Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| cultures of chlamydia trachomatis in mouse peritoneal macrophages: factors affecting organism growth. | growth of chlamydia trachomatis b/tw-5/ot and l(2)/434/bu strains in cultures of thioglycolate-activated mouse peritoneal macrophages was studied. both strains grew to a limited extent in the macrophages, but lymphogranuloma venereum (lgv) grew better than trachoma. growth was enhanced by centrifugation of the inoculum onto the macrophage cell layer and inhibited by pretreatment of macrophages for 2 h with 100 mug of concanavalin a per ml. no significant effect was observed by pretreatment of ma ... | 1978 | 566729 |
| comparison of synchronization of primate circadian rhythms by light and food. | several circadian rhythms in squirrel monkeys (saimiri sciureus) entrained by two different agents were studied to compare their mode of coupling with the environmental zeitgebers. synchronization was accomplished either by light-dark cycles consisting of 12 h of 600 lx followed by 12 h of less than 1 lx (ld 12:12), or by eat-fast cycles in which the animals could eat for 3 h and then had to fast for the remaining 21 h each day (ef 3:21). the rhythms of drinking, colonic temperature, and urinary ... | 1978 | 415621 |
| chlamydial infections (first of three parts). | 1978 | 340951 | |
| chlamydial infections (third of three parts). | 1978 | 342952 | |
| parasite-specified phagocytosis of chlamydia psittaci and chlamydia trachomatis by l and hela cells. | phagocytosis of the 6bc strain of chlamydia psittaci and the lymphogranuloma venereum 440l strain of chlamydia trachomatis by l cells and hela 229 cells occurred at rates and to extents that were 10 to 100 times greater than those observed for the phagocytosis of escherichia coli and polystyrene latex spheres. both species of chlamydia were efficiently taken up by host cells of a type they had not previously encountered. phagocytosis of chlamydiae was brought about by the interaction of parasite ... | 1978 | 344217 |
| gentamicin use and pseudomonas and serratia resistance: effect of a surgical prophylaxis regimen. | an outbreak of prosthetic valve endocarditis due to methicillin-resistant staphylococcus epidermidis prompted a change in antimicrobial prophylaxis for open heart surgery in a general hospital from a regimen of aqueous penicillin g, methicillin, and kanamycin to a 5-day regimen of cefazolin and gentamicin. as a result, total gentamicin use in the hospital more than doubled. increased resistance of pseudomonas and serratia isolates paralleled the increased total use of gentamicin. for pseudomonas ... | 1978 | 348094 |
| lack of correspondence between virus-induced human leukocyte interferon and concanavalin a-induced human migration inhibitory factor (mif). | 1978 | 348158 | |
| regulation and significance of amino acid metabolism in skeletal muscle. | 1978 | 350636 | |
| rapid detection of experimental e. coli endophthalmitis by the limulus lysate test. | experimental e. coli endophthalmitis was produced in rabbits. the limulus lysate test was applied to aqueous and vitreous samples at various intervals after the intravitreal injection of e. coli organisms. results indicated that this test is feasible using vitreous and aqueous samples. the limulus test was positive for e. coli endotoxin within hours after infection, requiring only 1 hr to determine the presence of endotoxin after sampling. this test may have some value in the rapid diagnosis of ... | 1978 | 350804 |
| temperature-dependent variation in the synthesis of streptococcal group-specific carbohydrate. ii. biosynthetic studies in group a and variant strains. | the biosynthesis of the cell wall polysaccharide and peptidoglycan of group a and a-486-var streptococci was studied with n-acetyl-[14c]glucosamine, udp-n-acetyl-[14c]glucosamine, and [14c]glucose. the incorporation of n-acetyl-[14c]-glucosamine into the cell wall four times greater in the a-486-var cells than in the group a cells. however, the percentage of the total label incorporated into the cell wall polysaccharide at 37 degrees c by the a-486-var strain was 12%, compared with 66% for the g ... | 1978 | 350826 |
| outer membrane-dependent transport systems in escherichia coli: turnover of tonb function. | recent reports demonstrated that the energy-dependent step of vitamin b12 uptake into cells of escherichia coli rapidly declines after cessation either of the expression of the tonb gene or of general protein synthesis. it is shown here that inhibition of protein synthesis results in the decline, with similar kinetics, of all tonb-dependent processes, including sensitivity to colicins b and ia, irreversible adsorption of phage phi80, and siderophore-mediated iron uptake. the role of ongoing tonb ... | 1978 | 350836 |
| intestinal apoproteins during fat absorption. | to compare the roles of apolipoprotein (apo) a-i, b, and e (or arginine-rich apoprotein, arp) in the intracellular production of intestinal chylomicrons (and/or vldl), these apoproteins were localized in rat intestinal mucosa by the light microscope method of indirect immunofluorescence. in addition, tissue levels of apoa-i and apob were measured during fat absorption by radioimmunoassay. antisera were produced using apoa-i isolated from rat plasma high density lipoprotein, and apob and arp from ... | 1978 | 350901 |
