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essential oil of azorella cryptantha collected in two different locations from san juan province, argentina: chemical variability and anti-insect and antimicrobial activities.the essential oils (eos) of two populations of azorella cryptantha (clos) reiche, a native species from san juan province, were obtained by hydrodistillation in a clevenger-type apparatus and characterized by gc-fid and gc/ms analyses. the compounds identified amounted to 92.3 and 88.7% of the total oil composition for a. cryptantha from bauchaceta (ac-bau) and agua negra (ac-an), respectively. the eo composition for the two populations was similar, although with differences in the identity and ...201222899606
essential oil of azorella cryptantha collected in two different locations from san juan province, argentina: chemical variability and anti-insect and antimicrobial activities.the essential oils (eos) of two populations of azorella cryptantha (clos) reiche, a native species from san juan province, were obtained by hydrodistillation in a clevenger-type apparatus and characterized by gc-fid and gc/ms analyses. the compounds identified amounted to 92.3 and 88.7% of the total oil composition for a. cryptantha from bauchaceta (ac-bau) and agua negra (ac-an), respectively. the eo composition for the two populations was similar, although with differences in the identity and ...201222899606
epidemiology of dermatophytoses in crete, greece between 2004 and 2010.the present work was undertaken in order to study the epidemiology of dermatophytoses in the island of crete, greece, over a 7-year period (2004-2010) and to compare the results with those reported earlier from this region and from other parts of the world.201222648332
epidemiology of dermatophytoses in crete, greece between 2004 and 2010.the present work was undertaken in order to study the epidemiology of dermatophytoses in the island of crete, greece, over a 7-year period (2004-2010) and to compare the results with those reported earlier from this region and from other parts of the world.201222648332
dermatophyte infections mimicking other skin diseases: a 154-person case survey of tinea atypica in the district of cagliari (italy).although usually simple, the diagnosis of dermatophyte infection is sometimes neglected. an observational study has been realized to evaluate the role of corticosteroid exposure (tinea incognito) and of other primary characteristics of the dermatophytosis that from onset mimic other diseases and mislead an unexperienced physician.201222435428
dermatophyte infections mimicking other skin diseases: a 154-person case survey of tinea atypica in the district of cagliari (italy).although usually simple, the diagnosis of dermatophyte infection is sometimes neglected. an observational study has been realized to evaluate the role of corticosteroid exposure (tinea incognito) and of other primary characteristics of the dermatophytosis that from onset mimic other diseases and mislead an unexperienced physician.201222435428
formamido-diterpenes from the south china sea sponge acanthella cavernosa.seven new formamido-diterpenes, cavernenes a-d (1-4), kalihinenes e and f (5-6), and kalihipyran c (7), together with five known compounds (8-12), were isolated from the south china sea sponge acanthella cavernosa. structures were established using ir, hresims, 1d and 2d nmr, and single x-ray diffraction techniques. the isolated compounds were assessed for their cytotoxicity against a small panel of human cancer cell lines (hct-116, a549, hela, qgy-7701, and mda-mb-231) with ic(50) values in the ...201222851918
formamido-diterpenes from the south china sea sponge acanthella cavernosa.seven new formamido-diterpenes, cavernenes a-d (1-4), kalihinenes e and f (5-6), and kalihipyran c (7), together with five known compounds (8-12), were isolated from the south china sea sponge acanthella cavernosa. structures were established using ir, hresims, 1d and 2d nmr, and single x-ray diffraction techniques. the isolated compounds were assessed for their cytotoxicity against a small panel of human cancer cell lines (hct-116, a549, hela, qgy-7701, and mda-mb-231) with ic(50) values in the ...201222851918
bio-efficacy of dioscorea pentaphylla from midmid-western ghats, india.antibacterial and antifungal activity of crude extracts of medicinally important and traditionally used yam plant, dioscorea pentaphylla, from mid-western ghats was evaluated against 27 bacterial and 5 fungal clinical strains collected of the patients from infectious sources. the clinical strains belonging to their respective species showed concentration-dependent susceptibility toward crude petroleum ether extract, chloroform extract and methanol extract at 100 μg/100 μl. the extracts exhibited ...201222778504
bio-efficacy of dioscorea pentaphylla from midmid-western ghats, india.antibacterial and antifungal activity of crude extracts of medicinally important and traditionally used yam plant, dioscorea pentaphylla, from mid-western ghats was evaluated against 27 bacterial and 5 fungal clinical strains collected of the patients from infectious sources. the clinical strains belonging to their respective species showed concentration-dependent susceptibility toward crude petroleum ether extract, chloroform extract and methanol extract at 100 μg/100 μl. the extracts exhibited ...201222778504
antifungal activity of arctotis arctotoides (l.f.) o. hoffm. and gasteria bicolor haw. against opportunistic fungi associated with human immunodeficiency virus/acquired immunodeficiency syndrome.in south africa where many patients are immunocompromised as a result of the aids pandemic, opportunistic fungal infections such as candidiasis caused mainly by candida albicans are common. arctotis arctotoides and gasteria bicolor are two plants which are frequently and commonly used in traditional medicine in the treatment of hiv patients.201222701287
antifungal activity of arctotis arctotoides (l.f.) o. hoffm. and gasteria bicolor haw. against opportunistic fungi associated with human immunodeficiency virus/acquired immunodeficiency syndrome.in south africa where many patients are immunocompromised as a result of the aids pandemic, opportunistic fungal infections such as candidiasis caused mainly by candida albicans are common. arctotis arctotoides and gasteria bicolor are two plants which are frequently and commonly used in traditional medicine in the treatment of hiv patients.201222701287
