Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| bronchial allergen challenges in children - safety and predictors. | in allergic asthma, the diagnosis of house dust mite (hdm) allergy is mainly based on the patient's history, allergy testing by the skin prick test (spt) or the levels of allergen-specific ige. we retrospectively analysed data from 350 bronchial provocations with hdm and related it to the following parameters: specific ige, bronchial hyperresponsiveness (bhr) to methacholine testing (mct) and exhaled no (eno). | 2013 | 23331526 |
| the effect of pneumococcal polysaccharide vaccine in a mouse model of allergic rhinitis. | this study aimed to determine if pneumococcal polysaccharide vaccine (ppv) could suppress allergic inflammation in an allergic rhinitis mouse model and to explore whether differences exist regarding the effect of ppv according to timing of administration. | 2013 | 23314157 |
| correlation of symptoms with total ige and specific ige levels in patients presenting with allergic rhinitis. | the objective of this study was to investigate the correlation of symptoms in patients with presumed allergic rhinitis on the basis of their medical history and physical examination with the levels of total immunoglobulin e (ige) and specific ige, and to question the necessity of these tests in diagnosis. | 2013 | 23197073 |
| effects of catalpa ovata stem bark on atopic dermatitis-like skin lesions in nc/nga mice. | the stem bark of catalpa ovata has been used as a traditional herbal medicine for the treatment of various inflammatory diseases such as itching and scabies. | 2013 | 23195129 |
| the impact of pulmonary tuberculosis treatment on the prevalence of allergic rhinitis. | atopy is a syndrome characterized by immediate hypersensitivity reactions to common environmental antigens. the "hygiene hypothesis" stipulates that childhood infections are associated with a lower risk of allergies. not much has been published about the effects that the treatment of pulmonary tuberculosis (tb) has on allergies, specifically allergic rhinitis. we conducted a study to investigate the prevalence of allergic rhinitis in patients with pulmonary tb before and after treatment of their ... | 2013 | 23975489 |
| [ultrastructure of the digestive system in dermatophagoides farinae (acariformes:pyroglyphidae)]. | fifty living mites (dermatophagoides farinae) were fixed in 2.5% glutaraldehyde, postfixed in 1% osmium tetroxide, dehydrated in a graded ethanol series, embedded in embedding medium. the ultrastructure of the digestive tract in d. farinae was observed by serial ultrathin sections with a transmission electron microscope. the alimentary canal of d. farinae consists of the cuticle-lined foregut and hindgut separated by a microvilli-lined midgut (anterior midgut, posterior midgut). there are differ ... | 2013 | 24818423 |
| [the analysis of the allergens in 576 patients with allergic rhinitis in qingyang of gansu province]. | to investigate the allergens distribution of 576 allergic rhinitis patients in qingyang, and to provide basic epidemiologic information for the prevention and treatment of allergic rhinitis. | 2013 | 24620661 |
| house dust mites: a risk factor to be considered for occupational safety or source of work-related allergens. | house dust mites (hdm) can be found worldwide where human beings live independent from the climate and are a major source of multiple allergens. mite allergens sensitize and induce perennial rhinitis, asthma, or atopic dermatitis in a large portion of patients with allergic disease particularly children. there is convincing evidence that avoidance of mite allergen can effectively reduce allergic symptoms. this study examined dust from a military hospital and the private home of some nursing staf ... | 2013 | 24640866 |
| the role of molds in the relation between indoor environment and atopy in asthma patients. | the effect of mold fungi to allergic sensitization is not well-known. we aimed to evaluate the role of molds in the relation between indoor environment and atopy in asthmatics. | 2013 | 24523798 |
| [efficacy of sublingual immunotherapy with dermatophagoides farinae drops in preschool and school-age children with allergic asthma and allergic rhinitis]. | to evaluate the efficacy of specific sublingual immunotherapy (slit) with dermatophagoides farinae drops on children with allergic asthma and allergic rhinitis of the preschool and school-age groups of children and adolescents. | 2013 | 24484557 |
| influence of the adjuvants and genetic background on the asthma model using recombinant der f 2 in mice. | der f 2 is the group 2 major allergen of a house dust mite (dermatophagoides farinae) and its function has been recently suggested. to determine the optimal condition of sensitization to recombinant der f 2 (rder f 2) in murine model of asthma, we compared the effectiveness with different adjuvants in balb/c and c57bl/6 mice. mice from both strains sensitized with rder f 2 by intraperitoneal injection or subcutaneous injection on days 1 and 14. the dosage was 20 µg. freund's adjuvants with pertu ... | 2013 | 24385949 |
| therapeutic effects and immunomodulation of suanbo mineral water therapy in a murine model of atopic dermatitis. | balneotherapy is widely used as an alternative treatment modality for ad. although the clinical benefit of some mineral waters has been established, their mechanisms of action in alleviating ad are only partly understood. | 2013 | 24371394 |
| [analysis of mite-allergic characteristics in patients with allergic rhinitis]. | to investigate the characteristics of allergic rhinitis sensitized with mite, providing the evidence for the treatment plan of allergic rhinitis in tianjin area. | 2013 | 24358792 |
| the drinking effect of hydrogen water on atopic dermatitis induced by dermatophagoides farinae allergen in nc/nga mice. | hydrogen water (hw) produced by electrolysis of water has characteristics of extremely low oxidation-reduction potential (orp) value and high dissolved hydrogen (dh). it has been proved to have various beneficial effects including antioxidant and anti-inflammatory effects; however, hw effect on atopic dermatitis (ad), an inflammatory skin disorder, is poorly documented. in the present study, we examined the immunological effect of drinking hw on dermatophagoides farinae-induced ad-like skin in n ... | 2013 | 24348704 |
