Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| evidence of vertical transmission and co-circulation of chikungunya and dengue viruses in field populations of aedes aegypti (l.) from guerrero, mexico. | we report results of the entomo-virological surveillance system in aedes aegypti local populations performed by the ministry of health of guerrero. | 2016 | 26711697 |
| synthesis and biological evaluation of 3,5-dimethoxystilbene analogs. | in our continuing effort to discover natural product-based pest management agents, derivatives of 3,5-dimethoxystilbene were synthesized yielding 27 new and six known compounds. compounds 11 and 12 showed strong aedes aegypti larvicidal activity (lc50 45.31 and 49.93 μm, respectively). furthermore, 11 and 12 exhibited high effectiveness against larvae of pesticide-susceptible and pyrethroid-resistant strains of ae. aegypti; activity against the adult mosquitoes was low. compounds 6f, 6g, and 6i ... | 2016 | 27450661 |
| dengue: an analysis of epidemiological pattern over a six year period. | dengue is an arboviral infection transmitted among humans by aedes aegypti, the urban vector and aedes albopictus as a maintenance vector in sub-urban and rural areas. the diagnosis is routinely established by detection of ns1 antigen and/or by igm antibodies testing. dengue infects 50-100 million cases per year worldwide with atleast half million serious cases needing hospitalization. therefore, it is necessary to keep the surveillance ongoing to timely look out for changes occurring in disease ... | 2016 | 28208855 |
| [reasons to recommend vaccination against dengue in easter island: immunization advisory committee of sociedad chilena de infectología]. | dengue was first diagnosed on easter island on year 2002 and thereafter recurrent outbreaks have occurred involving different serotypes of dengue virus. its vector, aedes aegypti has not been eliminated despite the small size of the island. conditions at the local hospital preclude adequate management of severe and hemorrhagic cases due to the absence of a critical care unit as well as no availability of platelets, or plasma units for transfusion. besides, transfer, of severely affected patients ... | 2016 | 27905629 |
| wolbachia: the selfish trojan horse in dengue control. | dengue fever has re-emerged as a major public health challenge. of late, several promising attempts have been made to control the disease with limited success. an innovative method of biological control of dengue is the use of the bacterium wolbachia. selected strains of wolbachia have been introduced into aedes aegypti to prevent transmission of dengue viruses by the vector. wolbachia prevents dengue transmission by either directly blocking the virus or by decreasing the lifespan of the vector. ... | 2016 | 27843186 |
| rise and fall of vector infectivity during sequential strain displacements by mosquito-borne dengue virus. | each of the four serotypes of mosquito-borne dengue virus (denv-1-4) comprises multiple, genetically distinct strains. competitive displacement between strains within a serotype is a common feature of denv epidemiology and can trigger outbreaks of dengue disease. we investigated the mechanisms underlying two sequential displacements by denv-3 strains in sri lanka that each coincided with abrupt increases in dengue haemorrhagic fever (dhf) incidence. first, the post-dhf strain displaced the pre-d ... | 2016 | 27500505 |
| secreted ns1 protects dengue virus from mannose-binding lectin-mediated neutralization. | flavivirus nonstructural protein 1 (ns1) is a unique secreted nonstructural glycoprotein. although it is absent from the flavivirus virion, intracellular and extracellular forms of ns1 have essential roles in viral replication and the pathogenesis of infection. the fate of ns1 in insect cells has been more controversial, with some reports suggesting it is exclusively cell associated. in this study, we confirm ns1 secretion from cells of insect origin and characterize its physical, biochemical, a ... | 2016 | 27798151 |
| evolutionary potential of the extrinsic incubation period of dengue virus in aedes aegypti. | dengue fever is the most common arboviral disease worldwide. it is caused by dengue viruses (denv) and the mosquito aedes aegypti is its primary vector. one of the most powerful determinants of a mosquito's ability to transmit denv is the length of the extrinsic incubation period (eip), the time it takes for a virus to be transmitted by a mosquito after consuming an infected blood meal. here, we repeatedly measured denv load in the saliva of individual mosquitoes over their lifetime and used thi ... | 2016 | 27530960 |
| non-human primate antibody response to mosquito salivary proteins: implications for dengue virus transmission in puerto rico. | an important step to incriminate a mosquito as a vector of a disease pathogen is finding evidence of direct contact between the mosquito and humans. typically, this is accomplished through landing/biting catches, or host blood meal analysis in engorged mosquitoes via immunologic assays. an alternate approach is to identify the presence of specific mosquito anti-saliva protein antibodies in the blood of exposed hosts. following the discovery of dengue infected, free roaming non-human primates in ... | 2016 | 27593498 |
| dengue protease substrate recognition: binding of the prime side. | dengue virus (denv), transmitted predominantly in tropical and subtropical regions by the mosquito aedes aegypti, infects millions of people and leads to dengue fever and thousands of deaths each year. there are no direct-acting antivirals to combat denv, and molecular and structural knowledge is required to develop such compounds. the dengue ns2b/ns3 protease is a promising target for direct-acting antivirals, as viral polyprotein cleavage during replication is required for the maturation of th ... | 2016 | 27657335 |
| the mysterious zika virus: adding to the tropical flavivirus mayhem. | until now, known as the demure cousin of dengue virus (denv) inhabiting africa, zika virus (zikv) has reinvented itself to cause explosive epidemics captivating the western hemisphere. the outbreak causing potential for zikv was realized when it made its way from africa to yap island micronesia in 2007, and in french polynesia in 2013. from there, it moved on to brazil in 2015. now zikv has infected people in more than 33 countries in central and south america and the caribbean. moreover the epi ... | 2016 | 27652985 |
| presence of aedes (stegomyia) aegypti (linnaeus, 1762) and its natural infection with dengue virus at unrecorded heights in colombia. | aedes aegypti is the main vector of urban yellow fever, dengue, chikungunya and zika viruses. the biogeographical distribution of this species has expanded due to global warming, and socioeconomic and cultural factors. the changes in the altitudinal distribution patterns of this vector and its natural infection are priority fields of research to develop entomological, virological and public health surveillance strategies. | 2016 | 27622492 |
| management and treatment of dengue and chikungunya - natural products to the rescue. | neglected tropical diseases (ntds) flourish mostly in impoverished developing nations of the world. it is estimated that ntds plague up to 1 billion people every year thereby inducing a massive economic and health burden worldwide. following explosive outbreaks mostly in asia, latin america, europe and the indian ocean, two common ntds namely, chikungunya and dengue both transmitted by an infected mosquito vector principally aedes aegypti have emerged as a major public health threat. given the l ... | 2016 | 27151484 |
