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chloroquine-resistant falciparum malaria in east kalimantan, indonesia.following the discovery of four imported chloroquine-resistant p. falciparum infections in the province of yogyakarta (island of java) sensitivity tests were carried out in the province of east kalimantan island of borneo). twenty subjects were given 25 mg. of chloroquine base per kilogram of body weight over three days. two infections were found resistant at the rii level and a third at the ri level with early recrudescence on day 7. in the other 17 cases followed up to day 21, six were found a ...1976772235
[letter: a recent case of human babesiasis]. 1976772600
histamine changes in plasmodium falciparum malaria.histamine, serum complement factor 3 (c'3) and platelets were studied in 33 plasmodium falciparum patients. elevation of histamine level in the blood was found during acute infection but was more marked in the group of patients with systemic complications. a correlation between histamine changes, clinical complications, reduction of c'3 and degree of thrombocytopenia was observed. the possible role of histamine in the development of complications in p. falciparum infection and the possible relea ...1976772896
a new look at the protection of hemoglobin as and ac genotypes against plasmodium falciparum infection: a census tract approach.a total of 4,097 randomly selected children under 5 years in accra, ghana were investigated for hb type, malarial parasite species, and parasite density. even though malarial infection rates in this metropolitan population were lower as compared to holoendemic areas, the differential survival of hb s carriers was confirmed. in addition, similar but less pronounced survival effects were seen in hb c heterozygotes. hb s carriers had the highest infection rates. more females than males were infecte ...1976773175
glucose-6-phosphate and 6-phosphogluconate dehydrogenase activities human erythrocytes infected with plasmodium falciparum. 1976773316
editorial: new look at malaria. 1976773496
quinine disposition during malaria and during induced fever.quinine disposition was studied in 5 subjects before and during an experimentally induced infection with a chloroquine-resistant strain of plasmodium falciparum and in 2 individuals before and during artificially induced fever. plasma quinine levels were determined by both a benzene extraction method (qb), which measures principally unmetabolized quinine, and a metaphosphoric acid precipitation method (qmpa), which measures quinine and quinine metabolites. the ratio qb/qmpa in plasma was used to ...1976773582
chloroquine-resistant falciparum malaria from irian jaya (indonesian new guinea).a strain of plasmodium falciparum, transmitted in irian jaya (indonesian new guinea) was isolated in 1974 and sent to the university of maryland for characterization in nonimmune volunteers. at maryland the indonesia (whit.) strain, as it has been designated, was transmitted to colonized anopheles stephensi. prophylactically, it was not suppressed by proguanil hydrochloride 100 mg. daily. curatively, parasitaemia was not cleared by treatment with 1-5 g. (base) in three days of chloroquine or amo ...1976775119
[malaria prophylaxis]. 1976775347
parasitic infections in humans in west kalimantan (borneo), indonesia.a survey was carried out among inhabitants of eight villages in west kalimantan province (borneo), whereby blood smears were examined for malaria, stools examined for intestinal parasites and sera tested by the indirect hemagglutination test for antibodies to entamoeba histolytica and toxoplasma gondii. the prevalence of malaria among 3017 people examined was 5.6% (plasmodium vivax 2.8%, plasmodium falciparum 2.8%). brugia malayi microfilariae were found in 3.6% and wuchereria bancrofti in 0.3%. ...1976788263
malaria threat to the seychelles. 1976788847
[a surprising cause of error in platelet counting: intra-erythrocyte trophozoites]. 1976790317
[comparative evaluation of three antigens for the serodiagnosis of malaria (author's transl)]. 1976790380
vaccination against plasmodium falciparum: a negative result. 1976790673
the blood groups, serum groups, red-cell isoenzymes and haemoglobins of the sandawe and nyaturu of tanzania.blood specimens from members of the click-speaking sandawe tribe of tanzania and of the adjacent bantu-speaking nyaturu tribe have been tested for antigens of 11 blood group systems, for variants of 3 plasma-protein systems and 9 red-cell-enzyme systems, for haemoglobin variants. the results are tabulated and gene frequencies computed. for most systems, the frequencies in the two tribes are similar to one another and, in so far as data are available, similar to the neighbouring bantu-speaking tr ...1976791061
