Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| weight of evidence evaluation of a network of adverse outcome pathways linking activation of the nicotinic acetylcholine receptor in honey bees to colony death. | ongoing honey bee (apis mellifera) colony losses are of significant international concern because of the essential role these insects play in pollinating crops. both chemical and non-chemical stressors have been implicated as possible contributors to colony failure; however, the potential role(s) of commonly-used neonicotinoid insecticides has emerged as particularly concerning. neonicotinoids act on the nicotinic acetylcholine receptors (nachrs) in the central nervous system to eliminate pest i ... | 2017 | 28126277 |
| mblk-1 transcription factor family: its roles in various animals and regulation by nol4 splice variants in mammals. | transcription factors play critical roles in regulation of neural development and functions. a transcription factor mblk-1 was previously reported from a screen for factors possibly important for the higher brain functions of the honeybee. this review first summarizes how mblk-1 was identified, and then provides an overview of the studies of mblk-1 and their homologs. mblk-1 family proteins are found broadly in animals and are shown to affect transcription activities. studies have revealed that ... | 2017 | 28125049 |
| a lévy-flight diffusion model to predict transgenic pollen dispersal. | the containment of genetically modified (gm) pollen is an issue of significant concern for many countries. for crops that are bee-pollinated, model predictions of outcrossing rates depend on the movement hypothesis used for the pollinators. previous work studying pollen spread by honeybees, the most important pollinator worldwide, was based on the assumption that honeybee movement can be well approximated by brownian motion. a number of recent studies, however, suggest that pollinating insects s ... | 2017 | 28123097 |
| blockade of nmda receptors decreased spinal microglia activation in bee venom induced acute inflammatory pain in rats. | microglial cells in spinal dorsal horn can be activated by nociceptive stimuli and the activated microglial cells release various cytokines enhancing the nociceptive transmission. however, the mechanisms underlying the activation of spinal microglia during nociceptive stimuli have not been well understood. in order to define the role of nmda receptors in the activation of spinal microglia during nociceptive stimuli, the present study was undertaken to investigate the effect of blockade of nmda r ... | 2017 | 28120640 |
| erratum to: inhibitory effects of bee venom and its components against viruses in vitro and in vivo. | 2017 | 28120196 | |
| risk assessment of various insecticides used for management of asian citrus psyllid, diaphorina citri in florida citrus, against honey bee, apis mellifera. | the asian citrus psyllid, diaphorina citri kuwayama (hemiptera: liviidae), is a major pest of citrus trees worldwide. a wide variety of insecticides are used to manage d. citri populations within citrus groves in florida. however, in areas shared by citrus growers and beekeepers the use of insecticides may increase the risks of apis mellifera l. (hymenoptera: apidae) loss and contaminated honey. the objective of this research was to determine the environmental toxicity of insecticides, spanning ... | 2017 | 28116643 |
| performance of honey bee colonies under a long-lasting dietary exposure to sublethal concentrations of the neonicotinoid insecticide thiacloprid. | substantial honey bee colony losses have occurred periodically in the last decades. the drivers for these losses are not fully understood. the influence of pests and pathogens are beyond dispute, but in addition, chronic exposure to sublethal concentrations of pesticides has been suggested to affect the performance of honey bee colonies. this study aims to elucidate the potential effects of a chronic exposure to sublethal concentrations (one realistic worst-case concentration) of the neonicotino ... | 2017 | 28168846 |
| learning, gustatory responsiveness and tyramine differences across nurse and forager honeybees. | honeybees are well known for their complex division of labor. each bee sequentially performs a series of social tasks during its life. the changes in social task performance are linked to gross differences in behavior and physiology. we here tested whether honeybees performing different social tasks (nursing vs. foraging) would differ in their gustatory responsiveness and associative learning behavior in addition to their daily tasks in the colony. further, we investigated the role of the biogen ... | 2017 | 28167800 |
| the complex demographic history and evolutionary origin of the western honey bee, apis mellifera. | 2017 | 28164223 | |
| an experiment on the impact of a neonicotinoid pesticide on honeybees: the value of a formal analysis of the data. | we assess the analysis of the data resulting from a field experiment conducted by pilling et al. (plos one. doi: 10.1371/journal.pone.0077193, 5) on the potential effects of thiamethoxam on honeybees. the experiment had low levels of replication, so pilling et al. concluded that formal statistical analysis would be misleading. this would be true if such an analysis merely comprised tests of statistical significance and if the investigators concluded that lack of significance meant little or no e ... | 2017 | 28163992 |
| authors response on schick et al. 2017 "an experiment of the impact of a neonicotinoid pesticide on honey bees; the value of a formal analysis of the data". environ sci eur (2017). | whilst a formal statistical analysis of any experimental data is always preferable in principle, in the case of pilling et al. (plos one 8:e77193, 2013), it is hard to see how the results of any formal analysis-including those provided by schick et al.-could be considered reliable. regardless of the issue of statistical analysis, there was a wealth of valuable and novel biological and chemical residue data generated under field conditions of use in pilling et al., which when taken into considera ... | 2017 | 28163990 |
| foraging in an unsteady world: bumblebee flight performance in field-realistic turbulence. | natural environments are characterized by variable wind that can pose significant challenges for flying animals and robots. however, our understanding of the flow conditions that animals experience outdoors and how these impact flight performance remains limited. here, we combine laboratory and field experiments to characterize wind conditions encountered by foraging bumblebees in outdoor environments and test the effects of these conditions on flight. we used radio-frequency tags to track forag ... | 2017 | 28163878 |
| proteomic and metabolomic analysis reveals rapid and extensive nicotine detoxification ability in honey bee larvae. | despite potential links between pesticides and bee declines, toxicology information on honey bee larvae (apis mellifera) is scarce and detoxification mechanisms in this development stage are virtually unknown. larvae are exposed to natural and synthetic toxins present in pollen and nectar through consumption of brood food. due to the characteristic intensive brood care displayed by honey bees, which includes progressive feeding throughout larval development, it is generally assumed that larvae r ... | 2017 | 28161469 |
