Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| horizontal transfer of β-carbonic anhydrase genes from prokaryotes to protozoans, insects, and nematodes. | horizontal gene transfer (hgt) is a movement of genetic information occurring outside of normal mating activities. it is especially common between prokaryotic endosymbionts and their protozoan, insect, and nematode hosts. although beta carbonic anhydrase (β-ca) plays a crucial role in metabolic functions of many living organisms, the origin of β-ca genes in eukaryotic species remains unclear. | 2016 | 26983858 |
| evidence for the induction of key components of the notch signaling pathway via deltamethrin and azamethiphos treatment in the sea louse caligus rogercresseyi. | the extensive use of organophosphates and pyrethroids in the aquaculture industry has negatively impacted parasite sensitivity to the delousing effects of these antiparasitics, especially among sea lice species. the notch signaling pathway is a positive regulator of abc transporter subfamily c expression and plays a key role in the generation and modulation of pesticide resistance. however, little is known about the molecular mechanisms behind pesticide resistance, partly due to the lack of geno ... | 2016 | 27187362 |
| wolbachia blocks viral genome replication early in infection without a transcriptional response by the endosymbiont or host small rna pathways. | the intracellular endosymbiotic bacterium wolbachia can protect insects against viral infection, and is being introduced into mosquito populations in the wild to block the transmission of arboviruses that infect humans and are a major public health concern. to investigate the mechanisms underlying this antiviral protection, we have developed a new model system combining wolbachia-infected drosophila melanogaster cell culture with the model mosquito-borne semliki forest virus (sfv; togaviridae, a ... | 2016 | 27089431 |
| zika virus strains potentially display different infectious profiles in human neural cells. | the recent zika virus (zikv) epidemic has highlighted the poor knowledge on its physiopathology. recent studies showed that zikv of the asian lineage, responsible for this international outbreak, causes neuropathology in vitro and in vivo. however, two african lineages exist and the virus is currently found circulating in africa. the original african strain was also suggested to be neurovirulent but its laboratory usage has been criticized due to its multiple passages. in this study, we compared ... | 2016 | 27688094 |
| pirna pathway is not required for antiviral defense in drosophila melanogaster. | since its discovery, rna interference has been identified as involved in many different cellular processes, and as a natural antiviral response in plants, nematodes, and insects. in insects, the small interfering rna (sirna) pathway is the major antiviral response. in recent years, the piwi-interacting rna (pirna) pathway also has been implicated in antiviral defense in mosquitoes infected with arboviruses. using drosophila melanogaster and an array of viruses that infect the fruit fly acutely o ... | 2016 | 27357659 |
| yellow fever virus capsid protein is a potent suppressor of rna silencing that binds double-stranded rna. | mosquito-borne flaviviruses, including yellow fever virus (yfv), zika virus (zikv), and west nile virus (wnv), profoundly affect human health. the successful transmission of these viruses to a human host depends on the pathogen's ability to overcome a potentially sterilizing immune response in the vector mosquito. similar to other invertebrate animals and plants, the mosquito's rna silencing pathway comprises its primary antiviral defense. although a diverse range of plant and insect viruses has ... | 2016 | 27849599 |
| genome investigations of vector competence in aedes aegypti to inform novel arbovirus disease control approaches. | dengue (denv), yellow fever, chikungunya, and zika virus transmission to humans by a mosquito host is confounded by both intrinsic and extrinsic variables. besides virulence factors of the individual arboviruses, likelihood of virus transmission is subject to variability in the genome of the primary mosquito vector, aedes aegypti. the "vectorial capacity" of a. aegypti varies depending upon its density, biting rate, and survival rate, as well as its intrinsic ability to acquire, host and transmi ... | 2016 | 27809220 |
| climate change influences on the global potential distribution of the mosquito culex quinquefasciatus, vector of west nile virus and lymphatic filariasis. | rapid emergence of most vector-borne diseases (vbds) may be associated with range expansion of vector populations. culex quinquefasciatus say 1823 is a potential vector of west nile virus, saint louis encephalitis virus, and lymphatic filariasis. we estimated the potential distribution of cx. quinquefasciatus under both current and future climate conditions. the present potential distribution of cx. quinquefasciatus showed high suitability across low-latitude parts of the world, reflecting the c ... | 2016 | 27695107 |
| morphological abnormalities and cell death in the asian citrus psyllid (diaphorina citri) midgut associated with candidatus liberibacter asiaticus. | candidatus liberibacter asiaticus (clas) is a phloem-limited, gram-negative, fastidious bacterium that is associated with the development of citrus greening disease, also known as huanglongbing (hlb). clas is transmitted by the asian citrus psyllid (acp) diaphorina citri, in a circulative manner. two major barriers to transmission within the insect are the midgut and the salivary glands. we performed a thorough microscopic analysis within the insect midgut following exposure to clas-infected cit ... | 2016 | 27630042 |
| the strica homolog aacasps16 is involved in apoptosis in the yellow fever vector, aedes albopictus. | caspases are a family of cysteine proteases playing essential roles during apoptosis. seven caspases identified in drosophila were dronc, dredd, strica, dcp-1, decay, drice and damm. among them, strica is an insect-specific caspase containing a long serine- and threonine- rich prodomain, of which function is not yet well studied. here we identified a homolog of strica from aedes albopictus, named as aacasps16. aacasps16 encoded a protein containing a putative serine- and threonine-rich prodomain ... | 2016 | 27351972 |
| mosquito saliva increases endothelial permeability in the skin, immune cell migration, and dengue pathogenesis during antibody-dependent enhancement. | dengue remains the most prevalent arthropod-borne viral disease in humans. while probing for blood vessels, aedes aegypti and ae. albopictus mosquitoes transmit the four serotypes of dengue virus (denv1-4) by injecting virus-containing saliva into the skin. even though arthropod saliva is known to facilitate transmission and modulate host responses to other pathogens, the full impact of mosquito saliva on dengue pathogenesis is still not well understood. inoculating mice lacking the interferon-α ... | 2016 | 27310141 |
