Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| a novel germline mutation of the pten gene in a patient with macrocephaly, ventricular dilatation, and features of vater association. | mutations of the pten gene are associated with hamartoma-neoplasia syndromes. while germline mutations at this chromosome 10q22-23 locus have been observed in patients with cowden syndrome (cs) and bannayan-riley-ruvalcaba syndrome (brr), both of which phenotypes are associated with hamartomata and neoplasia, somatic mutation of pten has been established in a wide variety of sporadically occurring neoplasia. cs and brr share some clinical features, specifically hamartomata and lipomatosis. inves ... | 2001 | 11748304 |
| minipodia and rosette contacts are adhesive organelles present in free-living amoebae. | using scanning electron microscopy, amoeba proteus cells migrating on the glass have been shown to develop dense coats of minipodia, which are discrete microprotrusions up to 8 microm long and approximately 0.5 microm across. they cover the middle-anterior area of the ventral cell surface, i.e. the region previously determined as the zone of most efficient adhesion of an amoeba to its substratum. minipodia are sparse underneath the frontal zone and lacking from the tail region. in amoebae that a ... | 2001 | 11748921 |
| catalytic and structural properties of irt-21 beta-lactamase (tem-77) from a co-amoxiclav-resistant proteus mirabilis isolate. | proteus mirabilis strain mag1, a clinical isolate that is resistant to broad-spectrum penicillins and co-amoxiclav, produces inhibitor-resistant tem (irt)-21, a novel mutant of tem beta-lactamase. this enzyme has a pi of 5.2 and is derived from the bla(tem-1a) gene ancestor. it contains two major amino acid substitutions specific for co-amoxiclav resistance (leu-69 for met and ser-244 for arg) that have never been found together previously. the dramatic loss of sensitivity to clavulanic acid, th ... | 2001 | 11750800 |
| pten mutations and proteus syndrome. | 2001 | 11755638 | |
| pten mutations and proteus syndrome. | 2001 | 11755639 | |
| cerebriform fibrous proliferation vs. proteus syndrome. | proteus syndrome is a rare, congenital hamartomatous syndrome that presents with a wide range of abnormalities. regardless of different manifestations found in different patients, there exists three mandatory criteria for the diagnosis of this syndrome: a mosaic distribution of the lesions, a progressive course, and sporadic occurrence. when these criteria are met, the presence of additional connective tissue nevi, which are encountered mostly on the plantar surface of the feet, suffices for the ... | 2001 | 11756840 |
| characterisation of p-nitrophenylglycerol-resistant proteus mirabilis super-swarming mutants. | p-nitrophenylglycerol (pnpg) inhibits the co-ordinately regulated activities of swarming behaviour and virulence factor expression in proteus mirabilis. the inhibitory action of pnpg was investigated by the isolation of tn5 insertion mutants that could swarm, albeit with much reduced ability, in the presence of pnpg. the mutants exhibited a super-swarming phenotype in the absence of pnpg; i.e., they migrated further in a given time than did the wild-type cells. cloning and sequence analysis of t ... | 2001 | 11761187 |
| synthesis and antimicrobial activity of new diazoimidazole derivatives containing an n-acylpyrrolidine ring. | a series of 4-diazoimidazole-5-carboxamides bearing in position 2 lipophilic substituents was synthesized and their antimicrobial activity was evaluated in vitro against pathogenic gram-positive, gram-negative bacteria and fungi. some compounds presented antifungal activity, particularly two derivatives (1g and 1h) showed good mic values (10-50 microg/ml) against both moulds and yeasts. | 2001 | 11765041 |
| bacterial agents of discharging ears and antimicrobial sensitivity patterns in children in ibadan, nigeria. | bacteriological studies were carried out on ear swabs from 361 cases of children with discharging ears at the microbiology department of the university college hospital, ibadan between march 1995 and february 1997. 308 (85.3%) had positive cultures. 78.6% of these yielded one isolate, 19.2% yielded two isolates while 2.2% had three isolates. pseudomonas spp. was the predominant agent of csom and asom. this was followed by staphylococcus aureus. other commonly isolated organisms were proteus and ... | 2001 | 11768012 |
| pyogenic thyroiditis and hiv infection. | infective thyroiditis remain rare disease entity. six patients were seen in jos, nigeria in the last five years. all of them were hiv positive. the presentation and management of these patients are high-lighted. the clinical features and bacteriology were similar to those previously documented for infective thyroiditis. | 2001 | 11768021 |
| normal oral bacterial flora from some southern african snakes. | eighteen snakes representing 11 species were subject to mouth swabbing on 58 occasions. of these swabs, 52.2% were positive for bacteria. a total of 92 bacterial isolates were cultured, representing 30 species of which 81.5% were enterobacteriaceae, 16.3% gram positive cocci, and 2.2% anaerobes. swabs from non-venomous snakes were more commonly bacteriologically sterile than those from venomous snakes (p = 0.0107). the oral bacterial flora did not differ between captive and newly captured snakes ... | 2001 | 11769348 |
| comparison of laterally condensed .06 and .02 tapered gutta-percha and sealer in vitro. | the purpose of this in vitro study was to compare the quality of the seal in canals prepared in a standardized manner and obturated with a .06 or a .02 tapered gutta-percha master cone using lateral condensation. forty-four extracted human anterior teeth with single, straight canals were divided into two experimental groups of 20 teeth each and two control groups of 2 teeth each. the teeth were instrumented with series 29 profile .06 tapered rotary nickel-titanium files to a master apical file o ... | 2001 | 11771592 |
| ertapenem: a new carbapenem. | ertapenem is a new 1-beta-methyl carbapenem, stable to dehydropeptidase, which binds preferable to penicillin-binding proteins (pbp) 2 and 3. ertapenem has a broad antibacterial spectrum with mic90 values < 0.5 mg/l for penicillin-susceptible streptococcus pneumoniae, streptococcus pyogenes, methicillin-sensitive staphylococcus aureus, haemophilus influenzae, moraxella catarrhalis, escherichia coli, citrobacter spp., klebsiella spp., serratia spp., proteus spp., clostridium perfringens, fusobact ... | 2001 | 11772242 |
| mystic program: summary of european data from 1997 to 2000. | the meropenem yearly susceptibility test information collection (mystic) program is a global study providing in-vitro surveillance data on microbial susceptibility in centers that prescribe meropenem. this paper summarizes data on the activity of meropenem and five comparator agents against 13,793 clinical isolates from 31 centers in 10 european countries, 1997-2000. meropenem and imipenem demonstrated broad-spectrum activity against the tested organisms, including beta-lactamase-producing strai ... | 2001 | 11777657 |
