammonia (nh3/nh4(+)) excretion; however, these putative ammonia transporters have not been previously localized or functionally characterized. in this study, we show that the aerh50s co-immunolocalize with apical v-type h(+)-atpase as well as with basal na(+)/k(+)-atpase in the epithelium of anal papillae. the double-stranded rna-mediated knockdown of aerh ... | 2017 | 27885043 |
| long-term spatio-temporal dynamics of the mosquito aedes aegypti in temperate argentina. | buenos aires city is located near the southern limit of the distribution of aedes aegypti (diptera: culicidae). this study aimed to assess long-term variations in the abundance of ae. aegypti in buenos aires in relation to changes in climatic conditions. ae. aegypti weekly oviposition activity was analyzed and compared through nine warm seasons from 1998 to 2014, with 200 ovitraps placed across the whole extension of the city. the temporal and spatial dynamics of abundances were compared among s ... | 2017 | 27876100 |
| expression of heat shock proteins (hsps) in aedes aegypti (l) and aedes albopictus (skuse) (diptera: culicidae) larvae in response to thermal stress. | climatic changes are responsible, to a certain extent for the occurrence and spread of arboviral pathogens world over. temperature is one of the important abiotic factors influencing the physiological processes of mosquitoes. several genes of heat shock protein (hsp) families are known to be expressed in mosquitoes, which aid in overcoming stress induced by elevated temperature. in order to understand expression of hsp family genes in the andaman population of aedes aegypti and aedes albopictus, ... | 2017 | 28024869 |
| mosquito repellent activity of volatile oils from selected aromatic plants. | essential oils from fresh leaves of four aromatic plants viz., ocimum sanctum, mentha piperita, eucalyptus globulus and plectranthus amboinicus were extracted by hydrodistillation. the test solutions were prepared as 20% essential oil in ethanol and positive control as 20% deet in ethanol. essential oil blend was prepared as 5% concentration. nulliparous, 3-5-day-old female adult aedes aegypti mosquitoes were used for repellency screening as per icmr protocol. the study showed that the repellenc ... | 2017 | 28013374 |
| influence of the length of storage on aedes aegypti (diptera: culicidae) egg viability. | aedes aegypti (l.) is one of the most important arboviral vectors worldwide. vector control is targeted at immature and adult stages; however, eggs are resistant to desiccation and may repopulate treated areas long after treatment ceases. we investigated the effect of age on ae. aegypti egg hatching rates using newly colonized populations (f2) from an arid region. we found a strongly negative association where older eggs had lower hatch rates. the capacity of eggs to survive for long periods of ... | 2017 | 28011737 |
| indoor resting behavior of aedes aegypti (diptera: culicidae) in acapulco, mexico. | the markedly anthropophilic and endophilic behaviors of aedes aegypti (l.) make it a very efficient vector of dengue, chikungunya, and zika viruses. although a large body of research has investigated the immature habitats and conditions for adult emergence, relatively few studies have focused on the indoor resting behavior and distribution of vectors within houses. we investigated the resting behavior of ae. aegypti indoors in 979 houses of the city of acapulco, mexico, by performing exhaustive ... | 2017 | 28011725 |
| toxicity and synergistic activities of chalcones against aedes aegypti (diptera: culicidae) and drosophila melanogaster (diptera: drosophilidae). | mosquito-borne illnesses are of great concern throughout the world, and chemical insecticides are commonly employed to decrease mosquito populations. however, the developmental insecticide pipeline for vector control has primarily been filled by repurposed agricultural products, and is hampered by their widespread use and insecticide resistance. the present study was performed in the search for new chemical insecticides or insecticide synergists. screening of 31 chalcone analogs was performed us ... | 2017 | 28011724 |
| exon-enriched libraries reveal large genic differences between aedes aegypti from senegal, west africa, and populations outside africa. | aedes aegypti is one of the most studied mosquito species, and the principal vector of several arboviruses pathogenic to humans. recently failure to oviposit, low fecundity, and poor egg-to-adult survival were observed when ae. aegypti from senegal (senaae) west africa were crossed with ae. aegypti (aaa) from outside of africa, and in senaae intercrosses. fluorescent in situ hybridization analyses indicated rearrangements on chromosome 1, and pericentric inversions on chromosomes 2 and 3. herein ... | 2017 | 28007834 |
