Publications

[classical and current aspects of the formation of motor dominance in man].	in the paper, significance of driving phenomenon for formation of motor dominant is considered and experimentally corroborated with the aid of autocorrelation and spectral analysis of the working man's eeg. the a.a. ukhtomsky classical postulate has been complemented by contemporary ideas of the role of phasic relationships between the cortical activity for extablishing intercentral interconnections and the functional differentiation of working and irrelevant cortical structures. data of corre ...	1975	165986
glomerular deposition of immune complexes in dogs following natural infection with canine adenovirus.	the renal lesions were studied in eight dogs which had either died as a result of acute canine adenovirus infection (rubarth's disease) or were in various stages of recovery from the clinical disease. using immunofluorescence techniques granular deposits of igg were detected in the glomeruli of six dogs; four of these animals had similar glomerular deposits of canine adenovirus antigen. eluates obtained from kidney tissue of four dogs were found to contain antiviral antibody. histologically thos ...	1975	166480
turnover of plasma total and very low density lipoprotein triglyceride in man.	basal plasma total triglyceride and very low density lipoprotein (vldl) triglyceride turnover rates were determined in 110 subjects whose triglyceride concentrations ranged from low normal to markedly elevated values. the mean total triglyceride turnover rate was 13.7 mg - kg-1- hr-1, whereas the mean vldl triglyceride turnover rate was 13.2 mg - kg-1 - hr-1. a highly significant correlation was present between the two turnover rates (r equal + 0.75). the endogenous serum triglyceride transporte ...	1975	167428
regulation of sensitivity to beta-adrenergic stimulation in induction of pineal n-acetyltransferase.	stimulation by isoproterenol causes large increases in the activity of rat pineal n-acetyltransferase (arylamine acetyltransferase or acetyl-coa:arylamine n-acetyltransferase, ec 2.3.1.5) after a variable lag period. lengthening periods of exposure to light cause rapid increases in the sensitivity of pineal n-acetyltransferase to induction by isoproterenol. this supersensitivity, which develops gradually over a 12 hr period, is correlated with increasingly longer lag periods in the induction of ...	1975	168570
a method fof production or antisera to hepatitis b antigen subtypes, and the distribution of subtypes d and y among norwegian hepatitis b patients.	a method for production of antisera to hepatitis b antigen (hbsag) subtypes d and y is described. the method is based on the coupling of hbsag to a colloidal silica gel (aerosil), and the selective adsorption of unwanted antibodies from antisera with this preparation. some results obtained with norwegian hepatitis patient sera are included.	1975	168728
antibody levels to parainfluenza, rubella, measles, and influenza a virus in children with polymyositis.	the cf and hi antibody titers to rubella and measles viruses, the cf titers to influenxa a, and the hi titers to parainfluenza 1, 2, and 3 were carried out on the sera of 20 patients with childhood polymyositis and their matched controls. the titers for measles, parainfluenxa 1, and influenza a were slightly higher for patients than for controls. the control group had antibody titers to rubella and parainfluenza 2 and 3 higher than or similar to those of patients. strong patterns or significant ...	1975	168906
functional consequences of modifying highly reactive arginyl residues of fructose 1,6-bisphosphatase. loss of monovalent cation activation.	modification of pig kidney fructose 1,6-bisphosphatase with 2,3-butanedione (in the presence of amp) results in the loss of activation of the enzyme by monovalent cations. under these conditions about 8 arginyl residues per mole of enzyme were modified. no other residues were modified. no loss of monovalent cation activation occurs when modification with 2,3-butanedione is carried out in the presence of amp plus the substrate fructose 1,6-bisphosphate and 3.2 less arginyl residues were modified. ...	1975	169892
cell-mediated cytotoxicity to chemically-induced rat tumours.	cell-mediated immune reactions against carcinogen-induced rat tumours were demonstrated by the in vitro microcytotoxicity test. lymph-node cells from syngeneic rats immunized against individual aminoazo-dye-induced hepatomas or 3-methylcholanthrene-induced sarcomas were cytotoxic for cells of the immunizing tumour compared with the effects of normal lymph-node cells. only a low level of cross-reactivity was detectable against target cells derived from otherr tumours. conversely, lymph-node cells ...	1975	170224
catabolite repression of pseudomonas aeruginosa amidase: isolation of promotor mutants.	among mutants of pseudomonas aeruginosa isolated from fluoroacetamide medium were some which synthesized amidase at about 5% of the rate of the parent constitutive strain, pac101. seven fluoroacetamide-resistant mutants with low amidase activity gave rise to secondary mutant strains on succinate+butyramide plates. one appeared to be an 'up-promotor' mutant and synthesized amidase at a high rate. this mutant, pac433, was not stimulated by cyclic-amp and was much less sensitive to catabolite repre ...	1975	170366
