Publications

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shigellosis among the chinese veterans: ii. 10-year clinical and laboratory review. 19744607958
letter: shigella enteritis venereally transmitted. 19744608062
reduction in oxygen enhancement ratio with increase in let: tests of two hypotheses. 19744609938
the effects of experimental uveitis on anterior uveal prostaglandin transport and aqueous humor composition. 19744609946
effect of calcium on the cell infectivity of virulent shigella flexneri 2a. 19744610242
an ontogenic study of the acute inflammatory reaction in the fetal rhesus monkey. i. cellular response to bacterial and nonbacterial irritants. 19744610278
[transmissible drug resistance in enterobacteria]. 19744610983
imported diseases in general practice. gastrointestinal disorders. 19744611581
[role of biocenosis in the manifestation of shigella virulence]. 19744613073
[sensitivity of the causative agents of dysentery to certain antibiotics according to data from 1958-1972]. 19744613074
[clinical aspects and diagnosis of diarrhea of a conditionally pathogenic etiology]. 19744613077
[modern concepts of immunity in bacterial dysentery (a review)]. 19744613079
immunogenic value of live, inactivated and cell-free dysentery vaccines. 19744613127
live oral shigella vaccine: vaccination schedule and the effect of booster dose. 19744613128
use of a new phage preparation in prophylaxis and treatment of shigellosis. 19744613130
a sensitive and rapid method for antibody determination by gel adsorption. 19744613136
substitution of virulent shigella and escherichia coli variants by avirulent germs in mixed culture. 19744613137
immunity against dysentery after enteral immunization with live vaccine. 19744613140
oral immunization against dysentery. 19744613142
[prevention of dysentery infections in human collectivities by means of polyvalent bacteriophages s. flexneri and s. sonnei]. 19744614332
[mass bacterial diarrhea epidemic aboard a fishing vessel anchored in a western africal port (lagos, nigeria)]. 19744614389
[elimination of the transmissible resistance to drugs in some enterobacteria in vitro]. 19744614551
biological properties of lipid a from shigella sonnei. 19744614974
[clinical aspects and etiotropic therapy of acute bacillary dysentery in infants and young children]. 19744615292
[case of mass dysentery infection of food origin]. 19744615510
the chemical basis of the shigella flexneri-o-antigens. 19744616052
[viability and retention of virulent properties by shigellae lyophilized in different protective media]. 19744616566
[reasons behind a scheme for identifying shigellae]. 19744616569
[a study of the location of different o-antigen components on the surface of sh. flexneri cells by the ferritin method]. 19744616570
[the stability of drug resistance in vivo]. 19744616583
[clinico-epidemiologic significance of episomal resistance to antibiotics in shigellae]. 19744616591
[organ culture of the human embryonic intestine as a model for the study of the interaction of dysentery bacteria with cells]. 19744617571
kinetics of thermal death and prediction of the stabilities of freeze-dried streptomycin-dependent live shigella vaccines. 19744617756
an attempt at the identification of phage receptors in shigella flexneri. 19744618423
in vitro susceptibility of shigella strains to trimethoprim and sulfamethoxazole.trimethoprim and sulfamethoxazole were tested alone and in combination against 227 recently isolated shigella strains. variations in medium constituents and inoculum size were used to determine the optimal testing conditions. the plate dilution method with addition of 5% lysed horse blood to the susceptibility test medium and an inoculum size of 10(2) organisms was found to provide satisfactory results. all 227 strains were inhibited by low concentrations of trimethoprim, and all were susceptibl ...19744618458
reversal- and non-reversal-shift discrimination learning as a function of drive in albino rats. 19744820502
protein digestion in the intestine of sheep. 19744820968
some comparative effects of racemic methadone and its optical isomers in rodents. 19744828761
variations in hematologic responses to increased lead absorption in young children.in the study of human populations, much emphasis is placed on the concentration of lead in whole peripheral blood. there is a considerable body of evidence which indicates that this measurement reflects recent and current assimilation of lead. while broad ranges in blood lead concentration have been associated with differing risks of toxicity for groups, it is not a precise index of adverse effect per se, even at elevated levels. within the red blood cell itself there is not a close association ...19744831151