chemoprophylaxis of malaria. 1976791446
preliminary studies on the response of plasmodium falciparum to chloroquine in the philippines, with the in vitro technique.previous investigations had shown that resistance to standard regimens of chloroquine occurred in some cases of falciparum infection in the philippines. more extensive investigations into this phenomenon were planned by the malaria eradication service, by means of the in vitro technique developed by rieckmann, in order to determine both the distribution of resistant strains throughout the country and their local incidence. before these studies were undertaken, a series of observations were made ...1976791531
chloroquine-resistant falciparum malaria in papua new guinea. 1976792661
nursing care study: malaria. 1976792822
a marked reduction in the incidence of cold haemagglutinin in plasmodium falciparum malaria.a survey of cold haemagglutinin using the normal and tyrpsinized group o red blood cells was performed in 101 normal individuals, 139 individuals with plasmodium falciparum malaria, 115 individuals with various infections other than malaria and 46 cases of auto-immune haemolytic anaemia. a marked reduction in the incidence of cold haemagglutinin reacting with the normal group o red blood cell was observed in cases of p. falciparum with parasitaemia higher than 100 000/mm3. although this was also ...1976793545
clinical and laboratory presentation of malaria: an analysis of one thousand subjects with malaria parasitaemia.in the context of this study the ethnic origin of the patients revealed no noteworthy difference in the clinical reaction to the parasite; neither did age or sex of the patients. any minor differences whcih appeared in length of history before seeking treatment and frequency of repeat attacks were more a reflection of the cultural pattern of response to illness (i.e. resort to traditional medicines) and the distance between the patient's home and the doctor rather than any altered response on th ...1976794512
jaundice and hepatomegaly in primary malaria.the hepatic manifestations were studied in 65 patients having uncomplicated primary attacks of vivax and falciparum malaria. hepatomegaly due to a "non-specific reactive hepatitis" occurred in 57% of cases. jaundice occurred in 15% of patients and was invariably associated with hepatomegaly. the clinical syndromes of jaundice and hepatomegaly in uncomplicated primary attacks of malaria have to be distinguished from those related to disorders like viral hepatitis, hepatic amoebiasis, typhoid hepa ...1976794514
plasmodium falciparum gametocytogenesis in vitro. 1976794731
aspects of tropical paediatrics.malnutrition interacting with infectious and parasitic diseases are the main causes of the appalling mortality in childhood in the tropics. the most important single safeguard against these in infancy is breast feeding and the trend now evident to abandon this is a disaster which demands urgent attention. reasons for this trend are discussed. efforts to control infectious diseases, other than smallpox, have had little success and the emergence and spread of dengue haemorrhagic fever in s.e. asia ...1976795103
infectivity of falciparum malaria patients for anopheline mosquitoes before and after chloroquine treatment.the infectivity of 25 falciparum malaria patients for anopheles balabacensis and anopheles minimus, before and after chloroquine therapy, was studied in central thailand. the proportion of patients infective for these mosquitoes was not affected by the administration of chloroquine, however, an elevation was observed in the median values for the numbers of oocysts on the guts of the a. balabacensis, but not the a. minimus, fed on infective patients after initiation of treatment.1976795104
precipitating antibody response to malarial s-antigens.the gel diffusion test has been used to detect antibodies to malarial s-antigens. sera were obtained from entire gambian village communities, from young children with acute p. falciparum malaria, from children convalescent from such infections and from immune adults. in community studies, small selections of s-antigens detected antibody frequently in sera from older persons but rarely in sera from young children. larger panels of antigens detected antibodies in sera from half of 50 malarious chi ...1976795105
