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killing in vitro of trypanosoma cruzi by macrophages from mice immunized with t. cruzi or bcg, and absence of cross-immunity on challege in vivo.peritoneal macrophages from t. cruzi-immune mice were resistant to infection in vitro with culture forms of the parasite. macrophage resistance appeared in infected mice about 21 days postinfection when parasitemia was still rising. resistance in vitro was nonspecific since macrophages from bcg-immune mice were resistant to t. cruzi, and since macrophages from t. cruzi-immune mice were resistant to infection in vitro with listeria were not resistant to challenge with t. cruzi even when the par ...1975806649
rate of listeria monocytogenes shedding from frogs.leopard frogs (rana pipiens) were orally inoculated with listeria monocytogenes. most listeriae were shed 3-6 days after inoculation. the evidence indicated that the listeriae did not multiply in frogs and were unable to become established in the gastrointestinal tract.1975806711
letter: isolating listeria monocytogenes. 1975807018
[isolation of bacterial cultures from anabiosis]. 1975807022
incidence of listeria monocytogenes in nature.during a research project on the occurrence of listeria monocytogenes 194 strains were isolated in southern west germany during the years 1972 to 1974:154 from soil and plant samples (20.3%), 16 from feces of deer and stag (15.7%), 9 from old moldy fodder and wildlife feeding grounds (27.2%), and 8 from birds (17.3%). the highest number of isolates was obtained from uncultivated fields. the beta-hemolytic serovars 1/2b and 4b were were predominant; other serovars (some of them identified for the ...1975807164
phagocytosis and intracellular killing of staphylococcus aureus by normal mouse peritoneal macrophages.although staphylococcus aureus is incapable of intracellular multiplication in cultured mouse peritoneal macrophages, it is killed at a much slower rate than the avirulent staphylococcus epidermidis. in addition to the presence of capsular material which inhibits phagocytosis of specific strains of s. aureus, the data show that a number of cellular and environmental factors affect the functional capacities of mononuclear phagocytic cells. the data obtained by varying the initial level of infecti ...1975807524
listeria monocytogenes infection in nude mice.as compared to phenotypically normal (nu/+)nmri mice showing the typical course of an experimental listeric infection, that of congenitally hypothymic (nude, nu/nu)nmri mice was found to be characterized from the outset bya chronic trend. during the early phase of the infection, significantly reduced numbers of listeria monocytogenes were observed in the spleens of nude mice.1975807526
activated macrophages in congenitally athymic "nude mice" and in lethally irradiate mice.resistance to the facultative intracellular bacteria, brucella abortus and listeria monocytogenes, is principally the result of acquisition of enhanced antibacterial activity by host macrophages, probably in response to lymphokines released by t lymphocytes. however, the present paper describes a surprisingly high resistance on the part of both congenitally athymic "nude" mice and of lethally irradiated mice compared with normal controls. this enhanced bactericidal activity was evident 24 hr aft ...1975807647
specific detection and semiquantitation of micro-organisms in tissue by nucleic acidhybridization. i. characterization of the method and application to model systems.on the basis of circumstantial evidence, a number of human diseases have been postulated to result from the presence of occult infection. to investigate this problem amethod of specifically detecting and semiquantitaing trace quantities of bacterial dna in infected tissue has been devised. it is based on rna-dna hybridization using radiolabeled rnacomplementary to the dna of the organism being sought. the characteristics of the reaction are shown to conform to those expected for rna-dna hybri ...1975807659
listeria monocytogenes isolated from wapiti (cervus canadensis roosevelti).serotypes 1 and 4 listeria monocytogenes were isolated from 14 of 72 wapiti among four of five herds studied in northwestern california. more isolations of listeria were made during the summer months than during the other months of the study from one of the herds. the pathogenicity of the strains varied with their ability to ferment xylose and rhamnose.1975807750
listeria monocytogenes septicemia in pregnancy.a case of listeria monocyto-enes septicemia in a patient with a poor reproductive history is presented. the clinical aspects and implications of this infectious disease during pregnancy are discussed, and the role of listeria as a cause of recurrent pregnancy wastage is summarized.1975807894
