Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| susceptibility of the anaerobic bacteria, group d streptococci, enterobacteriaceae, and pseudomonas to semisynthetic penicillins: carbenicillin, piperacillin, and ticarcillin. | sodium piperacillin t-1220, a new semisynthetic penicillin, was tested in vitro against 297 clinical isolates of anaerobic bacteria and 669 aerobic bacteria by the conventional agar dilution method and compared with carbenicillin and ticarcillin. at a 100-mug/ml concentration the three drugs showed comparable effectiveness against the anaerobes tested. however, at 20 mug/ml, piperacillin was the most effective drug against bacteroides fragilis, peptostreptococci, and group d streptococci. at thi ... | 1978 | 103491 |
| the effect of l-serine, dl-tryptophan and l-glutamic acid on either form of catalase in guinea pig liver. | 1978 | 104908 | |
| [distribution of the rabies virus in the central nervous system of naturally infected foxes]. | quantitative distribution of rabies virus and the character of immunofluorescence in various parts of the central nervous system [cns] and salivary glands were investigated in 21 naturally infected foxes. a mean death period was recorded in mice infected with the virus obtained from various parts of the cns and salivary glands of the investigated foxes. the highest average titer of the virus was found out in the salivary glands - 4.46 log mld50 per 0.03 ml i. c. the average titer was 2.30 log in ... | 1978 | 97842 |
| a human studying the sensing of chemicals by bacteria. | a new frame of reference, which in its fundamental structuring differs radically from the structuring of the familiar western indo-european viewpoints (logical, mathematical, scientific, philosophical, etc.), already exists. recently, by the strategem of systematically disallowing a previously unnoticed untenable assumption encoded in the traditional western symbolic logics, set theories, etc., in particular and in the western 'world-view' in general, this frame of reference has generated its ow ... | 1978 | 97887 |
| factors for poor prognosis in fulminating meningococcemia. conclusions from observations of 67 childhood cases. | 1978 | 98253 | |
| [clinical and electrophysiological aspects of the gangliosidoses (author's transl)]. | the gangliosidoses belong to the family of diseases known as the lipidoses and are due to an excess of ganglioside i (gm1) or ii (gm2). the illness described by landing belongs to group i, whilst tay-sachs and sandhoff's disease are type 2. this study was particularly concerned with the electro-clinical aspects of group 2, and 4 stages have been differentiated: --the first occurs between 4-10 months: the child is apathetic, hypotonic and has occasional audiogenic seizures; fundoscopy revealing t ... | 1978 | 96499 |
| [cytoarchitectonics of ileocecal lymph nodes in newborn and sexually mature simians (pavian hamadrils)]. | cell composition of various components (cortical plateau, folliculi and cords) of ileocecal lymph nodes was studied in newborn, 1.5 and 2.5 months of age (2 animals) and in mature (3 animals) monkeys, papio hamadryas. in histological sections obtained at the level of hilus of the lymph node cellular elements were counted by means of morphometric grid of glagolev modifoed by s. b. stefanov. the data obtained were statistically treated. newborn and mature monkeys have their peculiar cytological pr ... | 1978 | 98135 |
| positive regulation of amidase synthesis in pseudomonas aeruginosa. | mutants of pseudomonas aeruginosa were isolated that were acetamide-negative in growth phenotype at 41 degrees c and constitutive for amidase synthesis at 28 degrees c. two mutants were derived from the magno-constitutive amidase mutant pac111 (c11), and a third from a mutant that had enhanced inducibility by formamide, pac153 (f6). the three temperature-sensitive mutants produced amidases with the same thermal stabilities as the wild-type enzyme. cultures growing exponentially at 28 degrees c, ... | 1978 | 98516 |
| quantitative determination of the serum antibody response to the capsular polysaccharide of bacteroides fragilis subspecies fragilis in women with pelvic inflammatory disease. | the antibody response to the capsular polysaccharide of bacteroides fragilis subspecies fragilis in women with acute pelvic inflammatory disease was quantitated using a sensitive radioactive antigen-binding assay. antibody detected by this technique correlated highly with antibody measured by quantitative precipitin analysis (r = 0.99). paired acute- and convalescent-phase sera obtained from women from whom b. fragilis subspecies fragilis was isolated by culdocentesis showed significantly greate ... | 1978 | 98597 |
| passage of immunoglobulins from plasma to the oral cavity in rhesus monkeys. | the passage of immunoglobulin from plasma to the oral cavity was studied in rhesus monkeys. immunoglobulins g, a and m were purified from pooled rhesus monkey serum, radiolabelled with 125i and injected intravenously into twelve monkeys. sequential samples of oral fluids were taken over a 24 h period and were assayed for radioactivity. radioactivity could be detected in crevicular fluid washings after 0.5 h in monkeys injected with igg and iga, and after 2 h in monkeys given igm. maximal levels ... | 1978 | 104924 |
