Publications

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nucleic acid homology as a measure of genetic compatibility among streptococci and a strain of diplococcus pneumoniae. 19704392941
effects of prototype space diet on the bacterial fecal flora of humans. 19704393064
[gastric microbial flora and its sensitivity to antibiotics following a short-time use of the tetracyclines morphocycline and glycocycline]. 19704395425
the proteins in membrane and cytoplasmic ribosomes of streptococcus fecalis. an extra protein in the 50-s subparticles of cytoplasmic ribosomes. 19704985343
dissociation of an autolytic enzyme-cell wall complex by treatment with unusually high concentrations of salt. 19704985440
inhibition of methotrexate resistant mutant of streptococcus faecalis by analogs of purine and pyrimidine. 19704985487
pathogenic bacteria and their sensitivity patterns in a hospital population of geriatric patients with chronic disease. 19704985072
the disinfection of swimming pool water. ii. a field study of the disinfection of public swimming pools. 19704985286
intestinal flora of folate-deficient mice. 19704984450
pronase and "immunogenic rna". inactivation of mouse anti-phage antibody with pronase. 19704984558
nalidixic acid cetrimide agar. a new selective plating medium for the selective isolation of pseudomonas aeruginosa. 19704984597
[antibacterial activity of streptococcus faecalis]. 19704984672
entropy of microbial growth. 19704984868
effect of bacteriocin from streptococcus faecalis on microbial l-forms. 19704984336
extrusion of sodium and hydrogen ions as the primary process in potassium ion accumulation by streptococcus faecalis.glycolyzing cells of streptococcus faecalis accumulate k(+) with concurrent extrusion of equivalent amounts of h(+) and na(+). an attempt was made to clarify the retionship between the movements of na(+) and k(+). sodium was displaced from cells glycolyzing in the presence of ammonia, diethylamine, tris(hydroxymethyl)aminomethane, and other nitrogenous cations; by contrast, k(+) was completely retained. accumulation of k(+) by heterologous exchange for na(+) was not inhibited by antibiotics whic ...19704983644
model for cell wall growth of streptococcus faecalis.in exponentially growing and dividing cells of streptococcus faecalis, it is proposed that the leading edge of the annularly closing cross wall is the point of extension for both cross wall and peripheral wall. peripheral wall extension is thought to be produced by the separation or splitting of the cross wall at its junction with peripheral wall. this results in the pushing of the equatorial wall bands, found on s. faecalis walls, to subsequatorial positions. these bands therefore mark the sepa ...19704984078
bacteriologic studies on wasting disease induced by neonatal thymectomy. 19704983533
[the effect of ascorbic acid on the results of the estimation of folic acid in food products]. 19704987181
bacteriuria and arterial hypertension in old age. 19704987210
early changes in the ultrastructure of streptococcus faecalis after amino acid starvation.thin sections of streptococcus faecalis (atcc 9790) starved of one essential amino acid (threonine or valine) initially show rapid increases in (i) cell wall thickness, (ii) the apparent size of the central nucleoid region, and (iii) mesosomal membranes. the most rapid increases in all three variables occurred during the first 1 to 2 hr of starvation. after this initial period, the rates progressively decreased over the 20-hr observation period. during threonine starvation, the mesosomal membran ...19704987306
microbiological determination of the amino acids of xanthine oxidase. 19704987322
bacterial flora of the bovine eye with special reference to the moraxella and neisseria. 19704987567
[acute aortic insufficiency during endocarditis due to "streptococcus foecalis" in 2 patients treated by periodic hemodialysis]. 19704987604
exchange between parenteral and tissue folate in man. 19704987890
urinary excretion of folic acid activity in man. 19704987973
