Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| preliminary studies on the response of plasmodium falciparum to chloroquine in the philippines, with the in vitro technique. | previous investigations had shown that resistance to standard regimens of chloroquine occurred in some cases of falciparum infection in the philippines. more extensive investigations into this phenomenon were planned by the malaria eradication service, by means of the in vitro technique developed by rieckmann, in order to determine both the distribution of resistant strains throughout the country and their local incidence. before these studies were undertaken, a series of observations were made ... | 1976 | 791531 |
| nursing care study: malaria. | 1976 | 792822 | |
| [letter: transplacental passage of soluble plasmodial antigens. induction of a specific immune tolerance?]. | 1976 | 778794 | |
| treatment of p. falciparum infection with chloroquine and primaquine in salem and sathyamangalam towns of tamil nadu. | 1976 | 795769 | |
| a comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in peninsular malaysia. | 1976 | 796479 | |
| investigation of imported malaria cases in japan in 1972-1974. | 1976 | 796480 | |
| jaundice and hepatomegaly in primary malaria. | the hepatic manifestations were studied in 65 patients having uncomplicated primary attacks of vivax and falciparum malaria. hepatomegaly due to a "non-specific reactive hepatitis" occurred in 57% of cases. jaundice occurred in 15% of patients and was invariably associated with hepatomegaly. the clinical syndromes of jaundice and hepatomegaly in uncomplicated primary attacks of malaria have to be distinguished from those related to disorders like viral hepatitis, hepatic amoebiasis, typhoid hepa ... | 1976 | 794514 |
| plasmodium falciparum gametocytogenesis in vitro. | 1976 | 794731 | |
| aspects of tropical paediatrics. | malnutrition interacting with infectious and parasitic diseases are the main causes of the appalling mortality in childhood in the tropics. the most important single safeguard against these in infancy is breast feeding and the trend now evident to abandon this is a disaster which demands urgent attention. reasons for this trend are discussed. efforts to control infectious diseases, other than smallpox, have had little success and the emergence and spread of dengue haemorrhagic fever in s.e. asia ... | 1976 | 795103 |
| infectivity of falciparum malaria patients for anopheline mosquitoes before and after chloroquine treatment. | the infectivity of 25 falciparum malaria patients for anopheles balabacensis and anopheles minimus, before and after chloroquine therapy, was studied in central thailand. the proportion of patients infective for these mosquitoes was not affected by the administration of chloroquine, however, an elevation was observed in the median values for the numbers of oocysts on the guts of the a. balabacensis, but not the a. minimus, fed on infective patients after initiation of treatment. | 1976 | 795104 |
| chloroquine-resistant falciparum malaria acquired in papua new guinea. | 1976 | 796648 | |
| additional foci of chloroquine-resistant falciparum malaria in east kalimantan and west irian, indonesia. | 1976 | 797072 | |
| malaria. | 1976 | 799232 | |
| [drug resistance in malaria parasites. 1. the nature of resistance, its distribution and epidemiological implications (review of the literature)]. | 1976 | 799239 | |
| precipitating antibody response to malarial s-antigens. | the gel diffusion test has been used to detect antibodies to malarial s-antigens. sera were obtained from entire gambian village communities, from young children with acute p. falciparum malaria, from children convalescent from such infections and from immune adults. in community studies, small selections of s-antigens detected antibody frequently in sera from older persons but rarely in sera from young children. larger panels of antigens detected antibodies in sera from half of 50 malarious chi ... | 1976 | 795105 |
| gametocytes of plasmodium falciparum: phagocytosis by leucocytes in vivo and in vitro. | phagocytosis of the extracellular gametocytes of plasmodium falciparum has been demonstrated in vitro, and in vivo in the bloodmeal within the mosquito midgut. up to 84% of the gametocytes were ingested within two hours in vitro, compared to 7% in the same period in the mosquito gut. | 1976 | 795106 |
| [drug resistance of malaria parasites. 2. clinical aspects, drug treatment and prevention of drug-resistant malaria]. | 1976 | 799242 | |
| acute cerebellar syndrome in falciparum malaria. | 1976 | 799540 | |
