Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| olive mill waste extracts: polyphenols content, antioxidant, and antimicrobial activities. | natural polyphenols extracts have been usually associated with great bioactive properties. in this work, we investigated in vitro antioxidant and antimicrobial potential of the phenolic olive mill wastewater extracts (owwe) and the olive cake extracts (oce). using the folin ciocalteux method, owwe contained higher total phenol content compared to oce (8.90 ± 0.728 g/l versus 0.95 ± 0.017 mg/g). the phenolic compounds identification was carried out with a performance liquid chromatograph coupled ... | 2015 | 26693221 |
| enterococcus faecalis septicemia and vertebral osteomyelitis after transrectal ultrasound guided biopsy of the prostate. | transrectal ultrasound guided prostate biopsy (trus) has rarely been associated with disseminated infection, yet the occurrence appears to be increasing. resistance to fluoroquinolones, the most commonly used prophylaxis, is one of the likely causes, with escherichia coli being the most commonly reported cause of these infections. herein we present what is, to our knowledge, the first case of enterococcus faecalis septicemia and vertebral osteomyelitis after trus. previously reported cases of th ... | 2015 | 26682075 |
| genomic sequence of a clinical vancomycin-resistant reference strain, enterococcus faecalis atcc 51299. | in this paper, we present a draft genome sequence of a quality control reference strain, enterococcus faecalis atcc 51299 (multilocus sequencing type [mlst] st6), which is sensitive to teicoplanin but resistant to vancomycin. it is used in an agar screening test for streptomycin, gentamicin, and vancomycin resistance and the resistance marker vanb. | 2015 | 26679597 |
| the effect of addition of an eps degrading enzyme with and without detergent to 2% chlorhexidine on disruption of enterococcus faecalis biofilm: a confocal laser scanning microscopic study. | enterococcus faecalis is one of the most commonly occurring organisms retrieved from root canal treated teeth that show refractory apical periodontitis. though it is well known that the ability of e. faecalis to form a matrix-encased biofilm contributes to its pathogenicity, the role of extracellular dextran and dna in biofilm formation and its effect on the susceptibility of the biofilm to chlorhexidine remains poorly understood. it was hypothesized that the addition of an extracellular polymer ... | 2015 | 26675655 |
| an in vitro evaluation of antimicrobial activity of five herbal extracts and comparison of their activity with 2.5% sodium hypochlorite against enterococcus faecalis. | sodium hypochlorite is the most widely used irrigant in endodontic practice, but it has various disadvantages. literature has shown that herbal products such as propolis, azadirachta indica (ai), triphala, curcuma longa, and morinda citrifolia (mc) possess good antimicrobial properties and thus can be used as potential endodontic irrigants. | 2015 | 26672425 |
| anti-microbial efficacy of allium sativum extract against enterococcus faecalis biofilm and its penetration into the root dentin: an in vitro study. | sodium hypochlorite (naocl) has long been the most preferred root canal irrigant in endodontic treatment, but besides being an effective anti-microbial agent, it is highly cytotoxic. thus, a search for an alternative herbal irrigant which would be more biocompatible but equally effective led to this study. | 2015 | 26672416 |
| hydrothermally treated chitosan hydrogel loaded with copper and zinc particles as a potential micronutrient-based antimicrobial feed additive. | large-scale use of antibiotics in food animal farms as growth promoters is considered as one of the driving factors behind increasing incidence of microbial resistance. several alternatives are under investigation to reduce the amount of total antibiotics used in order to avoid any potential transmission of drug resistant microbes to humans through food chain. copper sulfate and zinc oxide salts are used as feed supplement as they exhibit antimicrobial properties in addition to being micronutrie ... | 2015 | 26664989 |
| degree of bacterial microleakage at the implant-abutment junction in cone morse tapered implants under loaded and unloaded conditions. | different results have been reported on the internal colonization of cone morse connections under in vitro dynamic loading. the aim of the present in vitro study was to evaluate the bacterial leakage in cone morse implant-abutment connections, both under loaded and unloaded conditions. | 2015 | 26660625 |
| tricuspid valve endocarditis complicated by mobitz type ii heart block - a case report and literature review. | we present a case of a middle-aged male who manifested with low-grade fever and lower back pain. mri and bone scan of the spine were suggestive of vertebral osteomyelitis. blood cultures were persistently positive for enterococcus faecalis and echocardiogram revealed tricuspid valve endocarditis. there was no history of iv drug use and urine toxicology was negative. ekg showed mobitz type ii av block and a transesophageal echocardiogram revealed no valve ring or septal abscesses. the heart block ... | 2015 | 26653699 |
| antibacterial and toxic effect of hydrogen peroxide combined with different concentrations of chlorhexidine in comparison with sodium hypochlorite. | hydrogen peroxide (h2o2) has been suggested to be used in sequence or in combination with chlorhexidine (chx) to enhance the antibacterial activity against enterococcus faecalis, but there is no research in the literature on the safety and effectiveness of this irrigation protocol. | 2015 | 26636124 |
| in vitro comparison of antimicrobial effectiveness of qmix and other final irrigants in human root canals. | final root canal irrigation stands as an effective strategy for eliminating the dentin infection. this study aimed to investigate and compare the antibacterial efficacy of qmix and other four final irrigation regimens in reducing enterococcus faecalis within human root canals. single-canal human teeth contaminated with e. faecalis for 4 weeks were prepared chemomechanically with sodium hypochlorite (naocl). then, the teeth were randomly assigned into six groups according to the final irrigation ... | 2015 | 26631907 |
| cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in gram-positive bacteria. | cyclic peptides are commonly used as quorum-sensing autoinducers in gram-positive firmicutes bacteria. well-studied examples of such molecules are thiolactone and lactone, used to regulate the expression of a series of virulence genes in the agr system of staphylococcus aureus and the fsr system of enterococcus faecalis, respectively. three cyclodepsipeptides ws9326a, ws9326b and cochinmicin ii/iii were identified as a result of screening actinomycetes culture extracts for activity against the a ... | 2015 | 26149266 |