gametocytes of plasmodium falciparum: phagocytosis by leucocytes in vivo and in vitro.phagocytosis of the extracellular gametocytes of plasmodium falciparum has been demonstrated in vitro, and in vivo in the bloodmeal within the mosquito midgut. up to 84% of the gametocytes were ingested within two hours in vitro, compared to 7% in the same period in the mosquito gut.1976795106
evaluation of two phenanthrenemethanols for antimalarial activity in man: wr 122,455 and wr 171,669.two phenanthrenemethanols, wr 122,455 and wr 171,669, were tested in man for oral tolerance, toxicity, and efficacy against plasmodium falciparum. in healthy subjects, gastrointestinal symptoms limited single-day dosage of wr 122,455 to 800 mg and wr 171,669 to 1,260 mg. no laboratory abnormalities phototoxicity, or gastrointestinal blood loss were noted in the subjects receiving these drugs. in subjects infected with malaria, wr 122,455 cleared parasitemia when given for 1 day in doses from 440 ...1976795309
an evaluation of malaria fluorescent antibody patterns in several remote island populations of the new hebrides, solomons, western carolines, and new guinea.from a representative sampling of several remote populations living on the banks and torres islands (new hebrides), the eastern and southern districts of the solomon islands, the western caroline islands (u.s. pacific trust territory), west new guinea (indonesia), and papua new guinea, 752 sera were examined for fluorescent antibodies to the four species of human malaria, and the results were compared to already published parasite survey data based on blood smears and medical examinations. antib ...1976795310
[splenic infarction in primary plasmodium falciparum infection]. 1976795334
treatment of p. falciparum infection with chloroquine and primaquine in salem and sathyamangalam towns of tamil nadu. 1976795769
a comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in peninsular malaysia. 1976796479
investigation of imported malaria cases in japan in 1972-1974. 1976796480
chloroquine-resistant falciparum malaria acquired in papua new guinea. 1976796648
additional foci of chloroquine-resistant falciparum malaria in east kalimantan and west irian, indonesia. 1976797072
[human and animal parasitic diseases in the new hebrides].new-hebrides condominium, an archipelago in the south pacific, is a country with a special socio-political environment, due to the duality of its french-british regime. this state of affairs is felt in all areas including public health, where we find french, british and condominial personnel. the pathology of parasitic diseases is essentially tropical with a strong predominance of paludism, at times fatal, and intestinal nematodes; however we rarely find amibiasis or human hydatid disease. stron ...1976797480
[chemotherapy of acute malaria attacks in patients returning from tropical and subtropical countries (author's transl)].the number of primary malaria attacks caused by imported infections notified in the federal republic of germany during the period of 1963 through 1975 has increased five fold from 30 to 154 per year. the total number of deaths in the same period was 55. this gave rise to outline again the established methods of chemotherapy and their parasitological basis. the chloroquine resistance of p. falciparum strains is discussed. no causal relationship exists between drug resistance and the fatalities by ...1976797656
study on inhalation therapy by an indigenous compound on p. vivax and p. falciparum infections--a preliminary communication. 1976797658
malaria. 1976799232
[drug resistance in malaria parasites. 1. the nature of resistance, its distribution and epidemiological implications (review of the literature)]. 1976799239
[drug resistance of malaria parasites. 2. clinical aspects, drug treatment and prevention of drug-resistant malaria]. 1976799242
acute cerebellar syndrome in falciparum malaria. 1976799540
[fluorescent antibodies in the cerebrospinal fluid and serum of patients suspected of cerebral malaria caused by plasmodium falciparum].the authors report the results of indirect immunofluorescent technique used for detecting malarial antibodies in the cerebrospinal fluid and serum of 126 african patients suspected of cerebral malaria from infection with plasmodium falciparum. almost all of them were less than 15 years old and were living in urban unstable hypoendemic areas. malarial antibodies, mainly igg, were found in about 25 0/0 of cerebrospinal fluid samples, whether the patients were admitted for malaria or for any other ...1976799542