| a glance at subgenomic flavivirus rnas and micrornas in flavivirus infections. | the family flaviviridae comprises a wide variety of viruses that are distributed worldwide, some of which are associated with high rates of morbidity and mortality. there are neither vaccines nor antivirals for most flavivirus infections, reinforcing the importance of research on different aspects of the viral life cycle. during infection, cytoplasmic accumulation of rna fragments mainly originating from the 3' utrs, which have been designated subgenomic flavivirus rnas (sfrnas), has been detect ... | 2016 | 27233361 |
| infection pattern and transmission potential of chikungunya virus in two new world laboratory-adapted aedes aegypti strains. | chikungunya virus (chikv) is an emerging mosquito-borne virus belonging to the togaviridae, which is transmitted to humans by aedes aegypti and ae. albopictus. we describe the infection pattern of chikv in two new world ae. aegypti strains, hwe and orl. both mosquito strains were susceptible to the virus but showed different infection patterns in midguts and salivary glands. even though acquisition of a bloodmeal showed moderate levels of apoptosis in midgut tissue, there was no obvious addition ... | 2016 | 27102548 |
| endogenously-expressed nh2-terminus of circumsporozoite protein interferes with sporozoite invasion of mosquito salivary glands. | the circumsporozoite protein is the most abundant polypeptide expressed by sporozoites, the malaria parasite stage capable of infecting humans. sporozoite invasion of mosquito salivary glands prior to transmission is likely mediated by a receptor/ligand-like interaction of the parasites with the target tissues, and the amino (nh2)-terminal portion of csp is involved in this interaction but not the tsr region on the carboxyl (c)-terminus. peptides based on the nh2-terminal domain could compete wi ... | 2016 | 26964736 |
| genomic approaches for understanding dengue: insights from the virus, vector, and host. | the incidence and geographic range of dengue have increased dramatically in recent decades. climate change, rapid urbanization and increased global travel have facilitated the spread of both efficient mosquito vectors and the four dengue virus serotypes between population centers. at the same time, significant advances in genomics approaches have provided insights into host-pathogen interactions, immunogenetics, and viral evolution in both humans and mosquitoes. here, we review these advances an ... | 2016 | 26931545 |
| small rna profiling in dengue virus 2-infected aedes mosquito cells reveals viral pirnas and novel host mirnas. | in aedes mosquitoes, infections with arthropod-borne viruses (arboviruses) trigger or modulate the expression of various classes of viral and host-derived small rnas, including small interfering rnas (sirnas), piwi interacting rnas (pirnas), and micrornas (mirnas). viral sirnas are at the core of the antiviral rna interference machinery, one of the key pathways that limit virus replication in invertebrates. besides sirnas, aedes mosquitoes and cells derived from these insects produce arbovirus-d ... | 2016 | 26914027 |
| transstadial effects of bti on traits of aedes aegypti and infection with dengue virus. | most mosquito control efforts are primarily focused on reducing the adult population size mediated by reductions in the larval population, which should lower risk of disease transmission. although the aim of larviciding is to reduce larval abundance and thus recruitment of adults, nonlethal effects on adults are possible, including transstadial effects on phenotypes of adults such as survival and pathogen infection and transmission. in addition, the mortality induced by control efforts may act i ... | 2016 | 26871951 |
| inhibition of chikungunya virus replication by 1-[(2-methylbenzimidazol-1-yl) methyl]-2-oxo-indolin-3-ylidene] amino] thiourea(mbzm-n-ibt). | chikungunya virus (chikv) infection is one of the most challenging human arboviral infections with global significance and without any specific antiviral. in this investigation, 1-[(2-methylbenzimidazol-1-yl) methyl]-2-oxo-indolin-3-ylidene] amino] thiourea (mbzm-n-ibt) was synthesised as a molecular hybrid of 2-methyl benzimidazole and isatin-β-thiosemicarbazone and its anti-chikv property was evaluated. the release of infectious virus particles was calculated by plaque assay, expression profil ... | 2016 | 26843462 |
| apoptosis, autophagy and unfolded protein response pathways in arbovirus replication and pathogenesis. | arboviruses are pathogens that widely affect the health of people in different communities around the world. recently, a few successful approaches toward production of effective vaccines against some of these pathogens have been developed, but treatment and prevention of the resulting diseases remain a major health and research concern. the arbovirus infection and replication processes are complex, and many factors are involved in their regulation. apoptosis, autophagy and the unfolded protein r ... | 2016 | 26781343 |
| viral metagenomics on blood-feeding arthropods as a tool for human disease surveillance. | surveillance and monitoring of viral pathogens circulating in humans and wildlife, together with the identification of emerging infectious diseases (eids), are critical for the prediction of future disease outbreaks and epidemics at an early stage. it is advisable to sample a broad range of vertebrates and invertebrates at different temporospatial levels on a regular basis to detect possible candidate viruses at their natural source. however, virus surveillance systems can be expensive, costly i ... | 2016 | 27775568 |
| an updated checklist of mosquito species (diptera: culicidae) from madagascar. | an updated checklist of 235 mosquito species from madagascar is presented. the number of species has increased considerably compared to previous checklists, particularly the last published in 2003 (178 species). this annotated checklist provides concise information on endemism, taxonomic position, developmental stages, larval habitats, distribution, behavior, and vector-borne diseases potentially transmitted. the 235 species belong to 14 genera: aedeomyia (3 species), aedes (35 species), anophel ... | 2016 | 27101839 |
| the insect-specific palm creek virus modulates west nile virus infection in and transmission by australian mosquitoes. | insect-specific viruses do not replicate in vertebrate cells, but persist in mosquito populations and are highly prevalent in nature. these viruses may naturally regulate the transmission of pathogenic vertebrate-infecting arboviruses in co-infected mosquitoes. following the isolation of the first australian insect-specific flavivirus (isf), palm creek virus (pcv), we investigated routes of infection and transmission of this virus in key australian arbovirus vectors and its impact on replication ... | 2016 | 27457250 |
| development and validation of a quantitative, one-step, multiplex, real-time reverse transcriptase pcr assay for detection of dengue and chikungunya viruses. | dengue virus (denv) and chikungunya virus (chikv) are important human pathogens with common transmission vectors and similar clinical presentations. patient care may be impacted by the misdiagnosis of denv and chikv in areas where both viruses cocirculate. in this study, we have developed and validated a one-step multiplex reverse transcriptase pcr (rt-pcr) to simultaneously detect, quantify, and differentiate between four denv serotypes (pan-denv) and chikungunya virus. the assay uses taqman te ... | 2016 | 27098955 |