| [tests for studying invasive properties of selected proteus mirabilis strains]. | proteus mirabilis is an important pathogen of the urinary tract infections (uti). lipopolysaccharide (lps, endotoxin) is one of the pathogenic factors of pathogenicity of these bacteria. in this paper we described the invasion of l929 mouse fibroblasts by p. mirabilis strains, classified into the o10, o23, o30, o43 serogroups. the maximal invasiveness was observed between 4-6 hours of incubation of the tested cells with bacteria. the cytotoxic effect slightly increased with the incubation time, ... | 2001 | 11785185 |
| molecular properties and metabolic effect on blood cells produced by a new toxin of enterobacter cloacae. | a new toxin of enterobacter cloacae able to lyse erythrocytes and leukocytes was found. purification of the toxin was performed by salt precipitation, gel filtration, ion exchange and hplc in c8 column. sds-page electrophoresis showed more than one bank corresponding to the leukotoxin able to form polymers and aggregate like some pore-forming cytotoxins (rtx). in culture supernatant the toxin showed 1 hu/ml (hemolytic unit) and 1.5 lu/ml (leukotoxic unit); after purification it reached 15 hu/ml ... | 2001 | 11787862 |
| [infective lithiasis. treatment and complications]. | to establish the criteria for treatment of staghorn stones according to stone surface and distribution in cadaver kidneys. | 2001 | 11789372 |
| adhesion of thrombin-stimulated and unstimulated blood platelets to collagen in the presence of proteus mirabilis lipopolysaccharides. | adhesion of blood platelets to collagen may be involved in pathogenesis of septic shock after damage of endothelial cells by lps or inflammatory cytokines. therefore, analysis of platelet adhesion in the presence of endotoxin seems to be of great importance. we studied in vitro the effects of lpss (s1959, r110, r45) from proteus mirabilis (smooth and rough types differing significantly in their composition) on the adhesion of unstimulated and thrombin-stimulated platelets to collagen. the adhesi ... | 2001 | 11798396 |
| synthesis and antibacterial activity of 5-nitrofuryl and 3-methoxy-2-nitrophenyl derivatives of 6 beta-aminopenicillanic, 7 beta-aminocephalosporanic and 7 beta-aminodesacetoxy-cephalosporanic acids. | a number of 5-nitrofuryl and 3-methoxy-2-nitrophenyl derivatives of 6 beta-aminopenicillanic (6 beta-apa), 7 beta-aminocephalosporanic (7 beta-aca) and 7 beta-aminodesacetoxycephalosporanic (7 beta-adca) acids were synthesized by the method of mixed anhydrides or via schiff bases. the chemical structures of the new compounds were confirmed by ir-, 1h-nmr and mass spectral data, obtained by negative ion electrospray ionization. the in vitro testing results indicated that all penicillins and cepha ... | 2001 | 11799847 |
| galectin-3-mediated adherence of proteus mirabilis to madin-darby canine kidney cells. | proteus mirabilis is an important cause of urinary tract infections (utis) and can result in acute pyelonephritis. proteus mirabilis expresses several, morphologically distinct, fimbrial species, and previous studies have shown that the nonagglutinating fimbriae (naf) mediate bacterial adherence to a number of cell lines, including madin-darby canine kidney (mdck) cells. immunoblot overlay analysis of the plasma membrane fraction from mdck cells with purified naf revealed a 34-kda band, which ha ... | 2001 | 11800020 |
| influence of different natural physical fields on biological processes. | in space flight conditions gravity, magnetic, and electrical fields as well as ionizing radiation change both in size, and in direction. this causes disruptions in the conduct of some physical processes, chemical reactions, and metabolism in living organisms. in these conditions organisms of different phylogenetic level change their metabolic reactions undergo changes such as disturbances in ionic exchange both in lower and in higher plants, changes in cell morphology for example, gyrosity in pr ... | 2001 | 11803963 |
| sudden increase in pseudomonas aeruginosa nosocomial strains with broad host range transfer of antibiotic resistance. | we investigated transfer of antibiotic resistance from 51 multiply resistant strains of pseudomonas aeruginosa isolated from seriously ill patients in the frankfurt university clinics. nine isolates directly transferred resistance to three recipient strains used. ticarcillin and cephalothin resistance determinants were accepted from eight isolates, and in one case a kanamycin resistance determinant was transferred. the total spectrum of resistance transferred demonstrated that several donor stra ... | 2001 | 11806620 |
| synthesis and antimicrobial activity of some 1,2,4-triazole-3-mercaptoacetic acid derivatives. | ethyl 5-(2-furyl)-4-ethyl-1,2,4-triazole-3-mercaptoacetate (2), 5-(2-furyl)-4-ethyl-1,2,4-triazole-3-mercaptoacetic acid hydrazide (3) and a series of new n-alkylidene/arylidene-5-(2-furyl)-4-ethyl-1,2,4-triazole-3-mercaptoacetic acid hydrazides (4a-f) were synthesized and evaluated for in vitro antibacterial activity against staphylococcus aureus atcc 6538. staphylococcus epidermidis atcc 12228, klebsiella pneumoniae atcc 4352, pseudomonas aeruginosa atcc 1539, escherichia coli atcc 8739, shige ... | 2001 | 11829115 |
| synthesis and evaluation of antibacterial activity of some 2-[[alpha-(4-substituted benzoyloxy)-alpha-phenylacetyl or methylacetyl]amino]-5-(4-methoxyphenyl)- 1,3,4-oxadiazoles. | in this study, a new series of 1-[[alpha-(4-substitutedbenzoyloxy)-alpha-phenylacetyl or methylacetyl]amino]-5-(4-methoxyphenyl)-1,3,4-oxadiazoles were obtained by condensation of 2-[(alpha-chloro-alpha-phenylacetyl or alpha-bromopropionyl)amino]-5-(4-methoxyphenyl)1,3,4-oxadiazoles with sodium salts of 4-substituted benzoic acids. structures of the compounds were assigned on the basis of spectral data (uv, ir, 1h nmr, el ms) and elemental analyses. the antibacterial activities of the novel comp ... | 2001 | 11829119 |
| a new biologically active triterpenoid saponin from the leaves of lepidagathis hyalina nees. | a new biologically active triterpenoid saponin m.f. c42h68o13, m.p. 315 degrees-317 degrees c was isolated from the ethyl acetate soluble fraction of the methanolic extract of the leaves of lepidagathis hyalina. its structure was characterized as 3-beta-o-[alpha-l-rhamnopyranosyl(1-->4)o-beta-d-glucopyranosyl]16-alpha-hydroxy-olean-12-en(13)-28-oic acid by several spectral and chemical analysis. this new triterpenoid saponin showed antimicrobial activity against various plants pathogenic bacteri ... | 2001 | 11841115 |