[diagnosis of listeria monocytogenes by immunofluorescence].for precision of bacteriological diagnosis of listeria monocytogenes (l. m.) the immune fluorescent technique (ift) was assessed. on using the described immunization pattern high titres of specific antibodies were obtained from the immunized rabbits. the obtained hyperimmune sera yielded very good results when used in ift, and they were suitable for conjugate production. by means of ift l.m. was demonstrated from cultures, organ replicas and tissue sections of experimentally infected rabbits. th ...1975808008
effect of corynebacterium parvum on the course of a listeria monocytogenes infection in normal and congenitally athymic (nude) mice.spleen counts of listeria monocytogenes in normal mice challenged with various numbers of organisms were generally lower in mice injected 3 days previously with killed corynebacterium parvum. this increased resistance was unexpected since c. parvum generally inhibits t cell-mediated immunity, the functional immunity against listeria being t cell-dependent. the inhibitory effect on t cells seemed to be compensated by the stimulatory effect of c. parvum on macrophages. therefore, the experiments w ...1975808049
interrelations between mammals and pathogens of some bacterial diseases.various interrelations of mammals with some bacterial pathogens are analyzed. plaque and tularemia are the most thoroughly investigated infectious diseases in this respect. the importance of a different degree of susceptibility and sensitivity to infection for its development in mammalian reservoirs is underlined.1975808461
cytotoxicity mediated by soluble macrophage product(s).the soluble macrophage product(s) released by nonimmune mouse peritoneal macrophages exposed to endotoxin or from listeria-immune macrophages after incubation with specific antigen mediated cytotoxic activity against malignant cell types and, to a lesser extent, against normal cells. only undiluted supernatants from nonimmune or listeria-immune macrophages cultured with medium 199 alone exerted some degree of cytotoxicity on the different target cell types tested. the macrophage product(s) retai ...1975808640
listeria monocytogenes meningitis in a transplant recipient. 1975808652
[listeria excreters and their epidemiological significance (author's transl)].by using the best bacteriological methods of investigation and reading techniques we were able to discover 82 excreters from stool samples of 841 persons and to culture 113 listeria monocytogenes strains of different serotypes (1/2a, 4a, 4b, 4ab). following up several excreters over a longer time (1 1/2 years) revealed periods with positive and negative results. strains of listeria isolated from the stool samples of pregnant women have a particular significance and act as pointers to virulence. ...1975808708
intracellular killing of listeria monocytogenes by activated macrophages (mackaness system) is due to antibiotic. 1975808734
corynebacterium aquaticum septicemia. characterization of the microorganisms.an 85-year-old woman with the diagnosis of diabetic ketoacidosis developed septicemia during hospitalization. cultures of the patient's blood revealed the presence of gram-variable coccobacilli, later identified as corynebacterium aquaticum. the microorganisms grew aerobically on blood agar plates after incubation overnight. the colonies were convex, non-hemolytic and slightly yellow-pigmented. no growth was observed on macconkey and endo agar plates. the organisms were catalase-positive, oxidas ...1975808959
intermittent neutrophil-monocyte bactericidal defects in a patient with sarcoidosis.reccurrent abnormalities of polymorphonuclear leukocyte and monocyte bactericidal activity were demonstrated in a patient with sarcoidosis. defective function occurred during hypercalcemia complicating recovery from listeria meningitis, and during separate, unrelated episodes of erythema nodosum, staphylococcal cellulitis, and pneumococcal pneumonia. leukocyte morphology, oxidative metabolism, degranulation, and content of myeloperoxidase and lysozyme were normal, but low leukocyte alkaline phos ...1975808991
infections associated with ovine perinatal mortality in victoria.the occurrence of infections associated with perinatal mortality was investigated. in 1970, carcasses from 94 flocks distributed throughout victoria were examined by microbiological and histopathological techniques. carcasses from 4 of the same flocks were similarly examined in 1971. widespread occurrence of listeria monocytogenes and campylobacter fetus was demonstrated with l. monocytogenes being recognised in 25% of the flocks examined. no other bacterial pathogens commonly associated with ov ...1975809028
perinatal lamb mortality in western australia. 6. listeric infection.listeric abortion was diagnosed in sheep on 14 occasions between 1963-65, and 4 of these were associated with other major abortion pathogens. except for infection in one district, the outbreaks were scattered sporadically over the southern agricultural area. the diagnosis in 1963 was the first time listeriosis had been found in animals or man in western australia. l. monocytogenes was readily recovered in pure culture from all organs and sites cultured. all the strains were serotype 5 ivanov, wi ...1975809029