| insect bio-inspired neural network provides new evidence on how simple feature detectors can enable complex visual generalization and stimulus location invariance in the miniature brain of honeybees. | the ability to generalize over naturally occurring variation in cues indicating food or predation risk is highly useful for efficient decision-making in many animals. honeybees have remarkable visual cognitive abilities, allowing them to classify visual patterns by common features despite having a relatively miniature brain. here we ask the question whether generalization requires complex visual recognition or whether it can also be achieved with relatively simple neuronal mechanisms. we produce ... | 2017 | 28158189 |
| differential gene expression associated with honey bee grooming behavior in response to varroa mites. | honey bee (apis mellifera) grooming behavior is an important mechanism of resistance against the parasitic mite varroa destructor. this research was conducted to study associations between grooming behavior and the expression of selected immune, neural, detoxification, developmental and health-related genes. individual bees tested in a laboratory assay for various levels of grooming behavior in response to v. destructor were also analyzed for gene expression. intense groomers (ig) were most effi ... | 2017 | 28154949 |
| sexual response of male drosophila to honey bee queen mandibular pheromone: implications for genetic studies of social insects. | honey bees secrete a queen mandibular pheromone that renders workers reproductively altruistic and drones sexually attentive. this sex-specific function of qmp may have evolved from a sexually dimorphic signaling mechanism derived from pre-social ancestors. if so, there is potential for pre-social insects to respond to qmp, and in a manner that is comparable to its normal effect on workers and drones. remarkably, qmp applied to female drosophila does induce worker-like qualities [camiletti et al ... | 2017 | 28150219 |
| reproductive biology and pollination ecology of triplaris gardneriana (polygonaceae): a case of ambophily in the brazilian chaco. | triplaris gardneriana (polygonaceae) is a dioecious pioneer tree reported as insect-pollinated, despite possessing traits related to anemophily. here, we analyse the possible roles of insects and wind on the pollination of this species to establish whether the species is ambophilous. we carried out observations of floral biology, as well as on the frequency and behaviour of pollinators visiting flowers in a population of t. gardneriana in the chaco vegetation of brazil. we conducted experimental ... | 2017 | 28145619 |
| honeybee locomotion is impaired by am-cav3 low voltage-activated ca(2+) channel antagonist. | voltage-gated ca(2+) channels are key transducers of cellular excitability and participate in several crucial physiological responses. in vertebrates, 10 ca(2+) channel genes, grouped in 3 families (cav1, cav2 and cav3), have been described and characterized. insects possess only one member of each family. these genes have been isolated in a limited number of species and very few have been characterized although, in addition to their crucial role, they may represent a collateral target for neuro ... | 2017 | 28145504 |
| blown by the wind: the ecology of male courtship display behavior in orchid bees. | many insects rely on chemical signals to transmit precise information on the location, identity, and quality of potential mates. chemical signals are often broadcasted at sites with physical properties that maximize signal propagation and signal transmission. male neotropical orchid bees (euglossini) perch and display on vertical branches and tree trunks in the forest to expose volatile blends (perfumes) that they previously collected from their environment. previous studies have shown that the ... | 2017 | 28144949 |
| midgut bacterial communities in the giant asian honeybee (apis dorsata) across 4 developmental stages: a comparative study. | bacterial communities are known to play important roles during the developmental stages of insects, but current knowledge of bacteria associated with the midgut of apis dorsata, the giant asian honeybee, is limited. using polymerase chain reaction-denaturing gradient gel electrophoresis analysis (pcr-dgge) and 16s rrna sequencing, the aim of this study was to determine the dynamics of bacterial community structure across four a. dorsata life stages in different geographical locations. the result ... | 2017 | 26299408 |
| agricultural landscape and pesticide effects on honey bee (hymenoptera: apidae) biological traits. | sixteen honey bee (apis mellifera l.) colonies were placed in four different agricultural landscapes to study the effects of agricultural landscape and exposure to pesticides on honey bee health. colonies were located in three different agricultural areas with varying levels of agricultural intensity (ag areas) and one nonagricultural area (nag area). colonies were monitored for their performance and productivity for one year by measuring colony weight changes, brood production, and colony therm ... | 2017 | 28398581 |
| total and honeybee venom-specific serum igg4 and ige in beekeepers. | 2017 | 28398208 | |
| the geometric framework for nutrition reveals interactions between protein and carbohydrate during larval growth in honey bees. | in holometabolous insects, larval nutrition affects adult body size, a life history trait with a profound influence on performance and fitness. individual nutritional components of larval diets are often complex and may interact with one another, necessitating the use of a geometric framework for elucidating nutritional effects. in the honey bee, apis mellifera, nurse bees provision food to developing larvae, directly moderating growth rates and caste development. however, the eusocial nature of ... | 2017 | 28396492 |
| investigation of span-chordwise bending anisotropy of honeybee forewings. | in this study, the spanwise and chordwise bending stiffness ei of honeybee forewings were measured by a cantilevered bending test. the interesting test results indicate that the spanwise ei of the forewing is two orders of magnitude larger than the chordwise ei three structural aspects result in this span-chordwise bending anisotropy: the distribution of resilin patches, the corrugation along the span and the leading edge vein of the venation. it was found that flexion lines formed by resilin pa ... | 2017 | 28396486 |
| oldest varroa tolerant honey bee population provides insight into the origins of the global decline of honey bees. | the ecto-parasitic mite varroa destructor has transformed the previously inconsequential deformed wing virus (dwv) into the most important honey bee viral pathogen responsible for the death of millions of colonies worldwide. naturally, dwv persists as a low level covert infection transmitted between nest-mates. it has long been speculated that varroa via immunosuppression of the bees, activate a covert infection into an overt one. here we show that despite varroa feeding on a population of 20-40 ... | 2017 | 28393875 |