| molecular characterization of two major dengue outbreaks in costa rica. | dengue virus (denv) (flavivirus, flaviviridae) is a reemerging arthropod-borne virus with a worldwide circulation, transmitted mainly by aedes aegypti and aedes albopictus mosquitoes. since the first detection of its main transmitting vector in 1992 and the invasion of denv-1 in 1993, costa rica has faced dengue outbreaks yearly. in 2007 and 2013, costa rica experienced two of the largest outbreaks in terms of total and severe cases. to provide genetic information about the etiologic agents prod ... | 2016 | 27139442 |
| dengue virus immunopathogenesis: lessons applicable to the emergence of zika virus. | dengue is the leading mosquito-transmitted viral infection in the world. there are more than 390 million new infections annually; while the majority of infected individuals are asymptomatic or develop a self-limited dengue fever, up to 1 million clinical cases develop severe manifestations, including dengue hemorrhagic fever and shock syndrome, resulting in ~25,000 deaths annually, mainly in children. gaps in our understanding of the mechanisms that contribute to dengue infection and immunopatho ... | 2016 | 27130436 |
| production of dengue virus envelope protein domain iii-based antigens in tobacco chloroplasts using inducible and constitutive expression systems. | dengue fever is a disease in many parts of the tropics and subtropics and about half the world's population is at risk of infection according to the world health organization. dengue is caused by any of the four related dengue virus serotypes den-1, -2, -3 and -4, which are transmitted to people by aedes aegypti mosquitoes. currently there is only one vaccine (dengvaxia(®)) available (limited to a few countries) on the market since 2015 after half a century's intensive efforts. affordable and ac ... | 2016 | 27116001 |
| effects of larval nutrition on wolbachia-based dengue virus interference in aedes aegypti (diptera: culicidae). | in order to assess the broad-scale applicability of field releases of wolbachia for the biological control of insect-transmitted diseases, we determined the relationship between the larval diet of aedes aegypti l. mosquitoes infected with wolbachia strains and their susceptibility to dengue virus (denv) infection via intrathoracic injection and oral inoculation. larvae were reared on diets that varied in the quantity of food which had the effect of modifying development time and adult body size. ... | 2016 | 27106932 |
| lethal dengue virus infection: a forensic overview. | dengue virus is a single-stranded rna virus that is a member of the family flaviviridae, genus flavivirus. it is usually transmitted by the female aedes aegypti mosquito. dengue fever is a febrile illness caused by 1 of 4 serotypes of the virus, which may progress to dengue hemorrhagic fever or dengue shock syndrome. the mortality rate of untreated dengue shock syndrome is more than 20%. the reported incidence has increased 30-fold for the past 50 years with an estimated 50 to 100 million dengue ... | 2016 | 27093563 |
| vector surveillance for dengue virus detection in the archipelago of fernando de noronha, brazil. | aedes aegypti (l.) has become an efficient vector of important arboviruses due to its anthropophilic and domiciliary behaviors. since the 1980s, dengue affects thousands of people every year in brazil; in fernando de noronha (fn), a touristic archipelago, dengue cases have occurred since 2001. once ae. aegypti populations are well established in the inhabited areas of fn, the threat of dengue or another arbovirus epidemic is continuously imminent. this study aimed to monitor the denv serotypes i ... | 2016 | 27067800 |
| mosquito vectors and the spread of cancer: an overlooked connection? | mosquitoes (diptera: culicidae) represent a key threat for millions of humans and animals worldwide, vectoring important pathogens and parasites, including malaria, dengue, filariasis, and zika virus. besides mosquito-borne diseases, cancers figure among the leading causes of mortality worldwide. it is expected that annual cancer cases will rise from 14 million in 2012 to 22 million within the next two decades. notably, there are few contrasting evidences of the relationship between cancer and m ... | 2016 | 27053131 |
| dengue virus-1 infection did not alter the behavioral response of aedes aegypti (diptera: culicidae) to deet. | no licensed vaccine or antiviral drug against dengue virus (denv) is available; therefore, most of the effort to prevent this disease is focused on reducing vector-host interactions. one of the most widely accepted methods of blocking vector-human contact is to use insect repellents to interfere with mosquito host-seeking behavior. some arboviruses can replicate in the nervous system of the vector, raising the concern that arboviral infection may alter the insect behavioral response toward chemi ... | 2016 | 27026163 |
| notes from the field: evidence of zika virus infection in brain and placental tissues from two congenitally infected newborns and two fetal losses--brazil, 2015. | zika virus is a mosquito-borne flavivirus that is related to dengue virus and transmitted primarily by aedes aegypti mosquitoes, with humans acting as the principal amplifying host during outbreaks. zika virus was first reported in brazil in may 2015 (1). by february 9, 2016, local transmission of infection had been reported in 26 countries or territories in the americas.* infection is usually asymptomatic, and, when symptoms are present, typically results in mild and self-limited illness with s ... | 2016 | 26890059 |
| the effect of temperature on wolbachia-mediated dengue virus blocking in aedes aegypti. | dengue fever, caused by dengue virus (denv), is endemic in more than 100 countries. the lack of effective treatment of patients and the suboptimal efficacies of the tetravalent vaccine in trials highlight the urgent need to develop alternative strategies to lessen the burden of dengue fever.wolbachia pipientis, an obligate intracellular bacterium, is being developed as a biocontrol strategy against dengue because it limits the replication of the denv in the mosquito vector,aedes aegypti however, ... | 2016 | 26856916 |
| aedes aegypti anti-salivary gland antibody concentration and dengue virus exposure history in healthy individuals living in an endemic area in colombia. | mosquito salivary proteins are able to induce an antibody response that reflects the level of human-vector contact. igg antibodies against dengue virus (denv-igg) are indicators of previous exposure. the risk of denv transmission is not only associated to mosquito or dengue factors, but also to socioeconomic factors that may play an important role in the disease epidemiology. | 2016 | 26844447 |
| human c5a protein participates in the mosquito immune response against dengue virus. | dengue virus (denv) is transmitted by aedes spp mosquitoes during a bloodmeal uptake. the bloodmeal consists of host cells, immune factors, and possibly blood-borne pathogens, such as arboviruses. human cells and immune-related factors, like the complement system, can remain active in the bloodmeal and may be able to interact with pathogens in the mosquito. previous studies have shown that active complement proteins impact plasmodium parasite viability in the anopheles midgut. thus, we investiga ... | 2016 | 26843451 |
| infection of mosquito cells (c6/36) by dengue-2 virus interferes with subsequent infection by yellow fever virus. | dengue is one of the most important diseases caused by arboviruses in the world. yellow fever is another arthropod-borne disease of great importance to public health that is endemic to tropical regions of africa and the americas. both yellow fever and dengue viruses are flaviviruses transmitted by aedes aegypti mosquitoes, and then, it is reasonable to consider that in a given moment, mosquito cells could be coinfected by both viruses. therefore, we decided to evaluate if sequential infections o ... | 2016 | 26808727 |