in-vitro comparison of erythromycin, lincomycin, and clindamycin.the in-vitro antibacterial activities of erythromycin, lincomycin, and clindamycin, a new derivative of lincomycin, were compared. clindamycin was always more active than lincomycin, and was either as active as erythromycin or more so against betahaemolytic streptococci, streptococcus viridans, str. pneumoniae, and erythromycin-sensitive staphylococcus aureus. it was also fully active against most erythromycin-resistant strains of staph. aureus. on the other hand, it was somewhat less active tha ...19704988120
relationship between the location of autolysin, cell wall synthesis, and the development of resistance to cellular autolysis in streptococcus faecalis after inhibition of protein synthesis.ten minutes after inhibition of protein synthesis with chloramphenicol (cap) the ability of cells of streptococcus faecalis (atcc 9790) to autolyze decreased to less than 20% of the rate for exponential-phase cells. after threonine exhaustion, the time for a 50% drop in the rate of cellular autolysis was about 20 min. these rapid increases in resistance to cellular autolysis could not be accounted for by: (i) the relatively slow and small overall decrease in susceptibility of isolated cell walls ...19704988243
site of initiation of cellular autolysis in streptococcus faecalis as seen by electron microscopy.low concentrations of glutaraldehyde (0.1% or higher) blocked cellular and wall autolysis. the site of autolytic activity was studied by allowing cell autolysis to proceed for very short periods (0 to 15 min) before addition of glutaraldehyde. electron microscopy of ultrathin sections showed that the primary site of autolytic activity was the leading edge of the nascent cross wall. the base of the cross wall seemed more resistant than the tip. evidence supporting the involvement of autolysin act ...19704988247
effect of iron on the bactericidal proteins from rabbit polymorphonuclear leukocytes. 19704988270
[utilization of the phenomenon of spontaneous bacteriolysis for the knowledge of sanitary state of fresh and marine waters]. 19704988331
antibiotic synergism of enterococci. relation to inhibitory concentrations. 19704988356
[treatment of urinary tract infections with cephalexin an oral antibiotic of cephalosporin-group]. 19704986282
terpene compounds as drugs. 8. bacteriological and pharmacological properties of terpenyl penicillins. 19704986283
[relations between physical-chemical properties and antimicrobial effect of beta-amino-ketones. 9. cytostatics]. 19704986468
short-lived infection with enterococci of mouse oviduct following mating. 19704986480
[photochemical inactivation of folic acid in the presence of riboflavin and its inhibition by ascorbic acid]. 19704985645
preparation and activity of the 4'-thio derivatives of some 6-substituted purine nucleosides. 19704985956
rat liver glutamate formiminotransferase activity in b12 deprivation and germfree conditions. 19704985957
studies of (3h)folic acid uptake by lactobacillus casei. 19704985961
[experiences with doxycycline in microbiological routine diagnosis]. 19704986039
carbon dioxide fixation by extracts of streptococcus faecalis var. liquefaciens.extracts of cells of streptococcus faecalis var. liquefaciens strain 31 incorporated (14)co(2) into aspartate. dialyzed extracts produced radioactive oxalacetate in the absence of exogenously added glutamate and pyridoxal-5'-phosphate and produced radioactive aspartate in the presence of these components. reduced nicotinamide adenine dinucleotide or reduced nicotinamide adenine dinucleotide phosphate could not be substituted for adenosine triphosphate (atp); phosphoenolpyruvate even in the prese ...19704986758
urinary infection in two selected neonatal populations. 19704986864
plate assay methods for amino acids. 10. arginine and histidine. 19704987086
plate assay methods for amino acids. 11. further studies on lysine. 19704987087
pyelonephritis. ix. effect of enterococcal pyelonephritis on mortality in the rat. 19704987124
[in vitro effect of gentamicin on 5 bacterial species]. 19704986542
effect of ph of medium and size of inoculum on activity of antibiotics against group d streptococcus (enterococcus).seventy-one clinical isolates of 5 species of group d streptococcus (enterococcus) were tested for susceptibility to 15 antibiotics at ph 5.0, 7.4, and 8.5. penicillin g, ampicillin, cephalothin, cephaloridine, and novobiocin were considerably more active against all strains at ph 5.0 than in the more alkaline media. on the other hand, lincomycin, clindimycin, erythromycin, and gentamicin were moderately to markedly more active at ph 8.5. no important differences were noted in the susceptibility ...19704986728
