Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| characterization of the doublesex gene within the culex pipiens complex suggests regulatory plasticity at the base of the mosquito sex determination cascade. | the doublesex gene controls somatic sexual differentiation of many metazoan species, including the malaria mosquito anopheles gambiae and the dengue and yellow fever vector aedes aegypti (diptera: culicidae). as in other studied dipteran dsx homologs, the gene maintains functionality via evolutionarily conserved protein domains and sex-specific alternative splicing. the upstream factors that regulate splicing of dsx and the manner in which they do so however remain variable even among closely re ... | 2015 | 26058583 |
| an unusual role for doublesex in sex determination in the dipteran sciara. | the gene doublesex, which is placed at the bottom of the sex-determination gene cascade, plays the ultimate discriminatory role for sex determination in insects. in all insects where this gene has been characterized, the dsx premessenger rna (pre-mrna) follows a sex-specific splicing pattern, producing male- and female-specific mrnas encoding the male-dsxm and female-dsxf proteins, which determine male and female development, respectively. this article reports the isolation and characterization ... | 2015 | 26063659 |
| a defensin from the model beetle tribolium castaneum acts synergistically with telavancin and daptomycin against multidrug resistant staphylococcus aureus. | the red flour beetle tribolium castaneum is a common insect pest and has been established as a model beetle to study insect development and immunity. this study demonstrates that defensin 1 from t. castaneum displays in vitro and in vivo antimicrobial activity against drug resistant staphylococcus aureus strains. the minimum inhibitory concentration (mic) of defensin 1 against 11 reference and clinical staphylococcal isolates was between 16-64 μg/ml. the putative mode of action of the defensin p ... | 2015 | 26062137 |
| assessing the epidemiological effect of wolbachia for dengue control. | dengue viruses cause more human morbidity and mortality than any other arthropod-borne virus. dengue prevention relies mainly on vector control; however, the failure of traditional methods has promoted the development of novel entomological approaches. although use of the intracellular bacterium wolbachia to control mosquito populations was proposed 50 years ago, only in the past decade has its use as a potential agent of dengue control gained substantial interest. here, we review evidence that ... | 2015 | 26051887 |
| analysing chemical attraction of gravid anopheles gambiae sensu stricto with modified bg-sentinel traps. | cues that guide gravid anopheles gambiae sensu lato to oviposition sites can be manipulated to create new strategies for monitoring and controlling malaria vectors. however, progress towards identifying such cues is slow in part due to the lack of appropriate tools for investigating long-range attraction to putative oviposition substrates. this study aimed to develop a relatively easy-to-use bioassay system that can effectively analyse chemical attraction of gravid anopheles gambiae sensu strict ... | 2015 | 26036270 |
| knowledge and beliefs about dengue transmission and their relationship with prevention practices in hermosillo, sonora. | dengue is an emerging threat in the u.s.-mexico border region. transmission has regularly occurred in sonora, mx since 1982 but it was not until 2014 that cities directly on the arizona-sonora border had local transmission. one of the closest urban areas to have regular seasonal transmission is hermosillo, sn, mx. developing a better understanding of the knowledge and perceptions of dengue in close geographic proximity to the border can identify areas to target for prevention and control measure ... | 2015 | 26090357 |
| multitasking roles of mosquito labrum in oviposition and blood feeding. | reception of odorants by two main head appendages, antennae and maxillary palps, is essential for insects' survival and reproduction. there is growing evidence in the literature suggesting that the proboscis is also an olfactory appendage and its function as an additional "antenna" has been previously proposed. we surmised that movements of the labrum toward a blood vessel might be chemically oriented and, if so, there should be odorant receptors expressed in the labrum. to test this hypothesis, ... | 2015 | 26578978 |
| field evaluation of the establishment potential of wmelpop wolbachia in australia and vietnam for dengue control. | introduced wolbachia bacteria can influence the susceptibility of aedes aegypti mosquitoes to arboviral infections as well as having detrimental effects on host fitness. previous field trials demonstrated that the wmel strain of wolbachia effectively and durably invades ae. aegypti populations. here we report on trials of a second strain, wmelpop-pgyp wolbachia, in field sites in northern australia (machans beach and babinda) and central vietnam (tri nguyen, hon mieu island), each with contrasti ... | 2015 | 26510523 |
| hormonal regulation of response to oxidative stress in insects-an update. | insects, like other organisms, must deal with a wide variety of potentially challenging environmental factors during the course of their life. an important example of such a challenge is the phenomenon of oxidative stress. this review summarizes the current knowledge on the role of adipokinetic hormones (akh) as principal stress responsive hormones in insects involved in activation of anti-oxidative stress response pathways. emphasis is placed on an analysis of oxidative stress experimentally in ... | 2015 | 26516847 |
| traditional medicine practices among community members with chronic kidney disease in northern tanzania: an ethnomedical survey. | in sub-saharan africa, chronic kidney disease (ckd) is being recognized as a non-communicable disease (ncd) with high morbidity and mortality. in countries like tanzania, people access many sources, including traditional medicines, to meet their healthcare needs for ncds, but little is known about traditional medicine practices among people with ckd. therefore, we sought to characterize these practices among community members with ckd in northern tanzania. | 2015 | 26499070 |