| in vitro evaluation of the effect of botanical formulations used in the control of aedes aegypti l. (diptera: culicidae) on liver enzymes. | dengue fever is a viral disease transmitted by the aedes aegypti linn. (1792) (diptera: culicidae) mosquito, which is endemic in several regions of brazil. alternative methods for the control of the vector include botanical insecticides, which offer advantages such as lower environmental contamination levels and less likelihood of resistant populations. thus, in this study, the ability of botanical insecticide formulations to inhibit the activity of the liver enzymes serum cholinesterase and mal ... | 2017 | 28001215 |
| a biodegradable device for the controlled release of piper nigrum (piperaceae) standardized extract to control aedes aegypti (diptera, culicidae) larvae. | the significant increase in dengue, zika, and chikungunya and the resistance of the aedes aegypti mosquito to major insecticides emphasize the importance of studying alternatives to control this vector. the aim of this study was to develop a controlled-release device containing piper nigrum extract and to study its larvicidal activity against aedes aegypti. | 2017 | 28001214 |
| salinity alters snakeskin and mesh transcript abundance and permeability in midgut and malpighian tubules of larval mosquito, aedes aegypti. | this study examined the distribution and localization of the septate junction (sj) proteins snakeskin (ssk) and mesh in osmoregulatory organs of larval mosquito (aedes aegypti), as well as their response to altered environmental salt levels. ssk and mesh transcripts and immunoreactivity were detected in tissues of endodermal origin such as the midgut and malpighian tubules of a. aegypti larvae, but not in ectodermally derived hindgut and anal papillae. immunolocalization of ssk and mesh in the m ... | 2017 | 27988380 |
| diverse subcellular localizations of the insect cmp-sialic acid synthetases. | the occurrence and biological importance of sialic acid (sia) and its metabolic enzymes in insects have been studied using drosophila melanogaster. the most prominent feature of d. melanogaster cmp-sia synthetase (dmcss) is its golgi-localization, contrasted with nuclear localization of vertebrate csss. however, it remains unclear if the golgi-localization is common to other insect csss and why it happens. to answer these questions, aedes aegypti (mosquito) css (aacss) and tribolium castaneum (b ... | 2017 | 27986833 |
| long-lasting permethrin-impregnated clothing: protective efficacy against malaria in hyperendemic foci, and laundering, wearing, and weathering effects on residual bioactivity after worst-case use in the rain forests of french guiana. | personal protective measures against hematophagous vectors constitute the first line of defense against arthropod-borne diseases. however, guidelines for the standardized testing and licensing of insecticide-treated clothing are still lacking. the aim of this study was to analyze the preventive effect of long-lasting polymer-coated permethrin-impregnated clothing (ptbdu) against malaria after exposure to high-level disease transmission sites as well as the corresponding loss of permethrin and bi ... | 2017 | 27942961 |
| impact of terminalia chebula retz. against aedes aegypti l. and non-target aquatic predatory insects. | aedes aegypti linn is one of the most important mosquito species. the vectors are responsible for causing deadly diseases like dengue and dengue hemorrhagic fever. several chemical pesticides used to control these dengue vectors caused severe toxic significances on human health and other non-target beneficial insects. therefore the current investigation has been made to access the bio-efficacy of the crude seed extracts of t. chebula against the dengue vector ae. aegypti. the gc-ms analysis of c ... | 2017 | 27940415 |
| evaluation of larvicidal activity and ecotoxicity of linalool, methyl cinnamate and methyl cinnamate/linalool in combination against aedes aegypti. | the frequent use of synthetic pesticides to control aedes aegypti population can lead to environmental and/or human contamination and the emergence of resistant insects. linalool and methyl cinnamate are presented as an alternative to the synthetic pesticides, since they can exhibit larvicidal, repellent and/or insecticidal activity and are considered safe for use. the aim of this study was to evaluate the larvicidal activity of methyl cinnamate, linalool and methyl cinnamate/linalool in combina ... | 2017 | 28152405 |