| replication of honey bee-associated rna viruses across multiple bee species in apple orchards of georgia, germany and kyrgyzstan. | the essential ecosystem service of pollination is provided largely by insects, which are considered threatened by diverse biotic and abiotic global change pressures. rna viruses are one such pressure, and have risen in prominence as a major threat for honey bees (apis mellifera) and global apiculture, as well as a risk factor for other bee species through pathogen spill-over between managed honey bees and sympatric wild pollinator communities. yet despite their potential role in global bee decli ... | 2017 | 28392285 |
| the impact of gc bias on phylogenetic accuracy using targeted enrichment phylogenomic data. | the field of sequence based phylogenetic analyses is currently being transformed by novel hybrid-based targeted enrichment methods, such as the use of ultraconserved elements (uces). rather than analyzing relationships among organisms using a small number of genes, these methods now allow us to evaluate relationships with many hundreds to thousands of individual gene loci. however, the inclusion of thousands of loci does not necessarily overcome the long-standing challenge of incongruence among ... | 2017 | 28390323 |
| effects of bacillus thuringiensis strains virulent to varroa destructor on larvae and adults of apis mellifera. | the sublethal effects of two strains of bacillus thuringiensis, which were virulent in vitro to varroa destructor, were measured on apis mellifera. the effects of five concentrations of total protein (1, 5, 25, 50 and 100μg/ml) from the ea3 and ea26.1 strains on larval and adult honey bees were evaluated for two and seven days under laboratory conditions. based on the concentrations evaluated, total protein from the two strains did not affect the development of larvae, the syrup consumption, loc ... | 2017 | 28388479 |
| odorant cues linked to social immunity induce lateralized antenna stimulation in honey bees (apis mellifera l.). | hygienic behaviour (hb) is a social immunity trait in honey bees (apis mellifera l.) whereby workers detect, uncap and remove unhealthy brood, improving disease resistance in the colony. this is clearly economically valuable; however, the molecular mechanism behind it is not well understood. the freeze-killed brood (fkb) assay is the conventional method of hb selection, so we compared odour profiles of fkb and live brood to find candidate hb-inducing odours. surprisingly, we found that significa ... | 2017 | 28387332 |
| diploid male production results in queen death in the stingless bee scaptotrigona depilis. | as in most hymenoptera, the eusocial stingless bees (meliponini) have a complementary sex determination (csd) system. when a queen makes a "matched mating" with a male that shares a csd allele with her, half of their diploid offspring are diploid males rather than females. matched mating imposes a cost, since diploid male production reduces the colony workforce. hence, adaptations preventing the occurrence or attenuating its effects are likely to arise. here we provide clear evidence that in the ... | 2017 | 28386801 |
| chemical ecology of stingless bees. | stingless bees (hymenoptera, apidae: meliponini) represent a highly diverse group of social bees confined to the world's tropics and subtropics. they show a striking diversity of structural and behavioral adaptations and are important pollinators of tropical plants. despite their diversity and functional importance, their ecology, and especially chemical ecology, has received relatively little attention, particularly compared to their relative the honeybee, apis mellifera. here, i review various ... | 2017 | 28386800 |
| dynamic population artificial bee colony algorithm for multi-objective optimal power flow. | this paper proposes a novel artificial bee colony algorithm with dynamic population (abc-dp), which synergizes the idea of extended life-cycle evolving model to balance the exploration and exploitation tradeoff. the proposed abc-dp is a more bee-colony-realistic model that the bee can reproduce and die dynamically throughout the foraging process and population size varies as the algorithm runs. abc-dp is then used for solving the optimal power flow (opf) problem in power systems that considers t ... | 2017 | 28386199 |
| a novel comprehensive learning artificial bee colony optimizer for dynamic optimization biological problems. | there are many dynamic optimization problems in the real world, whose convergence and searching ability is cautiously desired, obviously different from static optimization cases. this requires an optimization algorithm adaptively seek the changing optima over dynamic environments, instead of only finding the global optimal solution in the static environment. this paper proposes a novel comprehensive learning artificial bee colony optimizer (clabc) for optimization in dynamic environments problem ... | 2017 | 28386198 |
| [ocular complications after honeybee sting therapy for a pterygium]. | 2017 | 28385271 | |
| role of human action in the spread of honey bee (hymenoptera: apidae) pathogens. | the increased annual losses in european honey bee (apis mellifera) colonies in north america and some other countries is usually attributed to a range of factors including pathogens, poor nutrition, and insecticides. in this essay, i will argue that the global trade in honey bees and migratory beekeeping practices within countries has enabled pathogens to spread quickly. beekeepers' management strategies have also contributed to the spread of pathogens as well as the development of resistance to ... | 2017 | 28383702 |
| provenance establishment of stingless bee honey using multi-element analysis in combination with chemometrics techniques. | as consumption of stingless bee honey has been gaining popularity in many countries including malaysia, ability to identify accurately its geographical origin proves pertinent for investigating fraudulent activities for consumer protection. because a chemical signature can be location-specific, multi-element distribution patterns may prove useful for provenancing such product. using the inductively coupled-plasma optical emission spectrometer as well as principal component analysis (pca) and lin ... | 2017 | 28383137 |
| visual acuity of the honey bee retina and the limits for feature detection. | visual abilities of the honey bee have been studied for more than 100 years, recently revealing unexpectedly sophisticated cognitive skills rivalling those of vertebrates. however, the physiological limits of the honey bee eye have been largely unaddressed and only studied in an unnatural, dark state. using a bright display and intracellular recordings, we here systematically investigated the angular sensitivity across the light adapted eye of honey bee foragers. angular sensitivity is a measure ... | 2017 | 28383025 |
| brazilian green propolis promotes weight loss and reduces fat accumulation in c57bl/6 mice fed a high-fat diet. | propolis is a bee product with various biological properties. c57bl/6 mice were fed a high-fat diet and treated with propolis for 14 weeks. body weight in mice treated with 2% propolis was less than that in control mice from 3 weeks after the start of treatment until 14 weeks except for the 7th week. mice treated with propolis showed significantly lower epididymal fat weight and subcutaneous fat weight. infiltration of epididymal fat by macrophages and t cells was reduced in the propolis group. ... | 2017 | 28381793 |