| [fluorescent antibodies in the cerebrospinal fluid and serum of patients suspected of cerebral malaria caused by plasmodium falciparum]. | the authors report the results of indirect immunofluorescent technique used for detecting malarial antibodies in the cerebrospinal fluid and serum of 126 african patients suspected of cerebral malaria from infection with plasmodium falciparum. almost all of them were less than 15 years old and were living in urban unstable hypoendemic areas. malarial antibodies, mainly igg, were found in about 25 0/0 of cerebrospinal fluid samples, whether the patients were admitted for malaria or for any other ... | 1976 | 799542 |
| evaluation of two phenanthrenemethanols for antimalarial activity in man: wr 122,455 and wr 171,669. | two phenanthrenemethanols, wr 122,455 and wr 171,669, were tested in man for oral tolerance, toxicity, and efficacy against plasmodium falciparum. in healthy subjects, gastrointestinal symptoms limited single-day dosage of wr 122,455 to 800 mg and wr 171,669 to 1,260 mg. no laboratory abnormalities phototoxicity, or gastrointestinal blood loss were noted in the subjects receiving these drugs. in subjects infected with malaria, wr 122,455 cleared parasitemia when given for 1 day in doses from 440 ... | 1976 | 795309 |
| symptoms and signs of malaria. | in addition to asking their patients about recent foreign travel, canadian doctors need to be aware of what features to ask about in considering imported illnesses. of these illnesses, malaria is one of the most common and serious. because of its cerebral renal, pulmonary and intestinal complications, falciparum malaria must be distinguished from non-falciparum forms. anyone with a fever who has arrived recently from an endemic area should be tested for malaria. in addition, headache, malaise, m ... | 1976 | 782678 |
| lung uptake of 99mtc-sulfur colloid in falciparum malaria: case report. | increased lung uptake of 99mtc-sulfur colloid was seen during liver scanning in a patient with falciparum malaria. this finding was due to the enhanced activity of the phagocytic cells of the reticuloendothelial system in the liver, spleen, and lung found in human and experimental malaria. similar findings in other clinical situations and the relevant literature are reviewed. | 1976 | 784917 |
| studies on the resistance of malaria to chloroquine and to a combination of chloroquine and pyrimethamine in peninsular malaysia. | in vivo chloroquine resistance surveys, which allowed for detection of late recrudescing ri resistance, were conducted in three regions of peninsular malaysia, which were previously not recognized as having appreciable drug resistance. among the 485 plasmodium falciparum infections tested resistance rates ranged locally from 20% to 67% in those with parasitaemias over 1,000 per mm3, and 5% to 59% in all parasitaemias. the region found to have the most serious resistance was western pahang. in on ... | 1976 | 785725 |
| [human and animal parasitic diseases in the new hebrides]. | new-hebrides condominium, an archipelago in the south pacific, is a country with a special socio-political environment, due to the duality of its french-british regime. this state of affairs is felt in all areas including public health, where we find french, british and condominial personnel. the pathology of parasitic diseases is essentially tropical with a strong predominance of paludism, at times fatal, and intestinal nematodes; however we rarely find amibiasis or human hydatid disease. stron ... | 1976 | 797480 |
| [chemotherapy of acute malaria attacks in patients returning from tropical and subtropical countries (author's transl)]. | the number of primary malaria attacks caused by imported infections notified in the federal republic of germany during the period of 1963 through 1975 has increased five fold from 30 to 154 per year. the total number of deaths in the same period was 55. this gave rise to outline again the established methods of chemotherapy and their parasitological basis. the chloroquine resistance of p. falciparum strains is discussed. no causal relationship exists between drug resistance and the fatalities by ... | 1976 | 797656 |
| study on inhalation therapy by an indigenous compound on p. vivax and p. falciparum infections--a preliminary communication. | 1976 | 797658 | |
| two cases of malaria presenting with psychiatric symptoms. | mood and behavior disorder may appear either due to primary psychiatric disorder or may signify an underlying, frequently undetected, physical pathology. two instances of malaria falciparum presenting with psychosocial symptomatology are described. | 1976 | 786382 |
| parasitic infections in humans in west kalimantan (borneo), indonesia. | a survey was carried out among inhabitants of eight villages in west kalimantan province (borneo), whereby blood smears were examined for malaria, stools examined for intestinal parasites and sera tested by the indirect hemagglutination test for antibodies to entamoeba histolytica and toxoplasma gondii. the prevalence of malaria among 3017 people examined was 5.6% (plasmodium vivax 2.8%, plasmodium falciparum 2.8%). brugia malayi microfilariae were found in 3.6% and wuchereria bancrofti in 0.3%. ... | 1976 | 788263 |
