Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| comparative in vivo adulticidal activity of a topical dinotefuran versus an imidacloprid-based formulation against cat fleas (ctenocephalides felis) on cats. | fleas cause significant discomfort to pet cats and distress to their owners and are also vectors of disease severe infestations can cause anemia or flea allergy dermatitis and can lead to infections with dipylidium caninum and bartonella henselae. rapid flea kill is an important feature of flea preventives. the efficacy of dinotefuran (vectra for cats and kittens, summit vetpharm) was compared with that of imidacloprid (advantage, bayer animal health) against ctenocephalides felis when applied t ... | 2009 | 19742443 |
| rapid detection of bartonella henselae heat shock protein dna by nested polymerase chain reaction from swollen lymph nodes of a patient with cat-scratch disease. | 2009 | 19785710 | |
| cat scratch disease: a diagnostic conundrum. | we report the case of a patient who presented to a clinic for evaluation of inguinal lymphadenopathy. histology of the lymph nodes revealed micoabscess formation suggesting infection with lymphogranuloma venereum (lgv) or bartonella henselae--the causative agent in cat scratch disease (csd). the patient recalled no preceding animal exposure. clinical and serological findings initially suggested early lgv but convalescent serology supported csd. this serves as an important reminder that b. hensel ... | 2009 | 19625597 |
| diffusion-weighted magnetic resonance imaging in cervical lymphadenopathy: report of three cases of patients with bartonella henselae infection mimicking malignant disease. | diffusion-weighted mr imaging is a potential technique for differentiation between benign and malignant lymph nodes. however, lympadenopathy caused by bartonella henselae infection showes low adc values in diffusion weighted mri as typically seen in malignant disease. | 2009 | 19636985 |
| cat scratch disease with cervical vertebral osteomyelitis and spinal epidural abscess. | cat scratch disease has variable clinical presentations and should be considered in the differential diagnosis of vertebral osteomyelitis and epidural abscess if there is a history of contact with cats. we report a 5-year-old boy with cat scratch disease who presented with painful torticollis and osteomyelitis of the cervical spine associated with an epidural abscess. | 2009 | 19654566 |
| cervical lymphadenopathy in childhood epidemiology and management. | cervical lymphadenopathy (cl) is common in childhood. the aim of this study is to evaluate the etiology, follow-up, and treatment of persistent cl. the authors studied retrospectively 50 children with cl, hospitalized at the department of pediatrics and pediatrics surgery. patients underwent ultrasonography. thirty-six percent presented abnormal ultrasonographic image and underwent excisional biopsy. biopsies revealed 4 thyroglossal cysts, 3 branchial cysts, 1 hemangioma, 2 sebaceous cysts, 1 de ... | 2009 | 19657996 |
| [cat scratch disease--a diagnostic problem, case report]. | cat scratch disease as a possible cause of neck limphadenopathy. | 2009 | 19681487 |
| real-time pcr strategy and detection of bacterial agents of lymphadenitis. | the aim of this study was to compare 16 s rrna gene amplification and sequencing with a systematic real-time pcr assay screening strategy that includes all common known pathogens recovered from lymph node biopsy specimens. lymph node biopsy samples sent to our laboratory from january 2007 to december 2008 were tested in the study. lymph nodes were screened for the presence of any bacteria by pcr amplification and sequencing targeting the 16 s rrna gene and also by a specific real-time pcr strate ... | 2009 | 19685089 |
| genomics of host-restricted pathogens of the genus bartonella. | the alpha-proteobacterial genus bartonella comprises numerous arthropod-borne pathogens that share a common host-restricted life-style, which is characterized by long-lasting intraerythrocytic infections in their specific mammalian reservoirs and transmission by blood-sucking arthropods. infection of an incidental host (e.g. humans by a zoonotic species) may cause disease in the absence of intra-erythrocytic infection. the genome sequences of four bartonella species are known, i.e. those of the ... | 2009 | 19696500 |
| [infective endocarditis due to bartonella henselae following a rupture of a cerebral aneurysm]. | we report a case of severe aortic bicuspid valve endocarditis, revealed by global cardiac failure without fever, in a 38-year-old man who had developed cerebral mycotic aneurysms nine months earlier. pcr analysis of the excised aortic valve and serological tests (even 9 months earlier) were positive for bartonella henselae. a combination of intravenous then oral doxycyclin at 200mg/day and intravenous gentamycin at 90mg/day was given for 6 and 2 weeks respectively. the evolution was favorable on ... | 2009 | 19097835 |
| isolation of candidatus bartonella melophagi from human blood. | candidatus bartonella melophagi was isolated by blood culture from 2 women, 1 of whom was co-infected with b. henselae. partial 16s rrna, rna polymerase b, and citrate synthase genes and 16s-23s internal transcribed spacer sequences indicated that human isolates were similar to candidatus b. melophagi. | 2009 | 19116054 |
| evaluation of immunohistochemistry in identifying bartonella henselae in cat-scratch disease. | cat-scratch disease (csd) is largely due to infection with bartonella henselae. microbiologic detection is difficult, and molecular testing is not readily available. a monoclonal antibody (mab) to b henselae has become commercially available. we evaluated the usefulness of immunohistochemical analysis (ihc) for diagnosing csd on surgical specimens and compared these results with polymerase chain reaction (pcr) detection and serologic testing for b henselae. we studied 24 formalin-fixed, paraffin ... | 2009 | 19141385 |