heparin in the treatment of cerebral malaria (a preliminary report). 1976800248
chloroquine resistance trials in papua new guinea. 1. maprik and popondetta areas.the response of plasmodium falciparum infections to a standard weight related dose of chloroquine using the w.h.o. extended field test was investigated in the maprik and popondetta areas of papus new guinea. fourteen cases of p. falciparum in maprik and 12 cases at popondetta were followed daily for seven days and weekly for a further three weeks after receiving 25 mg/kg of chloroquine over three days. all subjects responded well, the parasitaemias cleared in all cases by the fourth day after in ...1976800313
estimation of incidence and recovery rates of plasmodium falciparum parasitaemia from longitudinal data.a method is described of estimating the malaria incidence rate ĥ and the recovery rate r from longitudinal data. the method is based on the assumption that the phenomenon of patent parasitaemia can be represented by a reversible two-state catalytic model; it is applicable to all problems that can be represented by such a model.the method was applied to data on falciparum malaria from the west african savanna and the findings suggested that immunity increases the rate of recovery from patent para ...1976800968
malarial nehprosis. 1976801295
chloroquine sensitivity of plasmodium falciparum in ethiopia. ii. results of an in vitro test.field trials were performed in two areas of ethiopia with the rieckmann in vitro test for chloroquine sensitivity of plasmodium falciparum. blood cultures from 82 test subjects showed growth of trophozoites to the schizont stage in control vials. growth in test vials occurred in 21 cultures incubated with chloroquine at concentrations of 0.5 nanomoles or more per ml of blood. in vitro results confirm previous results obtained with an in vivo test.1976769570
febrile illnesses resulting in hospital admission: a bacteriological and serological study in jakarta, indonesia.a study of 741 indonesian patients with fever was carried out in order to determine what serious febrile illnesses are prevalent in jakarta. all patients were hospitalized primarily because of fever and were studied by bacteriological and serological methods. bacteremia due to salmonella typhi (150 cases), s. enteritidis (36 cases), or both (2 cases) was common in both children and adults. one s. enteritidis isolate was chloramphenicol resistant. serological evidence of salmonella infection was ...1976769571
single-dose therapy of falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine.patients with naturally acquired chloroquine-resistant falciparum malaria were studied in thailand. the fixed combination of pyrimethamine 75 mg and sulfadoxine 1,500 mg (adult dose) cured 85% of patients with an average pretreatment parasite count of 60,000 per mm(3). the fixed combination of pyrimethamine 50 mg and 800 mg diformyldapsone (dfd) cured 43% of patients with an average pretreatment parasite count of only 17,000 per mm(3). the difference in cure rates was statistically significant ( ...1976769572
the seroepidemiology of malaria in middle america. iii. serologic assessment of localized plasmodium falciparum epidemics.epidemiologic studies were done in two localities, one in panama and one in el salvador, where outbreaks of plasmodium falciparum malaria occurred. the indirect fluorescent antibody (ifa) method was helpful in defining the intensity of the outbreaks, the species of parasite involved, and, through parallel surveys of adjacent localities, the localized character of outbreaks. in escobal, panama 71 (34%) of 211 persons examined were ifa-positive for p. falciparum, although only 1 positive blood fil ...1976769573
chloroquine sensitivity of plasmodium falciparum in ethiopia. i. results of an in vivo test.the in vivo response of plasmodium falciparum to the who single test dose (10 mg/kg body weight) of chloroquine base was examined in ethiopia at four localities where malaria was meso- or hyperendemic. parasitemias cleared by the 3rd day after chloroquine administration in all of the 150 test subjects. no recrudescences were detected during the 6-day or 11-day follow-up periods. the value of the in vivo test was severely limited by the inability to quarantine subjects and follow them for the 28- ...1976769574