| malaria threat to the seychelles. | 1976 | 788847 | |
| [a surprising cause of error in platelet counting: intra-erythrocyte trophozoites]. | 1976 | 790317 | |
| vaccination against plasmodium falciparum: a negative result. | 1976 | 790673 | |
| heparin in the treatment of cerebral malaria (a preliminary report). | 1976 | 800248 | |
| chloroquine resistance trials in papua new guinea. 1. maprik and popondetta areas. | the response of plasmodium falciparum infections to a standard weight related dose of chloroquine using the w.h.o. extended field test was investigated in the maprik and popondetta areas of papus new guinea. fourteen cases of p. falciparum in maprik and 12 cases at popondetta were followed daily for seven days and weekly for a further three weeks after receiving 25 mg/kg of chloroquine over three days. all subjects responded well, the parasitaemias cleared in all cases by the fourth day after in ... | 1976 | 800313 |
| the blood groups, serum groups, red-cell isoenzymes and haemoglobins of the sandawe and nyaturu of tanzania. | blood specimens from members of the click-speaking sandawe tribe of tanzania and of the adjacent bantu-speaking nyaturu tribe have been tested for antigens of 11 blood group systems, for variants of 3 plasma-protein systems and 9 red-cell-enzyme systems, for haemoglobin variants. the results are tabulated and gene frequencies computed. for most systems, the frequencies in the two tribes are similar to one another and, in so far as data are available, similar to the neighbouring bantu-speaking tr ... | 1976 | 791061 |
| chloroquine-resistant falciparum malaria in papua new guinea. | 1976 | 792661 | |
| a marked reduction in the incidence of cold haemagglutinin in plasmodium falciparum malaria. | a survey of cold haemagglutinin using the normal and tyrpsinized group o red blood cells was performed in 101 normal individuals, 139 individuals with plasmodium falciparum malaria, 115 individuals with various infections other than malaria and 46 cases of auto-immune haemolytic anaemia. a marked reduction in the incidence of cold haemagglutinin reacting with the normal group o red blood cell was observed in cases of p. falciparum with parasitaemia higher than 100 000/mm3. although this was also ... | 1976 | 793545 |
| the prevalence of babesia antibodies in nigerians. | 1976 | 770357 | |
| peripheral lymphocyte subpopulations in human falciparum malaria. | the concentration of circulating t, b, and 'null' lymphocytes was determined in thirty children and three adults with plasmodium falciparum infections in west africa. during infection, both percentage as well as concentration of t cells were decreased as compared to levels following treatment. the percentage but not concentration of b cells was increased. both percentage and concentration of 'null' cells were increased in malaria. patients with splenomegaly had the most severe alterations in t-c ... | 1976 | 780013 |
| lack of a circadian rhythm in the ability of the gametocytes of plasmodium falciparum to infect anopheles gambiae. | 1976 | 786919 | |
| method to test inhibitory antibodies in human sera to wild populations of plasmodium falciparum. | 1976 | 787801 | |
| a new look at the protection of hemoglobin as and ac genotypes against plasmodium falciparum infection: a census tract approach. | a total of 4,097 randomly selected children under 5 years in accra, ghana were investigated for hb type, malarial parasite species, and parasite density. even though malarial infection rates in this metropolitan population were lower as compared to holoendemic areas, the differential survival of hb s carriers was confirmed. in addition, similar but less pronounced survival effects were seen in hb c heterozygotes. hb s carriers had the highest infection rates. more females than males were infecte ... | 1976 | 773175 |
| the seroepidemiology of malaria in middle america. iii. serologic assessment of localized plasmodium falciparum epidemics. | epidemiologic studies were done in two localities, one in panama and one in el salvador, where outbreaks of plasmodium falciparum malaria occurred. the indirect fluorescent antibody (ifa) method was helpful in defining the intensity of the outbreaks, the species of parasite involved, and, through parallel surveys of adjacent localities, the localized character of outbreaks. in escobal, panama 71 (34%) of 211 persons examined were ifa-positive for p. falciparum, although only 1 positive blood fil ... | 1976 | 769573 |
