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argentinean propolis from zuccagnia punctata cav. (caesalpinieae) exudates: phytochemical characterization and antifungal activity.this paper reports the in vitro antifungal activity of propolis extracts from the province of tucuman (argentina) as well as the identification of their main antifungal compounds and botanical origin. the antifungal activity was determined by the microdilution technique, using reference microorganisms and clinical isolates. all dermatophytes and yeasts tested were strongly inhibited by different propolis extracts (mics between 16 and 125 microg ml(-1)). the most susceptible species were microspo ...201019916546
argentinean propolis from zuccagnia punctata cav. (caesalpinieae) exudates: phytochemical characterization and antifungal activity.this paper reports the in vitro antifungal activity of propolis extracts from the province of tucuman (argentina) as well as the identification of their main antifungal compounds and botanical origin. the antifungal activity was determined by the microdilution technique, using reference microorganisms and clinical isolates. all dermatophytes and yeasts tested were strongly inhibited by different propolis extracts (mics between 16 and 125 microg ml(-1)). the most susceptible species were microspo ...201019916546
cd4+ and cd8+ t cells mediated direct cytotoxic effect against trichophyton rubrum and trichophyton mentagrophytes.the cellular immune system is the most dominant factor in curing acute dermatophytosis. however, the exact immune mechanisms involved in generating this defense are complex and still obscure. the aim of this study was to investigate the fungicidal mechanism of t cells in the normal population versus patients with chronic fungal infections.201019968718
cd4+ and cd8+ t cells mediated direct cytotoxic effect against trichophyton rubrum and trichophyton mentagrophytes.the cellular immune system is the most dominant factor in curing acute dermatophytosis. however, the exact immune mechanisms involved in generating this defense are complex and still obscure. the aim of this study was to investigate the fungicidal mechanism of t cells in the normal population versus patients with chronic fungal infections.201019968718
composition and biological activity of the essential oil from leaves of plinia cerrocampanensis, a new source of alpha-bisabolol.the essential oil from fresh leaves of plinia cerrocampanensis barrie (myrtaceae), obtained by hydrodistillation, was analysed by gc-fid and gc-ms. forty components, representing more than 91% of the oil, were identified. oxygenated sesquiterpenes represented the main fraction with alpha-bisabolol (42.8%) as the major constituent, making this plant a new and good source of this substance. biological activity of the essential oil was evaluated against several bacterial and fungal strains as well ...201020015638
composition and biological activity of the essential oil from leaves of plinia cerrocampanensis, a new source of alpha-bisabolol.the essential oil from fresh leaves of plinia cerrocampanensis barrie (myrtaceae), obtained by hydrodistillation, was analysed by gc-fid and gc-ms. forty components, representing more than 91% of the oil, were identified. oxygenated sesquiterpenes represented the main fraction with alpha-bisabolol (42.8%) as the major constituent, making this plant a new and good source of this substance. biological activity of the essential oil was evaluated against several bacterial and fungal strains as well ...201020015638
synthesis, structure, and antifungal evaluation of some novel 1,2,4-triazolylmercaptoacetylthiosemicarbazide and 1,2,4-triazolylmercaptomethyl-1,3,4-thiadiazole analogs.novel 1-[[4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-yl]mercaptoacetyl]-4-alkyl/aryl-3-thiosemicarbazides (5-12) were synthesized by the reaction of 4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-ylmercaptoacetylhydrazide (4) with substituted isothiocyanates. cyclodehydration of thiosemicarbazides with concentrated sulfuric acid yielded 2-[4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-yl]mercaptomethyl-5-alkyl/arylamino-1,3, 4-thiadiazoles (13-17). the new compounds were evaluated ...201020030516
synthesis, structure, and antifungal evaluation of some novel 1,2,4-triazolylmercaptoacetylthiosemicarbazide and 1,2,4-triazolylmercaptomethyl-1,3,4-thiadiazole analogs.novel 1-[[4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-yl]mercaptoacetyl]-4-alkyl/aryl-3-thiosemicarbazides (5-12) were synthesized by the reaction of 4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-ylmercaptoacetylhydrazide (4) with substituted isothiocyanates. cyclodehydration of thiosemicarbazides with concentrated sulfuric acid yielded 2-[4-(4-bromophenyl)-5-(2-furyl)-4h-1,2,4-triazole-3-yl]mercaptomethyl-5-alkyl/arylamino-1,3, 4-thiadiazoles (13-17). the new compounds were evaluated ...201020030516
cutaneous mycoflora and cd4:cd8 ratio of cats infected with feline immunodeficiency virus.this study was designed to compare cutaneous mycoflora isolation and cd4+:cd8+ ratio in feline immunodeficiency virus (fiv)-infected cats with that in fiv-uninfected cats. sixty cats were examined. twenty-five were fiv-infected cats and 35 were fiv-uninfected cats. all 60 cats were felv-negative. fungi were speciated and immunophenotyping of peripheral cd4+ and cd8+ t lymphocytes was performed. at least one fungal colony was isolated from 22/25 (88%) fiv-infected cats. among the fiv-uninfected c ...201020156698
cutaneous mycoflora and cd4:cd8 ratio of cats infected with feline immunodeficiency virus.this study was designed to compare cutaneous mycoflora isolation and cd4+:cd8+ ratio in feline immunodeficiency virus (fiv)-infected cats with that in fiv-uninfected cats. sixty cats were examined. twenty-five were fiv-infected cats and 35 were fiv-uninfected cats. all 60 cats were felv-negative. fungi were speciated and immunophenotyping of peripheral cd4+ and cd8+ t lymphocytes was performed. at least one fungal colony was isolated from 22/25 (88%) fiv-infected cats. among the fiv-uninfected c ...201020156698
historical aspects of dermatomycoses.physicians have been aware of superficial fungal infections for centuries, but the causal agents and treatments of fungal infections remained unknown until the mid-1800s, when numerous important findings were reported. among the relevant researchers in the field of superficial mycoses were remak, who found the fungal nature of favus in 1837; berg, who reported oral candidosis in 1841; and wilkinson, who described vaginal candidosis in 1849. tinea versicolor was described clinically in 1846 by ei ...201020347652
historical aspects of dermatomycoses.physicians have been aware of superficial fungal infections for centuries, but the causal agents and treatments of fungal infections remained unknown until the mid-1800s, when numerous important findings were reported. among the relevant researchers in the field of superficial mycoses were remak, who found the fungal nature of favus in 1837; berg, who reported oral candidosis in 1841; and wilkinson, who described vaginal candidosis in 1849. tinea versicolor was described clinically in 1846 by ei ...201020347652