| synergistic effect of 2% chlorhexidine combined with proteolytic enzymes on biofilm disruption and killing. | to investigate the dynamics of a disinfection regimen using 1% trypsin and 1% proteinase k in combination with 2% chlorhexidine (with or without ultrasonics) using a nutrient-stressed endodontic multispecies model biofilm. | 2015 | 25482847 |
| isolation of alkaline-tolerant bacteria from primary infected root canals. | alkaline-tolerant bacteria in primary infected root canals could have enhanced survival capacity against antimicrobials commonly used in root canal treatment. the aims of this study were to isolate and characterize alkaline-tolerant bacteria before endodontic treatment (s1), after chemomechanical root canal preparation (s2), and after calcium hydroxide dressing (s3). | 2015 | 25638530 |
| polymicrobial q fever and enterococcal aortic prosthetic valve endocarditis with aortic root abscess. | polymicrobial endocarditis is uncommon. we present a case of polymicrobial endocarditis caused by enterococcus faecalis and coxiella burnetii and review previous cases of polymicrobial endocarditis involving coxiella burnetii. testing for q fever should be considered in any patient with endocarditis living in an endemic area. | 2015 | 25988443 |
| a novel method for screening of potential probiotics for high adhesion capability. | to screen for potential probiotics with high adhesion capability, a chemostat model-based cultured human feces and denaturing gradient gel electrophoresis methods were applied, and the adhesion capability of the isolates was evaluated in vitro and in vivo. lactobacillus plantarum (hm218749), lactobacillus reuteri (eu547310), and enterococcus faecalis (hm218543) were isolated from the slime on the chemostat wall, as these organisms could grow better at 37°c in an anaerobic environment and could r ... | 2015 | 25912863 |
| effectiveness of probiotic therapy for the prevention of relapse in patients with inactive ulcerative colitis. | to evaluate the effectiveness of probiotic therapy for suppressing relapse in patients with inactive ulcerative colitis (uc). | 2015 | 26019464 |
| early colonizing escherichia coli elicits remodeling of rat colonic epithelium shifting toward a new homeostatic state. | we investigated the effects of early colonizing bacteria on the colonic epithelium. we isolated dominant bacteria, escherichia coli, enterococcus faecalis, lactobacillus intestinalis, clostridium innocuum and a novel fusobacterium spp., from the intestinal contents of conventional suckling rats and transferred them in different combinations into germfree (gf) adult rats. animals were investigated after various times up to 21 days. proliferative cell markers (ki67, proliferating cell nuclear anti ... | 2015 | 25012905 |
| mutations associated with reduced surotomycin susceptibility in clostridium difficile and enterococcus species. | clostridium difficile infection (cdi) is an urgent public health concern causing considerable clinical and economic burdens. cdi can be treated with antibiotics, but recurrence of the disease following successful treatment of the initial episode often occurs. surotomycin is a rapidly bactericidal cyclic lipopeptide antibiotic that is in clinical trials for cdi treatment and that has demonstrated superiority over vancomycin in preventing cdi relapse. surotomycin is a structural analogue of the me ... | 2015 | 25941217 |
| an alkaline phosphatase reporter for use in clostridium difficile. | clostridium difficile is an anaerobic, gram-positive pathogen that causes severe gastrointestinal disease in humans and other mammals. c. difficile is notoriously difficult to work with and, until recently, few tools were available for genetic manipulation and molecular analyses. despite the recent advances in the field, there is no simple or cost-effective technique for measuring gene transcription in c. difficile other than direct transcriptional analyses (e.g., quantitative real-time pcr and ... | 2015 | 25576237 |
| new role for human α-defensin 5 in the fight against hypervirulent clostridium difficile strains. | clostridium difficile infection (cdi), one of the most common hospital-acquired infections, is increasing in incidence and severity with the emergence and diffusion of hypervirulent strains. cdi is precipitated by antibiotic treatment that destroys the equilibrium of the gut microbiota. human α-defensin 5 (hd5), the most abundant enteric antimicrobial peptide, is a key regulator of gut microbiota homeostasis, yet it is still unknown if c. difficile, which successfully evades killing by other hos ... | 2015 | 25547793 |
| chronic bacterial seminal vesiculitis as a potential disease entity in men with chronic prostatitis. | to investigate bacterial infection in the seminal vesicles by bacteriological examination and radionuclide imaging in men with chronic prostatitis. | 2015 | 25721352 |
| presence of aerobic micro-organisms and their influence on basic semen parameters in infertile men. | urogenital tract infections in males are one of the significant etiological factors in infertility. in this prospective study, 72 patients with abnormal semen parameters or any other symptoms of urogenital tract infection were examined. semen analysis according to the who 2010 manual was performed together with microbial assessment: aerobic bacteria culture, chlamydia antigen test, candida culture, ureaplasma and mycoplasma-specific culture. in total, 69.4% of semen samples were positive for at ... | 2015 | 25209133 |
| use of a dissolved oxygen microsensor for assessing the viability and thickness of microbial biofilm on root surfaces. | to evaluate the use of a dissolved oxygen microsensor (doms) for assessing the viability and thickness of microbial biofilms on the apical external surface of contaminated human tooth roots. | 2015 | 24942082 |
| in vitro and ex vivo antimicrobial efficacy of nano-mgo in the elimination of endodontic pathogens. | the use of metal oxide nanoparticles has attracted lots of attention, mostly because of their promising antimicrobial activity along with their biocompatibility with mammalian cells. this study aims to investigate the in vitro and ex vivo antimicrobial efficiency of nano-magnesium oxide (mgo) aqueous solution against endodontic pathogens. | 2015 | 24859291 |
| microbial community in persistent apical periodontitis: a 16s rrna gene clone library analysis. | to characterize the microbial composition of persistent periapical lesions of root filled teeth using a molecular genetics approach. | 2015 | 25088120 |