| chloroquine-resistant falciparum malaria in east kalimantan, indonesia. | following the discovery of four imported chloroquine-resistant p. falciparum infections in the province of yogyakarta (island of java) sensitivity tests were carried out in the province of east kalimantan island of borneo). twenty subjects were given 25 mg. of chloroquine base per kilogram of body weight over three days. two infections were found resistant at the rii level and a third at the ri level with early recrudescence on day 7. in the other 17 cases followed up to day 21, six were found a ... | 1976 | 772235 |
| histamine changes in plasmodium falciparum malaria. | histamine, serum complement factor 3 (c'3) and platelets were studied in 33 plasmodium falciparum patients. elevation of histamine level in the blood was found during acute infection but was more marked in the group of patients with systemic complications. a correlation between histamine changes, clinical complications, reduction of c'3 and degree of thrombocytopenia was observed. the possible role of histamine in the development of complications in p. falciparum infection and the possible relea ... | 1976 | 772896 |
| chloroquine sensitivity of plasmodium falciparum in ethiopia. i. results of an in vivo test. | the in vivo response of plasmodium falciparum to the who single test dose (10 mg/kg body weight) of chloroquine base was examined in ethiopia at four localities where malaria was meso- or hyperendemic. parasitemias cleared by the 3rd day after chloroquine administration in all of the 150 test subjects. no recrudescences were detected during the 6-day or 11-day follow-up periods. the value of the in vivo test was severely limited by the inability to quarantine subjects and follow them for the 28- ... | 1976 | 769574 |
| malarial antibodies measured by the indirect hemagglutination test in west african children. | the indirect hemagglutination test with plasmodium falciparum antigen was used to measure malarial antibodies in filter paper blood specimens from 527 west african children. a slight decline in antibodies was noted in 6- to 8-month-old children wh o had no malaria parasites in their blood smears. children older than 10 months had similar antibody levels regardless of the presence or absence of demonstrated parasites in blood smears. | 1976 | 769576 |
| suppressive activity of mefloquine in sporozoite-induced human malaria. | mefloquine hydrochloride [wr 142,490; alpha-(2-piperidyl)-2,8-bis(trifluoromethyl)-4-quinolinemethanol hydrochloride] was tested for suppressive effect on sporozoite-induced malaria in nonimmune volunteers living in an area where malaria is not naturally transmitted. single doses of 250 mg were given at weekly intervals, 500 mg at intervals of 2 weeks and 1,000 mg at intervals of 4 weeks, to men bitten by 10 to 15 mosquitoes heavily infected with a chloroquine- and pyrimethamine-resistant strain ... | 1976 | 769678 |
| single-dose therapy of falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. | patients with naturally acquired chloroquine-resistant falciparum malaria were studied in thailand. the fixed combination of pyrimethamine 75 mg and sulfadoxine 1,500 mg (adult dose) cured 85% of patients with an average pretreatment parasite count of 60,000 per mm(3). the fixed combination of pyrimethamine 50 mg and 800 mg diformyldapsone (dfd) cured 43% of patients with an average pretreatment parasite count of only 17,000 per mm(3). the difference in cure rates was statistically significant ( ... | 1976 | 769572 |
| complement and malaria. | 1976 | 779685 | |
| febrile illnesses resulting in hospital admission: a bacteriological and serological study in jakarta, indonesia. | a study of 741 indonesian patients with fever was carried out in order to determine what serious febrile illnesses are prevalent in jakarta. all patients were hospitalized primarily because of fever and were studied by bacteriological and serological methods. bacteremia due to salmonella typhi (150 cases), s. enteritidis (36 cases), or both (2 cases) was common in both children and adults. one s. enteritidis isolate was chloramphenicol resistant. serological evidence of salmonella infection was ... | 1976 | 769571 |
| chloroquine sensitivity of plasmodium falciparum in ethiopia. ii. results of an in vitro test. | field trials were performed in two areas of ethiopia with the rieckmann in vitro test for chloroquine sensitivity of plasmodium falciparum. blood cultures from 82 test subjects showed growth of trophozoites to the schizont stage in control vials. growth in test vials occurred in 21 cultures incubated with chloroquine at concentrations of 0.5 nanomoles or more per ml of blood. in vitro results confirm previous results obtained with an in vivo test. | 1976 | 769570 |
| [malaria prophylaxis]. | 1976 | 775347 | |