| [physicochemical properties of l-asparaginase with antitumor activity (author's transl)]. | 1978 | 351095 | |
| immune surveillance and tumors of the nervous system. | the theory of immune surveillance postulates that one function of the immune system is to eliminate small numbers of malignant cells that arise spontaneously within the organism. although there has been a great deal of both clinical and experimental evidence in favor of thistheory as it applies to general oncology, the question of whether or not such a surveillance system would be effective for tumors arising within the nervous system has never been studied. the young of pregnant rats which had ... | 1978 | 351150 |
| use of a heavy inoculum in the in vitro evaluation of the anti-staphylococcal activity of 19 cephalosporins. | the in vitro activity of 19 cephalosporins against 105 clinical isolates of staphylococcus aureus and s. epidermidis was determined by using a heavy inoculum, i.e., 10(8) to 10(9) organisms per ml, to maximally challenge the antibiotics. the anti-staphylococcal activities of cephaloridine and 87/312 were consistently decreased by the use of a heavy inoculum when compared with the activity obtained with two less-concentrated inocula. the activity of most of the other compounds was also decreased ... | 1978 | 352261 |
| the relationship between the spot gene, the synthesis of stable rna, ribosomal proteins, and the beta beta' subunits of rna polymerase following a nutritional shiftup of escherichia coli. | the level of ppgpp and rates of synthesis of stable rna, ribosomal protein, and the beta and beta' subunits of rna polymerase were measured following a nutritional shiftup in escherichia coli strains, nf 929 (spot+) and nf 930 (spot-). in the spot+ strain, ppgpp levels decreased 50% within 2 min following shiftup, and the rates of synthesis of stable rna, ribosomal proteins, and the beta and beta' subunits of rna polymerase increased with little or no lag. in contrast, in the spot- strain, ppgpp ... | 1978 | 352488 |
| immediate cytotoxicity of chlamydia trachomatis for mouse peritoneal macrophages. | the toxicity of chlamydia trachomatis was studied with mouse peritoneal macrophage culture. inoculation of 30 inclusion-forming units of trachoma b/tw-5/ot organisms and 250 inclusion-forming units of lymphogranuloma venereum l2/434/bu organisms per cell caused immediated toxicity, with the killing of 40 to 90% of the macrophages within 6 h after inoculation. inhibition of phagocytosis by adsorption at 0 degrees c or by naf pretreatment of macrophages prevented the toxicity, indicating that chla ... | 1978 | 352950 |
| serotyping of chlamydia: antibodies to lymphogranuloma venereum strains compared by microimmunofluorescence and neutralization tests. | the microimmunofluorescence test with hyperimmune rooster sera against lymphogranuloma venereum strains gave the same serotype patterns obtained in the standard mouse serum system. results in a plaque reduction test appeared similar when only 3 prototype strains were tested, but differed when a battery of 11 strains were tested. | 1978 | 352964 |
| coupling of escherichia coli lipopolysaccharide to epoxy-activated sepharose 6b. | escherichia coli o111:b4 lipopolysaccharide was coupled to epoxy-activated sepharose 6b. the bound lipopolysaccharide was immunogenic and immunoadsorptive although at less efficiency than free lipopolysaccharide. | 1978 | 352965 |
| the time factor in carcinogenesis. the 1977 sievert lecture. | 1978 | 353001 | |
| chlamydial infections in paediatrics. | 1978 | 356747 | |
| rapid serological test for diagnosis of chlamydial ocular infections. | a rapid serodiagnostic test for the diagnosis of paratrachoma (tric ophthalmia neonatorum, inclusion conjunctivitis, tric punctate keratoconjunctivitis, and trachoma of sexually transmitted origin) has been developed. the technique is based on using a modified micro-immunofluorescence test for detecting antichlamydial igg and igm in the blood and igg and iga in tears. the blood samples are collected on cellulose sponges after a finger prick, and tears are collected by introducing small sponges i ... | 1978 | 356871 |
| chlamydia trachomatis from men with non-gonococcal urethritis. simplified procedure for cultivation and isolation in replicating mccoy cell culture. | chlamydia trachromatis was cultivated on replicating mccoy cells without the addition of antimetabolites. a further technical modification was centrifugation of the specimens at room temperature at 4000 g, thus making it possible to use the method in any microbiological laboratory. c. trachomatis was isolated from 36 of 81 patients (44.4%) with non-gonococcal urethritis. this rate compares well with reported isolation rates using antireplicative agents and higher centrifugation temperatures. | 1978 | 358749 |
