Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| the effects of tetracycline, minocycline, doxycycline and ofloxacin on prevotella intermedia biofilm. | prevotella intermedia, a black-pigmented, anaerobic, gram-negative bacterium, is associated with various type of periodontitis. antibiotic treatments via a systemic or local route have been reported as being useful for treating periodontal disease. the purpose of this study was to examine the effects of four antibiotics, tetracycline (tet), minocycline (mino), doxycycline (doxy) and ofloxacin (oflx) on p. intermedia biofilms at minimum inhibitory concentrations (mic) from one-fold to 100-fold. m ... | 2006 | 17064394 |
| transcriptional organization, regulation and role of the porphyromonas gingivalis w83 hmu haemin-uptake locus. | porphyromonas gingivalis, an oral bacterium associated with periodontal disease, requires haemin for growth. although several multigenic clusters encoding haemin-uptake systems are present on the genome of p. gingivalis, little is known regarding their transcriptional organization and expression. this study identified a 23 kda iron-regulated haemin-binding protein encoded by a larger than previously reported variant of hmuy. it was shown that the hmu locus is larger than previously reported and ... | 2006 | 17074906 |
| cytokine production in human periodontal ligament cells stimulated with porphyromonas gingivalis. | although some functions and characterizations of human periodontal ligament (hpdl) cells have been reported, the role of hpdl cells in periodontal disease is poorly understood. we have previously reported that hpdl cells produce many kinds of inflammatory cytokines by stimulation with prevotella intermedia. in this study, we examined the production of cytokines in hpdl cells stimulated with porphyromonas gingivalis as compared with p. intermedia. | 2006 | 17076781 |
| degradation of human hemoglobin by prevotella intermedia. | in this study, the ability of prevotella intermedia, an obligate anaerobic rod, to degrade human hemoglobin was determined by sds-page and the degradation was quantified by scanning densitometry. both bacterial cells and culture supernatants degraded hemoglobin. the hemoglobin degradation by p. intermedia was time-dependent, heat sensitive, ph related and was not influenced by iron restriction. inhibition studies demonstrated that a cysteine protease might be involved in hemoglobin degradation a ... | 2006 | 17081784 |
| one stage full-mouth disinfection--treatment of choice? | 2006 | 17092248 | |
| effects of sonicated prevotella intermedia, fusobacterium nucleatum and lactobacillus casei extracts on interleukin-8 production by human dental pulp cells. | the objective of this study was to determine the effects of prevotella intermedia, fusobacterium nucleatum and lactobacillus casei on the production of il-8 by human dental pulp cells. human dental pulp cells from teeth of young patients (aged 18-25 years) were cultured and tested with sonicated p. intermedia atcc 25611, f. nucleatum atcc 25586 and l. casei atcc 4646 extracts. il-8 secreted into the culture supernatants were measured at 6, 12 and 24 hours using a quantitative sandwich enzyme imm ... | 2006 | 17120973 |
| [streptococcus constellatusas a causative agent of empyema. report of one case]. | streptococcus constellatus is a commensal microorganism in man but may cause infections in different locations. we report a 59 years old male with severe sequelae of a previous cerebrovascular accident that consulted in the emergency room for fever of 15 days of evolution. a right empyema was diagnosed. the bacteriological culture of the effusion disclosed the presence of streptococcus constellatus and two anaerobic strains (prevotella intermedia and fusobacterium urealyticus). the patient was t ... | 2006 | 17130992 |
| phylogenetic analysis of bacterial and archaeal species in symptomatic and asymptomatic endodontic infections. | phylogenetic analysis of bacterial and archaeal 16s rrna was used to examine polymicrobial communities within infected root canals of 20 symptomatic and 14 asymptomatic patients. nucleotide sequences from approximately 750 clones amplified from each patient group with universal bacterial primers were matched to the ribosomal database project ii database. phylotypes from 37 genera representing actinobacteria, bacteroidetes, firmicutes, fusobacteria and proteobacteria were identified. results were ... | 2007 | 17172525 |
| outer membrane proteome of prevotella intermedia 17: identification of thioredoxin and iron-repressible hemin uptake loci. | although hemin is an indispensable nutrient for the oral pathogen prevotella intermedia, not much is known regarding the molecular mechanisms of hemin acquisition. the availability of the genomic sequence of the bacterium allowed us to apply proteomic approaches to identify proteins that may be mediating the hemin acquisition process. as hemin acquisition mechanisms have been shown to be induced in iron-depleted conditions, we applied proteomic approaches to detect those proteins whose expressio ... | 2007 | 17177252 |
| periodontal and oral microbiological status of an adult population undergoing haemodialysis: a cross-sectional study. | the aim of this cross-sectional study was to evaluate the periodontal status and oral microbiological patterns of a population with end-stage renal disease (esrd), undergoing haemodialysis (hd). | 2007 | 17305623 |
| microbiological outcomes of quadrant versus full-mouth root planing as monitored by real-time pcr. | to study the short-term microbiological changes following full-mouth compared with quadrant wise scaling and root planing (fmrp and qrp) as well as long-term effects. | 2007 | 17309590 |
| effects of oxidative stress on the virulence profile of prevotella intermedia during experimental infection in gnotobiotic mice. | prevotella intermedia is a component of the indigenous microbiota but is also responsible for anaerobic infections of the gastrointestinal tract and oral cavity. the aim of the present study was to investigate the influence of oxidative stress on the in vivo pathogenicity of p. intermedia. germ-free mice were challenged intraperitoneally with parental (wt) or oxidative stress adapted (aero) strains. bacterial virulence was evaluated by histopathology, hyperaemia and blood analysis [c-reactive pr ... | 2007 | 17314356 |