prevalence of dermatomycosis in a brazilian tertiary care hospital.a total of 233 specimens obtained from suspected cases of dermatomycosis from 189 patients were examined for causative fungi from december 2009 to may 2010 in a tertiary care hospital in the city of belo horizonte, state of minas gerais, southeastern brazil. yeast and fungal isolates obtained from specimens were regarded as conclusive diagnosis of mycoses in 82 cases (35.19 %), with the exception of two patients with pityriasis versicolor (2.4 %), in which the diagnosis was made only by direct e ...201222936103
prevalence of dermatomycosis in a brazilian tertiary care hospital.a total of 233 specimens obtained from suspected cases of dermatomycosis from 189 patients were examined for causative fungi from december 2009 to may 2010 in a tertiary care hospital in the city of belo horizonte, state of minas gerais, southeastern brazil. yeast and fungal isolates obtained from specimens were regarded as conclusive diagnosis of mycoses in 82 cases (35.19 %), with the exception of two patients with pityriasis versicolor (2.4 %), in which the diagnosis was made only by direct e ...201222936103
semisynthesis and antimicrobial activity of novel guttiferone-a derivatives.six derivatives of guttiferone-a (lfqm-79, 80, 81, 82, 113 and 114) were synthesized and evaluated for their antimicrobial activity against the opportunistic or pathogenic fungi candida albicans (atcc 09548), candida glabrata (atcc 90030), candida krusei (atcc 6258), candida parapsilosis (atcc 69548), candida tropicalis (atcc 750), cryptococcus neoformans (atcc 90012), trichophyton tonsurans, microsporum gypseum and also against the opportunistic and pathogenic gram-positive bacteria staphylococ ...201222401914
semisynthesis and antimicrobial activity of novel guttiferone-a derivatives.six derivatives of guttiferone-a (lfqm-79, 80, 81, 82, 113 and 114) were synthesized and evaluated for their antimicrobial activity against the opportunistic or pathogenic fungi candida albicans (atcc 09548), candida glabrata (atcc 90030), candida krusei (atcc 6258), candida parapsilosis (atcc 69548), candida tropicalis (atcc 750), cryptococcus neoformans (atcc 90012), trichophyton tonsurans, microsporum gypseum and also against the opportunistic and pathogenic gram-positive bacteria staphylococ ...201222401914
antifungal property of quaternized chitosan and its derivatives.five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or n-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (quat188) as a quaternizing agent under basic condition. the degree of quaternization (dq) ranged between 28±2% and 90±2%. the antifungal activity was evaluated by using disc diffusion method, minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) methods against trichophyton rubrum (t. rubrum), trichophyton mentagrophyt ...201222100980
antifungal property of quaternized chitosan and its derivatives.five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or n-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (quat188) as a quaternizing agent under basic condition. the degree of quaternization (dq) ranged between 28±2% and 90±2%. the antifungal activity was evaluated by using disc diffusion method, minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) methods against trichophyton rubrum (t. rubrum), trichophyton mentagrophyt ...201222100980
antimicrobial activity of bioactive compounds and leaf extracts in jatropha tanjorensis.jatropha tanjorensis was investigated scientifically to generate evidence for the efficacies reported in traditional systems and the results are given here.201222884742
antimicrobial activity of bioactive compounds and leaf extracts in jatropha tanjorensis.jatropha tanjorensis was investigated scientifically to generate evidence for the efficacies reported in traditional systems and the results are given here.201222884742
isolation of microsporum gypseum in soil samples from different geographical regions of brazil, evaluation of the extracellular proteolytic enzymes activities (keratinase and elastase) and molecular sequencing of selected strains.a survey of microsporum gypseum was conducted in soil samples in different geographical regions of brazil. the isolation of dermatophyte from soil samples was performed by hair baiting technique and the species were identified by morphology studies. we analyzed 692 soil samples and the recuperating rate was 19.2%. the activities of keratinase and elastase were quantitatively performed in 138 samples. the sequencing of the its region of rdna was performed in representatives samples. m. gypseum is ...201224031904
isolation of microsporum gypseum in soil samples from different geographical regions of brazil, evaluation of the extracellular proteolytic enzymes activities (keratinase and elastase) and molecular sequencing of selected strains.a survey of microsporum gypseum was conducted in soil samples in different geographical regions of brazil. the isolation of dermatophyte from soil samples was performed by hair baiting technique and the species were identified by morphology studies. we analyzed 692 soil samples and the recuperating rate was 19.2%. the activities of keratinase and elastase were quantitatively performed in 138 samples. the sequencing of the its region of rdna was performed in representatives samples. m. gypseum is ...201224031904
prevalence of keratinophilic fungi in soils of st. kitts and nevis.information on the prevalence of keratinophilic fungi in west indies is scanty. occurrence of keratinophilic fungi in soils of st. kitts and nevis has not been investigated previously.201222505445
prevalence of keratinophilic fungi in soils of st. kitts and nevis.information on the prevalence of keratinophilic fungi in west indies is scanty. occurrence of keratinophilic fungi in soils of st. kitts and nevis has not been investigated previously.201222505445
antimicrobial and antioxidant activities of gentianella multicaulis collected on the andean slopes of san juan province, argentina.the infusion of the aerial parts of gentianella multicaulis (gillies ex griseb.) fabris (gentianaceae), locally known as 'nencia', is used in san juan province, argentina, as stomachic and as a bitter tonic against digestive and liver problems. the bioassay-guided isolation of g. multicaulis extracts and structural elucidation of the main compounds responsible for the antifungal and free radical scavenging activities were performed. the extracts had strong free radical scavenging effects in the ...201222486039