| delayed exposure to infections and childhood lymphomas: a case-control study. | delayed exposure to common infections during childhood, have been implied to cause strong immunological response to a single infectious agent that eventually triggers leukemogenesis. the aim of the present study was to investigate whether decreased exposure to infections, as reflected in a more seronegative spectrum to several common infectious agents, is associated with increased risk for the development of childhood lymphomas. | 2009 | 19169895 |
| isolation or molecular detection of bartonella henselae and bartonella vinsonii subsp. berkhoffii from dogs with idiopathic cavitary effusions. | 2009 | 19175739 | |
| back pain in a child caused by cat scratch disease. | 2009 | 19209087 | |
| distinct activities of bartonella henselae type iv secretion effector proteins modulate capillary-like sprout formation. | the zoonotic pathogen bartonella henselae (bh) can lead to vasoproliferative tumour lesions in the skin and inner organs known as bacillary angiomatosis and bacillary peliosis. the knowledge on the molecular and cellular mechanisms involved in this pathogen-triggered angiogenic process is confined by the lack of a suitable animal model and a physiologically relevant cell culture model of angiogenesis. here we employed a three-dimensional in vitro angiogenesis assay of collagen gel-embedded endot ... | 2009 | 19416269 |
| clinical aspects of bartonella infection in northern greece. | 2009 | 19456804 | |
| description of bartonella spp. infections in a general hospital of catalonia, spain. | 2009 | 19456816 | |
| immunogenicity of bartonella henselae p26 in cats. | cat scratch disease (csd) has an estimated prevalence of approximately 200,000 persons in the usa, and approximately 22,000 new cases occur annually. cats are the natural carriers of bartonella henselae, the agent for csd. zoonotic transmission of b. henselae can result in csd in immunocompetent humans and bacillary angiomatosis in immunosuppressed humans. infection in cats often goes undetected. development of a vaccine to prevent feline infection is warranted to reduce the prevalence of infect ... | 2009 | 19500857 |
| plasmid-based system for high-level gene expression and antisense gene knockdown in bartonella henselae. | six broad-host-range plasmid vectors were developed to study gene expression in bartonella henselae. the vectors were used to express a beta-galactosidase reporter gene in b. henselae and to generate antisense rna for gene knockdown. when applied to ompr, a putative transcription response regulator of b. henselae, this antisense rna gene knockdown strategy reduced bacterial invasion of human endothelial cells by over 60%. | 2009 | 19542333 |
| duplex pcr assay simultaneously detecting and differentiating bartonella quintana, b. henselae, and coxiella burnetii in surgical heart valve specimens. | a duplex pcr (dpcr) assay was developed to simultaneously detect and differentiate bartonella quintana, bartonella henselae, and coxiella burnetii from surgical heart valve tissue specimens with an analytic sensitivity of 10 copies/reaction. among 17 specimens collected from patients with a clinical diagnosis of culture-negative endocarditis, 2, 4, and 2 were positive for b. quintana, b. henselae, and c. burnetii, respectively, by the dpcr assay, which matched the results obtained by universal b ... | 2009 | 19553582 |
| computed tomography and magnetic resonance imaging of cat-scratch disease: a report of two cases. | cat-scratch disease (csd) is a bacterial infection that typically causes swelling of the lymph nodes. the patients usually have a history of being scratched, bitten, or licked by cats and often by kittens. understanding the characteristic radiological and clinical features may lead to a noninvasive diagnosis and prevent unnecessary invasive procedures. we report two cases of csd with computed tomography and magnetic resonance imaging showing nodules or masses of lymphadenopathy with subcutaneous ... | 2009 | 19559357 |
| co-isolation of bartonella henselae and bartonella vinsonii subsp. berkhoffii from blood, joint and subcutaneous seroma fluids from two naturally infected dogs. | this report describes the clinical presentation, isolation and treatment of two dogs naturally infected with bartonella henselae and bartonella vinsonii subsp. berkhoffii. chronic and progressive polyarthritis was the primary complaint for dog #1, from which b. henselae and b. vinsonii subsp. berkhoffii were cultured on three independent occasions from blood and joint fluid samples, despite administration of nearly 4 months of non-consecutive antibiotic therapy. a clinically atypical and progres ... | 2009 | 19560291 |
| disseminated infection with bartonella henselae in a lung transplant recipient. | we present the case of a lung transplant recipient with disseminated infection with bartonella henselae. in non-immunosuppressed humans, the organism typically causes a local infection that manifests itself as regional lymphadenopathy. the role of the host immune response to b henselae is critical in preventing progression to systemic disease. only rare cases of bartonellosis in transplant recipients have been reported. we discuss aspects and difficulties of diagnosis and treatment of bartonello ... | 2009 | 19560704 |
| the bacteriology of salivary gland infections. | the parotid gland is the salivary gland most commonly affected by inflammation. however, infection of the salivary glands can occur in any of the glands. the most common pathogens associated with acute bacterial infection are staphylococcus aureus and anaerobic bacteria. the predominant anaerobes include: anaerobic gram negative bacilli (eg, pigmented prevotella and porphyromonas); fusobacterium spp; and peptostreptococcus spp. in addition, streptococcus spp (including streptococcus pneumoniae) ... | 2009 | 19608044 |
| bartonellosis causing bilateral leber neuroretinitis: a case report. | bartonella henselae is the causal agent of cat scratch disease and one variation in its presentation is leber neuroretinitis. the unilateral presence of exudation as a macular star and papilledema represent its most common presentation. | 2009 | 19253255 |