listeria as a cause of abortion and neonatal mortality in sheep. 1975809030
effect macrophage activation on infection with treponema pallidum.infection of rabbits with treponema pallidum induces nonspecific acquired cellular resistance (acr) to listeria monocytogenes. this resistance can be adoptively transferred using thymus-dependent lymphocytes. since infections that induce acr are usually brought under control by cellular mechanisms, we sought to determine whether induction of acr in rabbits stimulates resistance to challenge with t. pallidum. when bcg-infected rabbits which suppressed the growth of listeria were challenged intrav ...1975809355
blastogenesis as an in vitro correlate of delayed hypersensitivity in guinea pigs infected with listeria monocytogenes.randomly bred guinea pigs of both sexes were injected intracardially with one-half a 50% lethal dose of listeria monocytogenes. when these animals were skin tested with 30 mug of a water-soluble extract of sonically disrupted listeria, animals had uniformly detectable levels of delayed-type hypersensitivity (dth) 6 days after infection. histological examination of skin test reaction sites, after fixation in helly fixative and giemsa staining, revealed a classical tuberculin-type infiltrate consi ...1975809361
perinatal listeric septicemia in a celebese black ape.perinatal listeric septicemia was diagnosed in a still-born celebese black ape (macaca niger). the disease was characterized by prominent focal hepatic necrosis and a diffuse, acute, fibrinopurulent placentitis. small, gram-positive rods were demonstrable in sections of the placenta and in the liver and lungs of the fetus. listeria monocytogenes 1a was isolated from the liver of the fetus.1975809391
immunity to toxoplasma gondii induced in vitro in non-immune mouse macrophages with specifically immune lymphocytes.male and female cba mice were used to study in vitro the mechanisms involved in the development and expression of cellular immunity to toxoplasma infection. the lag phase preceding toxoplasma division was delayed in nonimmune macrophages obtained from peritoneal cavities stimulated with thioglycollate. specific anti-toxoplasma activity was conferred on nonimmune macrophages incubated with toxoplasma-immune spleen lymphocytes and soluble toxoplasma antigen. treatment of immune spleen cell populat ...1975809507
[listeria meningoencephalitis (3 cases)]. 1975809824
[listeriosis during pregnancy and excretion of listeria by laboratory workers (author's transl)].the occurence of listeriosis during pregnancy in a medical technician and listeriosis in a neonate gave rise to an investigation of all laboratory workers being employed in this medical institute for the excretion of l.m. there had been no work with listeria or material containing listeria. in 11 out of 12 female employees, excretion of l.m. was observed over an extended period of time, also with a change of serotypes (see table 1 or fig. 1). it was supposed that frequent contact with laboratory ...1975809945
further observations of changed growth of listeria monocytogenes on salt agar.the changes produced in listeria monocytogenes grown on salt media were studied. high concentration of nacl is really a possible inducer of filamentation as well as of spheroplasting in l. m. it acts by inhibiting the cell division of these bacteria.1975809946
new selective media of rivanol content for listeria monocytogenes cultures. 1975809949
nature of "memory" in t-cell-mediated antibacterial immunity: anamnestic production of mediator t cells.mice that survived an immunizing infection with listeria monocytogenes remained specifically resistant to lethal secondary infection for several months. this acquired, long-lived state of resistance was not dependent on activated macrophages that remained after the primary response. it depended, instead, on an acquired long-lived capacity on the part of immunized mice for generating mediator t cells faster and in larger numbers than normal mice. the number of mediator t cells generated in respon ...1975811558
nature of "memory" in t-cell mediated antibacterial immunity: cellular parameters that distinguish between the active immune response and a state of "memory".immunizing infection in mice with listeria monocytogenes resulted in the generation of two distinct states of immunological reactivity. there was generated (i) a short-lived state of active immunity that functioned to urgently eliminate the infection organism from the tissues and (ii) a long-lives state of increased immunological potential that enabled the host to respond to seconday infection in an accelerated manner. short-lived active immunity was mediated by replicating t cells and expressed ...1975811559
dichotomy between macrophage activation and degree of protection against listeria monocytogenes and toxoplasma gondii in mice stimulated with corynebacterium parvum.in vivo and in vitro experiments were conducted to determine the effect of corynebacterium parvum treatment of mice on resistance of listeria monocytogenes and toxoplasma gondii. intravenous immunization with c. parvum conferred transient protection against intravenous challenge with listeria or an avirulent strain of toxoplasma but did not protect against a virulent strain of toxoplasma. compared with the level of protection conferred by c. parvum, a higher degree of resistance was noted when m ...1975811563