[leukoencephalitis as a complication of acute purulent meningitis]. 19704988534
[dynamics of typhoid bacteria discharge in chronic carriers according to the season of the year and its significance in the epidemiology of the disease]. 19704988550
bilateral tibiotarsal fracture in a wallaby. 19704989057
osmotic fragility and mouse virulence in enterococcal l-forms. 19704989098
the fate of penicillin-damaged enterococci in the mouse kidney. 19704989099
production of extracellular proteolytic enzymes from two strains of oral streptococci. 19704988925
vitamin b6-amino acid-peptide interrelationships in streptococcus faecium 0 51. 19704988977
potentiating effect of organomercurials on bisphenols. 19704983485
enhancement of glutamic-pyruvic transaminase activity in leptospirae by addition of rabbit serum.glutamic-pyruvic transaminase (gpt) in leptospirae was shown to have an optimal temperature of 30 c and ph 8.0. it was activated by cofactor pyridoxal phosphate, similar to gpt from other sources. however, gpt in all leptospirae, such as leptospira canicola, l. icterohaemorrhagiae, l. autumnalis, and l. biflexa, evidently had less activity even when pyridoxal phosphate was present, in comparison with the cultivable spirochete reiter treponeme and streptococcus faecalis. the low level of activity ...197016557719
pyelonephritis xi. effect of growth phase of streptococcus faecalis on serum susceptibility and virulence.rapidly growing streptococcus faecalis was found to be markedly susceptible to the bactericidal activity of normal rat and rabbit sera, whereas stationary-phase organisms were resistant. in contrast, human serum killed neither phase organism. further, human serum was found to interfere with killing by rabbit serum. the serosusceptible, rapidly growing organisms were less virulent than the seroresistant, stationary-phase organisms. this was tested by production of pyelonephritis in the rat after ...197016557772
responses of the peyer's patches in germ-free mice to antigenic stimulation.lymph nodes, spleens, and peyer's patches of germ-free mice are relatively inactive. the tissues are small and contain rare, small, indistinct, germinal zones. when exposed to antigenic stimuli (salmonella paratyphi a and lymphocytic choriomeningitis virus), the tissues become larger and germinal zones appear coincident with antibodies in the blood. the peyer's patches were activated if antigen was absorbed from the intestinal lumen into the circulation but not if the antigen was administered pa ...197016557807
lysis of grouped and ungrouped streptococci by lysozyme.thirty strains of streptococci were tested for lysis with lysozyme, and 29 of these could be lysed by the following method: (i) suspension of the cells to a klett reading of 200 units (no. 42 filter) in 0.01 m tris(hydroxymethyl)aminomethane buffer, ph 8.2, after washing twice with the buffer; (ii) addition of lysozyme to a final concentration of 250 mug/ml with incubation for 60 min at 37 c; (iii) addition of sodium lauryl sulfate (sls) to a final concentration of 0.2% and incubation up to an a ...197016557878
membrane mg-(ca)-activated adenosine triphosphatase of escherichia coli: characterization in the membrane-bound and solubilized states.the membrane-associated mg(2+)-activated and ca(2+)-activated adenosine 5'-triphosphatase (ec 3.6.1.3; atpase) activities of escherichia coli were further characterized. the degree of inhibition of membrane-bound mg(2+)-(ca(2+))-atpase by a series of anions (i.e., sodium salts of nitrate, iodide, chloride, and acetate) was found to correlate with the relative chaotropic, or solubilizing, effectiveness of these anions. the enzyme was solubilized from washed membrane ghosts by treatment with 0.04% ...197016559094
urinary tract pathogens-sensitivity to trimethoprim/sulphamethoxazole.abstract the sensitivity to sulphamethizole, sulphamethoxazole (sm), trimethoprim (tmp) and the combination sm/tmp of freshly isolated urinary tract pathogens from hospital patients was studied. out of 798 strains tested primarily, 47% were found to be fully sensitive to sulphamethizole (tablet method), and 81% fully sensitive to the sm/tmp combination (disk method). out of 423 strains with reduced sensitivity to sulphamethizole, 65% were fully sensitive to sm/tmp. out of 391 strains tested seco ...197025607580