| evaluation of cytotoxicity, antimicrobial activity and physicochemical properties of a calcium aluminate-based endodontic material. | a calcium aluminate-based endodontic material, endobinder, has been developed in order to reduce mta negative characteristics, preserving its biological properties and clinical applications. | 2015 | 24626250 |
| isolation and taxonomic identity of bacteriocin-producing lactic acid bacteria from retail foods and animal sources. | bacteriocin-producing (bac⁺) lactic acid bacteria (lab) were isolated from a variety of food products and animal sources. samples were enriched in de man, rogosa, and sharpe (mrs) lactocilli broth and plated onto mrs agar plates using a "sandwich overlay" technique. inhibitory activity was detected by the "deferred antagonism" indicator overlay method using listeria monocytogenes as the primary indicator organism. antimicrobial activity against l. monocytogenes was detected by 41 isolates obtain ... | 2015 | 27682080 |
| antimicrobial and cytotoxic activity of ferula gummosa plant essential oil compared to naocl and chx: a preliminary in vitro study. | the usage of medicinal plants as natural antimicrobial agents has grown in many fields including dental medicine. the aim of this in vitro study was three-fold: (i) to determine the chemical compositions of the ferula gummosa essential oil (fgeo), (ii) to compare the antimicrobial efficacy of the oil with sodium hypochlorite (naocl) and chlorhexidine (chx), (iii) to assess the toxic behavior of fgeo in different concentrations compared to 5% naocl and 0.2% chx. | 2015 | 25671213 |
| performance evaluation of a dna chip assay in the identification of major genitourinary pathogens. | to prevent the recurrence of genitourinary infections and to reduce the risks of their complications, accurate and rapid diagnosis are required. stdetect® chip is a dna chip which allows for the simultaneous detection of 13 major genitourinary pathogens in a single vaginal swab or urine specimen. we evaluated the analytical performance of the stdetect® chip for detecting target pathogens that commonly cause genitourinary infections. | 2015 | 25533217 |
| syntheses, structures, and antimicrobial activity of new remarkably light-stable and water-soluble tris(pyrazolyl)methanesulfonate silver(i) derivatives of n-methyl-1,3,5-triaza-7-phosphaadamantane salt - [mpta]bf4. | two new silver(i) complexes of formula [ag(mpta)4](tpms)4(bf4) (1) and [ag(tpms)(mpta)](bf4) (2) (mpta = n-methyl-1,3,5-triaza-7-phosphaadamantane cation, tpms = tris(pyrazol-1-yl)methanesulfonate anion) have been synthesized and fully characterized by elemental analyses, (1)h and (31)p{(1)h} nmr, esi-ms, and ir spectroscopic techniques. the single-crystal x-ray diffraction study of 1 discloses a noncoordinated nature of the tpms species, existing as counterions around the highly charged metal c ... | 2015 | 25531979 |
| utilization of blood cultures in danish hospitals: a population-based descriptive analysis. | this national population-based study was conducted as part of the development of a national automated surveillance system for hospital-acquired bacteraemia and ascertains the utilization of blood cultures (bcs). a primary objective was to understand how local differences may affect interpretation of nationwide surveillance for bacteraemia. from the danish microbiology database, we retrieved all bcs taken between 2010 and 2013 and linked these to admission data from the national patient registry. ... | 2015 | 25658520 |
| adenosine tri-phosphate (atp)-based cleaning monitoring in health care: how rapidly does environmental atp deteriorate? | ensuring cleaning compliance of housekeeping staff is critical to ensure adequate application of surface disinfectants. adenosine triphosphate (atp) testing has been recommended as a way to monitor cleaning compliance; however, little is known about the stability of atp on environmental surfaces. | 2015 | 25794441 |
| the in vitro antimicrobial activity of cymbopogon essential oil (lemon grass) and its interaction with silver ions. | it is well known that cymbopogon (lemon grass) essential oil exhibits antimicrobial activity while the efficacy of silver ions as a disinfectant is equally well reported. | 2015 | 26055131 |
| the efficacy of photodynamic therapy and sodium hypochlorite in root canal disinfection by a single-file instrumentation technique. | the aim of this in vitro study was to evaluate the efficacy of photodynamic therapy (pdt) and sodium hypochlorite (naocl) in root canal disinfection by a single-file instrumentation technique. | 2015 | 26007242 |
| antimicrobial effect of zataria multiflora extract in comparison with chlorhexidine mouthwash on experimentally contaminated orthodontic elastomeric ligatures. | long-term use of orthodontic appliances and fixation ligatures creates a favorable environment for the accumulation of oral normal microflora and increases the risk of enamel demineralization and periodontal disease. the aim of this study was to compare the antimicrobial effects of zataria multiflora extract and 0.2% chlorhexidine (chx) mouthwash on experimentally contaminated orthodontic elastomeric ligatures. | 2015 | 26005448 |
| composition and antimicrobial activity of euphrasia rostkoviana hayne essential oil. | eyebright, euphrasia rostkoviana hayne (scrophulariaceae), is a medicinal plant traditionally used in europe for the treatment of various health disorders, especially as eyewash to treat eye ailments such as conjunctivitis and blepharitis that can be associated with bacterial infections. some euphrasia species have been previously reported to contain essential oil. however, the composition and bioactivity of e. rostkoviana oil are unknown. therefore, in this study, we investigated the chemical c ... | 2015 | 26000025 |
| localization of the dual oxidase bli-3 and characterization of its nadph oxidase domain during infection of caenorhabditis elegans. | dual oxidases (duox) are enzymes that contain an nadph oxidase domain that produces hydrogen peroxide (h2o2) and a peroxidase domain that can utilize h2o2 to carry out a variety of reactions. the model organism caenorhabditis elegans produces the duox, bli-3, which has roles in both cuticle development and in protection against infection. in previous work, we demonstrated that while certain peroxidases were protective against the human bacterial pathogen enterococcus faecalis, the peroxidase dom ... | 2015 | 25909649 |