[some properties of carrier strains of listeria monocytogenes (author's transl)].about 60 characteristics have been investigated in 7 hemolyzing and 12 nonhemolyzing strains of l. monocytogenes. from these investigations resulted inter alia that the organism grows well under strictly anaerobic conditions, esculin is split at 45 degrees c,nh3 is produced from peptone, but not from arginin, and h2s can be traced by sufficiently sensitive methods. all strains possess a lipase, muramidase, and deoxyribonuclease, the hemolytic ones only also a lecithinase. besides, the hemolytic ...1975811965
nonspecific resistance to listeria monocytogenes in mice infected and elicited with staphylococcus aureus.normal mice and mice displaying delayed hypersensitivity to staphylococcus aureus were challenged with a lethal dose of listeria monocytogenes. nonspecific antimicrobial activity was assessed by inhibition of bacterial growth in the spleen and by increased survival rates. administration of specific staphylococcal antigen prior to challenge was a prerequisite for the induction of nonspecific resistance. both the time of administering eliciting antigen and the route were important consideration fo ...1975811966
[the occurrence of listeria encephalitis in cattle in a loose housing after the use of litter, infected with listeria bacteria, from a broiler farm. to what extent do listeria bacteria occur in the gut contents of broilers (author's transl)].in a loose housing, four cows had to be slaughtered as an emergency measure within a few weeks because of symptoms of encephalitis. listeria monocytogenes of type 4 b were isolated both from the brains of these cows and from the litter previously spread in the cow stables, which was obtained from a broiler farm. at the same time an investigation of the occurrence of listeria bacteria in the faeces/gut contents of broilers was undertaken. from the contents of 2373 intestines, representing 0.1 per ...1975812205
[toxic action of listeria monocytogenes].two hoggets and 56 albino mice were used to study the effect of a water-extracted antigen of listeria monocytogenes, strains 1,4b and st. r., through freezing, thawing, shaking, and filtrating (seitz filter). a histologic examination was made of sections of the brain, lungs, heart, liver, spleen, and kidneys, stained with hematoxylin-eosin. most characteristic of the toxic effect were the necrobiotic changes in the brain and viscera as well as the histiocytic infiltrations with the formation of ...1975812254
the role of temperature factors in the epidemiology of listeriosis.a total of 5000 samples were examined for listeria monocytogenes, and 117 strains had been isolated. out of these, 36 strains were selected according to their low virulence. an increasing virulence could be observed, when they were cultured on optimal media at 4 degrees c, with inoculations at every third week. this increased virulence caused by temperature factors, can have an important role in the epidemiology of listeriosis.1975812294
isolation of listeria monocytogenes in slaughter animals and bats of togo (west africa).listeria monocytogenes was isolated from the intestinal lymph nodes of 8 out of 342 apparently healthy slaughter animals at the municipal abattoir in lome (togo) and from the faeces of 3 out of 236 bats. except two strains of serovar 4b isolated from bats, all the nine others belonged to serovar 1/2a. the positive findings of slaughter animals were made from the carcasses of 2 pigs, 5 little ruminants and 1 cattle. the findings are discussed in the light of present knowledge on the occurrence of ...1975812407
genital listeriosis (a case report). 1975812986
mechanisms of protective immunity in experimental cutaneous leishmaniasis of the guinea-pig. i. lack of effects of immune lymphocytes and of activated macrophages.leishmania enriettii is an obligatory intracellular protozoan parasite which infects guinea-pigs and resides in macrophages. subcutaneous inoculation produces a skin infection which heals spontaneously and leaves the animal immune to reinfection. experiments have been performed to explore the mechanisms of parasite destruction in the recovering and immune animal. using quantitative techniques to assess parasite survival it was found that l. enriettii is not killed in vitro in macrophages from im ...1975813928
[dynamics of multiplication and changes in the virulence of various pathogenic microorganisms in milk and milk products]. 1975814792
perinatal listeriosis: a bacteriological and serological study. 1975816738
t-cell-mediated immunity. 1975817669