| vector competence of aedes aegypti and aedes polynesiensis populations from french polynesia for chikungunya virus. | from october 2014 to march 2015, french polynesia experienced for the first time a chikungunya outbreak. two aedes mosquitoes may have contributed to chikungunya virus (chikv) transmission in french polynesia: the worldwide distributed ae. aegypti and the polynesian islands-endemic ae. polynesiensis mosquito. | 2016 | 27144888 |
| vertical transmission of indian ocean lineage of chikungunya virus in aedes aegypti and aedes albopictus mosquitoes. | the re-emergence of chikungunya (chik) fever in thailand has been caused by a novel lineage of chikungunya virus (chikv) termed the indian ocean lineage (iol). the aedes albopictus mosquito is thought to be a primary vector of chik fever in thailand, whereas ae. aegypti acts as a secondary vector of the virus. the vertical transmission is believed to be a primary means to maintain chikv in nature and may be associated with an increased risk of outbreak. therefore, the goal of this study was to a ... | 2016 | 27108077 |
| membrane feeding of dengue patient's blood as a substitute for direct skin feeding in studying aedes-dengue virus interaction. | understanding the interaction between aedes vectors and dengue viruses (denv) has significant implications in determining the transmission dynamics of dengue. the absence of an animal model and ethical concerns regarding direct feeding of mosquitoes on patients has resulted in most infection studies using blood meals spiked with laboratory-cultured denv. data obtained from such studies may not reflect the natural human-mosquito transmission scenario. this study explored the potential of using me ... | 2016 | 27083158 |
| rapid detection strategies for the global threat of zika virus: current state, new hypotheses, and limitations. | the current scenario regarding the widespread zika virus (zikv) has resulted in numerous diagnostic studies, specifically in south america and in locations where there is frequent entry of travelers returning from zikv-affected areas, including pregnant women with or without clinical symptoms of zikv infection. the world health organization, who, announced that millions of cases of zikv are likely to occur in the usa in the near future. this situation has created an alarming public health emerge ... | 2016 | 27822207 |
| characterization of a novel murine model to study zika virus. | the mosquito-borne zika virus (zikv) is responsible for an explosive ongoing outbreak of febrile illness across the americas. zikv was previously thought to cause only a mild, flu-like illness, but during the current outbreak, an association with guillain-barré syndrome and microcephaly in neonates has been detected. a previous study showed that zikv requires murine adaptation to generate reproducible murine disease. in our study, a low-passage cambodian isolate caused disease and mortality in m ... | 2016 | 27022155 |
| epidemiology of emergent madariaga encephalitis in a region with endemic venezuelan equine encephalitis: initial host studies and human cross-sectional study in darien, panama. | neurotropic arboviral infections are an important cause of encephalitis. a zoonotic, vector-borne alphavirus, madariaga virus (madv; formerly known as south american eastern equine encephalitis virus), caused its first documented human outbreak in 2010 in darien, panama, where the genetically similar venezuelan equine encephalitis virus (veev) is endemic. we report the results of a seroprevalence survey of animals and humans, illustrating contrasting features of madv and veev ecology and epidemi ... | 2016 | 27101567 |
| the role of the membrane in the structure and biophysical robustness of the dengue virion envelope. | the dengue virion is surrounded by an envelope of membrane proteins surrounding a lipid bilayer. we have combined the cryoelectron microscopy structures of the membrane proteins (pdb: 3j27) with a lipid bilayer whose composition is based on lipidomics data for insect cell membranes, to obtain a near-atomic resolution computational model of the envelope of the dengue virion. a coarse-grained molecular dynamics simulation on the microsecond timescale enables analysis of key biophysical properties ... | 2016 | 26833387 |
| intra-epidemic evolutionary dynamics of a dengue virus type 1 population reveal mutant spectra that correlate with disease transmission. | dengue virus (denv) is currently the most prevalent mosquito-borne viral pathogen. denvs naturally exist as highly heterogeneous populations. even though the descriptions on denv diversity are plentiful, only a few studies have narrated the dynamics of intra-epidemic virus diversity at a fine scale. such accounts are important to decipher the reciprocal relationship between viral evolutionary dynamics and disease transmission that shape dengue epidemiology. in the current study, we present a mic ... | 2016 | 26940650 |
| zika virus and its implication in transfusion safety. | 2016 | 26969782 | |
| transcriptome analysis of the midgut of the chinese oak silkworm antheraea pernyi infected with antheraea pernyi nucleopolyhedrovirus. | the antheraea pernyi nucleopolyhedrovirus (apnpv) is an exclusive pathogen of a. pernyi. the intense interactions between apnpv and a. pernyi cause a series of physiological and pathological changes to a. pernyi. however, no detailed report exists regarding the molecular mechanisms underlying the interactions between apnpv and a. pernyi. in this study, four cdna libraries of the a. pernyi midgut, including two apnpv-infected groups and two control groups, were constructed for transcriptomic anal ... | 2016 | 27820844 |
| prolonged shedding of chikungunya virus in semen and urine: a new perspective for diagnosis and implications for transmission. | we report the presence of chikungunya (chikv) rna in the blood, urine and semen during the acute phase of the disease in an adult with a dual infection with dengue virus type 3. the patient, a 25 yr-old man from salvador, brazil, reported a 6-day duration of high fever, arthralgia, myalgia, headache and photophobia.blood and semen specimens were positive for chikv in the first collected samples; semen and urine specimens were positive for chikv after 30 days of symptoms onset. denv-3 rna was pos ... | 2016 | 27882301 |
| genome sequence of dengue virus 3 from the pythium insidiosum transcriptomes. | 2016 | 27379056 | |
| zika virus: new clinical syndromes and its emergence in the western hemisphere. | zika virus (zikv) had remained a relatively obscure flavivirus until a recent series of outbreaks accompanied by unexpectedly severe clinical complications brought this virus into the spotlight as causing an infection of global public health concern. in this review, we discuss the history and epidemiology of zikv infection, recent outbreaks in oceania and the emergence of zikv in the western hemisphere, newly ascribed complications of zikv infection, including guillain-barré syndrome and microce ... | 2016 | 26962217 |
