Publications

somatic antigens of shigella. structural investigation on the o-specific polysaccharide chain of shigella dysenteriae type-2 lipopolysaccharide.	the o-specific polysaccharide obtained from shigella dysenteriae type-2 lipopolysaccharide by mild acid hydrolysis consisted of n-acetylgalactosamine, n-acetylglucosamine, d-galactose, d-glucose, and o-acetyl group in the ratio of 2:1:1:1:1. a number of oligosaccharides were obtained by deamination of the n-deacetylated polysaccharide and by smith degradation of the both native and o-deacetylated polysaccharides. the identification of oligosaccharides along with methylation analysis and chromic ...	1977	330162
[shigella shige as an etiological factor of bacillary dysentery].		1977	330362
shigellosis control--a rosy future?		1977	333037
shigella surveillance in the united states, 1975.		1977	333038
algorithms in the diagnosis and management of exotic diseases. xxvii. shigellosis.		1977	333040
some effects of intravenous prostaglandin e, and endotoxin in young chickens.	1 the effects of intravenous prostaglandin e1 and endotoxin were studied in young chickens (11-17 days old). 2 at a thermoneutral ambient temperature (31 degrees c), intravenous prostaglandin e1, produced behavioural and electrocortical sleep, increased oxygen consumption and, after an initial fall, elevated body temperature. below thermoneutrality (16 degrees c), the initial hypothermic effect was more marked and oxygen consumption was lowered. 3 the soporific actions of prostaglandin e1 were s ...	1977	334307
some effects of prostaglandins e1 and e2 and of endotoxin injected into the hypothalamus of young chicks: dissociation between endotoxin fever and the effects of prostaglandins.	prostaglandins e1 and e2 elevated body temperature of young chicks when injected into the hypothalamus at thermoneutrality (31 degrees c). in contrast, they lowered body temperature when so injected below thermoneutrality (16degreesc): the relation of the fall in body temperature to increased heat loss and decreased heat production was examined. 2 the above effects below thermoneutrality were potentiated by pretreatment with inhibitors of prostaglandin synthetase and possible reasons for this po ...	1977	334308
somatic antigens of shigella. the strucuture of the specific polysaccharide chain of shigella dysenteriae type 5 lipopolysaccharide.	the specific polysaccharide was released from shigella dysenteriae type 5 lipopolysaccharide by mild acidic hydrolysis and then purified by gel chromatography on sephadex g-50. the polysaccharide was built up of residues of d-mannose, 2-acetamido-2-deoxy-d-glucose, 3-0-(d-1-carboxyethyl)-l-rhamnose (rhamnolactylic acid) and 0-acetyl groups in a ratio 2:1:1:1. on the basis of radiospectroscopy, methylation analysis, smith degradation, and chromium trioxide oxidation, the repeating oligosaccharide ...	1977	334537
cell-wall lipopolysaccharide of the 'shigella-like' escherichia coli 058. structure of the polysaccharide chain.	two lipopolysaccharide preparations were obtained from escherichia coli 058 by extraction with 45% aqueous phenol and fractional precipitation with cetyltrimethyl ammonium bromide (cetavlon). chemical analysis and polyacrylamide gel electrophoresis in the presence of sodium dodecylsulfate showed that the two preparations differed only in the extent of the o-specific polysaccharide moiety. the o-specific polysaccharide was characterized with proton magnetic resonance and infrared spectroscopy, op ...	1977	334542
location of new clear plaque genes on the p1 map.		1977	335644
effects of methylxanthine drugs on pyrogen-induced hyperthermia.	the hyperthermic response to pyrogen was not potentiated by caffeine or theophylline administered i.p. into cats or rabbit. injection of these drugs into the anterior hypothalamus or into the third cerebral ventricle in cats was also without effect on pyrexia. these results support the hypothesis that cyclic amp in the anterior hypothalamus does not mediate pyrogen-induced hyperthermia in cats.	1977	336383
toxin from the culture filtrate of shigella dysenteriae that causes morphological changes in chinese hamster ovary cells and is distinct from the neurotoxin.	a toxin that causes morphological changes in chinese hamster ovary cells was isolated from a culture filtrate of shigella dysenteriae 1. it was partially purified by successive column chromatography on diethylaminoethyl-cellulose, bio-gel a-5m, and hydroxylapatite. the toxin was separated from neurotoxin by diethylaminoethyl-cellulose column chromatography and was not lethal for mice.	1977	336549