antimicrobial and antioxidant activities of gentianella multicaulis collected on the andean slopes of san juan province, argentina.the infusion of the aerial parts of gentianella multicaulis (gillies ex griseb.) fabris (gentianaceae), locally known as 'nencia', is used in san juan province, argentina, as stomachic and as a bitter tonic against digestive and liver problems. the bioassay-guided isolation of g. multicaulis extracts and structural elucidation of the main compounds responsible for the antifungal and free radical scavenging activities were performed. the extracts had strong free radical scavenging effects in the ...201222486039
pathology in practice. microsporum gypseum infection. 201222471823
pathology in practice. microsporum gypseum infection. 201222471823
kerion celsi due to arthroderma incurvatum infection in a sri lankan child: species identification and analysis of area-dependent genetic polymorphism.a three-year-old sri lankan boy residing in japan developed a nodule on his scalp after visiting sri lanka. two months later, the lesion increased in size to 22 × 19 mm(2), and was identified as an erythematous nodule with alopecia. direct examination of the infected hair shafts indicated fungal hyphae outside the shafts. the fungus was identified as microsporum gypseum following mycological examination. the sequence of the internal transcribed spacer 1 region of ribosomal rna gene (its1 rdna) e ...201222443310
kerion celsi due to arthroderma incurvatum infection in a sri lankan child: species identification and analysis of area-dependent genetic polymorphism.a three-year-old sri lankan boy residing in japan developed a nodule on his scalp after visiting sri lanka. two months later, the lesion increased in size to 22 × 19 mm(2), and was identified as an erythematous nodule with alopecia. direct examination of the infected hair shafts indicated fungal hyphae outside the shafts. the fungus was identified as microsporum gypseum following mycological examination. the sequence of the internal transcribed spacer 1 region of ribosomal rna gene (its1 rdna) e ...201222443310
keratinophilic fungi recovered from feathers of different species of birds in st kitts and nevis.the aim of the present study was to investigate the occurrence of keratinophilic fungi including dermatophytes on feathers of domestic and wild birds in the islands of st kitts and nevis.201224020233
keratinophilic fungi recovered from feathers of different species of birds in st kitts and nevis.the aim of the present study was to investigate the occurrence of keratinophilic fungi including dermatophytes on feathers of domestic and wild birds in the islands of st kitts and nevis.201224020233
isolation of fungi from housefly (musca domestica l.) at slaughter house and hospital in sanandaj, iran.houseflies have long been regarded as potential carriers of microorganisms especially fungi. since pathogenic microorganisms are widespread in the hospital environment, there is abundant opportunity for flies to become contaminated and in turn to contaminate the patient environment and residential regions. the aim of this study was to isolate and identify fungi from the slaughter house and the hospital environments.201223362625
isolation of fungi from housefly (musca domestica l.) at slaughter house and hospital in sanandaj, iran.houseflies have long been regarded as potential carriers of microorganisms especially fungi. since pathogenic microorganisms are widespread in the hospital environment, there is abundant opportunity for flies to become contaminated and in turn to contaminate the patient environment and residential regions. the aim of this study was to isolate and identify fungi from the slaughter house and the hospital environments.201223362625
tinea faciei by microsporum gypseum mimicking allergic reaction following cosmetic tattooing of the eyebrows.a 63-year-old healthy female patient presented with well defined itchy erythematous lesions on the area of her eyebrows. her eyebrows had been tattooed two months before her visit to us. the lesions had previously been treated by application of steroid ointment and anti-histamine and steroid tablets by mouth without success. we suspected the lesions to be contact dermatitis caused by some metal element contained in the dye used for tattooing. treatment was continued for two weeks, but the lesion ...201223257727
tinea faciei by microsporum gypseum mimicking allergic reaction following cosmetic tattooing of the eyebrows.a 63-year-old healthy female patient presented with well defined itchy erythematous lesions on the area of her eyebrows. her eyebrows had been tattooed two months before her visit to us. the lesions had previously been treated by application of steroid ointment and anti-histamine and steroid tablets by mouth without success. we suspected the lesions to be contact dermatitis caused by some metal element contained in the dye used for tattooing. treatment was continued for two weeks, but the lesion ...201223257727
dermatophytes from skin lesions of domestic animals in nsukka, enugu state, nigeria.dermatophytes are well-recognized cutaneous fungi with public health implications. in nigeria, several studies have been carried out on dermatophytosis in humans; however, data on dermatophytes in animals are lacking.201222913664
dermatophytes from skin lesions of domestic animals in nsukka, enugu state, nigeria.dermatophytes are well-recognized cutaneous fungi with public health implications. in nigeria, several studies have been carried out on dermatophytosis in humans; however, data on dermatophytes in animals are lacking.201222913664
disseminated dermatophytic pseudomycetoma caused by microsporum species.dermatophyte infection is almost exclusively a superficial cutaneous mycosis usually confined to the stratum corneum of nails and hairs of normal hosts. deep cutaneous and subcutaneous infections due to dermatophytes are exceedingly rare and usually limited to immunosuppressed individuals. these infections remain chronic and persist in spite of treatment.201223171014
disseminated dermatophytic pseudomycetoma caused by microsporum species.dermatophyte infection is almost exclusively a superficial cutaneous mycosis usually confined to the stratum corneum of nails and hairs of normal hosts. deep cutaneous and subcutaneous infections due to dermatophytes are exceedingly rare and usually limited to immunosuppressed individuals. these infections remain chronic and persist in spite of treatment.201223171014
comparative genome analysis of trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection.the major cause of athlete's foot is trichophyton rubrum, a dermatophyte or fungal pathogen of human skin. to facilitate molecular analyses of the dermatophytes, we sequenced t. rubrum and four related species, trichophyton tonsurans, trichophyton equinum, microsporum canis, and microsporum gypseum. these species differ in host range, mating, and disease progression. the dermatophyte genomes are highly colinear yet contain gene family expansions not found in other human-associated fungi. dermato ...201222951933