the biochemical and antimicrobial activities of phagocytizing cells. 19714395983
mechanism for regulating the distribution of glucose carbon between the embden-meyerhof and hexose-monophosphate pathways in streptococcus faecalis.glucose-adapted streptococcus faecalis produced little if any (14)co(2) from glucose-1-(14)c, although high levels of glucose-6-phosphate dehydrogenase (ec 1.1.1.49) and 6-phosphogluconate dehydrogenase (ec 1.1.1.44) were detected in cell-free extracts. metabolism of glucose through the oxidative portion of the hexose-monophosphate pathway was shown to be regulated in this organism by the specific inhibitory interaction of the embden-meyerhof intermediate, fructose-1, 6-diphosphate (fdp), with 6 ...19714396792
[laboratory findings on a combination of trimethoprim and sulfamethoxazole]. 19714396839
the occurrence of multiple glyceraldehyde-3-phosphate dehydrogenases in cariogenic streptococci. 19714397144
[lethal bacterial endocarditis of the aortic valve in the change of time (1921 to 1968)]. 19714397155
the significance of the carbohydrate constituents of bovine thrombin for the clotting activity. 19714397223
characteristics of a bacteriocin derived from streptococcus faecalis var. zymogenes antagonistic to diplococcus peumoniae.a bacteriocin-producing strain of streptococcus faecalis var. zymogenes (e-1) was isolated from clinical material (conjunctiva). the active substance differed from bacteriocins described by other investigators primarily in its spectrum of antibacterial activity, especially by its marked inhibition of diplococcus pneumoniae. the e-1 bacteriocin also inhibited nonhemolytic strains of enterococci as well as one-third of the viridans group of streptococcal strains investigated. the degree of inhibit ...19714398532
quantitative studies on the salivary flora.in a quantitative bacteriological study of the salivary flora from 50 children the following aerobic organisms were identified and enumerated: alpha-haemolytic streptococci, beta-haemolytic streptococci, streptococcus faecalis, pneumococci, staphylococcus aureus, staph. albus and staph. citreus, neisseria spp, n. meningitidis, corynebacteria, aerobic lactobacilli, b. subtilis, h. influenzae, coliform organisms, and candida spp. many of the known potentially pathogenic members were present in lar ...19714399776
kinetic studies of the reaction mechanism of dihydrofolate reductase. 19714399848
antifolate resistance and the genetic control of dihydrofolate reductase activity. 19714399850
platelet interaction with bacteria. i. reaction phases and effects of inhibitors.interactions between human platelets and several common species of bacteria have been studied in vitro by the technic of recording nephelometry. results of this investigation have established the following parameters of platelet-bacterial interaction: (1) bacteria are potent stimuli of the platelet-aggregating reaction. (2) the platelet-bacterial interaction proceeds through four distinct phases which are separable by varying the platelet-bacterial ratios or adding appropriate chemical inhibitor ...19714400052
dihydrofolate reductases: structural and mechanistic aspects. 19714400072
bacterial resistance to penicillins and cephalosporins. 19714401418
[tetrazolium bioautography of pteroylglutamic acid conjugates]. 19714401878
mechanisms of azo reduction by streptococcus faecalis. i. optimization of assay conditions. 19714403481
effects of essential amino acid starvation in streptococcus faecalis: structural change in the 50s ribosomal subunit.the 50s ribosomal subunits obtained from exponential-phase and valine-limited cultures of streptococcus faecalis 9790 differed in protein content. approximately 35% of the valine-limited subunits showed protein losses when analyzed by cscl density centrifugation after formaldehyde fixation. results of density gradient analysis and of acrylamide gel electrophoresis localized the protein to a "split" subunit fraction. no differences could be detected in the protein contents of 30s subunits from ex ...19714925120