| abscisic acid enhances cold tolerance in honeybee larvae. | the natural composition of nutrients present in food is a key factor determining the immune function and stress responses in the honeybee (apis mellifera). we previously demonstrated that a supplement of abscisic acid (aba), a natural component of nectar, pollen, and honey, increases honeybee colony survival overwinter. here we further explored the role of aba in in vitro-reared larvae exposed to low temperatures. four-day-old larvae (l4) exposed to 25°c for 3 days showed lower survival rates an ... | 2017 | 28381619 |
| bee safe, a skill-building intervention to enhance cam health literacy: lessons learned. | the purpose is to describe a feasibility study of a skill-building intervention to enhance health literacy about complementary and alternative (cam) therapies among older rural adults and share lessons learned. a study was designed to examine the feasibility of an intervention to enhance cam health literacy. the theme was "bee safe" for be a wise user of cam, safety, amount, from where, and effect. modules were presented face to face and by webinar with older adults at a senior center in one sma ... | 2017 | 28381096 |
| long-term follow-up of children after venom immunotherapy: low adherence to anaphylaxis guidelines. | data on the long-term outcome of children after specific venom immunotherapy (vit) are limited. therefore, we assessed sting recurrence and anaphylaxis relapse rates as well as adherence to anaphylaxis guidelines with regard to the availability of emergency equipment and education status. | 2017 | 28380475 |
| medically-graded honey supplementation formula to preterm infants as a prebiotic: a randomized controlled trial. | to assess the effect of medically-graded enteral honey supplementation on the intestinal microbiota, immune response, and somatic growth of preterm infants. | 2017 | 28379925 |
| does passive sampling accurately reflect the bee (apoidea: anthophila) communities pollinating apple and sour cherry orchards? | during bloom of spring orchard crops, bees are the primary providers of pollination service. monitoring these insects for research projects is often done by timed observations or by direct aerial netting, but there has been increasing interest in blue vane traps as an efficient passive approach to collecting bees. over multiple spring seasons in michigan and pennsylvania, orchards were monitored for wild bees using timed netting from crop flowers and blue vane traps. this revealed a distinctly d ... | 2017 | 28379550 |
| wildflower plantings do not compete with neighboring almond orchards for pollinator visits. | the engineering of flowering agricultural field borders has emerged as a research and policy priority to mitigate threats to pollinators. studies have, however, rarely addressed the potential that flowering field borders might compete with neighboring crops for pollinator visits if they both are in bloom at the same time, despite this being a concern expressed by growers. we evaluated how wildflower plantings added to orchard borders in a large (512 ha) commercial almond orchard affected honey b ... | 2017 | 28379320 |
| genome-wide analysis of admixture and adaptation in the africanized honeybee. | genetic exchange by hybridization or admixture can make an important contribution to evolution, and introgression of favourable alleles can facilitate adaptation to new environments. a small number of honeybees (apis mellifera) with african ancestry were introduced to brazil ~60 years ago, which dispersed and hybridized with existing managed populations of european origin, quickly spreading across much of the americas in an example of a massive biological invasion. here we analyse whole genome s ... | 2017 | 28378497 |
| antioxidant, cytotoxic, and toxic activities of propolis from two native bees in brazil: scaptotrigona depilis and melipona quadrifasciata anthidioides. | propolis is a natural mixture of compounds produced by various bee species, including stingless bees. this compound has been shown to exhibit antioxidant, antiproliferative, and antitumor activities. the present study aimed to determine the chemical constituents as well as the antioxidant, cytotoxic, and toxic activities of ethanol extracts of propolis obtained from the stingless bees scaptotrigona depilis and melipona quadrifasciata anthidioides, which are found in brazil. phytosterols, terpene ... | 2017 | 28377794 |
| infections of virulent and avirulent viruses differentially influenced the expression of dicer-1, ago-1, and micrornas in bombus terrestris. | the microrna (mirna) pathway is well established to be involved in host-pathogen interactions. as key insect pollinators, bees are suffering from widely spreading viruses, especially honeybees and bumblebees. in order to better understand bee-virus interaction, we comparatively analyzed the involvement of the bumblebee mirna pathway upon infection by two different viruses. in our setup, an avirulent infection is induced by slow bee paralysis virus (sbpv) and a virulent infection is induced by is ... | 2017 | 28374846 |
| in search of evidence for the experience of pain in honeybees: a self-administration study. | despite their common use as model organisms in scientific experiments, pain and suffering in insects remains controversial and poorly understood. here we explore potential pain experience in honeybees (apis mellifera) by testing the self-administration of an analgesic drug. foragers were subjected to two different types of injuries: (i) a clip that applied continuous pressure to one leg and (ii) amputation of one tarsus. the bees were given a choice between two feeders, one offering pure sucrose ... | 2017 | 28374827 |
| three years of banning neonicotinoid insecticides based on sub-lethal effects: can we expect to see effects on bees? | the 2013 eu ban of three neonicotinoids used in seed coating of pollinator attractive crops was put in place because of concern about declining wild pollinator populations and numbers of honeybee colonies. it was also concluded that there is an urgent need of good field data to fill knowledge gaps. in the meantime such data have been generated. based on recent literature we question the existence of recent pollinator declines and their possible link with the use of neonicotinoids. because of tem ... | 2017 | 28374565 |
| free-flying honeybees extrapolate relational size rules to sort successively visited artificial flowers in a realistic foraging situation. | learning and applying relational concepts to solve novel tasks is considered an indicator of cognitive-like ability. it requires the abstraction of relational concepts to different objects independent to the physical nature of the individual objects. recent research has revealed the honeybee's ability to rapidly learn and manipulate relations between visual stimuli such as 'same/different', 'above/below', or 'larger/smaller' despite having a miniature-sized brain. while honeybees can solve probl ... | 2017 | 28374206 |