| single-antigen immunofluorescence test for chlamydial antibodies. | a simple method is presented for producing large numbers of inclusions of chlamydia trachomatis serotype l2 in cell cultures on slides for immunofluorescence antibody staining. preliminary results with a total of 1,241 human sera from different groups were consistent with findings by earlier methods: 82% of chlamydia-positive men with nongonococcal urethritis had antibodies at titers of greater than or equal to 8, with a geometric mean titer (gmt) of 44.9; 68.5% of chlamydia-negative men with no ... | 1978 | 359585 |
| rapid diagnosis of chlamydial infection of the cervix. | a rapid serodiagnostic test for the presumptive diagnosis of chlamydial infection of the cervix has been developed. the method used in based on the modified micro-immunofluorescence test using pooled chlamydial antigens and the detection of different immunoglobulin classes of chlamydial antibody in sera and cervical secretions. the presence of igg chlamydial antibody at a level of 1/64, or igm antibody at a level of 1/8 or greater, or both in sera and igg or iga antibody at a level of 1/8 or mor ... | 1978 | 367526 |
| a simple method for the multiple tissue culture assay of chlamydia trachomatis. | 1978 | 368489 | |
| identification of tubulin from the yeast saccharomyces cerevisiae. | a tubulin-like protein was identified in the lower eukaryote saccharomyces cerevisiae. the following criteria were used: (i) copolymerization of the 35s-labeled yeast protein with porcine brain tubulin; (ii) immunoprecipitation of the 35s-labeled yeast protein with antiflagellar tubulin antibody; (iii) the presence of the yeast protein as a constituent of isolated yeast nuclei; and (iv) splitting of the yeast protein in a gel electrophoretic system containing sodium dodecyl sulfate that resolved ... | 1978 | 368805 |
| influence of specificity of reagents and of behaviour of cell surface ig on the detection and enumeration of immunoglobulin-bearing lymphocytes in humans. | some parameters likely to influence detection and classification of human b-lymphocytes using anti-immunoglobulin (ig) sera have been investigated. of 20 separate mono- and polyspecific native or conjugated anti-ig sera analysed by a passive haemagglutination technique, 13 exhibited non-specific reactivity. this technique showed no consistent correlation between the titre of individual sera against fab2 and whole igg respectively. the indirect immunofluorescence (if) method applied to detect sur ... | 1978 | 307583 |
| variation in shape of the human kidney in ontogenetic development. | 1978 | 308913 | |
| apparatus for uniaxial testing of soft human tissues in vitro. | 1978 | 309051 | |
| the use of cycloheximide-treated cells for isolating trachoma agents under field conditions. | standard procedures for the isolation of chlamydia trachomatis require pretreatment of the tissue culture cells. we evaluated the use of cycloheximide, an antimetabolite that can be added to the cells with the inoculum. cycloheximide-treated cells provided a sensitive system for isolating trachoma agents. this system was applicable to field studies as requirements for equipment were minimal and the cells were 2 weeks old when inoculated. | 1978 | 310363 |
| [the influence of cryoprotective solutions on the ultrastructure of rabbit corneal endothelium (author's transl)]. | a series of rabbit corneae was preserved at -196 degrees c in liquid nitrogen using five different cryoprotective solutions: (1) 5% dextran t 40, (2) 10% polyvinylpyrrolidone, (3) 5% dextran t 40 + 10% polyvinylpyrrolidone + dimethyl sulfoxide, (4) 25% rabbit albumin + 10% polyvinylpyrrolidone, (5) 25% rabbit albumin + dimethyl sulfoxide. after thawing the corneae, the influence of the different cryoprotective solutions on the ultrastructure of corneal endothelium was evaluated and compared with ... | 1978 | 311165 |
| dupuytren's disease presenting as palmar pits. | a 37 year old man with a non-hodgkin's lymphoma and a history of heavy alcohol use presented with bilateral palmar pits. similar lesions were noted in several family members, some of whom had limited use of the hands. although the patient was referred for evaluation of the palmar pits of the basal cell nevus syndrome, close evaluation revealed the diagnosis of dupuytren's disease. | 1978 | 284078 |
| [human need for basic exercise - the bedridden patient]. | 1978 | 261380 | |
| musculoskeletal tumors in dogs. | 1978 | 272367 | |
| [effect of propyl-2-pentene-2-oic acid on gaba levels in different regions of mouse brain]. | an elevation in cerebral gaba level (65%) is observed after administration of an anticonvulsant, sodium propyl 2-pentene-2 oate, a branched chain fatty acid, comformationally restricted gaba analogue, competitive inhibitor of gaba-t in regard to gaba. the concentration of gaba increases in some regions i.e. substantia nigra, frontal and temporal cortex, cerebellum and olfactory bulbs. the gaba level remains unchanged in caudate nucleus, hippocampus and occipital cortex. results are discussed com ... | 1978 | 154951 |
| [dwarf colony mutants of escherichia coli: plasmids resistant to antibiotics]. | deficient dwarf colony (ddc) mutants of e. coli k 12, harboring or no resistance plasmids, were obtained in vitro. the r plasmids of parental strains and to ddc mutants were transfered by conjugation to normal colony, and to ddc mutants of e. coli k 12; the frequencies of transfer were similar for all strains studied. | 1978 | 154954 |