| the effect of rhinovirus on airway inflammation in a murine asthma model. | the aim of the present study was to investigate the differences in lower airway inflammatory immune responses, including cellular responses and responses in terms of inflammatory mediators in bronchoalveolar lavage fluid (balf) and the airway, to rhinovirus (rv) infection on asthma exacerbation by comparing a control and a murine asthma model, with or without rv infection. | 2013 | 24348661 |
| alpha-actinin is a new type of house dust mite allergen. | main indoor allergens for humans are from house dust mites. there are more than 30 allergens in dermatophagoides farinae but only fourteen allergens have been identified from this mite including der f 1-3, 6, 7, 10, 11, 13-18, and 22. a native allergen protein (der f 24, 90 kda) was purified from d. farinae by gel filtration and anionic exchange liquid chromatography combined with ige immunodetection. its primary structure was determined by edman degradation, mass spectrometry analysis and cdna ... | 2013 | 24324688 |
| 7,3',4'-trihydroxyisoflavone ameliorates the development of dermatophagoides farinae-induced atopic dermatitis in nc/nga mice. | atopic dermatitis is an inflammatory and chronically relapsing skin disorder that commonly occurs in children; the number of atopic dermatitis patients is increasing. the cause and mechanism of atopic dermatitis have not been defined clearly, although many studies are ongoing. epidemiological studies suggest that soybean and its isoflavones have immunoregulatory activities. here, we report that 7,3',4'-trihydroxyisoflavone (7,3',4'-thif), a major metabolite of daidzin, effectively inhibited lipo ... | 2013 | 24324516 |
| [efficacy of sublingual immunotherapy with dermatophagoides farinae drops in monosensitized and polysensitized patients with allergic rhinitis]. | to compare the efficacy of sublingual immunotherapy (slit) with standardized dermatophagoides farinae drops in monosensitized and polysensitized patients with allergic rhinitis. | 2013 | 24313202 |
| verbenone structural analogues isolated from artemesia aucheri as natural acaricides against dermatophagoides spp. and tyrophagus putrescentiae. | the acaricidal activities of artemisia aucheri oil and (1s)-(-)-verbenone structural analogues were evaluated using a fumigant method against dermatophagoides farinae , dermatophagoides pteronyssinus , and tyrophagus putrescentiae and then compared to those of benzyl benzoate. on the basis of the ld50 values against d. farinae , (1s)-(-)-verbenone (1.38 μg/cm(2)) was about 7.4 times more active than benzyl benzoate (10.15 μg/cm(2)), followed by (+)-trans-myrtanol (2.27 μg/cm(2)), (-)-trans-myrta ... | 2013 | 24295367 |
| [analysis of clinical features and allergic status of asthmatic patients with positive serum mycosis-specific ige]. | to improve understanding of the clinical characteristics and diagnosis of allergic bronchopulmonary mycosis (abpm). | 2013 | 24252730 |
| epidemiology of ige-dependent allergic diseases in elderly patients in poland. | there is a growing allergy problem in elderly patients. the epidemiology of atopic bronchial asthma (ba), allergic rhinitis, and atopic dermatitis (ad) was analyzed in an elderly polish population. | 2013 | 24119595 |
| different anti-apoptotic effects of normal and asthmatic serum on normal eosinophil apoptosis depending on house dust mite-specific ige. | we investigated the effect of asthmatic serum on constitutive eosinophil apoptosis in normal subjects. eosinophil apoptosis in normal subjects was inhibited by asthmatic serum but not normal serum. in a detailed analysis based on the presence of house dust mite (hdm) ige, hdm ige-positive (+) asthmatic serum was more effective for eosinophil apoptosis than that of hdm ige-negative (-) asthmatic serum. hdm ige+ asthmatic serum inhibited both hdm ige- and hdm ige+ normal eosinophil apoptosis, and ... | 2013 | 24065529 |
| association between pet ownership and the sensitization to pet allergens in adults with various allergic diseases. | as pet ownership increases, sensitization to animal allergens due to domestic exposure is a concern. sensitization to animal allergens may occur from indirect exposure, as well as direct ownership of animals. however, there have been conflicting results regarding the association between pet ownership and sensitization to animal allergens in adults. | 2013 | 24003386 |
| [analysis of allergen variation for 3292 patients with allergic rhinitis]. | to investigate the variation of common allergens in patients with allergic rhinitis in recent 4 years in tianjin first center hospital. | 2013 | 24103176 |
| enzymatic activity of allergenic house dust and storage mite extracts. | proteases are involved in the pathogenicity of allergy, increasing epithelial permeability and acting as adjuvants. enzymatic activity is therefore important for the allergenicity of an extract and also affects its stability and safety. however, the enzymatic activity of extracts is not usually evaluated. the objective of this study was to evaluate the enzymatic activity of the most allergenic mite extracts and to investigate their allergenic properties. extracts from nine allergenic mite specie ... | 2013 | 23427664 |
| the toxic effect of chitosan/metal-impregnated textile to synanthropic mites. | plasma treatment enables effective binding of chitosan film to textile fibres. heavy metal ions such as ag(+) adsorbed onto the chitosan coating are known to enhance toxicity to microorganisms. the acaricidal effect of chitosan and chitosan/metal adducts with ag(+) , zn(2+) and cu(2+) was tested in laboratory experiments. tested species acarus siro, dermatophagoides farinae, d. pteronyssinus and tyrophagus putrescentiae are allergen producers and important pests in house dust, stored food and fe ... | 2013 | 23135827 |
| structural biology of mite allergens. | mite allergens contribute to a significant proportion of human allergic symptoms, including asthma and rhinitis. the development of therapies to treat and prevent these symptoms depends largely on our understanding of the properties of these allergens. much effort has been devoted to determining the structure and organization of mite allergens, particularly of the house dust mites, toward understanding their activities and how they elicit immunological responses in humans. here, we review the st ... | 2013 | 23054022 |