| prevalence of bartonella henselae and bartonella clarridgeiae in cats and dogs in korea. | blood, saliva, and nail samples were collected from 54 dogs and 151 cats and analyzed for the presence of bartonella henselae with a novel nested polymerase chain reaction (pcr) method. bartonella (b.) henselae was detected in feral cat blood (41.8%), saliva (44.1%), and nail (42.7%) samples. b. henselae was also detected in pet cat blood (33.3%), saliva (43.5%), and nail (29.5%) samples and in pet dog blood (16.6%), saliva (18.5%), and nail (29.6%) samples. nine samples were infected with b. cl ... | 2009 | 19255530 |
| [clinical thinking and decision making in practice. a man with abdominal pain, weight loss and fever]. | 2009 | 19256242 | |
| identification of bartonella henselae in an aborted equine fetus. | this report describes the characterization of a bartonella henselae abortion in an equine fetus by gross, histologic, immunohistochemical, ultrastructural, and molecular methods. bartonella henselae can cause cat scratch disease, bacillary angiomatosis, bacillary peliosis, and endocarditis in humans and other animals. the bacterium has been isolated from several mammalian species but only recently from equids; however, it has not been linked to abortion in equids. an aborted equine fetus exhibit ... | 2009 | 19261640 |
| prevalence of bartonella henselae antibodies in children and blood donors in croatia. | 2009 | 19274430 | |
| ecological fitness and strategies of adaptation of bartonella species to their hosts and vectors. | bartonella spp. are facultative intracellular bacteria that cause characteristic hostrestricted hemotropic infections in mammals and are typically transmitted by blood-sucking arthropods. in the mammalian reservoir, these bacteria initially infect a yet unrecognized primary niche, which seeds organisms into the blood stream leading to the establishment of a long-lasting intra-erythrocytic bacteremia as the hall-mark of infection. bacterial type iv secretion systems, which are supra-molecular tra ... | 2009 | 19284965 |
| bacillary angiomatosis. | an infection with bartonella henselae transmitted from domestic cats to humans by scratching normally leads to cat-scratch disease. when the human host has severe immunosuppression or hiv infection, the potentially life-threatening disease bacillary angiomatosis can develop. a 79-year-old man presented with livid-erythematous, angioma-like skin lesions. we considered a cutaneous infiltrate from his known chronic lymphocytic leukemia, merkel cell carcinoma, cutaneous metastases of internal tumors ... | 2009 | 19298547 |
| a translocated protein of bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome. | bartonella henselae enters human endothelial cells (ecs) by two alternative routes: either by endocytosis, giving rise to bartonella-containing vacuoles or by invasome-mediated internalization. only the latter process depends on the type iv secretion system virb/vird4 and involves the formation of cell surface-associated bacterial aggregates, which get engulfed by ec membranes in an f-actin-dependent manner, eventually resulting in their complete internalization. here, we report that among the v ... | 2009 | 19302579 |
| [cat scratch disease with bone involvement: a case report and literature review]. | cat scratch disease is an infectious disease caused by bartonella henselae. most of the patients present with a lymphadenopathy associated with a local infection at the site of the cat scratch. disseminated infection is uncommon. | 2009 | 19303175 |
| cat scratch disease: clinical considerations for the pediatric dentist. | cat scratch disease (csd), caused by bartonella henselae, is a self-limited chronic lymphadenopathy. it is transmitted commonly by a scratch or bite from cats or kittens. diagnosis of csd is often difficult, as it masquerades as other causes of cervical lymphadenopathy or submandibular gland pathology. the purpose of this paper was to report a unique case of a 6-year old male who had close contact with a domestic dog and developed csd which progressed to suppuration. after treatment with antibio ... | 2009 | 19320261 |
| proteomic analysis of the bacterial pathogen bartonella henselae and identification of immunogenic proteins for serodiagnosis. | bartonella henselae is a slow growing, fastidious and facultative intracellular pathogen causing cat scratch disease and vasculoproliferative disorders. to date, knowledge about the pathogenicity of this human pathogenic bacterium is limited and, additionally, serodiagnosis still needs further improvement. here, we investigated the proteome of b. henselae using 2-d sds-page and maldi-tof-ms. we provide a comprehensive 2-d proteome reference map of the whole cell lysate of b. henselae with 431 id ... | 2009 | 19333998 |
| experimental infection of cats with bartonella henselae resulted in rapid clearance associated with t helper 1 immune responses. | six cats were inoculated with bartonella henselae strains a and b, which were isolated from the same naturally infected cat. the numbers of cd4(+) cells decreased following the infection. the levels of bacteremia were significantly correlated with the expression levels of ifn-gamma mrna during the various stages of bacteremia and elimination of the bacteremia. furthermore, the lower levels of tnf-alpha mrna expression during the bacteremia related to the emergence of higher levels of bacteremia. ... | 2009 | 19348961 |
| molecular characterization of resistance to fluoroquinolones in bartonella henselae and bartonella quintana. | 2009 | 19369272 | |
| prevalence of bartonella infection in cats and dogs in a metropolitan area, thailand. | the prevalence of bartonella infection was studied in 312 cats and 350 dogs in the bangkok metropolitan areas, thailand, between june 2001 and february 2003. bartonella was isolated from 47 (16.3%) of 288 stray cats, but from none of the 24 pet cats studied. of the 47 bartonella-positive cats, 45 animals were infected with only b. henselae, one was infected with only b. clarridgeiae, and one with both b. henselae and b. clarridgeiae. 16s rrna typing showed that 40 cats were infected with b. hens ... | 2009 | 19379541 |