| the global spread of zika virus: is public and media concern justified in regions currently unaffected? | zika virus, an aedes mosquito-borne flavivirus, is fast becoming a worldwide public health concern following its suspected association with over 4000 recent cases of microcephaly among newborn infants in brazil. | 2016 | 27093860 |
| zika virus: the latest newcomer. | since the beginning of this century, humanity has been facing a new emerging, or re-emerging, virus threat almost every year: west nile, influenza a, avian flu, dengue, chikungunya, sars, mers, ebola, and now zika, the latest newcomer. zika virus (zikv), a flavivirus transmitted by aedes mosquitoes, was identified in 1947 in a sentinel monkey in uganda, and later on in humans in nigeria. the virus was mainly confined to the african continent until it was detected in south-east asia the 1980's, t ... | 2016 | 27148186 |
| clinical and epidemiological characterization of laboratory-confirmed autochthonous cases of zika virus disease in mexico. | since 2014, autochthonous circulation of zika virus (zikv) in the americas was detected (easter island, chile). in may 2015, brazil confirmed autochthonous --transmission and in october of that year colombia reported their first cases. now more than 52 countries have reported cases, including mexico. to deal with this contingency in mexico, several surveillance systems, in addition to systems for vector-borne diseases were strengthened with the participation of all health institutions. also, th ... | 2016 | 27158557 |
| computational approach towards exploring potential anti-chikungunya activity of selected flavonoids. | chikungunya virus (chikv) is a mosquito-borne alphavirus that causes chikungunya infection in humans. despite the widespread distribution of chikv, no antiviral medication or vaccine is available against this virus. therefore, it is crucial to find an effective compound to combat chikv. we aimed to predict the possible interactions between non-structural protein 3 (nsp) of chikv as one of the most important viral elements in chikv intracellular replication and 3 potential flavonoids using a comp ... | 2016 | 27071308 |
| zika virus infections imported from brazil to portugal, 2015. | zika virus is an emerging arbovirus transmitted by aedes sp. mosquitoes like the dengue and chikungunya viruses. zika virus was until recently considered a mild pathogenic mosquito-borne flavivirus with very few reported benign human infections. in 2007, an epidemic in micronesia initiated the turnover in the epidemiological history of zika virus and more recently, the potential association with congenital microcephaly cases in brazil 2015, still under investigation, led the world health organiz ... | 2016 | 27134823 |
| estimating risks of importation and local transmission of zika virus infection. | background. an international spread of zika virus (zikv) infection has attracted global attention. zikv is conveyed by a mosquito vector, aedes species, which also acts as the vector species of dengue and chikungunya viruses. methods. arrival time of zikv importation (i.e., the time at which the first imported case was diagnosed) in each imported country was collected from publicly available data sources. employing a survival analysis model in which the hazard is an inverse function of the effec ... | 2016 | 27069825 |
| identify-isolate-inform: a tool for initial detection and management of zika virus patients in the emergency department. | first isolated in 1947 from a monkey in the zika forest in uganda, and from mosquitoes in the same forest the following year, zika virus has gained international attention due to concerns for infection in pregnant women potentially causing fetal microcephaly. more than one million people have been infected since the appearance of the virus in brazil in 2015. approximately 80% of infected patients are asymptomatic. an association with microcephaly and other birth defects as well as guillain-barre ... | 2016 | 27330653 |
| recombinant dengue 2 virus ns3 helicase protein enhances antibody and t-cell response of purified inactivated vaccine. | dengue virus purified inactivated vaccines (piv) are highly immunogenic and protective over the short term, but may be poor at inducing cell-mediated immune responses and long-term protection. the dengue nonstructural protein 3 (ns3) is considered the main target for t-cell responses during viral infection. the amino (n)-terminal protease and the carboxy (c)-terminal helicase domains of denv-2 ns3 were expressed in e. coli and analyzed for their immune-potentiating capacity. mice were immunized ... | 2016 | 27035715 |
| zika virus: diagnostics for an emerging pandemic threat. | zika virus (zikv) is anaedesmosquito-borne flavivirus that emerged in brazil in 2015 and then rapidly spread throughout the tropical and subtropical americas. based on clinical criteria alone, zikv cannot be reliably distinguished from infections with other pathogens that cause an undifferentiated systemic febrile illness, including infections with two common arboviruses, dengue virus and chikungunya virus. this minireview details the methods that are available to diagnose zikv infection. | 2016 | 26888897 |
| maternal antibody-mediated disease enhancement in type i interferon-deficient mice leads to lethal disease associated with liver damage. | epidemiological studies have reported that most of the severe dengue cases occur upon a secondary heterologous infection. furthermore, babies born to dengue immune mothers are at greater risk of developing severe disease upon primary infection with a heterologous or homologous dengue virus (denv) serotype when maternal antibodies reach sub-neutralizing concentrations. these observations have been explained by the antibody mediated disease enhancement (ade) phenomenon whereby heterologous antibod ... | 2016 | 27007501 |
| nucleotide composition of the zika virus rna genome and its codon usage. | rna viruses have genomes with a distinct nucleotide composition and codon usage. we present the global characteristics of the rna genome of zika virus (zikv), an emerging pathogen within the flavivirus genus. zikv was first isolated in 1947 in uganda, caused a widespread epidemic in south and central america and the caribbean in 2015 and has recently been associated with microcephaly in newborns. | 2016 | 27278486 |
| pathogenesis of zika virus-associated embryopathy. | a strong causal association has become evident between zika virus (zikv) infection during pregnancy and the occurrence of fetal growth restriction, microcephaly and eye defects. circumstantial evidence is presented in this paper in support of the hypothesis that these effects, as well as the guillain-barré syndrome, are due to an endogenous form of hypervitaminosis a resulting from zikv infection-induced damage to the liver and the spillage of stored vitamin a compounds ("retinoids") into the ma ... | 2016 | 27403405 |