| prostaglandin synthetase dependent activation of 7,8-dihydro-7,8-dihydroxy-geno (a) pyrene to mutagenic derivativies. | 1978 | 96834 | |
| a new sequence-specific endonuclease from anabaena cylindrica. | 1978 | 103749 | |
| influence of type of antibiotic and length of antibiotic feeding period on performance and persistence of antibiotic resistant enteric bacteria in growing-finishing swine. | 1978 | 97254 | |
| age-associated changes in the blood picture of the goat. | 1978 | 98936 | |
| improved safety of splenoportography by plugging of the needle tract. | splenoportography, a useful preoperative diagnostic procedure in patients with portal hypertension, has been largely discontinued because of the risk of hemorrhage. we have used both ivalon and gelfoam in particle and plug form to plug the needle tract after splenoportography. initial studies were conducted on six dogs. plugging of the needle tract by injection of suspensions of small gelfoam or ivalon particles resulted in intravasation of these particles into the splenic vein. this was demonst ... | 1978 | 98987 |
| rabbit polymorphonuclear leukocyte chemotactic factor generated in vivo by bacteroides fragilis lipopolysaccharide. ii. antigenic and biologic properties. | preparations of the polymorphonuclear leukocyte (pmn) chemotactic factor isolated from lipopolysaccharide (lps)-induced inflammatory exudate in rabbits were immunogenic in guinea pigs. complete fusion of the precipitation lines produced against anti-cf by lps-cf (molecular weigth 16,000) and material eluted on sephadex g-200 columns with molecular weights (mw) of 68,000, 16,000 and 7,000 was found. also, the chemotactically active material with mw of 68,000 and 7,000 eluted on g-75 columns after ... | 1978 | 99978 |
| ultraviolet light-induction and photoreactivation of thymine dimers in a cyanobacterium, anacystis nidulans. | partially photoreactivable mutant of anacystis nidulans demonstrates partial photorepair of thymine dimers. the wild type which is completely photoreactivable at the conditions studied shows higher level of thymine dimer photolysis. | 1978 | 100072 |
| synchronous, sustained oscillation of c-peptide and insulin in the plasma of fasting monkeys. | the previously reported synchronous oscillations in plasma glucose and insulin levels have been further studied to determine whether the phenomenon can be attributed to cyclic secretion or degradation of the hormone. plasma c-peptide concentrations were measured and found to cycle with the same period as plasma insulin suggesting that the oscillations of insulin arise from changing secretion rather than degradation. the amplitude of c-peptide oscillation was 50 percent that of insulin. assuming ... | 1978 | 105880 |
| purification and some properties of porcine brain mitochondrial monoamine oxidase b. | 1978 | 103556 | |
| insulin counteraction of alpha-adrenergic effects on liver glycogen metabolism. | insulin counteracted the effects of a pure alpha-adrenergic agonist, phenylephrine, on hepatocyte glycogen synthase and phosphorylase. these results argue against current concepts of insulin increasing cytoplasmic ca2+ concentration. | 1978 | 103580 |
| thyroxine inactivation by starvation in cultured hepatocarcinoma cells, formation of reverse triiodothyronine. | the effect of starvation on thyroid hormone metabolism was studied in monkey hepatocarcinoma monolayer cultures. nonphenolic ring monodeiodination of thyroxine, 3, 5, 3'-triiodothyronine and 3, 3'-diiodothyronine was accelerated. since phenolic ring deiodination of 3, 3',5'-triiodothyronine (reverse t3) was unaffected, this metabolite accumulated in the medium during thyroxine metabolism. this suggests that increased serum reverse t3 in malnourished humans may be caused by enhanced deiodination ... | 1978 | 105981 |
| anti-kappa/lambda immunobead for detection of human b lymphocytes. | several methods were compared for quantitating the b lymphocytes in human peripheral blood. rbc rosette assays including sheep and bovine red blood cells, and immunobead rosette assays including beads coated with anti-kappalambda and trivalent anti-gam antibodies respectively were investigated. the anti-kappalambda bead assay proved to be simpler, faster, higher in reproducibility, and appeared to be more accurate than any of the other assays. | 1978 | 105987 |
| construction of a recombinant plasmid composed of b. subtilis leucine genes and a b. subtilis (natto) plasmid: its use as cloning vehicle in b. subtilis 168. | 1978 | 105237 | |
| ascorbic acid and drug metabolism in cynomologus monkeys. | 1978 | 99749 | |
| assessment of wound contamination by wound irrigation. experimental investigations on quantitative recovery of anaerobic and aerobic bacteria. | the quantitative recovery of e. coli, s. faecalis and b. fragilis from operative abdominal wounds was investigated in pigs in an experimental model suitable for statistical calculations. wounds were contaminated in groups of ten with different numbers of either a single bacterial species or a mixture of two species. the wound was irrigated with saline 20 minutes after contamination. significant differences in recovery were found between the bacterial species investigated. expressed as percentage ... | 1978 | 99976 |