| bacteria endosymbiont, wolbachia, promotes parasitism of parasitoid wasp asobara japonica. | wolbachia is the most widespread endosymbiotic bacterium that manipulates reproduction of its arthropod hosts to enhance its own spread throughout host populations. infection with wolbachia causes complete parthenogenetic reproduction in many hymenoptera, producing only female offspring. the mechanism of such reproductive manipulation by wolbachia has been extensively studied. however, the effects of wolbachia symbiosis on behavioral traits of the hosts are scarcely investigated. the parasitoid ... | 2015 | 26492411 |
| the fucomic potential of mosquitoes: fucosylated n-glycan epitopes and their cognate fucosyltransferases. | fucoconjugates are key mediators of protein-glycan interactions in prokaryotes and eukaryotes. as examples, n-glycans modified with the non-mammalian core α1,3-linked fucose have been detected in various organisms ranging from plants to insects and are immunogenic in mammals. the rabbit polyclonal antibody raised against plant horseradish peroxidase (anti-hrp) is able to recognize the α1,3-linked fucose epitope and is also known to specifically stain neural tissues in the fruit fly drosophila me ... | 2015 | 26617287 |
| self-experimenting physicians: mavericks or martyrs? | 2015 | 26629369 | |
| fast evolutionary rates associated with functional loss in class i glucose transporters of schistosoma mansoni. | the trematode parasite, schistosoma mansoni, has evolved to switch from oxidative phosphorylation to glycolysis in the presence of glucose immediately after invading the human host. this metabolic switch is dependent on extracellular glucose concentration. four glucose transporters are encoded in the genome of s. mansoni, however, only two were shown to facilitate glucose diffusion. | 2015 | 26584526 |
| insect resistance to bacillus thuringiensis toxin cry2ab is conferred by mutations in an abc transporter subfamily a protein. | the use of conventional chemical insecticides and bacterial toxins to control lepidopteran pests of global agriculture has imposed significant selection pressure leading to the rapid evolution of insecticide resistance. transgenic crops (e.g., cotton) expressing the bt cry toxins are now used world wide to control these pests, including the highly polyphagous and invasive cotton bollworm helicoverpa armigera. since 2004, the cry2ab toxin has become widely used for controlling h. armigera, often ... | 2015 | 26583651 |
| el niño-southern oscillation, local weather and occurrences of dengue virus serotypes. | severe dengue fever is usually associated with secondary infection by a dengue virus (denv) serotype (1 to 4) that is different to the serotype of the primary infection. dengue outbreaks only occur following importations of denv in cairns, australia. however, the majority of imported cases do not result in autochthonous transmission in cairns. although denv transmission is strongly associated with the el niño-southern oscillation (enso) climate cycle and local weather conditions, the frequency a ... | 2015 | 26581295 |
| insectbase: a resource for insect genomes and transcriptomes. | the genomes and transcriptomes of hundreds of insects have been sequenced. however, insect community lacks an integrated, up-to-date collection of insect gene data. here, we introduce the first release of insectbase, available online at http://www.insect-genome.com. the database encompasses 138 insect genomes, 116 insect transcriptomes, 61 insect gene sets, 36 gene families of 60 insects, 7544 mirnas of 69 insects, 96,925 pirnas of drosophila melanogaster and chilo suppressalis, 2439 lncrna of n ... | 2015 | 26578584 |
| genome of rhodnius prolixus, an insect vector of chagas disease, reveals unique adaptations to hematophagy and parasite infection. | rhodnius prolixus not only has served as a model organism for the study of insect physiology, but also is a major vector of chagas disease, an illness that affects approximately seven million people worldwide. we sequenced the genome of r. prolixus, generated assembled sequences covering 95% of the genome (∼ 702 mb), including 15,456 putative protein-coding genes, and completed comprehensive genomic analyses of this obligate blood-feeding insect. although immune-deficiency (imd)-mediated immune ... | 2015 | 26627243 |
| screening analogs of β-og pocket binder as fusion inhibitor of dengue virus 2. | dengue is an infectious disease caused by dengue virus (denv) and transmitted between human hosts by mosquitoes. recently, indonesia was listed as a country with the highest cases of dengue by the association of southeast asian nations. the current treatment for dengue disease is supportive therapy; there is no antiviral drug available in the market against dengue. therefore, a research on antiviral drug against dengue is very important, especially to prevent outbreak explosion. in this research ... | 2015 | 26617459 |
| surveillance of dengue vectors using spatio-temporal bayesian modeling. | at present, dengue control focuses on reducing the density of the primary vector for the disease, aedes aegypti, which is the only vulnerable link in the chain of transmission. the use of new approaches for dengue entomological surveillance is extremely important, since present methods are inefficient. with this in mind, the present study seeks to analyze the spatio-temporal dynamics of a. aegypti infestation with oviposition traps, using efficient computational methods. these methods will allow ... | 2015 | 26566610 |