| collective behavior quantification on human odor effects against female aedes aegypti mosquitoes-open source development. | classifying and quantifying mosquito activity includes a plethora of categories, ranging from measuring flight speeds, repellency, feeding rates, and specific behaviors such as home entry, swooping and resting, among others. entomologists have been progressing more toward using machine vision for efficiency for this endeavor. digital methods have been used to study the behavior of insects in labs, for instance via three-dimensional tracking with specialized cameras to observe the reaction of mos ... | 2017 | 28152031 |
| molecular characterization and expression analysis of p38 mapk gene and protein in aquatic midge, chironomus riparius (diptera: chironomidae), exposed to environmental contaminants. | p38 mitogen-activated protein kinase (mapk), an important signaling protein involved in various cellular processes, including stress responses, has been well characterized in model organisms. p38 has been identified in a number of insects, including the genus drosophila; however, its homologue in chironomus riparius has not yet been identified. in this study, we identified and characterized p38 mapk (crp38) gene in c. riparius using a transcriptome database that was previously generated 454 gs-f ... | 2017 | 28144697 |
| toxicological evaluation of essential oil from the leaves of croton argyrophyllus (euphorbiaceae) on aedes aegypti (diptera: culicidae) and mus musculus (rodentia: muridae). | plant-derived essential oils can be used as insecticides for vector control. however, to establish their safety, it is necessary to perform toxicological studies. herein, we evaluated the chemical composition and insecticidal activity of the essential oil from the leaves of croton argyrophyllus on the third- and fourth-instar larvae and adult aedes aegypti (l., 1762). we also evaluated the acute toxicity of the essential oil in adult female mus musculus the lethal concentration 50 (lc50) and 90 ... | 2017 | 28132021 |
| [aedes aegypti and aedes albopictus in bromeliads grown in the bauru municipal botanical gardens, são paulo, brazil]. | the aim of this study was to observe the occurrence of mosquito larvae, especially aedes aegypti and aedes albopictus, in the tanks and axillae of bromeliads at the bauru municipal botanical gardens, são paulo, brazil, highlighting the epidemiological implications for the use of these plants. the majority of the larvae belonged to mosquitos from genus culex, with only occasional findings of a. aegypti and a. albopictus. the use of screens for protection of the plants, exposure to sunlight, and l ... | 2017 | 28125119 |
| malpighian tubules as novel targets for mosquito control. | the malpighian tubules and hindgut are the renal excretory tissues of mosquitoes; they are essential to maintaining hemolymph water and solute homeostasis. moreover, they make important contributions to detoxifying metabolic wastes and xenobiotics in the hemolymph. we have focused on elucidating the molecular mechanisms of malpighian tubule function in adult female mosquitoes and developing chemical tools as prototypes for next-generation mosquitocides that would act via a novel mechanism of act ... | 2017 | 28125032 |
| new pesticidal diterpenoids from vellozia gigantea (velloziaceae), an endemic neotropical plant living in the endangered brazilian biome rupestrian grasslands. | vellozia gigantea is a rare, ancient, and endemic neotropical plant present in the brazilian rupestrian grasslands. the dichloromethane extract of v. gigantea adventitious roots was phytotoxic against lactuca sativa, agrostis stolonifera, and lemna paucicostata, and showed larvicidal activity against aedes aegypti. phytotoxicity bioassay-directed fractionation of the extract revealed one new isopimaradiene, 8(9),15-isopimaradien-1,3,7,11-tetraone, and three new cleistanthane diterpenoids, 7-oxo- ... | 2017 | 28117710 |
| histone-derived pirna biogenesis depends on the ping-pong partners piwi5 and ago3 in aedes aegypti. | the pirna pathway is of key importance in controlling transposable elements in most animal species. in the vector mosquito aedes aegypti, the presence of eight piwi proteins and the accumulation of viral pirnas upon arbovirus infection suggest additional functions of the pirna pathway beyond genome defense. to better understand the regulatory potential of this pathway, we analyzed in detail host-derived pirnas in a. aegypti aag2 cells. we show that a large repertoire of protein-coding genes and ... | 2017 | 28115625 |