[characteristics of the ultrastructural changes of the large intestine mucosa after acute dysentery].	electron microscopic examinations of biopsy specimens of the large intestine from 8 patients one month after termination of the acute phase of dysentery revealed dystrophic and destructive changes in surface epithelium cells consisting in the lack of glycocalyx, fragmentation of microvilli, vacuolation and subsequent homogenization of the cytoplasm. swelling and destruction of mitochondria, pyknosis and rhexisof the nucleus, exposure and loss of the intactness of the apical membrane of the cells ...	1977	337939
rose spots in shigellosis caused by shigella dysenteriae type 1 infection.		1977	338095
an overview of recent experiences with plasmid-mediated antibiotic resistance or induced virulence in bacterial diseases.		1977	340443
[an epidemic of bacillary dysentery caused by shigella dysenteriae, type 1, in mogadiscio].	an epidemic of bacillary dysentery broke out at mogadiscio in the first months of 1976 produced by shigella dysenteriae type 1 supplanting all other familiers of shigella before present in the zone. the date are relative to 675 cases with 27 deceased. the hydrological origin of epidemy was not probable.	1977	341817
[study of the antigenic relationship between shigella and leptospira. i. antigenic relationship between shigella dysenteriae, type 1 and leptospira sejroe, leptospira hardjo and leptospira sao paulo].		1977	341818
synergy and rifampicin.		1977	405361
immunization with shigella dysenteriae type 1: evaluation of antitoxic immunity in prevention of experimental disease in rhesus monkeys (macaca mulatta).	the role of serum antitoxic antibody in protection against the dysentery caused by shigella dysenteriae type 1 (shiga's bacillus) was studied in monkeys fed 10(10) virulent organisms after parenteral immunization with a formalin-inactivated shiga toxoid preparation standardized in mice. two 125-microgram doses of toxoid adsorbed on aluminum hydroxide adjuvant and given 14 days apart provided mice with a 54-fold increase in resistance to parenteral toxin. in rhesus monkeys (macaca mulatta), the s ...	1977	409782
effect of some bacterial products on platelet electrophoretic mobility (pem).	bacterial lps, used in our experiments, are able to decrease pem at concentration of 100 microgram/ml after incubation with 1 x 10(7) platelets/ml for 30 min at 37 degrees c. such effect is statistically significant for bacteroides fragilis lps, s. enteritidis and s. typhi. e. coli lps 026:b6 w and e. coli 055:b5 w are not effective at all, s. minnesota (incomplete) lps 595 and 345 free of 0-polysaccharide and partially lacking core in their molecule did not influence pem, while s. minnesota lps ...	1977	410424
[cell penetration by dysentery bacilli (author's transl)].		1977	415159
measuring interhemispheric transfer time in man.		1977	210552
in vitro strength of the human periodontal ligament.	the tensile properties of the human periodontal ligament were studied by direct loading and compression experiments. it was found that the ligament behaved in an elastic manner up to an elastic limit after which rupture occurred. the values obtained for the tensile strength of the ligament are in general agreement with those of other workers for similar tissues.	1977	264865
surgical adjuvant therapy for potentially curable cancer: the rationale of adjuvant chemotherapy and anticoagulant therapy.		1977	273400
immunosuppression in man: suppression by macrophages can be mediated by interactions with regulatory t cells.		1977	302274
binding of 3h-dexamethasone and 3h-corticosterone to rat liver cytosol during postnatal period.	the binding of 3h-dexamethasone (3h-dx) and 3h-corticosterone (3h-b) to specific binding proteins of rat liver cytosol was compared during pre- and postnatal period. the binding of 3h-dx was almost twice as high as that of 3h-b during the whole postnatal period. the scatchard analysis showed a number of binding sites for 3h-dx to be 4.44 x 10(-13) mol mg-1 (kd 5.9 x 10(-9) mol 1(-1)) and for 3h-b to be 2.7 x 10(-13) mol mg-1 (kd 1.6 x 10(-8) mol 1(-1)). a negative relationship between the bindin ...	1978	305844