| in vitro antimicrobial and anti-endotoxin action of zingiber officinale as auxiliary chemical and medicament combined to calcium hydroxide and chlorhexidine. | this study was conducted in vitro to compare the effectiveness of zingiber officinale as an auxiliary chemical substance followed by placement of different intra-canal medication in removing endotoxins and cultivable micro-organisms from infected root canals. | 2015 | 25892281 |
| immune response profile against persistent endodontic pathogens candida albicans and enterococcus faecalis in vitro. | persistent microorganisms such as candida albicans and enterococcus faecalis might be directly related to endodontic treatment failure. the host response to these microorganisms impairs the reestablishment of intraradicular and periradicular health. | 2015 | 25845887 |
| evaluation of microbial reduction in root canals instrumented with reciprocating and rotary systems. | this in vitro study aimed to evaluate the efficacy of the disinfection of root canal systems carried out with reciproc(tm) and protaper universal(tm) systems using 1% sodium hypochlorite (naocl). | 2015 | 27688413 |
| antimicrobial and antifungal efficacy of spilanthes acmella as an intracanal medicament in comparison to calcium hydroxide: an in vitro study. | repeated endodontic failures are due to pathogens like enterococcus faecalis and candida albicans which are resistant to the common intracanal medicaments like calcium hydroxide (ca[oh]2). | 2015 | 26672426 |
| pyrrolocin a, a 3-decalinoyltetramic acid with selective biological activity, isolated from amazonian cultures of the novel endophyte diaporthales sp. e6927e. | natural products remain an important source of new therapeutics for emerging drug-resistant pathogens like candida albicans, which particularly affects immunocompromised patients. a bioactive 3-decalinoyltetramic acid, pyrrolocin a, was isolated from extracts of a novel amazonian fungal endophyte, e6927e, of the diaporthales family. the structure of the natural product was solved using nmr and cd spectroscopy and it is structurally related to the fungal setins, equisetin and phomasetin, which ar ... | 2015 | 26669095 |
| assessment of the antimicrobial activity of few saudi arabian snake venoms. | venoms of two cobras, four vipers, a standard antibiotic and an antimycotic, were evaluated comparatively, as antimicrobials. | 2015 | 26668657 |
| antibacterial, antifungal and antioxidant activity of olea africana against pathogenic yeast and nosocomial pathogens. | olea africana leaves are used by bapedi people to treat different ailments. the use of these leaves is not validated, therefore the aim of this study is to validate antimicrobial properties of this plant. | 2015 | 26577343 |
| antibiofilm and antimicrobial activity of polyethylenimine: an interesting compound for endodontic treatment. | bacteria levels of necrotic teeth are greatly reduced after endodontic treatment procedures but the presence of persisting microorganisms leads to continuous efforts to develop materials with antimicrobial properties. the purpose of the study was to determine the antimicrobial activity of polyethylenimine (pei) against common bacteria and yeasts, regarding planktonic cells and biofilm, and to clarify its antimicrobial mechanism of action through flow cytometry. | 2015 | 26323443 |
| in vitro antimicrobial activity of plants used in traditional medicine in gurage and silti zones, south central ethiopia. | to overcome the escalating problems associated with infectious diseases and drug resistance, discovery of new antimicrobials is crucial. the present study aimed to carry out in vitro antimicrobial analysis of 15 medicinal plant species selected according to their traditional medicinal uses in gurage and silti zones, south central ethiopia. | 2015 | 26283630 |
| effects of a one year reusable contraceptive vaginal ring on vaginal microflora and the risk of vaginal infection: an open-label prospective evaluation. | a contraceptive vaginal ring (cvr) containing nestorone® (nes) and ethinyl estradiol (ee) that is reusable for 1- year (13 cycles) is under development. this study assessed effects of this investigational cvr on the incidence of vaginal infections and change in vaginal microflora. | 2015 | 26267119 |
| composition, cytotoxic and antimicrobial activities of satureja intermedia c.a.mey essential oil. | in this study, the essential oil (eo) constituents from the aerial parts of satureja intermedia c.a.mey were detected by gc and gc/ms. the antimicrobial activity of eo on oral pathogens and its cytotoxicity to human cancer cells were determined by the microbroth dilution method and the crystal violet staining method, respectively. thirty-nine compounds were identified and the main eo constituents were γ-terpinene (37.1%), thymol (30.2%), p-cymene (16.2%), limonene (3.9%), α-terpinene (3.3%), myr ... | 2015 | 26247936 |
| antimicrobial activity and chemometric modelling of south african propolis. | this study reports on the inhibitory and bactericidal properties of 39 south african (sa) propolis samples and three propolis samples from brazil. | 2015 | 26189549 |
| antimicrobial activity of silver and gold in toothpastes: a comparative analysis. | in this study, we compared the antimicrobial activity of identical toothpastes differing only in silver or gold nanoparticles against the activity of one of the common toothpastes containing a chemical active ingredient. we also compared the active concentrations of the toothpastes. | 2015 | 26183852 |
| evaluation of antimicrobial and antifungal efficacy of inter appointment intracanal medicaments against enterococcus and candida albicans: an in vitro study. | microorganisms and their by-products in pulpal and periapical diseases are to be considered as the primary etiological agents of the pulpal necrosis and apical periodontitis. enterococcus faecalis, which is the most common organism isolated from failed root canals, is a gram-positive facultative anaerobe. yeasts can be detected in 7-18% of infected root canals. | 2015 | 26124609 |
| a preliminary investigation on the antimicrobial activity of listerine®, its components, and of mixtures thereof. | listerine® is one of the most popular mouthwashes worldwide and claims to combat harmful bacteria. in the past century, its recipe was changed from an essential oil mouthwash to a five-component mixture (thymol, menthol, eucalyptol, and methyl salicylate dissolved in 27% ethanol). the aim of this study was to get preliminary information about the antimicrobial activities of individual listerine® components and their mixtures. we tested the bacterial strains streptococcus mutans, enterococcus fae ... | 2015 | 26104602 |
| probiotic bifico cocktail ameliorates helicobacter pylori induced gastritis. | to determine the protective effect of triple viable probiotics on gastritis induced by helicobacter pylori (h. pylori) and elucidate the possible mechanisms of protection. | 2015 | 26074694 |