incidence of keratinophilic fungi from the soils of vedanthangal water bird sanctuary (india).summary fifty-three soil samples were collected from various sites in the vicinity of vedanthangal water bird sanctuary and screened for the presence of keratinophilic fungi using the hair baiting techniques for isolation. twenty-eight isolates were recovered and identified by recognition of their macro- and micromorphological features. seven species related to five genera were recorded viz. auxarthron conjugatum (1.89%), chrysosporium fluviale (3.77%), chrysosporium indicum (20.75%), chrysospor ...201020406397
incidence of keratinophilic fungi from the soils of vedanthangal water bird sanctuary (india).summary fifty-three soil samples were collected from various sites in the vicinity of vedanthangal water bird sanctuary and screened for the presence of keratinophilic fungi using the hair baiting techniques for isolation. twenty-eight isolates were recovered and identified by recognition of their macro- and micromorphological features. seven species related to five genera were recorded viz. auxarthron conjugatum (1.89%), chrysosporium fluviale (3.77%), chrysosporium indicum (20.75%), chrysospor ...201020406397
antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from superficial skin infection.antimicrobial activity of solvent extracts of leaves and shoot of dodonaea viscosa jacq have been determined against fungi, aspergillus niger, aspergillus flavus, paecilomyces varioti, microsporum gypseum, and trichophyton rubrum causing skin diseases. all crude extracts were found to be effective against tested fungi. however chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous extracts. more over in present study some basic elements ...201020566450
antifungal activity of dodonaea viscosa jacq extract on pathogenic fungi isolated from superficial skin infection.antimicrobial activity of solvent extracts of leaves and shoot of dodonaea viscosa jacq have been determined against fungi, aspergillus niger, aspergillus flavus, paecilomyces varioti, microsporum gypseum, and trichophyton rubrum causing skin diseases. all crude extracts were found to be effective against tested fungi. however chloroform has strong inhibition activity against fungi as compared to ethanol, methanol, ethylacetate and aqueous extracts. more over in present study some basic elements ...201020566450
identification and characterisation of human pathogenic filamentous fungi and susceptibility to thymus schimperi essential oil.summary twenty-eight clinical fungal isolates were characterised by morphological (macro- and micro-features and growth response at 25, 30 and 37 degrees c) and molecular (nuclear rdna-internal transcriber spacer, calmodulin, cytochrome c oxidase 1 and the largest subunit of rna polymerase ii) analyses. the clinical fungal isolates were ascribed to the following taxa: penicillium chrysogenum, verticillium sp., aspergillus tubingensis, aspergillus minutus, beauveria bassiana and microsporum gypse ...201020633233
identification and characterisation of human pathogenic filamentous fungi and susceptibility to thymus schimperi essential oil.summary twenty-eight clinical fungal isolates were characterised by morphological (macro- and micro-features and growth response at 25, 30 and 37 degrees c) and molecular (nuclear rdna-internal transcriber spacer, calmodulin, cytochrome c oxidase 1 and the largest subunit of rna polymerase ii) analyses. the clinical fungal isolates were ascribed to the following taxa: penicillium chrysogenum, verticillium sp., aspergillus tubingensis, aspergillus minutus, beauveria bassiana and microsporum gypse ...201020633233
antifungal activity of extracts and prenylated coumarins isolated from baccharis darwinii hook & arn. (asteraceae).the petroleum ether extract of baccharis darwinii showed activity against cryptococcus neoformans and dermatophytes. bioactivity-guided fractionation of baccharis darwinii has resulted in the isolation of three coumarins: 5'-hydroxy aurapten (anisocoumarin h, 1), aurapten (7-geranyloxycoumarin, 2) and 5'-oxoaurapten (diversinin, 3). the structures of these compounds were characterized by spectroscopic methods. these compounds were evaluated for their antimicrobialactivity against a panel of each ...201020657398
antifungal activity of extracts and prenylated coumarins isolated from baccharis darwinii hook & arn. (asteraceae).the petroleum ether extract of baccharis darwinii showed activity against cryptococcus neoformans and dermatophytes. bioactivity-guided fractionation of baccharis darwinii has resulted in the isolation of three coumarins: 5'-hydroxy aurapten (anisocoumarin h, 1), aurapten (7-geranyloxycoumarin, 2) and 5'-oxoaurapten (diversinin, 3). the structures of these compounds were characterized by spectroscopic methods. these compounds were evaluated for their antimicrobialactivity against a panel of each ...201020657398
extensive neonatal dermatophytoses.we report a 25-day-old boy who was referred to our dermatology unit for evaluation of extensive annular erythematous lesions on his body. we initially considered the differential diagnoses of candidiasis and neonatal lupus erythematosus but investigations revealed the case as tinea corporis due to a relatively uncommon causative agent, microsporum gypseum. to the best of our knowledge it is the first case of extensive neonatal dermatophytoses caused by this organism. the possible causes and the ...201019686303
extensive neonatal dermatophytoses.we report a 25-day-old boy who was referred to our dermatology unit for evaluation of extensive annular erythematous lesions on his body. we initially considered the differential diagnoses of candidiasis and neonatal lupus erythematosus but investigations revealed the case as tinea corporis due to a relatively uncommon causative agent, microsporum gypseum. to the best of our knowledge it is the first case of extensive neonatal dermatophytoses caused by this organism. the possible causes and the ...201019686303
antagonism of microsporum species by soil fungi.eighteen fungi isolated from soil by hair bating method were tested against soil inhabiting microsporum equinum, microsporum fulvum, microsporum gypseum and microsporum racemosum for their antagonistic interactions. colony inhibition during dual cultures showed inhibition of all the four microsporum species. the maximum inhibition of m. equinum, m. fulvum, m. gypseum and m. racemosum was caused by chrysosporium keratinophilum, chrysosporium tropicum, curvularia lunata and chrysosporium lucknowen ...201019207833
antagonism of microsporum species by soil fungi.eighteen fungi isolated from soil by hair bating method were tested against soil inhabiting microsporum equinum, microsporum fulvum, microsporum gypseum and microsporum racemosum for their antagonistic interactions. colony inhibition during dual cultures showed inhibition of all the four microsporum species. the maximum inhibition of m. equinum, m. fulvum, m. gypseum and m. racemosum was caused by chrysosporium keratinophilum, chrysosporium tropicum, curvularia lunata and chrysosporium lucknowen ...201019207833