| [positive polymerase chain reaction for bartonella henselae in conjunctival granuloma]. | 2009 | 19384797 | |
| identification of a bartonella species in the harbor seal (phoca vitulina) and in seal lice (echinophtirius horridus). | to explore whether harbor seals (phoca vitulina) are exposed to bartonella spp., 35 seal lice (echinophtirius horridus) were collected from seven seals, during their rehabilitation period in the seal rehabilitation and research center at pieterburen, the netherlands. forty-eight spleen samples were collected during necropsies of other harbor seals that died during rehabilitation, or had stranded dead and were brought to the seal rehabilitation and research center for postmortem investigation. li ... | 2009 | 19402763 |
| molecular epidemiology of feline and human bartonella henselae isolates. | multiple locus variable number tandem repeat analysis was performed on 178 bartonella henselae isolates from 9 countries; 99 profiles were distributed into 2 groups. human isolates/strains were placed into the second group. genotype i and ii isolates shared no common profile. all genotype i isolates clustered within group b. the evolutive implications are discussed. | 2009 | 19402978 |
| cat scratch disease presenting with a retroperitoneal abscess in a patient without animal contacts. | cat scratch disease (csd) is usually diagnosed in patients presenting with regional lymphadenopathy and pyrexia that follow contacts with animals. we describe here a young adult male patient who presented with marked pyrexia and a retroperitoneal abscess without relevant medical histories, illustrating that csd can be a diagnostic challenge on selected occasions. | 2009 | 20012734 |
| color doppler pseudolymphomatous manifestations of the cat scratch disease. | cat scratch disease (csd) is an infectious illness, caused by the bartonella henselae bacterium. besides the common infective symptoms, swelling in the axillary and cervical region is very common and is usually evaluated by color doppler us (cdus) (among other diagnostic methods). the aim of this work is to present ultrasound findings of the cat scratch disease. during 2002 and 2003, we followed four patients (three male and one female) by cdus, with different manifestations of the disease. the ... | 2009 | 20380135 |
| serous labyrinthitis as a manifestation of cat scratch disease: a case report. | abstract : introduction : cat scratch disease is an infectious disease transmitted by young cats, in which the principal causative factor is bartonella henselae. the typical course of cat scratch disease is usually benign and self-limited and requires only supportive therapy. however, cases lasting up to 2 years have been reported, and more serious complications may occur. many manifestations of the disease have been reported by different medical disciplines. case presentation : a case of cat sc ... | 2009 | 20519021 |
| molecular mechanism of gentamicin resistance in bartonella henselae. | 2009 | 20584166 | |
| bartonella endocarditis complicating congenital heart disease. | the present report describes a case of bartonella henselae endocarditis affecting an adolescent with congenital heart disease. a teenager from eastern europe was referred to for surgical treatment of aortic endocarditis. she admitted close contact with cats. blood culture was negative. diagnosis of b henselae was established on direct pcr amplification and 16srrna gene sequencing of the aortic valve tissue and confirmed after 4 weeks by valve culture isolate. the patient underwent extended root ... | 2009 | 21686936 |
| evaluation of an in-house cat scratch disease igm elisa to detect bartonella henselae in a routine laboratory setting. | cat scratch disease (csd) is caused by bartonella henselae infection and is a common cause of regional lymphadenopathy. the diagnosis of csd largely depends on serology, but detection of b. henselae in an affected lymph node by pcr is also an important diagnostic tool. we evaluated an igm in-house elisa protocol and analyzed its performance in routine csd serology. serum samples from pcr-positive patients (n = 126), pcr-negative patients (n = 123), and age-matched controls (n = 126) were used fo ... | 2009 | 18679728 |
| investigation of bartonella henselae in cats in ankara, turkey. | the purpose of this study was to determine bartonella henselae prevalance in cats in ankara. whole bloods and sera collected from 256 cats were investigated for the presence feline bartonella species by culture and sera were tested for the presence of antibodies against b. henselae igg using immunofluorescence assay. bartonella species were isolated by blood culture from 24 (9.4%) cats. bartonella isolates were subjected to restriction fragment length polymorphism (rflp) by using taqi and hhai e ... | 2009 | 18990198 |
| bartonella henselae: subversion of vascular endothelial cell functions by translocated bacterial effector proteins. | bartonella henselae (bh) is a worldwide distributed zoonotic pathogen. depending on the immune status of the infected individual this bacterium can cause a wide spectrum of clinical manifestations, ranging from cat scratch disease (csd) to bacillary angiomatosis (ba) and bacillary peliosis (bp). ba and bp are characterized by tumor-like lesions at the skin or in the inner organs, respectively. these structures display pathological sprouting of capillaries with enlarged and hyperproliferated vasc ... | 2009 | 19010441 |
| pcr detection of bartonella bovis and bartonella henselae in the blood of beef cattle. | although an organism primarily associated with non-clinical bacteremia in domestic cattle and wild ruminants, bartonella bovis was recently defined as a cause of bovine endocarditis. the purpose of this study was to develop a b. bovis species-specific pcr assay that could be used to confirm the molecular prevalence of bartonella spp. infection. blood samples from 142 cattle were tested by conventional pcr targeting the bartonella 16s-23s intergenic spacer (its) region. overall, bartonella dna wa ... | 2009 | 19019574 |