| acarbose treatment affects the serum levels of inflammatory cytokines and the gut content of bifidobacteria in chinese patients with type 2 diabetes mellitus. | the effects of acarbose add-on therapy on gut microbiota and inflammatory cytokines were investigated in chinese patients with type 2 diabetes mellitus (dm). | 2015 | 25327485 |
| [influence of the root canal instrumentation size on the disinfection of intracanal microbe by er:yag laser]. | to evaluate the influence of different root canal instrumentation size on disinfection of intracanal microbe of dental root canal. | 2015 | 27063113 |
| enzymatic elucidation of haemocyanin from kuruma shrimp marsupenaeus japonicus and its molecular recognition mechanism towards pathogens. | haemocyanin is an important non-specific immune protein present in the hemolymph of invertebrates, which have the ability to recognize the microbial pathogens and trigger the innate immune system. in this study, we isolated and purified the haemocyanin using gel filtration chromatography and investigated its microbial recognition mechanism against the invading pathogens. kuruma shrimp marsupenaeus japonicus haemocyanin showed the single band with a molecular weight of 76 kda on sds-page and its ... | 2015 | 25204648 |
| antimicrobial activity of different filling pastes for deciduous tooth treatment. | guedes-pinto paste is the filling material most employed in brazil for endodontic treatment of deciduous teeth; however, the rifocort® ointment has been removed. thus, the aim of this study was to investigate the antimicrobial potential of filling pastes, by proposing three new pharmacological associations to replace rifocort® ointment with drugs of already established antimicrobial power: nebacetin® ointment, 2% chlorhexidine gluconate gel, and maxitrol® ointment. a paste composed of iodoform, ... | 2015 | 25466327 |
| physicochemical and biological properties of oxovanadium(iv), cobalt(ii) and nickel(ii) complexes with oxydiacetate anions. | the potentiometric and conductometric titration methods have been used to characterize the stability of series of vo(iv)-, co(ii)- and ni(ii)-oxydiacetato complexes in dmso-water solutions containing 0-50 % (v/v) dmso. the influence of dmso as a co-solvent on the stability of the complexes as well as the oxydiacetic acid was evaluated. furthermore, the reactivity of the complexes towards superoxide free radicals was assessed by employing the nitro blue tetrazolium (nbt) assay. the biological pro ... | 2015 | 25488702 |
| probiotic potential of lactobacillus strains isolated from sorghum-based traditional fermented food. | sorghum-based traditional fermented food was screened for potential probiotic lactic acid bacteria. the isolates were identified by biochemical, physiological and genetic methods. species identification was done by 16s rrna sequence analysis. the functional probiotic potential of the two lactobacillus species viz., lactobacillus plantarum (lact. plantarum) and lactobacillus pentosus (lact. pentosus) was assessed by different standard parameters. the strains were tolerant to ph 2 for 1 h and resi ... | 2015 | 25666113 |
| optimizing supercritical carbon dioxide in the inactivation of bacteria in clinical solid waste by using response surface methodology. | clinical solid waste (csw) poses a challenge to health care facilities because of the presence of pathogenic microorganisms, leading to concerns in the effective sterilization of the csw for safe handling and elimination of infectious disease transmission. in the present study, supercritical carbon dioxide (sc-co2) was applied to inactivate gram-positive staphylococcus aureus, enterococcus faecalis, bacillus subtilis, and gram-negative escherichia coli in csw. the effects of sc-co2 sterilization ... | 2015 | 25636860 |
| oxidative stress and antibacterial properties of a graphene oxide-cystamine nanohybrid. | oxidative stress can damage proteins, dna, and lipids, and is involved in the progression of many diseases. damage to infected cells caused by oxidative stress is related to increased levels of reactive oxygen species, including hydrogen peroxide. during oxidative stress, hydrogen peroxide levels are often increased and catalase level decreased inside cells. this can lead to the death of skin and other cells. hydrophobic low molecular weight compounds are useful in treating hemorrhagic condition ... | 2015 | 25609960 |
| [bacteria isolated from surgical infections and its susceptibilities to antimicrobial agents--special references to bacteria isolated between july 1982 and march 2012]. | this is an integrated summary of the results obtained from a 3-decade multicenter study on bacteria isolated from surgical infections in japan between july 1982 and march 2012. during the 3-decade study, 11,196 strains were isolated from 4,787 patients consisting of 2,132 patients with primary infection and 2,655 patients with surgical site infection. almost half of the primary infection was peritonitis, which accounted for 42.3%-55.5%. in contrast, most of the surgical site infection was wound ... | 2015 | 26349116 |
| microbiological toxicity of tilmicosin on human colonic microflora in chemostats. | to evaluate the microbiological safety of tilmicosin on human intestinal microflora, four chemostat models of healthy human colonic ecosystems were exposed to tilmicosin (0, 0.436, 4.36, and 43.6 μg/ml) for 7 days. prior to and during drug exposure, three microbiological endpoints were monitored daily including short-chain fatty acids, bacterial counts and macrolide susceptibility. colonization resistance of each community was determined by 3 successive daily challenges of salmonella typhimurium ... | 2015 | 26190303 |
| quantitative profiling of colorectal cancer-associated bacteria reveals associations between fusobacterium spp., enterotoxigenic bacteroides fragilis (etbf) and clinicopathological features of colorectal cancer. | various studies have presented clinical or in vitro evidence linking bacteria to colorectal cancer, but these bacteria have not previously been concurrently quantified by qpcr in a single cohort. we quantify these bacteria (fusobacterium spp., streptococcus gallolyticus, enterococcus faecalis, enterotoxigenic bacteroides fragilis (etbf), enteropathogenic escherichia coli (epec), and afac- or pks-positive e. coli) in paired tumour and normal tissue samples from 55 colorectal cancer patients. we f ... | 2015 | 25751261 |