mapping rnase t1-resistant oligonucleotides of avian tumor virus rnas: sarcoma-specific oligonucleotides are near the poly(a) end and oligonucleotides common to sarcoma and transformation-defective viruses are at the poly(a) end.	the large rnase t1-resistant oligonucleotides of the nondefective (nd) rous sarcoma virus (rsv): prague rsv of subgroup b (pr-b), pr-c and b77 of subgroup c; of their transformation-defective (td0 deletion mutants: td pr-b, td pr-c, and td b77; and of replication-defective (rd) rsv(-) were completely or partially mapped on the 30 to 40s viral rnas. the location of a given oligonucleotide relative to the poly(a) terminus of the viral rnas was directly deduced from the smallest size of the poly(a) ...	1975	170411
[characteristics and types of clostridium perfringens derived from various animals].		1975	170433
[a cell-line with 27 chromosomes in a human acute leukemia (author's transl)].	chromosomal analysis of the bone-marrow aspirate of a five years old girl suffering acute leukemia revealed a cell-line carrying 27 chromosomes. banding by controlled heating denaturation showed that, in these cells, all chromosomes are haploid, except chromosomes: x, 10, 18, 21. this cell-line, not seen during remission, was found during relapse, in addition to another one with 54 chromosomes. the caryotype of this last clone corresponded to the duplication of the chromosome set found in the fi ...	1975	170589
effect of cellular desialylation on choline high affinity uptake and ecto-acetylcholinesterase activity of cholinergic neuroblasts.		1975	172090
effects of indomethacin on intestinal secretion, prostaglandin e and cyclic amp: evidence against a role for prostaglandins in cholera toxin-induced secretion.	the effects of indomethacin on intestine mucosal camp, intestinal fluid secretion, and mucosal and fluid pge were studied in rabbits in vivo following challenge with cholera toxin. indomethacin had no effect on cholera toxin-induced fluid secretion or camp accumulation. inhibition of pge synthesis was achieved by the administration of two but not one injection of indomethacin. these studies provide evidence against a role for pge in mediating cholera toxin-induced secretion and point out the nee ...	1975	172982
ultrastructural myocardial changes produced by viruses.	some of the ultrastructural pathological alterations in the myocardium produced by viral infections with members of the picornavirus group are described. these alterations varied from mild to severe, with necrosis. in animals infected with coxsackie b1 virus and emc virus, readily identifiable viral crystals were frequently found in association with the myocardial lesions by means of electron microscopy. the electron microscope made it possible to study vary early myocardial changes which were n ...	1975	172990
discussion: nigrostriatal projections and the "dopamine report".		1975	173061
sexual differentiation in aspergillus nidulans: the requirement for manganese and the correlation between phosphoglucomutase and the synthesis of reserve material.	aspergillus nidulans was completely devoid of fruit bodies when grown on manganese deficient cultures. this result was shown earlier to be due to a lack of alpha-1,3 glucan in the cell wall. several enzymes of carbon and nitrogen metabolism were investigated in an attempt to explain the absence of this reserve material. synthesis of glucose-6-phosphate dehydrogenase, phosphoglucoisomerase and aldolase, were not strongly affected by manganese deficiency. however, phosphoglucomutase showed only 60 ...	1975	173248
biosynthesis and secretion of testosterone by adrenal tissue from the north american opossum, didelphis virginiana, and the effects of tropic hormone stimulation.		1975	173619
proceedings: phosphatidylinositol kinase activity in rat parotid secretory granules.		1975	173677
unique virus-related dna sequences in sheep progressive pneumonia lung.	hybridization studies with [3h]-cdna of progressive pneumonia, maedi and visna viruses demonstrate that lung dna from sheep afflicted with progressive interstitial pneumonia possesses virus-related sequences not present in normal sheep lung dna.	1975	173794
phosphoprotein phosphatase activity in the thyroid.	phosphoprotein phosphatase activity in the calf thyroid was found in various subcellular fractions. the relative amount in each fraction varied according to the substrate used: the 500g fraction had the highest specific activity when protamine was used, while the 5000g fraction was highest when histone was used. triton x-100 tended to increase activity in all the particulate fractions, the greatest change being found in the 105,000g pellet. deae chromatography of the 105,000 g supernatant resolv ...	1975	174136
substrate specificity of lecithin:cholesterol acyltransferase. esterification of desmosterol, b-sitosterol, and cholecalciferol in human plasma.	desmosterol and beta-sitosterol were esterified when incubated with normal human plasma. the initial rate of demosterol esterification was 1.7 times faster, and that of beta-sitosterol 0.4 times slower, than the esterification rate of cholesterol. these ratios were found to be almost the same when plasma from different normal individuals was tested. plasma from a patient with familial lecithin:cholesterol acyltransferase deficiency did not esterify any of the sterols. the esterification of desmo ...	1975	174187