dermatophytes in republic of macedonia.(full text is available at http://www.manu.edu.mk/prilozi). a total of 1742 clinically suspected samples was examined for the incidence and distribution of dermatophytes in the republic of macedonia from june 2007 to jan. 2009. 600 dermatophytes were isolated and identified. in the studied period 9 different dermatophyte species were isolated, namely trichophyton rubrum (48.83%), microsporum canis (20%), trichophyton mentagrophytes var. interdigitale (16.83%), epidermophyton floccosum (4.17%), t ...201020693949
dermatophytes in republic of macedonia.(full text is available at http://www.manu.edu.mk/prilozi). a total of 1742 clinically suspected samples was examined for the incidence and distribution of dermatophytes in the republic of macedonia from june 2007 to jan. 2009. 600 dermatophytes were isolated and identified. in the studied period 9 different dermatophyte species were isolated, namely trichophyton rubrum (48.83%), microsporum canis (20%), trichophyton mentagrophytes var. interdigitale (16.83%), epidermophyton floccosum (4.17%), t ...201020693949
strange formation of n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one and its oxime derivative--synthesis, stereochemistry, antibacterial and antifungal activity.objectives and methods: a collection of novel n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one oximes 28-32 are synthesized, characterized by melting point, elemental analysis, ms, ft-ir, one-dimensional nmr (1h & 13c) and two dimensional noesy spectroscopic data and evaluate for their in vitro antibacterial and antifungal activities. results and conclusion: compound 32, exerted a wide range of antibacterial activities against the entire tested gram-positive and gram-negative bacterial strains e ...201020707249
strange formation of n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one and its oxime derivative--synthesis, stereochemistry, antibacterial and antifungal activity.objectives and methods: a collection of novel n-hydroxy-3,3-dimethyl-2,6-diarylpiperidin-4-one oximes 28-32 are synthesized, characterized by melting point, elemental analysis, ms, ft-ir, one-dimensional nmr (1h & 13c) and two dimensional noesy spectroscopic data and evaluate for their in vitro antibacterial and antifungal activities. results and conclusion: compound 32, exerted a wide range of antibacterial activities against the entire tested gram-positive and gram-negative bacterial strains e ...201020707249
superficial fungal infections seen at a tertiary health centre: clinical and mycological studies.superficial fungal infections are common in the tropics, partly due to the climate, relatively poor hygiene, and lifestyle of the people.201020931516
superficial fungal infections seen at a tertiary health centre: clinical and mycological studies.superficial fungal infections are common in the tropics, partly due to the climate, relatively poor hygiene, and lifestyle of the people.201020931516
extracellular protease expression in microsporum gypseum complex, its regulation and keratinolytic potential.two soil isolates of microsporum gypseum were studied for the production of extracellular proteases. both the strains secreted protease on glucose-gelatin medium. the enzyme activity peaked on day 15 at 28 °c. asparagine repressed protease yield. sugars caused catabolite repression of protease formation. protease activities of both the isolates were significantly affected by incubation period, culture media and carbohydrates used. both the strains grew on the skin bait and caused a gravimetrical ...201020946260
extracellular protease expression in microsporum gypseum complex, its regulation and keratinolytic potential.two soil isolates of microsporum gypseum were studied for the production of extracellular proteases. both the strains secreted protease on glucose-gelatin medium. the enzyme activity peaked on day 15 at 28 °c. asparagine repressed protease yield. sugars caused catabolite repression of protease formation. protease activities of both the isolates were significantly affected by incubation period, culture media and carbohydrates used. both the strains grew on the skin bait and caused a gravimetrical ...201020946260
chemical composition and biological assays of essential oils of calamintha nepeta (l.) savi subsp. nepeta (lamiaceae).aerial parts of wild calamintha nepeta (l.) savi subsp. nepeta growing spontaneously on the mediterranean coast (sardinia island, italy) and on the atlantic coast (portugal) were used as a matrix for the supercritical extraction of volatile oil with co(2). the collected extracts were analysed by gc-fid and gc-ms methods and their compositions were compared with that of the essential oil isolated by hydrodistillation, but the differences were not relevant. a strong chemical variability was observ ...201020981614
chemical composition and biological assays of essential oils of calamintha nepeta (l.) savi subsp. nepeta (lamiaceae).aerial parts of wild calamintha nepeta (l.) savi subsp. nepeta growing spontaneously on the mediterranean coast (sardinia island, italy) and on the atlantic coast (portugal) were used as a matrix for the supercritical extraction of volatile oil with co(2). the collected extracts were analysed by gc-fid and gc-ms methods and their compositions were compared with that of the essential oil isolated by hydrodistillation, but the differences were not relevant. a strong chemical variability was observ ...201020981614
effects of temperature variations and light exposure on the time to growth of dermatophytes using six different fungal culture media inoculated with laboratory strains and samples obtained from infected cats.in this study, 5/6 commercially available fungal culture media were comparable with respect to first growth, first colour change, and first sporulation when inoculated with three strains of microsporum canis, one strain of microsporum gypseum, and one strain of trichophyton species when incubated at either 25°c or 30°c. five of six plates showed 100% growth at both temperatures. five of six plates showed 100% growth when inoculated with naturally infective m canis hairs and spores. one commercia ...201021051255
effects of temperature variations and light exposure on the time to growth of dermatophytes using six different fungal culture media inoculated with laboratory strains and samples obtained from infected cats.in this study, 5/6 commercially available fungal culture media were comparable with respect to first growth, first colour change, and first sporulation when inoculated with three strains of microsporum canis, one strain of microsporum gypseum, and one strain of trichophyton species when incubated at either 25°c or 30°c. five of six plates showed 100% growth at both temperatures. five of six plates showed 100% growth when inoculated with naturally infective m canis hairs and spores. one commercia ...201021051255