| prevalence of bartonella species antibodies and bartonella species dna in the blood of cats with and without fever. | the purpose of this study was to determine whether there are associations between bartonella species antibody (enzyme-linked immunosorbent assay (elisa) and western blot (wb)) and polymerase chain reaction assay results in cats with and without fever. afebrile control cats (39/93; 42.0%) were more likely to have bartonella species antibodies than cats with fever (29/93; 31.2%). the difference in prevalence of bartonella species deoxyribonucleic acid (dna) in blood of cats with fever (14/81; 17.3 ... | 2009 | 18760647 |
| neuroretinitis associated with serologies positive for bartonella henselae and borrelia burgdorferi. | to describe a patient with neuroretinitis with features of both cat-scratch disease and lyme disease who had serologies positive for both bartonella henselae and borrelia burgdorferi. | 2009 | 25389574 |
| cat scratch disease: a diagnostic dilemma. | cat scratch disease (csd) caused by bartonella henselae is the most common bartonella infection worldwide. csd usually presents as self-limiting lymphadenitis characterized by lymphadenopathy that occurs after contact with a cat and the symptoms resolve within 2 to 4 months. serology testing is the cornerstone of diagnosis. however, it may require the use of clinical specimens for microbiologic evaluation for diagnosis. a number of antimicrobial agents have been advocated for the treatment of ca ... | 2010 | 23756805 |
| detection of bartonella henselae in domestic cats' saliva. | bartonella species are being recognized as increasingly important bacterial pathogens in veterinary and human medicine. these organisms can be transmitted by an arthropod vector or alternatively by animal scratches or bites. the objectives of this study were to identify contamination of cat's saliva and nail with b. henselae as a causative role to infect human in a sample of the cat population in iran. | 2010 | 22347553 |
| bartonella henselae aortic valve endocarditis mimicking systemic vasculitis. | a 28-year-old man with a bicuspid aortic valve presented with facial droop and slurred speech with several months of constitutional symptoms of night sweats, weight loss and productive cough. examination confirmed aortic regurgitation, palpable spleen and left facial droop. multiple peripheral blood cultures were negative. inflammatory markers, cytoplasmic staining antineutrophil cytoplasmic antibodies (canca) and anti-pr3 antibody were all elevated. mri of the brain and ct of the chest and abdo ... | 2010 | 22791485 |
| optic neuropathy secondary to cat scratch disease: case report. | optic neuropathy due to cat scratch disease is a relatively infrequent occurrence associated with macular star formation and is characterized by sudden painless loss of vision mostly unilateral. bartonella henselae is well recognized as the etiologic agent in cat scratch disease. ocular complications of the disease occur in up to 10% of patients and include neuroretinitis. ocular bartonelosis is usually self-limited with complete or near-complete recovery of vision in otherwise healthy patients. ... | 2010 | 21271032 |
| association between bartonella species infection and disease in pet cats as determined using serology and culture. | this study's objective was to determine whether a relationship exists between infection or seropositivity to bartonella species and clinical illness in cats. blood samples were obtained for bartonella species isolation and immunofluorescent antibody serology from 298 cats presenting to a tertiary referral hospital. medical records were searched and the history, physical examination findings and the results of diagnostic testing relating to the visit at which bartonella species testing was perfor ... | 2010 | 20570199 |
| expressive aphasia as a presentation of encephalitis with bartonella henselae infection in an immunocompetent adult. | to show the first clinically reported case of cat scratch disease (csd) presenting as a focal neurologic deficit in an immunocompetent adult. | 2010 | 20589186 |
| molecular typing of bartonella henselae dna extracted from human clinical specimens and cat isolates in japan. | bartonella henselae is the causative agent of cat scratch disease (csd). to clarify the population structure and relationship between human and cat strains of b. henselae, 55 specimens isolated in japan, including 24 b. henselae dna-positive clinical samples from csd patients and 31 b. henselae isolates from domestic cats, were characterized by multilocus sequence typing (mlst) and the 16s-23s trna-ala/trna-ile intergenic spacer (s1) sequence, which were used previously for strain typing of b. h ... | 2010 | 20602637 |
| does a feline leukemia virus infection pave the way for bartonella henselae infection in cats? | domestic cats serve as the reservoir hosts of bartonella henselae and may develop mild clinical symptoms or none after experimental infection. in humans, b. henselae infection can result in self-limiting cat scratch disease. however, immunocompromised patients may suffer from more-severe courses of infection or may even develop the potentially lethal disease bacillary angiomatosis. it was reasoned that cats with immunocompromising viral infections may react similarly to b. henselae infection. th ... | 2010 | 20610682 |
| identification of the feline humoral immune response to bartonella henselae infection by protein microarray. | bartonella henselae is the zoonotic agent of cat scratch disease and causes potentially fatal infections in immunocompromised patients. understanding the complex interactions between the host's immune system and bacterial pathogens is central to the field of infectious diseases and to the development of effective diagnostics and vaccines. | 2010 | 20625509 |
| neuroretinitis caused by bartonella henselae (cat-scratch disease) in a 13-year-old girl. | cat-scratch disease-related neuroretinitis is a relatively unusual pathology, with suspicious clinical epidemiological and serological diagnosis. we present a case of an adolescent suffering from unilateral neuroretinitis associated with bartonella henselae infection characterized by abrupt loss of vision, optic disc swelling, and macular star exudates with optimal response to antibiotic treatment. | 2010 | 20628521 |