[some physicochemical properties of the dysenteric therapeutic--prophylactic newcastle phages h-17 and h-18 (author's transl)].	some physico-chemical properties of dysentery therapeutic-prophylactic newcastle-phages h-17 and h-18 were studied. both phages were shown to be resistant to sodium dodecyl sulphate at room temperature. phage h-17 at room temperature was completely inactivated and phage h-18 inactivated by 40% by 1 m sodium hydrochloride. phage h-18 was completely inactivated by 4 m sodium hydrochloride. morphology and sizes of the phages are described. the buoyant density of phage h-17 was found to be 1.497 g/c ...	1975	174322
[testing the spontaneous impulse activity of an impulse evoked by the synaptic route].		1975	174339
cat leukemia and its viruses.		1975	174410
progesterone in the uterus. v. correlation of the in vitro progesterone metabolism with the progesterone binding in rat uterus.	incubations of rat uterine segments with varying 3h-progesterone concentrations were performed to study the hormone uptake by the tissue. the radioactivity of the uterus and the nutrient medium were plotted in form of a scatchard plot. additionally, the binding capacity of the uterine cytosol was measured. in both systems, the hormone was found to be associated with two components which differ from each other in their association constants. the progesterone metabolism occuring at a hormone conce ...	1975	175525
[ultramorphometry of cells in a hamster embryo fibroblast culture following transformation by rous sarcoma virus].	changes in mitochondria, ergastoplasma and the polyribosomal apparatus of fhe (fibroblasts of hamster embryo) cell culture were studied in the kinetics of their malignification with rous sarcoma virus. considerable alterations were revealed in the organization of protein-synthetising cytoplasmic organells, manifested in the pronounced enhancement of nonspecific protein synthesis and reduction of ergastoplasma. this process starts immediately after the infection and shows a character approximatin ...	1975	175575
studies on the energetic metabolism of shigella flexneri x escherichia coli hybrids devoid of penetration ability. iii. catalase and phosphatase activity.	the catalase and phosphatase activity of avirulent by keratoconjunctival test of guinea pigs lac+, kcp- hybrids that have lost their ability of penetrating in the epithelium, received from virulent strains shigella flexneri (sh. flexneri 222 5a and sh. flexneri m42-43) and donor strains escherichia coli (e. coli k-12, p4x and e. coli h) was investigated. it was established that there is no any dependence between the lost of virulence of the hybrids and the level of the catalase activity. during ...	1975	175614
murine leukaemia virus expression in the akr following thymectomy.	thymectomy effectively prevents the development of spontaneous lymphoma in the akr but how this effect is achieved remains to be determined. one possible mechanism, namely suppression of genomic expression of the oncogenic murine leukaemia virus now seems unlikely since levels of the group specific mulv antigen were in comparision with their sham operated controls unaltered in both neonatally and adult thymectomized akr.	1975	174705
[selective isolation of a crp (cyclic amp receptor protein)-defective mutant by growth suppression by cyclic amp].		1975	175181
a radiometric method for predicting effectiveness of chemotherapeutic agents in murine leprosy.	a simple radiometric method has been developed for evaluating the effect of drugs on the metabolism of m. lepraemurium. the method is based on the measurement of the 14co2 produced through bacterial metabolism of acetate-u-14c. seventeen drugs were tested: bacitracin, cephaloridine, chloramphenicol, cycloserine, dactinomycin, dds, ethionamide, inh, kanamycin, methenamine mandelate, nitrofurantoin, oxacillin, polymyxin b, rifampicin, streptomycin, sulfadimethoxine and vancomycin. the drugs which ...	1975	176120
the humoral immunity status of measles patients.		1975	180748
proceedings: consequences of the two-virus status of the natural mouse lymphatic leukemia viruses.		1975	176133
neurochemical changes in the cat's spinal cord due to orthodromic tetanic stimuli. i: phospholipids.	posttetanic potentiation of monosynaptic reflexes has been used as a paradigm for neuronal plasticity. the explanation for this phenomenon is an increased responsiveness of the synaptic junctions. this would basically require chemical changes of the nervous structures involved. the ventral horn area of the spinal cord was therefore analyzed neurochemically. the determination of the phospholipids revealed an alteration of their composition. sphingomyelin, phosphatidylcholine and phosphatidylinosi ...	1975	178883
tissue specific differences in the 2'-o-methylation of eukaryotic 5.8s ribosomal rna.		1975	178541