amino acid transport in thymic- and spleen-derived lymphocytes.	we have examined the transport of amino acids by the sodium-dependent "a" and "asc" system in thymic- and splenic-derived lymphocytes from the long-evans rat. lymphocytes derived from the thymus transport amino acids by both the "a" and "asc" systems, whereas lymphocytes from the spleen transport amino acids by the "asc" system only. thymic lymphocytes are capable of establishing a steady state distribution ratio of 7.9 for 2-aminoisobutyric acid, but splenic lymphocytes can attain only 3.5. the ...	1978	308950
synthesis and analgesic-antiinflammatory activity of some 4- and 5-substituted heteroarylsalicylic acids.	we have made a series of 4- and 5-aryl- and 4- and 5-heteroarylsalicylic acid derivatives with the objective of reducing gastric irritation and increasing potency. here we describe a series of 4- and 5-heterocyclic salicylic acids and their antiinflammatory-analgesic potencies measured in comparison to aspirin. an improvement of the therapeutic index over aspirin of 100 was achieved; however, the heterocyclic salicylic acids lacked antipyretic activity. some physicochemical parameters which may ...	1978	309948
selective antagonism by d-alpha-aminoadipate of amino acid and synaptic excitation of cat spinal neurons.		1978	210880
supersensitivity to the cyclic gmp response to glutamate during cerebellar maturation.		1978	211431
demonstration of enzootic bovine leucosis virus in britain.		1978	219581
[nomenclature of the bacteria of the genus shigella and their systematic position in the family of enterobacteriaceae].		1978	371309
single-dose tetracycline therapy for shigellosis in adults.	forty-two adults who had shigella isolated from stool (26 symptomatic, 16 asymptomatic) received a single oral dose of tetracycline hydrochloride (2.5 g). minimal inhibitory concentrations of the 42 isolates demonstrated that 41% were sensitive to tetracycline. sixteen of 18 patients with diarrhea who had tetracycline-resistant shigella and all eight patients with diarrhea who had tetracycline-sensitive shigella were clinical well and had shigella-negative stools 48 hours after therapy. fifteen ...	1978	342737
antipyretics and fever induced in adult fowls by prostaglandins e1, e2 and o somatic antigen.		1978	347328
haemolytic-uraemic syndrome complicating shigella dystentery in south indian children.	shigella dysentery caused 65% of all cases of acute renal failure (arf) seen in children treated at the christian medical college hospital, vellore, during the 33 months ending september 1977. in the 40 children with arf secondary to shigella dysentery, haematological findings suggested that they were suffering from the haemolytic-uraemic syndrome, and glomerular hypercellularity and fibrin deposition were present in all 12 patients whose renal histology could be studied. peritoneal dialysis was ...	1978	350345
cerebellar afferent projections from the vestibular nuclei in the cat: an experimental study with the method of retrograde axonal transport of horseradish peroxidase.	details of cerebellar afferent projections from the vestibular nuclei were investigated by the method of retrograde axonal transport of horseradish peroxidase (hrp) in the cat. the distribution of labeled cells in the vestibular nuclei following hrp injections in various parts of the cerebellum indicates that vestibular neurons in the medial and descending nuclei and cell groups f and x project bilaterally to the entire cerebellar vermis, the flocculus, the fastigal nucleus and the anterior and ...	1978	350598
altered membrane-associated functions in chronic lymphocytic leukemia cells.	peripheral blood lymphocytes consisting mainly of neoplastic b cells from patients with chronic lymphocytic leukemia (cll cells) showed a markedly reduced response to the human b-cell mitogens anti-beta2 microglobulin, sepharose-bound protein a and sepharose-bound anti-human immunoglobulin (anti f(ab')2) in all of nine patients studied. on the other hand, cll cells from three out of eight patients tested responded well to the calcium ionophore a23187. sepharose-bound protein a and anti-beta2 mic ...	1978	350779
[conditions and factors determining the etiological structure of dysentery and its changes. report 1. epidemiological theory of etiological selectivity of the main (primary) pathways of infection and their differences in various nosological forms of dysentery].	the authors present the elaborated and formed epidemiological theory ("conformity theory") according to which the etiological structure of dysentery is determined by the etiological selectivity of the main (primary) waves of transmission of the infection differing in various nosological forms of dysentery. in grigoriev-shiga dysentery the domestic way of the spread of infection plays the main role, in flexner and newcastle dysentery--the water way, and in sonne dysentery--the food way (particula ...	1978	352042