| a comparison of implant-supported, bar- or ball-retained mandibular overdentures: a retrospective clinical, microbiologic, and immunologic study of 10 edentulous patients attending a recall visit. | clinical, microbiologic, and immunologic comparisons of the peri-implant health in edentulous volunteers wearing long-standing implant-supported ball- or dolder bar-retained mandibular overdentures were performed. | 2007 | 17319360 |
| subgingival chlorhexidine varnish administration as an adjunct to same-day full-mouth root planing. ii. microbiological observations. | recently, the clinical additive value of a highly concentrated chlorhexidine (chx) varnish, when applied subgingivally as an adjunct to scaling and root planing, was described. the objective of the present study was to investigate the microbiological impact of a treatment strategy for chronic periodontitis based on a combination of same-day full-mouth root planing and subgingival chx varnish administration. | 2007 | 17335366 |
| the detection of eight putative periodontal pathogens in adult and rapidly progressive periodontitis patients: an institutional study. | periodontal disease is a commonly prevalent problem faced alike by both the developed and third world countries but showing wide variations in prevalence and severity across different geographical areas. the purpose was to identify actinobacillus actinomycetemcomitans (aa), porphyromonas gingivalis (pg), prevotella intermedia (pi), ekinella corrodens (ec), campylobacter rectus (cr), bacteroides forsythus (bf), treponema denticola (td) and fusobacterium nucleatum (fn) in indian adult periodontiti ... | 2007 | 17347537 |
| evidence of periopathogenic microorganisms in placentas of women with preeclampsia. | periodontal disease is a chronic inflammatory infectious disease that may act as a focus of infection. preeclampsia is a pregnancy-specific hypertensive disorder that often leads to maternal morbidity and mortality. acute atherosis, the placental lesion of preeclampsia, shares many histopathological features with atherosclerosis. recently, chronic infection was linked to the initiation of atherosclerosis. oral pathogens have been detected in atherosclerotic plaques, where they may play a role in ... | 2007 | 17397314 |
| correlation between atherosclerosis and periodontal putative pathogenic bacterial infections in coronary and internal mammary arteries. | chronic infections, such as periodontitis, have been associated with an increased risk for atherosclerosis and coronary artery disease. the aim of this study was to investigate biopsy samples of coronary and internal mammary arteries for the presence of putative pathogenic bacteria (porphyromonas gingivalis, actinobacillus actinomycetemcomitans, prevotella intermedia, and tannerella forsythensis), chlamydia pneumoniae, and human cytomegalovirus (cmv). | 2007 | 17397315 |
| periodontal pathogens in periodontal pockets and in carotid atheromatous plaques. | in the last years the relationship between periodontitis and cardiovascular diseases has been a subject of increasing research. the identification of periodontopathic bacteria in atheromas can contribute to our knowledge of such an association. the aim of our study was to assess the concomitant presence of 5 periodontal pathogens (actinobacillus actinomycetemcomitans, prevotella intermedia, porphyromonas gingivalis, treponema denticola, and tannerella forsythia) in periodontal pockets and in car ... | 2007 | 17452955 |
| persistently high levels of periodontal pathogens associated with preterm pregnancy outcome. | few studies examining the association between periodontal diseases and preterm birth have explored the underlying microbial and antibody responses associated with oral infection. | 2007 | 17470016 |
| periopathogenic bacteria in persistent periapical lesions: an in vivo prospective study. | the aim of this in vivo prospective study was to detect the presence of periopathogenic bacteria in persistent periapical lesions and to compare the reliability of two different methods: anaerobic culture and the dna hybridization technique. | 2007 | 17470025 |
| comparison of curet and paper point sampling of subgingival bacteria as analyzed by real-time polymerase chain reaction. | the outcome of microbiological diagnostics may depend on the sampling technique. it was the aim of the present study to compare two widely used sampling techniques for subgingival bacteria using quantitative real-time polymerase chain reaction. | 2007 | 17470026 |
| herpesviral-bacterial synergy in the pathogenesis of human periodontitis. | periodontitis is an infectious disease, but the specific mechanisms by which tooth-supportive tissues are lost remain obscure. this article proposes an infectious disease model for periodontitis in which herpesviral-bacterial interactions assume a major etiopathogenic role. | 2007 | 17471038 |
| activation of toll-like receptors 2 and 4 by gram-negative periodontal bacteria. | periodontitis is a chronic infectious disease associated with a gram-negative subgingival microflora. bacterial components stimulate, among other receptors, toll-like receptor (tlr) 2 and/or tlr4. accumulating evidence indicates that both qualitatively and quantitatively distinct immune responses result from the triggering of tlr2 as compared to tlr4 triggering. the aim was to study the interaction of porphyromonas gingivalis, actinobacillus actinomycetemcomitans, tannerella forsythensis, prevot ... | 2007 | 17488439 |
| odontogenic bacteria in periodontal disease and resistance patterns to common antibiotics used as treatment and prophylaxis in odontology in spain. | resistance in streptococci or gram-negative bacteria is associated with antibiotic consumption. scarce information exists on the antibiotic susceptibility of bacterial isolates from patients with periodontitis in countries with high antibiotic consumption, as this is an area in which microbiological testing is not performed in daily practice. the present study was undertaken to explore the susceptibility of bacterial isolates in periodontitis to antibiotics prescribed in odontology in spain as t ... | 2007 | 17530037 |
| bacterial species in subgingival plaque and oral bone loss in postmenopausal women. | oral bacteria are widely recognized in the etiology of periodontal disease. we investigated the prevalence of subgingival bacterial infection with eight species, tested associations between infection and oral bone loss, and assessed potential confounding factors and effect modifiers of those associations in a large community-based cohort of postmenopausal women. | 2007 | 17539719 |