natural antibodies in healthy adults.	the serum of 100 adults living in budapest was examined for isohaemagglutinin titre with haemaglutination, for staphylococcal-antitoxin titre with haemolysis inhibition and for bacterial antibody titre against 17 different groups of bacteria with passive haemagglutination. antibody levels in males, except for certain bacterial antibodies, were somewhat lower than in females. the antibody titres, especially in men, decreased gradually from 20 to 50 years of age and were usually lower in rh negati ...	1975	235827
standardisation of the nitroblue-tetrazolium test.	optimal conditions for the nbt-reduction test have been sought. increasing heparin concentrations up to 100 units per ml and a delay in performance of the test, especially when blood specimens are kept at room temperature, resulted in higher values for the nbt index, which then sometimes exceeded the upper limit of normal in healthy people and in uninfected patients. the effect of ph, composition of the buffer, and dye concentration was also investigated. phosphate-buffered saline ph 7-2 contain ...	1975	238038
inhibition of pathogenic enteric bacteria by hyperbaric oxygen: enhanced antibacterial activity in the absence of carbon dioxide.	the antibacterial effects of 24-h exposures to high-pressure oxygen in relation to environmental co(2) were studied at 3 atm absolute (ata) and at 1 ata. eight gram-negative, aerobic and facultatively aerobic, pathogenic enteric bacteria (salmonella typhosa, salmonella paratyphi, salmonella schottmuelleri, shigella dysenteriae, shigella flexneri, proteus vulgaris, pseudomonas aeruginosa, and escherichia coli) were exposed as shallow-broth cultures and agar surface cultures. although broths suppl ...	1975	238466
[development of new types of chemical vaccine for prevention of intestinal infections and problems of their qualitative evaluation. iii. comparative study of immunologic characteristics of experimental antigenic preparations].	as a result of comparative study of the immunological properties and antigenic activity of thyphoid, paratyphoid a and b and sonne and flexner dysentery antigenic preparations obtained by various methods there was revealed a decreased toxicity of the experimental preparations of the tashkent and leningrad institute of vaccines and sera (in comparison with the tryptic antigens) and a considerable advantages of the experimental thyphoid and paratyphoid antigenic preparations by their capacity to i ...	1975	239506
[cellular infiltration of shigella].		1975	765541
[phagocytosis of shigellas with hela cells].		1975	765698
[rectoromanoscopic pictures in dysentery associated with helminthic diseases].		1975	765713
[construction of new types of chemical vaccines for the prevention of intestinal infections, and their qualitative assessment. iv. physical properties and immunological characteristics of the experimental series of chemical vaccines presented for comparative study].	the authors present the results of study of physico-chemical properties of the chemical sorbed monovaccines from the antigens of the causative agents of typhoid fever, paratyphoid a and b and sonne and flexner dysentery obtained by various methods; the results of investigation of their reactogenic properties and immunological activity of limited groups of volunteers also given. the vaccines from the antigens obtained by sparing methods were less reactogenic than the rest experimental and control ...	1975	766526
[characteristics of bacteriophages used in the detection of disturbances in the synthesis of the o-antigen polysaccharide of shigella flexneri].	a study was made of the sensitivity spectra of various strains of sh. flexneri and r-mutants of various chemotypes to bacteriophages used for lysotyping of shigellae and to some bacteriophages specific of the r-mutants of salmonellae and e. coli. as a result of study there was selected and characterized a collection of bacteriophages specific of the s-strains and r-mutants of shigellae of different chemotypes, which could be used in genetic and immunochemical investigations.	1975	766530
immunochemical studies on the serotype of shigella flexneri and its recombinant.	chemical and serologic analysis of polysaccharides of shigella flexneri 2b and its recombinant revealed complete defect of the gene responsible for type ii specificity as a result of recombination. at the same time, function of the gene in the same locus responsible for 7,8 group specificity was partially inhibited. attenuation of group antigen 7,8, associated with partial uncovering of the structure of the basic chain, causes appearance of a distinct 3,4 group antigen. changes of this type in s ...	1975	766721
comparative serologic analysis of lac+ recombinants of serotypes 2a, 2b, 5a and variant y of shigella flexneri.	the serologic structure of lac+ recombinants of 2a, 2b, 5a and var. y serotypes of sh. flexneri was compared. rec. 2a lac+, rec. 2b lac+ and rec. y lac+ were shown to be identified, and rec. 5a lac+ was found to differ from those mentioned in that it was deficient in determinants for 3,4 group antigen complex. furthermore, the paper discusses the presumable genetic mechanisms of the described variability.	1975	766722