a new approach for a pyrogen test [proceedings].		1978	352465
effects of certain cations (fe, zn, mg, and ca) on bacterial endotoxins.	the natural occurrence of cations fe, zn, mg, and ca in the lipopolysaccharide (lps) of both the s and r forms of shigella dysenteriae 1 was studied. lps preparations were obtained either by phenol-water extraction (according to the method of westphal et al., z. naturforsch. 7b:148-155, 1952) or by extraction of cells with hypertonic sodium chloride-sodium citrate (according to the method of raynaud and digeon, c. r. acad. sci. (paris) 229:564-566, 1949), with subsequent chromatographic purifica ...	1978	357292
interventions in diarrheas of infants and young children.	to prevent diarrhea, efforts must be directed toward decreasing environmental contamination of enteropathogens, altering exposure of persons to naturally occurring agents, or to increasing host tolerance to prevalent enteropathogens. a vaccine is feasible in the control of certain enteric infections among high risk groups: typhoid fever and cholera, in areas of hyperendemicity or during an epidemic, shigellosis in institutionalized populations that are at risk to develop illness due to known pre ...	1978	359524
surface structures of escherichia coli that produce diarrhea by a variety of enteropathic mechanisms.	strains of escherichia coli, mostly of human origin, were obtained from several different investigators who had isolated them from patients with diarrhea from many different parts of the world. the mechanisms by which these e. coli were thought to have caused diarrhea included: (i) synthesis of labile, stable, or shigella dysenteriae-like enterotoxins; (ii) invasion of the intestinal mucosa; and (iii) unknown. each strain was carefully examined for pili or flagella to correlate the presence or a ...	1978	361579
naturally occurring promoter down mutation: nucleotide sequence of the trp promoter/operator/leader region of shigella dysenteriae 16.	the promoter/operator/leader region of the trp operon of shigella dysenteriae 16 has single base pair differences from the corresponding region of escherichia coli at positions -24 and -13. the difference at -13 was shown to be responsible for the 90% reduction in promoter function characteristic of the trp operon of s. dysenteriae. the base pair difference at position -13 also renders the operator partially constitutive. this allows the organism to maintain relatively high repressed levels of t ...	1978	364484
a comparative evaluation of media in the isolation of shigella dysenteriae type 1.		1978	365721
the distribution of the inherited hl 1 and r 67 antigens on rabbit serum high density lipoprotein (hdl) particles.	qualitative and quantitative analysis of the distribution of hl 1 antigen and r 67 antigen on high density lipoprotein (hdl) particles were conducted on six rabbit sera. the hl 1 antigen showed non-identity with a-i-containing hdl particles, and antiserum to hl 1 did not remove a-i-containing hdl particles. the r 67 antigen showed partial identity with a-i-containing hdl particles. antiserum to r 67 antigen removed 30--40% of a-i-containing hdl particles from the sera of animals which were heter ...	1978	205613
tumorigenic action of streptozotocin on the pancreas and kidney in male wistar rats.	pancreatic islet cell tumors were induced in 38 of 44 male wistar rats (86%), which survived 9 to 14 months following the various treatment schedules. a single i.v. injection of streptozotocin alone, 30, 40, 50, or 65 mg/kg of body weight produced adenomas of pancreatic islet cells in 8 of 9 (89%), 6 of 7 (86%), 2 of 4 (50%), and 1 of 2 rats (50%), respectively. the neoplasms were seen in all of the 8 rats given a single i.p. injection of picolinamide, 250 mg/kg of body weight, 15 min before a s ...	1978	207424
synthesis and secretion of transferrin by cultured mouse hepatoma cells.	the mouse hepatoma cell (hepa-1) in tissue culture has been shown to synthesize and secrete three electrophoretically distinct transferrins. each of these forms of transferrin has a molecular weight of 77,000, as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. the concentration of each form is indicated by its staining intensity, which is highest in the form with the fastest mobility and lowest in the form with the slowest mobility. the relative rate of transferrin synth ...	1978	207612