| a novel interval type-2 fractional order fuzzy pid controller: design, performance evaluation, and its optimal time domain tuning. | in this paper, a novel concept of an interval type-2 fractional order fuzzy pid (it2fo-fpid) controller, which requires fractional order integrator and fractional order differentiator, is proposed. the incorporation of takagi-sugeno-kang (tsk) type interval type-2 fuzzy logic controller (it2flc) with fractional controller of pid-type is investigated for time response measure due to both unit step response and unit load disturbance. the resulting it2fo-fpid controller is examined on different del ... | 2017 | 28372800 |
| longevity extension of worker honey bees (apis mellifera) by royal jelly: optimal dose and active ingredient. | in the western honey bee, apis mellifera, queens and workers have different longevity although they share the same genome. queens consume royal jelly (rj) as the main food throughout their life, including as adults, but workers only eat worker jelly when they are larvae less than 3 days old. in order to explore the effect of rj and the components affecting longevity of worker honey bees, we first determined the optimal dose for prolonging longevity of workers as 4% rj in 50% sucrose solution, an ... | 2017 | 28367370 |
| the effect of nest box distribution on sustainable propagation of osmia lignaria (hymenoptera: megachilidae) in commercial tart cherry orchards. | the blue orchard bee, osmia lignaria (say), is a solitary bee that is an excellent pollinator of tree fruit orchards. due to the annual rising costs of honey bee hive rentals, many orchardists are eager to develop management tools and practices to support o. lignaria as an alternative pollinator. establishing o. lignaria pollination as a sustainable industry requires careful consideration of both bee and orchard management. here, we test the effect of artificial nest box distribution on in-orcha ... | 2017 | 28365763 |
| caffeic acid phenethyl ester protects against glucocorticoid-induced osteoporosis in vivo: impact on oxidative stress and rankl/opg signals. | glucocorticoid-induced osteoporosis (gio) is one of the most common causes of secondary osteoporosis. given that glucocorticoids are considered as a main component of the treatment protocols for a variety of inflammation and immune-mediated diseases besides its use as adjuvant to several chemotherapeutic agents, it is crucial to find ways to overcome this critical adverse effect. caffeic acid phenethyl ester (cape), which is a natural compound derived from honeybee propolis displayed promising a ... | 2017 | 28363435 |
| effect of major royal jelly proteins on spatial memory in aged rats: metabolomics analysis in urine. | royal jelly (rj) produced by worker honeybees is the sole food for the queen bee throughout her life as well as the larvae of worker bees for the first 3 days after hatching. supplementation of rj in the diet has been shown to increase spatial memory in rodents. however, the key constituents in rj responsible for improvement of cognitive function are unknown. our objective was to determine if the major royal jelly proteins (mrjps) extracted from rj can improve the spatial memory of aged rats. th ... | 2017 | 28362493 |
| micrornas associated with caste determination and differentiation in a primitively eusocial insect. | in eusocial hymenoptera (ants, bees and wasps), queen and worker adult castes typically arise via environmental influences. a fundamental challenge is to understand how a single genome can thereby produce alternative phenotypes. a powerful approach is to compare the molecular basis of caste determination and differentiation along the evolutionary trajectory between primitively and advanced eusocial species, which have, respectively, relatively undifferentiated and strongly differentiated adult c ... | 2017 | 28361900 |
| condition-dependent virulence of slow bee paralysis virus in bombus terrestris: are the impacts of honeybee viruses in wild pollinators underestimated? | slow bee paralysis virus (sbpv)-previously considered an obligate honeybee disease-is now known to be prevalent in bumblebee species. sbpv is highly virulent in honeybees in association with varroa mites, but has been considered relatively benign otherwise. however, condition-dependent pathogens can appear asymptomatic under good, resource abundant conditions, and negative impacts on host fitness may only become apparent when under stressful or resource-limited conditions. we tested whether sbpv ... | 2017 | 28361244 |
| common antibiotic hurts bee survival. | 2017 | 28360316 | |
| a case series of bee sting keratopathy with different outcomes in malaysia. | we report three patients with corneal bee sting at our tertiary care center in a three-year period starting from 2014 to 2016. all patients sustained a bee sting injury to the cornea. all patients received early preoperative topical antibiotics, topical cycloplegic and intensive topical steroids. however, the timing of the initial presentation, the duration, and the location of the retained stinger differed in each case leading to different postsurgical outcomes. | 2017 | 28357167 |
| melittin inhibits the invasion of mcf-7 cells by downregulating cd147 and mmp-9 expression. | tumor invasion and metastasis are the critical steps in determining the aggressive phenotype of human cancers. melittin, a major component of bee venom, has been reported to induce apoptosis in several cancer cells. however, the mechanisms of melittin involvement in cancer invasion and metastasis remain unclear. our previous study indicated that melittin inhibits cyclophilin a (cypa), a ubiquitously distributed peptidylprolyl cis-trans isomerase, in macrophage cells. in the present study, the tr ... | 2017 | 28356935 |
| the dynamic association between ovariole loss and sterility in adult honeybee workers. | in the social insects, ovary state (the presence or absence of mature oocytes) and ovary size (the number of ovarioles) are often used as proxies for the reproductive capacity of an individual worker. ovary size is assumed to be fixed post-eclosion whereas ovary state is demonstrably plastic post-eclosion. here, we show that in fact ovary size declines as honeybee workers age. this finding is robust across two honeybee species: apis mellifera and a. cerana the ovariole loss is likely to be due t ... | 2017 | 28356452 |
| biophysical characterization of the varroa destructor nav1 sodium channel and its affinity for τ-fluvalinate insecticide. | the decline of the western honeybee (apis mellifera) has been reported to be due to parasitism by varroa destructor mites and to colony collapse disorder in which these mites may be involved. in-hive chemicals such as τ-fluvalinate are being used to control vdestructor populations. this approach may lead to the chronic exposure of bees to this liposoluble chemical, which tends to accumulate in hives. we cloned a variant of the v. destructor sodium channel (vdnav1) and studied its biophysical cha ... | 2017 | 28356346 |
| drag reduction in a natural high-frequency swinging micro-articulation: mouthparts of the honey bee. | worker-bee mouthparts consist of the glossa, the galeae and the vestigial labial palp, and it is these structures that enable bees to feed themselves. the articulation joints, 60∼70 µm in diameter, are present on the tip of the labial palp and are covered with olfactory sensilla, allowing movements between the segments. using a specially designed high-speed camera system, we discovered that the articulation joint could swing in the nectar at a frequency of ∼50 hz, considerably higher than the us ... | 2017 | 28355472 |