| negative feedbacks by isoprenoids on a mevalonate kinase expressed in the corpora allata of mosquitoes. | juvenile hormones (jh) regulate development and reproductive maturation in insects. jhs are synthesized through the mevalonate pathway (mvap), an ancient metabolic pathway present in the three domains of life. mevalonate kinase (mvk) is a key enzyme in the mvap. mvk catalyzes the synthesis of phosphomevalonate (pm) by transferring the γ-phosphoryl group from atp to the c5 hydroxyl oxygen of mevalonic acid (ma). despite the importance of mvks, these enzymes have been poorly characterized in insec ... | 2015 | 26566274 |
| rna-seq de novo assembly reveals differential gene expression in glossina palpalis gambiensis infected with trypanosoma brucei gambiense vs. non-infected and self-cured flies. | trypanosoma brucei gambiense (tbg), causing the sleeping sickness chronic form, completes its developmental cycle within the tsetse fly vector glossina palpalis gambiensis (gpg) before its transmission to humans. within the framework of an anti-vector disease control strategy, a global gene expression profiling of trypanosome infected (susceptible), non-infected, and self-cured (refractory) tsetse flies was performed, on their midguts, to determine differential genes expression resulting from in ... | 2015 | 26617594 |
| immunogenicity and protective efficacy of brugia malayi heavy chain myosin as homologous dna, protein and heterologous dna/protein prime boost vaccine in rodent model. | we earlier demonstrated the immunoprophylactic efficacy of recombinant heavy chain myosin (bm-myo) of brugia malayi (b. malayi) in rodent models. in the current study, further attempts have been made to improve this efficacy by employing alternate approaches such as homologous dna (pcd-myo) and heterologous dna/protein prime boost (pcd-myo+bm-myo) in balb/c mouse model. the gene bm-myo was cloned in a mammalian expression vector pcdna 3.1(+) and protein expression was confirmed in mammalian vero ... | 2015 | 26560102 |
| genomic mining reveals deep evolutionary relationships between bornaviruses and bats. | bats globally harbor viruses in order mononegavirales, such as lyssaviruses and henipaviruses; however, little is known about their relationships with bornaviruses. previous studies showed that viral fossils of bornaviral origin are embedded in the genomes of several mammalian species such as primates, indicative of an ancient origin of exogenous bornaviruses. in this study, we mined the available 10 bat genomes and recreated a clear evolutionary relationship of endogenous bornaviral elements an ... | 2015 | 26569285 |
| dispersal of engineered male aedes aegypti mosquitoes. | aedes aegypti, the principal vector of dengue fever, have been genetically engineered for use in a sterile insect control programme. to improve our understanding of the dispersal ecology of mosquitoes and to inform appropriate release strategies of 'genetically sterile' male aedes aegypti detailed knowledge of the dispersal ability of the released insects is needed. | 2015 | 26554922 |
| ran involved in the development and reproduction is a potential target for rna-interference-based pest management in nilaparvata lugens. | ran (rangtpase) in insects participates in the 20-hydroxyecdysone signal transduction pathway in which downstream genes, ftz-f1, krüppel-homolog 1 (kr-h1) and vitellogenin, are involved. a putative ran gene (nlran) was cloned from nilaparvata lugens, a destructive phloem-feeding pest of rice. nlran has the typical ran primary structure features that are conserved in insects. nlran showed higher mrna abundance immediately after molting and peaked in newly emerged female adults. among the examined ... | 2015 | 26554926 |
| new genetic regulators question relevance of abundant yolk protein production in c. elegans. | vitellogenesis or maternal yolk formation is considered critical to the reproduction of egg-laying animals. in invertebrates, however, most of its regulatory genes are still unknown. via a combined mapping and whole-genome sequencing strategy, we performed a forward genetic screen to isolate novel regulators of yolk production in the nematode model system caenorhabditis elegans. in addition to isolating new alleles of rab-35, rab-10 and m04f3.2, we identified five mutant alleles corresponding to ... | 2015 | 26553710 |
| the prevention and control of dengue after typhoon haiyan. | many of the areas in the philippines affected by typhoon haiyan are endemic for dengue; therefore, dengue prevention was a priority in the initial post-disaster risk assessment. we describe the dengue prevention and response strategies applied after haiyan. | 2015 | 26767138 |
| sirna-mediated silencing of doublesex during female development of the dengue vector mosquito aedes aegypti. | the development of sex-specific traits, including the female-specific ability to bite humans and vector disease, is critical for vector mosquito reproduction and pathogen transmission. doublesex (dsx), a terminal transcription factor in the sex determination pathway, is known to regulate sex-specific gene expression during development of the dengue fever vector mosquito aedes aegypti. here, the effects of developmental sirna-mediated dsx silencing were assessed in adult females. targeting of dsx ... | 2015 | 26544686 |
| identification of putative olfactory genes from the oriental fruit moth grapholita molesta via an antennal transcriptome analysis. | the oriental fruit moth, grapholita molesta, is an extremely important oligophagous pest species of stone and pome fruits throughout the world. as a host-switching species, adult moths, especially females, depend on olfactory cues to a large extent in locating host plants, finding mates, and selecting oviposition sites. the identification of olfactory genes can facilitate investigation on mechanisms for chemical communications. | 2015 | 26540284 |
| conserved genetic interactions between ciliopathy complexes cooperatively support ciliogenesis and ciliary signaling. | mutations in genes encoding cilia proteins cause human ciliopathies, diverse disorders affecting many tissues. individual genes can be linked to ciliopathies with dramatically different phenotypes, suggesting that genetic modifiers may participate in their pathogenesis. the ciliary transition zone contains two protein complexes affected in the ciliopathies meckel syndrome (mks) and nephronophthisis (nphp). the bbsome is a third protein complex, affected in the ciliopathy bardet-biedl syndrome (b ... | 2015 | 26540106 |