acquisition and discrimination of appetitively and aversively conditioned heart rate responses in rhesus monkeys.	this report describes the acquisition of a conditional heart rate response to both classical aversive and appetitive conditioning in eight rhesus monkeys (macaca mulatta). the behavioral paradigm consisted of two discrete one minute tones followed by the corresponding unconditional stimuli, i.e., electric shock or purina monkey chow. a third tone followed by neither food nor shock served as a discriminative stimulus (ds). the conditional heart rate responses developed in two phases. the first ph ...	1978	108656
purification and properties of heme oxygenase from pig spleen microsomes.		1978	96115
naturally occurring diatomaceous pneumoconiosis in sub-human primates.		1978	96157
intrathecal gentamicin for refractory gram-positive meningitis.	the mortality for meningitis due to staphylococcus aureus or listeria monocytogenes remains high, ranging from 32% to 77%. we treated a patient with staphylococcal meningitis refractory to methicillin sodium and oxacillin sodium, and a patient with listeria meningitis refractory to penicillin g potassium and ampicillin sodium; both patients were cured when intrathecal gentamicin sulfate was added to the regimen. the combination of intrathecal gentamicin and a penicillin may be beneficial in refr ...	1978	96281
[the appearance of penicillin resistant gonococci. clinical, genetic and epidemiologic problems].		1978	96408
brain and liver aldehyde dehydrogenase activity and voluntary ethanol consumption by rats: relations to strain, sex, and age.	voluntary ethanol consumption and brain and liver aldehyde dehydrogenase (aldh) activity were measured in male and female rats of the tryon maze-bright (s1), tryon maze-dull (s3), and wistar strains. the levels of brain aldh measured in the different groups, corresponded well to the levels of ethanol consumption, while differences in liver aldh corresponded well to only the strain differences in ethanol intake. within individual groups, levels of ethanol consumption correlated better with levels ...	1978	96475
response of a rat rhabdomyosarcoma to neon- and helium-ion irradiation.		1978	96481
phospholipid content and activity of pure uridine diphosphate-glucuronyltransferase from rat liver.	rat liver phospholipids were radioactively labeled in vivo before purification of udp-glucuronyltransferase to homogeneity. the pure enzyme contained very little phospholipid (approx. 0.7 mol of phospholipid/mol of protein). the solubilization detergent lubrol 12a9 appeared to act as a phospholipid substitute, capable of supporting udp-glucuronyltransferase activity. phospholipase c did not inhibit the pure enzyme activity and pure udp-glucuronyltransferase was stimulated by 40--100% by the addi ...	1978	96816
genetic aspects of immunologic abnormalities in new zealand mouse strains.		1978	96842
behaviour of solute and particle markers in the stomach of sheep given a concentrate diet.	1. fistulated sheep given a concentrate diet were used to study the behaviour of solute ([51cr]edta) and particle ([103ru]phenanthroline) markers in the stomach under conditions of continuous feeding. 2. an injection of a mixed dose of [51cr]edta and [103ru]phenanthroline was given into the rumen and the time course of marker concentrations in the rumen and the abomasum was recorded. the curves were analysed on the assumption that the stomach of the sheep could be represented as two mixing compa ...	1978	96850
bovine transferrin glycopeptide: the relevance of its structure to interaction with the mammalian hepatic lectin that binds asialoglycoproteins.		1978	96919
test for differentiation of m. tuberculosis and m. bovis from other mycobacteria.	a test is described for selective inhibition of mycobacterium tuberculosis and m. bovis isolates in fluid medium. the method employs rho-nitro-alpha-acetyl-amino-beta-hydroxy-propiophenone (nap) as an inhibitory agent for differentiation of mammalian tuberculosis strains from other mycobacteria.	1978	96930