cortisone-resistant effector t cells in acute lymphocytic choriomeningitis and listeria monocytogenes infection of mice.sensitized t cells in both lymphocytic choriomeningitis (lcm) and listeriosis are apparently unaffected by treatment of mice with cortisone acetate. cortisone-resistant immune t cells readily transfer acute, fatal lcm or protection against l. monocytogenes infection. treatment of recipient mice with cortisone, however, impairs t cell-dependent effector mechanisms (i.e. macrophages) in listeriosis, but has no effect on induction of lcm. acute lcm may thus represent a t cell-mediated pathological ...1975820320
purification and characterization of two bacteriocins from streptococcus faecium.two bacteriocins were found in the supernatant fluid and in an extract of streptococcus faecium strain ei. the small soluble enterocin eia represented more than 90% of the total activity in the supernatant fluid, and was purified 400-fold by ammonium sulphate fractionation, gel filtration on sephadex g-75 and chromatography on deae-cellulose. enterocin eib, with a particle weight greater than 4 x 10(6), was the predominant type in the extract. it was released in appreciable quantities after brea ...19751097585
[isolation and classification of listeria monocytogenes from sewage water]. 1975822259
listeria monocytogenes: faecal carriers and perinatal mortality. 1975825700
macrophage inhibiting activity in serum and central lymph of listeria-immune mice.serum and central lymph from mice immunized with live listeria monocytogenes six days previously and boostered four hours before collection exerted significant inhibition of macrophage migration in vitro. it is concluded that lymphokines or lymphokine-like products of the cellular immune reaction are released in vivo and are possibly instrumental in the generation of acquired cellular antibacterial immunity.1975829904
[pseudomonas aeruginosa in the feces of healthy man (author's transl)].by means of a selective medium described for the isolation of listeria monocytogenes (nalidixic acid - trypaflavin - serum agar) 18 strains of ps. aeruginosa have been obtained from the feces of 344 healthy adults (5.2%).1975816111
[the effect of an inflammatory reaction on the resistance of mice to infection by listeria monocytogenes and salmonella typhimurium].following subcutaneous acute inflammatory reactions in mice, the blood clearance of virulent salmonella typhimurium was enhanced and the multiplication of listeria monocytogenes in spleen and liver was decreased.1975816520
[laboratory diagnosis of listeriosis in the light of 3 cases]. 1976816635
septicemia in renal transplant recipients.thirty-six renal transplant recipients with 47 episodes of septicemia were studied carefully at the bedside, in the laboratory, and, all too frequently, at autopsy. gram-negative bacilli were the pathogens most commonly responsible, folloed in order of frequency by gram-positive cocci, polymicrobic etiologic agents, listeria monocytogenes, and fungi. infections of the transplant site (urinary tract or transplant wounds) caused septicemia in 51% of the cases. other portals of entry included the l ...1976790736
enhanced toxicity for mice of combinations of bacterial lipopolysaccharide and vincristine.sublethal doses of vincristine (vnc) and bacterial lipopolysaccharide (lps) administered simultaneously to adult male mice resulted in markedly enhanced mortality. all of 10 strains of pseudomonas aeruginosa tested, 4 of 7 strains of bacteroides, and 6 of 10 strains of listeria monocytogenes were able to substitute for purified lps in enhancing mortality in vnc-treated mice. inoculation of mice with each of 10 strains of pseudomonas, each of 7 strains of bacteroides, and about half of the 10 str ...1976949180
macrophage function and host resistance against infection with toxoplasma gondii.the role of macrophages on the course of an infection with toxoplasma gondii has been examined. stimulation of macrophage function by killed bordetella pertussis cells did not show any beneficial effect as an increased susceptibility became apparent. the functional blockade of macrophages by dextran sulfate or carbon particles did not result in a higher susceptibility of mice to the lethal primary infection with t. gondii. thus in vivo macrophages apparently do not play an essential role as effe ...1976974901
morphology and time course of experimental listeriosis in nude mice.experimental listeriosis in phenotypically normal (nu/+) euthymic nmri mice has a characteristic morphology and short-term course. in contrast, listeric infection in congenitally dysthymic nude (nu/nu) mice does not proceed in clear-cut phases, develops more slowly, displays a chronic tendency from the beginning, and shows a considerably different morphology. the inability of nude mice to effectively control and terminate infection by listeria monocytogenes obviously results from the lack of t ...19761085754
[the significance of the t-cell-mediated reaction in the defence against infection with listeria monocytogenes (proceedings)]. 19761086559
[immunologically induced improvement of killing performance of peritoneal macrophages against listeria monocytogenes in the mouse (proceedings)]. 19761086560