| [correlation of cutaneous reactivity between allergenic extracts of dermatophagoides pteronyssinus and dermatophagoides farinae with blomis tropicalis in patients with allergic rinitis and asthma]. | there are documented molecular homologies between mites from the same group, but intergroup characteristics are not. although mites share the same taxonomic order, there are species antigenically distinct. at the present we dont know clearly the differences in cutaneous reactivity among several house dust mites species. | 2013 | 24007986 |
| [relative potency of allergenic extracts from mites in patients with asthma and allergic rhinitis]. | skin tests for specific diagnosis of allergies require high quality extracts, which can be measured by the determination of allergenic potency, utilizing different concentrations of extracts from a manufacturer. | 2013 | 24007830 |
| prevalence of allergen sensitization, most important allergens and factors associated with atopy in children. | knowledge of the profile of allergen sensitization among children is important for planning preventive measures. the objective of this study was to assess the prevalence and profile of sensitization to inhaled allergens and food among children and adolescents in an outpatient population in the city of palmas. | 2013 | 24310798 |
| comparison of antiallergic effects of pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine in a murine model of allergic rhinitis. | pneumococcal vaccines have been widely used, and streptococcus pneumoniae has been suggested to be an effective therapeutic agent in allergic disease. | 2013 | 23417574 |
| [cloning, expression and analysis of der f mag 29 allergen of dermatophagoides farinae]. | the full-length mag 29 gene of dermatophagoides farinae was amplified by rt-pcr with a pair of specific primers. the pcr product was cloned into pcold tf dna vector. the constructed plasmid pcold tf-mag 29 was transformed into e. coli bl21 and followed by expression of the protein induced by iptg. the recombinant protein was analyzed by sds-page. the full-length mag 29 gene was 429 bp. a specific band (mr 63,000) were detected in the whole cells, the supernatant, and the precipitate. bioinformat ... | 2013 | 24818419 |
| [cloning, expression and identification of der f7 gene from dermatophagoides farinae and its immunological characteristics]. | to clone and express der f7 gene of dermatophagoides farinae, and identify its immunogenicity. | 2013 | 24818391 |
| the group 10 allergen of dermatophagoides farinae (acari: pyroglyphidae): cdna cloning, sequence analysis, and expression in escherichia coli bl21. | dermatophagoides farinae hughes, american house dust mite, is highly allergenic, producing symptoms in people worldwide. identifying and cloning the allergens in this species may enable better diagnostic and therapeutic approaches. here, we cloned, sequenced, and expressed the full-length cdna encoding d. farinae group 10 allergen (der f 10) isolated from dust mites in china. bioinformatic analysis indicated that the 888 bp sequence encoded a cytoskeleton protein 295 amino acids long, with a mol ... | 2013 | 23427671 |
| production of a chimeric allergen derived from the major allergen group 1 of house dust mite species in nicotiana benthamiana. | plants are widely accepted as a general platform for the large-scale production of recombinant proteins, which has been demonstrated by the successful expression of various exogenous proteins. using plants as a bioreactor for mass production of target proteins for vaccines is thought to show the most potential. this study explores whether a chimeric allergen r8, derived from the major allergen group 1 of house dust mites species (dermatophagoides farinae and dermatophagoides pteronyssinus), is e ... | 2013 | 23354320 |
| immunization of rabbits with nematode ascaris lumbricoides antigens induces antibodies cross-reactive to house dust mite dermatophagoides farinae antigens. | there are controversial reports on the relationship between helminthic infection and allergic diseases. although ige cross-reactivity between nematode ascaris antigens and house dust-mite allergens in allergic patients have been reported, whether ascaris or the mite is the primary sensitizer remains unknown. here we found that immunization of naïve animals with ascaris lumbricoides (al) antigens induced production of antibodies cross-reactive to mite antigens from dermatophagoides farinae (df). ... | 2013 | 23291773 |
| differential effects of dexamethasone and itraconazole on aspergillus fumigatus-exacerbated allergic airway inflammation in a murine model of mite-sensitized asthma. | fungal exposure is associated with particularly severe asthma. nevertheless, the effects of anti-fungal treatments on fungus-exacerbated asthma need to be determined. | 2013 | 23327882 |
| fungal food choices of dermatophagoides farinae affect indoor fungi selection and dispersal. | house dust mite (hdm) feces and molds are the main allergens involved in allergic asthma. differences exist between the housing fungal biome of allergic patients and standard or unhealthy housing. house dust mite (hdm) feed off spores and transport them on their bodies, but do they have fungal food preferences? we observed dermatophagoïdes farinae in vitro with 16 mold menus and repeated the experiment 10 times. this observation led us to define alternaria alternata, cladosporium sphaerospermum, ... | 2013 | 22774849 |
| [development of allergic rhinitis and its impact on asthma: 4-5 year follow-up study of preschool children]. | to observe the development of allergic rhinitis (ar) in preschool children, and the variation of sensitization to airborne allergens 5 years later, also the link between ar and asthma. | 2013 | 24444631 |
| the skin prick test - european standards. | skin prick testing is an essential test procedure to confirm sensitization in ige-mediated allergic disease in subjects with rhinoconjunctivitis, asthma, urticaria, anapylaxis, atopic eczema and food and drug allergy. this manuscript reviews the available evidence including medline and embase searches, abstracts of international allergy meetings and position papers from the world allergy literature. the recommended method of prick testing includes the appropriate use of specific allergen extract ... | 2013 | 23369181 |