| the treatment of malaria. | at least four doses of quinine followed by a single dose of mefloquine or by a single dose of sulfadoxine-pyrimethamine are two highly effective regimens for chloroquine-resistant falciparum malaria. mefloquine alone is valuable in ambulant patients. chloroquine-sensitive falciparum malaria can be treated with a course of chloroquine. vivax and all other types of malaria should be treated with sequential chloroquine and primaquine. quinine, by intravenous infusion, is the most effective drug for ... | 1976 | 764937 |
| editorial: new look at malaria. | 1976 | 773496 | |
| [letter: a recent case of human babesiasis]. | 1976 | 772600 | |
| the kidney in infectious diseases. | 1976 | 129758 | |
| [renal involvement in malaria (author's transl)]. | malaria infection leads to renal involvement. reversible proteinuria accompanies many plasmodial infections. chronic malarial nephrotic syndrome is specifically associated with quartan malaria. acute renal failure is restricted to infections with plasmodium falciparum. the pathogenesis of renal involvement during malarial infections includes immunological mechanisms. it is now realized that there exist at least two types of immunological processes: acute transient immune-complex glomerulonephrit ... | 1976 | 135874 |
| chloroquine resistant plasmodium falciparum in bangladesh. | 1976 | 320730 | |
| clinical and experimental investigation of immune complexes in malaria. | 1976 | 133011 | |
| parasites which migrate to the brain. | 1976 | 73713 | |
| fetal haemoglobin and malaria. | the distribution and growth of plasmodium falciparum was compared in red blood-cells containing either adult or fetal haemoglobins. in in-vitro cultures, cord blood-cells were invaded more readily, but there was a paucity of parasites in cells containing haemoglobin f in the blood of infected infants aged 3-6 months. these findings suggest that p. falciparum may preferentially invade young, metabolically active erythrocytes. there was a significant retardation of parasite growth in vitro in cell ... | 1976 | 73695 |
| a review. innate resistance in malaria. | 1976 | 7463 | |
| fetal haemoglobin and malaria. | 1976 | 74487 | |
| specificity of the circum-sporozoite precipitation antigen(s) of human and simian malarias. | 1976 | 60482 | |
| malaria antigen-specific t-cell responsiveness during infection with plasmodium falciparum. | protective immunity against plasmodium falciparum develops only after several years of repeated exposure to the malarial parasite. we therefore investigated the possibility that acute malaria was associated with malarial antigen-specific immunosuppression. peripheral lymphocytes of west africans with and without p. falciparum infections were tested for their in vitro proliferative responses to a preparation of p. falciparum antigen. there was no significant difference between the magnitude of th ... | 1977 | 73436 |
| open heart surgery complicated by postoperative malaria. | 1977 | 70631 | |
| merozoite vaccination of douroucouli monkeys against falciparum malaria. | erythrocytic merozoites of plasmodium falciparum (gambia) were isolated from cultures of schizont-infected human red cells on cf 11 cellulose columns. douroucouli monkeys vaccinated with such preparations stored in liquid nitrogen and then emulsified in freund's complete adjuvant (f.c.a.), were resistant to successive challenges with west african (lagos) and east african (uganda palto-alto) strains of p. falciparum. the induced immunity is specific since vaccination with p. knowlesi merozoites i ... | 1977 | 69057 |
| [strain related differences in the immunodiagnosis of malaria (author's transl)]. | in infections with p. falciparum and p. vivax antibody titers were found to differ in relation to strains. various strains of both plasmodium species used as antigens showed differences in their sensitivity in reactions with one patient serum. in p. vivax infections it is supposed that some antibody titer differences are caused by antigen variations. | 1977 | 67686 |
| culture of malaria parasites. | a human malaria vaccine that will protect against the blood stages of plasmodium falciparum is dependent upon the continuous cultre of the parasite. scientists have demonstrated that it is now possible to achieve this on a small scale. present expertise needs to be expanded to produce larger quantities of material for antigenic studies and potential vaccine production. | 1977 | 22942 |
| in vitro cultivation of the sporogonic stages of plasmodium: a review. | complete and continuous in vitro development of the sporogonic stages of the malarial parasite has not yet been accomplished, although success with erythrocytic stages (falciparum malaria) and exoerythrocytic stages (avian malaria) has been achieved. this lag in progress appears to be due to several inherent differences between sporogony and these other sequences of development. the trager-jensen system for in vitro development of erythrocytic stages of plasmodium falciparum results in the forma ... | 1977 | 22406 |