| [etiological factors of urinary tract infections in children]. | etiological factors of urinary tract infection in children have been studied. the escherichia coli, klebsiella sp., enterococcus sp. and enterobacter sp. were the most often isolated bacteria from infant and baby urine. in this age group of patients uromycoses were also affirmed. from the urine of older children (1-18 years old) mainly escherichia coli, enterococcus sp., proteus sp. and morganella morganii have been raised. uropathogens' occurrence was analysed by a statistical method in the rel ... | 2001 | 11852813 |
| in vitro activity of moxifloxacin against local bacterial isolates. | the emergence of resistance to common antimicrobials in bacteria has been increasingly reported in various countries. empirical antimicrobial therapy of various infections would therefore need to be reviewed. the introduction of new fluoroquinolones has created an interest in the use of these as possible agents in the empirical treatment of respiratory tract infections. | 2001 | 11817288 |
| comparison of aztreonam against other antibiotics used in urinary tract infections. | urinary tract infection is a very common problem in adults as well as in children. there is always need for the right antibiotic to be chosen for treatment. | 2001 | 11873424 |
| [recurrent purulent bacterial meningoencephalitis]. | during the period of 25 years there were 55 patients treated in our institute because of recurrent purulent bacterial meningoencephalitis(rpbme). this group consisted of 42 males (76%) and 13 (24%) females, the prevalent number (53%) of patients being under 21 years of age. the diagnosis of rpbme was based on the commonly accepted criteria and confirmed by the laboratory results of csf examination. the cause of the recurrences was established considering the skull x-ray examination, ct and mri. ... | 2001 | 11921730 |
| penile prosthesis infections. | in this retrospective review we looked at infection rates and risk factors in penile prosthesis recipients. computer registry records of patients implanted with three-piece inflatable prostheses from april 1986 to march 1999 were reviewed. bacteriological culture report data were obtained from the medical records. there were 491 three-piece inflatable penile prosthesis recipients with follow-up ranging from 1 to 168 months (mean 83). all patients were implanted more than 1 y ago. there were 10 i ... | 2001 | 11918248 |
| clinical and bacteriological aspects on the use of oxytetracycline and flunixin in primiparous cows with induced retained placenta and post-partal endometritis. | retention of the fetal membranes and post-partal endometritis (rfm) are common problems in dairy cows. treatment often includes manual removal of the placenta in combination with antibiotic treatment. earlier studies have shown that cows with endometritis post-partum have a strong tendency to recover spontaneously. the present study focused on treatments of post-partal endometritis with the prostaglandin synthesis inhibitor, flunixin (f) either alone or combined with oxytetracycline (t). the stu ... | 2001 | 11885742 |
| antibiotic susceptibility of blood culture isolates of enterobacteriaceae. a norwegian multicenter study. | from may to november 1997 each of six major hospitals throughout norway collected 72 to 104 consecutive blood culture isolates of enterobacteriaceae, altogether 563 isolates. escherichia coli was the predominating organism (69%), followed by klebsiella spp. (15%), enterobacter spp. (6%), and proteus mirabilis (4%). the susceptibility of the isolates to ampicillin, cefuroxime, ceftazidime, imipenem, tobramycin, and ciprofloxacin was determined by the e-test. 37% and 7% of the isolates were resist ... | 2001 | 11890566 |
| assessment of the capacity of lactobacillus to inhibit the growth of uropathogens and block their adhesion to vaginal epithelial cells. | to gain insight into the mechanisms by which lactobacillus blocks the adherence of uropathogens to vaginal epithelial cells and inhibits their growth, 15 lactobacillus strains and 22 uropathogens were studied. lactobacilli from hemagglutination group iii, identified as lactobacillus crispatus, showed greater capacity to block uropathogen adherence than those from hemagglutination groups ii and i (61.9%, 49.5%, and 52.6% of blockage, respectively). pseudomonas aeruginosa pa5 and klebsiella pneumo ... | 2001 | 11133381 |
| behavioural, physiological and metabolic responses to long-term starvation and refeeding in a blind cave-dwelling (proteus anguinus) and a surface-dwelling (euproctus asper) salamander. | the effects of long-term starvation and subsequent refeeding on haematological variables, behaviour, rates of oxygen consumption and intermediary and energy metabolism were studied in morphologically similar surface- and cave-dwelling salamanders. to provide a hypothetical general model representing the responses of amphibians to food stress, a sequential energy strategy has been proposed, suggesting that four successive phases (termed stress, transition, adaptation and recovery) can be distingu ... | 2001 | 11136613 |
| conserved regulatory elements of the promoter sequence of the gene rpoh of enteric bacteria. | the rpoh regulatory region of different members of the enteric bacteria family was sequenced or downloaded from genbank and compared. in addition, the transcriptional start sites of rpoh of yersinia frederiksenii and proteus mirabilis, two distant members of this family, were determined. sequences similar to the sigma(70) promoters p1, p4 and p5, to the sigma(e) promoter p3 and to boxes dnaa1, dnaa2, camp receptor protein (crp) boxes crp1, crp2 and box cytr present in escherichia coli k12, were ... | 2001 | 11139607 |
| impact of fluoroquinolone administration on the emergence of fluoroquinolone-resistant gram-negative bacilli from gastrointestinal flora. | we assessed the risk factors for acquisition of fluoroquinolone-resistant, gram-negative organisms in the gastrointestinal tract of hospitalized patients. we analyzed stool samples from 204 patients and recovered fluoroquinolone-resistant, gram-negative organisms from 63. receipt of fluoroquinolone during the month preceding admission was the only risk factor identified, whereas female sex, duration of hospitalization, exposure to indwelling devices, admission from another hospital, and history ... | 2001 | 11112677 |
| properties of multidrug-resistant, esbl-producing proteus mirabilis isolates and possible role of beta-lactam/beta-lactamase inhibitor combinations. | at our institution, isolation rates of clinical strains of esbl-producing proteus mirabilis increased to 8.8% of all p. mirabilis isolates during the period 1997-1999. to evaluate the susceptibility of esbl-producing p. mirabilis strains against commonly used drugs, we studied 50 non-duplicated isolates selected on the basis of synergy between clavulanate and beta-lactams (ceftazidime, aztreonam, cefotaxime, and ceftriaxone). the presence of esbl-coding genes was confirmed by colony hybridizatio ... | 2001 | 11165117 |
| acute mastoiditis--the antibiotic era: a multicenter study. | to evaluate the clinical course and identify the causative organisms of acute mastoiditis in a community where most of the patients who develop acute otitis media are treated with antibiotics. | 2001 | 11165635 |