effects of vitamin e-deficiency on guinea pig lysosomes. 19744834468
a contribution to biology of grawitz's kidney tumor: heterotransplanatation. 19744835486
lymphocytopenia in acute experimental renal failure. 19744846717
[effects of tritiated water on the fetal hematopoietic development in rats]. 19744848619
the dynamics of the allomorphic forms of mouse mitochondrial dna. 19744854733
the effect of age on human third molar and rat molar teeth. 19744854738
purification and characterization of the molybdenum-iron protein component of nitrogenase from soybean nodule bacteroids. 19744855615
effect of triiodothyronine on thyroliberin-induced somatotropin release in patients with acromegaly. 1974414908
[the life and work of assistant professor václav skalák]. 1974380150
acceptance of hospital-related group practices vary widely. 1974428966
new antimicrobial nitrofuran, trans-5-amino-3-[2-(5-nitro-2-furyl)vinyl]-delta2-1,2,4-oxadiazole: antimicrobial efficacy in mice, rats, and guinea pigs.a new antimicrobial nitrofuran designated sq 18,506 showed some therapeutic activity when administered orally to mice infected with escherichia coli, salmonella schottmuelleri, shigella flexneri, or klebsiella pneumoniae. animals infected parenterally with streptococcus pyogenes, proteus mirabilis, mycobacterium tuberculosis, and candida albicans, or topically with trichophyton mentagrophytes, did not respond to therapy with the drug at the dosage levels used. the compound was as effective as me ...197415830472
what's primary in primary nursing? 1975415203
[in vitro radioimmunological research]. 1975415209
the cathode bound group antigen of dysentery-provoking escherichieae (author's transl).antigens from disrupted cells of dysentery-provoking and of non-enteropathogenic escherichieae were submitted to immunoelectrophoresis on cellulose acetate stripes at ph 8.0. among 6 immune sera produced for this purpose by immunizing rabbits against desintegrated dysentery bacteria, only one contained a precipitine reacting with an antigen similar to the "generic antigen" of belaya. this - at ph 8.0 - cathode-bound group antigen (kga) could not only be found in virulent but also in 5 attenuated ...1975873
use of lincomycin, methicillin and ristomycin in the nutrient media for isolating pathogenic intestinal microorganisms.elective-differentiating solid nutrient media for simultaneous isolation of vibrioes, salmonella and shigella were developed. antibiotics active against grampostive microflora and dry bile salts inhibiting the growth of proteus were used as the inhibitors of the growth of the accompanying microflora. the medium was lincomycin and the bile salts may be prepared in a dry form.19752096
lactulose therapy in shigella carrier state and acute dysentery.antibiotic-resistant shigella are increasingly prevalent. lactulose, a non-absorbable disaccharide, was investigated as an alternative therapy for shigella infection on the hypothesis that the short-chain fatty acids (inhibitory to shigella) resulting from metabolism of lactulose by normal colonic flora would diminish shigella excretion. a long-term antibiotic-refractory carrier (large bowel) excreting 10(4) to 10(7)shigella sonnei/g of feces was given two courses of lactulose (of 24 and 16 days ...19752098
testicular androgen binding protein (abp) - a parameter of sertoli cell secretory function.using abp as an index of sertoli cell secretory function, several important features of the sertoli cell have emerged: 1. the stimulation of abp production by fsh clearly points to the sertoli cell as a target cell for fsh (3,4,9-16,21,24). 2. the dramatic effects of androgens on abp production both in immature and mature rats also suggest that the sertoli cell is a target cell for androgen (3,12,14,16,25). 3. the striking reduction in abp production in the cryptorchid testis raises the question ...197518322
[proceedings: new method for chronic implantation of cortical electrodes]. 197554071
[study of the ability of shigella sonnei and flexneri to inactivate antibiotics]. 197554495
[study of the role of type-specific antigen in the process of shigella flexneri interaction with epithelial cell and macrophage cultures].epithelial cells of the hep-2 line infected in parallel by genetically connected strains of sh. flexneri, differing in the capacity to synthesize the type antigen were studied morphologically. the type antigen proved to show no significant influence on the penetration of dysentery bacilli into the cell. a study of the process of phagocytosis of the mentioned strains by a culture of peritoneal macrophages of guinea pig demonstrated that the presence of a type antigen communicated to the bacteria ...197555022