comparative genome analysis of trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection.the major cause of athlete's foot is trichophyton rubrum, a dermatophyte or fungal pathogen of human skin. to facilitate molecular analyses of the dermatophytes, we sequenced t. rubrum and four related species, trichophyton tonsurans, trichophyton equinum, microsporum canis, and microsporum gypseum. these species differ in host range, mating, and disease progression. the dermatophyte genomes are highly colinear yet contain gene family expansions not found in other human-associated fungi. dermato ...201222951933
an improved molecular diagnostic assay for canine and feline dermatophytosis.the few studies attempting to specifically characterize dermatophytes from hair samples of dogs and cats using pcr-based methodology relied on sequence-based analysis of selected genetic markers. the aim of the present investigation was to establish and evaluate a pcr-based approach employing genetic markers of nuclear dna for the specific detection of dermatophytes on such specimens. using 183 hair samples, we directly compared the test results of our one-step and nested-pcr assays with those b ...201322686247
an improved molecular diagnostic assay for canine and feline dermatophytosis.the few studies attempting to specifically characterize dermatophytes from hair samples of dogs and cats using pcr-based methodology relied on sequence-based analysis of selected genetic markers. the aim of the present investigation was to establish and evaluate a pcr-based approach employing genetic markers of nuclear dna for the specific detection of dermatophytes on such specimens. using 183 hair samples, we directly compared the test results of our one-step and nested-pcr assays with those b ...201322686247
epidemiological trends in zoophilic and geophilic fungi in iran.dermatophytes can be divided into geophilic (soil), zoophilic (animals) and anthropophilic (human) strains, depending on the source of the keratin. the predominant organisms vary within a given geographical region during different periods, which is influenced by a number of factors, such as population movements, socioeconomic circumstances and level of surveillance. thus, the incidence is very variable.201323095235
epidemiological trends in zoophilic and geophilic fungi in iran.dermatophytes can be divided into geophilic (soil), zoophilic (animals) and anthropophilic (human) strains, depending on the source of the keratin. the predominant organisms vary within a given geographical region during different periods, which is influenced by a number of factors, such as population movements, socioeconomic circumstances and level of surveillance. thus, the incidence is very variable.201323095235
microsatellite-primed pcr and random primer amplification polymorphic dna for the identification and epidemiology of dermatophytes.this study demonstrates the capacity of the one-step polymerase chain reaction (pcr) fingerprinting method using the microsatellite primers (gaca)4 or (gtg)5 (msp-pcr) to identify six of the most frequent dermatophyte species causing cutaneous mycosis. pcr with (gaca)4 was a suitable method to recognise microsporum canis, microsporum gypseum, trichophyton rubrum and trichophyton interdigitale among 82 argentinian clinical isolates, producing the most simple and reproducible band profiles. in con ...201323412735
microsatellite-primed pcr and random primer amplification polymorphic dna for the identification and epidemiology of dermatophytes.this study demonstrates the capacity of the one-step polymerase chain reaction (pcr) fingerprinting method using the microsatellite primers (gaca)4 or (gtg)5 (msp-pcr) to identify six of the most frequent dermatophyte species causing cutaneous mycosis. pcr with (gaca)4 was a suitable method to recognise microsporum canis, microsporum gypseum, trichophyton rubrum and trichophyton interdigitale among 82 argentinian clinical isolates, producing the most simple and reproducible band profiles. in con ...201323412735
antifungal activity of copaifera langsdorffii desf oleoresin against dermatophytes.dermatophytoses are mycoses that affect keratinized tissues in both humans and animals. the aim of this study was to investigate the antifungal activity of the oleoresin extracted from copaifera langsdorffii desf. against the strains microsporum canis atcc 32903, microsporum gypseum atcc 14683, trichophyton mentagrophytes atcc 11481 and trichophyton rubrum cct 5507. the antimicrobial activity was determined by minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) valu ...201324126374
antifungal activity of copaifera langsdorffii desf oleoresin against dermatophytes.dermatophytoses are mycoses that affect keratinized tissues in both humans and animals. the aim of this study was to investigate the antifungal activity of the oleoresin extracted from copaifera langsdorffii desf. against the strains microsporum canis atcc 32903, microsporum gypseum atcc 14683, trichophyton mentagrophytes atcc 11481 and trichophyton rubrum cct 5507. the antimicrobial activity was determined by minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) valu ...201324126374
white paint dot-like lesions of the scrotum: microsporum gypseum infection.a 29-year-old renal transplant patient taking mycophenolate mofetil 1 g b.i.d., cyclosporine 100 mg b.i.d. and prednisone 10 mg q.d. presented with white paint, dot-like incrustations on the skin of his right scrotum. a 10% potassium hydroxide preparation of scrapings from the lesions showed septate hyphae and microsporum gypseum was cultured. topical bifonazole 1% cream cleared the lesions within 2 weeks. at the 2-month follow up there was no relapse.201323043615
white paint dot-like lesions of the scrotum: microsporum gypseum infection.a 29-year-old renal transplant patient taking mycophenolate mofetil 1 g b.i.d., cyclosporine 100 mg b.i.d. and prednisone 10 mg q.d. presented with white paint, dot-like incrustations on the skin of his right scrotum. a 10% potassium hydroxide preparation of scrapings from the lesions showed septate hyphae and microsporum gypseum was cultured. topical bifonazole 1% cream cleared the lesions within 2 weeks. at the 2-month follow up there was no relapse.201323043615