listeria monocytogenes in "oven-ready" poultry.listeria monocytogenes was isolated from 10 out of 68 "oven-ready" poultry (ie, 14-7 per cent) purchased at 26 different shops and supermarkets. the organisms belonged to type 4 and 1/2; from one chicken both serotypes were isolated.1976826007
acquired resistance against listeria monocytogenes in red mice and cf1 mice immunized with strains of bcg or mycobacterium tuberculosis.groups of red mice and cf1 mice immunized intravenously with varying doses of a weak or a strong strain of bcg or a strain of mycobacterium tuberculosis were challenged 3 weeks after immunization with 0.1 or 0.2 ml 10(-2) listeria monocytogenes injected intravenously, simultaneously with a non-immunized control group. the acquired resistance was determined on the basis of the number of survivors and the survival times of the animals that died spontaneously. in the red mice, the strong bcg strain ...1976826109
critical review of previously reported animal studies of tumor immunotherapy with nonspecific immunostimulants. 1976826208
[effect of the lipid fraction of listeria monocytogenes cells on the immune response of irradiated mice. i. effect of lipids administered prior to irradiation]. 1976826740
[effect of the lipid fraction of listeria monocytogenes cells on the immune response of irradiated mice. ii. effect of lipids administered following irradiation]. 1976826741
monocyte preparation from blood. 1976826759
[biological properties of erysipelothrix phages isolated from lysogenic cultures]. 1976827193
acquired cellular resistance following transfer of lymphocytes from mice infected repeatedly with staphylococcus aureus. 1976827335
contributions to further sero-variants of listeria monocytogenes.the authors report on the isolation of 13 listeria monocytogenes strains of healthy human subjects which, within serogroup 4, contain at least four variants of known listeria antigens, but wound not fit into the grouping system that has been in use.1976827878
listeria-encefalitis in cows through litter from a broiler-farm.in a loose-housed herd four cows are emergency-slaughtered, within some weeks, because of symptoms of encefalitis. from the brains of these cows, as well as from the litter, coming from broilers, that had been put in the cow-stables before, listeria monocytogenes type 4b has been isolated. at the same time an investigation was made from faeces/intestinal contents of broilers. out of the contents of 2.373 intestines, 1% of about 2.300.000 broilers ready for use, coming from 146 farms, 4.1% l.mono ...1976828366
ultrastructural changes induced by freezing and thawing in listeria monocytogenes (transmission and scanning electron microscopy). 1976828490
[listeria meningitis in children]. 1976828896
effect of pulmonary irradiation from inhaled 90y on immunity to listeria monocytogenes in mice. 1976829554
[further study of the antibody adsorption test for the purpose of increasing the specificity of listeriosis serodiagnosis].in testing the specificity of interaction in the agglutination reaction with listeria antigens of 191 sera of healthy persons with the aid of adsorption with staphylococcus, enterococcus and listeria a positive result was obtained in 56.5% of cases (108 sera); the higher the serum titres--the more of them reacted specifically (31.7% at the 1 : 40 titre; 83.3--100% at the 1 : 160--1 : 320 titres).1976822660
serum levels of progesterone, estradiol, and hydrocortisone in ewes after abortion due to listeria monocytogenes type 5.estradiol, progesterone, and hydrocortisone were measured by radioimmunoassay in peripheral serum of pregnant ewes infected with listeria monocytogenes type 5 and in normal pregnant controls. progesterone had decreased in both groups at abortion or parturition. estradiol and hydrocortisone of control ewes had increased at parturition. in infected ewes, the serum hydrocortisone value was high for 3 days after inoculation, but it returned to preinoculation levels for the remainder of gestation. se ...1976822762
letter: prevalence of listeria monocytogenes in the newborn. 1976822787
role of lymphocytes in cellular resistance in infection. 1976822980
effect of tilorone on susceptibility of mice to primary or secondary infection with listeria monocytogenes.subcutaneous administration of the drug tilorone did not increase the susceptibility of cd-1 male mice to intravenous or intraperitoneal infection with an alpha-toxin-deficient mutant of the smith diffuse strain strain of staphylococcus aureus. in contrast, a single injection of this drug greatly increased the susceptibility of mice to an intravenous or an intraperitoneal infection with listeria monocytogenes, an intracellular parasite. the effects of tilorone, which were maximal when the drug w ...1976823106
the listeria monocytogenes infection. a case report and review of the literature with special reference to the cases in maine. 1976823286
[comparative studies on the effectiveness of 2 frequently-used elective culture media for enterococci]. 1976823722