| natural transmission of dengue virus serotype 3 by aedes albopictus (skuse) during an outbreak in havelock island: entomological characteristics. | from may to june 2014, an outbreak of dengue virus (denv) illness occurred in the havelock island, south andaman. entomological investigations were undertaken during the peak of the outbreak, from 26th may-4th june, to identify the primary vector(s) involved in the transmission so that appropriate public health measures could be implemented. adult mosquitoes were collected by bg-sentinel traps in houses and neighborhoods of clinically ill patients. water holding containers were inspected for the ... | 2016 | 26780552 |
| autophagy and viral diseases transmitted by aedes aegypti and aedes albopictus. | despite a long battle that was started by oswaldo cruz more than a century ago, in 1903, brazil still struggles to fight aedes aegypti and aedes albopictus, the mosquito vectors of dengue virus (denv), chikungynya virus (chikv) and zika virus (zikv). dengue fever has been a serious public health problem in brazil for decades, with recurrent epidemic outbreaks occurring during summers. in 2015, until november, 1,534,932 possible cases were reported to the ministry of healthv. more recently, the l ... | 2016 | 26774331 |
| a native wolbachia endosymbiont does not limit dengue virus infection in the mosquito aedes notoscriptus (diptera: culicidae). | the endosymbiotic bacterium wolbachia pipientis infects many species of insects and has been transinfected into the mosquito aedes aegypti (l.), the primary vector of dengue virus (denv). recently, it has been shown that wolbachia blocks the replication and transmission of rna viruses, such as denv, in a number of mosquito species including ae. aegypti and aedes albopictus (skuse), which is naturally infected with wolbachia and considered a secondary vector for denv. the mosquito species aedes n ... | 2016 | 26721865 |
| easy and inexpensive molecular detection of dengue, chikungunya and zika viruses in febrile patients. | dengue (denv), chikungunya (chikv) and zika (zikv) are arthropod-borne viruses (arboviruses) sharing a common vector, the mosquito aedes aegypti. at initial stages, patients infected with these viruses have similar clinical manifestations, however, the outcomes and clinical management of these diseases are different, for this reason early and accurate identification of the causative virus is necessary. this paper reports the development of a rapid and specific nested-pcr for detection of denv, c ... | 2016 | 27477452 |
| larvicidal and adulticidal activity of chroman and chromene analogues against susceptible and permethrin-resistant mosquito strains. | mosquitoes play a major role as vectors that transmit parasitic and viral diseases worldwide, especially in tropical and subtropical countries. mosquito borne diseases not only affect humans but they also affect livestock in many parts of the world. they carry diseases that are lethal to dogs and horses. dog heartworm disease (dirofilaria immitis) is a parasitic disease spread through mosquitoes. this disease is not limited to dogs, but it can affect other animals and humans as well. eastern equ ... | 2016 | 27249182 |
| why zika virus infection has become a public health concern? | prior to 2015, zika virus (zikv) outbreaks had occurred in areas of africa, southeast asia, and the pacific islands. although a causal relationship between zika infection during pregnancy and microcephaly is strongly suspected, such a connection has not yet been scientifically proven. in may 2015, the outbreak of zikv infection in brazil led to reports of syndrome and pregnant women giving birth to babies with birth defects and poor pregnancy outcomes; the pan american health organization (paho) ... | 2016 | 27052792 |
| raw sewage as breeding site to aedes (stegomyia) aegypti (diptera, culicidae). | the selection of oviposition sites by females of aedes (stegomyia) aegypti is a key factor for the larval survival and egg dispersion and has a direct influence in vector control programs. in this study, we evaluated the aspects of reproductive physiology of ae. aegypti mosquitoes tested in the presence of raw sewage. ae. aegypti females were used in oviposition bioassays according to two methodologies: (i) choice assay, in which three oviposition substrates were offered in the same cage: treatm ... | 2016 | 27640323 |
| identification of aadnr1, a novel gene related to innate immunity and apoptosis in aedes albopictus. | innate immunity and apoptosis play critical roles in defending pathogens in insects. in drosophila, dnr1 was reported as a negative regulator of apoptosis and immune deficiency (imd) pathway which belongs to innate immunity. aedes albopictus is an important kind of arbovirus vector and becoming a significant threat to public health due to its rapid global expansion. here we identified an ortholog of dnr1 from a. albopictus, named as aadnr1. aadnr1 encoded a putative protein containing an n-termi ... | 2016 | 27045774 |
| characterization of a fasciola gigantica protein carrying two dm9 domains reveals cellular relocalization property. | even at the present age of whole-organism analysis, e.g., genomics, transcriptomics, and proteomics, the biological roles of many proteins remain unresolved. classified among the proteins of unknown function is a family of proteins harboring repeats of the dm9 domain, a 60-75 amino acids motif first described in a small number of drosophila melanogaster proteins. proteins may carry two or more dm9 domains either in combination with other domains or as their sole constituent. here we have charact ... | 2016 | 26946400 |
| comparative susceptibility of ochlerotatus japonicus, ochlerotatus triseriatus, aedes albopictus, and aedes aegypti (diptera: culicidae) to la crosse virus. | invasive mosquito species can increase the transmission risk of native mosquito-borne diseases by acting as novel vectors. in this study, we examined the susceptibility of three exotic invasive mosquito species aedes aegypti (l.), ae. albopictus (skuse), and ochlerotatus japonicus (theobald) to la crosse virus (lacv) relative to the native primary vector ochlerotatus triseriatus (say). adult females of the four mosquito species were orally challenged with lacv; incubated for 3, 5, 7, 9, or 11 d; ... | 2016 | 27605372 |
| antimicrobial and antileishmanial activities of diterpenoids isolated from the roots of salvia deserta. | four diterpenes with biological activity were isolated from salvia deserta roots. taxodione was considered leishmanicidal with an ic50 value of 1.46 µm (0.46 mg/l) against leishmania donovani and also exhibited antifungal and antimicrobial activities. ferruginol displayed the greatest activity [24-h ic50 of 4.5 µm (1.29 mg/l)] against the fish pathogenic bacteria streptococcus iniae. the crude extract fraction that contained the isolated compounds 7-o-acetylhorminone and horminone showed stronge ... | 2016 | 26308356 |
| uv-b radiation reduces in vitro germination of metarhizium anisopliae s.l. but does not affect virulence in fungus-treated aedes aegypti adults and development on dead mosquitoes. | control of diurnal aedes aegypti with mycoinsecticides should consider the exposure of fungus-treated adults to sunlight, and especially to uv-b radiation that might affect activity of conidia applied on the mosquito's surface. | 2016 | 27685030 |