| long-term safety and immunogenicity of a tetravalent live-attenuated dengue vaccine and evaluation of a booster dose administered to healthy thai children. | we evaluated the safety and immunogenicity of two doses of a live-attenuated, tetravalent dengue virus vaccine (f17/pre formulation) and a booster dose in a dengue endemic setting in two studies. seven children (7- to 8-year-olds) were followed for 1 year after dose 2 and then given a booster dose (f17/pre formulation), and followed for four more years (child study). in the infant study, 49 2-year-olds, vaccinated as infants, were followed for approximately 3.5 years after dose 2 and then given ... | 2016 | 27022153 |
| scoping review of the zika virus literature. | the global primary literature on zika virus (zikv) (n = 233 studies and reports, up to march 1, 2016) has been compiled using a scoping review methodology to systematically identify and characterise the literature underpinning this broad topic using methods that are documented, updateable and reproducible. our results indicate that more than half the primary literature on zikv has been published since 2011. the articles mainly covered three topic categories: epidemiology of zikv (surveillance an ... | 2016 | 27244249 |
| quantifying the epidemiological impact of vector control on dengue. | 2016 | 27227829 | |
| a pan-dengue virus reverse transcription-insulated isothermal pcr assay intended for point-of-need diagnosis of dengue virus infection by use of the pockit nucleic acid analyzer. | dengue virus (denv) infection is considered a major public health problem in developing tropical countries where the virus is endemic and continues to cause major disease outbreaks every year. here, we describe the development of a novel, inexpensive, and user-friendly diagnostic assay based on a reverse transcription-insulated isothermal pcr (rt-iipcr) method for the detection of all four serotypes of denv in clinical samples. the diagnostic performance of the newly established pan-denv rt-iipc ... | 2016 | 27030492 |
| determinants of arbovirus vertical transmission in mosquitoes. | vertical transmission (vt) and horizontal transmission (ht) of pathogens refer to parental and non-parental chains of host-to-host transmission. combining ht with vt enlarges considerably the range of ecological conditions in which a pathogen can persist, but the factors governing the relative frequency of each transmission mode are poorly understood for pathogens with mixed-mode transmission. elucidating these factors is particularly important for understanding the epidemiology of arthropod-bor ... | 2016 | 27171170 |
| physicians, primary caregivers and topical repellent: all under-utilised resources in stopping dengue virus transmission in affected households. | primary health care facilities frequently manage dengue cases on an ambulatory basis for the duration of the patient's illness. there is a great opportunity for specific messaging, aimed to reduce dengue virus (denv) transmission in and around the home, to be directly targeted toward this high-risk ambulatory patient group, as part of an integrated approach to dengue management. the extent however, to which physicians understand, and can themselves effectively communicate strategies to stop foca ... | 2016 | 27164168 |
| coeloconic sensilla on the antennae of the yellow fever mosquito, aedes aegypti (l.). | 2016 | 5026452 | |
| [updating the larval habitats of aedes aegypti (diptera: culicidae) in camagüey, cuba]. | several illnesses of vectorial origin have a great medical and veterinary relevance, due to the adaptations developed by the species involved in their transmission. to support preventive programs with updated ecological information of ae. aegypti populations, an entomological survey was carried out in three health areas of camagüey, cuba, during low and high rain seasons of 2013. for this, we assessed the type and number of positive containers, quantified larvae and pupae in positive containers, ... | 2016 | 29465911 |
| chemical composition, antioxidant, antimicrobial and insecticidal activities of essential oil from a moroccan endemic plant: bubonium imbricatum. | the chemical composition, antioxidant, antimicrobial and insecticidal properties of essential oil obtained by hydro-distillation from bubonium imbricatum cav. have been investigated. the essential oil of aerial parts was analyzed by gc-fid and gc-ms. a total of 63 compounds were identified representing more than 82% of the oil. the major components were cis-chrysanthenyl acetate (31.2%) and thymol isobutyrate (3.4%). the antioxidant activity was evaluated by the dpph and reducing power test. the ... | 2016 | 30475515 |
| lantana montevidensis essential oil: chemical composition and mosquito repellent activity against aedes aegypti. | the essential oil (eo) of lantana montevidensis (spreng.) briq. (l. sellowiana link & otto) was investigated for its chemical composition and mosquito repellent activity. the essential oil obtained by hydrodistillation of aerial plant parts was analyzed by gc-fid and gc-ms. the major constituents were p-elemene (22.0%), β-caryophyllene (20.1%), and germacrene d (9.4%). sesquiterpene hydrocarbons were present.in considerable quantities (78.9%) in the l. montevidensis eo, followed by oxygenated se ... | 2016 | 30475514 |
| toxicity of compounds isolated from white snakeroot (ageratina altissima) to adult and larval yellow fever mosquitoes (aedes aegypti). | botanicals have been the source for several classes of pesticides for mosquitoes. however, increasing resistance to these products and reduced numbers of choices necessitate the search for new active ingredients. ageratina altissima (l.) king & h. rob. or white snakeroot, is found throughout the eastern united states and contains known toxic compounds. we examine chromenes (benzopyrans) and benzofurans isolated fiom this plant for larvicidal and adulticidal activity against the dengue vector aed ... | 2016 | 30475505 |
| preparative capillary gc for characterization of five dracocephalum essential oils from mongolia, and their mosquito larvicidal activity. | the chemical composition and mosquito larvicidal and adulticidal activity of five essential oils (eos), dracocephalum ruyschiana l. (dr), d. foetidum bunge (df), d. moldavica l. (dm), d. fruticulosum steph. ex willd. (dfr) and d. peregrinum l. (dp) were evaluated. simultaneous gc-fid and gc-ms analyses revealed in the eos of dr, df and dm an unidentified compound (1) ([m'122], 5.4%, 57.9% and 74.0%, respectively). therefore, we aimed to isolate compound 1 using preparative capillary gc (pcgc) co ... | 2016 | 30549618 |
| chemical composition and biting deterrent activity of essential oil of tagetes patula (marigold) against aedes aegypti. | the hydrodistilled leaf essential oil (eo) of tagetes patula l. was analyzed by gc-fid and gc-ms. the main components of the oil were characterized as caryophyllene oxide (18.4%), p-caryophyllene (18.0%) and spathulenol (9.1%). the eo was screened for its biting deterrent activity against aedes aegypti l. using the in vitro k&d module system. t. patula eo exhibited good biting deterrent activity. the results suggest that these sesquiterpenes may contribute to biting deterrent activity, but the r ... | 2016 | 30549616 |