| food consumption and food exchange of caged honey bees using a radioactive labelled sugar solution. | we measured the distribution of sugar solution within groups of caged honey bees (apis mellifera) under standard in vitro laboratory conditions using 14c polyethylene glycol as a radioactive marker to analyze ingestion by individual bees after group feeding. we studied the impact of different experimental setups by varying the number of bees, age of bees, origin of bees, duration of experiment, the amount of available diet, and the influence of the neurotoxic pesticide imidacloprid in the diet o ... | 2017 | 28355267 |
| melittin inhibits osteoclast formation through the downregulation of the rankl-rank signaling pathway and the inhibition of interleukin-1β in murine macrophages. | melittin is a major toxic component of bee venom (apis mellifera). it is not known whether melittin is involved in bone metabolism and osteoclastogenesis. the aim of this study was to determine the role of melittin in the regulation of osteoclastogenesis. in vitro osteoclastogenesis assays were performed using mouse raw 264.7 cells and bone marrow-derived macrophages (bmms) treated with receptor activator of nuclear factor-κb ligand (rankl) and macrophage colony-stimulating factor (m-csf). morph ... | 2017 | 28350111 |
| improvement of identification methods for honeybee specific lactic acid bacteria; future approaches. | honeybees face many parasites and pathogens and consequently rely on a diverse set of individual and group-level defenses to prevent disease. the crop microbiota of apis mellifera, composed of 13 lactic acid bacterial (lab) species within the genera lactobacillus and bifidobacterium, form a beneficial symbiotic relationship with each other and the honeybee to protect their niche and their host. possibly playing a vital role in honeybee health, it is important that these honeybee specific lactic ... | 2017 | 28346815 |
| six years of instand e. v. sige proficiency testing: an evaluation of in vitro allergy diagnostics. | even though allergies are an important health issue, wide manufacturer-dependent differences in the detected amounts of allergen-specific ige (sige) have repeatedly been found. these discrepancies hinder diagnostics and research into clinically significant cutoff points for life-threatening symptoms. | 2017 | 28344920 |
| direct interaction between caffeic acid phenethyl ester and human neutrophil elastase inhibits the growth and migration of panc-1 cells. | pancreatic ductal adenocarcinoma (pdac) is one of the most lethal malignant tumors of the digestive system, but the mechanisms of its development and progression are unclear. inflammation is thought to be fundamental to pancreatic cancer development and caffeic acid phenethyl ester (cape) is an active component of honey bee resin or propolis with anti-inflammatory and anticancer activities. we investigated the inhibitory effects of cape on cell growth and migration induced by human neutrophil el ... | 2017 | 28339071 |
| antioxidant and anti-tyrosinase activities of phenolic extracts from rape bee pollen and inhibitory melanogenesis by camp/mitf/tyr pathway in b16 mouse melanoma cells. | rape bee pollen possesses many nutritional and therapeutic properties because of its abundant nutrimental and bioactive components. in this study, free (fpe) and bound (bpe) phenolic extracts of rape bee pollen were obtained, phenolic and flavonoid contents were determined, and composition of phenolic acids was analyzed. in vitro antioxidant and anti-tyrosinase (tyr) activities of fpe and bpe were compared, and inhibitory melanogenesis of fpe was further evaluated. results showed fpe and bpe con ... | 2017 | 28337140 |
| erratum to: unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens. | 2017 | 28335723 | |
| pollinator identity and spatial isolation influence multiple paternity in an annual plant. | the occurrence and extent of multiple paternity is an important component of variation in plant mating dynamics. however, links between pollinator activity and multiple paternity are generally lacking, especially for plant species that attract functionally diverse floral visitors. in this study, we separated the influence of two functionally distinct floral visitors (hawkmoths and solitary bees) and characterized their impacts on multiple paternity in a self-incompatible, annual forb, oenothera ... | 2017 | 28334485 |
| a bio-economic case study of canadian honey bee (hymenoptera: apidae) colonies: marker-assisted selection (mas) in queen breeding affects beekeeper profits. | over the past decade in north america and europe, winter losses of honey bee (hymenoptera: apidae) colonies have increased dramatically. scientific consensus attributes these losses to multifactorial causes including altered parasite and pathogen profiles, lack of proper nutrition due to agricultural monocultures, exposure to pesticides, management, and weather. one method to reduce colony loss and increase productivity is through selective breeding of queens to produce disease-, pathogen-, and ... | 2017 | 28334400 |
| the synergistic effects of almond protection fungicides on honey bee (hymenoptera: apidae) forager survival. | the honey bee (apis mellifera l.) contributes ∼$17 billion annually to the united states economy, primarily by pollinating major agricultural crops including almond, which is completely dependent on honey bee pollination for nut set. almond growers face constant challenges to crop productivity owing to pests and pathogens, which are often controlled with a multitude of agrochemicals. for example, fungicides are often applied in combination with other products to control fungal pathogens during a ... | 2017 | 28334292 |
| population growth of varroa destructor (acari: varroidae) in colonies of russian and unselected honey bee (hymenoptera: apidae) stocks as related to numbers of foragers with mites. | varroa (varroa destructor anderson and trueman) is an external parasite of honey bees (apis mellifera l.) and a leading cause of colony losses worldwide. varroa populations can be controlled with miticides, but mite-resistant stocks such as the russian honey bee (rhb) also are available. russian honey bee and other mite-resistant stocks limit varroa population growth by affecting factors that contribute to mite reproduction. however, mite population growth is not entirely due to reproduction. nu ... | 2017 | 28334279 |
| ecology, life history, and management of tropilaelaps mites. | parasitic mites are the major threat to the western honey bee, apis mellifera l. for much of the world, varroa destructor anderson & trueman single-handedly inflicts unsurmountable problems to a. mellifera beekeeping. however, a. mellifera in asia is also faced with another genus of destructive parasitic mite, tropilaelaps. the life history of these two parasitic mites is very similar, and both have the same food requirements (i.e., hemolymph of developing brood). hence, parasitism by tropilaela ... | 2017 | 28334185 |