sequenced dermatophyte strains: growth rate, conidiation, drug susceptibilities, and virulence in an invertebrate model.although dermatophytes are the most common cause of fungal infections in the world, their basic biology is not well understood. the recent sequencing and annotation of the genomes of five representative dermatophyte species allows for the creation of hypotheses as to how they cause disease and have adapted to their distinct environments. an understanding of the microbiology of these strains will be essential for testing these hypotheses. this study is the first to generally characterize these fi ...201021145410
sequenced dermatophyte strains: growth rate, conidiation, drug susceptibilities, and virulence in an invertebrate model.although dermatophytes are the most common cause of fungal infections in the world, their basic biology is not well understood. the recent sequencing and annotation of the genomes of five representative dermatophyte species allows for the creation of hypotheses as to how they cause disease and have adapted to their distinct environments. an understanding of the microbiology of these strains will be essential for testing these hypotheses. this study is the first to generally characterize these fi ...201021145410
studies on antidermatophytic activity of waste leaves of curcuma longa l.during antidermatophytic screening of some essential oils, curcuma longa l. exhibited the strongest antifungal activity, completely inhibiting the mycelial growth of ringworm, caused by the fungi- microsporum gypseum and trichophyton mentagrophytes. the essential oil from leaves of curcuma longa was fungicidal at 2.5 μl/ml at which it tolerated heavy doses of inoculum. the fungicidal activity of the oil was thermostable up to 80 °c and self life up to 24 months in storage. the oil also showed a ...201023572967
studies on antidermatophytic activity of waste leaves of curcuma longa l.during antidermatophytic screening of some essential oils, curcuma longa l. exhibited the strongest antifungal activity, completely inhibiting the mycelial growth of ringworm, caused by the fungi- microsporum gypseum and trichophyton mentagrophytes. the essential oil from leaves of curcuma longa was fungicidal at 2.5 μl/ml at which it tolerated heavy doses of inoculum. the fungicidal activity of the oil was thermostable up to 80 °c and self life up to 24 months in storage. the oil also showed a ...201023572967
tinea incognito due to microsporum gypseum.a 41-year-old woman presented with a pruritic rash on the face that was of 3 months duration. during that time, it had been successively misdiagnosed as psoriasis vulgaris, systemic lupus erythematosus, facial dermatitis at other hospitals, and had been treated with agents that included acitretin and prednisone. finally, fungi were found in the lesions by optical microscopy, and the fungal culture was positive for microsporum gypseum, and was diagnosed as a microsporum gypseum infection. the les ...201023554617
tinea incognito due to microsporum gypseum.a 41-year-old woman presented with a pruritic rash on the face that was of 3 months duration. during that time, it had been successively misdiagnosed as psoriasis vulgaris, systemic lupus erythematosus, facial dermatitis at other hospitals, and had been treated with agents that included acitretin and prednisone. finally, fungi were found in the lesions by optical microscopy, and the fungal culture was positive for microsporum gypseum, and was diagnosed as a microsporum gypseum infection. the les ...201023554617
fungal microbiota from ocular conjuctiva of clinically healthy horses belonging to the military police cavalry of alagoas.normal fungal conjunctiva microbiota of horses remains stable in healthy animals, free from ocular and/or systemic diseases which may, eventually, cause ocular alterations. the knowledge of the fungal microbiota is of great importance due to the reduced number of studies reported in the literature and also to the large occurrence of ocular alterations, mainly keratomycosis, in these animals. the aim of this study was to isolate and to identify the fungi present in the ocular conjunctiva of healt ...201124031735
fungal microbiota from ocular conjuctiva of clinically healthy horses belonging to the military police cavalry of alagoas.normal fungal conjunctiva microbiota of horses remains stable in healthy animals, free from ocular and/or systemic diseases which may, eventually, cause ocular alterations. the knowledge of the fungal microbiota is of great importance due to the reduced number of studies reported in the literature and also to the large occurrence of ocular alterations, mainly keratomycosis, in these animals. the aim of this study was to isolate and to identify the fungi present in the ocular conjunctiva of healt ...201124031735
synthesis and in vitro microbiological evaluation of novel diethyl 6,6'-(1,4-phenylene)bis(4-aryl-2-oxo-cyclohex-3-enecarboxylates).novel bis cyclohexenone ester derivatives 14-19 were synthesized and characterized by their spectral data. in vitro microbiological evaluations were carried out for all the novel compounds 14-19 against clinically isolated bacterial and fungal strains. compounds 15, 16, 18 against staphylococcus aureus, 14, 15 against ß-haemolytic streptococcus, 15, 19 against micrococcus luteus, 17, 18 against salmonella typhii, 14, 17 against shigella flexneri, 15 against escherichia coli, 16 against pseudomon ...201121417963
synthesis and in vitro microbiological evaluation of novel diethyl 6,6'-(1,4-phenylene)bis(4-aryl-2-oxo-cyclohex-3-enecarboxylates).novel bis cyclohexenone ester derivatives 14-19 were synthesized and characterized by their spectral data. in vitro microbiological evaluations were carried out for all the novel compounds 14-19 against clinically isolated bacterial and fungal strains. compounds 15, 16, 18 against staphylococcus aureus, 14, 15 against ß-haemolytic streptococcus, 15, 19 against micrococcus luteus, 17, 18 against salmonella typhii, 14, 17 against shigella flexneri, 15 against escherichia coli, 16 against pseudomon ...201121417963
tinea incognito caused by microsporum gypseum in a patient with advanced hiv infection: a case report.the prevalence and the clinical relevance of dermatophytoses in hiv-infected patients are poorly documented, particularly for those caused by tinea incognito. here, we report a case of widespread facial tinea incognito occurring in an italian patient with advanced hiv infection, showing both skin and brain lesions. second-line treatment with liposomal amphotericin b and cotrimoxazole, administered after a microbiological characterization of the skin scrapings, led to complete clearance of all le ...201121487462
tinea incognito caused by microsporum gypseum in a patient with advanced hiv infection: a case report.the prevalence and the clinical relevance of dermatophytoses in hiv-infected patients are poorly documented, particularly for those caused by tinea incognito. here, we report a case of widespread facial tinea incognito occurring in an italian patient with advanced hiv infection, showing both skin and brain lesions. second-line treatment with liposomal amphotericin b and cotrimoxazole, administered after a microbiological characterization of the skin scrapings, led to complete clearance of all le ...201121487462