[obtaining purified preparations of individual shigella newcastle k- and o-antigens by using an ultracentrifugation method].a modified method of obtaining the purified k- and o-antigens of sh. newcastle with the use of ultracentrifugation is described. serologically individual k- and o-antigens were obtained and their chemical composition was studied. polysaccharide of the k-antigen consisted of the galacturonic acid, galactose, glucose, rhamnose xylose and hexosamine; it contained no heptoses. the o-antigen contained galactose, glucose, mannose, rhamnose, heptose and hexosamine; in difference to k-antigen was equal ...197555023
[localization on the shigella flexneri f6s chromosome of a rfa gene implicated in the biosynthesis of bacterial cell wall lipopolysaccharide]. 197558625
[receptor sites for phages specific for r mutants of shigella flexneri]. 197558628
[the metabolism of 4-14c-pregnenolone in tissue sections of human ovaries and their modification by chlormadinone acetate].in vitro incubations with slices of two normal human ovaries and 4-14c-pregnenolone as precursor were carried out to study the possibility of a direct influence of chlormadinone acetate on the metabolism of pregnenolone. in agreement with our previous studies the incubations of the ovary from the follicle phase of the cycle yields a profile of steroids different from that of the ovary from the corpus luteum phase of the cycle. under the experimental condition chosen, the presence of enzymes of ...197558782
dynamic determinants of letf ventricular diastolic pressure-volume relations in man.left ventricular (lv) diastolic pressure (p), volume (v), and rate of change of volume (dv/dt) were determined at 16.7 msec intervals in 17 patients (simultaneous micromanometer and single plane volume angiography). four patients had mitral stenosis with atrial fibrillation and 13 patients (three normal, two congestive cardiomyophathy, three lv hypertrophy, and five coronary artery disease) were in normal sinus rhythm. maximum early diastolic filling rates (max dv/dt) in the normal and cardiomyo ...1975122921
[endemic dysentery in psychiatric institutions, exemplified by the land hospital, schleswig, for child-and adolescent-psychiatry (author's transl)]. 1975123321
[effects of caudate nucleus stimulations on the primary and secondary endings activity of soleus muscle spindle].effects of repetitive stimulation of the contralateral caudate nucleus on the static discharge and dynamic sensitivity of soleus muscle spindle primary and secondary endings were studied in cats anaesthetized with halothane (fluothane). by progressive increasing the depth of anaesthesia two different fusimotor effects could be observed. 1. a static facilitatory effect; under light anaesthesia the static discharge of primary and secondary endings were strongly increased. the response of the prima ...1975123860
intramyocardial pressure: effect of preload on transmural distribution of systolic coronary blood flow.impairment of systolic coronary blood flow (cbf) may be mediated by intramyocardial pressure (pim). however, the effect of systole on the magnitude and transmural distribution of coronary blood flow has not been investigated. the purpose of this study was to measure this effect, and, indirectly, intramyocardial pressure. it is assumed that intramyocardial pressure acts on the coronary vessels as a starling resistor, such that local coronary blood flow is determined by the equation: coronary perf ...1975124128
hepatic mitochondrial function in ketogenic states. diabetes, starvation, and after growth hormone administration.the study was designed to evaluate hepatic mitochondrial function during ketotic states. the ketogenic models studied were streptozotocin-induced diabetic ketoacidosis, 48 h of starvation, and after growth hormone administration. in the last-mentioned model we observed increased free fatty acids but not ketonemia. oxidative phosphorylation was measured using the citric acid cycle substrates pyruvate and succinate, the amino acid glutamate, a ketone body beta-hydroxybutyrate, and a long-chain fat ...1975124319
effects of n-ethylmaleimide on the atpase activities of cardiac myosin from thyrotoxic rabbits. 1975124376