| [effect of polychlorinated biphenyls in the rat: ii.--preliminary report on metabolic alterations (author's transl)]. | rats were fed with a diet containing 10 and 100 ppm (wet weight) of phenoclor dpr for 4 weeks in order to evaluate the toxicity of a french pcb mixture. the influence of pcb was studied by determining the liver weights, the hepatic and muscular proteins, glycogen and humidity content as well as hematocrite, glucose, proteins and lipids in the plasma, and the lipidic contents of the liver and the carcass. there was a significant increase in both liver to body weight ratios and liver lipid and pro ... | 1978 | 105425 |
| electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey. | 1978 | 98733 | |
| [some aspects relating to the aflatoxin generation during the self-heating of cereals]. | in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ... | 1978 | 98933 |
| comparison of antigens of pneumonia-associated mycoplasma species by gel diffusion. | comparison of fluorocarbon-extracted antigens of six mycoplasma species by double immunodiffusion and counterimmunodiffusion techniques revealed a close reciprocal relationship among mycoplasma dispar, m. ovipneumoniae, and m. hyopneumoniae. a lesser degree of cross-reaction was also demonstrated between these three species and m. hyorhinis and m. bovoculi. the interrelationships were more clearly demonstrated by double immunodiffusion than by counterimmunodiffusion. | 1978 | 101469 |
| [volatile fatty acids in gastrointestinal diseases in young infants]. | 1978 | 101958 | |
| comparison of the in vitro activity of bay k 4999 and piperacillin, two new antipseudomonal broad-spectrum penicillins, with other beta-lactam drugs. | bay k 4999 and piperacillin, two new substituted ampicillins, were compared with other beta-lactam antibiotics, including carbenicillin, azlocillin, mezlocillin, benzylpenicillin, ampicillin, and cefoxitin, against a wide range of gram-positive and -negative organisms. bay k 4999 and piperacillin were extremely active against pseudomonas aeruginosa (50% inhibited by 2 mug/ml), being about 16-fold more active than carbenicillin. bay k 4999 was the most active drug against escherichia coli (50% in ... | 1978 | 102245 |
| polychlorinated biphenyls induced rat liver adenomas. | multiple liver adenomas were found in 30 month old female rats which had received for 28 months, 200 ppm polychlorinated biphenyls (arochlor 1254) in their drinking water. no lung metastases were detected. the examination of fragments of these adenomas under the electron microscope showed group polymorphism of the hyperplastic liver cells. the ultrastructural changes were considered to be as a result of chemical lesions induced by polychlorinated biphenyls and as adaptive morphological responses ... | 1978 | 105426 |
| characterization and genetic control of the immune response to synthetic polypeptide antigens of defined geometry. | both humoral and cell-mediated immune responses to the synthetic helical hapten-carrier conjugate poly-glu-tyr-lys(tnp)-(glu-tyr-ala)5 were found to be linked to the major histocompatibility locus in mice and guinea pigs. the responder mouse strains (h-2d haplotype) showed a primary igm response with an igg component appearing after the secondary immunization. the antibody response was accompanied by a positive dth reaction in responder strains. nonresponder mice (h-2b or h-2k haplotypes) showed ... | 1978 | 98587 |
| control of cell multiplication: preparation and immunological comparison of inhibitory factors in the homogenate and perfusate of the adult rat liver. | the control of organ cell multiplication by a negative feed-back mechanism implies that factors of the inhibitory mechanism are present in the blood and are produced by the target organ itself. we have examined the inhibitors which are present in the cytosol of adult rat liver as well as in efferent fluid from an isolated perfused organ. these two materials yielded predominantly protein molecules having in common a molecular weight of approximately 80 000 daltons and an isoelectric point between ... | 1978 | 100149 |
| suppression of uterine motor activity by prostaglandin synthetase inhibitor naproxen. | rats were ovariectomized on day 16 of pregnancy and they were fitted with a pressure sensor uterine microballoon assembly and were given a daily dose of naproxen-sodium. daily uterine activity recordings were taken and subjected to statistical analysis and the rats were carefully checked for either aborting or delivering their fetuses. our data showed that naproxen treatment effectively and significantly prevented the autocatalytic evolution of the uterine motor activity and the regulatory "see- ... | 1978 | 105529 |
| macaca assamensis as a new host for experimental plasmodium knowlesi infection. | 1978 | 108217 | |
| limitations of aeruginocine typing of ps. aeruginosa as an epidemiological marker. | 1978 | 108218 | |
| transport of oligomeric iga of systemic origin into external secretions. | 1978 | 105568 | |