| biochemical and clinical effects of ethane-1-hydroxy-1,1-diphosphonate in calcium nephrolithiasis. | 1. the short- and longer-term effects of ethane-1-hydroxy-1,1-diphosphonate (ehdp), an inhibitor of crystal growth and potential preventive agent against urinary tract stones in man, have been studied. 2. measurement of urinary excretion of ehdp was used to define the best dosage regimen. when 4.4 mmol of ehdp mmol of ehdp was given in four divided doses the murinary concentration of ehdp achieved was high enough (10-5 mol/1) to inhibit the crystallization of calcium crystals throughout the day. ... | 1978 | 108043 |
| doubled fourth-day colorectal anastomotic strength with complete retention of intestinal mature wound collagen and accelerated deposition following immediate full enteral nutrition. | 1978 | 122623 | |
| in vitro assays of the efficacy of antimicrobial agents in controlling chlamydia trachomatis propagation. | the antimicrobial susceptibility of a low-laboratory-passage, slow-growing, genital chlamydia trachomatis strain was studied by five different procedures with the use of mccoy cells pretreated with 5-iodo-2-deoxyuridine. the effects of antimicrobial agents when added to cultures on day 0 or day 2 after inoculation with c. trachomatis and the effects of washing and reincubating treated cultures in antimicrobial-free media were investigated. tetracycline and erythromycin inhibited c. trachomatis g ... | 1978 | 162541 |
| changes in the immunoglobulin levels of the mouse gut and serum during conventionalisation and following administration of salmonella typhimurium. | increasess in all immunoglobulin classes, except igm, were observed in the sera of specific pathogen-free (spf) mice beginning 10 days after their removal from barrier conditions. concentrations of serum immunoglobulins, comparable with those of conventional mice, were obtained in these animals between 21 and 35 days. following the removal of germ-free mice from their sterile isolaters, their intestinal iga levels increased over 35 days to attain levels found in conventional animals. a marked in ... | 1978 | 156538 |
| electromyographic study on experimental hyperkalaemia. ii. effects on neuromuscular transmission. | 1978 | 228534 | |
| [a serological study of respiratory infections in pilgrims to mecca]. | 1978 | 229604 | |
| [substrate specificity and kinetic properties of phosphoprotein phosphatase from mesenterial lymph nodes of rats]. | 1978 | 230125 | |
| a recently recognized infectious disease. | 1978 | 249422 | |
| effects of theophylline and n6,o2-dibutyryl adenosine 3':5'-monophosphate on sympathetic ganglionic transmission in rats. | the effects of theophylline and n6,o2-dibutyryl adenosine 3':5'-monophosphate (dbcamp) on the amplitude of the postganglionic action potential during and after a 10 hz repetitive volley, and 50 to 1000 msec after a conditioning stimulus were investigated. the effects of both drugs on some electrophysiological properties of single cells of the isolated superior cervical ganglia of rats were also studied. at low concentrations of theophylline a reversible potentiation of the compound action potent ... | 1978 | 204771 |
| enhanced virus replication in mammalian cells exposed to commercial emulsifiers. | mammalian cell cultures were used to show that a variety of commercial emulsifiers are capable of enhancing the sensitivity of these cells to infection with several viruses. some emulsifiers were not active as enhancers, and those viruses that responded to the enhancing emulsifiers were single-stranded ribonucldic acid viruses. the double-stranded viruses that were tested were nonresponders. | 1978 | 205172 |
| the effect of birth and related hormonal events on the neonatal development of uridine diphosphate glucuronosyltransferase activity towards bilirubin and other substrates in rat liver [proceedings]. | 1978 | 205461 | |
| isotope-tapping experiments with rabbit liver fructose bisphosphatase. | isotope-trapping experiments with mental-free rabbit liver fructose 1,6-bisphosphatase have shown that enzyme-bound d-fructose 1,6-bisphosphate completely dissociates prior to enzyme turnover initiated by mn2+ as the catalytic metal. the exchange rate of the binary enzyme-d-fructose 1,6-bisphosphate complex with the substrate pool is, therefore, more rapid than its conversion to products, suggesting that structural mn2+ is necessary for productive substarate binding. rapid-quench isotope-trappin ... | 1978 | 207315 |
| possible role of the proximal convoluted tubules of human kidney in chronic glomerulonephritis. a quantitative electron-microscopic study. | the amount of forming pinocytic (coated) microvesicles on the apical plasma membrane of kidney proximal tubule cells was assessed in kidney biopsies of 10 patients suffering from chronic glomerulonephritis. a significant correlation was found between the amount of these vesicles and diurnal proteinuria levels (r = 0.889; p less than 0.01). the possible mechanisms of protein reabsorption via pinocytosis in both normal and pathological conditions are considered. | 1978 | 208014 |