| dermatophagoides farinae allergens diversity identification by proteomics. | the most important indoor allergens for humans are house dust mites (hdm). fourteen dermatophagoides farinae allergens (der f 1-3, 6, 7, 10, 11, 13-18, and 22) are reported although more than 30 allergens have been estimated in d. farinae. seventeen allergens belonging to 12 different groups were identified by a procedure of proteomics combined with two-dimensional immunoblotting from d. farina extracts. their sequences were determined by edman degradation, mass spectrometry analysis, and cdna c ... | 2013 | 23481662 |
| sensitisation to mites in a group of patients with asthma in yaounde, cameroon: a cross-sectional study. | sensitisation of asthmatic patients to mites in sub-saharan africa has been less described. the aim of this study was to assess the prevalence and determinants of sensitisation to mites in asthmatic adolescents and adults in yaounde, cameroon. | 2014 | 24390384 |
| atopic phenotypes identified with latent class analyses at age 2 years. | atopic sensitization (ie, atopy) is the most commonly reported risk factor for asthma. recent studies have begun to suggest that atopy, as conventionally defined, might be an umbrella term that obfuscates more specific allergic disease types. | 2014 | 24636082 |
| skin prick test reactivity to common aero and food allergens among children with allergy. | the prevalence of allergic diseases has risen in the last decades. the objective of this study was to determine the common allergens in children via the skin prick test. | 2014 | 24453391 |
| clearance of aspergillus fumigatus is impaired in the airway in allergic inflammation. | aspergillus fumigatus (af) sometimes colonizes and persists within the respiratory tree in some patients with asthma. to date, the precise reasons why the clearance of af is impaired in patients with asthma remain unknown. | 2014 | 24932688 |
| co-sensitization to silkworm moth (bombyx mori) and 9 inhalant allergens among allergic patients in guangzhou, southern china. | this study aimed to investigate the profile of sensitization to silkworm moth (bombyx mori) and other 9 common inhalant allergens among patients with allergic diseases in southern china. | 2014 | 24787549 |
| cloning, expression, and analysis of a cdna coding for the dermatophagoides farinae group 21 (der f 21) allergen. | domestic mite species like dermatophagoides farinae induce allergies in people worldwide. here, the cdna coding for group 21 allergen of dermatophagoides farinae (hughes; acari: pyroglyphidae) from china was cloned, sequenced, and expressed in e. coli to aid in the development of diagnostic and treatment options for domestic mite hypersensitivity. first, the der f 21 cdna fragment was synthesized by rt-pcr; the confirmed full-length sequence comprised 411 nucleotides. the cdna was ligated to the ... | 2014 | 25628789 |
| generation of a chimeric dust mite hypoallergen using dna shuffling for application in allergen-specific immunotherapy. | specific immunotherapy (sit) is the only treatment that provides long lasting relief of allergy symptoms. unfortunately, sit-based traditional remedies carry the risk of producing local and/or systemic side effects. to improve the safety and efficacy of sit, it has been proposed that sit must utilize allergens that are hypoallergenic but hyperimmunogenic. therefore, we used dna shuffling to generate mutant genes encoding hypoallergens with potent immunogenicity and screened them for their capaci ... | 2014 | 25120738 |
| expression, cloning, and ige-binding of the full-length dust mite allergen der f 8. | dermatophagoides farinae, a domestic mite species, produces some of the most potent allergens that contribute to allergy in china and worldwide. we sought to clone and express the group 8 allergen of d. farinae (der f 8) to investigate its ige-binding reactivity. the full-length cdna encoding der f 8 was generated by using rt-pcr and 5' race, cloned into pcold-tf expression vector, confirmed by nucleotide sequencing, sub-cloned into pet-28b (+), and transfected into e. coli bl21 cells for expres ... | 2014 | 24838264 |
| intestinal parasitic infections and atopic dermatitis among venezuelan warao amerindian pre- school children. | we evaluated the influence of intestinal parasitic infection on food sensitization associated to the severity of atopic dermatitis (ad) in a group of warao amerindian pre- school children. | 2014 | 24417507 |
| association of cytokines in individuals sensitive and insensitive to dust mites in a brazilian population. | allergic reaction to dust mites is a relatively common condition among children, triggering cutaneous and respiratory responses that have a great impact on the health of this population. anaphylactic hypersensitivity is characterized by an exacerbated response involving the production of regulatory cytokines responsible for stimulating the production of ige antibodies. | 2014 | 25238536 |
| component-resolved diagnosis (crd): is it worth it? frequency and differentiation in rhinitis patients with mite reactivity. | component-resolved diagnosis (crd) using microarray technology has recently been introduced with the aim to improve diagnosis of allergy. the aim of this study was to compare performance of this allergen microarray to those of an established extract-based skin prick testing (spt).45 patients with allergic rhinitis were studied (16 children and 29 adults). spt to dermatophagoides pteronyssinus, dermatophagoides farinae and blomia tropicalis extracts and allergen microarray immunocap isac were car ... | 2014 | 24659159 |
| the complete mitochondrial genome of the scab mite psoroptes cuniculi (arthropoda: arachnida) provides insights into acari phylogeny. | limited available sequence information has greatly impeded population genetics, phylogenetics and systematics studies in the subclass acari (mites and ticks). mitochondrial (mt) dna is well known to provide genetic markers for investigations in these areas, but complete mt genomic data have been lacking for many acari species. herein, we present the complete mt genome of the scab mite psoroptes cuniculi. | 2014 | 25052180 |