| molecular characterization and differential expression of an olfactory receptor gene family in the white-backed planthopper sogatella furcifera based on transcriptome analysis. | the white-backed planthopper, sogatella furcifera, a notorious rice pest in asia, employs host plant volatiles as cues for host location. in insects, odor detection is mediated by two types of olfactory receptors: odorant receptors (ors) and ionotropic receptors (irs). in this study, we identified 63 sfurors and 14 sfurirs in s. furcifera based on sequences obtained from the head transcriptome and bioinformatics analysis. the motif-pattern of 130 hemiptera ors indicated an apparent differentiati ... | 2015 | 26540266 |
| quantification of ns1 dengue biomarker in serum via optomagnetic nanocluster detection. | dengue is a tropical vector-borne disease without cure or vaccine that progressively spreads into regions with temperate climates. diagnostic tools amenable to resource-limited settings would be highly valuable for epidemiologic control and containment during outbreaks. here, we present a novel low-cost automated biosensing platform for detection of dengue fever biomarker ns1 and demonstrate it on ns1 spiked in human serum. magnetic nanoparticles (mnps) are coated with high-affinity monoclonal a ... | 2015 | 26536916 |
| impacts of el niño southern oscillation and indian ocean dipole on dengue incidence in bangladesh. | dengue dynamics are driven by complex interactions between hosts, vectors and viruses that are influenced by environmental and climatic factors. several studies examined the role of el niño southern oscillation (enso) in dengue incidence. however, the role of indian ocean dipole (iod), a coupled ocean atmosphere phenomenon in the indian ocean, which controls the summer monsoon rainfall in the indian region, remains unexplored. here, we examined the effects of enso and iod on dengue incidence in ... | 2015 | 26537857 |
| mitochondrial dna variants help monitor the dynamics of wolbachia invasion into host populations. | wolbachia is the most widespread endosymbiotic bacterium of insects and other arthropods that can rapidly invade host populations. deliberate releases of wolbachia into natural populations of the dengue fever mosquito, aedes aegypti, are used as a novel biocontrol strategy for dengue suppression. invasion of wolbachia through the host population relies on factors such as high fidelity of the endosymbiont transmission and limited immigration of uninfected individuals, but these factors can be dif ... | 2015 | 26531251 |
| new linear antiplasmodial peptides related to angiotensin ii. | antiplasmodial activities of angiotensin ii and its analogues have been extensively investigated in plasmodium gallinaceum and plasmodium falciparum parasite species. due to its vasoconstrictor property angiotensin ii cannot be used as an anti-malarial drug. | 2015 | 26537730 |
| the evolutionary landscape of intergenic trans-splicing events in insects. | to explore the landscape of intergenic trans-splicing events and characterize their functions and evolutionary dynamics, we conduct a mega-data study of a phylogeny containing eight species across five orders of class insecta, a model system spanning 400 million years of evolution. a total of 1,627 trans-splicing events involving 2,199 genes are identified, accounting for 1.58% of the total genes. homology analysis reveals that mod(mdg4)-like trans-splicing is the only conserved event that is co ... | 2015 | 26521696 |
| human odorant reception in the common bed bug, cimex lectularius. | the common bed bug cimex lectularius is a temporary ectoparasite on humans and currently resurgent in many developed countries. the ability of bed bugs to detect human odorants in the environment is critical for their host-seeking behavior. this study deciphered the chemical basis of host detection by investigating the neuronal response of olfactory sensilla to 104 human odorants using single sensillum recording and characterized the electro-physiological responses of bed bug odorant receptors t ... | 2015 | 26522967 |
| partial characterization of venom from the colombian spider phoneutria boliviensis (aranae:ctenidae). | we report on the first studies on the characterization of venom from phoneutria boliviensis (aranae:ctenidae) (f. o. pickard-cambridge, 1897), done with colombian species. after the electrostimulation extraction process, the venom showed physicochemical properties corresponding to a colorless and water-soluble liquid with a density of 0.86 mg/ml and 87% aqueous content. p. boliviensis venom and rp-hplc fractions showed hemolytic activity and hydrolyzed the synthetic substrate 4-nitro-3-octanoylo ... | 2015 | 26264023 |
| enhanced cuticular penetration as the mechanism for synergy of insecticidal constituents of rosemary essential oil in trichoplusia ni. | synergistic interactions between constituents of essential oils have been reported for several areas of research. in the present study, mechanisms that could explain the synergistic action of the two major insecticidal constituents of rosemary oil, 1,8-cineole and camphor against the cabbage looper, trichoplusia ni were investigated. 1,8-cineole was more toxic than camphor when applied topically to larvae, and when coadministered in their ratio naturally occurring in rosemary oil, the binary mix ... | 2015 | 26223769 |
| traditional uses, phytochemistry, and bioactivities of cananga odorata (ylang-ylang). | ylang-ylang (cananga odorata hook. f. & thomson) is one of the plants that are exploited at a large scale for its essential oil which is an important raw material for the fragrance industry. the essential oils extracted via steam distillation from the plant have been used mainly in cosmetic industry but also in food industry. traditionally, c. odorata is used to treat malaria, stomach ailments, asthma, gout, and rheumatism. the essential oils or ylang-ylang oil is used in aromatherapy and is bel ... | 2015 | 26294929 |