lipids of the streptomycettes. structural investigation and biological interrelation a review.	during a systematic investigation of lipids of streptomycetes a series of compounds of biochemical and microbiological interest have been isolated and characterized. these include several menaquinones, glycosyl diglycerides (glucuronosyl and isoladobinosym diglycerides), two ornithino lipids and a diol phospholipid. some of these lipids were not known previously as constituents of streptomycete cells although they have been encountered elsewhere; others have proved to be novel lipids. the result ...	1978	96946
[host-virus relationship during experimental spring viremia in carp].	one-summer-old virus-free carps produce both circulating interferon and neutralizing antibodies when stored at +20 degrees c and injected intraperitonealy with 10(5), 10(6), 10(7) p. f. u. of spring viremia of carp virus per fish: kinetics and intensity of interferon production are maximum for the highest virus imput (fig.) and neutralizing antibodies are present in most of the fish 2 1/2 months post infection (table).	1978	96984
[formation of cutaneous nerve trunks in the chick. ultrastructural and quantitative analysis].	in chick skin structuration of nervous trunks takes place at 14-15 days of incubation, at the time of formation of the adult pattern of cutaneous innervation. at this same stage, myelogenesis begins, but develops mainly after hatching: only 4% of axons are myelinated at hatching, 40% in 6-week old chickens and 60% in adults. this "critical" stage (14-15 days of incubation) apparently corresponds to the stabilization of cutaneous nerve supply.	1978	96985
[cutaneous respiration in a selachian (scyliorhinus caniculus l.)].	cutaneous oxygen consumption (mo2) and cutaneous oxygen uptake from the external medium were investigated in an elasmobranch scyliorhinus caniculus l. in spite of an important mo2 (2.75 +/- 0.28 nmol.mn-1 cm-2 ; n=6) a positive net flux of oxygen through the skin takes place (2.98 +/- 0.33 nmol. mn-1 .cm-2). the skin of the dogfish in an exchanger for oxygen supplying 10% of oxygen requirements of other organs of the body in these experimental conditions (t = 13 degrees c).	1978	97014
effect of pentagastrin on the rat small intestine after resection.		1978	97119
discrepancy between results of the streptozyme test and those of the antideoxyribonulcease b and antihyaluronidase tests.	comparison of the serum titers obtained with the streptozyme, the antistreptolysin o, the antideoxyribonuclease b, and the antistreptohyaluronidase tests suggested that the streptozyme test had failed to detect antibodies against streptococcal deoxyribonuclease b and hyaluronidase. moreover, sera that were negative in the streptozyme test could be shown by immunodiffusion to possess significant numbers of precipitins against extracellular factors produced by group a streptococci. follow-up studi ...	1978	97311
preliminary x-ray crystallographic data on phospholipase c from bacillus cereus.		1978	97390
effects of ethylenediaminetetraacetic acid-4 sodium solution on the surface of renal calculi and the uroepithelium.	tetrasodium ethylenediaminetetraacetic acid is one of the most effective agents that dissolve renal calculi, especially calculi containing calcium. to study the dissolving process of calculi in solutions, with or without trypsin, serial thin sections of renal calculi composed of calcium oxalate and/or phosphate were prepared and observed by polarizing microscopy. the effects of the solution on the surface of human renal calculi and rat uroepithelium also were studied by scanning electron microsc ...	1978	97399
[status of research on experimental atherogenesis].		1978	97489
biological influence of fat intake on mammary cancer and mammary tissue: experimental correlates.		1978	97651
the reinforcing property of ethanol in the rhesus monkey ii. some variables related to the maintenance of intravenous ethanol-reinforced responding.		1978	97716
[epidemic cerebrospinal meningitis and anti-meningococcic vaccination].		1978	97747
isolation care of infection-prone burn patients.	an experimental and clinical study of spread of colonisation between burn patients, and their susceptibility to infection, was performed. burn patients' polymorphonuclear neutrophil granulocytes (pmn) functioned poorly, particularly during the second week after injury which coincided with maximum growth of bacteria in the burn wound. patients with large burns often dispersed s. aureus and ps. aeruginosa but also beta-hemolytic streptococcus to the air of their rooms. airborne transfer of these b ...	1978	97776