| the serine protease from rat liver and hepatoma 8999. location and role in mitochondrial protein degradation. | 1. hepatoma 8999 showed extremely high activity of serine protease, but similar activities of other lysosomal proteases to those of normal rat liver. 2. serine protease from rat liver formed a single immunoprecipitation band against antiserum to purified protease from hepatoma 8999. 3. the serine proteases in rat liver and hepatoma 8999 were restricted to the inner membranes of the mitochondrial fraction. 4. polyacrylamide gel electrophoresis with sodium dodecylsulfate showed that hepatoma 8999 ... | 1978 | 209014 |
| demonstration of saturation kinetics in the intestinal absorption of vitamin c in man and the guinea pig. | intestinal absorption of ascorbic acid is believed to be mediated through a sodium-dependent active transport process in man and in the guinea pig, both species having a nutritional requirement for the vitamin. vitamin c transport was studied in man and in the guinea pig by in vivo intestinal perfusion of concentrations of vitamin c ranging from physiologic to clearly pharmacologic levels. triple lumen intestinal perfusion of seven human volunteers with vitamin c concentrations ranging from 0.85 ... | 1978 | 209065 |
| oxytocin release following osmotic activation of oxytocin neurones in the paraventricular and supraoptic nuclei. | 1. recordings were made from a total of 35 antidromically identified neurones in the paraventricular (pv) and supraoptic (so) nuclei of urethane-anaesthetized lactating rats. during recording plasma osmotic pressure was raised by 12 m-osmole/kg by injection of hypertonic solutions of nacl, licl, or mannitol.2. nine pv neurones (mean firing rate 4.2 +/- 1.0 (s.e.) spikes/sec) were classified as oxytocin cells because they gave a burst of activity before reflex milk-ejections. none of these showed ... | 1978 | 209173 |
| the h1 class of histone and diversity in chromosomal structure. | 1978 | 209584 | |
| inhibition of t4 polynucleotide kinase by the atp analog, beta, gamma-imidoadenylyl 5'-triphosphate. | the inhibition of t4 polynucleotide kinase by beta,gamma-imidoadenylyl 5'-triphosphate has been investigated. it was found that the atp analog was a competitive inhibitor with regard to atp and a noncompetitive inhibitor with regard to dna possessing a 5'-hydroxyl group. at ph 8.0, the ki values were 3 and 11 mm, respectively. beta,gamma-imidoadenylyl 5'-triphosphate was not a substrate in the forward reaction, but would replace adp and atp in the reverse reaction. the reverse reaction was also ... | 1978 | 210816 |
| broiler-breeder vaccination against infectious bursal disease and persistence of maternal antibody in progeny. | 1978 | 210922 | |
| diagnosis and etiology of nongonococcal urethritis. | the observation of more than four polymorphonuclear cells (pmn) per high-power field (hpf) in gram-stained smears of urethral secretions was found to differentiate patients with urethritis from patients without urethritis. a urethral discharge was present in 78% of patients with nongonococcal urethritis (ngu). dysuria without demonstrable urethral discharge and with fewer than four pmn/hpf did not appear to fit into the ngu spectrum. ngu is now defined to include men who have negative urethral c ... | 1978 | 213495 |
| sendai virus infection in a small mouse breeding colony. | 1978 | 213634 | |
| purification of bacterial cytochrome c by isoelectric focusing. | 1978 | 213681 | |
| absence of cytotoxic effect of selected pathogens on hla b27 positive fibroblasts. | 1978 | 213785 | |
| calcium-dependent 3':5'-cyclic nucleotide phosphodiesterase. inhibition of basal activity at physiological levels of potassium ions. | a calcium-dependent cyclic nucleotide phosphodiesterase from rat cerebrum was, in the absence of activator protein, inhibited by various monovalent cations. the inhibition was rapid, readily reversible, and concentration-dependent, with 100 mm cesium, rubidium, or potassium ion inhibiting essentially all basal enzyme activity, while 100 mm sodium or lithium ions produced only moderate inhibition. the potency of the cations in inhibiting the enzyme was cs greater than or equal to rb greater than ... | 1978 | 214428 |
| s49 lymphoma wild type and variant clones contain normal calcium dependent regulator. | calcium dependent regulator is present in wild-type s49 lymphoma cells, in the variant that is deficient in adenylate cyclase activity (ac-), and in the uncoupled variant (unc). the electrophoretic mobility and the ability to stimulate cyclic nucleotide phosphodiesterase of the calcium dependent regulator from each of these three clones are indistinguishable from those of the modulator protein isolated from bovine brain. calcium dependent regulator does not appear to be involved in the defect re ... | 1978 | 214461 |