| the asian rice gall midge (orseolia oryzae) mitogenome has evolved novel gene boundaries and tandem repeats that distinguish its biotypes. | the complete mitochondrial genome of the asian rice gall midge, orseolia oryzae (diptera; cecidomyiidae) was sequenced, annotated and analysed in the present study. the circular genome is 15,286 bp with 13 protein-coding genes, 22 trnas and 2 ribosomal rna genes, and a 578 bp non-coding control region. all protein coding genes used conventional start codons and terminated with a complete stop codon. the genome presented many unusual features: (1) rearrangement in the order of trnas as well as pr ... | 2015 | 26226163 |
| two inwardly rectifying potassium channels, irk1 and irk2, play redundant roles in drosophila renal tubule function. | inwardly rectifying potassium channels play essential roles in renal physiology across phyla. barium-sensitive k(+) conductances are found on the basolateral membrane of a variety of insect malpighian (renal) tubules, including drosophila melanogaster. we found that barium decreases the lumen-positive transepithelial potential difference in isolated perfused drosophila tubules and decreases fluid secretion and transepithelial k(+) flux. in those insect species in which it has been studied, trans ... | 2015 | 26224687 |
| chemical component and proteomic study of the amphibalanus (= balanus) amphitrite shell. | as typical biofoulers, barnacles possess hard shells and cause serious biofouling problems. in this study, we analyzed the protein component of the barnacle amphibalanus (= balanus) amphitrite shell using gel-based proteomics. the results revealed 52 proteins in the a. amphitrite shell. among them, 40 proteins were categorized into 11 functional groups based on kog database, and the remaining 12 proteins were unknown. besides the known proteins in barnacle shell (sipc, carbonic anhydrase and aci ... | 2015 | 26222041 |
| weather regulates location, timing, and intensity of dengue virus transmission between humans and mosquitoes. | dengue is one of the most aggressively expanding mosquito-transmitted viruses. the human burden approaches 400 million infections annually. complex transmission dynamics pose challenges for predicting location, timing, and magnitude of risk; thus, models are needed to guide prevention strategies and policy development locally and globally. weather regulates transmission-potential via its effects on vector dynamics. an important gap in understanding risk and roadblock in model development is an e ... | 2015 | 26222979 |
| transcriptional analysis of susceptible and resistant european corn borer strains and their response to cry1f protoxin. | despite a number of recent reports of insect resistance to transgenic crops expressing insecticidal toxins from bacillus thuringiensis (bt), little is known about the mechanism of resistance to these toxins. the purpose of this study is to identify genes associated with the mechanism of cry1f toxin resistance in european corn borer (ostrinia nubilalis hübner). for this, we compared the global transcriptomic response of laboratory selected resistant and susceptible o. nubilalis strain to cry1f to ... | 2015 | 26220297 |
| in vitro and in vivo host range of anopheles gambiae densovirus (agdnv). | agdnv is a powerful gene transduction tool and potential biological control agent for anopheles mosquitoes. using a gfp reporter virus system, we investigated agdnv host range specificity in four arthropod cell lines (derived from an. gambiae, aedes albopictus and drosophila melanogaster) and six mosquito species from 3 genera (an. gambiae, an. arabiensis, an. stephensi, ae. albopictus, ae. aegypti and culex tarsalis). in vitro, efficient viral invasion, replication and gfp expression was only o ... | 2015 | 26220140 |
| mammalian cochlea as a physics guided evolution-optimized hearing sensor. | nonlinear physics plays an essential role in hearing. we demonstrate on a mesoscopic description level that during the evolutionary perfection of the hearing sensor, nonlinear physics led to the unique design of the cochlea observed in mammals, and that this design requests as a consequence the perception of pitch. our insight challenges the view that mostly genetics is responsible for the uniformity of the construction of the mammalian hearing sensor. our analysis also suggests that scaleable a ... | 2015 | 26216397 |
| a novel laminin β gene bmlanb1-w regulates wing-specific cell adhesion in silkworm, bombyx mori. | laminins are important basement membrane (bm) components with crucial roles in development. the numbers of laminin isoforms in various organisms are determined by the composition of the different α, β, and γ chains, and their coding genes, which are variable across spieces. in insects, only two α, one β, and one γ chains have been identified thus far. here, we isolated a novel laminin β gene, bmlanb1-w, by positional cloning of the mutant (crayfish, cf) with blistered wings in silkworm. gene str ... | 2015 | 26212529 |
| acute toxicity and dermal and eye irritation of the aqueous and hydroalcoholic extracts of the seeds of "zapote" pouteria mammosa (l.) cronquist. | the common use of pouteria mammosa (l.) cronquist, "mamey or zapote," in food and ethnobotanic medicine shows its low or absent toxicity as fruit extracts prepared from seeds. however, it is essential to conduct security trials to scientifically support their use in drug therapy. this study evaluated the aqueous and hydroalcoholic extract (25%) acute oral toxicity, obtained from the seeds of p. mammosa, in sprague dawley rats and dermal and eye irritability in new zealand rabbits. the 404 and 40 ... | 2015 | 26273696 |
| correction: evaluation of a push-pull approach for aedes aegypti (l.) using a novel dispensing system for spatial repellents in the laboratory and in a semi-field environment. | 2015 | 26207826 | |