malarial antibodies measured by the indirect hemagglutination test in west african children.the indirect hemagglutination test with plasmodium falciparum antigen was used to measure malarial antibodies in filter paper blood specimens from 527 west african children. a slight decline in antibodies was noted in 6- to 8-month-old children wh o had no malaria parasites in their blood smears. children older than 10 months had similar antibody levels regardless of the presence or absence of demonstrated parasites in blood smears.1976769576
suppressive activity of mefloquine in sporozoite-induced human malaria.mefloquine hydrochloride [wr 142,490; alpha-(2-piperidyl)-2,8-bis(trifluoromethyl)-4-quinolinemethanol hydrochloride] was tested for suppressive effect on sporozoite-induced malaria in nonimmune volunteers living in an area where malaria is not naturally transmitted. single doses of 250 mg were given at weekly intervals, 500 mg at intervals of 2 weeks and 1,000 mg at intervals of 4 weeks, to men bitten by 10 to 15 mosquitoes heavily infected with a chloroquine- and pyrimethamine-resistant strain ...1976769678
the kidney in infectious diseases. 1976129758
clinical and experimental investigation of immune complexes in malaria. 1976133011
[renal involvement in malaria (author's transl)].malaria infection leads to renal involvement. reversible proteinuria accompanies many plasmodial infections. chronic malarial nephrotic syndrome is specifically associated with quartan malaria. acute renal failure is restricted to infections with plasmodium falciparum. the pathogenesis of renal involvement during malarial infections includes immunological mechanisms. it is now realized that there exist at least two types of immunological processes: acute transient immune-complex glomerulonephrit ...1976135874
fetal haemoglobin and malaria.the distribution and growth of plasmodium falciparum was compared in red blood-cells containing either adult or fetal haemoglobins. in in-vitro cultures, cord blood-cells were invaded more readily, but there was a paucity of parasites in cells containing haemoglobin f in the blood of infected infants aged 3-6 months. these findings suggest that p. falciparum may preferentially invade young, metabolically active erythrocytes. there was a significant retardation of parasite growth in vitro in cell ...197673695
parasites which migrate to the brain. 197673713
chloroquine resistant plasmodium falciparum in bangladesh. 1976320730
specificity of the circum-sporozoite precipitation antigen(s) of human and simian malarias. 197660482
a review. innate resistance in malaria. 19767463
fetal haemoglobin and malaria. 197674487
the treatment of malaria.at least four doses of quinine followed by a single dose of mefloquine or by a single dose of sulfadoxine-pyrimethamine are two highly effective regimens for chloroquine-resistant falciparum malaria. mefloquine alone is valuable in ambulant patients. chloroquine-sensitive falciparum malaria can be treated with a course of chloroquine. vivax and all other types of malaria should be treated with sequential chloroquine and primaquine. quinine, by intravenous infusion, is the most effective drug for ...1976764937
malaria in the republic of the philippines. a review.malaria in the republic of the philippines is caused principally by p. falciparum and p. vivax, with the former as predominant species. p. malariae is occasionally reported, while p. ovale is very rare and has been reported only in the island of palawan. malaria is widespread in distribution with prevalence varying from one area to the other. in 1970, the malaria morbidity rate was reported to be 77.6 per 100,000 while the mortality rate was 1.8 per 100,000. case detection activities revealed th ...197721558
in vitro cultivation of the sporogonic stages of plasmodium: a review.complete and continuous in vitro development of the sporogonic stages of the malarial parasite has not yet been accomplished, although success with erythrocytic stages (falciparum malaria) and exoerythrocytic stages (avian malaria) has been achieved. this lag in progress appears to be due to several inherent differences between sporogony and these other sequences of development. the trager-jensen system for in vitro development of erythrocytic stages of plasmodium falciparum results in the forma ...197722406