acquired resistance of bcg-vaccinated red mice to infection with listeria monocytogenes.infection experiments have shown that red mice, belonging to the vole family, could be infected with listeria monocytogenes and that they were almost as susceptible to intravenous infection as cf1 mice. vaccination of red mice with bcg induced a resistance which could be demonstrated by prologation of the survival time of the animals after challenge with listeria. the resistance was greatest in the second and third week after vaccination and was considerably higher after intravenous injection of ...1976823794
activation of guinea pig macrophages by cell walls of mycobacterium bovis, strain bcg. 1976824056
[listeriosis]. 1976824387
the autoinhibition activity of some microbial species.studies revealed that during the process of their reproduction some microorganisms produce substances inhibiting the development of the own populations. a method was developed to establish the phenomenon, distinguished by its simple application and dependable results. the phenomenon was noted with the species staphylococcus, l. monocytogenes, salmonealla, and e. coli, and was lacking in p. multocida, brucella, ery. rhusiopathiae, bac. anthracis, and bac. subtilis. it was found that the agent cap ...1976824897
certain chemical and biological properties of phenol extracts from listeria monocytogenes.a toxic component obtained by phenol extraction of listeria monocytogenes 9-125 was found to have a molecular weight of about 2 x 10(6). this material was composed of carbohydrate, protein, lipid, phosphorus, and a component resembling 2-keto-3-deoxyoctanate. infrared spectrums indicated that similarities existed between this material and salmonella abortus-equi lipopolysaccharide. mild acid hydrolysis produced water-soluble and water-insoluble fractions. sheep erythrocytes sensitized with aqueo ...1976824986
[immunological responsiveness in c57bl/6 mice during the growth of a tumoural graft: the lewis' lung carcinoma (author's transl)].using antibody and delayed type hypersensitivity responses to sheep red blood cells, immunological responsiveness was studied during the course of 3ll tumor growth. acquired specific resistance to listeria monocytogenes of tumor bearing mice was also investigated. experimental results obtained, showed that the ability of 3ll bearing mice to establish a specific immune response is not markedly impaired.1976825018
resistance to tumor growth mediated by listeria monocytogenes: collaborative and suppressive macrophage-lymphocyte interactions in vitro.spleen (sc) and peritoneal cells (pc) from c57bl/6 mice immune to listeria monocytogenes (lm) have a marked cytotoxic effect on the in vitro growth of b-16 melanoma. cytotoxicity to b-16 is mediated by the interacting semsitized thymus-derived (t) lymphocytes and macrophages (mchi) or adherent cells. separation of immune sc or pc into their adherent and nonadherent components, depletion of the adnerent cells or elimination of the theata-bearing cells from an enriched t cell population all result ...1976825574
subversion of host defense mechanisms by murine tumors. i. a circulating factor that suppresses macrophage-mediated resistance to infection.the subcutaneous injection of cells of any one of five unselected murine tumors resulted very rapidly in the liberation into the circulation of a small molecular weight factor that severely impaired the capacity of the host to resist experimental infection with listeria monocytogenes and yersinia enterocolitica. it was found that the factor appeared in blood within 8 h of injecting tumor cells subcutaneously. that it possessed potent physiological activity was evidenced by the demonstration that ...19761249520
[possible relationship between bacterial surface structures, immune-adherence, chemotaxis and phagocytosis (author's transl)].in the present study we attempted to determine the relationship between bacterial surface structures, immune adherence, chemotaxis and phagocytosis. as shown in table 1 encapsulated bacteria (klebsiella ozanae, k. pneumoniae, pasteurella multocida, streptococcus pneumoniae), mycoplasma pneumoniae and m. fermentans had a much lower immune adherence-activity than non-encapsulated bacteria (bacillus cereus, brucella abortus, erysipelothrix insidiosa, escherichia coli, listeria monocytogenes, pseudo ...19761258564
[listeriosis in a riding-horse stock]. 1976820329
the mediator of cellular immunity. xi. origin and development of mif producing lymphocytes. 1976820434
acute listeria monocytogenes osteomyelitis.the presentation and management of a case of acute listeria monocytogenes osteomyelitis in a lady with acute lymphoblastic leukaemia are described. the literature on listeria infection is briefly reviewed, and the importance of scrutinizing diphtheroid-like isolates in the laboratory is stressed.1976820648
maternal listeria monocytogenes septicemia with sparing of the fetus.a case of maternal listeria monocytogenes septicemia at 19 week's gestation is presented. successful treatment of the mother with ampicillin resulted in remission of maternal symptoms and subsequent term delivery of an unaffected infant, indicating fetal disease is not an inevitable consequence of maternal listeria sepsis.1976821025