| characterization of the honeybee amnav1 channel and tools to assess the toxicity of insecticides. | pollination is important for both agriculture and biodiversity. for a significant number of plants, this process is highly, and sometimes exclusively, dependent on the pollination activity of honeybees. the large numbers of honeybee colony losses reported in recent years have been attributed to colony collapse disorder. various hypotheses, including pesticide overuse, have been suggested to explain the disorder. using the xenopus oocytes expression system and two microelectrode voltage-clamp, we ... | 2015 | 26202396 |
| association between three mutations, f1565c, v1023g and s996p, in the voltage-sensitive sodium channel gene and knockdown resistance in aedes aegypti from yogyakarta, indonesia. | mutations in the voltage-sensitive sodium channel gene (vssc) have been identified in aedes aegypti and some have been associated with pyrethroid insecticide resistance. whether these mutations cause resistance, alone or in combination with other alleles, remains unclear, but must be understood if mutations are to become markers for resistance monitoring. we describe high resolution melt (hrm) genotyping assays for assessing mutations found in ae. aegypti in indonesia (f1565c, v1023g, s996p) and ... | 2015 | 26463408 |
| combination immunotherapy in the treatment of chronic bilateral panuveitis and uveitic glaucoma during acute dengue fever infection in the caribbean. | ocular manifestations of the dengue fever virus include bilateral panuveitis that can occur after the acute systemic infection has resolved. in most reported cases, the inflammation resolves with topical or systemic steroid therapy. we report a case of chronic, refractory bilateral panuveitis and uveitic glaucoma that began during the acute phase of the systemic infection and required treatment with oral steroids, multiple steroid-sparing agents, and surgical therapy for glaucoma. | 2015 | 26229512 |
| application of wmelpop wolbachia strain to crash local populations of aedes aegypti. | the endosymbiotic bacteria wolbachia pipientis (wmel strain) has been successfully established in several populations of aedes aegypti, the primary dengue vector. the virulent wolbachia strain wmelpop is known to cause several pathological impacts (increased egg mortality, life shortening, etc.) reducing overall fitness in the mosquito ae. aegypti. increased egg mortality could substantially reduce egg banks in areas with a lengthy monsoonal dry season, and be employed to eliminate local populat ... | 2015 | 26204449 |
| scrutinizing the immune defence inventory of camponotus floridanus applying total transcriptome sequencing. | defence mechanisms of organisms are shaped by their lifestyle, environment and pathogen pressure. carpenter ants are social insects which live in huge colonies comprising genetically closely related individuals in high densities within nests. this lifestyle potentially facilitates the rapid spread of pathogens between individuals. in concert with their innate immune system, social insects may apply external immune defences to manipulate the microbial community among individuals and within nests. ... | 2015 | 26198742 |
| stress responses of small heat shock protein genes in lepidoptera point to limited conservation of function across phylogeny. | the small heat shock protein (shsp) family is thought to play an important role in protein refolding and signal transduction, and thereby protect organisms from stress. however little is known about shsp function and conservation across phylogenies. in the current study, we provide a comprehensive assessment of small hsp genes and their stress responses in the oriental fruit moth (ofm), grapholita molesta. fourteen small heat shock proteins of ofm clustered with related hsps in other lepidoptera ... | 2015 | 26196395 |
| spatial distribution of dengue in a brazilian urban slum setting: role of socioeconomic gradient in disease risk. | few studies of dengue have shown group-level associations between demographic, socioeconomic, or geographic characteristics and the spatial distribution of dengue within small urban areas. this study aimed to examine whether specific characteristics of an urban slum community were associated with the risk of dengue disease. | 2015 | 26196686 |
| nonfunctional ingestion of plant mirnas in silkworm revealed by digital droplet pcr and transcriptome analysis. | since a plant mirna (mir168) cross-regulating a mammalian transcript was reported, mirna-mediated cross-kingdom communication has become one of the most compelling but controversial topics. in the present study, we used silkworm and mulberry, which is a model for studies on the interactions between the insect and its host plant, to address whether mirna-mediated cross-kingdom communication is a common phenomenon. the results of ta clone, sanger sequencing and droplet digital pcr demonstrated tha ... | 2015 | 26195298 |
| reception of odors and repellents in mosquitoes. | mosquitoes use their sense of smell to find hosts, nectar, and oviposition sites, and to avoid repellents. a small number of mosquito species are adapted to feed on humans and have a major impact on public health by transmitting diseases such as malaria, dengue and filariasis. the application of odorants for behavioral control has not been fully realized yet due to complexity of the mosquito olfactory system. recent progress in molecular and computational tools has enabled rigorous investigation ... | 2015 | 26202080 |
| a new membrane lipid raft gene spflt-1 facilitating the endocytosis of vibrio alginolyticus in the crab scylla paramamosain. | pathogens can enter their host cells by way of endocytosis in which the membrane lipid raft gene flotillins are probably involved in the invasion process and this is an important way to cause infection. in this study, a new gene spflt-1 was identified in scylla paramamosain, which shared high identity with the flotillin-1 of other species. the spflt-1 gene was widely distributed in tissues and showed the highest level of mrna transcripts in the hemocytes. this gene might be a maternal gene based ... | 2015 | 26186350 |