[possible causes determining the developmental rhythm of populations of the nasopharyngeal gadfly of sheep, oestrus ovis l. (diptera, oestridae)].on the basis of observations undertaken in azerbaijan and available literary data the author considers the hypotheses concerning the reasons causing the delay of the ist instar larvae development and determining the age structure changes in population of oestrus ovis l. within a year. the main reasons are as follows: factors depending on the population density at the larval phase, the light day duration within the life cycle of the botfly females.1975124845
stimulation of syngeneic and allogeneic lymphoid cells by tumour cells in vitro.august and wistar rat lymph node cells were found to respond well to pha stimulation and in mixed lymphocyte culture, as determined by an increased incorporation of 3h-thymidine. august rat lymph node cells were also stimulated by incubation with irradiated syngeneic tumour cells. allogeneic wistar rat lymph node cells produced a larger response to the august tumour cells. the response of syngeneic and allogeneic lymph node cells was reduced by pretreating the tumour cells with a wistar anti-tum ...1975126072
cytochemical identification of atpase-positive langerhans cells in edta-separated sheets of mouse epidermis.sheets of epidermis for incubation to demonstrate atpase activity were obtained from specimens of mouse footpad using edta as the separation medium. the use of edta in place of the nabr method previously described, resulted in a greatly reduced incubation time, precise localization of reaction product and preservation of ultrastructural detail. a population of closely and regularly spaced atpase-positive dendritic cells was demonstrated by light microscopy. electron microscopy demonstrated that, ...1975126073
[clinical conference: histamine and basophils after cellular separation on albumin gradient]. 1975126441
interactions of the third component of complement (c3) with cross-linked dextran. iii. isolation and characterization of interacting components after enzymatic digestion of complement coated cross-linked dextran.in previous investigations we could show that incubation of cross-linked dextran (sephadex) with normal human and normal guinea pig serum results in the binding of c3 to sephadex. this binding was found to be due to activation of c3 via an alternate pathway. in this paper data are presented which show that components bound to sephadex can be recovered after enzymatic digestion of serum-reacted sephadex beads. the digests were characterized with immuno-electrophoresis and double immunodiffusion t ...1975126570
effect of methysergide, a blocker of serotonin receptors, on plasma prolactin levels in lactating and ovariectomized rats.the effect of methysergide (mes, 2.5 mg/100 g body wt), a serotonin antagonist, on prolactin release has been studied in lactating and ovariectomized rats. mes caused significant increases in prolactin release in both animals. studies in ovariectomized, hypophysectomized rats indicate that this effect is not due to a decrease in the peripheral metabolism of prolactin. in vitro incubations of anterior pituitary fragments with mes failed to demonstrate any increase in prolactin release, suggesting ...1975126860
characterization of 5.8s ribosomal ribonucleic acid in neurospora crassa.neurospora crassa ribosomes contain a species of ribonucleic acid (rna) of molecular weight 54,000, similar to 5.8s ribosomal rna previously described for other eukaryotic organisms. the 5.8s rna from n. crassa was found to be released by heat treatment at 60 c from 25s ribosomal rna but not from 18s ribosomal rna. the base composition of n. crassa 5.8s rna was similar to that of 5.8s rna from saccharomyces cerevisiae, but differed from animal 5.8s rna. during the course of this study, it was di ...1975126993
purification and properties of membrane-bound coupling factor-latent atpase from mycobacterium phlei.the membrane bound coupling factor-latent atpase was solubilized from the membrane vesicles of mycobacterium phlei by using 0.25 m sucrose or low ionic strength buffer. purification of the solubilized enzyme by use of sepharose-adp conjugate gel yielded a homogenous preparation of latent atpase which was purified about 216-fold in a single step with an 84% yield. the enzyme exhibits a specific activity of 39 mumoles of atp hydrolyzed per min per mg protein. the purified enzyme exhibits coupling ...1975127086
the significance of coronary arterial stenosis during cardiopulmonary bypass.myocardial infarction may develop during an uneventful open-heart operation. in order to better understand this complication, we undertook an experimental study. the left circumflex coronary artery of 20 dogs was narrowed to 50 per cent of its area by a metal screw clamp to produce a localized coronary stenosis. regional myocardial perfusion in the distribution of both the stenotic circumflex and normal left anterior descending (lad) coronary arteries was measured by injection of a radioactive-l ...1975127092