[shigellosis in tucumán].	in 731 diarrhea cases studied from january 1971 to june 1973 in tucumán a significant increase of shigellosis in eutrophic children was observed. the frequency of shigella isolations, considering all the enteropathogens found, were: 15,5 %; 13 % and 21,3 % in 1971, 1972 and 1973, respectively (table 1). all the strains of shigella isolated belonged to the shigella flexneri b or shigella sonnei d groups, being the percentage for the former 78 % in 1971; 93 % in 1972 and 77 % in 1973 (table 2). th ...	1975	790480
growth and death of diploid and transformed human fibroblasts.	three possible explanations are presented for the differences in growth potential between human diploid fibroblasts of finite life-span and permanent transformed lines: 1) only diploid cells have a molecular clock mechanism which counts cell divisions prior to senescence. two hypothetical examples of such mechanisms are described; however, the available evidence argues against a clock mechanism for aging in fibroblasts. 2) cells become committed with a given probability to a slow buildup in prot ...	1975	1088944
[mixed epidemic of typhoid fever and shigellosis].		1975	1089349
antimicrobial resistance of shigellae isolated in michigan.	patterns of antimicrobial resistance were studied for 213 strains of shigellae isolated in rural and urban areas of michigan by quantitative techniques: 66% of these organisms were resistant to ampicillin, tetracycline, cephalexin, or chloramphenicol or had multiple resistance to various combinations of these antibiotics. the incidence of resistant organisms was higher in the detroit-wayne county area, which is the most urban part of the state. nalidixic acid and oxolinic acid were noted to be q ...	1975	1089819
observations on the serologic changes in the recombinants in shigella flexneri serotype 4a.	studies on the antigenic composition of 84 diagnostic strains of s. flexneri serotype 4a and their lac+ recombinants from a cross with e. coli hfrc were carried out. considerable differentiation of agglutination reaction was found both in original material and in recombinants. an interesting group included recombinants which completely lost their capability to agglutinate with sera specific for type and group antigens and preserved only the capability to agglutinate in the polyvalent serum of s. ...	1975	1090112
pathophysiology of shigella diarrhea in the rhesus monkey: intestinal transport, morphological, and bacteriological studies.	in contrast to the "toxigenic diarrheas" caused by vibrio cholerae and escherichia coli, the site and mechanism of fluid loss in shigellosis are unknown. the occurrence of watery diarrhea in shigellosis suggests involvement of the small bowel. therefore, jejunal, ileal, and colonic water and electrolyte transport was studied in shigella flexneri 2a-infected monkeys. infected animals fell into three groups: dysentery alone, diarrhea alone, or diarrhea and dysentery. in controls, net water, sodium ...	1975	1090480
occurrence of the bacteriophage lambda receptor in some enterobacteriaceae.	in escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ...	1975	1090748
live versus killed bacterial vaccines.		1975	1090808
phage conversion of shigella flexneri group antigens.	a temperate phage, designated sf6, has been isolated from shigella flexneri 3a. characterization of sf6 revealed that it possesses the capacity for converting the s. flexneri 3,4 group antigen complex to group factor 6. serological studies and chemical analysis of lipopolysaccharide from converted strains suggest that group factor 6 is a reflection of an acetylation of the preexisting 3,4 antigen complex. evidence is provided that the 3,4 group antigen complex functions, at least in part, as a c ...	1975	1091548
detection of a leukocytic endogenous mediator-like mediator of serum amino acid and zinc depression during various infectious illnesses.	serum samples from patients with many different kinds of infection were shown to contain a substance characteristic of leukocytic endogenous mediator. generalized bacterial infections produced more leukocytic endogenous mediator than did localized ones; viral infections produced very little. in typhoid fever, mediator concentrations increased before the onset of illness.	1975	1091555
[retroperitoneal, mediastinal and subcutaneous emphysema and bacillary dysentery].		1975	1092028
[sensitivity of different strains of e. coli and shigella to the inhibitory action of ploskirev's bactoagar].	a study was made of the sensitivity of 190 strains of e. coli and 107 strains of shigellae of different serological types to the inhibitory action of ploskirev's bactoagar on the capacity of these bacteria to form colonies. the strains under study proved to be nonhomogenous in this respect: between different strains of e. coli there were revealed 10-, 100- and even 1000-fold differences by this property; the differences between shigellae strains were less marked--in over 90% of shigellae strains ...	1975	1092090
[genetic control of the ability of sh. flexneri to produce a lethal effect on macrophages. i. study of the possible extrachromosomal nature of the cyt+-determinant].	it was shown that cyt+-determinant could not be eliminated when the sh. flexneri cultures were treated with ethidium bromide under the regimen providing the elimination of the f'lac-factor in a part of shigellae population. the cytotoxic sh. flexneri strains which acquired the r-factor transmitted the multiple drug resistance to the cyt minus -strain of sh. flexneri, but not the cyt+-properties. there was found no correlation between the cytoxicity of the sh. flexneri strains and their capacity ...	1975	1092094