| urinary tract pathogens in complicated infection and in elderly individuals. | 2001 | 11171003 | |
| resistance patterns among nosocomial pathogens: trends over the past few years. | multiple surveillance studies have demonstrated that resistance among prevalent pathogens is increasing at an alarming rate, leading to greater patient morbidity and mortality from nosocomial infections. among gram-positive organisms, the most important resistant pathogens are methicillin- (oxacillin-)resistant staphylococcus aureus, beta-lactam-resistant and multidrug-resistant pneumococci, and vancomycin-resistant enterococci. important causes of gram-negative resistance include extended-spect ... | 2001 | 11171776 |
| in vitro and in vivo antimicrobial activity of topical ofloxacin and other ototopical agents. | ototopical agents are extensively used for otitis externa (oe), acute otitis media identified by otorrhea in patients who have tympanostomy tubes (aom-tt) and chronic suppurative otitis media (csom). the quinolones have particular value as ototopical agents because of the broad spectrum of antibacterial activity of importance in otic diseases and the high concentrations of antibacterial activity at the site of infection. | 2001 | 11176586 |
| hypertrophic toe in a 44-year-old man. | 2001 | 11176696 | |
| interaction of proteus mirabilis urease apoenzyme and accessory proteins identified with yeast two-hybrid technology. | proteus mirabilis, a gram-negative bacterium associated with complicated urinary tract infections, produces a metalloenzyme urease which hydrolyzes urea to ammonia and carbon dioxide. the apourease is comprised of three structural subunits, urea, ureb, and urec, assembled as a homotrimer of individual ureabc heterotrimers (ureabc)(3). to become catalytically active, apourease acquires divalent nickel ions through a poorly understood process involving four accessory proteins, ured, uree, uref, an ... | 2001 | 11157956 |
| flagellin, a novel mediator of salmonella-induced epithelial activation and systemic inflammation: i kappa b alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction. | gram-negative sepsis is mediated by the actions of proinflammatory genes induced in response to microbes and their products. we report that flagellin, the monomeric subunit of flagella, is a potent proinflammatory species released by salmonella. flagellin (1 microgram/ml) induces ikappabalpha degradation, nf-kappab nuclear translocation, and inducible no synthase expression in cultured intestinal epithelial cells (iec). aflagellic salmonella mutants do not induce nf-kappab activation or no produ ... | 2001 | 11145708 |
| catheter-associated urinary tract infections. | in the past few years it has been clearly demonstrated that the concept of bacterial biofilm production permits an understanding and provides some explanation of the pathogenesis, diagnosis and treatment of catheter-associated urinary tract infections. this concept describes the colonization of catheter surfaces and the movement of bacteria against the urinary flow. it explains the antibacterial resistance of these matrix-enclosed sessile populations of bacteria. the catheter encrustation can be ... | 2001 | 11148750 |
| immunocytochemical demonstration of visual pigments in the degenerate retinal and pineal photoreceptors of the blind cave salamander (proteus anguinus). | visual pigments in the regressed eye and pineal of the depigmented neotenic urodele, the blind cave salamander (proteus anguinus anguinus), were studied by immunocytochemistry with anti-opsin antibodies. the study included light- and electron-microscopic investigations of both the eye and the pineal organ. a comparison was made with the black pigmented subspecies proteus anguinus parkelj (black proteus), which has a normal eye structure. in the retina of the black proteus, we found principal rod ... | 2001 | 11236001 |
| bacterial protease ecp32 specifically hydrolyzing actin and its effect on cytoskeleton in vivo. | a procedure for isolation of bacterial protease ecp32 yielding 100 microg of the enzyme from 10 liters of the escherichia coli strain a2 liquid culture has been developed. the procedure includes chromatography, ultrafiltration, and page under non-denaturing conditions. the purified preparation contained about 80% ecp32 and did not exhibit atpase activity. polyclonal ecp32-specific antibodies have been produced, and a two-stage procedure for the isolation of protease ecp32 involving affinity chro ... | 2001 | 11240398 |
| lactobacillus plantarum reduces infection of pancreatic necrosis in experimental acute pancreatitis. | infection is the commonest cause of death in acute pancreatitis. early reduction of commensal flora (particularly lactobacillus species) and, at the same time, overgrowth of enterobacteriaceae, especially escherichia coli, have recently been described during acute pancreatitis. lactobacillus plantarum has been shown to be effective in reducing the egress of endotoxin and microbial translocation in several experimental models such as chemically induced hepatitis and ulcerative colitis. | 2001 | 11244259 |
| chronic osteomyelitis: clarification of nuclear medicine findings by fusion scans. | 2001 | 11245118 | |
| [efficacy of bacteriophages in complex treatment of patients with burn wounds]. | results of clinical and laboratory evaluation of the treatment with pyobacteriophage in tablets of the patients with burn wounds are presented. it was shown that phagotherapy provided more rapid cure of pyoseptic complications, temperature normalization, wounds purification and lower lethality bacteriological analysis of wound secretions revealed that after the treatment staphylococci and streptococci were cultured 2 times rarely, proteus spp. were isolated 1.5 times rarely, e. coli was not isol ... | 2001 | 11221078 |
| physiological and behavioral responses of stonefly nymphs to enhanced limestone treatment of acid mine drainage. | a new acid mine drainage (amd) treatment system uses pulsed, fluidized beds of limestone, and carbon dioxide pretreatment of influent amd, to enhance limestone neutralization of amd. we conducted laboratory studies to evaluate the behavior and physiology of larval stoneflies (pteronarcys proteus, plecoptera) exposed to effluents produced by the treatment system. survival, sodium balance, drift, and feeding responses by p. proteus to treated and untreated amd were examined. p. proteus nymphs exhi ... | 2001 | 11228958 |
| effect of subclinical uterine infection on cervical and uterine involution, estrous activity and fertility in postpartum buffaloes. | nili-ravi buffaloes (n=29) that calved normally between august and november and did not develop any clinical reproductive disorder after calving were studied for the incidence of sub-clinical bacterial infection of the uterus and its effects on postpartum reproductive efficiency. the incidence of subclinical uterine infection was 24% (7/29). involution of the cervix and uterus was slower (p < 0.01) in the infected group than in the normal group (45.6 vs 31.1 days and 46.3 vs 35.8 days), respecti ... | 2001 | 11233783 |