| malaria in the republic of the philippines. a review. | malaria in the republic of the philippines is caused principally by p. falciparum and p. vivax, with the former as predominant species. p. malariae is occasionally reported, while p. ovale is very rare and has been reported only in the island of palawan. malaria is widespread in distribution with prevalence varying from one area to the other. in 1970, the malaria morbidity rate was reported to be 77.6 per 100,000 while the mortality rate was 1.8 per 100,000. case detection activities revealed th ... | 1977 | 21558 |
| continuous culture of human-malaria parasites. | 1977 | 64661 | |
| looking back for a view of the future: observations on immunity to induced malaria. | 1977 | 74211 | |
| resistance to antimalarials by plasmodium falciparum in burma. | 1977 | 142304 | |
| biomedical survey in irian jaya (west irian), indonesia. | a biomedical survey was conducted in several areas of irian jaya, indonesia in july 1972 in association with an investigation of reports of a cholera outbreak. stool specimens, blood smears and sera were collected and examined for evidence of parasitic as well as other infectious diseases. a total of 114 stools were examined and the most commonly found intestinal parasites were trichuris trichiura (94%), ascaris lumbricoides (74%), hookworm (58%), entamoeba coli (15%), endolimax nana (8%), entam ... | 1977 | 208184 |
| prevention and treatment of malaria. | 1977 | 320732 | |
| malarial lung: report of a case from africa successfully treated with intermittent positive pressure ventilation. | we describe the first recorded case from africa of malarial lung, acute pulmonary insufficiency in plasmodium falciparum malaria. the patient was successfully treated with intermittent positive pressure ventilation (ippv). there was heavy parasitemia, preceding cerebral complications and rapid onset of pulmonary edema in the absence of fluid overload or cardiac failure. a further complication of polyuria from tubular dysfunction developed whilst the patient was being ventilated. ippv may have an ... | 1977 | 320893 |
| chloroquine-resistant plasmodium falciparum and malaria in africa. | 1977 | 324040 | |
| fatty acid-free bovine albumin as plasma replacement for in vitro cultivation of plasmodium falciparum. | 1977 | 325190 | |
| [malaria infection in patients with sickle cell anemia]. | 1977 | 325541 | |
| pancreatitis complicating falciparum malaria. | 1977 | 325545 | |
| [clinical aspects of malaria]. | 1977 | 325645 | |
| chemoprophylaxis of malaria. | 1977 | 326335 | |
| sequential treatment with quinine and mefloquine or quinine and pyrimethamine-sulfadoxine for falciparum malaria. | patients with falciparum malaria were studied in thailand, an area of known chloroquine resistance. the patients were unselected and some had severe malaria, and they were randomly assigned to one of two sequential regimes. a short course of quinine (average 4 doses, equivalent to 2 g base) followed by a single dose of pyrimethamine-sulfadoxine (fansidar) cured 92% of patients (36 out of 39), while a short course of quinine followed by a single 1-5-dose of mefloquine cured all of the 35 patients ... | 1977 | 326337 |
| [a patient with high fever]. | 1977 | 327338 | |
| [chloroquine resistant tropical malaria imported from surinam]. | 1977 | 327340 | |
| the treatment of severe falciparum malaria. | in severe falciparum malaria there is a pathophysiological cascade beginning with changes in the parasitized red blood cells which induce intermediate effects, in turn contributing to dysfunction of several organs. a low serum albumin is a common but often unrecognized finding which may contribute to oedema especially in the lung and brain. the only irreversible complication in falciparum malaria is the acute respiratory distress syndrome, manifested by cyanosis and rapid breathing, basically di ... | 1977 | 339421 |
| malaria field studies in a high-incidence coastal area of el salvador, c.a. | a three-year investigation was made of the incidence patterns and characteristics of malaria in a small high-incidence coastal area of el salvador with a resident population of about 6,000 persons and a migrant population of 3,000 to 4,000 others. it found a significant increase in the incidence of plasmodium falciparum cases during the three-year period, combined with relative stability in the annual number of plasmodium vivax cases. a close correlation was observed between the seasonal occuren ... | 1977 | 328096 |
| malaria and hereditary ovalocytosis. | hereditary ovalocytosis in papua new guinea is restricted to areas of endemic malaria and may confer increased resistance to the disease. the incidence of malaria was investigated in 1616 melanesiams of known red cell morphology and severity of infection determined in a smaller subsample. ovalocytics tended to be more resistant to severe malarial infections than normocytics. the ratio of parasitaemia in 112 ovalocytics compared with 741 normocytic children was 1.05 for p. falciparum; 0.90 for p. ... | 1977 | 328370 |