[polyamines in species of microorganisms of the intestinal group].	a study was made of polyamines (putrescine, spermidine and spermin) in various representatives of the enterobacteriaceae family--e. coli, sh, sonnei, sh. flexneri and s. typhi abdominalis. all the strains under study contained putrescine and spermidine, and many shigella and salmonella strains had spermin in addition. there were significant differences in the quantitative content of polyamines in the individual species. by the ratio of nitrogen of polyamine to phosphorus of nucleic acid it is po ...	1975	1092098
[microbial antagonism and its role in the development of infection (literature review)].		1975	1092099
[the role of the ability of sh. flexneri to synthesize pili of the common type in the development of dysenteric infections].	hep-2 epithelial cells infected with isogenic sh. flexneri strains characterized by capacity to synthesize common pili (confirmed by electron microscopy) were studied. it was shown that although pili promoted an earlier adhesion of shigellae to the cells, they were not very significant for the penetration and intracellular development of dysentery bacilli in the epithelium. the use of bacteria labeled with 3h-glucose offers a possibility of an objective rapid and precise determination of the cap ...	1975	1092108
transfer of e1 and v colicinogenic factors to shigella flexneri.	from escherichia coli strains, cole1-ml and colv-k94 factors were transferred to a virulent shigella flexneri 2a strain at 1-2% frequency. s. flexneri colv+ and cole1+v+ produced col- segregants. the cole1 factor was stably incorporated into s. flexneri. the colv+ culture lost its virulence to the guinea pig eye.	1975	1092133
shigellosis at sea: an outbreak aboard a passenger cruise ship.	between june 23 and june 30, 1973, 90% of 650 passengers and at least 35% of 299 crew members experienced a diarrheal illness during a 7-day caribbean cruise aboard a passenger cruise liner. symptoms were consistent with shigellosis, and shigella flexneri 6, boyd 88 biotype, was isolated from rectal swabs taken from 8 to 35 ill passengers and 33 of 294 crew members. epidemiologic evidence incriminated the ship's water, including ice, as the probable vehicle of transmission, and elevated coliform ...	1975	1092155
[on flucloxacillin sensitivity determination by the disc method (author's transl)].		1975	1092891
undecaprenol phosphate, the endogenous acceptor of glucose from udpglucose in shigella flexneri.		1975	1093344
superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1.	the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ...	1975	1094073
transmissible substrate-utilizing ability in enterobacteria.	three of 152 strains of escherichia coli transmitted their ability to utilize sucrose (sac+) to other strains by conjugation. the transfer factor of one of them and of a sac+ salmonella thompson strain was thermosensitive. the raffinose-utilizing ability of 27 of 163 e. coli strains was also transmissible. transmissible raffinose-utilizing ability was a feature of porcine enterpathogenic strains possessing the k88 antigen. the determinants controlling raffinose utilization (raf) and k88 antigen ...	1975	1094091
bacteremia in suckling rabbits after oral challenge with vibrio parahaemolyticus.	vibrio parahaemolyticus, a halophilic marine enteropathogen, produces diarrhea in man after ingestion of contaminated seafood. only strains capable of producing beta-hemolysis (kanagawa-positive strains) are enteropathogenic. yet the majority of marine isolants are nonhemolytic and kanagawa negative. studies were initiated in suckling rabbits in an attempt to elucidate pathogenetic mechanisms. fasting animals were infected orally with kanagawa-positive and kanagawa-negative strains of v. parahae ...	1975	1095481
role of immunoglobulins in protection against shigella-induced keratoconjunctives.	various immunoglobulin preparations were tested for their ability to protect guinea pig eyes from infection by a virulent strain of shigella flexneri. secretory immunoglobulin a was effective in delaying or preventing keratoconjunctivitis in eight guinea pigs when it was used to precoat the organism, and was also placed in the eye with the inoculum. neither immunoglobulin g nor immunoglobulin m gave any protection when used in the same way. protection by secretory immunoglobulin a appeared to be ...	1975	1095483
diarrhoea: a traveller's tale.	travellers' diarrhoea is a result of travelling overseas. proper diagnosis can only be made when a full microbiological investigation is carried. a case due to shigella flexneri is described.	1975	1095981
studies on the energetic metabolism of shigella flexneri times escherichia coli hybrids devoid of penetration ability i. glycolysis.	the aerobic and anaerobic (in presence of kcn) glycolysis is studied of avirulent hybrids of shigella flexneri according to the keratoconjunctivitis test of sereny with genetic characteristics lac-+kcp-minus devoid of penetration ability. it is established that lac-+kcp-minus hybrids which have lost their ability to penetrate the cells due to replacement of kcp-gene of the chromosome of donor strain e. coli k-12 p4 times, are characterized with a steep decrease of their glycolitic activity in bo ...	1975	1096507