| [subgingival microbiota in chronic and aggressive periodontitis in bogotá, colombia: an epidemiological approach]. | periodontitis-associated microbiotas differ in regions around the world and vary with a variety of factors. this suggests that each country must establish its own dental microbiobiotic profile in order to formulate adequate prevention measures and more specific treatments. | 2007 | 17546221 |
| microbiological findings after periodontal therapy using curettes, er:yag laser, sonic, and ultrasonic scalers. | to evaluate and compare the microbiological effects of hand instruments, er:yag-laser, sonic, and ultrasonic scalers in patients with chronic periodontitis. patient perception of each treatment was documented. | 2007 | 17555412 |
| oral bacterial lipopolysaccharide acts in mice to promote sensitisation to ovalbumin and to augment anaphylaxis via platelets. | microbial infection is thought to modulate allergic disorders, and we previously demonstrated that not only mast cells (which release histamine), but also platelets are involved in the anaphylaxis induced in mice sensitised to ovalbumin (ova). here, we examined the effects of a lipopolysaccharide (lps) from the oral bacterium prevotella intermedia (pi) on ova-induced anaphylaxis. upon intraperitoneal co-injection of pi-lps plus ova into balb/c mice, the pi-lps displayed a potent adjuvant effect ... | 2007 | 17559797 |
| population-based study of salivary carriage of periodontal pathogens in adults. | large, general population-based data on carriage rates of periodontal pathogens hardly exist in the current literature. the objectives of the present study were to examine the salivary detection of aggregatibacter (formerly actinobacillus) actinomycetemcomitans, campylobacter rectus, porphyromonas gingivalis, prevotella intermedia, tannerella forsythensis, and treponema denticola in a representative sample of the adult population living in southern finland and to clarify which determinants are a ... | 2007 | 17567788 |
| interleukin- 1 gene polymorphisms as assessed in a 10-year study of patients with early-onset periodontitis. | our 10-year study of early-onset periodontitis (eop) patients includes repeated clinical observations, microbiological characteristics and analysis of genetic polymorphism of il-1a and il-1b genes. twenty patients (age 15-26 years) were divided according to the clinical status in the 4th year into a group with mean number of teeth with bleeding on probing (bp) 9.8 and mean number of teeth with periodontal pocket (pp) 2.23, and a group with mean number of teeth with bp 5.37 and no pp. significant ... | 2007 | 17575917 |
| production of antagonistic substance by eikenella corrodens isolated from the oral cavity of human beings with and without periodontal disease. | antagonistic abilities may confer ecological advantages for micro-organisms in competitive ecosystems. however, reports regarding this phenomenon in eikenella corrodens are not available. | 2007 | 17584471 |
| quantification and characterization of synergistes in endodontic infections. | bacterial species belonging to the poorly characterized division synergistes have recently been reported in endodontic infections, and therefore may be part of the etiology of periradicular diseases. the objective of this study was to characterize and quantify the predominant synergistes phylotypes in infected root canals. | 2007 | 17600538 |
| adjunctive effects of systemic amoxicillin and metronidazole with scaling and root planing: a randomized, placebo controlled clinical trial. | the objective of this study was to investigate the effect of the systemic administration of metronidazole and amoxicillin as an adjunct to initial periodontal therapy in patients with moderate to severe chronic periodontitis. | 2007 | 17618330 |
| periodontal pathogens in erupting third molars of periodontally healthy subjects. | the presence of actinobacillus actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia and tannerella forsythensis in bacteriologic samples of 5-7-mm deep mandibular third-molar pericoronal pockets was analysed by polymerase chain reaction, to test the hypothesis that these sites would harbour the bacteria. the patients were periodontally healthy 20-year-old finnish male conscripts. sixteen had acute pericoronitis, 28 chronic pericoronitis, and 15 were symptom-free controls. a. ac ... | 2007 | 17629461 |
| gangrenous clostridium perfringens infection and subsequent wound management in a rhesus macaque (macaca mulatta). | a 10-y-old female rhesus macaque presented acutely with 3 large (diameter, greater than 4 cm), malodorous, ulcerogangrenous skin wounds on the left caudal thigh and calf. limb radiographs revealed free gas infiltrating deep tissues, and histologic examination confirmed myonecrosis. clostridium perfringens, staphylococcus aureus, and prevotella intermedia were isolated from the wounds. antimicrobials, analgesics, and aggressive debridement of necrotic skin and muscle resulted in immediate clinica ... | 2007 | 17645300 |
| targeted profiling of oral bacteria in human saliva and in vitro biofilms with quantitative real-time pcr. | an in vitro plaque model based on the use of human salivary bacteria and tooth-like surfaces was previously developed for studying the formation of oral biofilm and its use for pre-clinical testing of candidate antimicrobial or antiplaque agents. in this study, a quantitative taqman pcr assay (qpcr) was developed to compare the bacterial compositions of in vitro biofilms to parent saliva samples, and to determine the relative contributions of different species in the formation of the oral biofil ... | 2007 | 17653931 |
| diagnosis and anti-infective therapy of periodontitis. | periodontal diseases (gingivitis and periodontitis) are chronic bacterial infections with a remarkably high prevalence and morbidity. periodontitis, in contrast to gingivitis, is not reversible, is associated with certain bacterial species and affects all of the soft tissue and bone that support teeth. among the periodontal pathogens, species, such as aggregatibacter (actinobacillus) actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythensis, and several form ... | 2007 | 17678431 |