| the complete mitochondrial genome of the brown leg mite, aleuroglyphus ovatus (acari: sarcoptiformes): evaluation of largest non-coding region and unique trnas. | the circular mitochondrial genome (mitogenome) of aleuroglyphus ovatus was sequenced. it was 14,328 bp long, and consisted of 37 coding genes including 13 protein-coding genes, two ribosomal rna genes, and 22 transfer rna genes. this is the first description of the complete mitogenome of a species in the acaridae (acari: sarcoptiformes). the mtdna gene order for a. ovatus is identical to those of dermatophagoides farinae and d. pteronyssinus, but distinctly different from the mtdna of other acar ... | 2014 | 24777358 |
| mite hypersensitivity in patients with rhinitis and rhinosinusitis living in a tropical environment. | rhinitis and rhinosinusitis are major concerns in public health. mites are important aetiological agents in the tropics. the present study investigated the in vivo response to mite allergens in patients with rhinitis and rhinosinusitis. | 2014 | 23253681 |
| mite species identification in the production of allergenic extracts for clinical use and in environmental samples by ribosomal dna amplification. | the identification of allergy-causing mites is conventionally based on morphological characters. however, molecular taxonomy using ribosomal dna (rdna) may be particularly useful in the analysis of mite cultures and purified mite fractions in the production of allergenic extracts. full-length internal transcribed spacers (its1 and its2) were obtained from dermatophagoides farinae, dermatophagoides pteronyssinus, dermatophagoides microceras and euroglyphus maynei (astigmata: pyroglyphidae), glycy ... | 2014 | 24617319 |
| prevalence of and risk factors for increased serum levels of allergen-specific ige in a population of norwegian dogs. | the importance of different allergens in association with ige production and canine atopic dermatitis (cad) has been poorly studied and few studies exist on factors influencing allergen-specific ige antibodies in serum. the aim of this cross-sectional study was to investigate the prevalence of elevated ige levels to different environmental allergens in norwegian dogs with a suspicion of cad. the secondary aim was to identify risk factors associated with elevated serum levels of allergen-specific ... | 2014 | 25475748 |
| sensitivity to five types of house dust mite in a group of allergic egyptian children. | background: the published data on house dust mite (hdm) sensitization from egypt are scanty. we sought to investigate the sensitization to five different types of hdm among a group of allergic children in a trial to outline the most frequent sensitizing strains in the cairo province. methods: we consecutively enrolled 100 asthmatic patients, aged 1-7 years, of whom 22 had concomitant skin allergy. skin prick testing was performed using allergen extracts of dermatophagoides pteronyssinus, dermato ... | 2014 | 25276487 |
| equine intradermal test threshold concentrations for house dust mite and storage mite allergens and identification of stable acari fauna. | house dust mite (hdm) and storage mite (sm) stable fauna and their associated equine intradermal test (idt) threshold concentrations (tcs) for the midwestern region of the usa are unknown. | 2014 | 24800265 |
| ige reactivity to acarus siro extract in korean dust mite allergic patients. | although specific ige to the storage mite acarus siro is often detected, there are no detailed studies on ige reactivity to a. siro in korea. this study was undertaken to investigate the cross-reactivity to the mite species dermatophagoides pteronyssinus, dermatophagoides farinae, tyrophagus putrescentiae, and a. siro in korean mite allergic patients. specific ige values were determined for the four mite species and a competitive inhibition test was performed for mite extracts using the immunoca ... | 2014 | 24287899 |
| acaricidal activities of β-caryophyllene oxide and structural analogues derived from psidium cattleianum oil against house dust mites. | this study was to evaluate the acaricidal activities of an active compound isolated from psidium cattleianum and structural analogues against dermatophagoides farinae and d. pteronyssinus. β-caryophyllene oxide was isolated using chromatographic techniques. | 2014 | 23861316 |
| the gardenia jasminoides extract and its constituent, geniposide, elicit anti-allergic effects on atopic dermatitis by inhibiting histamine in vitro and in vivo. | gardenia jasminoides ellis has been used in traditional medicine for treatment of inflammation, edema, and dermaitis. the aim of this study was to investigate the mechanism by which gardenia jasminoides extract (gje) elicits anti-allergic effects in mast cells and in mice with atopic dermatitis (ad). | 2014 | 25153023 |
| a nationwide survey of inhalant allergens sensitization and levels of indoor major allergens in korea. | the higher prevalence of respiratory allergic disease may be due to increased exposure to inhalation allergens. we conducted a survey of allergic diseases in autumn and winter with detection of major indoor allergens in major cities in korea. | 2014 | 24843797 |
| variability of offending allergens of allergic rhinitis according to age: optimization of skin prick test allergens. | this study evaluates offending allergens in patients with allergic rhinitis (ar) according to age that establish a minimal panel for skin prick test (spt) allergens required to identify if a patient is sensitized. | 2014 | 24404393 |
| [analysis of allergen skin test results in 1124 patients with allergic rhinitis in the junction of guangdong and guangxi provinces]]. | to investigate the characteristics and influence factors of sensitization hy allergens in patients with allergic rhinitis in the junction of guangdong and guangxi provinces. | 2014 | 24826453 |
| sensitization profile to allergens in patients using multi-test ii. | introduction medical intervention in allergies has broadened its perspective, also focusing in the quality of life of patients. patients are instructed, before using pharmacotherapy agents, to avoid the causal agent. objective this study aims to analyze the sensitization profile of patients with allergic complaints and identify possible characteristics specific to each age group and gender. methods a descriptive cross-sectional study included data collected from medical records (from multi-test ... | 2014 | 25992129 |