| case report: intestinal clearance of calcium and protein in waldenstrom's macroglobulinemia. | a 63-year-old man with waldenstrom's macroglobulinemia had severe steatorrhea, marked protein-losing enteropathy, and excessive endogenous fecal calcium clearance. the malabsorption and protein loss resulted in weight loss and hypoalbuminemia. in contrast, the striking enteric calcium loss was completely compensated by an increase in calcium absorption resulting in a positive calcium balance. | 1978 | 105640 |
| [changes in certain biochemical parameters of rat skin following prolonged gamma irradiation after radioprotection]. | 1978 | 106409 | |
| [evolution and transformation in animal organism of some polychlorobiphenyls (author's transl)]. | intoxication by pure polychlorobiphenyls and a commercial product is studied, in rats, after intraperitoneal and oral administration. their fixation and excretion of their metabolites is greater by intraperitoneal than by oral administration. the only hydroxy metabolites, identified by means of synthesis, gas chromatography and mass spectrometry are, all, derivatives from trichlorobiphenyl. it appears that administration of commercial product induces a more rapid degradation of these compounds i ... | 1978 | 105430 |
| tk polyagglutination associated with reduced a and h activity. | tk polyagglutinable erythrocytes are described in which a and h activities were reduced. it is suggested that bacteroides fragilis isolated from cultures of the patient's blood was responsible for each of these membrane modifications. | 1978 | 106548 |
| the effect of treatment with a polychlorinated-biphenyl mixture on hepatic and extrahepatic xenobiotic metabolism in the rat and ferret [proceedings]. | 1978 | 105952 | |
| [epileptogenic action of intra-amygdaloid injection of kainic acid]. | intra-amygdaloid unilateral application of low doses of kainic acid rapidly elicits, in both chronic and acute conditions, secondarily generalized convulsive seizures which often culminate in fatal true status epilepticus unless appropriate anti-epileptic drugs are provided. spontaneous recurrent seizures are observed for several hours starting approximately 10 min. after the application of kainic acid. in addition to the primary degeneration in the amygdaloid complex, a secondary cell loss is s ... | 1978 | 103652 |
| [nuclei of the mammillary bodies and their fiber connections in cattle (bos taurus var. domesticus). i. nuclei of the mammillary bodies in cattle]. | 1. in the present neuroanatomic study the topography and cytoarchitectonic of the nuclei of the mamillary body of cattle are described and quantitative-morphologically investigated in 14 series of brains (6 frontal, 4 sagittal and 4 horizontal series, stained by the methods after nissl, klüver and barrera and after heidenhain). 2. the medial mamillary nucleus of cattle is with an average volume of 47.7 mm3 the largest nucleus of the mamillary body. it contains about 715,000 cells with a cell den ... | 1978 | 107664 |
| [kinetics of the serological response in the experimental primary hydatid disease of mice infected with echinococcus granulosus embryophores (author's transl)]. | a serological response kinetics study was carried out in cf-1 mice orally infected with echinococcus granulosus embryophores using immuno-electrophoresis, double diffusion, latex agglutination and passive hemagglutination. starting from the 76th day after the infection, serum antibodies reach the minimum detectable level by immunoelectrophoresis test. band number 5, now considered as specific for e. granulosus, was proved to be the first precipitating system exhibited in this test. double diffus ... | 1978 | 105664 |
| [new species of obligate-thermophilic bacteria of the flavobacterium thermophilum type]. | 1978 | 154607 | |
| hydrolase activities in the rat aorta. i. effects of diabetes mellitus and insulin treatment. | vascular disease in diabetics could arise in part from altered vessel wall catebolism. specific activities of hydrolases in aortic smooth muscle cells from rats with streptozotocin-induced diabetes were measured. enyzmes included: neutral alpha-glucosidase, alpha-mannosidase, and lysosomal n-acetyl beta-glucosaminidase, beta-galactosidase, cathepsin c, acid alpha-glucosidase, and acid cholesteryl esterase. after 4,8, and 11 weeks of diabetes, activities of all enzymes studied were decreased sign ... | 1978 | 148980 |
| thermostable antigens from the bone marrow of several animal species. | studies on bone marrow extracts from ten animal species have revealed the presence of thermostable antigens. similar antigens were found in other organs as shown by immunodiffusion and cross-reactivity was demonstrated between the thermostable proteins from horse and dog and between cow and sheep proteins. using an immunoenzymatic reaction with glucose oxidase as the marker, the thermostable antigens were localized in the blood and bone marrow polymorphonuclear leukocytes and the myeloid cell li ... | 1978 | 105786 |
| serologic typing of rickettsiae of the spotted fever group by microimmunofluorescence. | 1978 | 101593 | |
| in vitro study of clavulanic acid in combination with penicillin, amoxycillin, and carbenicillin. | the activity of clavulanic acid alone and in combination with penicillin, amoxycillin, and carbenicillin was studied. marked reductions in the minimum inhibitory concentrations (mics) for a wide spectrum of beta-lactamase-producing clinical isolates were found. of particular interest were the decreased mics of penicillin for bacteroides fragilis and beta-lactamase-producing strains of neisseria gonorrhoea in the presence of the clavulanic acid. beta-lactamase-producing strains of escherichia col ... | 1978 | 122520 |