shigellosis in a neonate: successful treatment with an oral elemental diet.		1975	1097146
shigella strains associated with infantile diarrhea in the kaohsiung area.	in 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ...	1975	1097211
chronic vulvovaginitis in children due to shigella flexneri.	although previous reports have implicated shigella flexneri in resistant or chronic cases of vulvovaginitis in children, no authors have described the clinical findings of this condition. the report presents four cases of persistent vulvovaginitis in prepubertal indian girls from different reservation communities in arizona. s. flexneri was isolated in pure culture from the vaginal discharge of each patient. all four cases were characterized by a prolonged vaginitis with a bloody, purulent disc ...	1975	1098002
studies on the energetic metabolism of shigella flexneri and escherichia coli hybrids devoid of penetration ability. ii. oxygen uptake and dehydrogenase activity.	oxygen uptake and dehydrogenase activity are studied with lac+ kcpminus hybrids of shigella flexneri, being avirulent to the eyes of guinea pigs, because of having lost ability for penetration in epithelial cells. these strains were obtained by hybridization of the virulent strain shigella flexneri 222 5 a with the hfr strain escherichia coli k-12 p4x. it is established that lac+ kcp minus hybrids are characterized by significant decrease of respiratory activity. this decrease is outlined as a t ...	1975	1098322
[the anodic-moving thermolabile antigen (ata) of gram-negative bacteria: its occurrence in rough mutants of shigella flexneri and escherichia coli(author's transl)].	the thermolabile antigen (ata) moving to the anode, discovered by us (9) and also described by larsson et al. (8), could be detected in ra-, rb-, re- and rd-mutants of sh. flexneri and, in smaller amounts, in rd- and re- mutants of e. coli o8:k27:h. so it proves to be different from kunin's common antigen (7). our results lead to the conclusion that ata is located in a more inner part of the bacterial cell wall and is fixed by noncovalent linkages.	1975	1098323
[prevalence of biochemical variants of shigella flexneri 6 in poland].		1975	1101312
epidemiologic investigation of an outbreak of shiga bacillus dysentery in an island population.	an epidemic of dysentery broke out in st. martin island during may through july 1973. the epidemic was caused by shigella dysenteriae type 1. the dysentery could not be controlled by conventional antibiotics and other antidysenteric drugs. the average attack rate was 32.9%. the age specific attack rate was highest in the age group 1-4 years (52.2%). the attack rates were higher in smaller families. the rates were not greatly different amongst people using different sources of water. the overall ...	1975	1101385
hemagglutination test in 150 children with diarrhoea and 100 normal children.		1975	1102449
r-factors in urinary tract infection.		1975	1104976
[comparative study of the preventive properties of sera obtained by immunization with shigella flexneri strains of varying degrees of virulence].		1975	1106084
[study of the sensitivity of shigella to ectericide].		1975	1106086
[intracellular parasitism of shigella in patients with dysentery].	bioptic specimens of the mucosa of the distal portion of the colon in patients with dysentery, caused by flexner and sonne shigellas, were studied by luminescent-serological and electron-microscopy methods. in the cells with unchanged ultrastructure no shigellas were detected. intracellular localization of shigellas was observed only in cases of deep irreversible alterations in the ultrastructure of the cells.	1975	1106366
[morphologic characteristics of lysogenic phages with conversion activity in shigella flexneri].	the morphology of three lysogenic bacteriophages which induce antigenic conversion in various shigella flexneri serotypes (ii and v type antigen and 7.8 group antigen) has been investigated. a quite different morphology appeared with respect to that of salmonella.	1975	1107127
[biochemical and genetic characteristics of enteropathogenic escherichia coli and shigella. v. the biological properties of auxotrophic mutants of shigella flexneri 2a and of escherichia coli serogroup 0124:k72].		1975	1108515
[genetic control of the capacity of sh. flexneri to exert a lethal effect on macrophages. ii. mapping of the cyt-determinant on the shigella chromosome].	crossing experiments showed independence of the genetic determinants controlling the capacity of sh. flexneri to synthesize the primary s-specific side chains (antigen 3,4) and to produce a lethal action on macrophages cultivated in vitro. cytotoxicity was restored only in transmission to the r-strain of shigellae of the capacity to synthesize the antigenic factor 3,4 from the cyt+, but not from the cyt-- donor of sh. flexneri. the determinant responsible for the synthesis of cytotoxin designate ...	1975	1108529
[preparation and properties of some derivatives of methyl-6-amino-6,8 dideoxy-1-thio-d-erythro-alpha-d-galacto octopyranoside].		1975	1108598