| bartonella-like bacteria carried by domestic mite species. | bacteria of the genus bartonella are carried by haematophagous mites, ticks, fleas and flies, and attack the erythrocytes of mammals. here we describe a bartonella-like clade, a distinct group related to bartonellaceae, in stored-product mites (acari: astigmata) and a predatory mite cheyletus eruditus (acari: prostigmata) based on the analysis of cloned 16s rrna gene sequences. by using the clade-specific primers, closely related bartonella-like 16s rrna sequences were amplified from both labora ... | 2014 | 24711066 |
| clinical efficacy and compliance of sublingual immunotherapy with dermatophagoides farinae drops in patients with atopic dermatitis. | the oral route for administration of allergen immunotherapy has been explored since the 1900s. we attempted to evaluate the efficacy and safety of sublingual immunotherapy (slit) with dermatophagoides farinae drops in patients with atopic dermatitis (ad) and investigate related factors influencing the patients' compliance. | 2014 | 23968339 |
| acaricidal activities of bicyclic monoterpene ketones from artemisia iwayomogi against dermatophagoides spp. | the acaricidal properties of 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one isolated from artemisia iwayomogi and its structural analogues were evaluated against dermatophagoides farinae and d. pteronyssinus, and their effects were compared with that of the commercial acaricide benzyl benzoate. based on the 50 % lethal dose (ld50) values against d. farinae, 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (0.82 μg/cm(2)) was 9.71 times more effective than benzyl benzoate (7.96 μg/cm(2)), followed by (1r)-1, ... | 2014 | 24114336 |
| 20-o-β-d-glucopyranosyl-20(s)-protopanaxadiol-fortified ginseng extract attenuates the development of atopic dermatitis-like symptoms in nc/nga mice. | ginseng and ginsenosides are frequently used in the treatment of chronic inflammatory diseases. recently, 20-o-β-d-glucopyranosyl-20(s)-protopanaxadiol (gpd), the main metabolite of ginsenosides, was reported to have both anti-allergic and anti-pruritic effects. the immunomodulatory effects of gpd-fortified ginseng extract (gfge) on atopic dermatitis (ad)-like symptoms in mice were investigated. this study was designed to investigate the preventive effect of gfge on ad-like symptoms. | 2014 | 24269244 |
| time-dependent progression from the acute to chronic phases in atopic dermatitis induced by epicutaneous allergen stimulation in nc/nga mice. | atopic dermatitis (ad) is a complicated skin condition influenced by genetic background and environmental factors. in this study, we applied dermatophagoides farinae body extract (dfe) to the barrier-disrupted skin of nc/nga mice twice a week for 8 weeks to identify the clinical and immunological factors in ad progression. repeated application of the dfe to the skin of nc/nga mice showed the similar consequences for the natural course of progression in human ad, histologically and immunologicall ... | 2014 | 24299269 |
| effects of the recombinant allergen rder f 2 on neuro-endocrino-immune network in asthmatic mice. | severe and life-threatening side effects can occur in patients receiving allergen-specific immunotherapy (sit), and recombinant allergens made from cdna have been used in clinical trials for ten years and appear promising for sit. the aim of this study is to explore the effects of the recombinant allergen der f 2 (the group 2 allergen from dermatophagoides farinae) on the neuro-endocrino-immune network in asthmatic mice. twenty-eight mice were divided into four groups - a, b, c and d. to induce ... | 2014 | 26155138 |
| dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization. | the myeloid c-type lectin receptor dectin-2 directs the generation of th2 and th17 immune responses to the house dust mite dermatophagoides farinae through the generation of cysteinyl leukotrienes and proinflammatory cytokines, respectively, but a role for dectin-2 in effector phase responses has not been described. in this study, we demonstrate that administration of the dectin-2 mab solely at the time of d. farinae challenge abrogated eosinophilic and neutrophilic inflammation in the bronchoal ... | 2014 | 24453247 |
| toll-like receptors required for dermatophagoides farinae to activate nf-κb. | body and excrement extracts from dermatophagoides farinae were used to study stimulation of toll-like receptors (tlrs). the excrement extract stimulated nuclear factor (nf)-κb-dependent reporter activity to an extent similar to lipopolysaccharide (lps) in a mouse macrophage cell line, j774a.1, but the activity of the body extract was negligible. the excrement extract also activated nf-κb in hek293 cells expressing tlr1/tlr2, tlr2/tlr6 and cd14/tlr4/md-2, whereas no activation was observed in cel ... | 2014 | 24389483 |
| block copolymer/dna vaccination induces a strong allergen-specific local response in a mouse model of house dust mite asthma. | allergic asthma is caused by abnormal immunoreactivity against allergens such as house dust mites among which dermatophagoides farinae (der f) is a common species. currently, immunotherapy is based on allergen administration, which has variable effect from patient to patient and may cause serious side effects, principally the sustained risk of anaphylaxis. dna vaccination is a promising approach by triggering a specific immune response with reduced allergenicity. | 2014 | 24497934 |
| acaricidal activities against house dust mites of spearmint oil and its constituents. | the aim of this study was to evaluate the acaricidal activities of spearmint oil and carvone derivatives against house dust mites using contact and fumigant toxicity bioassays to replace benzyl benzoate as a synthetic acaricide. based on the ld50 values, the contact toxicity bioassay revealed that dihydrocarvone (0.95 and 0.88 µg/cm2) was 7.7 and 6.8 times more toxic than benzyl benzoate (7.33 and 6.01 µg/cm2) against dermatophagoides farinae and dermatophagoides pteronyssinus, respectively, fol ... | 2014 | 24488719 |