| [endonuclease from proteus mirabilis]. | two isoforms of nuclease displaying dnase and rnase activities were found in the culture liquid and periplasm of proteus mirabilis. the enzyme was isolated from the periplasm and then purified to a functionally homogeneous state. the nuclease was equally potent in cleaving denatured and native dnas by the endonuclease mechanism and was designated pm endonuclease. the endonuclease was shown to be a temperature-dependent enzyme with a ph optimum of 10.4-10.6, requiring the presence of bivalent met ... | 2001 | 11234403 |
| biogenic amines produced by enterobacteriaceae isolated from meat products. | biogenic amines in ground meat and processed meat products are one of the indicators to determine the poor quality raw material. major histamine forming bacterium was escherichia coli (strain ec04 with 65.88 mg/100 ml in brain heart infusion medium), followed by the microorganisms morganella morganii (strain mm4 with 8.40 mg/100 ml and strain mm7 with 8.28 mg/100 ml) and proteus mirabilis (strain pm02 with 8.76 mg/100 ml), respectively. the highest putrescine production level was found in citrob ... | 2001 | 22062111 |
| urease | urease is produced by numerous taxonomically diverse bacterial species, including normal flora and nonpathogens. also, urease has been demonstrated as a potent virulence factor for some species, including proteus mirabilis (51), staphylococcus saprophyticus (36), and helicobacter pylori (23). urease is central to h. pylori metabolism and virulence, is necessary for its colonization of the gastric mucosa, and is a potent immunogen that elicits a vigorous immune response. this enzyme is used for t ... | 2001 | 21290719 |
| effect of starter culture and storage temperature on the content of biogenic amines in dry fermented sausage polican. | water activity, ph, microbial counts (total counts/tcm/, coliforms, enterobacter, proteus, pseudomonas, escherichia and lactobacillus spp., respectively), and seven biogenic amines (ba) were determined in dry fermented sausage 'polican' produced using starter culture a (lactobacillus sakei, staphylococcus carnosus, s. xylosus) or b (l. sakei, s. carnosus, pediococcus pentosaceus), ripened 42 days, and subsequently stored at 8 or 22°c 60 days. counts of lactobacilli were higher and tcm lower in t ... | 2001 | 22062781 |
| susceptibility of community gram-negative urinary tract isolates to mecillinam and other oral agents. | to determine the susceptibility of community outpatient gram-negative urinary tract isolates to mecillinam and other commonly used oral agents. | 2001 | 18159352 |
| haemagglutination, haemolysin production and serum resistance of proteus and related species isolated from clinical sources. | a total of 148 strains of proteus and related species comprising of proteus mirabilis (116), proteus vulgaris (24), providentia rettgeri (4), providentia alcalifaciens (2), providentia stuarti (1) and morganella morganii (1), isolated from various sources, were examined for haemagglutination (ha), haemolysin production (hl) and serum resistance (sr). maximum isolates were obtained from urine (47.30%) and pus (40.54%) and they were multidrug resistant. the sensitivity to ciprofloxacin was 78.38%, ... | 2001 | 17664798 |
| in vitro susceptibility of nosocomial isolates against a new aminoglycoside isepamicin. | isepamicin is a new aminoglycoside with a spectrum of activity similar to amikacin with an advantage of possessing a high level of stability against different aminoglycoside modifying enzymes. the in vitro susceptibility of nosocomial isolates obtained from patients admitted to the all india institute of medical sciences, new delhi during october-december, 1999 was tested against isepamicin and compared with other aminoglycosides. | 2001 | 21910285 |
| directed evolution and phenomics screening of new biocatalysts. | biodiversity screening and directed evolution are two fruitful complementary approaches for the discovery and design of novel biocatalysts. a new technology for directed evolution, l-shuffling, has been designed and patented by proteus. l-shuffling technology offers several competitive advantages over other technologies including (i) directed evolution of large genes: l-shuffling" means "large-shuffling"; (ii) high fidelity recombination and (iii) control over location and frequency of recombina ... | 2001 | 15954596 |
| [bacterial causes of meningitis in newborns]. | bacterial meningitis jeopardizes the life of affected newborns and in survived children often leaves permanent sequels. the sooner the diagnosis is established and the therapy is started, the more a prosperous outcome can be expected. when the indication is established, lumbar punction should be performed. on the basis of the results of cytological and biochemical analyses of the cerebrospinal fluid (csf) that point to bacterial meningitis, the initial therapy should begin even before the result ... | 2001 | 15637989 |
| urinary calculi: bacteriological and chemical association. | we investigated the bacteriology of urinary calculi in relation to urinary tract infection, stone formation, chemical composition and antibiotic sensitivity. fifty-two patients (37 males, 15 females) with urolithiasis were studied. urine, serum and urinary calculi specimens were taken and serum biochemical tests to detect uric acid, calcium and phosphorus were performed. urine analysis and culture were also performed. of the 52 patients, 19 (37%) had associated urinary tract infection, with esch ... | 2001 | 15332777 |
| comparative in-vitro activities of commonly available quinolones and other antibiotics on bacterial isolates in ibadan, nigeria. | the 4-quinolones, many of which are now available in nigeria under different trade names, have a broad spectrum of activity. an evaluation is made of the comparative in-vitro activities of these quinolones and other antibiotics against 125 strains of bacteria commonly isolated from clinical specimens in university college hospital, ibadan, by using the stroke's disc sensitivity method, and mic estimation. the quinolones showed greater activity than the cephalosprins against klebsiella spp., prot ... | 2001 | 14510147 |
| antimicrobial resistance patterns among urine isolates from patients in a geriatric hospital and from older patients in a general hospital in jerusalem. | urinary tract infection is the most common cause of nosocomial infections in patients hospitalized in chronic care facilities. the changing spectrum of microorganisms involved in urinary tract infections and the emerging resistance require continuous monitoring to provide crucial information to guide empirical therapy and encourage prudent use of antibiotics. the aim of this survey was to assess the antimicrobial resistance profile of urine isolates from patients hospitalized in a geriatric hosp ... | 2001 | 12812604 |