| antibacterial activity of the venom of heterometrus xanthopus. | heterometrus xanthopus (scorpion) is one of the most venomous and ancient arthropods. its venom contains anti-microbial peptides like hadrurin, scorpine, pandinin 1, and pandinin 2 that are able to effectively kill multidrug-resistant pathogens. the present study was conducted to evaluate the anti-bacterial activity of h. xanthopus venom. six gram-positive and gram-negative bacterial strains were tested against 1/100, 1/10, and 1/1 fractions of distilled water diluted and crude venom. 1/100 and ... | 2015 | 23087515 |
| pathogen distribution and drug resistance in a burn ward: a three-year retrospective analysis of a single center in china. | to investigate the spread of multiple-resistant strain in a burn ward to inform clinical administration of antibiotic drugs, burn wound treatment and decision-making for infection control. a 3-year retrospective analysis was conducted. specimens from wounds, blood, catheter, sputum, urine and stool collected from inpatients of the second affiliated hospital of zhejiang university of medicine between january 1, 2011 and december 31, 2013 were cultured and strains were identified by automatic bact ... | 2015 | 26770555 |
| evaluation of regional antibiograms to monitor antimicrobial resistance in hampton roads, virginia. | we studied recent antibiograms (2010 to 2011) from 12 hospitals in the hampton roads area, virginia, that refer patients to a tertiary-care facility affiliated with eastern virginia medical school. the data was compiled into a regional antibiogram, and sensitivity rates of common isolates from the tertiary-care facility (central) were compared to those of referring hospitals grouped by locale. staphylococcus aureus was the most common gram- positive and e. coli the most common gram- negative org ... | 2015 | 25890362 |
| antibacterial activity of synthetic peptides derived from lactoferricin against escherichia coli atcc 25922 and enterococcus faecalis atcc 29212. | peptides derived from human and bovine lactoferricin were designed, synthesized, purified, and characterized using rp-hplc and maldi-tof-ms. specific changes in the sequences were designed as (i) the incorporation of unnatural amino acids in the sequence, the (ii) reduction or (iii) elongation of the peptide chain length, and (iv) synthesis of molecules with different number of branches containing the same sequence. for each peptide, the antibacterial activity against escherichia coli atcc 25922 ... | 2015 | 25815317 |
| global in vitro activity of tigecycline and comparator agents: tigecycline evaluation and surveillance trial 2004-2013. | the tigecycline evaluation and surveillance trial (test) is a global antimicrobial susceptibility surveillance study which has been ongoing since 2004. this report examines the in vitro activity of tigecycline and comparators against clinically important pathogens collected globally between 2004 and 2013. | 2015 | 25958201 |
| in vitro evaluation of antimicrobial efficacy of extracts obtained from raw and fermented wild macrofungus, lenzites quercina. | in recent time, there is a major concern about antibiotic resistance displayed by some pathogenic microorganisms and this had involved a continuous search for natural antimicrobial products. the phytochemistry as well as antimicrobial activity of extracts obtained from lenzites quercina was investigated. the extracts and purified fractions were, respectively, tested against indicator organisms using agar well diffusion and disc diffusion methods. the quantity of phytochemicals found in the extra ... | 2015 | 26604928 |
| immunostimulatory effects triggered by enterococcus faecalis cect7121 probiotic strain involve activation of dendritic cells and interferon-gamma production. | probiotics can modulate the immune system, conferring beneficial effects on the host. understanding how these microorganisms contribute to improve the health status is still a challenge. previously, we have demonstrated that enterococcus faecalis cect7121 implants itself and persists in the murine gastrointestinal tract, and enhances and skews the profile of cytokines towards the th1 phenotype in several biological models. given the importance of dendritic cells (dcs) in the orchestration of imm ... | 2015 | 25978357 |
| bacteriology of pressure ulcers in individuals with spinal cord injury: what we know and what we should know. | individuals with spinal cord injury (sci) are at increased risk for the development of pressure ulcers. these chronic wounds are debilitating and contribute to prolonged hospitalization and worse medical outcome. however, the species of bacteria and the role that specific species may play in delaying the healing of chronic pressure ulcers in the sci population has not been well characterized. this study will review the literature regarding what is known currently about the bacteriology of pressu ... | 2015 | 25130374 |
| in vitro spectrum of pexiganan activity when tested against pathogens from diabetic foot infections and with selected resistance mechanisms. | pexiganan, a 22-amino-acid synthetic cationic peptide, is currently in phase 3 clinical trials as a topical antimicrobial agent for the treatment of mild infections associated with diabetic foot ulcers. bacterial isolates from the 2013 sentry antimicrobial surveillance program designated as pathogens from diabetic foot infections (dfi) and gram-negative and -positive pathogens from various infection types that harbored selected resistance mechanisms/phenotypes were tested against pexiganan in re ... | 2015 | 25583717 |
| chronic prostatitis: a possible cause of hematospermia. | while hematospermia is mainly caused by genitourinary inflammatory disorders, very few studies have been published on prostatitis-associated hematospermia (pah) diagnosed using robust prostatitis evaluation methods. therefore, we have evaluated the incidence of pah by using systematic methods for evaluating prostatitis. | 2015 | 26331127 |
| in vitro activity of azd0914, a novel bacterial dna gyrase/topoisomerase iv inhibitor, against clinically relevant gram-positive and fastidious gram-negative pathogens. | azd0914, a new spiropyrimidinetrione bacterial dna gyrase inhibitor with a novel mode of inhibition, has activity against bacterial species commonly cultured from patient infection specimens, including fluoroquinolone-resistant isolates. this study assessed the in vitro activity of azd0914 against key gram-positive and fastidious gram-negative clinical isolates collected globally in 2013. azd0914 demonstrated potent activity, with mic90s for azd0914 of 0.25 mg/liter against staphylococcus aureus ... | 2015 | 26195518 |
| antimicrobial and cytotoxic effects of phosphoric acid solution compared to other root canal irrigants. | phosphoric acid has been suggested as an irrigant due to its effectiveness in removing the smear layer. | 2015 | 26018307 |