| essential oil composition of pimpinella cypria and its insecticidal, cytotoxic, and antimicrobial activity. | a water-distilled essential oil (e) from the aerial parts of pimpinella cypria boiss. (apiaceae), an endemic species in northern cyprus, was analyzed by gc- fid and gc-ms. forty-five compounds were identified in the oil, which comprised 81.7% of the total composition. the compound classes in the oil were oxygenated sesquiterpenes (33.9%), sesquiterpenes (22.0%), monoterpenes (11.4%), oxygenated monoterpenes (2.6%), and phenylpropanoids (7.5%). the main components of the oil were (z)-β-farnesene ... | 2016 | 30549615 |
| 11-hydroxy-2,4-cycloeudesmane from the leaf oil of juglans regia and evaluation of its larvicidal activity. | leaves of juglans regia l. collected from two different locations [adana (a) and ankara (b)] from turkey were subjected to hydrodistillation in a clevenger type apparatus to yield the essential oils (eos). gc/ms and gc-fid analyses revealed that the a eo was rich in thymol (23.1%), while caryophyllene oxide (33.8%) was found as the main constituent of b eo. both contained p-eudesmol (1.4% - 9.5 %), (e)-geranyl acetone (3.7% - 5.8%) and the eudesmane type constituent juglaterpene a (3.1% - 11.0%) ... | 2016 | 30549590 |
| repellent and insecticidal efficacy of a combination of dinotefuran, pyriproxyfen and permethrin (vectra® 3d) against culex pipiens in dogs. | culex pipiens is an important vector of pathogens of substantial medical and veterinary importance such as dirofilaria immitis and dirofilaria repens or the west nile virus. the control of these mosquitoes is therefore essential to control the transmission of mosquito-borne agents to humans and animals. a combination of dinotefuran, permethrin and pyriproxyfen (vectra® 3d) has already shown its efficacy against aedes aegypti. the aim of this study was to confirm the efficacy of this combination ... | 2016 | 29988200 |
| [construction of aaldv-3 mediated mirrna sponge delivery system and its effect on cell and larva of aedes aegypti]. | micrornas (mirnas) not only play the key roles in regulation of the growth and development of mosquito, but also has an important function in interaction between the pathogen and vector. so, mirnas can be used as the molecular target for development of an alternative method for mosquito and mosquito-borne disease control. however, an effective delivery system is still need. mosquito densovirus have the potential for vector control as transducing agents to express foreign toxins or small interfer ... | 2016 | 29979549 |
| bioefficacy of ecbolin a and ecbolin b isolated from ecbolium viride (forsk.) alston on dengue vector aedes aegypti l. (diptera: culicidae). | ecbolin a and ecbolin b were isolated from ethyl acetate extract of ecbolium viride (forsk.) alston root and evaluated for larvicidal and growth disturbance activities against aedes aegypti l. (diptera: culicidae). for larvicidal activity, the third instar larvae of a. aegypti were exposed to different concentrations viz., 1.0, 2.5, 5.0 and 10 ppm for each compound. among the two compounds screened, ecbolin b recorded highest larvicidal activity with lc50 and lc90 values of 0.70 and 1.42 ppm, re ... | 2016 | 29988190 |
| effect of gamma radiation on life history traits of aedes aegypti (l.). | aedes aegypti is an important vector for dengue and dengue hemorrhagic fever. considering its medical importance and its relevance as a model system, this study was undertaken to evaluate the impact of different doses of gamma radiation for three generations of a. aegypti. two to three days old virgin males of a. aegypti were irradiated with 15 doses of gamma radiation, ranging from 1 to 50 gy and were immediately mass mated with the same aged virgin females. observations were made for changes o ... | 2016 | 29988174 |
| [identification and expression of the yellow gene family in aedes aegypti]. | to identify the yellow family genes in aedes aegypti and analyze the gene structure, phylogenetic evolution and their expression at various developmental stages and in different tissues. | 2016 | 30120914 |
| dengue fever outbreaks in eritrea, 2005-2015: a case for strengthening surveillance, control and reporting. | the geographic distribution and burden of dengue is increasing globally. this study aims to evaluate dengue outbreaks and to substantiate the need for strengthened surveillance, reporting and control in eritrea. | 2016 | 29202065 |
| phylogenetic analysis of aedes aegypti based on mitochondrial nd4 gene sequences in almadinah, saudi arabia. | aedes aegypti is the main vector of the yellow fever and dengue virus. this mosquito has become the major indirect cause of morbidity and mortality of the human worldwide. dengue virus activity has been reported recently in the western areas of saudi arabia. there is no vaccine for dengue virus until now, and the control of the disease depends on the control of the vector. | 2016 | 28959327 |
| knowledge, attitudes, and practices regarding dengue infection among public sector healthcare providers in machala, ecuador. | dengue fever is a rapidly emerging infection throughout the tropics and subtropics with extensive public health burden. adequate training of healthcare providers is crucial to reducing infection incidence through patient education and collaboration with public health authorities. we examined how public sector healthcare providers in a dengue-endemic region of ecuador view and manage dengue infections, with a focus on the 2009 world health organization (who) dengue guidelines. | 2016 | 28883952 |
| whatch'em: a weather-driven energy balance model for determining water height and temperature in container habitats for aedes aegypti. | the mosquito virus vector aedes (ae.) aegypti exploits a wide range of containers as sites for egg laying and development of the immature life stages, yet the approaches for modeling meteorologically sensitive container water dynamics have been limited. this study introduces the water height and temperature in container habitats energy model (whatch'em), a state-of-the-science, physically based energy balance model of water height and temperature in containers that may serve as development sites ... | 2016 | 29123363 |
| [findings on the biology of culicidae in hanoï (tonkin, north vietnam). i. comparative larval development of various strains of aedes albopictus, aedes aegypti, culex fatigans & armigeres obturans]. | 2016 | 13559861 | |
| [increased artificial resistance to ddt in adult aedes aegypti by contact of larvae with the insecticide]. | 2016 | 13585041 | |
| [aedes aegypti eradication campaign in chile]. | 2016 | 12977855 | |
| optimal repellent usage to combat dengue fever. | dengue fever is one of the most important vector-borne diseases. it is transmitted by aedes stegomyia aegypti, and one of the most effective strategies to combat the disease is the reduction of exposure to bites of these mosquitoes. in this paper, we present a game-theoretical model in which individuals choose their own level of protection against mosquito bites in order to maximize their own benefits, effectively balancing the cost of protection and the risk of contracting the dengue fever. we ... | 2016 | 27142427 |