| effect of infrequent feeding and increased physical activity on cholesterol kinetics in the rat. | the authors studied the effect of chronic physical exercise (running in a rotating drum at 850 m/hour, 5 times a week for 16 weeks) on the size of the cholesterol body pools and on cholesterol kinetics in adult male wistar rats fed on a standard diet either ad libitum or 2 hours daily [33 weeks]. these data were obtained by mathematical analysis of the curve expressing the correlation of specific plasma cholesterol activity to time after a single dose of cholesterol-4-14c. chronic physical stres ... | 1978 | 149317 |
| siderophore production by vibrio cholerae. | vibrio cholerae produces a phenolate-type siderophore that stimulates growth of the organism in low-iron medium. this compound is similar, but not identical, to enterochelin, the siderophore produced by salmonella and escherichia coli. | 1978 | 149768 |
| piperacillin, a new penicillin active against many bacteria resistant to other penicillins. | the in vitro activity of piperacillin, a new semisynthetic piperazine penicillin derivative, was evaluated against 626 clinical isolates and compared with the activity of other beta-lactam antibiotics. at a concentration of 0.1 microgram/ml, piperacillin inhibited all streptococci except enterococci. non-beta-lactamase-producing staphylococci were inhibited by 1.6 microgram or less per ml. both beta-lactamase- and non-beta-lactamase-producing haemophilus were inhibited by 0.1 microgram/ml. piper ... | 1978 | 122519 |
| [effects of 5-hydroxytryptamine creatinine sulfate on development of the in vitro cultivated explants of the cerebrocortex of neonatal rats (author's transl)]. | explants of the cerebrocortex of neonatal rats were cultivated up to 15 div in addition to 5-hydroxytryptamine creatinine sulfate at the final concentration of 0.1 mm. fluorescence histochemical investigations were accomplished with a modified glyoxylic acid "heat reaction" according to lindvall and björklund (1974). depending on the duration of the cultivation and/or influence of the 5-hydroxytryptamine creatinine sulfate in varied fiber and cell elements of the explants varied effects were fou ... | 1978 | 105555 |
| [the immunhistochemical investigation of trypsin and trypsin-like-activity in the small intestine, pancreas and isolated langerhans islets. a light-, fluorescent- and electron microscopic study (author's transl)]. | by means of the indirect immunofluorescence and immunenzyme technique trypsin and trypsin-like activity in fixed cryostate sections of pancreas and gut and pellets of isolated pancreatic islets respectively were investigated using specific antiserum against trypsin. the enzyme was demonstrated in the cytoplasma of the acinus cells, the epithel cell of the intercalated ducts and the excretory (interlobular) ducts of the exocrine pancreas. by light and fluorescence microscopy we could also localiz ... | 1978 | 105556 |
| relationship between biotin-binding proteins from chicken plasma and egg yolk. | the plasma of laying hens contains a specific biotin-binding protein that appears to be identical with an egg-yolk biotin-binding protein. both proteins are saturated with biotin and require elevated temperatures to effect the exchange of [14c]biotin for the protein-bound vitamin. the heat-exchange curve in each case is the same and differs sharply from that of avidin, the egg-white biotin-binding protein. on sephadex g-100 gel filtration, plasma and yolk biotin-binding proteins were each eluted ... | 1978 | 105724 |
| purification and properties of beta-lactamase from bacteroides fragilis. | beta-lactamase activity was detected either biologically or using the chromogenic cephalosporin 87/312 in 20 clinical isolates of bacteroides fragilis with penicillin g minimal inhibitory concentrations of 10 to 100 micrograms/ml. strain am78 (minimal inhibitory concentration, greater than 1,000 micrograms/ml) was used to optimize the conditions for production, assay, and storage of the enzyme. the enzymes are cell associated, with less than 1% of activity being found in culture fluids during gr ... | 1978 | 45494 |
| pseudomembranous colitis. | 1978 | 77373 | |
| metronidazole in the prophylaxis and treatment of anaerobic infection. | the influence of prophylactic metronidazole on vaginal carriage rates of anaerobes and the development of postoperative anaerobic infection was studied in 104 women who underwent abdominal hysterectomy. metronidazole prophylaxis in 54 patients led to a decrease in the anaerobe vaginal carriage rate from 65% pre-operatively to 17% and 28% on the 3rd and 7th postoperative days respectively. in the control group (50 patients) no significant decrease in anaerobe yield was noted, corresponding percen ... | 1978 | 33454 |
| study of the glycolipid composition of the milk fat-globule membrane and the mouse mammary tumour virus prepared from the milk of infected swiss mice [proceedings]. | 1978 | 84579 | |