the hurler syndrome: treatment of cultured hurler fibroblasts with normal human serum.prolonged replacement of fetal calf serum by normal human serum for the enrichment of medium during tissue culture of hurler fibroblasts resulted in increased acid mucopolysaccharides in the cells and in the medium. the predominant intracellular mucopolysaccharide had the characteristics of dermatan sulfate when hurler cells were treated with either serum. normal human serum contains a nonspecific coreective factor capable of augmenting the loss of 35so4-amps from hurler cells, but not from norm ...1975127180
direct and utilization of metabolic energy for transport processes within proximal convolution. 1975127689
immunologic relationship among fibrinolysins secreted by cultured mammalian tumor cells. 1975127717
prevention of thrombosis after small artery endarterectomy, with dextran and fibrinolytic agents. 1975127798
human muscle spindles: fine structure of the primary sensory ending.the primary sensory innervation of muscle spindles obtained by muscle biopsy of normal human volunteers was studied with the light and electron microscopes. the parent ia sensory fibre branched 4-6 times, became unmyelinated for 25-30 mum, then formed sensory terminals on each nuclear bag and chain intrafusal muscle fibre. the first 4--5 mum of the unmyelinated segment is believed to be an encoder zone because the plasmalemma was undercoated by a dense granular layer similar to that under other ...1975127831
observations on epizootiology and distribution of elaeophora schneideri in montana ruminants.seventy-four moose, 111 elk, 20 mule deer, 8 white-tailed deer, 26 prong-horn antelope, 42 domestic sheep and 3 bighorn sheep from montana or northwestern wyoming were examined post-mortem for evidence of elaeophora schneideri infection in 1973-74. fifteen percent of the mule deer and four percent of the moose were positive for adult arterial worms. this constitutes the first report of e. schneideri in mule deer in montana. no gross signs of blindness or other neurologic disorder were evident in ...1975127848
microautoradiographic study of cell proliferation in compensatory renal growth.dna synthesis in the renal parenchyma was studied by electron microscopic autoradiography 48 and 72 hours after unilateral nephrectomy in mice and weanling rats. the proportion of labelled nuclei belonging to the epithelium, endothelium, interstitial areas, or circulating cells was evaluated. most of cells showing dna synthesis were epithelial but many belonged to stroma. all the nephron segments were found to participate in compensatory hyperplasia, with a greater contribution, however, of the ...1975127941
identification and actions of gastric inhibitory polypeptide. 1975128084
physiopathological aspect of glynn's type of experimental arthritis.knee joint arthritis is induced among rabbits previously immunized by intradermal injection with egg albumin (ea) emulsified in adjuvant containing either m. tuberculosis or m. butyricum, then by intra-articular injection with ea. arthritis evolution involves two phases, an early one during the first 2 months and a late one from 3 months to 1 year. during the early phase, arthritis intensities are similar no matter which mycobacterium is used. however, during the late phase, only rabbits immuniz ...1975128112
[solubility of the mg2+-dependant ca2+-activated atpase fraction of the plasma membranes of synaptosomes].mg2+-dependent ca2+-activated atpase (mg2+,ca2+-atpase, ec 3.61.4) in the fraction of synaptosome plasmatic membranes is activated with 0.05-0.08% solutions of digitonin and sodium deoxycholate. at higher concentrations of digitonin the activating effect lowers, sodium deoxycholate in the increasing concentrations inactivates the enzyme. 0.08% digitonin activates mg2+,ca2+-atpase of synaptosome membranes, without demanding for its transition into solubilized state. separation of non-active 0.08% ...1975128171
[enzymatic properties in muscle membranes].a study in the enzymatic properties of muscle membranes established that sarcolemma of the rabbit skeletal muscles contains the ca2+-atpase system which does not require mg2+ for manifestation of ions activity. by some kinetic properties it differs from atpase of myosin. the complex ca-atp2+ is a substrate of ca2+-atpase. ions of a series of bivalent metals inhibit the latter as well as the passive transport of ca2+, that may evidence for a definite relation of ca2+-atpase with ca+2 transport in ...1975128174