| managed bumble bees (bombus impatiens) (hymenoptera: apidae) caged with blueberry bushes at high density did not increase fruit set or fruit weight compared to open pollination. | highbush blueberry (vaccinium corymbosum l.) is an important crop grown throughout florida. currently, most blueberry growers use honey bees (apis mellifera l.) to provide pollination services for highbush blueberries even though bumble bees (bombus spp.) have been shown to be more efficient at pollinating blueberries on a per bee basis. in general, contribution of bumble bees to the pollination of commercial highbush blueberries in florida is unknown. herein, we determined if managed bumble bee ... | 2017 | 28334127 |
| floral strips attract beneficial insects but do not enhance yield in cucumber fields. | natural enemies and pollinators require nutritional and habitat resources that are often not found in conventional agricultural fields. the addition of flowering plants within agroecosystems may provide the resources necessary to support beneficial insects at the local scale. we hypothesized that insect pollinator and natural enemy abundance would increase in cucumber (cucumis sativus) plots containing flower strips and that the effect would be greatest in the crop rows closest to the flower str ... | 2017 | 28334107 |
| honey bee hairs and pollenkitt are essential for pollen capture and removal. | while insect grooming has been observed and documented for over one hundred years, we present the first quantitative analysis of this highly dynamic process. pollinating insects, like honey bees, purposely cover themselves with millions of pollen particles that, if left ungroomed, would make sensing and controlled flight difficult. how do they get clean? we show that the hairs on insect eyes are tuned to the pollen they collect; namely, the hairs are spaced so that they suspend pollen above the ... | 2017 | 28332480 |
| pollinator population size and pollination ecosystem service responses to enhancing floral and nesting resources. | modeling pollination ecosystem services requires a spatially explicit, process-based approach because they depend on both the behavioral responses of pollinators to the amount and spatial arrangement of habitat and on the within- and between-season dynamics of pollinator populations in response to land use. we describe a novel pollinator model predicting flower visitation rates by wild central-place foragers (e.g., nesting bees) in spatially explicit landscapes. the model goes beyond existing ap ... | 2017 | 28331597 |
| a clinical trial protocol to treat massive africanized honeybee (apis mellifera) attack with a new apilic antivenom. | envenomation caused by multiple stings from africanized honeybees apis mellifera constitutes a public health problem in the americas. in 2015, the brazilian ministry of health reported 13,597 accidents (incidence of seven cases per 100,000 inhabitants) with 39 deaths (lethality of 0.25%). the toxins present in the venom, which include melittin and phospholipase a2, cause lesions in diverse organs and systems that may be fatal. as there has been no specific treatment to date, management has been ... | 2017 | 28331487 |
| taxonomy of the african large carpenter bees of the genus xylocopa latreille, 1802, subgenus xenoxylocopa hurd & moure, 1963 (hymenoptera, apidae). | the taxonomy of the genus xylocopa latreille, 1802, subgenus xenoxylocopa hurd & moure, 1963, is reviewed. there is a single valid species in this subgenus, xylocopa (xenoxylocopa) inconstans smith, 1874, which is widely distributed throughout sub-saharan africa, from senegal to ethiopia and south to northern republic of south africa. synonyms of xylocopa inconstans include xylocopa abyssinica radoszkowski, 1899, proposed for a male specimen from ethiopia, as well as three names proposed for fem ... | 2017 | 28331398 |
| the genus amegilla (hymenoptera, apidae, anthophorini) in australia: a revision of the subgenera notomegilla and zonamegilla. | the australian bees in the subgenera notomegilla and zonamegilla of the genus amegilla are revised. commonly in australia the species in these subgenera are called blue-banded bees, although not all species have blue bands. a phylogeny based on mitochondrial cytochrome oxidase 1 sequence data was used to delineate the species and a set of morphological criteria was developed for species identification. strong support was obtained for separating the australian species into the three subgenera pre ... | 2017 | 28331394 |
| linking magnetite in the abdomen of honey bees to a magnetoreceptive function. | previous studies of magnetoreception in honey bees, apis mellifera, focused on the identification of magnetic material, its formation, the location of the receptor and potential underlying sensory mechanisms, but never directly linked magnetic material to a magnetoreceptive function. in our study, we demonstrate that ferromagnetic material consistent with magnetite plays an integral role in the bees' magnetoreceptor. subjecting lyophilized and pelletized bee tagmata to analyses by a superconduct ... | 2017 | 28330921 |
| behavioral, transcriptomic and epigenetic responses to social challenge in honey bees. | understanding how social experiences are represented in the brain and shape future responses is a major challenge in the study of behavior. we addressed this problem by studying behavioral, transcriptomic and epigenetic responses to intrusion in honey bees. previous research showed that initial exposure to an intruder provokes an immediate attack; we now show that this also leads to longer-term changes in behavior in the response to a second intruder, with increases in the probability of respond ... | 2017 | 28328153 |
| neuroscience: intelligence in the honeybee mushroom body. | intelligence, in most people's conception, involves combining pieces of evidence to reach non-obvious conclusions. a recent theoretical study shows that intelligence-like brain functions can emerge from simple neural circuits, in this case the honeybee mushroom body. | 2017 | 28324737 |
| c-type allatostatins mimic stress-related effects of alarm pheromone on honey bee learning and memory recall. | as honey bee populations worldwide are declining there is an urgent need for a deeper understanding of stress reactivity in these important insects. our data indicate that stress responses in bees (apis mellifera l.) may be mediated by neuropeptides identified, on the basis of sequence similarities, as allatostatins (asta, astc and astcc). effects of allatostatin injection are compared with stress-related changes in learning performance induced by the honeybee alarm pheromone, isopentylacetate ( ... | 2017 | 28323874 |
| developmental and loco-like effects of a swainsonine-induced inhibition of α-mannosidase in the honey bee, apis mellifera. | deficiencies in lysosomal a-mannosidase (lam) activity in animals, caused either by mutations or by consuming toxic alkaloids, lead to severe phenotypic and behavioural consequences. yet, epialleles adversely affecting lam expression exist in the honey bee population suggesting that they might be beneficial in certain contexts and cannot be eliminated by natural selection. | 2017 | 28321369 |