essential oils of medicinal plants from the central andes of argentina: chemical composition, and antifungal, antibacterial, and insect-repellent activities.the antifungal, antibacterial, and insect-repellent activities of the essential oils (eos) of acantholippia seriphioides, artemisia mendozana, gymnophyton polycephalum, satureja parvifolia, tagetes mendocina, and lippia integrifolia, collected in the central andes area, province of san juan, argentina, were investigated. the dermatophytes microsporum gypseum, trichophyton mentagrophytes, and t. rubrum were inhibited by the eos of g. polycephalum, l. integrifolia, and s. parvifolia, with minimum ...201121560241
essential oils of medicinal plants from the central andes of argentina: chemical composition, and antifungal, antibacterial, and insect-repellent activities.the antifungal, antibacterial, and insect-repellent activities of the essential oils (eos) of acantholippia seriphioides, artemisia mendozana, gymnophyton polycephalum, satureja parvifolia, tagetes mendocina, and lippia integrifolia, collected in the central andes area, province of san juan, argentina, were investigated. the dermatophytes microsporum gypseum, trichophyton mentagrophytes, and t. rubrum were inhibited by the eos of g. polycephalum, l. integrifolia, and s. parvifolia, with minimum ...201121560241
melanogenesis in dermatophyte species in vitro and during infection.dermatophytes are keratinophilic fungi that are the most common cause of fungal skin infections worldwide. melanin has been isolated from several important human fungal pathogens and the polymeric pigment is now recognized as an important virulence determinant. this study investigated whether dermatophytes, including trichophyton rubrum, t. mentagrophytes, epidermophyton floccosum, and microsporum gypseum, produce melanin or melanin-like compounds in vitro and during infection. digestion of the ...201121565930
melanogenesis in dermatophyte species in vitro and during infection.dermatophytes are keratinophilic fungi that are the most common cause of fungal skin infections worldwide. melanin has been isolated from several important human fungal pathogens and the polymeric pigment is now recognized as an important virulence determinant. this study investigated whether dermatophytes, including trichophyton rubrum, t. mentagrophytes, epidermophyton floccosum, and microsporum gypseum, produce melanin or melanin-like compounds in vitro and during infection. digestion of the ...201121565930
argentinean andean propolis associated with the medicinal plant larrea nitida cav. (zygophyllaceae). hplc-ms and gc-ms characterization and antifungal activity.the chemical profile and botanical origin of andean argentinian propolis were studied by hplc-esi-ms/ms and gc-ms techniques as well as the antifungal activity according to clsi protocols. dermatophytes and yeasts tested were strongly inhibited by propolis extracts (mics between 31.25 and 125μg/ml). the main antifungal compounds were: 3'methyl-nordihydroguaiaretic acid (mndga) 1, nordihydroguaiaretic acid (ndga) 2 and a ndga derivative 3, showing strong activity against trichophyton mentagrophyt ...201121600954
argentinean andean propolis associated with the medicinal plant larrea nitida cav. (zygophyllaceae). hplc-ms and gc-ms characterization and antifungal activity.the chemical profile and botanical origin of andean argentinian propolis were studied by hplc-esi-ms/ms and gc-ms techniques as well as the antifungal activity according to clsi protocols. dermatophytes and yeasts tested were strongly inhibited by propolis extracts (mics between 31.25 and 125μg/ml). the main antifungal compounds were: 3'methyl-nordihydroguaiaretic acid (mndga) 1, nordihydroguaiaretic acid (ndga) 2 and a ndga derivative 3, showing strong activity against trichophyton mentagrophyt ...201121600954
antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro.the antifungal activity of eight pyrazolo[3,4-c]isothiazole derivatives was evaluated on five dermatophytes: three were of an anthropophilic species (i.e., epidermophyton floccosum, trichophyton rubrum, and trichophyton tonsurans) and two were of a geophilic species (i.e., microsporum gypseum and nannizzia cajetani). the new compounds proved to be unlikely effective in inhibiting the growth of the different strains. in general, the fungi parasitic on man were more sensitive than the geophilic sp ...201121649488
antidermatophytic activity of pyrazolo[3,4-c]isothiazoles: a preliminary approach on 4-chlorophenyl derivative for evaluation of mutagenic and clastogenic effects on bacteria and human chromosomes in vitro.the antifungal activity of eight pyrazolo[3,4-c]isothiazole derivatives was evaluated on five dermatophytes: three were of an anthropophilic species (i.e., epidermophyton floccosum, trichophyton rubrum, and trichophyton tonsurans) and two were of a geophilic species (i.e., microsporum gypseum and nannizzia cajetani). the new compounds proved to be unlikely effective in inhibiting the growth of the different strains. in general, the fungi parasitic on man were more sensitive than the geophilic sp ...201121649488
modiolide and pyrone derivatives from the sea fan-derived fungus curvularia sp. psu-f22.investigation of secondary metabolites from the sea fan-derived fungus curvularia sp. psu-f22 resulted in isolation of three new metabolites, curvulapyrone (1), curvulalide (2) and curvulalic acid (3) together with six known compounds, modiolides a (4) and b (5), pyrenolide a (6), stagonolide e (7), mycoepoxydiene (8), and deacetylmycoepoxydiene (9). their antimicrobial activity against staphylococcus aureus atcc 25923, methicillin-resistant s. aureus and microsporum gypseum sh-mu-4 were examine ...201121656354
modiolide and pyrone derivatives from the sea fan-derived fungus curvularia sp. psu-f22.investigation of secondary metabolites from the sea fan-derived fungus curvularia sp. psu-f22 resulted in isolation of three new metabolites, curvulapyrone (1), curvulalide (2) and curvulalic acid (3) together with six known compounds, modiolides a (4) and b (5), pyrenolide a (6), stagonolide e (7), mycoepoxydiene (8), and deacetylmycoepoxydiene (9). their antimicrobial activity against staphylococcus aureus atcc 25923, methicillin-resistant s. aureus and microsporum gypseum sh-mu-4 were examine ...201121656354
Substituted 2-aminothiophenes: antifungal activities and effect on Microsporum gypseum protein profile.The increasing recognition and importance of fungal infections, the difficulties encountered in their treatment and the increase in resistance to antifungal agents have stimulated the search for therapeutic alternatives. The objective of this study was to evaluate the antifungal activities of three substituted 2-aminothiophenes (1, 2 and 3) against some fungal species. The synthesis of substituted 2-aminothiophenes was carried out through the most versatile synthetic method developed by Gewald e ...201121831103