[histological study of ceratophyllus consimilis wagn. fleas infected with the causative agent of listeriosis (listeria monocytogenes)].histological studies have shown that in experimentally infected fleas (c. consimilis) listeria are preserved in the alimentary canal. in infected individuals microbes occur along the whole intestine, from oesophagus to the rectum but most often they are recorded from the mid-gut and proventriculus. listeria are able to penetrate into its muscular tissue and in some cases enter the body cavity of the insect. the finding of listeria in the oesophagus confirms the possibility of the transmission of ...1976821031
stimulation of the non-specific resistance by corynebacterium parvum and bacillus calmette guérin.the effect of pretreatment of intravenously administered killed corynebacterium parvum (cp) and living bcg was studied in various model systems. both vaccines caused an increased resistance to listeria monocytogenes, indicating macrophage activation. only cp exerted a suppressive effect on t-cell-mediated immunological phenomena (skin allograft survival; antibody production to tetanus toxoid; expulsion of adult t. spiralis worms from intestine). results of experiments with congenitally athymic ( ...1976821172
[some biochemical studies of listeria monocytogenes strains].a total of 231 strains of listeria organisms have been isolated during the last 14 years from adult sheep, lambs, fetuses, and ensilaged forage. their differentiation have shown that 67 of them belong to the 1 st serotype, 77 -- to 4 c, and 26 have been determined as strains of the 5th serotype. the biochemical study on 170 of the strains have revealed that: more of them, belong to the 1 st, 4 c, and 5 th serotype break down dextrose, trehalose, levulose, salycin, esculin, ramnose, and glycerin. ...1976821209
[detection of h-antibodies in the diagnosis of listeriosis].the technique of h-antibodies determination in serodiagnosis of listeriosis used at present is capable of detection not only h-antibodies but also flagellar somatic antibodies in the sera. an attempt was made to increase the specificity of h-agglutinins. an experience in the preparation of pure h-antigen is described. however, it is impossible to detect positive h-agglutination either with the aid of a mixture of flagellae and latex or with pure h-antigen. after determination of h-antigen by the ...1976821279
effect of pretreatment with bacillus calmette-guerin on the course of a listeria monocytogenes infection in normal and congenitally athymic (nude) mice.the effect of pretreatment with bcg on the course of a listeria monomcytogenes infection was studied in nu/nu mice and in their heterozygous littermates (+/nu). first, evidence was presented that the nu/nu mice used lacked functional t cells, since bcg treatment resulted only in skin reactivity to tuberculin in +/nu mice and not in nu/nu mice. acquired resistance to listeria (based on lower spleen counts) was only obtained in bcg pretreated +/nu mice. evidence was presented that bcg pretreatment ...1976821508
listeria cell wall fraction. characterization of in vitro adjuvant activity.we have previously described a crude cell wall fraction of listeria monocytogenes (lcwf) which induces resistance to listeria infection in mice, is a murine b-cell mitogen and is an immunological adjuvant. data reported here show that lcwf, which is effective over a wide dose range, exerts its adjuvant action on early events in the induction of an immune response. moreover, lcwf stimulates nonadherent cells to respond to sheep red cells when adherent cells are severely depleted or absent, sugges ...1976821854
antimicrobial activity of econazole and miconazole in vitro and in experimental candidiasis and aspergillosis.the antibacterial and antimycotic activity of econazole base, an imidazole derivative, was examined in vitro and in experimental infections of mice. comparative minimal inhibitory concentration (mic) determinations indicate econazole as well as miconazole to be of moderate activity against gram-positive bacteria (mics: 0.78-25mug/ml) and yeasts (mics: 1.56-25 mug/ml). against filamentous fungi, econazole exhibits better in vitro activity than miconazole and - with the exception of rhizopus oryza ...1976817875
bactericidal properties of human cell-free lymph.the bactericidal properties of human cell-free lymph have been investigated. gram-negative and gram-positive bacteria are susceptible to the killing action of lymph fluid. the colony-forming ability of escherichia coli and bacillus subtilis was reduced by 3 logs after 20 min of incubation with 10% (vol/vol) lymph. salmonella and listeria were less susceptible to killing. the presence of multiple killing factors in lymph showing different specificities for different bacterial cells was demonstrat ...1976818015
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