| quantitative evaluation of three commercial blood culture media for growth of anaerobic organisms. | the ability of three different commercial blood culture media--brain heart infusion broth (pfizer), thiol broth (difco), and prs-peptone broth (becton, dickinson & co.)--to support the growth of five different anaerobes is described. inocula of 100 and 1,000 colony-forming units per ml were used to evaluate potential differences in survival, lag time, growth rate, and doubling times of each anaerobe in each medium. in addition, each medium was evaluated for its ability to neutralize the antibact ... | 1978 | 24059 |
| chloramphenicol acetyltransferase of bacteroides fragilis. | chloramphenicol-resistant strains of bacteroides fragilis (minimum inhibitory concentration, 12.5 mug/ml) were isolated from a stool specimen which contained multiply resistant escherichia coli. the enzyme responsible for resistance, chloramphenicol acetyltransferase, was produced constitutively by these strains; the specific activity was 10-fold lower than that of the e. coli enzymes. similar activity was not detected in susceptible b. fragilis strains, nor could it be induced by growth in the ... | 1978 | 28690 |
| bacteroides fragilis resistant to metronidazole after long-term therapy. | 1978 | 74641 | |
| pleuropulmonary lung infection by anaerobic bacteria. | two patients with severe pleuropulmonary infection caused by non-sporing anaerobic bacteria are described. one had an empyema with foul-smelling pus and developed bacteraemia, and the other developed a lung abscess. both were successfully treated with antibiotics and drainage, chest surgery being avoided. the successful diagnosis and treatment of these patients involved close liaison between clinical and laboratory staff. | 1978 | 29654 |
| beta-lactamases in bacteroides. | bacteroides fragilis is responsible for most anaerobic infections in man. most isolates of b. fragilis show resistance to beta-lactam antibiotics. this resistance might be due to beta-lactamase production or permeability barrier in the cell wall. b. fragilis produce beta-lactamase with mainly cephalosporinase activity. other bacteroides species such as b. clostridiformis, b. melaninogenicus and b. oralis also produce beta-lactamase but with different biochemical characteristics. | 1978 | 28561 |
| characterization of receptors mediating 5-hydroxytryptamine- and catecholamine-induced platelet aggregation, assessed by the actions of alpha- and beta-blockers, butyrophenones, 5-ht antagonists and chlorpromazine. | 1 blood platelets from normal human volunteers were isolated and aggregated in vitro with 5-hydroxytryptamine (5-ht), noradrenaline (na), dopamine and n-dimethyldopamine (dmda). 2 the effects of 5-ht antagonists, alpha- and beta-adrenoceptor blocking agents, butyrophenones and chlorpromazine upon aggregation induced by the four amines were investigated. 3 only the the 5-ht antagonists, chlorpromazine and spiroperidol were potent inhibitors of 5-ht-induced aggregation, and only phentolamine was a ... | 1978 | 26445 |
| the bactericidal activity of nitrofurantoin and metronidazole against anaerobic bacteria. | 1978 | 25874 | |
| [intratypical antigenic differentiation of poliovirus strains circulating in mali by means of cross-adsorbed sera]. | the intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in mali in 1975-1976 was performed. the method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. all the examined strains of serologic types i, ii, and iii were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". quantitative differences in the ant ... | 1978 | 86237 |
| the use of trypan blue for counterstaining in the sepharose bead immunofluorescence test. the application of the test for the demonstration of primate retrovirus-specific antibodies and antigens. | the sepharose bead immunoflurorescence test was performed by counterstaining the beads with trypan blue. this results in a red staining of negative beads which allows an easy distinction from positive green-fluorescent beads. sepharose beads conjugated with viral proteins or antiviral antibodies were used to demonstrate mason-pfizer monkey virus (mpmw)- and simian sarcoma virus (ssv) - specific antigens or antibodies. the test shows a high sensitivity and specificity and needs a small amount of ... | 1978 | 86253 |
| [antibiotic treatment in acute peritonitis]. | the selection depends on several factors and in particular: -the means of transport by which the antibiotic reaches the peritoneum : the aminosides and the betalactamines attain the peritoneum easily while the polymyxins do not; -the causative agent: most often it is a gram negative aerobic or anaerobic bacteria. the entero-bacteria predominate but in the last few years bacteroides fragilis has been frequently encountered giving rise to numerous studies. the flora is most often polymicrobic. th ... | 1978 | 35071 |
| [bacteriological studies of peritonitis]. | bacterial infections of the peritoneum may be primary (pneumococcal peritonitis of childhood). these are rare, as are streptococcal and staphylococcal peritonitis in the neonate, following umbilical or tegumental infections. the great majority of cases of peritonitis are secondary to an adjacent inflammation, a perforation of the gastro-intestinal tract, or trauma, which may be surgical in origin. the microbial flora involved is generally mixed, with a high proportion of anaerobic organisms, ref ... | 1978 | 35067 |