the application of complement fixation to antibody weight estimates. ii.--to sheep erythrocytes.		1978	98098
activity of three 8-hydroxyquinoline derivatives against in vitro dental plaque.	three 8-hydroxyquinoline derivatives, assessed using an in vitro preformed dental plaque model system, were differentially inhibitory for four plaque-forming microorganisms.	1978	98105
infection in acute leukemia patients receiving oral nonabsorable antibiotics.	during a 20-month period all acute nonlymphocytic patients (87 patient trials) receiving cytotoxic chemotherapy were placed on an oral nonabsorbable antibiotic regimen consisting of gentamicin, vancomycin, and nystatin in addition to an intensive program of infection prevention aimed at reducing exogenously acquired and body-surface potential pathogens. although side effects of anorexia, diarrhea, and nausea were common, gentamicin-vancomycin-nystatin was ingested 80% of the study time. microbia ...	1978	98107
experimental coronary atherosclerosis in rabbits.		1978	98302
immunopathology of malaria.		1978	98476
pleiotropic effect of a rifampin-resistant mutation in bacillus subtilis.	rifampin-resistant (rifr) mutants were isolated spontaneously from bacillus subtilis strain 168. a fraction of the mutants did not grow on a minimal medium. a high concentration of one of the l-amino acids (glutamic acid, glutamine, arginine, proline, aspartic acid, or asparagine) was required to restore their growth on the medium. further analysis of one of the mutants (strain rf 161) suggested that the mutant is unable to use ammonia as a nitrogen source and requires amino acids instead. activ ...	1978	98517
formylation of initiator trna methionine in procaryotic protein synthesis: in vivo polarity in lactose operon expression.	eucaryotic and procaryotic organisms differ in two aspects of their translation machinery: polycistronic messengers are expressed as a sequence of individual proteins only in procaryotes, and the initiation of protein synthesis proceeds with an initiator trna which is found to be modified (formylated) in procaryotes and not in eucaryotes. in the present study, we show that formylation is required in vivo for the coordinate expression of the escherichia coli lactose operon. our experiments are co ...	1978	98518
altered mrna metabolism in ribonuclease iii-deficient strains of escherichia coli.	the metabolism of mrna from the lactose (lac) operon of escherichia coli has been studied in ribonuclease (rnase) iii-deficient strains (rnc-105). the induction lag for beta-galactosidase from the first gene was twice as long, and enzyme synthesis was reduced 10-fold in one such mutant compared with its isogenic rnc+ sister; in the original mutant strain ab301-105, synthesis of beta-galactosidase was not even detectable, although transduction analysis revealed the presence of a normal lac operon ...	1978	98520
a.d.a. recommendations to dhew on proposed changes in standards for long-term care facilities.		1978	98553
observations on acute gastric dilatation in nonhuman primates.	in the years 1967-1977 we diagnosed 23 cases of acute gastric dilatation in monkeys. fourteen of these animals were macaca mulatta, five macaca fascicularis, and one each of macaca nemestrina, aotus trivirgatus, saimiri sciureus, and colobus guereza. fourteen of the animals were males, nine were females, and all were adults or subadults. mortality was 78% (18 of 23 animals). thirteen of the animals had received on anesthetic, immobilizing, or tranquilizing drug 1-2 days before developing acute g ...	1978	98666
localised insertion of new cell wall in bacillus subtilis.		1978	98715
electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey.		1978	98733
reduced hepatic bilirubin uridine diphosphate glucuronyl transferase and uridine diphosphate glucose dehydrogenase activity in the human fetus.	hepatic bilirubin uridine diphosphate glucuronyl transferase (udpg-t) activity was 0.14 and 0.22 units in two fetuses aged 17 and 22 weeks, respectively, and less than 0.1 unit in 15 fetuses, aged 8--19 weeks compared to 0.68--1.99 units in 21 normal adults. hepatic uridine diphosphate glucose dehydrogenase (udpg-d) activity in 14 fetuses, aged 8--18 weeks, ranged from 6.2--15.0 units (mean = 11.3 +/- 0.7) compared to 28.8--49.2 units (mean = 39.6 +/- 2.5) in eight normal adults (p less than 0.0 ...	1978	98749