| duration-dependent susceptibility of endodontic pathogens to calcium hydroxide and chlorhexidene gel used as intracanal medicament: an in vitro evaluation. | the aim of this study was to evaluate the effective duration of antimicrobial activity of a calcium hydroxide-based medicament (apex cal) and 2% chlorhexidene gluconate gel against selected endodontic pathogens (enterococcus faecalis, candida albicans, porphyromonas gingivalis, and prevotella intermedia). the agar diffusion test was used to determine the antimicrobial activity. chlorhexidene gluconate gel showed the largest inhibitory zones. the antimicrobial action of both medicaments decreased ... | 2007 | 17689115 |
| prevotella intermedia lipopolysaccharide stimulates release of tumor necrosis factor-alpha through mitogen-activated protein kinase signaling pathways in monocyte-derived macrophages. | the purpose of this study was to investigate the effects of lipopolysaccharide from prevotella intermedia, a major cause of inflammatory periodontal disease, on the production of tumor necrosis factor (tnf)-alpha and the expression of tnf-alpha mrna in differentiated thp-1 cells, a human monocytic cell line. the potential involvement of the three main mitogen-activated protein kinase (mapk) signaling pathways in the induction of tnf-alpha production was also investigated. lipopolysaccharide from ... | 2007 | 17727652 |
| microbiologic analysis of periodontal pockets and carotid atheromatous plaques in advanced chronic periodontitis patients. | in recent years, many researchers have focused their attention on the ability of periodontal pathogens to colonize atheromatous plaques. nevertheless, a clear correlation between the detection rates of periodontopathic bacterial dna in atheromas and in subgingival plaque samples has not been established. the aim of our study was to assess the presence of five periodontal pathogens (actinobacillus actinomycetemcomitans, prevotella intermedia, porphyromonas gingivalis, treponema denticola, and tan ... | 2007 | 17760541 |
| periodontal microbiota in patients with coronary artery disease measured by real-time polymerase chain reaction: a case-control study. | recent data have shown that periodontal disease may increase the risk of occurrence of coronary heart disease in which inflammation initiated by bacteria and their compounds might be a common causal factor. this case-control study aimed at studying the relationship between periodontal disease and coronary artery disease (cad) based on clinical and periodontal microbiologic parameters. | 2007 | 17760542 |
| periodontopathic microorganisms in peripheric blood after scaling and root planing. | the objective of this study was to evaluate the frequency of periodontopathic and other subgingival anaerobic and facultative bacteria in the bloodstream following scaling and root planing (srp). | 2007 | 17850606 |
| structure and mutational analysis of the phon protein of salmonella typhimurium provide insight into mechanistic details. | the salmonella typhimurium phon protein is a nonspecific acid phosphatase and belongs to the phosphatidic acid phosphatase type 2 (pap2) superfamily. we report here the crystal structures of phosphate-bound phon, the phon-tungstate complex, and the t159d mutant of phon along with functional characterization of three mutants: l39t, t159d, and d201n. invariant active site residues, lys-123, arg-130, ser-156, gly-157, his-158, and arg-191, interact with phosphate and tungstate oxyanions. ser-156 al ... | 2007 | 17263560 |
| antimicrobial effect of triclosan and triclosan with gantrez on five common endodontic pathogens. | microbial control of the root canal system is one of the key objectives of root canal therapy. triclosan is a widely accepted broad spectrum antimicrobial agent proven to be effective against many gram-positive and gram-negative bacteria. triclosan acts by blocking bacterial fatty acid biosynthesis. the addition of gantrez copolymer has been shown to enhance the antimicrobial activity of triclosan. the purpose of this study was to determine the minimum inhibitory and bactericidal concentrations ... | 2007 | 17889698 |
| implant surface analysis and microbiologic evaluation of failed implants retrieved from smokers. | the aim of this study was to evaluate the microbiota and surface of failed titanium dental implants from 4 manufacturers. twelve mobile dental implants were retrieved from 10 smokers after 3 to 10 years of functional loading. before implant removal, microbial samples were taken and evaluated using polymerase chain reaction. after implant removal, analyses of the failed implant surfaces were performed using scanning electron microscopy and energy-dispersive spectrometer x-ray. periodontal pathoge ... | 2007 | 17912965 |
| innate immune responses of gingival epithelial cells to nonperiodontopathic and periodontopathic bacteria. | we have previously reported different susceptibilities of periodontopathic and nonperiodontopathic bacteria to antimicrobial peptides and phagocytosis by neutrophils. differences between the two groups of bacteria may exist also in their ability to induce immune responses from the host. therefore, we evaluated the effects of various oral bacteria on innate immune responses by gingival epithelial cells. | 2007 | 17956462 |
| antimicrobial activity of mahonia aquifolium and two of its alkaloids against oral bacteria. | extracts or alkaloids isolated from mahonia aquifolium exhibit antimicrobial activity against gram-positive and gram-negative bacteria, fungi, and protozoa. in this study the bacteriostatic and bacteriocidal activities of a m. aquifolium extract and two of its major alkaloids, berberine chloride and oxyacanthine sulphate, were tested in vitro against nine different oral bacteria. minimum inhibitory concentrations were in the range from < or = 0.0031% to 0.1993% for the m. aquifolium extract, fro ... | 2007 | 18072463 |
| high incidence of actinobacillus actinomycetemcomitans infection in acute coronary syndrome. | recent epidemiological studies suggest that periodontitis is an important risk factor for coronary heart disease (chd). the aim of this study was to evaluate the association between periodontitis and chd, particularly acute coronary syndrome (acs), focusing on microbiological and immunological features. twenty-eight chd patients, 15 with acs and 13 with chronic chd, were included in this study. coronary angiography, periodontal examination, and dental radiography were performed in all patients. ... | 2007 | 18160759 |