Substituted 2-aminothiophenes: antifungal activities and effect on Microsporum gypseum protein profile.The increasing recognition and importance of fungal infections, the difficulties encountered in their treatment and the increase in resistance to antifungal agents have stimulated the search for therapeutic alternatives. The objective of this study was to evaluate the antifungal activities of three substituted 2-aminothiophenes (1, 2 and 3) against some fungal species. The synthesis of substituted 2-aminothiophenes was carried out through the most versatile synthetic method developed by Gewald e ...201121831103
antifungal activity of different neem leaf extracts and the nimonol against some important human pathogens.this study was conducted to evaluate the effect of aqueous, ethanolic and ethyl acetate extracts from neem leaves on growth of some human pathogens (aspergillus flavus, aspergillus fumigatus, aspergillus niger, aspergillus terreus, candida albicans and microsporum gypseum) in vitro. different concentrations (5, 10, 15 and 20%) prepared from these extracts inhibited the growth of the test pathogens and the effect gradually increased with concentration. the 20% ethyl acetate extract gave the stron ...201124031718
antifungal activity of different neem leaf extracts and the nimonol against some important human pathogens.this study was conducted to evaluate the effect of aqueous, ethanolic and ethyl acetate extracts from neem leaves on growth of some human pathogens (aspergillus flavus, aspergillus fumigatus, aspergillus niger, aspergillus terreus, candida albicans and microsporum gypseum) in vitro. different concentrations (5, 10, 15 and 20%) prepared from these extracts inhibited the growth of the test pathogens and the effect gradually increased with concentration. the 20% ethyl acetate extract gave the stron ...201124031718
evaluation of antifungal activity in essential oil of the syzygium aromaticum (l.) by extraction, purification and analysis of its main component eugenol.antifungal properties of some essential oils have been well documented. clove oil is reported to have strong antifungal activity against many fungal species. in this study we have evaluated antifungal potential of essential oil of syzygium aromaticum (l.) against some common fungal pathogens of plants and animals namely, fusarium moniliforme ncim 1100, fusarium oxysporum mtcc 284, aspergillus sp., mucor sp., trichophyton rubrum and microsporum gypseum. all fungal species were found to be inhibit ...201124031751
evaluation of antifungal activity in essential oil of the syzygium aromaticum (l.) by extraction, purification and analysis of its main component eugenol.antifungal properties of some essential oils have been well documented. clove oil is reported to have strong antifungal activity against many fungal species. in this study we have evaluated antifungal potential of essential oil of syzygium aromaticum (l.) against some common fungal pathogens of plants and animals namely, fusarium moniliforme ncim 1100, fusarium oxysporum mtcc 284, aspergillus sp., mucor sp., trichophyton rubrum and microsporum gypseum. all fungal species were found to be inhibit ...201124031751
a case of kerion celsi caused by microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident.we report a rare case of kerion celsi of the scalp caused by microsporum gypseum in a boy 1 month after he received dermatoplasty for a scalp injury from a road accident. species identification was performed by observation of morphologic and biochemical characteristics and sequencing of the internal transcribed spacers (its) 1 and 2. treatment with oral terbinafine and topical naftifine-ketoconazole cream after washing the hair with ketoconazole shampoo was effective.201120662636
a case of kerion celsi caused by microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident.we report a rare case of kerion celsi of the scalp caused by microsporum gypseum in a boy 1 month after he received dermatoplasty for a scalp injury from a road accident. species identification was performed by observation of morphologic and biochemical characteristics and sequencing of the internal transcribed spacers (its) 1 and 2. treatment with oral terbinafine and topical naftifine-ketoconazole cream after washing the hair with ketoconazole shampoo was effective.201120662636
preparation and evaluation of dermal delivery system of griseofulvin containing vitamin e-tpgs as penetration enhancer.griseofulvin, an antifungal agent, is a bcs class ii drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. the clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter- and intra-subject variation in bioavailability from different commercial products. moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. the purp ...201122130790
preparation and evaluation of dermal delivery system of griseofulvin containing vitamin e-tpgs as penetration enhancer.griseofulvin, an antifungal agent, is a bcs class ii drug slowly, erratically, and incompletely absorbed from the gastrointestinal tract in humans. the clinical failure of the conventional oral therapy of griseofulvin is most likely attributed to its poor solubility and appreciable inter- and intra-subject variation in bioavailability from different commercial products. moreover, the conventional oral therapy is associated with numerous adverse effects and interactions with other drugs. the purp ...201122130790
Difference in keratinase activity of dermatophytes at different environmental conditions is an attribute of adaptation to parasitism.Dermatophytes are a group of morphologically and physiologically related moulds, which cause well-defined infection called dermatophytosis. The enzymatic ability of fungi to decompose keratin has long been interpreted as a key innovation in the evolution of animal dermatology. In the present study, keratinase activity profile among Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis and Microsporum gypseum isolated on keratin substrates such as human hair, human nail and chicken ...201122032519
Difference in keratinase activity of dermatophytes at different environmental conditions is an attribute of adaptation to parasitism.Dermatophytes are a group of morphologically and physiologically related moulds, which cause well-defined infection called dermatophytosis. The enzymatic ability of fungi to decompose keratin has long been interpreted as a key innovation in the evolution of animal dermatology. In the present study, keratinase activity profile among Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis and Microsporum gypseum isolated on keratin substrates such as human hair, human nail and chicken ...201122032519
anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of rhamnus catharticus and r. orbiculatus.the anthraquinone profile, antioxidant and antimicrobial activities as well as the total phenol and total flavonoid contents were determined in methanol extracts of the barks of rhamnus catharticus l. and r. orbiculatus bornm. the most abundant anthraquinone derivatives in r. catharticus were physcion (67.8%) and emodin (26.2%), while r. orbiculatus contained mostly physcion (81.3%) and chrysophanol (14.6%). r. catharticus displayed better activity in the beta-carotene-linoleic acid assay, as we ...201121941897