| pyrethroid resistance in malaysian populations of dengue vector aedes aegypti is mediated by cyp9 family of cytochrome p450 genes. | dengue control and prevention rely heavily on insecticide-based interventions. however, insecticide resistance in the dengue vector aedes aegypti, threatens the continued effectiveness of these tools. the molecular basis of the resistance remains uncharacterised in many endemic countries including malaysia, preventing the design of evidence-based resistance management. here, we investigated the underlying molecular basis of multiple insecticide resistance in ae. aegypti populations across malays ... | 2017 | 28114328 |
| first report of stegomyia aegypti (= aedes aegypti) in mexico city, mexico. | stegomyia aegypti (= aedes aegypti) (diptera: culicidae) is a species of mosquito that is currently widespread in mexico. historically, the mosquito has been distributed across most tropical and subtropical areas lower than 1700 m a.s.l. currently, populations that are found at higher altitudes in regions with cold and dry climates suggest that these conditions do not limit the colonization and population growth of s. aegypti. during a survey of mosquitoes in september 2015, larvae of s. aegypti ... | 2017 | 28106260 |
| proteomics informed by transcriptomics for characterising active transposable elements and genome annotation in aedes aegypti. | aedes aegypti is a vector for the (re-)emerging human pathogens dengue, chikungunya, yellow fever and zika viruses. almost half of the ae. aegypti genome is comprised of transposable elements (tes). transposons have been linked to diverse cellular processes, including the establishment of viral persistence in insects, an essential step in the transmission of vector-borne viruses. however, up until now it has not been possible to study the overall proteome derived from an organism's mobile geneti ... | 2017 | 28103802 |
| mitigating diseases transmitted by aedes mosquitoes: a cluster-randomised trial of permethrin-impregnated school uniforms. | viral diseases transmitted via aedes mosquitoes are on the rise, such as zika, dengue, and chikungunya. novel tools to mitigate aedes mosquitoes-transmitted diseases are urgently needed. we tested whether commercially insecticide-impregnated school uniforms can reduce dengue incidence in school children. | 2017 | 28103255 |
| ecotoxicological effects of larvicide used in the control of aedes aegypti on nontarget organisms: redefining the use of pyriproxyfen. | the continued widespread use of larvicides in aedes aegypti control programs is still a necessary strategy, since there are no apparent efficient vaccines against arboviruses. however, chemical approaches may affect nontarget organisms and produce detrimental effects to environmental health. therefore, the aim of this study was to conduct toxicity testing for pyriproxyfen at different concentrations using daphnia magna and artemia salina as model organisms to evaluate the ecotoxicological parame ... | 2017 | 28095184 |
| excito-repellency of citrus hystrix dc leaf and peel essential oils against aedes aegypti and anopheles minimus (diptera: culicidae), vectors of human pathogens. | the essential oils of kaffir lime (citrus hystrix dc.) at four different concentrations (0.5, 1.0, 2.5, and 5.0% v/v) were studied for their repellency, excitation, and knockdown properties against laboratory strains of aedes aegypti (l.) and anopheles minimus theobald using an excito-repellency test system. both contact and noncontact escape responses to leaf- and peel-derived kaffir lime oils were observed. comparing unadjusted escape responses for an. minimus, leaf oil had strong combined irr ... | 2017 | 28082646 |
| toxicity and larvicidal activity of podophyllum-based lignans against aedes aegypti (diptera: culicidae). | aedes aegypti l. (diptera: culicidae) is a mosquito species that has adapted to urban environments and is the main vector of dengue viruses. because of the increasing incidence of dengue, a more environmentally acceptable insecticide needs to be found. natural products have been and continue to be an important source of leading compounds that can be modified in order to develop new drugs. the lignan family of natural products includes compounds with a diverse spectrum of biological activity. pod ... | 2017 | 28082643 |
| evaluation of clove oil, icaridin, and transfluthrin for spatial repellent effects in three tests systems against the aedes aegypti (diptera: culicidae). | one essential oil (clove oil), one skin repellent (icaridin), and one insecticide (transfluthrin) were tested for spatial repellent effects against non-blood-fed female aedes aegypti (l.) mosquitoes. the compounds were tested in acetone dilution series using a y-olfactometer, a double cage system, and a double room system. all compounds exhibited spatial repellent effects at certain concentrations. clove oil required relative high dosages to cause high effects (y-olfactometer 6 mg, double cage 6 ... | 2017 | 28082642 |