| determination and characterization of destruxin production in metarhizium anisopliae tk6 and formulations for aedes aegypti mosquitoes control at the field level. | destruxins, cyclic hexadepsipeptide toxins, secreted by the entomopathogenic fungus, metarhizium anisopliae through extracellular synthesis. the present study reports a new approach for the analysis of dtxs produced by the fungal strain metarhizium anisoliae tk6, using frir-hplc-lc-ms and h(1) nmr. the results also showed that production of the major dtxs a, b, c, and e have to be determined in czapek dextrose (cd) liquid culture filtrate from 9 to 12 days post-inoculation. purified dtx were fur ... | 2016 | 27452930 |
| declining malaria, rising of dengue and zika virus: insights for mosquito vector control. | the fight against mosquito-borne diseases is a challenge of huge public health importance. to our mind, 2015 was an extraordinary year for malaria control, due to three hot news: the nobel prize to youyou tu for the discovery of artemisinin, the development of the first vaccine against plasmodium falciparum malaria [i.e. rts,s/as01 (rts,s)], and the fall of malaria infection rates worldwide, with special reference to sub-saharan africa. however, there are major challenges that still deserve atte ... | 2016 | 26932263 |
| mycobacterium ulcerans toxin, mycolactone may enhance host-seeking and oviposition behaviour by aedes aegypti (l.) (diptera: culicidae). | the ecological functions of many toxins continue to remain unknown for those produced by environmental pathogens. mycobacterium ulcerans, the causative agent of the neglected tropical disease, buruli ulcer, produces a cytotoxic macrolide, mycolactone, whose function(s) in the environment remains elusive. through a series of dual-choice behaviour assays, they show that mycolactone may be an interkingdom cue for the yellow fever mosquito, aedes aegypti, seeking blood-meals as well as oviposition s ... | 2016 | 27907248 |
| assessment of the ability of aedes species mosquitoes to transmit feline mycoplasma haemofelis and 'candidatus mycoplasma haemominutum'. | the objective of this study was to evaluate wild-caught mosquitoes for evidence of hemotropic mycoplasma species dna and to determine whether the feline hemoplasmas, mycoplasma haemofelis (mhf) and 'candidatus mycoplasma haemominutum' (mhm), can be transmitted by aedes aegypti mosquitoes in a laboratory setting. | 2016 | 27418288 |
| development of a sybr green i-based quantitative rt-pcr for ross river virus: application in vector competence studies and antiviral drug evaluation. | ross river virus (rrv) is an emerging alphavirus and is presently endemic in many parts of oceania. keeping in mind its emergence, we developed a molecular detection system and utilized it to study vector competence and evaluate activity of antiviral compounds against rrv. a sybr green i-based quantitative rt-pcr for detection of rrv was developed targeting the e2 gene, with a detection limit of 100 rna copies/reaction. the specificity was confirmed with closely related alphaviruses and flavivir ... | 2016 | 27105737 |
| chemical composition, antimicrobial and insecticidal activities of flowers essential oils of alpinia zerumbet (pers.) b.l.burtt & r.m.sm. from martinique island. | alpinia species, used as ornamental plants and flavoring agents, are renowned for their therapeutic properties and their subsequent use in traditional medicines throughout the world. alpinia zerumbet (pers.) b.l.burtt & r.m.sm. is the most common alpinia species encountered in martinique. several essential oils (eos) obtained by hydrodistillation of a. zerumbet flowers collected in various locations on the island at different seasons were analysed to evaluate the influence of the collection peri ... | 2016 | 27935668 |
| fighting arboviral diseases: low toxicity on mammalian cells, dengue growth inhibition (in vitro), and mosquitocidal activity of centroceras clavulatum-synthesized silver nanoparticles. | dengue is a mosquito-borne viral disease that has rapidly spread in all regions of the world in recent years. female mosquitoes, mainly aedes aegypti, transmit dengue. approximately 3,900 million people, in 128 countries, are at risk of dengue infection. recently, a focus has been provided on the potential of green-synthesized nanoparticles as inhibitors of the production of dengue viral envelope (e) protein in vero cells and downregulators of the expression of dengue viral e gene. algae are an ... | 2016 | 26462804 |
| costs and benefits of vertical and horizontal transmission of dengue virus. | parasites can be transmitted vertically and/or horizontally, but the costs or benefits for the host of infection have only been tested after horizontal transmission. here, we report for the first time, to our knowledge, the survival, reproduction and infection of aedes aegypti during vertical and horizontal transmission of dengue virus 2 (denv-2). females infected horizontally produced more eggs, with a sex ratio skewed towards males, compared with uninfected controls. however, there was no sign ... | 2016 | 27618859 |
| aedes aegypti (diptera: culicidae) longevity and differential emergence of dengue fever in two cities in sonora, mexico. | dengue virus, primarily transmitted by the aedes aegypti (l.) mosquito, has rapidly expanded in geographic extent over the past several decades. in some areas, however, dengue fever has not emerged despite established ae. aegypti populations. the reasons for this are unclear and have sometimes been attributed to socio-economic differences. in 2013 we compared ae. aegypti adult density and population age structure between two cities in sonora, mexico: hermosillo, which has regular seasonal dengue ... | 2016 | 27590231 |
| dengue infection. | dengue is widespread throughout the tropics and local spatial variation in dengue virus transmission is strongly influenced by rainfall, temperature, urbanization and distribution of the principal mosquito vector aedes aegypti. currently, endemic dengue virus transmission is reported in the eastern mediterranean, american, south-east asian, western pacific and african regions, whereas sporadic local transmission has been reported in europe and the united states as the result of virus introductio ... | 2016 | 27534439 |
| mosquito avoidance practices and knowledge of arboviral diseases in cities with differing recent history of disease. | as the range of dengue virus (denv) transmission expands, an understanding of community uptake of prevention and control strategies is needed both in geographic areas where the virus has recently been circulating and in areas with the potential for denv introduction. personal protective behaviors such as the use of mosquito repellent to limit human-vector contact and the reduction of vector density through elimination of oviposition sites are the primary control methods for aedes aegypti, the ma ... | 2016 | 27527634 |
| update: ongoing zika virus transmission - puerto rico, november 1, 2015-july 7, 2016. | zika virus is a flavivirus transmitted primarily by aedes aegypti and aedes albopictus mosquitoes, and infection can be asymptomatic or result in an acute febrile illness with rash (1). zika virus infection during pregnancy is a cause of microcephaly and other severe birth defects (2). infection has also been associated with guillain-barré syndrome (gbs) (3) and severe thrombocytopenia (4,5). in december 2015, the puerto rico department of health (prdh) reported the first locally acquired case o ... | 2016 | 27490087 |
| zika virus: a new arboviral public health problem. | zika virus (zikv) is a single-stranded rna virus in the flaviviridae family and transmitted to human through infected mosquitos (aedes aegypti and aedes albopictus). virus is closely related with other flaviviruses; dengue virus, yellow fever virus, west nile virus, and japanese encephalitis virus phylogenetically. due to the possible relationship between virus and clinical features including microcephaly, ventricule, and eye deformities, guillain-barre syndrome increases the interest on this vi ... | 2016 | 27469112 |