anthraquinone profile, antioxidant and antimicrobial properties of bark extracts of rhamnus catharticus and r. orbiculatus.the anthraquinone profile, antioxidant and antimicrobial activities as well as the total phenol and total flavonoid contents were determined in methanol extracts of the barks of rhamnus catharticus l. and r. orbiculatus bornm. the most abundant anthraquinone derivatives in r. catharticus were physcion (67.8%) and emodin (26.2%), while r. orbiculatus contained mostly physcion (81.3%) and chrysophanol (14.6%). r. catharticus displayed better activity in the beta-carotene-linoleic acid assay, as we ...201121941897
mating genes of the trichophyton mentagrophytes complex.the mating type (-)-specific gene of the alpha-box and the mating type (+)-specific gene of the high-mobility group (hmg) dna-binding domain were confirmed in zoophilic dematophytes of arthroderma simii and a. vanbreuseghemii. the sequence of the alpha-box gene was 1,375 bp, containing 2 exons (from 172 to 463 bp and from 513 to 1,375 bp) in the a. simii (-) mating type strain and 1,380 bp, containing 2 exons (from 177 to 468 bp and from 518 to 1,380 bp) in the a. vanbreuseghemii (-) mating type ...201122057847
mating genes of the trichophyton mentagrophytes complex.the mating type (-)-specific gene of the alpha-box and the mating type (+)-specific gene of the high-mobility group (hmg) dna-binding domain were confirmed in zoophilic dematophytes of arthroderma simii and a. vanbreuseghemii. the sequence of the alpha-box gene was 1,375 bp, containing 2 exons (from 172 to 463 bp and from 513 to 1,375 bp) in the a. simii (-) mating type strain and 1,380 bp, containing 2 exons (from 177 to 468 bp and from 518 to 1,380 bp) in the a. vanbreuseghemii (-) mating type ...201122057847
Broad spectrum antidermatophytic drug for the control of tinea infection in human beings.During antifungal evaluation of various plant extracts, free and bound flavonoids of Piper betle were found to be most effective as an antidermatophytic against human pathogenic dermatophytes Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum gypseum and Candida albicans. Dermatophytic fungi cause both superficial and internal mycoses. These mycoses, although normally not lethal, are unpleasant and difficult to cure and cause considerable financial losses. Earlier workers prove that a ...201121929713
Broad spectrum antidermatophytic drug for the control of tinea infection in human beings.During antifungal evaluation of various plant extracts, free and bound flavonoids of Piper betle were found to be most effective as an antidermatophytic against human pathogenic dermatophytes Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum gypseum and Candida albicans. Dermatophytic fungi cause both superficial and internal mycoses. These mycoses, although normally not lethal, are unpleasant and difficult to cure and cause considerable financial losses. Earlier workers prove that a ...201121929713
Antifungal activity and chemical composition of essential oils from Smyrnium olusatrum L. (Apiaceae) from Italy and Portugal.The essential oils and supercritical CO(2) extracts of wild Smyrnium olusatrum L. growing in Sardinia (Italy) and in Portugal were investigated. For the study, oils were isolated from total plant aerial part (umbels containing seeds). The content of ß-phellandrene (67.3% vs. 42.7%) and a-pinene (31.9% vs. 1.2%), respectively, the main components of Portuguese and Italian essential oils, declined during the maturation stage of the umbels. Contrarily, some other important components, particularly ...201121902563
Antifungal activity and chemical composition of essential oils from Smyrnium olusatrum L. (Apiaceae) from Italy and Portugal.The essential oils and supercritical CO(2) extracts of wild Smyrnium olusatrum L. growing in Sardinia (Italy) and in Portugal were investigated. For the study, oils were isolated from total plant aerial part (umbels containing seeds). The content of ß-phellandrene (67.3% vs. 42.7%) and a-pinene (31.9% vs. 1.2%), respectively, the main components of Portuguese and Italian essential oils, declined during the maturation stage of the umbels. Contrarily, some other important components, particularly ...201121902563
Assessment of antimicrobial, insecticidal and genotoxic effects of Melia azedarach L. (chinaberry) naturalized in Anatolia.In this study, antibacterial, antifungal, insecticidal and genotoxic activities of the fruit and leaf extracts of Melia azedarach of Turkish origin were evaluated for the first time. The antimicrobial activity was assessed against Gram (+) and ( - ) bacteria, four Candida species and three dermatophytic fungus (Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum). The insecticidal activity of the methanolic fruit extract was performed against the larvae of Aedes aegpyti, Culex ...201122149768
Assessment of antimicrobial, insecticidal and genotoxic effects of Melia azedarach L. (chinaberry) naturalized in Anatolia.In this study, antibacterial, antifungal, insecticidal and genotoxic activities of the fruit and leaf extracts of Melia azedarach of Turkish origin were evaluated for the first time. The antimicrobial activity was assessed against Gram (+) and ( - ) bacteria, four Candida species and three dermatophytic fungus (Trichophyton rubrum, Epidermophyton floccosum and Microsporum gypseum). The insecticidal activity of the methanolic fruit extract was performed against the larvae of Aedes aegpyti, Culex ...201122149768
design, synthesis and antifungal activity of some new imidazole and triazole derivatives.triazole and imidazole are incorporated into the structures of many antifungal compounds. in this study a novel series of 1,2,4-triazole, imidazole, benzoimidazole, and benzotriazole derivatives was designed as inhibitors of cytochrome p450 14α-demethylase (14dm). these structures were docked into the active site of mt-cyp51, using autodock program. sixteen compounds with the best binding energy were synthesized. the chemical structures of the new compounds were confirmed by elemental and spectr ...201121984016
design, synthesis and antifungal activity of some new imidazole and triazole derivatives.triazole and imidazole are incorporated into the structures of many antifungal compounds. in this study a novel series of 1,2,4-triazole, imidazole, benzoimidazole, and benzotriazole derivatives was designed as inhibitors of cytochrome p450 14α-demethylase (14dm). these structures were docked into the active site of mt-cyp51, using autodock program. sixteen compounds with the best binding energy were synthesized. the chemical structures of the new compounds were confirmed by elemental and spectr ...201121984016