| [effect of pyriproxyfen for the aedes (s) aegypti control (diptera: culicidae) in strains with various degrees of temephos resistance]. | the continuous use of the organophosphate temephos for aedes (stegomyia) aegypti (linnaeus, 1762) has prompted the emergence of resistance to this product in several countries. pyriproxyfen is an analogue of the juvenile hormone recommended by the world health organization as one of the alternative regulators of the dengue vector in drinking waters. | 2016 | 23437553 |
| comparison of two detailed models of aedes aegypti population dynamics. | the success of control programs for mosquito borne diseases can be enhanced by crucial information provided by models of the mosquito populations. models, however, can differ in their structure, complexity and biological assumptions, and these differences impact their predictions. unfortunately, it is typically difficult to determine why two complex models make different predictions because we lack structured side-by-side comparisons of models using comparable parameterization. here we present a ... | 2016 | 28462011 |
| [limits of the possibilities of acquisition of resistance to ddt of a strain of aedes aegypti subjected to known larval selection for 11 successive generations]. | 2016 | 13886805 | |
| [the ability of sumah virus of the ukuniemi group to reproduce in aedes aegypti mosquitoes]. | 2016 | 5141615 | |
| chikungunya fever. rheumatic manifestations of an emerging disease in europe. | chikungunya fever is a viral disease caused by an alphavirus belonging to the togaviridae family, transmitted by several species of aedes mosquitoes: aedes aegypti and aedes albopictus (a. albopictus). it is endemic in africa and asia with recurrent outbreaks. it is an emerging disease and cases in europe transmitted by a. albopictus have been established in mediterranean areas. the first autochthonous cases detected on the caribbean islands suppose a serious threat of spreading disease to ameri ... | 2016 | 25192946 |
| subacute toxicity assessment of diflubenzuron, an insect growth regulator, in adult male rats. | diflubenzuron (dfb), an insecticide and acaricide insect growth regulator, can be used in agriculture against insect predators and in public health programs, to control insects and vectors, mainly aedes aegypti larvae. due to the lack of toxicological assessments of this compound, the objective of the present study was to evaluate the toxicological effects of subacute exposure to the dfb insecticide in adult male rats. adult male rats were exposed (gavage) to 0, 2, 4, or 8 mg/kg of dfb for 28 da ... | 2016 | 25266294 |
| utilization of biodiesel by-products for mosquito control. | the current paper has elaborated the efficient utilization of non-edible oil seed cakes (neoc), by-products of the bio-diesel extraction process to develop a herbal and novel mosquitocidal composition against the aedes aegypti larvae. the composition consisted of botanical active ingredients, inerts, burning agents and preservatives; where the botanical active ingredients were karanja (pongamia glabra) cake powder and jatropha (jatropha curcas) cake powder, products left after the extraction of ... | 2016 | 26296531 |
| the epidemiology of dengue fever in saudi arabia: a systematic review. | dengue fever (df) is the most serious mosquito-borne viral disease worldwide. df is an acute febrile illness caused by aedes aegypti and aedes albopictus, which are endemic in certain cities of saudi arabia, such as jeddah and makkah (mecca). an online literature search was conducted using relevant keywords to retrieve df studies conducted in saudi arabia. forty-five articles were identified initially. after screening for exclusion and retrieving full texts, a total of 10 articles were used for ... | 2016 | 26106040 |
| first report of l1014f kdr mutation in culex quinquefasciatus in mexico. | the l1014f mutation in the voltage-sodium channel gene has been associated with resistance to ddt and pyrethroids in various arthropod species including mosquitoes. we determined the frequency of the l1014f kdr mutation in 16 field populations of culex quinquefasciatus from northeastern mexico collected between 2008 and 2013. the l1014f was present in all populations analyzed with the lowest frequency (3.33%) corresponding to the population from monclova collected in 2012, and the highest freque ... | 2016 | 25765734 |
| rapid biosynthesis of silver nanoparticles using crotalaria verrucosa leaves against the dengue vector aedes aegypti: what happens around? an analysis of dragonfly predatory behaviour after exposure at ultra-low doses. | aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. here, we biosynthesised mosquitocidal silver nanoparticles (agnp) using the aqueous leaf extract of crotalaria verrucosa. the green synthesis of agnp was studied by uv-vis spectroscopy, sem, edx and ftir. c. verrucosa-synthesised agnps were toxic against a. aegypti larvae and pupae. lc50 of agnp ranged from 3.496 ppm (i instar larvae) to 17.700 ppm (pupae). furthermore, we eval ... | 2016 | 26284510 |
| differentiation of aedes aegypti and aedes notoscriptus (diptera: culicidae) eggs using scanning electron microscopy. | aedes notoscriptus and aedes aegypti are both peri-domestic, invasive container-breeding mosquitoes. while the two potential arboviral vectors are bionomically similar, their sympatric distribution in australia is limited. in this study, analyses of ae. aegypti and ae. notoscriptus eggs were enabled using scanning electron microscopy. significant variations in egg length to width ratio and outer chorionic cell field morphology between ae. aegypti and ae. notoscriptus enabled distinction of the t ... | 2016 | 26845557 |
| characterization of enzymatic profiles of aedes aegypti strains from the state of rio grande do norte, brazil. | this study was conducted in four strains of aedes aegypti mosquitoes to evaluate the enzymatic activity profiles in the city of mossoró, rio grande do norte, and correlate them with biochemical mechanisms of resistance to insecticides. mosquitos were used to quantify the following detoxification enzymes: mixed-function oxidase (mfo), pnpa-esterase (pnpa-est), and acetylcholinesterase (ache). the profiles were compared statistically with profiles from the rockefeller strain, through the kruskal-w ... | 2016 | 26816185 |
| aedes aegypti (l.) in latin american and caribbean region: with growing evidence for vector adaptation to climate change? | within latin america and the caribbean region the impact of climate change has been associated with the effects of rainfall and temperature on seasonal outbreaks of dengue but few studies have been conducted on the impacts of climate on the behaviour and ecology of aedes aegypti mosquitoes.this study was conducted to examine the adaptive behaviours currently being employed by a. aegypti mosquitoes exposed to the force of climate change in lac countries. the literature on the association between ... | 2016 | 26796862 |