| hemin nutritional stress inhibits bacterial invasion of radicular dentine by two endodontic anaerobes. | to determine if anaerobic bacteria routinely found in infected dentine and root canals require the presence of heme in the environment in order for them to invade dentinal tubules. | 2007 | 17229113 |
| detection of porphyromonas gingivalis, porphyromonas endodontalis, prevotella intermedia, and prevotella nigrescens in chronic endodontic infection. | black-pigmented anaerobic rods such as prevotella spp. and porphyromonas spp. are involved in the etiology and perpetuation of endodontic infections. the aim of this study was to evaluate the prevalence of these species in chronic endodontic infections by using culture and polymerase chain reaction (pcr) techniques. samples of 100 patients with root canals displaying chronic endodontic infections were obtained by sterilized paper points. bacterial identification was performed by using culture an ... | 2007 | 17234549 |
| interleukin-1alpha stimulation in monocytes by periodontal bacteria: antagonistic effects of porphyromonas gingivalis. | periodontal pathogenic bacteria are associated with elevated levels of interleukin-1alpha (il-1alpha) but it is unclear if all species can induce cytokine production equally. porphyromonas gingivalis may be able antagonize il-1alpha induced by other species through the activity of its proteases or lipopolysaccharide (lps). monomac-6 cells and primary human monocytes were treated with culture supernatants from porphyromonas gingivalis, fusobacterium nucleatum, campylobacter rectus, actinobacillus ... | 2007 | 17241171 |
| elevated igg titers to periodontal pathogens related to buerger disease. | periodontal pathogens were frequently detected in the occluded arteries of buerger disease patients, hence we hypothesized that the infection from periodontal pathogens may be associated with buerger disease. | 2007 | 17207873 |
| comparison of subgingival bacterial sampling with oral lavage for detection and quantification of periodontal pathogens by real-time polymerase chain reaction. | saliva has been studied for the presence of subgingival pathogens in periodontitis patients. with the anaerobic culture technique, the discrepancy between salivary recovery and subgingival presence has been significant, which makes this approach not suitable for practical use in the microbial diagnosis of periodontitis patients. the real-time polymerase chain reaction (pcr) technique represents a very sensitive technique to detect and quantify bacterial pathogens. the aim of the study was to com ... | 2007 | 17199543 |
| comparative study of the antimicrobial efficacy of chlorhexidine gel, chlorhexidine solution and sodium hypochlorite as endodontic irrigants. | the purpose of this study was to assess the in vitro the antimicrobial efficacy of chlorhexidine gluconate gel as an endodontic auxiliary chemical substance compared to sodium hypochlorite (naocl) and chlorhexidine gluconate solution. the antimicrobial efficacy of the tested substances was evaluated using the agar diffusion test. the growth inhibition zones produced by 0.2%, 1% and 2% chlorhexidine gel were evaluated against 5 facultative anaerobic bacteria and 4 pigmented gram-negative anaerobe ... | 2007 | 18278298 |
| the influence of molecular oxygen exposure on the biology of prevotella intermedia, with emphasis on its antibiotic susceptibility. | this study focuses on investigating the molecular and physiological characteristics of prevotella intermedia after molecular oxygen exposure (moe) and the effect on drug susceptibility patterns. | 2007 | 17897190 |
| [prediction on the efficacy of fluoroquinolones for anaerobic infections using monte carlo simulation]. | various analysis based on pk-pd (pharmacokinetics-pharmacodynamics) theory were performed for prediction on the efficacy of antimicrobial agents for infectious diseases. however, there have been few reports when causative organisms would be anaerobic bacteria. although the antimicrobial activity of fluoroquinolones against anaerobes has been weak, gatifloxacin (gflx), moxifloxacin (mflx), and garenoxacin (grnx) are considered as anti-anaerobic quinolones in recent days. therefore, we investigate ... | 2007 | 18447205 |
| comparative analysis of putative periodontopathic bacteria by multiplex polymerase chain reaction. | the polymerase chain reaction (pcr) has been applied for the rapid and specific detection of periodontopathic bacteria in subgingival plaque and is potentially of clinical benefit in the diagnosis and treatment of periodontitis subjects. however, several technical points need to be modified before the conventional pcr detection system can be used by clinicians. | 2008 | 18447853 |
| nd:yag laser clinical assisted in class ii furcation treatment. | the nd:yag laser efficacy associated with conventional treatment for bacterial reduction has been investigated throughout literature. the purpose of this study was to evaluate the bacterial reduction after nd:yag laser irradiation associated with scaling and root planning in class ii furcation defects in patients with chronic periodontitis. thirty-four furcation lesions were selected from 17 subjects. the control group received conventional treatment, and the experimental group received the same ... | 2008 | 17899310 |
| treatment outcomes of dental flossing in twins: molecular analysis of the interproximal microflora. | the purpose of this study was to assess the effects of dental flossing on the microbial composition of interproximal plaque samples in matched twins. | 2008 | 18672992 |
| interferon-gamma and interleukin-12 gene polymorphisms and their relation to aggressive and chronic periodontitis and key periodontal pathogens. | the gene polymorphisms interferon-gamma (ifn-gamma) 874 t/a and interleukin (il)-12 1188 a/c have been associated with the altered production of cytokines. therefore, they might be indicative of the occurrence of chronic periodontitis (cp) or aggressive periodontitis (agp) and the prevalence of key periodontal pathogens. for this purpose, we analyzed these polymorphisms in subjects with generalized agp or generalized cp. moreover, we assessed the relationship between these polymorphisms and five ... | 2008 | 18672993 |
| [study of adherence of periodontal pathogens to collagen-treated hydroxyapatite]. | the ability of oral bacteria to adhere to tooth surface is associated with their pathogenicity. the objective of this study was to compare the ability of 4 strains of periodontal pathogens attaching to collagen-treated hydroxyapatite (c-ha) beads in order to evaluate the ability of the main periodontal pathogens to form the biofilm on root surface. | 2008 | 18705525 |