pressure sensitivity of streptococcal growth in relation to catabolism.the sensitivity of streptococcus faecalis growth to hydrostatic pressures ranging up to 550 atm was found to depend on the source of adenosine triphosphate for growth. barotolerance of cultures growing in a complex medium with ribose as major catabolite appeared to be determined primarily by the pressure sensitivity of ribose-degrading enzymes. apparent activation volumes for growth were nearly identical to those for lactate production from ribose, and yield coefficients per mole of ribose degra ...19714925191
[l forms of bacteria. i. cultural characteristics of l forms of staphylococcus aureus and streptococcus liquefaciens]. 19714949184
[l forms of bacteria. ii. quantitative aspects of the induction on agar of staphylococcus aureus and streptococcus liquefaciens in l phase]. 19714949185
levels of dihydrofolate reductase and thymidylate synthetase in strains of streptococcus faecium resistant to substituted pyrimidines, triazines and mtx. 19715002296
empirical vs. rational approaches in cancer chemotherapy. 19715002298
deaza aalogues of amethopterin (methotrexate). 19715002299
synthesis and biological activity of tricyclic antifolate compounds with fixed geometry. 19715002300
bacteriological evaluation of two test methods for chlorine in swimming pools.it was found that orthotolidine and plastic test strips containing a mixture of syringaldazine and vanillinazine gave different results as to chlorine content of water samples containing urine or large amounts of bacteria while giving consistently similar results with water samples having only sodium hypochlorite added. orthotolidine was found to give erroneously "safe" readings when in fact viable bacteria were observed on membrane filters after filtration.19715002311
heat survivor curves of food-borne bacteria suspended in commercially sterilized whole milk. ii. bacteria other then salmonellae. 19715002381
action of diastereoisomers of tetrahydrohomofolate on the growth of lactobacillus casei. 19715002438
new approaches to chemotherapy. 19715002440
catabolism of l-arginine by entrapped cells of streptococcus faecalis atcc8043. 19715002471
[preliminary studies of apo-tyrosine decarboxylase inhibitors]. 19715002561
platelet interaction with bacteria. ii. fate of the bacteria.several common strains of bacteria have been studied to determine their influence on human and rabbit platelets in vitro. bacteria at a nominal ratio of 1:1 were added to platelets in their native plasma or to platelets in a balanced salt solution. the platelet-bacterial interaction was examined by nephelometry and by sequential light microscopy of fixed specimens taken at key points in the reaction. the results support the following conclusions: (1) bacteria that were potent stimuli of the plat ...19715002629
the role of folate coenzymes in the initiation of protein synthesis. 19715002669
intestinal bacteria and the hydrolysis of glycosidic bonds. 19715002686
bacteriological assessment of clindamycin, a new lincomycin derivative. 19715002688
[enterocin formation and typing of streptococcus faecalis]. 19715002787
a study of specificity of cores fro group d streptococci. 19715002808
specific detection of antigen-binding cells by localized growth of bacteria.a new method for the enumeration of lymphoid cells with specific surface-receptors for antigen is described, based on the use of beta-d-galactosidase (ec 3.2.1.23), either directly as an antigen or as a conjugated antigen. binding of beta-d-galactosidase is revealed by its activity in releasing riboflavin from a synthetic substrate, riboflavin-beta-d-galactopyranoside. the riboflavin, inactive as a vitamin in the galactosidic form, becomes active when released by the enzyme, and can be detected ...19715002817
the "sensitivity" of resting and dividing cells. 19715002845
asymptomatic bacteriuria in pregnancy in assiut, upper egypt. i. report on the first one thousand cases investigated. 19715002926
changes induced in the ultrastructure of the cytoplasmic and intracytoplasmic membranes of several gram-positive bacteria by variations in oso 4 fixation. 19715003136
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