| epidemiology and antibiotic susceptibility of aerococci in urinary cultures. | in this study, we present population-based data regarding the prevalence of aerococci in clinical urinary samples. during a 3-month period, all aerococcal isolates from urinary samples from 2 clinical microbiology laboratories were collected. we identified 64 aerococcus urinae isolates and 40 aerococcus sanguinicola isolates, which correlates with an incidence of 33 cases of aerococcal bacteriuria per 100,000 inhabitants per year. the median age was 83years for all patients with aerococcal bacte ... | 2015 | 25497460 |
| aerobic bacterial microbiota isolated from the cloaca of the european pond turtle (emys orbicularis) in poland. | we conducted a comparative analysis of the aerobic cloacal bacteria of european pond turtles (emys orbicularis) living in their natural environment and juvenile turtles reared under controlled conditions in a breeding center. we included 130 turtles in the study. the aerobic bacteria isolated from the cloaca of the juvenile turtles were less diverse and more prevalent than the bacteria isolated from free-living adults. we isolated 17 bacterial species from juvenile captive turtles, among which t ... | 2015 | 25380369 |
| antimicrobial activity of protamine against oral microorganisms. | protamine is an arginine-rich polycationic protein extracted from sperm cells of vertebrates including fishes such as salmon. the purpose of this study was to investigate the suppressive effects of protamine on the growth of oral pathogens for possible usage in dental materials. minimal inhibitory concentration (mic) and minimal bactericidal concentration (mbc) were determined by the microdilution method. twelve strains of oral viridans streptococci, actinomyces naeslundii, actinomyces odontolyt ... | 2015 | 26699859 |
| the impact of absorbed photons on antimicrobial photodynamic efficacy. | due to increasing resistance of pathogens toward standard antimicrobial procedures, alternative approaches that are capable of inactivating pathogens are necessary in support of regular modalities. in this instance, the photodynamic inactivation of bacteria (pib) may be a promising alternative. for clinical application of pib it is essential to ensure appropriate comparison of given photosensitizer (ps)-light source systems, which is complicated by distinct absorption and emission characteristic ... | 2015 | 26236292 |
| strains of enterococcus faecalis differ in their ability to coexist in biofilms with other root canal bacteria. | to investigate the relationship between protease production and the ability of enterococcus faecalis strains to coexist in biofilms with other bacteria commonly recovered from infected root canals. | 2015 | 26172346 |
| variability of cutaneous and nasal population levels between patients colonized and infected by multidrug-resistant bacteria in two brazilian intensive care units. | to compare cutaneous and nasal population levels between patients colonized and infected by multidrug-resistant organisms in two intensive care units. | 2015 | 26770762 |
| graphene oxide-silver nanocomposite as a promising biocidal agent against methicillin-resistant staphylococcus aureus. | methicillin-resistant staphylococcus aureus (mrsa) has been responsible for serious hospital infections worldwide. nanomaterials are an alternative to conventional antibiotic compounds, because bacteria are unlikely to develop microbial resistance against nanomaterials. in the past decade, graphene oxide (go) has emerged as a material that is often used to support and stabilize silver nanoparticles (agnps) for the preparation of novel antibacterial nanocomposites. in this work, we report the syn ... | 2015 | 26586946 |
| effect of treatment with an overheated dry-saturated steam vapour disinfection system on multidrug and extensively drug-resistant nosocomial pathogens and comparison with sodium hypochlorite activity. | the development of portable steam generators has made disinfection of the environment more practical. this study assessed the "in vitro" ability of an overheated dry-saturated steam vapour system to kill multidrug and extensively-drug resistant nosocomial pathogens, defining the antimicrobial spectrum and the contact times compared with the activity of sodium hypochlorite. | 2015 | 26452549 |
| selected compounds structurally related to acyclic sesquiterpenoids and their antibacterial and cytotoxic activity. | by implementing a common and industrially used method, 30 compounds which are structurally related to geranyl acetone, nerolidol, farnesal, farnesol and farnesyl acetate were obtained. their antimicrobial activity against staphylococcus aureus, enterococcus faecalis, enterococcus faecium, escherichia coli, klebsiella pneumoniae and acinetobacter baumannii bacteria was investigated. pharmacophore models were proposed based on the obtained results and 3d qsar modelling. cytotoxic effects against m ... | 2015 | 26096434 |
| [bloodstream infections in southwestern china: 2012 whire union report on bacterial susceptibility to antibiotics]. | to test the susceptibility of blood culture isolates to antibiotics in a sample of hospitals in southwestern china in 2012. | 2015 | 25993745 |
| tridentate hydrazone metal complexes derived from cephalexin and 2-hydrazinopyridine: synthesis, characterization and antibacterial activity. | metal(ii) coordination compounds of a tridentate hydrazone ligand (hl) derived from the condensation of cephalexin antibiotic with 2-hydrazinopyridine were synthesized. the hydrazone ligand and mononuclear [ml(oac)(h2o)] (m(ii)=mn, co, ni, cu, zn, ag) complexes were characterized by several techniques, including elemental and thermal analysis, molar conductance and magnetic susceptibility measurements, electronic, ft-ir, epr and (1)h nmr spectral studies. the cephalexin 2-pyridinylhydrazone liga ... | 2015 | 25677531 |
| drug resistance and molecular epidemiology of aerobic bacteria isolated from puerperal infections in bangladesh. | puerperal infection is a common complication during postnatal period in developing countries. bacterial species, drug resistance, and genetic characteristics were investigated for a total of 470 isolates from puerperal infections in bangladesh for a 2-year period (2010-2012). the most common species was escherichia coli (n=98), followed by enterococcus faecalis (n=54), staphylococcus haemolyticus (n=33), proteus mirabilis (n=32), staphylococcus aureus (n=27), klebsiella pneumoniae (n=22), and en ... | 2015 | 25555043 |