| apoptosis-related genes control autophagy and influence denv-2 infection in the mosquito vector, aedes aegypti. | the mosquito aedes aegypti is the primary urban vector for dengue virus (denv) worldwide. insight into interactions occurring between host and pathogen is important in understanding what factors contribute to vector competence. however, many of the molecular mechanisms for vector competence remain unknown. our previous global transcriptional analysis suggested that differential expression of apoptotic proteins is involved in determining refractoriness vs susceptibility to denv-2 infection in ae. ... | 2016 | 27418459 |
| zika virus infections: an overview of current scenario. | zika virus (zikv) was discovered more than half a century ago, recently it has gained unprecedented attention by the global health community. until 2007, only 14 cases of human zikv infections were reported around the globe, while during the current outbreak, estimated cases mounted to approximately 1.5 million in brazil alone, the virus was disseminated to wider south-american territories and travel-associated zikv infections were reported in usa, europe and recently in china. zikv infections r ... | 2016 | 27393087 |
| clinical and epidemiological characterization of the first recognized outbreak of dengue virus-type 2 in mozambique, 2014. | since the first reported epidemic of dengue in pemba, the capital of cabo delgado province, in 1984-1985, no further cases have been reported in mozambique. in march 2014, the provincial health directorate of cabo delgado reported a suspected dengue outbreak in pemba, associated with a recent increase in the frequency of patients with nonmalarial febrile illness. an investigation conducted between march and june detected a total of 193 clinically suspected dengue patients in pemba and nampula, t ... | 2016 | 26643534 |
| vector competence of aedes albopictus and aedes aegypti (diptera: culicidae) for the den2-fj10 and den2-fj11 strains of the dengue 2 virus in fujian, china. | dengue is an acute, emerging, infectious disease transmitted by aedes mosquitoes that has become a serious global public health problem. the den2-fj10 and den2-fj11 strains of the dengue 2 virus were originally isolated from the serum of a patient with dengue fever in fujian province, china, in 1999. our data provide the first assessment of the vector competence of aedes mosquitoes with respect to the den2-fj10 and den2-fj11 strains of the dengue virus. there were significant differences in the ... | 2016 | 27260668 |
| a novel mosquito ubiquitin targets viral envelope protein for degradation and reduces virion production during dengue virus infection. | dengue virus (denv) is a mosquito-borne flavivirus that causes significant human disease and mortality in the tropics and subtropics. by examining the effects of virus infection on gene expression, and interactions between virus and vector, new targets for prevention of infection and novel treatments may be identified in mosquitoes. we previously performed a microarray analysis of the aedes aegypti transcriptome during infection with denv and found that mosquito ubiquitin protein ub3881 (aael003 ... | 2016 | 27241849 |
| aphicidal activity of illicium verum fruit extracts and their effects on the acetylcholinesterase and glutathione s-transferases activities in myzus persicae (hemiptera: aphididae). | this study aims to explore the aphicidal activity and underlying mechanism of illicium verum hook. f. that is used as both food and medicine. the contact toxicity of the extracts from i. verum fruit with methyl alcohol (ma), ethyl acetate (ea), and petroleum ether (pe) against myzus persicae (sulzer), and the activities of acetylcholinesterase (ache) and glutathione s-transferases (gsts) of m. persicae after contact treatment were tested. the results showed that ma, ea, and pe extracts of 1.000 ... | 2016 | 26826651 |
| identification of the temperature induced larvicidal efficacy of agave angustifolia against aedes, culex, and anopheles larvae. | synthetic insecticides are generally employed to control the mosquito population. however, their injudicious over usage and non-biodegradability are associated with many adverse effects on the environment and mosquitoes. the application of environment-friendly mosquitocidals might be an alternate to overcome these issues. in this study, we found that organic or aqueous extracts of agave angustifolia leaves exhibited a strong larvicidal activity (ld50 28.27 μg/ml) against aedes aegypti, culex qui ... | 2016 | 26793700 |
| mosquitocidal effect of glycosmis pentaphylla leaf extracts against three mosquito species (diptera: culicidae). | the resistance status of malaria vectors to different classes of insecticides used for public health has raised concern for vector control programmes. alternative compounds to supplement the existing tools are important to be searched to overcome the existing resistance and persistence of pesticides in vectors and the environment respectively. the mosquitocidal effects of glycosmis pentaphylla using different solvents of acetone, methanol, chloroform and ethyl acetate extracts against three medi ... | 2016 | 27391146 |
| leucokinin mimetic elicits aversive behavior in mosquito aedes aegypti (l.) and inhibits the sugar taste neuron. | insect kinins (leucokinins) are multifunctional peptides acting as neurohormones and neurotransmitters. in females of the mosquito vector aedes aegypti (l.), aedeskinins are known to stimulate fluid secretion from the renal organs (malpighian tubules) and hindgut contractions by activating a g protein-coupled kinin receptor designated "aedae-kr." we used protease-resistant kinin analogs 1728, 1729, and 1460 to evaluate their effects on sucrose perception and feeding behavior. in no-choice feedin ... | 2016 | 27274056 |
| evaluation of sublethal effects of ipomoea cairica linn. extract on life history traits of dengue vectors. | plant derived insecticides have considerable potential for mosquito control because these products are safer than conventional insecticides. this study aimed to investigate sublethal activities of ipomoea carica or railway creeper crude acethonilic extract against life history trait of dengue vectors, aedes albopictus and aedes aegypti. the late third instar larvae of ae. albopictus and ae. aegypti were exposed to a sublethal dose at lc50 and larvae that survived were further cultured. overall, ... | 2016 | 27253746 |
| a novel xenomonitoring technique using mosquito excreta/feces for the detection of filarial parasites and malaria. | given the continued successes of the world's lymphatic filariasis (lf) elimination programs and the growing successes of many malaria elimination efforts, the necessity of low cost tools and methodologies applicable to long-term disease surveillance is greater than ever before. as many countries reach the end of their lf mass drug administration programs and a growing number of countries realize unprecedented successes in their malaria intervention efforts, the need for practical molecular xenom ... | 2016 | 27096156 |
| insect transformation with piggybac: getting the number of injections just right. | the insertion of exogenous genetic cargo into insects using transposable elements is a powerful research tool with potential applications in meeting food security and public health challenges facing humanity. piggybac is the transposable element most commonly utilized for insect germline transformation. the described efficiency of this process is variable in the published literature, and a comprehensive review of transformation efficiency in insects is lacking. this study compared and contrasted ... | 2016 | 27027400 |