| the interaction between mitochondrial nadh-ubiquinone oxidoreductase and ubiquinol-cytochrome c oxidoreductase. evidence for stoicheiometric association. | 1. the nadh-ubiquinone oxidoreductase complex (complex i) and the ubiquinol-cytochrome c oxidoreductase complex (complex iii) combine in a 1:1 molar ratio to give nadh-cytochrome c oxidoreductase (complex i-complex iii). 2. experiments on the inhibition of the nadh-cytochrome c oxidoreductase activity of mixtures of complexes i and iii by rotenone and antimycin indicate that electron transfer between a unit of complex i-complex iii and extra molecules of complexes i or iii does not contribute to ... | 1978 | 215122 |
| the relative significance of spinal cord norepinephrine and 5-hydroxytryptamine in electrically-induced seizure in the rat. | 1978 | 148011 | |
| hormonal regulation of ovarian folliculogenesis in rhesus monkeys: i. concentrations of serum luteinizing hormone and progesterone during laparoscopy and patterns of follicular development during successive menstrual cycles. | 1978 | 149571 | |
| [n[2-hydroxyethyl] palmitamide repeated administration effect on interferon production in mouse organism after phage double-stranded ribonucleic acid [ds-rna] application (author's transl)]. | 1978 | 149599 | |
| [new data on serotonin control of sexual receptivity in the rat]. | serotonin was shown to be involved in the mechanisms whereby olfactory bulbs controlled sexual receptivity between 18 and 19 hrs. on prooestrus in 4-day cyclic female rats. | 1978 | 149613 |
| polyamine-induced actin polymerization. | muscle actin has been found to polymerize reversibly upon addition of low concentrations of polyamines. this polymerization, studied by centrifugation, has shown a linear relationship between the actin polymerization yield and the chain length of the polyamine. among the biological polyamines tested, spermidine and spermine are the most efficient. the polymerization of actin can also be induced by the corresponding mono or diguanidine derivatives of these polyamines but monoamines or amino acids ... | 1978 | 149658 |
| [the effect of concomitant administration of dehydroepiandrosterone with progesterone on decidual growth in the rat (author's transl)]. | studies were made on the effect of concomitant administration of dehydroepiandrosterone acetate (dha-ac) with progesterone on decidual growth in the rat. virgin female rats of wistar strain weighing about 250 g were used. daily vaginal smears were recorded and, during the time of vaginal cornification, the animals were made pseudopregnant by tapping the uterine cervix. day 1 of the pseudopregnancy was designated as the day that the vaginal smears contained primarily leucocytes. on day 4 of the p ... | 1978 | 149679 |
| effect of human immunoglobulin preparations on fc rosette formation between anti-d-coated erythrocytes and lymphocytes. | human immunoglobulin (ig) preparations were tested for their inhibitory effect on fc rosette formation between anti-d-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. both of the two biological activities ascribed to the sites in the fc portion of the igg molecules were found to be reduced in the pepsin-treated, as well as in the s-sulfonated ig preparations, as compared to the activities of the normal human ig preparation. in the plasmin-treated ig ... | 1978 | 150144 |
| structure of alpha-polymer from in vitro and in vivo highly cross-linked human fibrin. | peptides derived from plasmic and cyanogen bromide (cnbr) cleavage of highly cross-linked fibrin were isolated and characterized by sodium dodecyl sulfate-gel electrophoresis, amino acid analyses, cyanoethylation, and nh2-terminal analyses. extended plasmic digestions of human fibrin containing four epsilon-(gamma-glutamyl)lysine cross-links per molecule produced a peptide of alpha-chain origin (mr congruent to 21,000) which was comprised of a small donor peptide cross-linked to the acceptor sit ... | 1978 | 150419 |
| [raised prostaglandin e-2 level in focal inflammatory lesions of the human skin with particular reference to rosacea]. | 1978 | 151301 | |
| [morphological changes in the digestive organs during prolonged space flight on the kosmos-782 biosatellite]. | a reduction in the content of neutral mucopolysaccharides in mucous cells of the neck, a slight decrease in the activity of succinate dehydrogenase and nad-diaphorase in parietal cells, a decrease in the dna synthesis rate, and an increase in the area of mitochondria and cristae were detected in the gastric mucosa of rats which were in a long-term space flight. in the small intestine, an increase in the activity of glucose-6-phosphate dehydrogenase and leucine aminopeptidase were found. morpholo ... | 1978 | 152100 |
| chlamydia trachomatis in gonococcal and postgonococcal urethritis. | chlamydia trachomatis was isolated from the urethra of 38 (28.6%) out of 133 men with gonococcal urethritis (gu). during the follow up of 72 men postgonococcal urethritis (pgu) was diagnosed in 50 (69.5%) patients. more than half (30 out of 50) of these patients with pgu were chlamydia-positive. out of 31 patients with chlamydia 30 developed pgu whether or not procaine penicillin, spectinomycin, or gentamicin were used. these findings are discussed in relation to present recommendations for the ... | 1978 | 152142 |
| guinea-worm infection in banaskantha district of gujarat--some important epidemiological aspects. | 1978 | 153328 | |