| the association between serum vitamin d level and immunoglobulin e in korean adolescents. | vitamin d has immune modulatory functions, and thus its relationship with allergic disease has been evaluated in a number of studies. however, no concrete link between serum ige level and vitamin d has been established. thus, the purpose of study was to confirm the association of serum vitamin d level with the serum ige (total and dematophagoides farinae specific ige) in korean adolescents. | 2014 | 24630983 |
| artemisia capillaris inhibits atopic dermatitis-like skin lesions in dermatophagoides farinae-sensitized nc/nga mice. | artemisia capillaries thunb. (ac) has been used to treat inflammatory and hepatic disorders such as hepatic injury, hepatic fibrosis and hepatitis. however, the efficacy of ac against atopic dermatitis (ad), an inflammatory disease, has not been examined. in the present study, ac was evaluated for anti-inflammatory and anti-ad effects using both in vitro and in vivo systems. | 2014 | 24624888 |
| evaluation of the acaricidal toxicities of camphor and its structural analogues against house dust mites by the impregnated fabric disc method. | the acaricidal activities of (±)-camphor structural analogues against house dust mites were evaluated using the impregnated fabric disc bioassay. | 2014 | 24616046 |
| effects of sublingual immunotherapy for dermatophagoides farinae on th17 cells and cd4(+) cd25(+) regulatory t cells in peripheral blood of children with allergic asthma. | sublingual immunotherapy is becoming a more common treatment for allergic diseases, particularly in pediatric clinics. this type of treatment is highly effective for dermatophagoides farinae allergy, but the mechanisms resulting in immune tolerance have not been investigated. we explored the effects of sublingual immunotherapy with d. farinae drops on populations of subsets of t immune cells, specifically th17 cells and cd4(+) cd25(+) regulatory t cells (treg cells), in peripheral blood of child ... | 2014 | 24591191 |
| the relationship between a specific ige level and asthma outcomes: results from the 2005-2006 national health and nutrition examination survey. | allergen exposure is associated with increased specific ige (sige), and allergen exposure plus sensitization is predictive of asthma outcomes. however, it is not known if sige is predictive of asthma outcomes in the absence of exposure data. | 2014 | 24565622 |
| cysteinyl leukotriene receptor antagonist regulates allergic airway inflammation in an organ- and cytokine-specific manner. | cysteinyl leukotrienes (cys-lts) are very important factors in the pathophysiology of bronchial asthma. cys-lt receptor antagonists (ltras) decrease allergic airway inflammation. the aim of the present study was to determine the differential effects of ltras and corticosteroids on allergic airway inflammation and allergen-specific cytokine production from lymphoid tissues using a murine model of asthma. | 2014 | 24561545 |
| high-intensity swimming exercise increases dust mite extract and 1-chloro-2,4-dinitrobenzene-derived atopic dermatitis in balb/c mice. | the aim of this study was to investigate the effect of high-intensity swimming exercise (hise) on atopic dermatitis (ad). for the study, we established an ad model in balb/c mice by repeated local exposure of house dust mite extract (dermatophagoides farinae extract, dfe) and 1-chloro-2,4-dinitrobenzene (cdnb) to the ears. after hise for 4 weeks, epidermal thickness, mast cell infiltration, serum immunoglobulin e (ige), and histamine were measured. in addition, the gene expression of interleukin ... | 2014 | 24526290 |
| toxicity of basil oil constituents and related compounds and the efficacy of spray formulations to dermatophagoides farinae (acari: pyroglyphidae). | pyroglyphid house dust mites are the most common cause of allergic symptoms in humans. an assessment was made of the toxicity of basil, ocimum basilicum l, essential oil, 11 basil oil constituents, seven structurally related compounds, and another 22 previously known basil oil constituents to adult american house dust mites, dermatophagoides farinae hughes. the efficacy of four experimental spray formulations containing basil oil (1, 2, 3, and 4% sprays) was also assessed. results were compared ... | 2014 | 24897858 |
| in silico prediction of t and b cell epitopes of der f 25 in dermatophagoides farinae. | the house dust mites are major sources of indoor allergens for humans, which induce asthma, rhinitis, dermatitis, and other allergic diseases. der f 25 is a triosephosphate isomerase, representing the major allergen identified in dermatophagoides farinae. the objective of this study was to predict the b and t cell epitopes of der f 25. in the present study, we analyzed the physiochemical properties, function motifs and domains, and structural-based detailed features of der f 25 and predicted the ... | 2014 | 24895543 |
| use of activity monitors for assessment of pruritus in an acute model of canine atopic dermatitis. | we developed a canine model of acute atopic dermatitis to evaluate the potential of compounds to treat pruritus and skin lesions induced in dermatophagoides farinae (df)-sensitized dogs. | 2014 | 24889924 |
| mite and booklouse fauna from vacuumed dust samples from beijing. | a significant-source of allergens come from house dust that contain particles derived from arthropods, molds, and pet dander. this study evaluated mite and booklouse fauna from vacuumed dust samples in beijing china (a temperate zone). our survey was carried out in beijing in the homes of mite allergic patients who visited our allergy department. in total, 38 homes were selected for the collection of dust samples by vacuuming, from december 2008 to january 2010. the flotation method was used to ... | 2014 | 24843802 |
| therapeutic effects of full spectrum light on the development of atopic dermatitis-like lesions in nc/nga mice. | full spectrum light (fsl) includes uva, visible light and infrared light. many studies have investigated the application of fsl in severe cases of atopic dermatitis (ad) in humans; however, fsl has not yet been studied in an animal model. the purpose of this study was to evaluate the therapeutic effects of fsl on ad-like skin lesions using nc/nga mice, with the aim of mitigating itching and attenuating the expression of adhesion molecules. we examined the effects of fsl on mite allergen-treated ... | 2014 | 24773136 |