| effect of cymbopogon citratus (lemongrass) and syzygium aromaticum (clove) oils on the morphology and mortality of aedes aegypti and anopheles dirus larvae. | cymbopogon citratus (lemongrass) and syzygium aromaticum (clove) oils were evaluated to determine mortality rates, morphological aberrations, and persistence when used against third and fourth larval instars of aedes aegypti and anopheles dirus. the oils were evaluated at 1, 5, and 10 % concentrations in mixtures with soybean oil. persistence of higher concentrations was measured over a period of 10 days. for ae. aegypti, both plant oils caused various morphological aberrations to include deform ... | 2016 | 26796022 |
| delivery of chitosan/dsrna nanoparticles for silencing of wing development vestigial (vg) gene in aedes aegypti mosquitoes. | rna interference (rnai) has been used as a gene silencing strategy by the introduction of long double stranded rna (dsrna) for the control of pest insects. the aim of the present study was to examine whether the expression of vg gene which is responsible for wing development, can be repressed by chitosan/dsrna based nanoparticles in aedes aegypti. the vestigial gene (vg) was amplified from adult mosquito and cloned in plitmus28i vector. genetically engineered recombinant plasmid was transformed ... | 2016 | 26794313 |
| larvicidal and repellent potential of zingiber nimmonii (j. graham) dalzell (zingiberaceae) essential oil: an eco-friendly tool against malaria, dengue, and lymphatic filariasis mosquito vectors? | mosquitoes (diptera: culicidae) are important vectors of terms of public health relevance, especially in tropical and sub-tropical regions. the continuous and indiscriminate use of conventional pesticides for the control of mosquito vectors has resulted in the development of resistance and negative impacts on non-target organisms and the environment. therefore, there is a need for development of effective mosquito control tools. in this study, the larvicidal and repellent activity of zingiber ni ... | 2016 | 26792432 |
| exploiting intimate relationships: controlling mosquito-transmitted disease with wolbachia. | mosquito-transmitted diseases impose a growing burden on human health, and current control strategies have proven insufficient to stem the tide. the bacterium wolbachia is a novel and promising form of control for mosquito-transmitted disease. it manipulates host biology, restricts infection with dengue and other pathogens, and alters host reproduction to promote rapid spread in the field. in this review, we examine how the intimate and diverse relationships formed between wolbachia and their mo ... | 2016 | 26776329 |
| calcium influx enhances neuropeptide activation of ecdysteroid hormone production by mosquito ovaries. | a critical step in mosquito reproduction is the ingestion of a blood meal from a vertebrate host. in mosquitoes like aedes aegypti, blood feeding stimulates the release of ovary ecdysteroidogenic hormone (oeh) and insulin-like peptide 3 (ilp3). this induces the ovaries to produce ecdysteroid hormone (ecd), which then drives egg maturation. in many immature insects, prothoracicotropic hormone (ptth) stimulates the prothoracic glands to produce ecd that directs molting and metamorphosis. the recep ... | 2016 | 26772671 |
| temporal genetic stability of stegomyia aegypti (= aedes aegypti) populations. | the mosquito stegomyia aegypti (= aedes aegypti) (diptera: culicidae) is the primary vector of viruses that cause yellow fever, dengue and chikungunya fever. in the absence of effective vaccines, the reduction of these diseases relies on vector control strategies. the success of these strategies is tightly linked to the population dynamics of target populations. in the present study, 14 collections from st. aegypti populations separated by periods of 1-13 years were analysed to determine their t ... | 2016 | 26744174 |
| detection of aedes aegypti, aedes albopictus, and aedes koreicus in the area of sochi, russia. | following the identification of aedes (ae.) aegypti in the sochi area in russia at the beginning of 2000, entomological surveys were conducted during the summers of 2007, 2011, and 2012, leading to the identification of ae. albopictus and ae. koreicus. these findings highlight russia as being the only country in the world health organization european region with a documented presence of both ae. aegypti and ae. albopictus mosquitoes. both mosquito species are found on the coasts of the black sea ... | 2016 | 26741323 |
| bioactivity and laundering resistance of five commercially available, factory-treated permethrin-impregnated fabrics for the prevention of mosquito-borne diseases: the need for a standardized testing and licensing procedure. | personal protective measures against hematophagous vectors constitute the first line of defense against arthropod-borne diseases. in this regard, a major advance has been the development of residual insecticides that can be impregnated into clothing. currently, however, information on specific treatment procedures, initial insecticide concentrations, arthropod toxicity, residual activity, and laundering resistance is either fragmentary or non-existent, and no world health organization pesticides ... | 2016 | 26738734 |
| species distribution modelling of aedes aegypti in two dengue-endemic regions of pakistan. | statistical tools are effectively used to determine the distribution of mosquitoes and to make ecological inferences about the vector-borne disease dynamics. in this study, we utilised species distribution models to understand spatial patterns of aedes aegypti in two dengue-prevalent regions of pakistan, lahore and swat. species distribution models can potentially indicate the probability of suitability of ae. aegypti once introduced to new regions like swat, where invasion of this species is a ... | 2016 | 26729239 |
| determination of insecticidal effect (lc50 and lc90) of organic fatty acids mixture (c8910+silicone) against aedes aegypti and aedes albopictus (diptera: culicidae). | emerging and re-emerging vector-borne diseases such as chikungunya and dengue and associated aedes vectors are expanding their historical ranges; thus, there is a need for the development of novel insecticides for use in vector control programs. the mosquito toxicity of a novel insecticide and repellent consisting of medium-chain carbon fatty acids (c8910) was examined. determination of lc50 and lc90 was made against colony-reared aedes aegypti (l.) and aedes albopictus (skuse) using probit anal ... | 2016 | 26718717 |
| wolbachia restricts insect-specific flavivirus infection in aedes aegypti cells. | mosquito-borne viruses are known to cause disease in humans and livestock and are often difficult to control due to the lack of specific antivirals and vaccines. the wolbachia endosymbiont has been widely studied for its ability to restrict positive-strand rna virus infection in mosquitoes, although little is known about the precise antiviral mechanism. in recent years, a variety of insect-specific viruses have been discovered in mosquitoes and an interaction with mosquito-borne viruses has been ... | 2016 | 27692043 |