antifungal compounds from the rhizome and roots of ferula hermonis.the antifungal activity of hexane, dichloromethane, methanol and aqueous extracts from the rhizome and root of ferula hermonis was assayed in vitro by the agar disk diffusion method against a panel of human opportunistic and pathogenic fungi. among them, the hexane and dichloromethane extracts showed the highest activity particularly against the dermatophytes microsporum gypseum and tricophyton mentagrophytes as well as the yeast candida lactis-condensi. activity-guided fractionation of both ext ...201322927102
antifungal compounds from the rhizome and roots of ferula hermonis.the antifungal activity of hexane, dichloromethane, methanol and aqueous extracts from the rhizome and root of ferula hermonis was assayed in vitro by the agar disk diffusion method against a panel of human opportunistic and pathogenic fungi. among them, the hexane and dichloromethane extracts showed the highest activity particularly against the dermatophytes microsporum gypseum and tricophyton mentagrophytes as well as the yeast candida lactis-condensi. activity-guided fractionation of both ext ...201322927102
isolation and molecular identification of keratinophilic fungi from public parks soil in shiraz, iran.keratinophilic fungi are an important group of fungi that live in soil. the aim of this study was to isolate and identify keratinophilic fungi from the soil of different parks in shiraz.201323956993
isolation and molecular identification of keratinophilic fungi from public parks soil in shiraz, iran.keratinophilic fungi are an important group of fungi that live in soil. the aim of this study was to isolate and identify keratinophilic fungi from the soil of different parks in shiraz.201323956993
microsporum gypseum dermatophytosis in a patient of acquired immunodeficiency syndrome: a rare case report.microsporum gypseum, a geophillic dermatophyte is rarely isolated from patients with acquired immunodeficiency syndrome. we report tinea corporis due to microsporum gypseum, an uncommon aetiological agent, in a patient with acquired immunodeficiency syndrome from our region. the clinical presentation resembled psoriasis characterised by atypical, scaly and hyperkeratotic lesions.201323883721
microsporum gypseum dermatophytosis in a patient of acquired immunodeficiency syndrome: a rare case report.microsporum gypseum, a geophillic dermatophyte is rarely isolated from patients with acquired immunodeficiency syndrome. we report tinea corporis due to microsporum gypseum, an uncommon aetiological agent, in a patient with acquired immunodeficiency syndrome from our region. the clinical presentation resembled psoriasis characterised by atypical, scaly and hyperkeratotic lesions.201323883721
canine and feline dermatophytosis due to microsporum gypseum: a retrospective study of clinical data and therapy outcome with griseofulvin.microsporum gypseum is a common inhabitant of the soil, occasionally responsible for human and animal ringworm. few reports describe the treatment of dermatologic diseases due to m. gypseum. the objective of this study was to evaluate retrospectively cases of m. gypseum infection in dogs and cats.201323827239
canine and feline dermatophytosis due to microsporum gypseum: a retrospective study of clinical data and therapy outcome with griseofulvin.microsporum gypseum is a common inhabitant of the soil, occasionally responsible for human and animal ringworm. few reports describe the treatment of dermatologic diseases due to m. gypseum. the objective of this study was to evaluate retrospectively cases of m. gypseum infection in dogs and cats.201323827239
successfully treated dermatomycosis in california sea lions (zalophus californianus).we describe clinical cases caused by microsporum gypseum in two subadult male california sea lions (zalophus californianus). dermatomycosis is uncommonly reported in pinnipeds, including this species. in these cases, skin lesions were multifocal to coalescing, involved all flippers, and were most pronounced on the ventral surfaces of flippers. they were well-demarcated, depigmented, and covered with crusts. the definitive diagnosis was obtained through microscopic examination and fungal culture ...201323805567
successfully treated dermatomycosis in california sea lions (zalophus californianus).we describe clinical cases caused by microsporum gypseum in two subadult male california sea lions (zalophus californianus). dermatomycosis is uncommonly reported in pinnipeds, including this species. in these cases, skin lesions were multifocal to coalescing, involved all flippers, and were most pronounced on the ventral surfaces of flippers. they were well-demarcated, depigmented, and covered with crusts. the definitive diagnosis was obtained through microscopic examination and fungal culture ...201323805567
microsporum fulvum, an ignored pathogenic dermatophyte: a new clinical isolation from iran.misidentifying with microsporum gypseum has for a long time been accounted for less prevalence of the geophilic species, microsporum fulvum in human dermatophytosis. we describe a new case of infection with the species in an iranian young man. direct examination of skin scrapings revealed a tinea corporis, and morphological study of the recovered isolate from the culture resulted in the identification of m. gypseum. however, pcr amplification of its1-5.8s rdna-its2 region and subsequent its-rflp ...201323700315
microsporum fulvum, an ignored pathogenic dermatophyte: a new clinical isolation from iran.misidentifying with microsporum gypseum has for a long time been accounted for less prevalence of the geophilic species, microsporum fulvum in human dermatophytosis. we describe a new case of infection with the species in an iranian young man. direct examination of skin scrapings revealed a tinea corporis, and morphological study of the recovered isolate from the culture resulted in the identification of m. gypseum. however, pcr amplification of its1-5.8s rdna-its2 region and subsequent its-rflp ...201323700315
kerion due to microsporum gypseum in a 1-month-old infant.microsporum gypseum is a rare cause of kerion in infancy. light microscopy, fluorescent microscopy and fungal culture of the infected hair aids in early and correct diagnosis. griseofulvin is the drug of choice for ectothrix fungi. we report a case of neonatal kerion caused by m. gypseum occurring at the age of 1 month, successfully treated with griseofulvin.201324778536
kerion due to microsporum gypseum in a 1-month-old infant.microsporum gypseum is a rare cause of kerion in infancy. light microscopy, fluorescent microscopy and fungal culture of the infected hair aids in early and correct diagnosis. griseofulvin is the drug of choice for ectothrix fungi. we report a case of neonatal kerion caused by m. gypseum occurring at the age of 1 month, successfully treated with griseofulvin.201324778536