| [cefepime (maxipime), large spectrum 4th generation cephalosporin, resistant to beta-lactamases]. | as a result of the appearance of bacterial strains resistant to 3rd generation cephlosporin, since 1993 cephalosporins of 4th generation have been developed and introduced in therapy; among them are: cefepime and cefpirome. cefepime is the most active 4th generation cephalosporin possessing the following advantages over the 3rd generation cephalosporins: high intrinsic potency due to rapid penetration into the periplasmic space; an extended spectrum of activity that includes many gram-positive a ... | 2001 | 12731231 |
| using vac to treat a vascular bypass site infection. | 2001 | 12964221 | |
| prevalence of asymptomatic bacteriuria among pregnant women in benin city, nigeria. | a semi-quantitative screening for asymptomatic bacteriuria was carried out in the first trimester of 500 consecutive pregnant women in benin city. the purpose was to provide baseline data and rational therapy for asymptomatic bacteriuria in pregnant women. of the 500 women screened, 433 clinical specimens showed significant bacteriuria, representing an incidence of 86.6%. of this number, 38 (7.4%) were of mixed bacterial colonies while 395 (91%) were of single bacterial colonies. staphylococcus ... | 2001 | 12521882 |
| [the clinical investigation of bacteriology of chronic suppurative otitis media]. | to understand bacteriology of chronic suppurative otitis media (csom) and drug sensitivity of isolated bacteria for better treatment of csom. | 2001 | 12541726 |
| revisiting proteus: do minor changes in lectin structure matter in biological activity? lessons from and potential biotechnological uses of the diocleinae subtribe lectins. | significant differences in function have been observed among lectins structurally similar to concanavalin a, but their high homology with this widely used lectin has kept them in obscurity. the observation of large differences in the potency of many of these diocleinae lectins as stimulators of interferon-g production by human peripheral blood mononuclear cells has lead to a major effort to unravel their chemical structure and biological activity. modeling studies of some of these lectins reveal ... | 2001 | 12370020 |
| activity of ocimum sanctum (the traditional indian medicinal plant) against the enteric pathogens. | aqueous & alcoholic extracts of o. sanctum were prepared. two concentrations of these extracts (30 mg & 60 mg) were tried against the enteric pathogens & candida albicans by agar diffusion method. wide zones of inhibition were observed at 60 mg concentration of extract. aqeous extract showed wider zone of inhibition when compared to alcoholic extract. aqueous extract showed wider zones of inhibition for klebisella, e. coil, proteus & staphylococcus aureus. alcoholic extract showed wider zone for ... | 2001 | 12026506 |
| multiple antimicrobial resistance in gram negative bacilli isolated from clinical specimens, jimma hospital, southwest ethiopia. | a total of 413 clinical specimens (pus, blood, urine, and stool) collected from patients admitted to jimma hospital were cultured for isolation and identification of aerobic bacteria and antimicrobial susceptibility testing. out of these, 124 specimens yielded one or more gram-negative bacilli strains. frequent gram negative bacterial isolates were proteus species 34(27%), klebsiella species 26(21%), enterobacter species 24(19%), and e. coli 24(19%). antimicrobial susceptibility test results sho ... | 2001 | 12380230 |
| enzyme fingerprints by fluorogenic and chromogenic substrate arrays we would like to thank prof. r. furstoss and dr. a. archelas at the faculté des sciences de luminy, marseille, france, for providing a sample of aspergillus niger eh, and dr. c. weijers at the department of food technology and nutrition sciences, wageningen university, the netherlands, for providing a sample of rhodotorula glutinis eh. this work was supported by the university of bern, the european cost program (action d12), the swiss office fédéral de l'education et de la science, protéus sa (nîmes, france), the ministero della università e della ricerca scientifica e tecnologica (murst), and consiglio nazionale delle ricerche (cnr) (roma). p.c. gratefully acknowledges merck for generous financial support from a 2000 adp chemistry award. | 2001 | 12404444 | |
| antimicrobial activity of dequalinium chloride against leading germs of vaginal infections. | dequalinium chloride (cas 522-51-0) and povidone iodine (cas 25655-41-8) are known as antiseptic agents and used in the local treatment of vaginal infections. clotrimazole (cas 23593-75-1) is an anti-fungal drug and applied primarily in the therapy of vulvo-vaginal candidiasis and to a lesser extent in bacterial vaginosis and trichomoniasis. however, antimicrobial activities of those three agents in comparison to each other have not been reported so far. to address this issue the antimicrobial a ... | 2002 | 12404886 |
| anti-salmonella activity of alkyl gallates. | a series of alkyl gallates (3,4,5-trihydroxybenzoates) was synthesized and tested for their antibacterial activity against salmonella choleraesuis. nonyl (c(9)) and octyl (c(8)) gallates were noted to be the most effective against this food-borne bacterium, each with a minimum bactericidal concentration (mbc) of 12.5 microg/ml, followed by decyl (c(10)) gallate, with a mbc of 25 microg/ml. dodecyl (c(12)) gallate exhibited activity against s. choleraesuis, with a mbc of 50 microg/ml. propyl (c(3 ... | 2002 | 12405763 |
| characterization of cmy-type beta-lactamases in clinical strains of proteus mirabilis and klebsiella pneumoniae isolated in four hospitals in the paris area. | we isolated five clinical strains (three proteus mirabilis and two klebsiella pneumoniae) with beta-lactam resistance phenotypes consistent with production of an ampc-type beta-lactamase. the predicted amino acid sequences of the enzymes were typical of class c beta-lactamases. the enzymes were identified as cmy-2, cmy-4 and a new cmy-variant beta-lactamase, cmy-12. the ampc beta-lactamases from the two k. pneumoniae isolates were found to be encoded on self-transferable plasmids. the genes enco ... | 2002 | 12407124 |
| modification of dienes mutual inhibition test for epidemiological characterization of pseudomonas aeruginosa isolates. | pseudomonas aeruginosa is an important cause of community-associated and nosocomial infections related to exposure to aqueous environments. such infections often occur in the setting of a common-source outbreak, in which case epidemiological characterization of isolates may be necessary. in this preliminary study, a modification of the dienes mutual inhibition test, ordinarily used to assess the relatedness of swarming proteus mirabilis strains, was used to study 15 p. aeruginosa isolates, with ... | 2002 | 12409411 |