| antiviral, antibacterial and vitamin c-synergized radical-scavenging activity of sasa senanensis rehder extract. | sasa senanensis rehder extract (se) showed slightly higher cytotoxicity against human squamous cell carcinoma cell lines and human glioblastoma cell lines, as compared with human oral normal cells (gingival fibroblast, pulp cell, periodontal ligament fibroblast), and was more cytotoxic to human myelogenous and t-cell leukemia cell lines. se showed a bacteriostatic effect on fusobacterium nucleatum and prevotella intermedia, but almost completely eliminated hydrogen sulfide (h2s) and methyl merca ... | 2008 | 18712174 |
| photodynamic therapy as an adjunct to non-surgical periodontal treatment: a randomized, controlled clinical trial. | recent preclinical and clinical data have suggested a potential benefit of photodynamic therapy (pdt) in the treatment of periodontitis. however, there are very limited data from controlled clinical trials evaluating the effect of pdt in the treatment of periodontitis. the aim of this study was to evaluate the clinical and microbiologic effects of the adjunctive use of pdt to non-surgical periodontal treatment. | 2008 | 18771363 |
| rapid identification of oral anaerobic bacteria cultivated from subgingival biofilm by maldi-tof-ms. | to facilitate the identification of anaerobes cultivated from periodontal disease, whole cell bacterial identification by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof-ms) was evaluated. | 2008 | 18793359 |
| antiplaque/antigingivitis efficacy and safety of a cetylpyridinium chloride/zinc gluconate mucoadhesive gel. results of a 6-month clinical trial. | this article presents the results of a controlled clinical trial evaluating a new at-home treatment to improve gingival health. designed for overnight application at the gingival margins and in the interproximal spaces, the product is a mucoadhesive gel containing 0.10% cetylpyridinium chloride (cpc) and 0.592% zinc gluconate (zg). the authors assessed the efficacy and safety of the cpc/zg gel in adults with low-to-moderate gingival and plaque index scores by comparing clinical and laboratory fi ... | 2008 | 18795647 |
| antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria. | ginger (zingiber officinale roscoe) has been used widely as a food spice and an herbal medicine. in particular, its gingerol-related components have been reported to possess antimicrobial and antifungal properties, as well as several pharmaceutical properties. however, the effective ginger constituents that inhibit the growth of oral bacteria associated with periodontitis in the human oral cavity have not been elucidated. this study revealed that the ethanol and n-hexane extracts of ginger exhib ... | 2008 | 18814211 |
| periodontal bacterial profiles in pregnant women: response to treatment and associations with birth outcomes in the obstetrics and periodontal therapy (opt) study. | a recent clinical trial (obstetrics and periodontal therapy [opt] study) demonstrated that periodontal therapy during pregnancy improved periodontal outcomes but failed to impact preterm birth. the present study evaluated seven target bacteria, aggregatibacter actinomycetemcomitans (previously actinobacillus actinomycetemcomitans), porphyromonas gingivalis, treponema denticola, tannerella forsythia (previously t. forsythensis), prevotella intermedia, campylobacter rectus, and fusobacterium nucle ... | 2008 | 18834241 |
| correlates of periodontal decline and biologic markers in older adults. | there is limited information on infectious and host responses distinguishing older people with or without active periodontitis. this study measured bacterial and serum cytokine and high-sensitivity c-reactive protein (hscrp) levels in older persons. | 2008 | 18834247 |
| detection of periodontal pathogens in oral mucous membranes of edentulous individuals. | the purpose of this study was to investigate the colonization of campylobacter rectus, porphyromonas gingivalis, aggregatibacter actinomycetemcomitans (previously actinobacillus actinomycetemcomitans), prevotella intermedia, and tannerella forsythia (previously t. forsythensis) in the tongue and cheek of newborns and elderly individuals with no teeth. | 2008 | 18834252 |
| periodontal conditions and distribution of prevotella intermedia, porphyromonas gingivalis and aggregatibacter actinomycetemcomitans in hiv-infected patients undergoing anti-retroviral therapy and in an hiv-seronegative group of the venezuelan population. | the aim of this study was to determine the periodontal conditions and the distribution of prevotella intermedia, porphyromonas gingivalis and aggregatibacter actinomycetemcomitans in a group of hiv-infected patients undergoing anti-retroviral therapy (haart) and in an hiv-seronegative group. the study sample comprised thirty-two (32) hiv positive patients distributed in two groups (11 hiv+ without haart and 21 hiv+ with haart) and 16 hiv seronegative patients. plaque index, gingival index, pocke ... | 2008 | 18841752 |
| characterization of oral lactobacilli as potential probiotics for oral health. | intestinal lactobacilli have been successfully used as probiotics to treat gastrointestinal disorders, but only limited data are available for the probiotic properties of oral lactobacilli to combat oral diseases. we aimed to characterize oral lactobacilli for their potential probiotic properties according to the international guidelines for the evaluation of probiotics, and to select potential probiotic strains for oral health. | 2008 | 18279182 |
| etiological analysis of initial colonization of periodontal pathogens in oral cavity. | it is unclear when the initial colonization by periodontal pathogens occurs in the oral cavity. therefore, we report here the association between specific age groups and the time when the initial colonization by periodontal pathogens occurs in the oral cavity in such groups. findings are based on an epidemiological analysis of the prevalence of five periodontal pathogens in the oral cavities of a wide range of age populations, from newborn to elderly, who were randomly selected in a geographic r ... | 2008 | 18287326 |