| what's eating you? cat flea (ctenocephalides felis), part 1: clinical features and role as a disease vector. | 2010 | 20540412 | |
| the trw type iv secretion system of bartonella mediates host-specific adhesion to erythrocytes. | bacterial pathogens typically infect only a limited range of hosts; however, the genetic mechanisms governing host-specificity are poorly understood. the alpha-proteobacterial genus bartonella comprises 21 species that cause host-specific intraerythrocytic bacteremia as hallmark of infection in their respective mammalian reservoirs, including the human-specific pathogens bartonella quintana and bartonella bacilliformis that cause trench fever and oroya fever, respectively. here, we have identifi ... | 2010 | 20548954 |
| antimicrobial susceptibility by etest of bartonella henselae isolated from cats and human in japan. | bartonella henselae, a small fastidious gram-negative bacillus, is the causative agent of cat-scratch disease (csd). because of difficulty in isolating the organism, there has been no report on its antibiotic susceptibility in japan. we determined the minimal inhibitory concentrations (mics) of eight antimicrobial agents against 32 isolates of b. henselae (31 from cats and one from a human in japan) by the etest method. mics of all 32 isolates were <0.016 μg/ml for minocycline and ranged from ≤0 ... | 2010 | 20567991 |
| evaluation of topical application of 10% imidacloprid-1% moxidectin to prevent bartonella henselae transmission from cat fleas. | to determine whether monthly topical administration of a combination of 10% imidacloprid and 1% moxidectin would lessen flea (ctenocephalides felis) transmission of bartonella henselae among cats. | 2010 | 20392182 |
| molecular evidence of perinatal transmission of bartonella vinsonii subsp. berkhoffii and bartonella henselae to a child. | bartonella vinsonii subsp. berkhoffii, bartonella henselae, or dna of both organisms was amplified and sequenced from blood, enrichment blood cultures, or autopsy tissues from four family members. historical and microbiological results support perinatal transmission of bartonella species in this family. it is of clinical relevance that bartonella spp. may adversely influence human reproductive performance. | 2010 | 20392912 |
| the batr/bats two-component regulatory system controls the adaptive response of bartonella henselae during human endothelial cell infection. | here, we report the first comprehensive study of bartonella henselae gene expression during infection of human endothelial cells. expression of the main cluster of upregulated genes, comprising the virb type iv secretion system and its secreted protein substrates, is shown to be under the positive control of the transcriptional regulator batr. we demonstrate binding of batr to the promoters of the virb operon and a substrate-encoding gene and provide biochemical evidence that batr and bats const ... | 2010 | 20418395 |
| rare infections mimicking ms. | the diagnosis of multiple sclerosis (ms), despite well defined clinical criteria is not always simple. on many occasions it is difficult to differentiate ms from various non-ms idiopathic demyelinating disorders, specific and infectious inflammatory diseases or non-inflammatory demyelinating diseases. clinicians should be aware of various clinical and mri "red flags" that may point to the other diagnosis and demand further diagnostic evaluation. it is generally accepted that atypical clinical sy ... | 2010 | 20439131 |
| molecular mechanisms of bartonella henselae resistance to azithromycin, pradofloxacin and enrofloxacin. | 2010 | 20022937 | |
| [bartonella henselae, an ubiquitous agent of proteiform zoonotic disease]. | bartonella henselae is the causative agent of cat scratch disease, a human infection usually characterized by persistent regional lymphadenopathy. it is transmitted to humans by cat scratches or bites. cats are the major reservoir for this bacterium thus b. henselae has a worldwide distribution. the bacterial pathogenicity may bay emphasized by the immune status of the infected host. angiomatosis or hepatic peliosis are the most frequent clinical manifestations in immunocompromised patients. b. ... | 2010 | 20042306 |
| high prevalence of antibodies against bartonella henselae with cervical lymphadenopathy in children. | cat-scratch disease is the most common form of bartonella henselae infection. although reports have shown that csd is relatively common, they have not shown the prevalence of seropositivity for bartonella henselae in cases of cervical lymphadenitis and kawasaki disease, which are relatively common diseases in children. | 2010 | 20059723 |
| prevalence of bartonella henselae and borrelia burgdorferi sensu lato dna in ixodes ricinus ticks in europe. | bartonella spp. can cause persistent bloodstream infections in humans and animals. to determine whether bartonella henselae is present in questing ixodes ricinus ticks, we analyzed the prevalence of b. henselae dna among tick stages compared to the prevalence of dna from borrelia burgdorferi sensu lato, the pathogen most frequently transmitted by ticks. b. henselae dna was present with a prevalence of up to approximately 40% in tick populations sampled in four european sites (eberdingen, germany ... | 2010 | 20061459 |
| blood cell findings resembling bartonella spp. | some bartonella species are able to invade red blood cells (rbc) and may cause persistent infection in the susceptible host. use of transmission electron microscopy (tem) demonstrates, inside erythrocytes, the typical triple-walled agents. however, when examining ultrathin sections of blood cells, the authors have, on several occasions, detected intraerythrocytic abnormalities that mimic but are not typical of bartonella spp. small endovesicles, pseudoinclusions, cavities, and irregular hemoglob ... | 2010 | 20070147 |