| egg hatching and survival of immature stages of aedes aegypti (diptera: culicidae) under natural temperature conditions during the cold season in buenos aires, argentina. | in temperate regions, the seasonal dynamics of aedes aegypti (l.) (diptera: culicidae) is mainly influenced by temperature. it is assumed that, during the winter season, the population remains as eggs and that the development and population growth of surviving eggs begin during the following spring. the aim of the current study was to assess egg hatching of ae. aegypti during the winter in buenos aires city (argentina), and analyze the survival of immature stages. the experiments consisted of im ... | 2017 | 28082637 |
| learning in mosquito larvae (aedes aegypti): habituation to a visual danger signal. | in spite of the mosquito aedes aegypti being a vector of several infectious diseases, a limited number of studies has been undertaken on learning in this species. moreover, larval stages have been neglected as model organisms, although they are active, aquatic and perform stereotyped behavioural responses, e.g. the escape response when disturbed. to study the learning abilities of mosquito larvae, we focused on habituation, a form of non-associative learning widely studied in vertebrates and inv ... | 2017 | 28077263 |
| rna interference for mosquito and mosquito-borne disease control. | rna interference (rnai) is a powerful tool to silence endogenous mosquito and mosquito-borne pathogen genes in vivo. as the number of studies utilizing rnai in basic research grows, so too does the arsenal of physiological targets that can be developed into products that interrupt mosquito life cycles and behaviors and, thereby, relieve the burden of mosquitoes on human health and well-being. as this technology becomes more viable for use in beneficial and pest insect management in agricultural ... | 2017 | 28067782 |
| the antiviral rnai response in vector and non-vector cells against orthobunyaviruses. | vector arthropods control arbovirus replication and spread through antiviral innate immune responses including rna interference (rnai) pathways. arbovirus infections have been shown to induce the exogenous small interfering rna (sirna) and piwi-interacting rna (pirna) pathways, but direct antiviral activity by these host responses in mosquito cells has only been demonstrated against a limited number of positive-strand rna arboviruses. for bunyaviruses in general, the relative contribution of sma ... | 2017 | 28060823 |
| bombyx mori and aedes aegypti form multi-functional immune complexes that integrate pattern recognition, melanization, coagulants, and hemocyte recruitment. | the innate immune system of insects responds to wounding and pathogens by mobilizing multiple pathways that provide both systemic and localized protection. key localized responses in hemolymph include melanization, coagulation, and hemocyte encapsulation, which synergistically seal wounds and envelop and destroy pathogens. to be effective, these pathways require a targeted deposition of their components to provide protection without compromising the host. extensive research has identified a larg ... | 2017 | 28199361 |
| meteorological variables and mosquito monitoring are good predictors for infestation trends of aedes aegypti, the vector of dengue, chikungunya and zika. | aedes aegypti is an important vector for arboviroses and widely distributed throughout the world. climatic factors can influence vector population dynamics and, consequently, disease transmission. the aim of this study was to characterize the temporal dynamics of an ae. aegypti population and dengue cases and to investigate the relationship between meteorological variables and mosquito infestation. | 2017 | 28193291 |
| prevalence of dengue and diversity of cultivable bacteria in vector aedes aegypti (l.) from two dengue endemic districts, kanchanpur and parsa of nepal. | dengue fever, an endemic arboviral disease, represents one of the major public health concerns in nepal. it is transmitted by bites of infected aedes aegypti and aedes albopictus, the former being primary vector. the bacterial community plays a significant role in biology of mosquitoes; however, the bacterial communities of primary vector a. aegypti remain unstudied in nepal. the study was designed to determine the rate of dengue seropositivity and to explore the bacterial diversity of a. aegypt ... | 2017 | 28193261 |