| [fibrin-collagen substance as a vehicle for local application of antibacterial agents]. | inhibitory activity of fibrin-collagen substance (fcs) impregnated by various antibacterial agents against various microorganisms was investigated. it was demonstrated that antibacterials bind well with fcs, providing its sufficient antibacterial activity. determination of growth-inhibition zones showed that antibacterial agents diffuse into medium well and demonstrated the same activity as discs with antibiotics. for clinical practice it is recommended to use for impregnation the following drug ... | 2002 | 12422648 |
| antimicrobial properties and phytochemical constituents of the leaves of african mistletoe (tapinanthus dodoneifolius (dc) danser) (loranthaceae): an ethnomedicinal plant of hausaland, northern nigeria. | african mistletoe (tapinanthus dodoneifolius (dc) danser) called 'kauchi' in hausa is a hemi-plant parasite used ethnomedicinally by the hausa and the fulani tribes of northern nigeria as a remedy for several human and animal ailments that include stomach ache, diarrhoea, dysentery, wound and cancer. screening of the plant, obtained from 14 different hosts, revealed a wide spectrum of antimicrobial activities against certain multiple drug resistant bacterial and fungal isolates of farm animals. ... | 2002 | 12426091 |
| indigoferabietone, a novel abietane diterpenoid from indigofera longeracemosa with potential antituberculous and antibacterial activity. | from the stems of indigofera longeracemosa, a novel abietane diterpenoid, indigoferabietone was isolated. the structure was established by spectral techniques. the inhibitory activity of indigoferabietone (1) tested against mycobacterium tuberculosis and candida albicans, and the antibacterial activity tested against staphylococcus aureus, proteus vulgaris, and escherichia coli were found to be significant. | 2002 | 12426956 |
| the inner-core lipopolysaccharide biosynthetic waae gene: function and genetic distribution among some enterobacteriaceae. | to determine the function of the waae gene in the biosynthesis of the inner-core lps of klebsiella pneumoniae, a waae non-polar mutant has been constructed. data obtained from the comparative chemical analysis of lps samples obtained from the wild-type, the mutant strain and the complemented mutant demonstrated that the waae gene is involved in substitution of alpha-l-glycero-d-manno-heptopyranose i (l,d-heppi) at the o-4 position by a beta-d-glucopyranose (beta-d-glcp) residue. in addition, dna ... | 2002 | 12427940 |
| effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. | resveratrol (3, 4', 5-trihydroxystilbene), a natural polyphenol, is found in some plants that are used in human nutrition. grapes are a major source for resveratrol, and a significant amount can also be found in red wine. several experimental studies have demonstrated biological properties of resveratrol, especially its anti-inflammatory, antioxidant, anti-platelet and antitumor effects. in the present study, we investigated the first step of platelet activation-platelet adhesion stimulated by l ... | 2002 | 12431480 |
| lower genital tract infections in diabetic women. | the influence of glucose metabolism is seen in many infectious diseases, making diabetic patients more vulnerable to sepsis and other serious sequelae of bacterial invasion. vaginal candidiasis is a common problem if the glycemia is poorly controlled. the level of glucose concentration in the blood after ingestion of sugar seems to explain an increased likelihood of recurrent infection. specific immune aberrations, such as an elevated t-helper 2 response and a blunted t-helper 1 response, leadin ... | 2002 | 12433331 |
| distribution of extended-spectrum beta-lactamases in clinical isolates of enterobacteriaceae in vietnam. | among 730 escherichia coli, 438 klebsiella pneumoniae, and 141 proteus mirabilis isolates obtained between september 2000 and september 2001 in seven hospitals in ho chi minh city, vietnam, 26.6% were resistant to ceftazidime, 30% were resistant to cefotaxime, 31.5% were resistant to ceftriaxone, 15.9% were resistant to cefoperazone, and 6% were resistant to cefepime. resistance to imipenem was found in 5.6% of the isolates. in 55 strains producing extended-spectrum beta-lactamases (32 e. coli i ... | 2002 | 12435670 |
| biochemical characterization of tem-92 extended-spectrum beta-lactamase, a protein differing from tem-52 in the signal peptide. | a bla(tem-92) gene was cloned from a proteus mirabilis isolate and expressed in escherichia coli. production of the enzyme caused reduction of susceptibility to penicillins and narrow- to expanded-spectrum cephalosporins but not to moxalactam and cephamycins. determination of kinetic parameters with the purified enzyme revealed hydrolysis of expanded-spectrum cephalosporins, while cephamycins, moxalactam, and aztreonam were very poorly or not hydrolyzed. clavulanate and penicillanic acid sulfone ... | 2002 | 12435705 |
| pathological and therapeutic significance of cellular invasion by proteus mirabilis in an enterocystoplasty infection stone model. | proteus mirabilis infection often leads to stone formation. we evaluated how bacterium-mucin adhesion, invasion, and intracellular crystal formation are related to antibiotic sensitivity and may cause frequent stone formation in enterocystoplasties. five intestinal (caco-2, ht29, ht29-18n2, ht29-fu, and ht29-mtx) and one ureter cell line (sv-huc-1) were incubated in artificial urine with five proteus mirabilis strains. fluorescence-activated cell sorting (facs), laser scanning microscopy, and el ... | 2002 | 12438382 |
| a muscular lesion suggestive of focal myositis in a child with proteus syndrome. | proteus syndrome is a polymorphic hamartomatous disorder associated with a broad spectrum of rare congenital malformations. many neoplasms have been linked to this condition, including lipomas, lymphangiomas, and hemangiomas. the authors describe a case of a congenital muscular lesion in a child with proteus syndrome. this mass was painless but was growing out of proportion to her leg musculature. a magnetic resonance imaging scan and incisional biopsy showed findings consistent with focal myosi ... | 2002 | 12439276 |
| isolation of lacz fusions to proteus mirabilis genes regulated by intercellular signaling: potential role for the sugar phosphotransferase (pts) system in regulation. | using a mini-tn5lacz1 reporter transposon, lacz fusions have been identified in proteus mirabilis that are activated by the accumulation of self-produced extracellular signals. genes identified by this approach include putative homologs of pgm, nlpa and two genes of unknown function. the extracellular signal(s) involved in activation were resistant to the effects of acid and alkali. the signal required for activation of (nlpa) cma482::lacz was sensitive to protease, suggesting the signal is a pe ... | 2002 | 12445644 |