| comparison of thymidine, fluorodeoxyuridine, hydroxyurea, and methotrexate blocking at the g1/s phase transition of the cell cycle, studied by replication patterns. | cultures of human amniotic fluid cells and fibroblasts were temporarily blocked by the replication inhibitors thymidine (dt) surplus, fluorodeoxyuridine (fdu), hydroxyurea (hu), or methotrexate uridine (mu). the respective arresting point at g1-s transition and the homogeneity of the blocked cell population were determined by means of brdu replication patterns. most variation of patterns were found after hu. after mu, cells were arrested before the onset of replication, while with dt surplus of ... | 1978 | 153886 |
| isolation of neurospora crassa-bovine l-glutamate dehydrogenase hybrids [proceedings]. | 1978 | 154423 | |
| isolation of neurospora crassa-bovine l-glutamate dehydrogenase hybrids [proceedings]. | 1978 | 154423 | |
| [induction of estrus and ovulation in prepuberal young pigs by treatment with gonadotropin]. | 1978 | 98941 | |
| the roles of endothelium, platelets, and smooth muscle cells in intimal healing. | the continual remodeling of the artery wall significantly narrows the lumen. it contributes to the development of atherosclerotic plaque through the incorporation of lipid into the arterial intima. the steps in the repair of arterial intima include platelet accumulation followed by leukocyte attachment to denuded areas, smooth muscle migration from the media, deposition of extracellular connective tissue components, and endothelial progression seem related to re-endothelialization, platelets, th ... | 1978 | 98967 |
| microradiographic demonstration of pyelolymphatic backflow in the porcine kidney. | pyelolymphatic backflow occurs when intrapelvic pressure rises acutely. although peripelvic and hilar lymphatics have occasionally been demonstrated during intravenous urography and retrograde pyelography, the patterns of intrarenal microlymphatic filling have not previously been studied radiographically in multipapillary kidneys. microradiography was performed after retrograde ureteral injections of barium sulfate suspension in recently excised pig kidneys. contrast filled the ducts of bellini ... | 1978 | 98998 |
| jaundice and breast-feeding among alaskan eskimo newborns. | the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ... | 1978 | 99026 |
| oligosaccharides and polysaccharides specifically utilizable by bifidobacteria. | 1978 | 103638 | |
| effects of increased left ventricular work, hypoxia, or coronary ligation on hearts from rats at high altitude. | isolated perfused hearts from rats acclimatized to jungfraujoch (altitude 3454 m) were less resistant to the effects of high levels of heart work or mild hypoxia than hearts from litter mates reared at geneva (340 m). however, in response to coronary artery ligation hearts from acclimatized rats were better able to maintain tissue contents of adenosine triphosphate, phosphocreatine and glycogen. a projected explanation for the increased biochemical resistance to ischaemia was a relative increase ... | 1978 | 103723 |
| chlamydia trachomatis cervicitis in gynecologic outpatients. | symptoms suggestive of a lower genital tract infection (lgti) are common complaints in women who consult gynecologists. sexually transmitted microorganisms, such as chlamydia trachomatis. neisseria gonorrhoeae, and trichomonas vaginalis, are responsible for a substantial proportion of lgti. this study was performed to establish the frequency of lgti caused by c trachomatis in women attending a gynecologic outpatient clinic. of 170 women with lgti, 32.9% harbored one or more of these organisms: c ... | 1978 | 104212 |
| studies on acute and late stages of experimental central retinal artery occlusion in the cynomolgus monkey. i. intensity-amplitude relations of the d.c. recorded erg with special reference to the c-wave. | the main positive component of the c-wave of the erg is generated by the pigment epithelium-receptor complex, which is supplied from the choroidal circulation. occlusion of the central retinal artery (ocra) causes serious morphological damage only to the inner retina. an effect on the c-wave is therefore not primarily to be expected. in this study on five cynomolgus monkeys with unilateral, laser-induced ocra the c-wave was decreased, slightly in the early stage and markedly in the late stage. a ... | 1978 | 104542 |
| on the appearance of bacillus subtilis intracellular serine protease in the cell membrane and culture medium. comparison of the enzyme and other bacillus subtilis serine proteases. | while about 80% of the cell-bound intracellular serine protease of bacillus subtilis a-50 have been recovered in the soluble fraction upon disruption of cells, the rest of the enzyme was found to be associated with the membrane fraction. soluble cytoplasmic intracellular serine protease, as well as membrane-bound serine protease liberated by non-ionic detergent treatment, have been isolated in a pure state and shown to be identical. the same protease might also be found extracellularly, due pres ... | 1978 | 104693 |