changes in the biochemical properties of shigella flexneri la as a result of recombination with escherichia coli k12.	the fermentative properties of recombinants obtained after conjugation between e. coli k12 hfec and s. flexneri la lac phe mutant were investigated. the recombinants showed the antigenic structure of s. flexneri but their biochemical characteristics differed from the properties typical for this genus. the recombinants were found to acquire the ability to ferment several carbohydrates not degraded by the s. flexneri recipient strain.	1975	1108604
[prodigiosin in the overall therapy of dysentery and in the prevention of intrahospital viral respiratory infection in children].	prodigiozan was tested in complex therapy of children with acute dysentery. comparison of clinical symptoms, specific immunogenesis and child sanation periods from shigella in the child groups treated (80) and non-treated (74) with prodigiozan showed that prodigiozan lowered the rate of intrahospital acute respiratory virus infection, provided more favourable dysentery progression, more tensed specific immunity and the patient clearance from shigella.	1975	1108774
subdividing of phage types of shigella flexneri by means of bacteriocins.		1975	1108842
blockade by morphine of acetylcholine release from the caudate nucleus in the mid-pontine pretrigeminal cat.		1975	1111819
free amino acids in human tonsillar tissue.	free amino acids in the tonsils of 20 individuals were measured column chromatographically. those always found in readily detectable amounts included o-phosphoserine, taurine, o-phosphoethanolamine, aspartic acid, hydroxyproline, threonine, serine, glutamic acid, proline, glycine, alanine, alpha-amino-n-butyric acid, valine, cystine, methionine, isoleucine, leucine, tyrosine, phenylalanine, ornithine, gamma-amino-butyric acid, lysine, histidine, and arginine. results were compared for three clin ...	1975	1112054
renal circulatory responses to general anaesthesia in the rabbit: studies using radioactive microspheres.	1. total renal blood flow and its cortical distribution were measured by the radioactive microsphere technique in conscious rabbits and after anaethesia with pentobarbitone, chloralose-urethane or ether. 2. pentobarbitone anaesthesia caused a fall of 26% in total renal blood flow, of 26% in superficial cortical flow, and of 24% in deep cortical flow. sodium excretion rate fell by 33%. 3. chloralose-urethane anaesthesia caused no change in total or regional renal blood flow, or in sodium excretio ...	1975	1112081
endocrine responses to insulin hypoglycaemia in the young calf.	1. variations in the output of glucocorticoids and catecholamines from the right adrenal gland, in response to insulin hypoglycaemia, have been investigated in calves 2-5 weeks after birth. these have been correlated with changes in the concentration of glucocorticoids and glucagon in arterial plasma. 2. moderate hypoglycaemia for a limited period (0-1 u. insulin/kg), elicited a prompt increase in steroid output from the adrenal gland followed by a significant rise in plasma glucagon concentrati ...	1975	1133779
significance of severity of coronary arterial stenosis: metabolic studies and correlation with hyperemic response.		1975	1134082
essential dietary amino acids for growth of larvae of the yellow mealworm, tenebrio molitor l.	larvae of the yellow mealworm, tenebrio molitor l., have been used to evaluate nutritional quality of proteins and protein isolates. however, such investigations have been complicated by lack of knowledge of dietary requirements of the larvae. to determine essential dietary amino acids for growth of tenebrio molitor, single amino acids were deleted from the amino acid mixture of the diet. diets were maintained isonitrogenous with supplementary glycine and, in the case of deleted glycine, with gl ...	1975	1142013
proceedings: cell-wall composition of aerobic cutaneous "diphtherios" organisms.		1975	1142405
aggregation states and catalytic properties of the multienzyme complex catalyzing the initial steps of pyrimidine biosynthesis in rat liver.	glutamine-dependent carbamoyl-phosphate synthetase was purified about 2100-fold from the cytosol of rat liver using 30% (v/v) dimethyl sulfoxide and 5% (w/v) glycerol as stabilizers. throughout the purification, aspartate transcarbamylase and dihydroorotase, the second and third enzymes of pyrimidine biosynthesis, were copurified with the synthetase. these three enzymes sedimented as a single peak with a sedimentation coefficient of 27 s in sucrose gradients containing the stabilizers, indicatin ...	1975	1148171
the detection of specific igm antibodies following infection with rubella virus.	a gel filtration technique using sephadex g-200 has been used for the detection of specific igm in sera from (a) 45 cases of clinical rubella in which diagnostic rises of rubella haemagglutination-inhibiting (hai) antibody could be demonstrated; (b) 70 cases with clinical evidence of rubella in which a rising titre could not be demonstrated because the first serum sample already had high titre hai antibodies; and (c) 100 patients in whom rubella was not suspected. the results indicate that the h ...	1975	1150889