| first report of new delhi metallo-β-lactamase-1-producing strains in slovakia. | occurrence of carbapenemase-producing organisms, including new delhi metallo-β-lactamase-1 (ndm-1) is increasingly reported worldwide. the aim of this study was to assess the distribution of carbapenemase producers among multidrug-resistant gram-negative bacteria isolated from blood cultures. all carbapenem-resistant strains collected from december 2011 to december 2012 were analyzed. presence of carbapenemases was assessed with combined disc test and carba np test followed by polymerase chain r ... | 2015 | 25343711 |
| detection of airborne bacteria in a duck production facility with two different personal air sampling devices for an exposure assessment. | prevalent airborne microorganisms are not well characterized in industrial animal production buildings with respect to their quantity or quality. to investigate the work-related microbial exposure, personal bioaerosol sampling during the whole working day is recommended. therefore, bioaerosol sampling in a duck hatchery and a duck house with two personal air sampling devices, a filter-based pgp and a niosh particle size separator, was performed. subsequent, quantitative and qualitative analyses ... | 2015 | 25093856 |
| biological activities of xylooligosaccharides generated from garlic straw xylan by purified xylanase from bacillus mojavensis ueb-fk. | a newly isolated bacterium strain named ueb-fk was selected from tunisian sahara, exhibiting the highest clear zone on agar plates containing oat spelt xylan by staining with congo red. on the basis of 16s rdna sequence analysis, this strain was identified as bacillus mojavensis. this strain produced extracellular xylanase. xylanase from the strain was purified to homogeneity and had an apparent molecular weight of 14 kda. the k m and v max values of the purified xylanase on oat spelt xylan were ... | 2015 | 25351626 |
| study on in vivo effects of bacterial histidine kinase inhibitor, waldiomycin, in bacillus subtilis and staphylococcus aureus. | two-component signal transduction systems (tcss) represent one of the primary means by which bacteria sense and respond to changes in their environment, both intra- and extracellular. the highly conserved walk (histidine kinase)/walr (response regulator) tcs is essential for cell wall metabolism of low g+c gram-positive bacteria and acts as a master regulatory system in controlling and coordinating cell wall metabolism with cell division. waldiomycin, a walk inhibitor, has been discovered by scr ... | 2015 | 26582287 |
| antimicrobial and antioxidant properties of the crude peptide extracts of galatea paradoxa and patella rustica. | this study evaluated the antimicrobial and antioxidant activities of crude peptide extracted from galatea paradoxa (g. paradoxa) and patella rustica (p. rustica). the extracts were tested against eight strains of bacteria (escherichia coli, staphylococcus aureus, bacillus subtilis, salmonella typhi, enterococcus feacalis, klebseilla pneumoniae, streptococcus pneumoniae, pseudomonas aeruginosa) and one strain of fungi (candida albicans) using agar well diffusion and broth dilution assays. the ext ... | 2015 | 26405620 |
| graphene oxide-modified zno particles: synthesis, characterization, and antibacterial properties. | nanosized zno particles with diameters of 15 nm were prepared with a solution precipitation method at low cost and high yield. the synthesis of the particles was functionalized by the organic solvent dimethylformamide, and the particles were covalently bonded to the surface of graphene oxide. the morphology of the graphene oxide sheets and zno particles was confirmed with field emission scanning electron microscopy and biological atomic force microscopy. fourier transform infrared spectroscopy a ... | 2015 | 26347126 |
| antimicrobial action of sodium hypochlorite and castor oil solutions for denture cleaning - in vitro evaluation. | the objective of this in vitro study was to evaluate the antimicrobial action of sodium hypochlorite (0.25% and 0.50%) and 10% castor oil solutions against specific microorganisms, by counting colony forming units (cfu) of clinically important bacteria and candida species. acrylic resin specimens (n = 320; lucitone 550) were obtained from square metal matrices (10 x 10 x 2 mm), sterilized by microwave (650w, for 6 minutes) and contaminated by staphylococcus aureus, pseudomonas aeruginosa, candid ... | 2015 | 26313346 |
| synthesis, antibacterial and qsar evaluation of 5-oxo and 5-thio derivatives of 1,4-disubstituted tetrazoles. | a series of 1,4-disubstituted tetrazol-5-ones 3a, 5, 7, 12, 13 and 1,4-disubstituted tetrazol-5-thiones 3b, 9, 10 was synthesized and fully characterized by ir, ms, (1)h nmr and (13)c nmr. the series was evaluated for in vitro antibacterial activity against four gram negative (escherichia coli, proteus mirabilis, klebsiella pneumonia, and pseudomonas aeruginosa) and three gram positive (staphylococcus aureus, enterococcus faecalis, and bacillus subtilis) bacteria. the zone of inhibition was meas ... | 2015 | 26243367 |
| biological activities of morus celtidifolia leaf extracts. | the aims of this research were to examine the antibacterial, cytotoxic and antiradical/antioxidant activities of the organic extracts obtained from the leaves of the medicinal plant morus celtidifolia (family: moraceae). to evaluate its antimicrobial properties, m. celtidifolia was tested against the bacteria of medical importance: bacillus subtilis, staphyloccocus aureus, enterococcus faecalis, escherichia coli, enterobacter cloacae and enterobacter aerogenes. cytotoxic activity was assessed by ... | 2015 | 26142508 |
| antibacterial mode of action of the hydroethanolic extract of leonotis nepetifolia (l.) r. br. involves bacterial membrane perturbations. | leonotis nepetifolia (l) r. br., lamiaceae, a pantropical shrub, popularly known in brazil as "cordão-de-frade", "rubim", is reportedly used in brazilian ethnomedicine as well as in different countries in the treatments of ailments such as infections, inflammations, wounds, stomach disorders, among others. | 2015 | 26102550 |
| antibacterial and antiproliferative activities of plumericin, an iridoid isolated from momordica charantia vine. | plumericin, an iridoid lactone, was isolated with relatively high yield from momordica charantia vine using the supercritical fluid extraction (sfe) and the separation box (sepbox) comprising dual combination of high-performance liquid chromatography and solid phase extraction. this compound showed antibacterial activity against enterococcus faecalis and bacillus subtilis with minimum inhibitory concentration (mic) values better than cloxacillin. plumericin potently inhibited proliferation of tw ... | 2015 | 25945113 |