| association study on adam33 polymorphisms in mite-sensitized persistent allergic rhinitis in a chinese population. | the adam33 gene has been identified as a potentially important asthma candidate gene and polymorphisms in this gene have been shown to be associated with asthma and seasonal allergic rhinitis. | 2014 | 24751681 |
| human placental extract reduces allergic inflammation in a murine allergic rhinitis model. | in this study, we addressed the immunotherapeutic potential of human placental extract (hpe) in a murine allergic rhinitis (ar) model and explored its immunological mechanisms. | 2014 | 24729028 |
| direct analysis of airborne mite allergen (der f1) in the residential atmosphere by chemifluorescent immunoassay using bioaerosol sampler. | dermatophagoides farinae allergen (der f1) is one of the most important indoor allergens associated with allergic diseases in humans. mite allergen der f1 is usually associated with particles of high molecular weight; thus, der f1 is generally present in settled dust. however, a small quantity of der f1 can be aerosolized and become an airborne component. until now, a reliable method of detecting airborne der f1 has not been developed. the aim of this study was to develop a fiber-optic chemifluo ... | 2014 | 24725888 |
| efficacy and safety of sublingual immunotherapy in children aged 3-13 years with allergic rhinitis. | sublingual immunotherapy (slit) is recommended for allergic diseases. however, clinical studies containing evidence-based data of this treatment in young children, which is rarely reported in the literature, are needed. this study was designed to assess the efficacy and safety of slit in children, including very young children. | 2014 | 24717951 |
| the effects of alcohol consumption and smoking on allergy risk in korean adults. | the immune-modulating effects of alcohol and smoking are well known through a great body of research. furthermore, many studies have been performed on the influence of alcohol and smoking on the development of allergic disease. however, previous studies have reported conflicting results with associations between alcohol intake or smoking and risk of allergy. the purpose of this study was to evaluate the effects of alcohol consumption and smoking on total serum immunoglobulin e (tige) and prevale ... | 2014 | 24717878 |
| antiatopic dermatitis effect of artemisia iwayomogi in dust mice extract-sensitized nc/nga mice. | aims. artemisia iwayomogi (ai) has been used for fever reduction, diuresis, and hepatoprotection in korea. the present study was performed to evaluate the anti-inflammatory and antiatopic dermatitis effects of ai using both in vitro and in vivo systems. methods. the compositions in ai were analyzed by hplc. to determine the anti-inflammatory effects of ai, the production of nitric oxide (no) was measured in lipopolysaccharide treated raw264.7 cells. histamine levels were assayed to evaluate the ... | 2014 | 24707309 |
| inhibitory effect of galangin on atopic dermatitis-like skin lesions. | galangin is a member of the flavonol class of flavonoids having anti-inflammatory and anti-oxidative potential. previously we reported the inhibitory effect of galangin on the mast cell-mediated allergic inflammation. for incremental research, we investigated the effects of galangin on atopic dermatitis (ad)-like skin lesions and underlying mechanisms of action. we established an atopic dermatitis model in balb/c mice by repeated local exposure of house dust mite (dermatophagoides farinae) extra ... | 2014 | 24675422 |
| regulation of constitutive neutrophil apoptosis due to house dust mite allergen in normal and allergic rhinitis subjects. | house dust mite (hdm) is a primary allergen in allergic rhinitis (ar) and asthma. neutrophil apoptosis is associated with allergic diseases and innate immunity to infection. the present study examined how hdm affects constitutive neutrophil apoptosis in normal and ar subjects. total ige increased in ar subjects when compared to normal subjects, and patients with ar were hdm-specific ige positive (+), which is specific ige to dermatophagoides pteronissinus and dermatophagoides farinae. in normal ... | 2014 | 25243400 |
| a multicenter study of the clinical features of allergic rhinitis in central china. | several epidemiological surveys of allergic rhinitis (ar) have been conducted in china. however, the clinical features of ar are still not clear enough. the aim of the current study was to perform a multicenter investigation to evaluate the clinical features of ar in china. | 2014 | 25198025 |
| house dust mite allergen levels in households and correlation with allergic rhinitis symptoms. | house dust mite (hdm) allergen is a risk factor for the development of allergic rhinitis (ar). | 2014 | 25198017 |
| design of a proder f 1 vaccine delivered by the mhc class ii pathway of antigen presentation and analysis of the effectiveness for specific immunotherapy. | dermatophagoides farinae (der f 1) is one of leading cause for allergic asthma, and allergen-specific immunotherapy (sit) is currently recognized as the only etiological therapy to ameliorate asthmatic symptom. the current study was designed on the major histocompatibility complex (mhc) class ii pathway, invariant chain (ii)-segment hybrids as vaccine basis to explore the efficacy of der f 1 hybrid vaccine by virtue of ii as carrier in enhancing the protective immune response to asthma. initiall ... | 2014 | 25197336 |
| progress in the development of specific immunotherapies for house dust mite allergies. | allergen-specific immunotherapy is used to treat patients exposed and co-sensitized to the two common house dust mites, dermatophagoides pteronyssinus and dermatophagoides farinae. based on seroepidemiological studies and a detailed characterization of mite allergens, an optimal immunotherapeutic product should associate extracts from the two dermatophagoides species, and include both bodies and fecal particles. both subcutaneous and sublingual immunotherapies performed with aqueous mite extract ... | 2014 | 25187166 |