| leptolegnia chapmanii (straminipila: peronosporomycetes) as a future biorational tool for the control of aedes aegypti (l.). | the aim of the present review is to summarize the current knowledge about leptolegnia chapmanii as a pathogen of mosquito larvae. to this end, we present data on its identification, distribution, host range and effects on non-target organisms, effects of environmental factors, in vitro growth, release and persistence in anthropic environments, and effect combined with other insecticides. the data presented allow confirming its potential as a biocontrol agent. | 2017 | 28188766 |
| zika and chikungunya: mosquito-borne viruses in a changing world. | the reemergence and growing burden of mosquito-borne virus infections have incited public fear and growing research efforts to understand the mechanisms of infection-associated health outcomes and to provide better approaches for mosquito vector control. while efforts to develop therapeutics, vaccines, and novel genetic mosquito-control technologies are underway, many important underlying ecological questions remain that could significantly enhance our understanding and ability to predict and pr ... | 2017 | 28187236 |
| aedes aegypti larvicidal sesquiterpene alkaloids from maytenus oblongata. | four new sesquiterpene alkaloids (1-4) with a β-dihydroagrofuran skeleton and a new triterpenoid (5) were isolated from an ethyl acetate extract of maytenus oblongata stems. their structures were elucidated using 1d and 2d nmr spectroscopy as well as ms and ecd experiments. the m. oblongata stem etoac extract and the pure compounds isolated were tested for larvicidal activity against aedes aegypti under laboratory conditions, and compounds 2 and 3 were found to be active. | 2017 | 28186749 |
| single molecule rna sequencing uncovers trans-splicing and improves annotations in anopheles stephensi. | single molecule real-time (smrt) sequencing has recently been used to obtain full-length cdna sequences that improve genome annotation and reveal rna isoforms. here, we used one such method called isoform sequencing from pacific biosciences (pacbio) to sequence a cdna library from the asian malaria mosquito anopheles stephensi. more than 600 000 full-length cdnas, referred to as reads of insert, were identified. owing to the inherently high error rate of pacbio sequencing, we tested different ap ... | 2017 | 28181326 |
| xanthine dehydrogenase-1 silencing in aedes aegypti mosquitoes promotes a blood feeding-induced adulticidal activity. | aedesaegypti has 2 genes encoding xanthine dehydrogenase (xdh). we analyzed xdh1 and xdh2 gene expression by real-time quantitative pcr in tissues from sugar- and blood-fed females. differential xdh1 and xdh2 gene expression was observed in tissues dissected throughout a time course. we next exposed females to blood meals supplemented with allopurinol, a well-characterized xdh inhibitor. we also tested the effects of injecting double-stranded rna (dsrna) against xdh1, xdh2, or both. disruption o ... | 2017 | 28179423 |
| mosquitocidal activity and mode of action of the isoxazoline fluralaner. | mosquitoes, such as aedes aegypti and anopheles gambiae, are important vectors of human diseases. fluralaner, a recently introduced parasiticide, was evaluated as a mosquitocide in this study. on ae. aegypti and an. gambiae fourth-instar larvae, fluralaner had 24-h lc50 (lethal concentration for 50% mortality) values of 1.8 ppb and 0.4 ppb, respectively. following topical application to adult ae. aegypti, fluralaner toxicity reached a plateau in about 3 days, with 1- and 3-day ld50 (lethal dose ... | 2017 | 28178191 |
| sweet waste extract uptake by a mosquito vector: survival, biting, fecundity responses, and potential epidemiological significance. | in nature, adult mosquitoes typically utilize nectar as their main energy source, but they can switch to other as yet unidentified sugary fluids. contemporary lifestyles, with their associated unwillingness to consume leftovers and improper disposal of waste, have resulted in the disposal of huge amounts of waste into the environment. such refuse often contains unfinished food items, many of which contain sugar and some of which can collect water from rain and generate juices. despite evidence t ... | 2017 | 28174057 |
| reducing biting rates of aedes aegypti with metofluthrin: investigations in time and space. | indoor residual spraying is key to dengue control in cairns and other parts of northern queensland, australia, where aedes aegypti is prevalent, but the strategy faces challenges with regards to slow application time and, therefore, community coverage. a faster potential improvement might be the use of polyethylene netting impregnated with the volatile pyrethroid metofluthrin (sumione™). this formulation was assessed in rooms in three houses in cairns, australia. one emanator was placed in each ... | 2017 | 28173824 |