| mapping of the sequences directing localization of the drosophila germ cell-expressed protein (gce). | drosophila melanogaster germ cell-expressed protein (gce) belongs to the family of bhlh-pas transcription factors that are the regulators of gene expression networks that determine many physiological and developmental processes. gce is a homolog of d. melanogaster methoprene tolerant protein (met), a key mediator of anti-metamorphic signaling in insects and the putative juvenile hormone receptor. recently, it has been shown that the functions of met and gce are only partially redundant and tissu ... | 2015 | 26186223 |
| predicting scenarios for successful autodissemination of pyriproxyfen by malaria vectors from their resting sites to aquatic habitats; description and simulation analysis of a field-parameterizable model. | large-cage experiments indicate pyriproxifen (ppf) can be transferred from resting sites to aquatic habitats by anopheles arabiensis--malaria vector mosquitoes to inhibit emergence of their own offspring. ppf coverage is amplified twice: (1) partial coverage of resting sites with ppf contamination results in far higher contamination coverage of adult mosquitoes because they are mobile and use numerous resting sites per gonotrophic cycle, and (2) even greater contamination coverage of aquatic hab ... | 2015 | 26186730 |
| mosquitoes use vision to associate odor plumes with thermal targets. | all moving animals, including flies, sharks, and humans, experience a dynamic sensory landscape that is a function of both their trajectory through space and the distribution of stimuli in the environment. this is particularly apparent for mosquitoes, which use a combination of olfactory, visual, and thermal cues to locate hosts. mosquitoes are thought to detect suitable hosts by the presence of a sparse co₂ plume, which they track by surging upwind and casting crosswind. upon approach, local cu ... | 2015 | 26190071 |
| bacterial exposure at the larval stage induced sexual immune dimorphism and priming in adult aedes aegypti mosquitoes. | gender differences in the immune response of insects are driven by natural selection for females and sexual selection for males. these natural forces entail a multitude of extrinsic and intrinsic factors involved in a genotype-environment interaction that results in sex-biased expression of the genes shared by males and females. however, little is known about how an infection at a particular ontogenetic stage may influence later stages, or how it may impact sexual immune dimorphism. using aedes ... | 2015 | 26181517 |
| pest control and resistance management through release of insects carrying a male-selecting transgene. | development and evaluation of new insect pest management tools is critical for overcoming over-reliance upon, and growing resistance to, synthetic, biological and plant-expressed insecticides. for transgenic crops expressing insecticidal proteins from the bacterium bacillus thuringiensis ('bt crops') emergence of resistance is slowed by maintaining a proportion of the crop as non-bt varieties, which produce pest insects unselected for resistance. while this strategy has been largely successful, ... | 2015 | 26179401 |
| web platform using digital image processing and geographic information system tools: a brazilian case study on dengue. | dengue fever is endemic in asia, the americas, the east of the mediterranean and the western pacific. according to the world health organization, it is one of the diseases of greatest impact on health, affecting millions of people each year worldwide. a fast detection of increases in populations of the transmitting vector, the aedes aegypti mosquito, is essential to avoid dengue outbreaks. unfortunately, in several countries, such as brazil, the current methods for detecting populations changes ... | 2015 | 26178732 |
| mechanism of ammonia excretion in the freshwater leech nephelopsis obscura: characterization of a primitive rh protein and effects of high environmental ammonia. | remarkably little is known about nitrogenous excretion in freshwater invertebrates. in the current study, the nitrogen excretion mechanism in the carnivorous ribbon leech, nephelopsis obscura, was investigated. excretion experiments showed that the ribbon leech is ammonotelic, excreting 166.0 ± 8.6 nmol·grams fresh weight (gfw)(-1)·h(-1) ammonia and 14.7 ± 1.9 nmol·gfw(-1)·h(-1) urea. exposure to high and low ph hampered and enhanced, respectively, ammonia excretion rates, indicating an acid-lin ... | 2015 | 26180186 |
| a corpora allata farnesyl diphosphate synthase in mosquitoes displaying a metal ion dependent substrate specificity. | farnesyl diphosphate synthase (fpps) is a key enzyme in isoprenoid biosynthesis, it catalyzes the head-to-tail condensation of dimethylallyl diphosphate (dmapp) with two molecules of isopentenyl diphosphate (ipp) to generate farnesyl diphosphate (fpp), a precursor of juvenile hormone (jh). in this study, we functionally characterized an aedes aegypti fpps (aafpps) expressed in the corpora allata. aafpps is the only fpps gene present in the genome of the yellow fever mosquito, it encodes a 49.6 k ... | 2015 | 26188328 |
| stimulating anopheles gambiae swarms in the laboratory: application for behavioural and fitness studies. | male anopheles mosquitoes that swarm rely in part on features of the environment including visual stimuli to locate swarms. swarming is believed to be the primary behaviour during which mating occurs in the field, but is not a common behaviour in the laboratory. features that stimulate male anopheles gambiae g3 strain swarming were created in novel large indoor cages. | 2015 | 26169677 |