| cefoxitin sodium activity against anaerobes: effect of the inoculum size, ph variation and different culture media. | 1978 | 29027 | |
| formation of glycosidases in batch and continuous culture of bacteroides fragilis. | nine strains of bacteroides fragilis were cultivated in stirred fermentors and tested for their ability to produce glycosidases. b. fragilis subsp. vulgatus b70 was used for optimizing the production of glycosidases. the highest bacterial yield was obtained in proteose peptone-yeast extract medium. the optimum ph for maximal bacterial yield was 7.0, and the optimum temperature for growth was 37 degrees c. the formation of glycosidases was optimal between ph 6.5 and 7.5, and the optimum temperatu ... | 1978 | 25044 |
| [alterations in pharmacokinetics during toxicity tests (author's transl)]. | some possible reasons are discussed which may lead to changes in the pharmacokinetics of a drug during long-term toxicity tests. since most of these alterations have toxicological consequences, their evaluation can be helpful in the interpretation of toxicity studies. furthermore, and altered pharmacokinetic profile may be a diagnostic tool for the detection of organ damage (e.g., eliminatory organs). in this paper three examples of the "radioactive test dose method" are shown. this method allow ... | 1978 | 89849 |
| 4th international workshop on human gene mapping. report of the committee on the genetic constitution of the x and y chromosomes. | 1978 | 88299 | |
| [perichordal necroses. contribution to the understanding of the spinal column morphogenesis]. | in 12--15 days old rat embryos and 12 days old mouse embryos vitally stained by acridin orange, a perichordal necrosis appears, showing metameric intensifications at the level of the dense sclerotomites. similar aspects were detected in serially sectioned rabbit and human embryos (6--7 mm c.r. length). the authors correlate the necrotic zones mentioned with the inductive functions of the notochord. | 1978 | 86154 |
| metronidazole resistance among bacteroides fragilis. | 1978 | 76262 | |
| chemotherapy of brain abscess. | 1978 | 82092 | |
| bowel preparation for surgery. | 1978 | 82688 | |
| a case of atypical polyagglutinability due to tk-transformation. | a case of acquired transient polyagglutinability in a group o, rh(d) positive female patient, wa, is described. an unusual finding in the preliminary serological investigation was the non-reaction of the cells with peanut (arachis hypogaea) extract. the patient's red cells were strongly agglutinated by normal human and rabbit sera from which anti-t had been removed. electrophoretic mobility studies and tests with polybrene indicated that their sialic acid content was normal. the use of a specifi ... | 1978 | 83151 |
| relationship of intracellular 3',5'-adenosine monophosphate accumulation to parathyroid hormone release from dispersed bovine parathyroid cells. | 1978 | 85548 | |
| observations concerning the staining properties of the macroconidia of certain dermatophyton species. | staining of the macroconidia of several dermatophyton species by lactophenol-cotton blue was investigated. young macroconidia stain variably; their cytoplasm may appear homogeneous or inhomogeneous. the possible explanation seems to be variation in the composition of the cytoplasm. in some macroconidia dark-staining filament was seen along the longitudinal axis. mature macroconidia showed basal or basal+apical homogeneous deep staining. the intensive apical staining suggests that the apical stru ... | 1978 | 89788 |
| chronotropic response of isolated atria to acid base alterations. | the effect of acid-base alterations on spontaneous rate was analysed using isolated atria exposed to cumulative degrees of acidosis produced either by adding hcl or by increasing pco2 in the incubation medium. frequncy vs. ph curves were made to assess chronotropic response to acid-base changes. heart rate was increased in alkalosis and decreased when the ph of the medium was lowered. both "respiratory" and "metabolic" alterations affected the contraction rate to the same extent. decreasing ph f ... | 1978 | 87182 |
| liver microsomal cytochromes p-450 and azoreductase activity. | hepatic microsomal azoreductase activity with amaranth (3-hydroxy-4[(4-sulfo-1-naphthalenyl)azo]-2,7-naphthalenedisulfonic acid trisodium salt) as a substrate is proportional to the levels of microsomal cytochrome p-450 from control or phenobarbital-pretreated rats and mice or cytochrome p-448 from 3-methylchol-anthrene-pretreated animals. in the "inducible" c57b/6j strain of mice, 3-methylcholanthrene and phenobarbital pretreatment cause an increase in cytochrome p-448 and p-450 levels, respect ... | 1978 | 96118 |
| partial purine nucleoside phosphorylase deficiency. studies of lymphocyte function. | immune function in two brothers with a deficiency of purine nucleoside phosphorylase was evaluated in vivo and in vitro. both patients had a history of recurrent infections and profound lymphopenia. studies of cell-mediated immunity revealed an absence of delayed cutaneous reactivity to a number of antigens, including dinitrochlorobenzene, and significantly reduced lymphocyte proliferative responses to nonspecific mitogens, specific antigen, and allogeneic cells. e-rosetting cells were present b ... | 1978 | 96131 |