screening of selected medicinal plants for in vitro antidermatophytic activity.different solvent extracts of leaves of achyranthes aspera, aegle marmelos, cleistanthus collinus, curcuma aromatica and strychnos nux-vomica were screened against dermatophytes viz., trichophyton mentagrophytes, t. rubrum, microsporum gypseum, m. canis and epidermophyton floccossum var. nigricans. the mean zones of inhibition were between 7.1 and 26.5mm. minimum inhibitory concentrations (mic) and minimum fungicidal concentrations (mfc) were from 7.81 to 500 and from 15.62 to 1000μg/ml respecti ...201324135649
screening of selected medicinal plants for in vitro antidermatophytic activity.different solvent extracts of leaves of achyranthes aspera, aegle marmelos, cleistanthus collinus, curcuma aromatica and strychnos nux-vomica were screened against dermatophytes viz., trichophyton mentagrophytes, t. rubrum, microsporum gypseum, m. canis and epidermophyton floccossum var. nigricans. the mean zones of inhibition were between 7.1 and 26.5mm. minimum inhibitory concentrations (mic) and minimum fungicidal concentrations (mfc) were from 7.81 to 500 and from 15.62 to 1000μg/ml respecti ...201324135649
successful use of silver impregnated hydrofiber dressing in the treatment of kerion celsi caused by microsporum gypseum.a method of treatment of tinea capitis is presented in a case of a 10-year-old boy who was referred to the pediatric surgical unit for the treatment of a skin lesion on the scalp, which had persisted for more than two months. the initial dermatologic examination led to the clinical diagnosis of inflammation of the scalp, while mycological analysis revealed an uncommon dermatophyte agent, microsporum gypseum, in the culture. the lesion was subsequently treated with local and oral antifungal agent ...201324476613
successful use of silver impregnated hydrofiber dressing in the treatment of kerion celsi caused by microsporum gypseum.a method of treatment of tinea capitis is presented in a case of a 10-year-old boy who was referred to the pediatric surgical unit for the treatment of a skin lesion on the scalp, which had persisted for more than two months. the initial dermatologic examination led to the clinical diagnosis of inflammation of the scalp, while mycological analysis revealed an uncommon dermatophyte agent, microsporum gypseum, in the culture. the lesion was subsequently treated with local and oral antifungal agent ...201324476613
urease gene of trichophyton rubrum var. raubitschekii.the recent description (in genbank) of a urease-encoding gene from trichophyton rubrum provides an opportunity to compare this species to the highly similar t. rubrum var. raubitschekii. therefore, the corresponding genomic dna was recovered from t. rubrum var. raubitschekii, and the sequence and expression were compared for this urease gene in urease-positive and -negative isolates of t. rubrum and t. rubrum var. raubitschekii. the sequence (2371 bp) of the t. rubrum var. raubitschekii urease g ...201323083471
antifungal efficacy of lasers against dermatophytes and yeasts in vitro.approximately 2-13% of the world population suffers from onychomycosis. recently, lasers have been introduced for treatment. however, no effect was found with in vitro laser irradiation of pathogens on agar plates. this study aimed to investigate the efficacy of laser irradiation against fungi using an alternative in vitro approach.201323957325
antifungal efficacy of lasers against dermatophytes and yeasts in vitro.approximately 2-13% of the world population suffers from onychomycosis. recently, lasers have been introduced for treatment. however, no effect was found with in vitro laser irradiation of pathogens on agar plates. this study aimed to investigate the efficacy of laser irradiation against fungi using an alternative in vitro approach.201323957325
investigation of chemical compounds, antioxidant and antimicrobial properties of teucrium arduini l. (lamiaceae).in this paper chemical composition of the essential oil (analysed by gc and gc-ms), the content of phenolic compounds (analysed by hplc), quantity of total phenols and total flavonoids (analysed by uv/vis spectrophotometer), antioxidant and antimicrobial activities of ethanolic extracts were investigated in endemic teucrium arduini l. in population of mt biokovo (croatia). the oil was characterized by a high concentration of sesquiterpene hydrocarbons (70.4%) of which β-caryophyllene (35.2%) and ...201323597042
investigation of chemical compounds, antioxidant and antimicrobial properties of teucrium arduini l. (lamiaceae).in this paper chemical composition of the essential oil (analysed by gc and gc-ms), the content of phenolic compounds (analysed by hplc), quantity of total phenols and total flavonoids (analysed by uv/vis spectrophotometer), antioxidant and antimicrobial activities of ethanolic extracts were investigated in endemic teucrium arduini l. in population of mt biokovo (croatia). the oil was characterized by a high concentration of sesquiterpene hydrocarbons (70.4%) of which β-caryophyllene (35.2%) and ...201323597042
anthraquinone profile, antioxidant and antimicrobial activity of bark extracts of rhamnus alaternus, r. fallax, r. intermedia and r. pumila.the quantity of phenols, as well as antioxidant and antimicrobial activities, were investigated in bark of rhamnus alaternus l., r. fallax boiss., r. intermedia steud. et hochst., and r. pumila turra from natural stands in croatia. the most abundant anthraquinones in the investigated extracts were chrysophanol in r. alaternus (3.14 mg/g), emodin in r. pumila (0.339 mg/g), and physcion in r. fallax (2.70 mg/g) and r. intermedia (0.285 mg/g). the species exhibiting the highest antioxidant activity ...201323122067
anthraquinone profile, antioxidant and antimicrobial activity of bark extracts of rhamnus alaternus, r. fallax, r. intermedia and r. pumila.the quantity of phenols, as well as antioxidant and antimicrobial activities, were investigated in bark of rhamnus alaternus l., r. fallax boiss., r. intermedia steud. et hochst., and r. pumila turra from natural stands in croatia. the most abundant anthraquinones in the investigated extracts were chrysophanol in r. alaternus (3.14 mg/g), emodin in r. pumila (0.339 mg/g), and physcion in r. fallax (2.70 mg/g) and r. intermedia (0.285 mg/g). the species exhibiting the highest antioxidant activity ...201323122067