| isolation of chlamydia trachomatis from bartholin's ducts. | exudate from bartholin's ducts from 30 selected patients was investigated for chlamydia trachomatis and neisseria gonorrhoeae. n. gonorrhoeae was isolated from the duct exudate in 24 patients and c. trachomatis in nine. concurrent infection of the ducts was present in seven (29.2%); the remaining two patients were sexual contacts of men with non-specific urethritis. the duct exudate was mucopus in seven patients, cloudy mucus in one, and clear mucus in the other. although contamination of the vu ... | 1978 | 104771 |
| is bacillus subtilis atcc 6633 a beta-lactamase producer? | 1978 | 104947 | |
| [leg ulcer caused by a monkey's bite]. | 35 days following a monkey's bite, the ulcer observed showed total necrosis associated with spotted zones of necrosis due to the deep penetration of the animal's teeth. it was treated like a regular ulcer and healed within seven weeks without complications. one should keep in mind that such ulcers involve infectious episodes due to the transmission of a pathogenic human-type flora through a septic orodental milieu: pathogenic cocci; pasteurella, shigella, salmonella; polio viruses or microbial a ... | 1978 | 99755 |
| controlled trial of 6-month and 8-month regimens in the treatment of pulmonary tuberculosis. first report. | four short-course antituberculosis regimens allocated at random were studied; (1) streptomycin, isoniazid, and rifampin given daily for 6 months; (2) these 3 drugs plus pyrazinamide given daily for 2 months, followed by twice-weekly administration of streptomycin, isoniazid, and pyrazinamide; (3) a regimen that differed from regimen 2 only in that ethambutol replaced pyrazinamide, and (4) streptomycin plus isoniazid plus rifampin plus pyrazinamide given 3 times per week for 4 months, followed by ... | 1978 | 100029 |
| effects of entrapment in liposomes on the distribution, degradation and effectiveness of methotrexate in vivo. | 1978 | 100041 | |
| [clebopride, a new orthopramide with potent and selective central antidopaminergic properties]. | 1978 | 100059 | |
| trifluridine in resistant human herpetic keratitis. | patients with active dendritic herpetic keratitis that was unresponsive to topical idoxuridine or vidarabine therapy were treated topically with a 1% solution of trifluridine. the dendritic ulcers healed in an average time of 6.1 days. all patients tolerated the drug well except for one patient in whom a reversible crystalline epithelial keratitis developed. | 1978 | 100084 |
| a kinetic study of ribulose bisphosphate carboxylase from the photosynthetic bacterium rhodospirillum rubrum. | the activation kinetics of purified rhodospirillum rubrum ribulose bisphosphate carboxylase were analysed. the equilibrium constant for activation by co(2) was 600 micron and that for activation by mg2+ was 90 micron, and the second-order activation constant for the reaction of co(2) with inactive enzyme (k+1) was 0.25 x 10(-3)min-1 . micron-1. the latter value was considerably lower than the k+1 for higher-plant enzyme (7 x 10(-3)-10 x 10(-3)min-1 . micron-1). 6-phosphogluconate had little effe ... | 1978 | 100101 |
| the distribution of hydrolytic enzyme activities in human fibroblast cultures and their intercellular transfer. | 1978 | 100108 | |
| control of cell multiplication: preparation and immunological comparison of inhibitory factors in the homogenate and perfusate of the adult rat liver. | the control of organ cell multiplication by a negative feed-back mechanism implies that factors of the inhibitory mechanism are present in the blood and are produced by the target organ itself. we have examined the inhibitors which are present in the cytosol of adult rat liver as well as in efferent fluid from an isolated perfused organ. these two materials yielded predominantly protein molecules having in common a molecular weight of approximately 80 000 daltons and an isoelectric point between ... | 1978 | 100149 |
| chlamydia trachomatis: a cause of an infantile pneumonia syndrome. | 1978 | 101061 | |
| a comparison of genital infections caused by chlamydia trachomatis and by neisseria gonorrhoeae. | patients with culture-proven infections with neisseria gonorrhoeae or chlamydia trachomatis, or both, seen at the olmsted county health department sexually transmitted disease clinic were evaluated for the presence of dysuria and exudate. eighty-four patients (21%) had neither symptom. n. gonorrhoeae infection alone was most frequent (47%), but c. trachomatis predominated in men. dysuria was most often detected in men infected with c. trachomatis, but exudate was most frequently found in men inf ... | 1978 | 101076 |
| cell-mediated immune responses in owl monkeys (aotus trivirgatus) with trachoma to soluble antigens of chlamydia trachomatis. | the first temporal study of the cell-mediated immune responses (cmi) following ocular infections with chlamydia trachomatis is presented. we examined the cmi of owl monkeys infected with trachoma to soluble antigens of c. trachomatis by leucocyte migration inhibition (lif) and delayed hypersensitivity skin testing. delayed hypersensitivity of a systemic nature developed after a local eye infection in owl monkeys; clearance of inclusions from conjunctival cells coincided with the onset of this re ... | 1978 | 101327 |