| cerebral malaria. | cerebral malaria is an unusual and treatable cause of stupor and coma, and it can present suddenly in a healthy person. it is diagnosed by finding parasites on a blood smear and is treated either with chloroquine or with quinine, pyrimethamine, and sulfadiazine. | 1977 | 328970 |
| in vivo and in vitro studies of chloroquine-resistant malaria in thailand. | fourteen patients infected with falciparum malaria admitted to the hospital for tropical diseases in bangkok, faculty of tropical medicine, mahidol university, were studied. in vivo and in vitro methods were used to compare the effects of chloroquine on plasmodium falciparum. the results showed that ri in vivo corresponded to samples containing chloroquine base 2.5-3.5 millimicromoles per ml of blood in vitro and rii in vivo corresponded to samples with chloroquine base of 4.0 millimicromoles pe ... | 1977 | 339855 |
| exotic diseases. ounce of prevention or pound of cure? | with the growth of international travel, exotic diseases have assumed increasing importance to the physician. they can be effectively prevented by the use of commonsense measures. the physician should be prepared to offer advice on food, drink, and use of prophylactid drugs and to give needed immunizations to patients planning to travel. the biggest pitfall in diagnosis of exotic disease is failure to connect a history of travel with the signs and symptoms. an answer to the simple question, "whe ... | 1977 | 142245 |
| cultivation of plasmodium falciparum. | 1977 | 324435 | |
| evidence for differences in erythrocyte surface receptors for the malarial parasites, plasmodium falciparum and plasmodium knowlesi. | human erythrocytes lacking various blood group determinants were susceptible to invasion by plasmodium falciparum including duffy-negative erythrocytes that are refractory to invasion by plasmodium knowlesi. erythrocytes treated with trypsin or neuraminidase had reduced susceptibility of p. falciparum and normal susceptibility to p. knowlesi. chymotrypsin treatment (0.1 mg/ml) blocked invasion only by p. knowlesi. the differential effect of enzymatic cleavage of determinats from the erythrocyte ... | 1977 | 327014 |
| [relations between malaria and burkitt's lymphoma]. | malaria, especially forest malaria, is the environmental factor which creates endemic conditions for the esptein-barr virus related burkitt's lymphoma. the plasmodium seems active through a mitogenic factor rather than through the so often invoked immunological depresssion. | 1977 | 208788 |
| the prevention and treatment of malaria. | 1977 | 329080 | |
| malaria along the southernmost fringe of its distribution in africa: epidemiology and control. | after more than thirty years of malaria control in northern transvaal with residual insecticides, malaria prevalence has been reduced to a low level. however, low-grade transmission of plasmodium falciparum continues, with periodic focal outbreaks after abnormally high rainfall. from october 1973 to september 1976, the operational and epidemiological factors involved in this residual transmission were studied in over 17 000 people of an area of northern transvaal. incidence surveys based on the ... | 1977 | 330017 |
| [an entomologic method for the evaluation of the preventive measures used in the campaigns of malaria control]. | 1977 | 330300 | |
| biochemical markers for strain differentiation in malarial parasites. | genetic differences between micro-organisms can be identified by studying variations in enzyme forms and dna characteristics. enzyme electrophoresis has revealed considerable genetic diversity in populations of malarial parasites and has enabled populations reproductively isolated from one another to be identified. studies on rodent malarial parasites from four regions of africa have shown that each species and subspecies can be distinguished by its pattern of enzyme forms. in subspecies in whic ... | 1977 | 303952 |
| alterations of human serum proteins and other biochemical parameters after five to ten days of untreated acute falciparum malaria. | untreated malaria for more than 4 days in eleven patients decreased significantly prealbumin, transferrin levels and increased sgot activity when compared with a control group and a group of 10 malaria patients who were admitted to the hospital at an earlier stage of the infection. total protein was significantly lower in the group of patients admitted after five to ten days to hospital compared with the control group. in all malaria patients independent of the duration of the acute infection th ... | 1977 | 333673 |