isolation of the volatile fraction from apium graveolens l. (apiaceae) by supercritical carbon dioxide extraction and hydrodistillation: chemical composition and antifungal activity.apium graveolens l. (wild celery), belonging to the family of apiaceae, is a scaposus hemicryptophyte. instead, the cultivate plant is an annual or biennial herb widely used as a spice and seasoning in food. a broad range of biological activities have been attributed to a. graveolens. these include antimicrobial activity, larvicidal activity, hepatoprotective activity, nematicidal and mosquito repellent potential and antihyperlipidaemic properties.in this study, the authors compare the compositi ...201322974401
isolation of the volatile fraction from apium graveolens l. (apiaceae) by supercritical carbon dioxide extraction and hydrodistillation: chemical composition and antifungal activity.apium graveolens l. (wild celery), belonging to the family of apiaceae, is a scaposus hemicryptophyte. instead, the cultivate plant is an annual or biennial herb widely used as a spice and seasoning in food. a broad range of biological activities have been attributed to a. graveolens. these include antimicrobial activity, larvicidal activity, hepatoprotective activity, nematicidal and mosquito repellent potential and antihyperlipidaemic properties.in this study, the authors compare the compositi ...201322974401
czech ethanol-free propolis extract displays inhibitory activity against a broad spectrum of bacterial and fungal pathogens.propolis acts primarily as a biocide against invasive bacteria and fungi in the hive, suggesting its potential for industrial applications. in food application, propolis is considered as a chemical preservative in meat products, extending shelf life of frozen meat and other food. the mechanism of action is still unclear due to the synergy of multiple compounds contained in propolis and due to parallel targeting of multiple pathways within each affected organism. here, we examined the antimicrobi ...201323915150
czech ethanol-free propolis extract displays inhibitory activity against a broad spectrum of bacterial and fungal pathogens.propolis acts primarily as a biocide against invasive bacteria and fungi in the hive, suggesting its potential for industrial applications. in food application, propolis is considered as a chemical preservative in meat products, extending shelf life of frozen meat and other food. the mechanism of action is still unclear due to the synergy of multiple compounds contained in propolis and due to parallel targeting of multiple pathways within each affected organism. here, we examined the antimicrobi ...201323915150
biological activities of selected basidiomycetes from yemen.in a previous paper we demonstrated the results of biological screening of yemeni basidiomycetes. the present study was aimed to investigate the antimicrobial and the antioxidant activity of further basidiomycetes collected in yemen. dichloromethane, methanol and aqueous extracts of the fruiting bodies of 25 species were screened in vitro for their antibacterial activities against three gram-positive bacteria (staphyloccocus aureus, bacillus subtilis, micrococcus flavus) and two gram-negative ba ...201323556343
biological activities of selected basidiomycetes from yemen.in a previous paper we demonstrated the results of biological screening of yemeni basidiomycetes. the present study was aimed to investigate the antimicrobial and the antioxidant activity of further basidiomycetes collected in yemen. dichloromethane, methanol and aqueous extracts of the fruiting bodies of 25 species were screened in vitro for their antibacterial activities against three gram-positive bacteria (staphyloccocus aureus, bacillus subtilis, micrococcus flavus) and two gram-negative ba ...201323556343
hippolachnin a, a new antifungal polyketide from the south china sea sponge hippospongia lachne.hippolachnin a (1), a polyketide possessing an unprecedented carbon skeleton with a four-membered ring, was isolated from the south china sea sponge hippospongia lachne. the structure was elucidated using ms and nmr spectroscopic analyses, and the absolute configuration was determined using a calculated ecd method. hippolachnin a demonstrated potent antifungal activity against three pathogenic fungi, cryptococcus neoformans, trichophyton rubrum, and microsporum gypseum, with a mic value of 0.41 ...201323829334
hippolachnin a, a new antifungal polyketide from the south china sea sponge hippospongia lachne.hippolachnin a (1), a polyketide possessing an unprecedented carbon skeleton with a four-membered ring, was isolated from the south china sea sponge hippospongia lachne. the structure was elucidated using ms and nmr spectroscopic analyses, and the absolute configuration was determined using a calculated ecd method. hippolachnin a demonstrated potent antifungal activity against three pathogenic fungi, cryptococcus neoformans, trichophyton rubrum, and microsporum gypseum, with a mic value of 0.41 ...201323829334
synthesis, characterization, and antimicrobial evaluation of some new hydrazinecarbothioamide, 1,2,4-triazole and 1,3,4-thiadiazole derivatives.in this work, we reported the synthesis and evaluation of antibacterial and antifungal activities of three new compound series obtained from 6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazole-3-acetic acid hydrazide: 2-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]acetyl}-n-alkyl/arylhydrazinecarbothioamides (2a-d), 4-alkyl/aryl-2,4-dihydro-5-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]methyl}-3h-1,2,4-triazole-3-thiones (3a-n), and 2-alkyl/arylamino-5-{[6-(phenyl/4-chlorophenyl)i ...201322845330
synthesis, characterization, and antimicrobial evaluation of some new hydrazinecarbothioamide, 1,2,4-triazole and 1,3,4-thiadiazole derivatives.in this work, we reported the synthesis and evaluation of antibacterial and antifungal activities of three new compound series obtained from 6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazole-3-acetic acid hydrazide: 2-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]acetyl}-n-alkyl/arylhydrazinecarbothioamides (2a-d), 4-alkyl/aryl-2,4-dihydro-5-{[6-(phenyl/4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl]methyl}-3h-1,2,4-triazole-3-thiones (3a-n), and 2-alkyl/arylamino-5-{[6-(phenyl/4-chlorophenyl)i ...201322845330
efficacy of some synthesized thiazoles against dermatophytes.twelve thiazoles and their fused derivatives were tested for their antimicrobial activity against trichophyton rubrum, t. terrestre, epidermophyton floccosum, and microsporum gypseum. most of the synthesized compounds were inhibitory to the tested fungi. the most effective compound was 5-(4-ethoxybenzylidene-4,5-dihydro-4-oxothiazol-2-yl)-n,3-diphenylbut-2-namide (3c) followed by 2-(4-oxo-4,5-dihydrothiazol-2-yl)-3-phenyl-but-2-enoic acid-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-amide ( ...201324129248