| scalp eschar and neck lymphadenopathy caused by bartonella henselae after tick bite. | rickettsia slovaca and rickettsia raoultii have been associated with a syndrome characterized by scalp eschar and neck lymphadenopathy following tick bites. however, in many cases, the causative agent remains undetermined. we report 3 cases of this syndrome caused by bartonella henselae, and we propose the term "senlat" to collectively describe this clinical entity. | 2010 | 20070235 |
| renal microabscesses due to bartonella infection. | we report a case of cat scratch disease with bilateral renal microabscesses. this case is unique in that there were no other abscesses found intrabdominally. a previously healthy child was admitted with a 12-day history of fever and headaches. bartonella henselae titers were initially igg 1:640 and igm 1:100, and later igg >1:2560 and igm >1:800. an abdominal ultrasound examination was normal but ct scan revealed microabscesses in both kidneys. | 2010 | 20072078 |
| peliosis hepatis in cats is not associated with bartonella henselae infections. | peliosis hepatis is a vasculoproliferative disorder of the liver with infectious and noninfectious causes. in humans and dogs, bartonella henselae has been linked to peliosis hepatis. although domestic cats are the natural reservoir of b. henselae and although peliosis hepatis is common in this species, an association between this condition and infection with b. henselae has never been investigated in cats. in this study, 26 cases of peliosis hepatis in cats were tested for b. henselae infection ... | 2010 | 20080497 |
| a toddler with facial nodules: a case of idiopathic facial aseptic granuloma. | we describe the case of a 3-year-old boy who presented with several asymptomatic facial nodules present for six months. a skin biopsy obtained from the nodules showed a moderately well-defined granuloma in the superficial and deep dermis. a squamous epithelial lined cyst, extravasated keratin, or shadow cells were not identified. bartonella henselae titers and the coccidioidomycosis immitis immunodiffusion test were negative; a tuberculin skin test was non-reactive. fite, periodic acid-schiff (p ... | 2010 | 20137751 |
| feline immunodeficiency virus, feline leukemia virus and bartonella species in stray cats on st kitts, west indies. | stray cats trapped in various areas of basseterre, the capital of st kitts in the west indies, were tested for infection with feline immunodeficiency virus (fiv) and feline leukemia virus (felv) using commercial kits. of 99 (51 male and 48 female) cats trapped in 2006/7, 15% (12 males and three females) were positive for fiv while none were positive for felv. of 72 (41 males and 31 females) cats trapped in 2009, 14% (nine males and one female) were positive for fiv while none were positive for f ... | 2010 | 20138558 |
| successful treatment of bartonella henselae endocarditis in a cat. | this report describes the clinical presentation, diagnosis and treatment of a cat with vegetative valvular endocarditis temporally associated with natural infection with bartonella henselae. lethargy, abnormal gait and weakness were the main clinical signs that resulted in referral for diagnostic evaluation. using a novel and sensitive culture approach, b henselae was isolated from the blood. following antibiotic therapy there was total resolution of clinical signs, the heart murmur, the valvula ... | 2010 | 20138559 |
| bartonellosis, an increasingly recognized zoonosis. | cat scratch disease is the most common zoonotic infection caused by bartonella bacteria. among the many mammals infected with bartonella spp., cats represent a large reservoir for human infection, as they are the main reservoir for bartonella henselae, bartonella clarridgeiae and bartonella koehlerae. bartonella spp. are vector-borne bacteria, and transmission of b. henselae by cat fleas occurs mainly through infected flea faeces, although new potential vectors (ticks and biting flies) have been ... | 2010 | 20148999 |
| a report of cat scratch disease in korea confirmed by pcr amplification of the 16s-23s rrna intergenic region of bartonella henselae. | we report a case of cat scratch disease in an 8-yr-old girl who presented with fever and enlargement of both axillary lymph nodes. both aerobic and anaerobic cultures of the lymph node aspirate were negative for microbial growth. gram staining and warthin-starry silver staining did not reveal any organism. purified dna from the pcr-amplicon of the 16s-23s rrna intergenic region was sequenced and showed 99.7% identity with the corresponding sequence of bartonella henselae strain houston-1. our fi ... | 2010 | 20197720 |
| [neuroretinitis in cat-scratch disease]. | 2010 | 20199895 | |
| bartonella spp. transmission by ticks not established. | bartonella spp. infect humans and many animal species. mainly because pcr studies have demonstrated bartonella dna in ticks, some healthcare providers believe that these microorganisms are transmitted by ticks. b. henselae, in particular, is regarded as being present in and transmissible by the ixodes scapularis tick. the presence of a microbial agent within a tick, however, does not imply that the tick might transmit it during the course of blood feeding and does not confer epidemiologic import ... | 2010 | 20202410 |
| evaluation of sensitivity, specificity and cross-reactivity in bartonella henselae serology. | 2010 | 20223899 | |
| prevalence and seasonality of tick-borne pathogens in questing ixodes ricinus ticks from luxembourg. | in europe, ixodid ticks are important arthropod vectors of human and animal pathogens, but comprehensive studies of the prevalence of all relevant pathogens in central europe are scarce. as a result of ecological changes, the incidences of tick-borne infections are expected to increase. in this study, 1,394 nymphal and adult ixodes ricinus ticks sampled monthly during the active season from 33 ecologically distinct collection sites throughout luxembourg were screened for all human tick-borne pat ... | 2010 | 20228110 |