| fabrication of metal nanoparticles from fungi and metal salts: scope and application. | fungi secrete enzymes and proteins as reducing agents which can be used for the synthesis of metal nanoparticles from metal salts. large-scale production of nanoparticles from diverse fungal strains has great potential since they can be grown even in vitro. in recent years, various approaches have been made to maximize the yield of nanoparticles of varying shape, size, and stability. they have been characterized by thermogravimetric analysis, x-ray diffractometry, sem/tem, zeta potential measure ... | 2016 | 26909778 |
| development of non-defective recombinant densovirus vectors for microrna delivery in the invasive vector mosquito, aedes albopictus. | we previously reported that mosquito densoviruses (mdvs) are potential vectors for delivering foreign nucleic acids into mosquito cells. however, considering existing expression strategies, recombinant viruses would inevitably become replication-defective viruses and lose their ability for secondary transmission. the packaging limitations of the virion represent a barrier for the development of mdvs for viral paratransgenesis or as high-efficiency bioinsecticides. herein, we report the developme ... | 2016 | 26879823 |
| an evidence-based review on medicinal plants used as insecticide and insect repellent in traditional iranian medicine. | insects can be the cause of major ecological problems; they can transmit microbes and parasites that affect humans, and damage food crops, trees, and homes. the total economic cost of insect-related damage and disease is immeasurable. in traditional iranian medicine (tim), several medicinal plants have been identified as insecticides or insect repellents, but many of them are still unknown. therefore, the aim of this study was to review the insecticidal or insect repellent activity of certain me ... | 2016 | 27186389 |
| large-scale anopheles arabiensis egg quantification methods for mass-rearing operations. | the success of the sterile insect technique relies, among other things, on the continuous release of over flooding numbers of sexually competitive sterile males into the target area. to produce sufficiently large quantities of sterile males, rearing protocols need to be optimized including the development and validation of a standardized egg quantification method. | 2016 | 26852018 |
| identification of male- and female-specific olfaction genes in antennae of the oriental fruit fly (bactrocera dorsalis). | the oriental fruit fly (bactrocera dorsalis) is a species of tephritid fruit fly, endemic to southeast asia but also introduced to many regions of the us, and it is one of the major pest species with a broad host range of cultivated and wild fruits. although males of b. dorsalis respond strongly to methyl eugenol and this is used for monitoring and estimating populations, the molecular mechanism of the oriental fruit fly olfaction has not been elucidated yet. therefore, in this project, using ne ... | 2016 | 26845547 |
| methanolic extract of agerantum conyzoides exhibited toxicity and growth disruption activities against anopheles gambiae sensu stricto and anopheles arabiensis larvae. | vector control remains the mainstay to effective malaria management. the negative implications following persistent application of synthetic insecticides geared towards regulation of mosquito populations have necessitated prospection for ecofriendly effective chemistries. plant-derived compounds have the potential to control malaria-transmitting mosquito populations. previously, agerantum conyzoides extracts have demonstrated toxicity effects on disease-transmitting mosquitoes. however, their ef ... | 2016 | 27876055 |
| identification of genes for engineering the male germline of aedes aegypti and ceratitis capitata. | synthetic biology approaches are promising new strategies for control of pest insects that transmit disease and cause agricultural damage. these strategies require characterised modular components that can direct appropriate expression of effector sequences, with components conserved across species being particularly useful. the goal of this study was to identify genes from which new potential components could be derived for manipulation of the male germline in two major pest species, the mosqui ... | 2016 | 27871244 |
| does fluoride influence oviposition of anopheles stephensi in stored water habitats in an urban setting? | the physico-chemical characteristics of lentic aquatic habitats greatly influence mosquito species in selecting suitable oviposition sites; immature development, pupation and adult emergence, therefore are considerations for their preferred ecological niche. correlating water quality parameters with mosquito breeding, as well as immature vector density, are useful for vector control operations in identifying and targeting potential breeding habitats. | 2016 | 27829419 |
| identification and characterization of micrornas expressed in the african malaria vector anopheles funestus life stages using high throughput sequencing. | over the past several years, thousands of micrornas (mirnas) have been identified in the genomes of various insects through cloning and sequencing or even by computational prediction. however, the number of mirnas identified in anopheline species is low and little is known about their role. the mosquito anopheles funestus is one of the dominant malaria vectors in africa, which infects and kills millions of people every year. therefore, small rna molecules isolated from the four life stages (eggs ... | 2016 | 27825380 |
| vorticella sp: prospective mosquito biocontrol agent. | considering the disadvantages of chemical insecticides, we aimed to evaluate vorticella parasites for control of mosquito larvae of anopheles stephensi and aedes aegypti at different larval stages. | 2016 | 28032113 |
| laboratory evaluation of temephos against anopheles stephensi and culex pipiens larvae in iran. | malaria is still a health problem in iran. there are several vector control activities, including indoor residual spraying, using insecticide treated nets and larviciding including temephos. in addition nuisance mosquitos are prevalent in the urban areas. so that evaluation of this species to larvicide will provide a clue for management of vector control activities. | 2016 | 28032103 |
| guy1 confers complete female lethality and is a strong candidate for a male-determining factor in anopheles stephensi. | despite their importance in sexual differentiation and reproduction, y chromosome genes are rarely described because they reside in repeat-rich regions that are difficult to study. here, we show that guy1, a unique y chromosome gene of a major urban malaria mosquito anopheles stephensi, confers 100% female lethality when placed on the autosomes. we show that the small guy1 protein (56 amino acids in length) causes female lethality and that males carrying the transgene are reproductively more com ... | 2016 | 27644420 |
| effects of environment, dietary regime and ageing on the dengue vector microbiota: evidence of a core microbiota throughout aedes aegypti lifespan. | mosquito midgut microbiota is a key component of vector competence, as gut bacteria can disturb pathogen development. in this study, we addressed the microbiota composition of aedes aegypti during its lifespan, under field conditions. we also investigated the possible effects of environment, dietary regime and ageing on the gut community composition. we employed culture independent and dependent approaches to characterise vector microbiota. there was evidence of a lifelong stable core microbiota ... | 2016 | 27580348 |