efficacy of some synthesized thiazoles against dermatophytes.twelve thiazoles and their fused derivatives were tested for their antimicrobial activity against trichophyton rubrum, t. terrestre, epidermophyton floccosum, and microsporum gypseum. most of the synthesized compounds were inhibitory to the tested fungi. the most effective compound was 5-(4-ethoxybenzylidene-4,5-dihydro-4-oxothiazol-2-yl)-n,3-diphenylbut-2-namide (3c) followed by 2-(4-oxo-4,5-dihydrothiazol-2-yl)-3-phenyl-but-2-enoic acid-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-amide ( ...201324129248
public health significance of dermatophytes in ismailia and port said provinces, egypt.[corrected] dermatophytes are common in both developed and developing countries, the species involved and the resulting clinical entities vary geographically.201323760076
public health significance of dermatophytes in ismailia and port said provinces, egypt.[corrected] dermatophytes are common in both developed and developing countries, the species involved and the resulting clinical entities vary geographically.201323760076
evaluation of bioactivities of chlorokojic acid derivatives against dermatophytes couplet with cytotoxicity.in an attempt to find novel antifungal agents with improved activity, a series of compounds bearing 6-chloromethyl-3-hydroxy-2-substituted 4h-pyran-4-one moiety were synthesized and examined for their cytotoxic evaluation and antifungal activities against both standard and isolated dermatophytic fungal species microsporum gypseum, trichophyton mentagrophytes var. erinacei and epidermophyton floccosum.201323664872
evaluation of bioactivities of chlorokojic acid derivatives against dermatophytes couplet with cytotoxicity.in an attempt to find novel antifungal agents with improved activity, a series of compounds bearing 6-chloromethyl-3-hydroxy-2-substituted 4h-pyran-4-one moiety were synthesized and examined for their cytotoxic evaluation and antifungal activities against both standard and isolated dermatophytic fungal species microsporum gypseum, trichophyton mentagrophytes var. erinacei and epidermophyton floccosum.201323664872
the use of albino adult hair and blond prepubertal hair yields equivalent results in an in vitro hair perforation test to differentiate between different dermatophytic fungi.an in vitro hair perforation test is used to differentiate isolates of trichophyton mentagrophytes and trichophyton rubrum complexes because morphological criteria are insufficient. here, we performed in vitro hair perforation tests using blond prepubertal hair and albino adult hair to determine whether they differentiate between fungal species. we tested 43 well-characterized dermatophyte strains, arthroderma spp. [n = 4], epidermophyton floccosum [n = 1], microsporum spp. [n = 8], and trichoph ...201323591622
the use of albino adult hair and blond prepubertal hair yields equivalent results in an in vitro hair perforation test to differentiate between different dermatophytic fungi.an in vitro hair perforation test is used to differentiate isolates of trichophyton mentagrophytes and trichophyton rubrum complexes because morphological criteria are insufficient. here, we performed in vitro hair perforation tests using blond prepubertal hair and albino adult hair to determine whether they differentiate between fungal species. we tested 43 well-characterized dermatophyte strains, arthroderma spp. [n = 4], epidermophyton floccosum [n = 1], microsporum spp. [n = 8], and trichoph ...201323591622
identification of dermatophytes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.in this study we evaluated the suitability of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) for the identification of dermatophytes in diagnostic laboratories. first, a spectral database was built with 108 reference strains belonging to 18 species of the anamorphic genera epidermophyton, microsporum and trichophyton. all strains were well characterized by morphological criteria and its sequencing (gold standard). the dendrogram resulting from maldi-t ...201323228046
in vitro antifungal activity of micafungin and caspofungin against dermatophytes isolated from china.the aims of this study are to investigate the in vitro activities of micafungin and caspofungin that are two new echinocandin antifungal drugs against clinically isolated dermatophytes in china and to define mec (minimal effective concentration) as the reading endpoints of this study in accordance with (clinical and laboratory standards institute) clsi m38-a2 reference.201322983900
in vitro antifungal activity of micafungin and caspofungin against dermatophytes isolated from china.the aims of this study are to investigate the in vitro activities of micafungin and caspofungin that are two new echinocandin antifungal drugs against clinically isolated dermatophytes in china and to define mec (minimal effective concentration) as the reading endpoints of this study in accordance with (clinical and laboratory standards institute) clsi m38-a2 reference.201322983900
tinea infection with scutula-like lesions caused by microsporum gypseum in a sle patient: case report and literature review.scutula are characteristic lesions of tinea favosa or favus; the most frequently identified causative organism is trichophyton schoenleinii. although scutula-like lesions were described in microsporum gypseum infection, their presence on glabrous skin in a patient with sle has not been reported previously. we report a case of tinea infection with scutula-like lesions caused by microsporum gypseum in a sle patient, who was treated with topical terbinafine cream, and the lesions resolved completel ...201323912467
tinea infection with scutula-like lesions caused by microsporum gypseum in a sle patient: case report and literature review.scutula are characteristic lesions of tinea favosa or favus; the most frequently identified causative organism is trichophyton schoenleinii. although scutula-like lesions were described in microsporum gypseum infection, their presence on glabrous skin in a patient with sle has not been reported previously. we report a case of tinea infection with scutula-like lesions caused by microsporum gypseum in a sle patient, who was treated with topical terbinafine cream, and the lesions resolved completel ...201323912467
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