[some aspects relating to the aflatoxin generation during the self-heating of cereals].	in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ...	1978	98933
age-associated changes in the blood picture of the goat.		1978	98936
improved safety of splenoportography by plugging of the needle tract.	splenoportography, a useful preoperative diagnostic procedure in patients with portal hypertension, has been largely discontinued because of the risk of hemorrhage. we have used both ivalon and gelfoam in particle and plug form to plug the needle tract after splenoportography. initial studies were conducted on six dogs. plugging of the needle tract by injection of suspensions of small gelfoam or ivalon particles resulted in intravasation of these particles into the splenic vein. this was demonst ...	1978	98987
microradiographic demonstration of pyelolymphatic backflow in the porcine kidney.	pyelolymphatic backflow occurs when intrapelvic pressure rises acutely. although peripelvic and hilar lymphatics have occasionally been demonstrated during intravenous urography and retrograde pyelography, the patterns of intrarenal microlymphatic filling have not previously been studied radiographically in multipapillary kidneys. microradiography was performed after retrograde ureteral injections of barium sulfate suspension in recently excised pig kidneys. contrast filled the ducts of bellini ...	1978	98998
jaundice and breast-feeding among alaskan eskimo newborns.	the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ...	1978	99026
interferon inducing activity of polyinosinic acid.	although poly(i) is generally considered to be inactive as an interferon inducer, we have found several authentic poly(i) preparations to be effective inducers. their interferon inducing ability varied considerably from one cell system to another. in human diploid fibroblasts, primed with interferon and superinduced by cycloheximide and actinomycin d, all active poly(i) samples proved nearly as effective in inducing interferon as poly(i).poly(c). in primary rabbit kidney cell cultures, the activ ...	1978	99486
ultraviolet light-induction and photoreactivation of thymine dimers in a cyanobacterium, anacystis nidulans.	partially photoreactivable mutant of anacystis nidulans demonstrates partial photorepair of thymine dimers. the wild type which is completely photoreactivable at the conditions studied shows higher level of thymine dimer photolysis.	1978	100072
inverse correlation between species lifespan and capacity of cultured fibroblasts to convert benzo(a)pyrene to water-soluble metabolites.		1978	101383
purification and characterization of allergens from parietaria officinalis pollen.		1978	101439
[salmonellosis].		1978	101617
the surface properties of neisseria gonorrhoeae: topographical distribution of the outer membrane protein antigens.	gonococci were labelled with 125i using the lactoperoxidase system. the amount of label incorporated was similar with all strains including those which appeared capsulated. electrophoresis on sodium dodecyl sulphate-polyacrylamide gels revealed that the major proteins labelled were those found in outer membrane preparations. comparison of variants of one strain showed that the major outer membrane protein (protein i) was always present and heavily labelled. the second major protein (protein ii) ...	1978	102733
effect of cobalt-60 radiation on response to endodontic therapy in monkeys.	response of teeth that had received therapeutic doses of cobalt-60 radiation to endodontic therapy were investigated in three monkeys. the results indicated no appreciable effect of the irradiation on the response to root canal treatment aside from reduction in osteoblastic activity.	1978	103612
toxoplasma gondii: penetration into differentiating friend erythroleukemia cells.		1978	103745
[post-extrasystolic and post-pacing potentiation. i. experimental study of the isolated heart of the rabbit].		1978	88947
changes in immunological activity of rat lymphoid organs during pregnancy.	immune reactivity in lymhoid organs of rats during the last week of syngeneic (lewis: l x l) or allogeneic (females lewis x males wistar: l x w) pregnancy was compared with that found in non-pregnant animals. the thymus weight was slightly reduced and the response of thymic lymphocytes to phytohaemagglutinin and concanavalin a was slightly, but not significantly, elevated in pregnant rats. by contrast, the response of lymphoid cells from spleen and mesenteric lymph nodes to the mitogens was redu ...	1978	149623