| seminal fluid protein genes of the brown planthopper, nilaparvata lugens. | seminal fluid proteins (sfps) are produced mainly in the accessory gland of male insects and transferred to females during mating, in which they induce numerous physiological and post-mating behavioral changes. the brown plant hopper (bph), nilaparvata lugens, is an economically important hemipterous pest of rice. the behavior and physiology of the female of this species is significantly altered by mating. sfps in hemipteran species are still unclear. | 2016 | 27538518 |
| preliminary results on the control of aedes spp. in a remote guatemalan community vulnerable to dengue, chikungunya and zika virus: community participation and use of low-cost ecological ovillantas for mosquito control. | objective: to study the effectiveness of an integrated intervention of health worker training, a low-cost ecological mosquito ovitrap, and community engagement on aedes spp. mosquito control over 10 months in 2015 in an urban remote community in guatemala at risk of dengue, chikungunya and zika virus transmission. methods: we implemented a three-component integrated intervention consisting of: web-based training of local health personnel in vector control, cluster-randomized assignment of an eco ... | 2016 | 28105304 |
| genetic variations in bionomics of culex quinquefasciatus (diptera: culicidae) mosquito population in minna, north central nigeria. | the need to have an improved knowledge on the bioecology of culex quinquefasciatus, a prerequisite in the development of cost-effective control strategies, has informed the present preliminary investigation to put in better perspective variations that exist in the egg rafts of the species. freshly laid egg rafts were collected and incubated at ambient temperature in well-labeled plastic trays. the results showed overall inconsistency in all indices monitored for the egg rafts. generally, survivo ... | 2016 | 27013900 |
| gravid anopheles gambiae sensu stricto avoid ovipositing in bermuda grass hay infusion and it's volatiles in two choice egg-count bioassays. | a number of mosquito species in the culex and aedes genera prefer to lay eggs in bermuda grass (cynodon dactylon) hay infusions compared to water alone. these mosquitoes are attracted to volatile compounds from the hay infusions making the infusions effective baits in gravid traps used for monitoring vectors of arboviral and filarial pathogens. since bermuda grass is abundant and widespread, it is plausible to explore infusions made from it as a potential low cost bait for outdoor monitoring of ... | 2016 | 27177033 |
| global risk model for vector-borne transmission of zika virus reveals the role of el niño 2015. | zika, a mosquito-borne viral disease that emerged in south america in 2015, was declared a public health emergency of international concern by the who in february of 2016. we developed a climate-driven r0 mathematical model for the transmission risk of zika virus (zikv) that explicitly includes two key mosquito vector species: aedes aegypti and aedes albopictus the model was parameterized and calibrated using the most up to date information from the available literature. it was then driven by ob ... | 2016 | 27994145 |
| deep sequencing-based transcriptome analysis reveals the regulatory mechanism of bemisia tabaci (hemiptera: aleyrodidae) nymph parasitized by encarsia sophia (hymenoptera: aphelinidae). | the whitefly bemisia tabaci is a genetically diverse complex with multiple cryptic species, and some are the most destructive invasive pests of many ornamentals and crops worldwide. encarsia sophia is an autoparasitoid wasp that demonstrated high efficiency as bio-control agent of whiteflies. however, the immune mechanism of b. tabaci parasitization by e. sophia is unknown. in order to investigate immune response of b. tabaci to e. sophia parasitization, the transcriptome of e. sophia parasitize ... | 2016 | 27332546 |
| functional analysis of orco and odorant receptors in odor recognition in aedes albopictus. | aedes albopictus is a globally invasive mosquito and a major vector of arboviruses, including dengue, zika and chikungunya. olfactory-related behaviors, particularly host-seeking, offer opportunities to disrupt the disease-transmission process. a better understanding of odorant receptors (ors) may assist in explaining host selection and location, and contribute to novel strategy of vector control. | 2016 | 27350348 |
| population genetic structure and potential incursion pathways of the bluetongue virus vector culicoides brevitarsis (diptera: ceratopogonidae) in australia. | culicoides brevitarsis is a vector of the bluetongue virus (btv), which infects sheep and cattle. it is an invasive species in australia with an assumed asian/south east asian origin. using one mitochondrial marker (i.e., part of the cytochrome oxidase subunit i gene) and six nuclear markers, we inferred population genetic structure and possible incursion pathways for australian c. brevitarsis. nine mitochondrial haplotypes, with low nucleotide sequence diversity (0.0-0.7%) among these, were ide ... | 2016 | 26771743 |
| application of copper-based ovitraps in local houses in west sumatra, indonesia: a field test of a simple and affordable larvicide for mosquito control. | the application of oviposition traps (ovitraps) is one of the currently available rational methods used in mosquito control campaigns because it eliminates the larval stage. however, the use of current larvicides is hampered by their cost and applicability. therefore, a more economical and practical alternative is urgently needed. we previously reported that copper in liquid form is a promising candidate due to its potent larvicide properties in a laboratory setting, affordability, and availabil ... | 2016 | 27433130 |
| artisanal extraction and traditional knowledge associated with medicinal use of crabwood oil (carapa guianensis aublet.) in a peri-urban várzea environment in the amazon estuary. | várzea forests of the amazon estuary contain species of importance to riverine communities. for example, the oil extracted from the seeds of crabwood trees is traditionally used to combat various illnesses and as such artisanal extraction processes have been maintained. the objectives of this study were to (1) describe the process involved in artisanal extraction of crabwood oil in the fazendinha protected area, in the state of amapá; (2) characterise the processes of knowledge transfer associat ... | 2016 | 27478479 |
| sarcoptes scabiei: genomics to proteomics to biology. | the common scabies mite, sarcoptes scabiei is a cosmopolitan parasite of humans and other mammals. an annotated genome of sarcoptes scabiei var. canis has been deposited in the national center for biotechnology information (ncbi) and vectorbase and a proteomic analysis of proteins in extracts of mite bodies and eggs from this strain has been reported. here we mined the data to identify predicted proteins that are known to be involved in specific biological processes in other animals. | 2016 | 27371026 |
| in vitro effect of seven essential oils on the reproduction of the cattle tick rhipicephalus microplus. | the acaricidal effect of seven essential oils was examined in vitro against the cattle tick (rhipicephalus microplus). engorged female ticks were manually collected in farms of southern brazil and placed into petri dishes (n = 10) in order to test the following oils: juniper (juniperus communis), palmarosa (cymbopogon martinii), cedar (cedrus atlantica), lemon grass (cymbopogon citratus), ginger (zingiber officinale), geranium (pelargonium graveolens) and bergamot (citrus aurantium var bergamia) ... | 2016 | 27857849 |