chemical and biological diversity in fourteen selections of four ocimum species.biomass, essential oil yield, essential oil composition diversity, and antibacterial and antifungal activities of 14 selections of 4 ocimum species [ocimum basilicum l. (selections: t1-t10), o. gratissimum l. (selections: t11-t12), o. tenuiflorum l.f., syn. o. sanctum l. (selection: t13) and o. kilimandscharicum baker ex. guerke (selection: t14)] were investigated. o. basilicum selections t9 (methyl chavicol: 87.0%) and t10 {(z)- and (e)-methyl cinnamate: 69.1%} produced higher biomass (67.8 and ...201122224293
chemical and biological diversity in fourteen selections of four ocimum species.biomass, essential oil yield, essential oil composition diversity, and antibacterial and antifungal activities of 14 selections of 4 ocimum species [ocimum basilicum l. (selections: t1-t10), o. gratissimum l. (selections: t11-t12), o. tenuiflorum l.f., syn. o. sanctum l. (selection: t13) and o. kilimandscharicum baker ex. guerke (selection: t14)] were investigated. o. basilicum selections t9 (methyl chavicol: 87.0%) and t10 {(z)- and (e)-methyl cinnamate: 69.1%} produced higher biomass (67.8 and ...201122224293
bioactive constituents of homalomena aromatica essential oil and its antifungal activity against dermatophytes and yeasts.homalomena aromatica rhizomes are rich source of essential oils, which have been attributed for various medicinal uses. in the present investigation, essential oil from h. aromatica rhizomes was isolated and subjected to gas chromatography-mass spectrum (gc-ms) analysis. fifty-five chemical constituents were reported from h. aromatica rhizomes of which t-muurolol (5.32%), viridiflorol (3.69%), α-selinene (2.19%), m-cymene (2.19%) and γ-muurolene (1.81%) were identified and reported for the first ...201123177818
bioactive constituents of homalomena aromatica essential oil and its antifungal activity against dermatophytes and yeasts.homalomena aromatica rhizomes are rich source of essential oils, which have been attributed for various medicinal uses. in the present investigation, essential oil from h. aromatica rhizomes was isolated and subjected to gas chromatography-mass spectrum (gc-ms) analysis. fifty-five chemical constituents were reported from h. aromatica rhizomes of which t-muurolol (5.32%), viridiflorol (3.69%), α-selinene (2.19%), m-cymene (2.19%) and γ-muurolene (1.81%) were identified and reported for the first ...201123177818
isolation of keratinophilic fungi from soil in isfahan province, iran.to evaluate the epidemiology of keratophilic fungi in isfahan province, iran.201123177808
isolation of keratinophilic fungi from soil in isfahan province, iran.to evaluate the epidemiology of keratophilic fungi in isfahan province, iran.201123177808
in vitro microbiological evaluation of 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones, novel bisacetylated pyrazoles.novel 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones 7-12 were tested for their antimicrobial activity by disc diffusion and twofold serial dilution method against the tested bacterial and fungal strains. compounds 7 against micrococcus luteus, 8 against β-heamolytic streptococcus, m. luteus, klebsiella pneumonia, microsporum gypseum, 9 against staphylococcus aureus, shigella flexneri, vibreo cholerae, pseudomonas aeruginosa, aspergillus flavus, mucor indicus, 10 ...201122373408
in vitro microbiological evaluation of 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones, novel bisacetylated pyrazoles.novel 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1h-pyrazole-5,1-(4h,5h)-diyl))diethanones 7-12 were tested for their antimicrobial activity by disc diffusion and twofold serial dilution method against the tested bacterial and fungal strains. compounds 7 against micrococcus luteus, 8 against β-heamolytic streptococcus, m. luteus, klebsiella pneumonia, microsporum gypseum, 9 against staphylococcus aureus, shigella flexneri, vibreo cholerae, pseudomonas aeruginosa, aspergillus flavus, mucor indicus, 10 ...201122373408
antifungal activity of aegle marmelos (l.) correa (rutaceae) leaf extract on dermatophytes.to evaluate the in vitro antifungal activity of aegle marmelos leaf extracts and fractions on the clinical isolates of dermatophytic fungi like trichophyton mentagrophytes, trichophyton rubrum, microsporum canis, microsporum gypseum and epidermophyton floccosum.201123569781
antifungal activity of aegle marmelos (l.) correa (rutaceae) leaf extract on dermatophytes.to evaluate the in vitro antifungal activity of aegle marmelos leaf extracts and fractions on the clinical isolates of dermatophytic fungi like trichophyton mentagrophytes, trichophyton rubrum, microsporum canis, microsporum gypseum and epidermophyton floccosum.201123569781
anti-dermatophytic activity of marine sponge, sigmadocia carnosa (dendy) on clinically isolated fungi.to screen the anti-fungal effects and find out the active metabolites from sponge, sigmadocia carnosa (s. carnosa) against four dermatophytic fungi.201223569985
anti-dermatophytic activity of marine sponge, sigmadocia carnosa (dendy) on clinically isolated fungi.to screen the anti-fungal effects and find out the active metabolites from sponge, sigmadocia carnosa (s. carnosa) against four dermatophytic fungi.201223569985
chemical composition and antifungal activity of matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens.fungal infections are potential public health threats all over the world. in the present study, effect of matricaria recutita flower essential oil (eo) was evaluated against medically important dermatophytes and opportunistic saprophytes using microbioassay technique.201223518164
chemical composition and antifungal activity of matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens.fungal infections are potential public health threats all over the world. in the present study, effect of matricaria recutita flower essential oil (eo) was evaluated against medically important dermatophytes and opportunistic saprophytes using microbioassay technique.201223518164
synthesis, in vitro antifungal evaluation and in silico study of 3-azolyl-4-chromanone phenylhydrazones. 201223351328
synthesis, in vitro antifungal evaluation and in silico study of 3-azolyl-4-chromanone phenylhydrazones. 201223351328
epidemiological investigation of keratinophilic fungi from soils of djerba (tunisia).epidemiological investigation of keratinophilic fungi in soil has been carried out in different parts of the world. however, our knowledge of the present occurrence and distribution of keratinophilic fungi in tunisian soils remains unknown. this study was carried out to evaluate the epidemiological characteristics of keratinophilic fungi in the soils collected in djerba (south of tunisia).201223518079
epidemiological investigation of keratinophilic fungi from soils of djerba (tunisia).epidemiological investigation of keratinophilic fungi in soil has been carried out in different parts of the world. however, our knowledge of the present occurrence and distribution of keratinophilic fungi in tunisian soils remains unknown. this study was carried out to evaluate the epidemiological characteristics of keratinophilic fungi in the soils collected in djerba (south of tunisia).201223518079
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