culture of malaria parasites.a human malaria vaccine that will protect against the blood stages of plasmodium falciparum is dependent upon the continuous cultre of the parasite. scientists have demonstrated that it is now possible to achieve this on a small scale. present expertise needs to be expanded to produce larger quantities of material for antigenic studies and potential vaccine production.197722942
continuous culture of human-malaria parasites. 197764661
[strain related differences in the immunodiagnosis of malaria (author's transl)].in infections with p. falciparum and p. vivax antibody titers were found to differ in relation to strains. various strains of both plasmodium species used as antigens showed differences in their sensitivity in reactions with one patient serum. in p. vivax infections it is supposed that some antibody titer differences are caused by antigen variations.197767686
merozoite vaccination of douroucouli monkeys against falciparum malaria.erythrocytic merozoites of plasmodium falciparum (gambia) were isolated from cultures of schizont-infected human red cells on cf 11 cellulose columns. douroucouli monkeys vaccinated with such preparations stored in liquid nitrogen and then emulsified in freund's complete adjuvant (f.c.a.), were resistant to successive challenges with west african (lagos) and east african (uganda palto-alto) strains of p. falciparum. the induced immunity is specific since vaccination with p. knowlesi merozoites i ...197769057
open heart surgery complicated by postoperative malaria. 197770631
malaria antigen-specific t-cell responsiveness during infection with plasmodium falciparum.protective immunity against plasmodium falciparum develops only after several years of repeated exposure to the malarial parasite. we therefore investigated the possibility that acute malaria was associated with malarial antigen-specific immunosuppression. peripheral lymphocytes of west africans with and without p. falciparum infections were tested for their in vitro proliferative responses to a preparation of p. falciparum antigen. there was no significant difference between the magnitude of th ...197773436
prevention and treatment of malaria. 1977320732
malarial lung: report of a case from africa successfully treated with intermittent positive pressure ventilation.we describe the first recorded case from africa of malarial lung, acute pulmonary insufficiency in plasmodium falciparum malaria. the patient was successfully treated with intermittent positive pressure ventilation (ippv). there was heavy parasitemia, preceding cerebral complications and rapid onset of pulmonary edema in the absence of fluid overload or cardiac failure. a further complication of polyuria from tubular dysfunction developed whilst the patient was being ventilated. ippv may have an ...1977320893
chloroquine-resistant plasmodium falciparum and malaria in africa. 1977324040
cultivation of plasmodium falciparum. 1977324435
fatty acid-free bovine albumin as plasma replacement for in vitro cultivation of plasmodium falciparum. 1977325190
[malaria infection in patients with sickle cell anemia]. 1977325541
pancreatitis complicating falciparum malaria. 1977325545
[clinical aspects of malaria]. 1977325645
chemoprophylaxis of malaria. 1977326335
sequential treatment with quinine and mefloquine or quinine and pyrimethamine-sulfadoxine for falciparum malaria.patients with falciparum malaria were studied in thailand, an area of known chloroquine resistance. the patients were unselected and some had severe malaria, and they were randomly assigned to one of two sequential regimes. a short course of quinine (average 4 doses, equivalent to 2 g base) followed by a single dose of pyrimethamine-sulfadoxine (fansidar) cured 92% of patients (36 out of 39), while a short course of quinine followed by a single 1-5-dose of mefloquine cured all of the 35 patients ...1977326337
evidence for differences in erythrocyte surface receptors for the malarial parasites, plasmodium falciparum and plasmodium knowlesi.human erythrocytes lacking various blood group determinants were susceptible to invasion by plasmodium falciparum including duffy-negative erythrocytes that are refractory to invasion by plasmodium knowlesi. erythrocytes treated with trypsin or neuraminidase had reduced susceptibility of p. falciparum and normal susceptibility to p. knowlesi. chymotrypsin treatment (0.1 mg/ml) blocked invasion only by p. knowlesi. the differential effect of enzymatic cleavage of determinats from the erythrocyte ...1977327014
[a patient with high fever]. 1977327338
[chloroquine resistant tropical malaria imported from surinam]. 1977327340