| brain abscess caused by aerobic gram-negative bacilli: clinical features and therapeutic outcomes. | thirty-three patients (24 males and nine females) with brain abscesses resulting from infection by aerobic gram-negative bacilli were identified at kaohsiung chang gung memorial hospital over a period of 14 years. of these, 23 cases developed spontaneously, with the remaining ten postneurosurgery. the organisms most frequently involved were klebsiella (k.) pneumoniae, pseudomonas aeruginosa, escherichia coli and proteus species and included some rare pathogens, such as salmonella and enterobacte ... | 2002 | 12445926 |
| brain abscess complicating cerebral infarct. | we report a case of a 68-year-old man who suffered ischemic strokes in the left middle cerebral artery territory and three months later, following urosepsis, developed a cerebral abscess in the infarcted area. | 2002 | 12446296 |
| the helicobacter pylori flba flagellar biosynthesis and regulatory gene is required for motility and virulence and modulates urease of h. pylori and proteus mirabilis. | helicobacter pylori and proteus mirabilis ureases are nickel-requiring metallo-enzymes that hydrolyse urea to nh3 and co2. in both h. pylori and in an escherichia coli model of h. pylori urease activity, a high affinity nickel transporter, nixa, is required for optimal urease activity, whereas the urea-dependent urer positive transcriptional activator governs optimal urease expression in p. mirabilis. the h. pylori flba gene is a flagellar biosynthesis and regulatory gene that modulates urease a ... | 2002 | 12448680 |
| structural and serological characterization of the lipopolysaccharide from proteus penneri 20 and classification of the cross-reacting proteus penneri strains 10, 16, 18, 20, 32 and 45 in proteus serogroup o17. | o-specific polysaccharide (o-antigen) of the lipopolysaccharide of proteus penneri 20 was studied using sugar analysis along with various one- and two-dimensional nmr spectroscopy techniques. the following structure of the polysaccharide was established: [formula: see text] it has the same carbohydrate backbone structure as that described earlier for p. penneri 16, in which the positions of the o-acetyl groups have not been determined. p. penneri 20 o-antiserum showed a strong cross-reactivity w ... | 2002 | 12455869 |
| identification of a chromosome-borne expanded-spectrum class a beta-lactamase from erwinia persicina. | from whole-cell dna of an enterobacterial erwinia persicina reference strain that displayed a penicillinase-related antibiotic-resistant phenotype, a beta-lactamase gene was cloned and expressed in escherichia coli. it encoded a clavulanic-acid-inhibited ambler class a beta-lactamase, erp-1, with a pi value of 8.1 and a relative molecular mass of ca. 28 kda. erp-1 shared 45 to 50% amino acid identity with the most closely related enzymes, the chromosomally encoded enzymes from citrobacter koseri ... | 2002 | 12384342 |
| is there a need for postoperative surveillance after day case groin surgery in children? | there is increasing awareness of the value of day case paediatric surgery in fulfilling the needs of the community. is this cost effective, are there hidden complications and is there a need for routine follow-up? seven hundred and thirty-one children attending the red cross war memorial children's hospital day surgery unit over a 32-month period, and undergoing 912 procedures confined to the inguinoscrotal region, were enrolled in the study. surgical procedures performed included inguinal herni ... | 2002 | 12387217 |
| comparison of three chromogenic agar plates for isolation and identification of urinary tract pathogens. | to comparatively assess the performance of three chromogenic agar plates, cps id2, chromogenic uti, and usa, for the detection and enumeration of all urinary tract pathogens and the direct identification of escherichia coli, proteus mirabilis and enterococcus spp. | 2002 | 12390282 |
| [psoas abscess. etiology and treatment]. | psoas abscess is in general a syndrome with low incidence. in the following, two cases are presented which describe the etiology, diagnosis, and treatment of primary and secondary retroperitoneal manifestations. the article mainly focuses on the different respective surgical procedures. because of its rareness, an overview of further cases discussed in the literature is provided. | 2002 | 12395166 |
| characterisation of local isolates of enterobacteriaceae from turkey. | 20 local isolates of enterics belonging to the genera salmonella, enterobacter, proteus, citrobacter from human, chicken and/or egg were characterised for their antibiotic resistance patterns, plasmid profiles, phage types, outer membrane proteins, and lipopolysaccharide patterns. relatedness of these characteristics for epidemiological analysis was assessed. 18 (90%) strains were resistant to at least one antibiotic and those (multi-drug resistant ones) resisting to two or more antibiotics cons ... | 2002 | 12398294 |
| infestation of fish-culturing communities with fish-borne bacteria: the ghanaian case. | twenty different bacterial species were isolated from fishermen and members of communities associated with seven fish ponds with different fertilizer treatments, and an open system. the number and types of the bacterial species were different for the different ponds. generally, neither the geographical location of the ponds nor the type of fertilizer used could be related to the bacterial flora. escherichia coli was the predominant species in all the communities, while escherichia coli, klebsiel ... | 2002 | 12400540 |
| serum levels of prophylactic cefazolin during cardiopulmonary bypass surgery. | controversy exists regarding the appropriate prophylactic dose of cefazolin for coronary artery bypass grafting (cabg) surgery requiring cardiopulmonary bypass (cpb) because the effect of cpb on serum drug levels is poorly understood. current standards of prophylaxis are based primarily on empiric studies. few studies have attempted to quantify serum cefazolin levels in either cardiac or noncardiac surgeries. this study was conducted to measure and assess the adequacy of the intraoperative serum ... | 2002 | 12400766 |
| [triclosan, a topical dermatologic agent. in vitro- and in vivo studies on the effectiveness of a new preparation in the new german formulary]. | triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether) is an antiseptic suitable for formulation as a w/o emulsion. the objective of the present study was to explore its potential utility in atopic dermatitis and prophylactic skin care following leg eczema and leg ulcer treatment. | 2002 | 12402134 |
| tryptophan indole-lyase from proteus vulgaris: kinetic and spectral properties. | an efficient method for purification of recombinant tryptophanase from proteus vulgaris was developed. catalytic properties of the enzyme in reactions with l-tryptophan and some other substrates as well as competitive inhibition by various amino acids in the reaction with s-o-nitrophenyl-l-cysteine were studied. absorption and circular dichroism spectra of holotryptophanase and its complexes with characteristic inhibitors modeling the structure of the principal reaction intermediates were examin ... | 2002 | 12460117 |