[changes in the lungs and the mass of the right ventricle of the heart in chronic hypoxia (experimental-morphological study)].in experiments on 105 white rats using histological, histochemical, and morphometric methods the state of the lungs following daily "rises" in a pressure chamber to the "hight" of 5000--9000 m at verious time intervals--from 1 day to 9 weeks was studied. in 18 animals "ascents" were preceded by sinistral pulmonectomy. in parallel, the heart was investigated by the method of separate weighing. at initial stages changes in the lungs were characterized predominantly by impairment of the blood- and ...1975128341
the effect of butacaine on adenine nucleotide binding and translocation in rat liver mitochondria.the effect of the local anaesthetic, butacaine, on adenine nucleotide binding and translocation in rat liver mitochondria partially depleted of their adenine nucleotide content was investigated. the range of butacaine concentrations that inhibit adenine nucleotide translocation and the extent of the inhibition are similar to the values obtained for native mitochondria. butacaine does not alter either the total number of atractyloside-sensitive binding sites of depleted mitochondria, or the affin ...1975128352
[classification of white, coagulase-negative staphalococci by means of lysotyping]. 1975129044
[an outbreak of dysentery caused by sh. flexneri var. x]. 1975130767
inactivation of viruses and bacteria by ozone, with and without sonication.selected organisms with public health significance were placed in a reaction chamber for treatment by ozonation, by ozonation and sonication, by sonication, or by sonication during oxygenation. vesicular stomatitis virus, encephalomyocarditis virus, gdvii virus, staphylococcus aureus, pseudomonas fluorescens, salmonella typhimurium, enteropathogenic escherichia coli, vibrio cholerae, and shigella flexneri were inactivated by treatment with ozone. when microorganisms were suspended in phosphate-b ...1975163616
prevention of gram-negative bacillary pneumonia using polymyxin aerosol as prophylaxis. ii. effect on the incidence of pneumonia in seriously ill patients.all 744 patients admitted to a respiratory-surgical intensive care unit (rsicu) were included in a prospective study of the effects of a polymyxin (2.5 mg/kg body wt/day in six divided doses) or a placebo aerosol sprayed into the posterior pharynx and tracheal tube (if present), during 11 alternating 2-mo treatment cycles. the incidence of upper airway colonization in the rsicu with pseudomonas aeruginosa was 1.6% during the polymyxin treatment cycles (total 374 patients) and 9.7% during the pla ...1975163848
pathophysiology of acupuncture: nervous system transmission.as far as we know, this is the first scientific report which shows distinctly that acupuncture is transmitted directly by the nervous system and the performance of analgesic acupuncture requires an intact nervous system. the more distal the acupuncture treatment is given upon the nerve, the greater the degree of analgesia is afforded. the slowing from a normal awake beta to a normal awake alpha electroencephalographic rhythm may have some effect on the patient's pain perception but further inves ...1975164810
oncogenic transformation of murine lymphoid cells by in vitro infection with abelson leukemia virus.spleen cell cultures stimulated to dna synthesis by antigen or mitogen were infected with abelson virus, a c-type rna virus inducing nonthymic lymphomas in mice. after 3 days the cells were transferred to mice and caused 100 percent incidence of lymphomas in as few as 29 days. that a number of the tumors were of donor origin, as shown by female karyotypes in recipient male mice, indicated that cells infected by virus in vitro were transformed. the process depended upon both virus and stimulation ...1975165315
angel rotor countercurrent chromatography. 1975165750
thymosin-induced differentiation of murine thymocytes in allogeneic mixed lymphocyte cultures.calf thymosin is shown to enhance the one-way mlr of cba thymocytes cultured with allogeneic mitomycin-c- treated c57bl/j6 spleen cells. thymosin does not enhance the one-way mlr of cba thymocytes cultured with syngeneic mitomucin-c-treated spleen cells. based on this finding we present a relatively simple, rapid and quantitative in vitro microculture hioassay for inducers of t-cell differentiation and propose that thymosin treatment, when accompanied by antigen presentation, induces the two-ste ...1975165764
revertants of escherichia coli mutants defective in the cyclic amp system. 1975165780
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