| colonization pattern of periodontal bacteria in japanese children and their mothers. | the purpose of this study was to determine the time of infection by anaerobic gram-negative rods associated with periodontal disease, and to clarify their transmission from mother to child. | 2008 | 18302616 |
| antimicrobial susceptibility of periodontopathogenic bacteria. | the aim of this study was to evaluate the resistance profiles of aggregatibacter (actinobacillus) actinomycetemcomitans, porphyromonas gingivalis and prevotella intermedia/prevotella nigrescens and to detect possible changes in antibiotic resistance over the time period of 1991-2005. | 2008 | 18326855 |
| [the effect of different roughness of crown alloy materials on the adhesion of predominant peri-implant subgingival bacteria]. | to investigate the effect of two crown metal alloys with different roughness on the adhesion of predominant subgingival bacteria. | 2008 | 18360673 |
| genetic markers of tumour necrosis factor alpha in aggressive and chronic periodontitis. | tumour necrosis factor alpha (tnfalpha) plays an important role in the pathogenesis of periodontitis. tnfalpha production is influenced by gene polymorphisms. the aim of this study was to evaluate links between genetic variants and chronic/aggressive periodontitis in a multivariate model. | 2008 | 18363738 |
| the reproducibility of curet sampling of subgingival biofilms. | because few studies have examined the critical issue of sampling reproducibility, the purpose of the present study was to examine the reproducibility of curet sampling of subgingival biofilms. | 2008 | 18380565 |
| [detection of periodontal pathogens in coronary atherosclerotic plaques]. | to explore the possible correlation between coronary heart disease and periodontitis. | 2008 | 18380965 |
| prevotella intermedia induces matrix metalloproteinase-9 expression in human periodontal ligament cells. | matrix metalloproteinases (mmps) play pivotal roles in inflammatory diseases including chronic periodontitis. the effects of prevotella intermedia, a major periodontal pathogen, on mmp-9 production in primary human periodontal ligament (hpdl) cells were examined in the present study. mmp-9 mrna expression was measured by semiquantitative reverse transcriptase pcr and its protein secretion was assayed by gelatin zymography. prevotella intermedia atcc 25611 supernatant time and dose-dependently in ... | 2008 | 18400000 |
| bleeding on probing differentially relates to bacterial profiles: the oral infections and vascular disease epidemiology study. | various bacterial species are differentially prevalent in periodontal health, gingivitis or periodontitis. we tested the independent associations between three bacterial groupings and gingival inflammation in an epidemiological study. | 2008 | 18400025 |
| effects of fixed orthodontic appliances on subgingival microflora. | fixed orthodontic appliances cause plaque accumulation around bands and brackets. since the microbiological composition of dental plaque is closely connected to periodontal tissue health, the aim of this study was to determine the effects of fixed orthodontic appliances on subgingival microflora and periodontal status. | 2008 | 18412726 |
| microbial analysis of canals of root-filled teeth with periapical lesions using polymerase chain reaction. | the objective of the present study was to investigate the presence of nine bacterial species in root-filled teeth associated with periapical lesions using a polymerase chain reaction analysis and to correlate these species with clinical features of the cases. dna was extracted from 45 canal samples of root-filled teeth with periapical lesions. a pcr assay using species-specific primers of 16s rdna and the downstream intergenic spacer region was used for microbial detection. enterococcus faecalis ... | 2008 | 18436030 |
| the prevalence of periodontopathogenic bacteria in saliva is linked to periodontal health status and oral malodour. | this study investigated whether an improvement in periodontal health resulted in changes in the prevalence of periodontopathogenic bacteria in saliva and tongue coatings and a reduction in volatile sulfur compounds (vscs: h(2)s and ch(3)sh) linked to oral malodour. the subjects were 35 patients who visited the breath odour clinic of kyushu dental college, japan. their mean age was 51.2+/-18.3 years (mean+/-sd). a clinical examination performed at baseline and 2 months after periodontal treatment ... | 2008 | 18436598 |
| antimicrobial effect and ph of chlorhexidine gel and calcium hydroxide alone and associated with other materials. | the purposes of this study were to evaluate the effectiveness of 2% chlorhexidine (chx) gluconate gel, calcium hydroxide [ca(oh)2] and their combination with iodoform and zinc oxide powder as intracanal medications against select microorganisms, and to measure the ph changes caused by these medications. antimicrobial activity was determined by the agar diffusion method. the zones of growth inhibition were measured and the results were analyzed statistically by kruskal-wallis test (p<0.05). the p ... | 2008 | 18438556 |
| photodynamic treatment of endodontic polymicrobial infection in vitro. | we investigated the photodynamic effects of methylene blue on multispecies root canal biofilms comprising actinomyces israelii, fusobacterium nucleatum subspecies nucleatum, porphyromonas gingivalis, and prevotella intermedia in experimentally infected root canals of extracted human teeth in vitro. the 4 test microorganisms were detected in root canals by using dna probes. scanning electron microscopy showed the presence of biofilms in root canals before therapy. root canal systems were incubate ... | 2008 | 18498901 |
| staphylococcus aureus and other bacteria in untreated periodontitis. | whether the subgingival microbiota differ between individuals with chronic and those with aggressive periodontitis, and whether smoking influences bacterial composition, is controversial. we hypothesized that the subgingival microbiota do not differ between sites in individuals with chronic or aggressive periodontitis, or by smoking status. bacterial counts and proportional distributions were assessed in 84 individuals with chronic periodontitis and 22 with aggressive periodontitis. no differenc ... | 2008 | 18502971 |
| the anti-endotoxic effects of the ksl-w decapeptide on escherichia coli o55:b5 and various oral lipopolysaccharides. | host responses following the recognition of bacterial lipopolysaccharide can range from acute inflammation to septic shock. the aim of this study was to evaluate the ability of the ksl-w decapeptide to bind to and block the endotoxic effects of lipopolysaccharide. | 2008 | 18503516 |