malaria field studies in a high-incidence coastal area of el salvador, c.a.a three-year investigation was made of the incidence patterns and characteristics of malaria in a small high-incidence coastal area of el salvador with a resident population of about 6,000 persons and a migrant population of 3,000 to 4,000 others. it found a significant increase in the incidence of plasmodium falciparum cases during the three-year period, combined with relative stability in the annual number of plasmodium vivax cases. a close correlation was observed between the seasonal occuren ...1977328096
malaria and hereditary ovalocytosis.hereditary ovalocytosis in papua new guinea is restricted to areas of endemic malaria and may confer increased resistance to the disease. the incidence of malaria was investigated in 1616 melanesiams of known red cell morphology and severity of infection determined in a smaller subsample. ovalocytics tended to be more resistant to severe malarial infections than normocytics. the ratio of parasitaemia in 112 ovalocytics compared with 741 normocytic children was 1.05 for p. falciparum; 0.90 for p. ...1977328370
cerebral malaria.cerebral malaria is an unusual and treatable cause of stupor and coma, and it can present suddenly in a healthy person. it is diagnosed by finding parasites on a blood smear and is treated either with chloroquine or with quinine, pyrimethamine, and sulfadiazine.1977328970
imported malaria in europe. 1977329079
the prevention and treatment of malaria. 1977329080
malaria endemicity among orang asli (malaysian aborigines) as determined by indirect fluorescent antibody tests.fluorescent antibodies were detected in 89% of 288 orang asli (malaysian aborigines) with plasmodium falciparum antigen and in 62% with p. brasilianum (for p. malariae) antigen. blood films from 18 donors were positive for p. falciparum; 2 of them had mixed infection with p. vivax. seven of the p. falciparum-positive blood films were from children in the 2- to 9-year age group. of 17 sera from cord blood, 16 had significant levels of p. falciparum antibody and 14 of p. malariae antibody, the lev ...1977329695
morphologic variants of anopheles albimanus and susceptibility to plasmodium vivax and p. falciparum.three morphologically different, true-breeding phenotypes have been isolated from a strain of anopheles albimanus from lake apastepeque, el salvador. studies with coindigenous strains of plasmodium vivax and p. falciparum show that these phenotypes differ significantly in their susceptibility to malaria parasites. this difference is apparent both in the number of mosquitoes that become infected and the level of infection obtained. variations in malaria susceptibility are markedly greater with p. ...1977329696
malaria along the southernmost fringe of its distribution in africa: epidemiology and control.after more than thirty years of malaria control in northern transvaal with residual insecticides, malaria prevalence has been reduced to a low level. however, low-grade transmission of plasmodium falciparum continues, with periodic focal outbreaks after abnormally high rainfall. from october 1973 to september 1976, the operational and epidemiological factors involved in this residual transmission were studied in over 17 000 people of an area of northern transvaal. incidence surveys based on the ...1977330017
[an entomologic method for the evaluation of the preventive measures used in the campaigns of malaria control]. 1977330300
indirect flourescent antibody tests for plasmodium falciparum infections. 1977333246
the prevention and treatment of malaria. 1977333247
malaria control in the labour forces of the tan-zam railway. 1977333667
alterations of human serum proteins and other biochemical parameters after five to ten days of untreated acute falciparum malaria.untreated malaria for more than 4 days in eleven patients decreased significantly prealbumin, transferrin levels and increased sgot activity when compared with a control group and a group of 10 malaria patients who were admitted to the hospital at an earlier stage of the infection. total protein was significantly lower in the group of patients admitted after five to ten days to hospital compared with the control group. in all malaria patients independent of the duration of the acute infection th ...1977333673
plasmodium falciparum in culture: use of outdated erthrocytes and description of the candle jar method. 1977335035
[present-day problems of malaria. recent acquisitions in immunology]. 1977335485
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