| effects of prolonged formalin fixation on the immunohistochemical detection of infectious agents in formalin-fixed, paraffin-embedded tissues. | immunohistochemistry is commonly used to detect and characterize infectious agents in diagnostic pathology. the principal advantage of immunohistochemistry over other antigen detection techniques is the ability to identify antigen within the context of histologic lesions. although epitope masking attributed to formalin fixation, especially prolonged fixation, has been considered a limiting factor in diagnostic immunohistochemistry, only a few studies have evaluated the immunohistochemical detect ... | 2010 | 20332424 |
| [a clinical case of spontaneous involution of systemic cat scratch disease]. | typical cat-scratch disease (csd) manifests as regional lymphadenopathy following cat scratch and sometimes associated with mild fever. there is a lot of atypical manifestations and some of those have systemic involvement. hepatosplenic csd is a systemic presentation associating fever of unknown origin with nodules in the liver and/or the spleen. ultrasound abdominal examination shows nodules (3-30 mm) in the spleen and/or in the liver. diagnostic is based on serology for b henselae (always igg ... | 2010 | 20344917 |
| blood donor infected with bartonella henselae. | 2010 | 20345384 | |
| isolation and characterization of bartonella strains in cats in italy. | bartonella henselae and bartonella clarridgeiae were isolated in two cats in sardinia, italy. infection by b. clarridgeiae was characterized by fever and submandibular lymph nodes enlargement while b. henselae infection was asymptomatic. this is the first report of b. clarridgeiae in a cat in italy and the first isolation of b. henselae and b. clarridgeiae in sardinia. | 2010 | 20345572 |
| bacillary angiomatosis in an immunosuppressed dog. | abstract a dog being treated with immunosuppressive doses of prednisone and azathioprine for pancytopenia of unknown origin, developed, over a 2-week period, multiple erythematous nodular lesions in the skin including footpads. skin samples revealed lesions identical to those of human bacillary angiomatosis (ba). the nodules were composed of multifocal proliferations of capillaries, each lined by protuberant endothelial cells. the capillary clusters were separated by an oedematous connective tis ... | 2010 | 20374571 |
| bartonella vinsonii subsp. berkhoffii and bartonella henselae bacteremia in a father and daughter with neurological disease. | abstract: | 2010 | 20377863 |
| skin diseases associated with bartonella infection: facts and controversies. | the genus bartonella is composed of a series of species and subspecies. ten of them are responsible for human infections. the best-identified diseases are cat scratch disease (b henselae and possibly b clarridgeiae), trench fever (b quintana), bacillary angiomatosis (b quintana and b henselae), and the spectrum of verruga peruana, carrion disease, and oroya fever (b bacilliformis). controversies exist about the implication of a few other microorganisms being involved in these diseases. several o ... | 2010 | 20797506 |
| bartonella genotypes in fleas (insecta: siphonaptera) collected from rodents in the negev desert, israel. | fleas collected from rodents in the negev desert in southern israel were molecularly screened for bartonella species. a total of 1,148 fleas, collected from 122 rodents belonging to six species, were pooled in 245 pools based on flea species, sex, and rodent host species. two bartonella gene fragments, corresponding to rna polymerase b (rpob) and citrate synthase (glta), were targeted, and 94 and 74 flea pools were found positive by pcr, respectively. the bartonella 16s-23s internal transcribed ... | 2010 | 20802081 |
| bartonella species, feline herpesvirus-1, and toxoplasma gondii pcr assay results from blood and aqueous humor samples from 104 cats with naturally occurring endogenous uveitis. | toxoplasma gondii, bartonella henselae and feline herpesvirus-1 (fhv-1) have been implicated as causative agents in feline uveitis. the usefulness of serum and aqueous humor (ah) antibody testing for these agents is limited as antibodies can be detected in both healthy cats and cats with uveitis. very few studies using polymerase chain reaction (pcr) assays to amplify organism dna from samples from cats with uveitis have been performed. in this study, assays to detect t gondii antibodies, feline ... | 2010 | 20817587 |
| cat scratch disease and arthropod vectors: more to it than a scratch? | cat scratch disease is a common infection, particularly in children, and clinicians need to be aware of its potential transmission to humans by arthropod vectors such as fleas and ticks in addition to animal bites and scratches. the absence of a vertebrate bite or scratch does not preclude infection with bartonella henselae. | 2010 | 20823366 |
| [neuroretinitis in cat scratch disease]. | purpose: to present two cases of neuroretinitis in cat scratch disease we present two girls treated in department of ophthalmology of poznai university of medical sciences because of unilateral, painless decrease of vision. both patients presented following cat exposure fever and lymph nodes swelling. ophthalmoscopic findings was neuroretinitis (optic disc edema with the macular star). bartonella henselae antibody titers (igg) were elevated. csd is usually self-limited infection in immunocompete ... | 2010 | 20825068 |
| impairment of circulating endothelial progenitors in down syndrome. | pathological angiogenesis represents a critical issue in the progression of many diseases. down syndrome is postulated to be a systemic anti-angiogenesis disease model, possibly due to increased expression of anti-angiogenic regulators on chromosome 21. the aim of our study was to elucidate some features of circulating endothelial progenitor cells in the context of this syndrome. | 2010 | 20836844 |
| a first japanese case of bartonella henselae-induced endocarditis diagnosed by prolonged culture of a specimen from the excised valve. | bartonella henselae, the causative agent of cat scratch disease, is increasingly recognized as a cause of culture-negative endocarditis. this report describes the first japanese case, which was diagnosed after a prolonged culture of the excised aortic valve. high igg and igm titers to b. henselae pointed to a subacute course of the disease. | 2010 | 20846591 |