| the relationship of prevotella intermedia, prevotella nigrescens and prevotella melaninogenica in the supragingival plaque of children, caries and oral malodor. | a relationship between the distribution of periodontal bacteria species and malodor in children has not been sufficiently investigated. the present study was undertaken to determine the presence of 3 periodontopathic bacteria (prevotella spp. p. intermedia, p. nigrescens, p. melaninogenica) in the supragingival plaques of 3 to 16-year-old children with different oral health conditions and oral malodor. | 2008 | 18524268 |
| pcr-based identification of selected pathogens associated with endodontic infections in deciduous and permanent teeth. | the aim of the present study was to evaluate the presence of the selected pathogens in samples from deciduous and permanent tooth root canals by using pcr method and to determine the association of these organisms with clinical symptoms. | 2008 | 18547832 |
| [relationship between herpesviruses and periodontal pathogenic bacteria in subgingival plaque]. | to evaluate the prevalence rates of human cytomegalovirus(hcmv) and epstein-barr virus-1(ebv-1) in subgingival plaque and analyze the relationship between herpesviruses, periodontal pathogenic bacteria and periodontal clinical parameters in chinese patients with aggressive periodontitis(agp). | 2008 | 18560463 |
| rapid and simple detection of eight major periodontal pathogens by the loop-mediated isothermal amplification method. | loop-mediated isothermal amplification (lamp) was applied to develop a rapid and simple detection system for eight periodontal pathogens: aggregatibacter (actinobacillus) actinomycetemcomitans, campylobacter rectus, eikenella corrodens, fusobacterium nucleatum, porphyromonas gingivalis, prevotella intermedia, treponema denticola and tannerella forsythia. primers were designed from the 16s ribosomal rna gene for each pathogen, and the lamp amplified the targets specifically and efficiently under ... | 2008 | 18565108 |
| differential gender effects of a reduced-calorie diet on systemic inflammatory and immune parameters in nonhuman primates. | dietary manipulation, including caloric restriction, has been shown to impact host response capabilities significantly, particularly in association with aging. this investigation compared systemic inflammatory and immune-response molecules in rhesus monkeys (macaca mulatta). | 2008 | 18565132 |
| analysis of neutrophil-derived antimicrobial peptides in gingival crevicular fluid suggests importance of cathelicidin ll-37 in the innate immune response against periodontogenic bacteria. | during periodontitis, an innate immune response to bacterial challenge is primarily mediated by neutrophils. we compared neutrophilic content and the level of neutrophil-derived antimicrobial peptides in gingival crevicular fluid (gcf) in two clinical forms of severe periodontitis. | 2008 | 18582333 |
| relationship of porphyromonas gingivalis with glycemic level in patients with type 2 diabetes following periodontal treatment. | the aim of this study was to assess the relationship between serum glycemic levels and subgingival microbial profile alteration following periodontal treatment in patients with type 2 diabetes mellitus. | 2008 | 18582336 |
| microorganisms in root canal-treated teeth from a german population. | posttreatment apical periodontitis is usually associated with persistent or secondary intraradicular infection. this study evaluated the presence and relative levels of 28 bacterial taxa in treated root canals of teeth with posttreatment apical periodontitis from german patients using 16s ribosomal rna (rrna) gene probes in a reverse-capture checkerboard hybridization assay. species-specific polymerase chain reaction (pcr) was also performed to detect enterococcus faecalis and candida albicans. ... | 2008 | 18634922 |
| endodontic microorganism susceptibility by direct contact test. | the aim of this study was to evaluate in vitro the duration of the antimicrobial effect of endodontic sealers by means of the direct contact test. the sealers tested were: endomethasone - septodont, endomethasone c-septodont, endion-voco, diaket-espe, pulp canal sealer-sybronendo, and ah26-dentsply detrey. the endodontopathic microorganisms (mo) confronted were: staphylococcus aureus (sa), candida albicans (ca), enterococcus faecalis (ef), prevotella intermedia (pi), porphyromonas gingivalis (pg ... | 2008 | 19177855 |
| reduction of periodontal pathogens adhesion by antagonistic strains. | periodontitis results from a shift in the subgingival microflora into a more pathogenic direction with porphyromonas gingivalis, prevotella intermedia, and actinobacillus actinomycetemcomitans considered as periodontopathogens. in many cases, treatment procures only a temporary shift towards a less pathogenic microflora. an alternative treatment could be the deliberate colonization of pockets with antagonistic microorganisms to control the adhesion of periodontopathogens. the aim of this study w ... | 2008 | 18173797 |
| relationship between campylobacter rectus and periodontal status during pregnancy. | in a previous study, we showed that the growth of campylobacter rectus is stimulated by the presence of female sex hormones in the culture medium. in the present study, we examined the relationship between c. rectus levels in the saliva and the periodontal status of pregnant women. | 2008 | 18173799 |
| microflora in oral ecosystems in subjects with radiation-induced hyposalivation. | to analyse the microbial flora in specific oral sites in 13 dentate subjects, 6-8 months after completed radiation therapy (rt group) and in 13 matched controls. | 2008 | 18208474 |
| the interleukin-10 promoter haplotype ata is a putative risk factor for aggressive periodontitis. | interleukin-10 has been described as an anti-inflammatory cytokine and a b-cell proliferation factor. promoter polymorphisms of the interleukin-10 gene have been associated with altered interleukin-10 expression. therefore, the aim of this study was to evaluate three polymorphisms at positions -1082g>a, -819c>t and -590c>a in patients with generalized chronic periodontitis (n = 27) and generalized aggressive periodontitis (n = 32) in comparison with periodontitis-free controls (n = 34). | 2008 | 18230105 |