| immunochemical studies of the inactivation of aspartate transcarbamylase by stationary phase bacillus subtilis cells. evidence for selective, energy-dependent degradation. | the aspartate transcarbamylase of bacillus subtilis is stable in exponentially growing cells, but undergoes rapid, energy-dependent inactivation when growth is inhibited by nutrient depletion or addition of antibiotics or other inhibitors of metabolism. this inactivation has been analyzed by a variety of immunochemical techniques, including direct and indirect immunoprecipitation of extracts of cells labeled with 3h-amino-acids, microcomplement fixation, and neutralization of enzymatic activity. ... | 1978 | 97299 |
| activity of azlocillin and mezlocillin against gram-negative organisms: comparison with other penicillins. | the activities of azlocillin and mezlocillin were compared with those of carbenicillin, ticarcillin, and pirbenicillin against a wide range of gram-negative organisms. the two new drugs were considerably more active than carbenicillin against klebsiella species and escherichia coli. carbenicillin was twice as active against proteus mirabilis as mezlocillin and four times as active as azlocillin. against pseudomonas aeruginosa, azlocillin was eight times as active as carbenicillin. azlocillin and ... | 1978 | 96726 |
| visual-field displacements in human beings evoked by accoustical transients. | sixty-two of 133 subjects reported visual-field displacements when they were exposed to intense (125 db spl) repetitive audiofrequency transients. this phenomenon was investigated in three experiments. frequency (100-5000 hz) was varied in experiment i; repetition rate (0.5/s--6.0/s) was varied in experiment ii; acoustical transient onset/offset time (0.2--25 ms) was examined in experiment iii. the results of these three experiments indicated that the largest proportion of displacement reports a ... | 1978 | 98550 |
| [utilization of the halothane test in the detection of the malignant hypertension syndrome [mhs] in pigs]. | by the halothane test we determined the development of the syndrome of malignant hyperthermia in pigs of the belgian landrace breed with body weight of 20 kg. we found that from 27 animals that were subjected to the test 12 positively reacted to narcotan - spofa anaesthesis. pigs with the syndrome of malignant hyperthermia had considerably higher rectal temperature after anaesthesis, lower ph of venose blood, higher concentration of lactic acid and glucosis in the blood plasma. halothane-negativ ... | 1978 | 97839 |
| jaundice and breast-feeding among alaskan eskimo newborns. | the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ... | 1978 | 99026 |
| transformation of marmoset lymphocytes in vitro with herpesvirus ateles. | circulating lymphocytes from three species of marmoset monkeys were transformed in vitro with herpesvirus ateles (hva) either by co-cultivation with lethally x-irradiated hva-producing lymphoblastoid cells or by infection with cell-free virus: 42 transformed lymphocyte cultures were obtained from 72 transformation attempts. attempts to transform squirrel monkey lymphocytes were unsuccessful in 29 attempts. association of hva with each transformed culture was demonstrated by staining of antigen-p ... | 1978 | 96033 |
| naturally occurring diatomaceous pneumoconiosis in sub-human primates. | 1978 | 96157 | |
| primary malignant teratoma of the thyroid: case report and literature review of cervical teratomas in adults. | a case of primary malignant teratoma of the thyroid in a gravid 37-year-old female is reported and the literature on cervical teratomas in adults reviewed. the patient was treated by total thyroidectomy and left radical neck dissection followed by cervical and mediastinal radiotherapy and chemotherapy. she fied of recurrent tumor and related complications 9 months after discovery of the lesion. this is the 6th case of primary teratoma of the thyroid and the 9th case of cervical teratoma reported ... | 1978 | 352506 |
| normal cardiac function with a hybrid heart. | a left ventricular bypass procedure using a cardiac allograft was performed in a patient with a long history of rheumatic heart disease and two aortic valve replacements. normal cardiac function was reestablished, and the only problem following transplantation was that of serious arrhythmias involving the recipient heart. eighteen months after left ventricular bypass bacterial endocarditis which was resistant to medical treatment developed on the aortic prosthesis. the patient underwent operatio ... | 1978 | 352288 |
| cytoplasmic streaming in amoeboid movement. | 1978 | 352246 | |
| a study of the social relationships in a free-ranging troop of stumptail macaques (macaca arctoides). | 1978 | 352367 | |
| [blood serum content of fucose and neutral hexoses in patients with acute viral hepatitis]. | 1978 | 1145296 | |
| penicillins. | 1978 | 352250 | |
| [nikolai grigor'evich kolosov (on his 80th birthday)]. | 1978 | 352306 |