| acquisition of exogenous haem is essential for tick reproduction. | haem and iron homeostasis in most eukaryotic cells is based on a balanced flux between haem biosynthesis and haem oxygenase-mediated degradation. unlike most eukaryotes, ticks possess an incomplete haem biosynthetic pathway and, together with other (non-haematophagous) mites, lack a gene encoding haem oxygenase. we demonstrated, by membrane feeding, that ticks do not acquire bioavailable iron from haemoglobin-derived haem. however, ticks require dietary haemoglobin as an exogenous source of haem ... | 2016 | 26949258 |
| mevalonate-farnesal biosynthesis in ticks: comparative synganglion transcriptomics and a new perspective. | juvenile hormone (jh) controls the growth, development, metamorphosis, and reproduction of insects. for many years, the general assumption has been that jh regulates tick and other acarine development and reproduction the same as in insects. although researchers have not been able to find the common insect jhs in hard and soft tick species and jh applications appear to have no effect on tick development, it is difficult to prove the negative or to determine whether precursors to jh are made in t ... | 2016 | 26959814 |
| effect of the saliva from different triatomine species on the biology and immunity of tlr-4 ligand and trypanosoma cruzi-stimulated dendritic cells. | triatomines are blood-sucking vectors of trypanosoma cruzi, the causative agent of chagas disease. during feeding, triatomines surpass the skin host response through biomolecules present in their saliva. dendritic cells (dcs) play a crucial role in the induction of the protection to aggressive agents, including blood-sucking arthropods. here, we evaluated if salivary components of triatomines from different genera evade the host immunity by modulating the biology and the function of lps- or t. c ... | 2016 | 27938380 |
| the genome of the crustacean parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion. | the amphipod crustacean parhyale hawaiensis is a blossoming model system for studies of developmental mechanisms and more recently regeneration. we have sequenced the genome allowing annotation of all key signaling pathways, transcription factors, and non-coding rnas that will enhance ongoing functional studies. parhyale is a member of the malacostraca clade, which includes crustacean food crop species. we analysed the immunity related genes of parhyale as an important comparative system for the ... | 2016 | 27849518 |
| a crossover study to evaluate the diversion of malaria vectors in a community with incomplete coverage of spatial repellents in the kilombero valley, tanzania. | malaria elimination is unlikely to occur if vector control efforts focus entirely on transmission occurring indoors without addressing vectors that bite outdoors and outside sleeping hours. additional control tools such as spatial repellents may provide the personal protection required to fill this gap. however, since repellents do not kill mosquitoes it is unclear if vectors will be diverted from households that use spatial repellents to those that do not. | 2016 | 27527601 |
| rapid and high throughput molecular identification of diverse mosquito species by high resolution melting analysis. | mosquitoes are a diverse group of invertebrates, with members that are among the most important vectors of diseases. the correct identification of mosquitoes is paramount to the control of the diseases that they transmit. however, morphological techniques depend on the quality of the specimen and often unavailable taxonomic expertise, which may still not be able to distinguish mosquitoes among species complexes (sibling and cryptic species). high resolution melting (hrm) analyses, a closed-tube, ... | 2016 | 27703667 |
| evaluation of the larvicidal efficacy of five indigenous weeds against an indian strain of dengue vector, aedes aegypti l. (diptera: culicidae). | background and objectives. aedes aegypti, dengue fever mosquito, is primarily associated with the transmission of dengue and chikungunya in tropical and subtropical regions of the world. the present investigations were carried out to assess the larvicidal efficiency of five indigenous weeds against ae. aegypti. methods. the 1,000 ppm hexane and ethanol extracts prepared from the leaves and stem of five plants (achyranthes aspera, cassia occidentalis, catharanthus roseus, lantana camara, and xant ... | 2016 | 26941996 |
| horizontally transferred genetic elements in the tsetse fly genome: an alignment-free clustering approach using batch learning self-organising map (blsom). | tsetse flies (glossina spp.) are the primary vectors of trypanosomes, which can cause human and animal african trypanosomiasis in sub-saharan african countries. the objective of this study was to explore the genome of glossina morsitans morsitans for evidence of horizontal gene transfer (hgt) from microorganisms. we employed an alignment-free clustering method, that is, batch learning self-organising map (blsom), in which sequence fragments are clustered based on the similarity of oligonucleotid ... | 2016 | 28074180 |
| bioinformatic characterization of mosquito viromes within the eastern united states and puerto rico: discovery of novel viruses. | mosquitoes are efficient, militarily relevant vectors of infectious disease pathogens, including many rna viruses. the vast majority of all viruses are thought to be undiscovered. accordingly, recent studies have shown that viruses discovered in insects are very divergent from known pathogens and that many of them lack appropriate reference sequences in the public databases. given that the majority of viruses are likely still undiscovered, environ mental sampling stands to provide much needed re ... | 2016 | 27346944 |
| seasonal differences in density but similar competitive impact of aedes albopictus (skuse) on aedes aegypti (l.) in rio de janeiro, brazil. | previous studies have shown that the negative effects of density of ae. albopictus on ae. aegypti exceed those of ae. aegypti on ae. albopictus for population growth, adult size, survivorship, and developmental rate. this competitive superiority has been invoked to explain the displacement of ae. aegypti by ae. albopictus in the southeastern usa. in brazil, these species coexist in many vegetated suburban and rural areas. we investigated a related, but less-well-studied question: do effects of a ... | 2016 | 27322537 |
| species-specific escape of plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites. | malaria is transmitted when an infected mosquito delivers plasmodium sporozoites into a vertebrate host. there are many species of plasmodium and, in general, the infection is host-specific. for example, plasmodium gallinaceum is an avian parasite, while plasmodium berghei infects mice. these two parasites have been extensively used as experimental models of malaria transmission. plasmodium falciparum and plasmodium vivax are the most important agents of human malaria, a life-threatening disease ... | 2016 | 27480269 |
| expression patterns, mutation detection and rna interference of rhopalosiphum padi voltage-gated sodium channel genes. | the voltage-gated sodium channel (vgsc) is the target of sodium-channel-blocking insecticides. traditionally, animals were thought to have only one vgsc gene comprising a α-subunit with four homologous domains (di-div). the present study showed that rhopalosiphum padi, an economically important crop pest, owned a unique heterodimeric vgsc (h1 and h2 subunits) encoded by two genes (rpvgsc1 and rpvgsc2), which is unusual in insects and other animals. the open reading frame (orf) of rpvgsc1 consist ... | 2016 | 27439594 |