| a novel melittin nano-liposome exerted excellent anti-hepatocellular carcinoma efficacy with better biological safety. | melittin is the main effective component of bee venom and has extensive biological functions; however, serious side effects have restricted its clinical application. preclinical and clinical studies showed that the main adverse events were allergic reaction and pain at the administration site. to decrease the toxicity, we prepared melittin nano-liposomes by encapsulating melittin with poloxamer 188 and explored the inhibitory activities on liver cancer together with biological safety. here, we s ... | 2017 | 28320480 |
| is floral morphology a good predictor of floral visitors to antirrhineae (snapdragons and relatives)? | the association between plants and flower visitors has been historically proposed as a main factor driving the evolutionary change of both flower and pollinator phenotypes. the considerable diversity in floral morphology within the tribe antirrhineae has been traditionally related to pollinator types. we used empirical data on the flower visitors from 59 antirrhineae taxa from the literature and our own field surveys, which provide an opportunity to test whether flower phenotypes are reliable pr ... | 2017 | 28316136 |
| octopamine and tyramine modulate the thermoregulatory fanning response in honey bees (apis mellifera l.). | biogenic amines regulate the proximate mechanisms underlying most behavior, including those that contribute to the overall success of complex societies. for honey bees, one critical set of behaviors contributing to the welfare of a colony is involved with nest thermoregulation. worker honeybees cool the colony by performing a fanning behavior, the expression of which is largely influenced by response thresholds modulated by the social environment. here, we examined how changes in biogenic amines ... | 2017 | 28314750 |
| insights into the role of age and social interactions on the sexual attractiveness of queens in an eusocial bee, melipona flavolineata (apidae, meliponini). | the attraction of sexual partners is a vital necessity among insects, and it involves conflict of interests and complex communication systems among male and female. in this study, we investigated the developing of sexual attractiveness in virgin queens (i.e., gynes) of melipona flavolineata, an eusocial stingless bee. we followed the development of sexual attractiveness in 64 gynes, belonging to seven age classes (0, 3, 6, 9, 15, 18 days post-emergence), and we also evaluated the effect of diffe ... | 2017 | 28299419 |
| multifractality in individual honeybee behavior hints at colony-specific social cascades: reanalysis of radio-frequency identification data from five different colonies. | honeybees (apis mellifera) exhibit complex coordination and interaction across multiple behaviors such as swarming. this coordination among honeybees in the same colony is remarkably similar to the concept of informational cascades. the multifractal geometry of cascades suggests that multifractal measures of individual honeybee activity might carry signatures of these colony-wide coordinations. the present work reanalyzes time stamps of entrances to and exits from the hive captured by radio-freq ... | 2017 | 28297945 |
| stingless bee honey, the natural wound healer: a review. | the stingless bee is a natural type of bee that exists in almost every continent. the honey produced by this bee has been widely used across time and space. the distinctive feature of this honey is that it is stored naturally in the pot (cerumen), thus contributing to its beneficial properties, especially in the wound healing process. | 2017 | 28291965 |
| antibiotic exposure perturbs the gut microbiota and elevates mortality in honeybees. | gut microbiomes play crucial roles in animal health, and shifts in the gut microbial community structure can have detrimental impacts on hosts. studies with vertebrate models and human subjects suggest that antibiotic treatments greatly perturb the native gut community, thereby facilitating proliferation of pathogens. in fact, persistent infections following antibiotic treatment are a major medical issue. in apiculture, antibiotics are frequently used to prevent bacterial infections of larval be ... | 2017 | 28291793 |
| firewalls in bee nests-survival value of propolis walls of wild cape honeybee (apis mellifera capensis). | the cape bee is endemic to the winter rainfall region of south africa where fires are an integral part of the ecology of the fynbos (heathland) vegetation. of the 37 wild nests in pristine peninsula sandstone fynbos in the cape point section of table mountain national park that have been analyzed so far, only 22 could be accessed sufficiently to determine the existence of a propolis wall of which 68% had propolis walls which entirely enclosed their openings. the analysis of the 37 wild nests rev ... | 2017 | 28289772 |
| stress-mediated allee effects can cause the sudden collapse of honey bee colonies. | the recent rapid decline in global honey bee populations could have significant implications for ecological systems, economics and food security. no single cause of honey bee collapse has yet to be identified, although pesticides, mites and other pathogens have all been shown to have a sublethal effect. we present a model of a functioning bee hive and introduce external stress to investigate the impact on the regulatory processes of recruitment to the forager class, social inhibition and the lay ... | 2017 | 28288794 |
| taxonomic and functional trait diversity of wild bees in different urban settings. | urbanization is one of the major anthropogenic processes contributing to local habitat loss and extirpation of numerous species, including wild bees, the most widespread pollinators. little is known about the mechanisms through which urbanization impacts wild bee communities, or the types of urban green spaces that best promote their conservation in cities. the main objective of this study was to describe and compare wild bee community diversity, structure, and dynamics in two canadian cities, m ... | 2017 | 28286711 |
| effects of bee propolis supplementation on glycemic control, lipid profile and insulin resistance indices in patients with type 2 diabetes: a randomized, double-blind clinical trial. | propolis, a natural resinous substance made by bees from material extracted from plants, flowers and bee's wax, has shown great therapeutic effects and been widely used in food and drug industries. recently, some researchers have studied the effect of this substance in the treatment of diabetes. | 2017 | 28285617 |
| pharmacist use of the electronic medical record to identify adults at risk for anaphylaxis without epinephrine for self-administration. | to describe an innovative pharmacist-led approach, with the use of electronic medical record (emr) data, to identify patients at risk of anaphylaxis in need of epinephrine auto-injector (eai) for self-administration. | 2017 | 28285065 |
| agricultural pesticides and veterinary substances in uruguayan beeswax. | over the last decade, uruguay has expanded and intensified its rainfed crop production. this process has affected beekeeping in several ways: for example, by reducing the space available. this has increased the density of apiaries, the risk of varroosis and acaricide use. additionally, the dominance of no-tillage crops has increased the frequencies of application and of loads of pesticides in regions where such crops share the land with beekeeping and honey production. therefore, the exposure of ... | 2017 | 28284118 |