| antiviral and antioxidant activities of sulfated galactomannans from plants of caatinga biome. | dengue represents a serious social and economic public health problem; then trying to contribute to improve its control, the objective of this research was to develop phytoterapics for dengue treatment using natural resources from caatinga biome. galactomannans isolated from adenanthera pavonina l., caesalpinia ferrea mart., and dimorphandra gardneriana tull were chemically sulfated in order to evaluate the antioxidant, and antiviral activities and the role in the inhibition of virus denv-2 in v ... | 2015 | 26257815 |
| alternative nf-κb isoforms in the drosophila neuromuscular junction and brain. | the drosophila nf-κb protein dorsal is expressed at the larval neuromuscular junction, where its expression appears unrelated to known dorsal functions in embryonic patterning and innate immunity. using confocal microscopy with domain-specific antisera, we demonstrate that larval muscle expresses only the b isoform of dorsal, which arises by intron retention. we find that dorsal b interacts with and stabilizes cactus at the neuromuscular junction, but exhibits cactus independent localization and ... | 2015 | 26167685 |
| bombyx e75 isoforms display stage- and tissue-specific responses to 20-hydroxyecdysone. | resulted from alternative splicing of the 5' exons, the nuclear receptor gene e75 in the silkworm, bombyx mori, processes three mrna isoforms, bme75a, bme75b and bme75c. from the early 5(th) larval instar to the prepupal stages, bme75a mrna and protein levels in the prothoracic glands display developmental profiles similar to ecdysteroid titer. in the fat body, mrna levels but not protein levels of all three bme75 isoforms correlate with ecdysteroid titer; moreover, proteins of all three bme75 i ... | 2015 | 26166384 |
| genetic evidence for function of the bhlh-pas protein gce/met as a juvenile hormone receptor. | juvenile hormones (jhs) play a major role in controlling development and reproduction in insects and other arthropods. synthetic jh-mimicking compounds such as methoprene are employed as potent insecticides against significant agricultural, household and disease vector pests. however, a receptor mediating effects of jh and its insecticidal mimics has long been the subject of controversy. the bhlh-pas protein methoprene-tolerant (met), along with its drosophila melanogaster paralog germ cell-expr ... | 2015 | 26161662 |
| the seasonal reproduction number of dengue fever: impacts of climate on transmission. | background. dengue fever is a mosquito-borne viral disease and a regular epidemic in thailand. the peak of the dengue epidemic period is around june to august during the rainy season. it is believed that climate is an important factor for dengue transmission. method. a mathematical model for vector-host infectious disease was used to calculate the impacts of climate to the transmission of dengue virus. in this study, the data of climate and dengue fever cases were derived from chiang mai during ... | 2015 | 26213648 |
| temporal coordination of carbohydrate metabolism during mosquito reproduction. | hematophagous mosquitoes serve as vectors of multiple devastating human diseases, and many unique physiological features contribute to the incredible evolutionary success of these insects. these functions place high-energy demands on a reproducing female mosquito, and carbohydrate metabolism (cm) must be synchronized with these needs. functional analysis of metabolic gene profiling showed that major cm pathways, including glycolysis, glycogen and sugar metabolism, and citrate cycle, are dramatic ... | 2015 | 26158648 |
| evolutionary decay and the prospects for long-term disease intervention using engineered insect vectors. | after a long history of applying the sterile insect technique to suppress populations of disease vectors and agricultural pests, there is growing interest in using genetic engineering both to improve old methods and to enable new methods. the two goals of interventions are to suppress populations, possibly eradicating a species altogether, or to abolish the vector's competence to transmit a parasite. new methods enabled by genetic engineering include the use of selfish genes toward either goal a ... | 2015 | 26160736 |
| evidence of limited polyandry in a natural population of aedes aegypti. | the mosquito aedes aegypti is a vector of yellow fever, dengue, and chikungunya. control of the insect is crucial to stop the spread of dengue and chikungunya, so it is critically important to understand its mating behavior. primarily, based on laboratory behavior, it has long been assumed that ae. aegypti females mate once in their lifetime. however, multiple inseminations have been observed in semi-field and laboratory settings, and in closely related species. here, we report the first evidenc ... | 2015 | 25870424 |
| simulated seasonal photoperiods and fluctuating temperatures have limited effects on blood feeding and life history in aedes triseriatus (diptera: culicidae). | biotic and abiotic factors change seasonally and impact life history in temperate-zone ectotherms. temperature and photoperiod are factors that change in predictable ways. most studies testing for effects of temperature on vectors use constant temperatures and ignore potential correlated effects of photoperiod. in two experiments, we tested for effects of larval rearing environments creating ecologically relevant temperatures and photoperiods simulating early and late season conditions (june and ... | 2015 | 26336255 |
| 20-hydroxyecdysone stimulation of juvenile hormone biosynthesis by the mosquito corpora allata. | juvenile hormone iii (jh) is synthesized by the corpora allata (ca) and plays a key role in mosquito development and reproduction. jh titer decreases in the last instar larvae allowing pupation and metamorphosis to progress. as the anti-metamorphic role of jh comes to an end, the ca of the late pupa (or pharate adult) becomes again "competent" to synthesize jh, which plays an essential role orchestrating reproductive maturation. 20-hydroxyecdysone (20e) prepares the pupae for ecdysis, and would ... | 2015 | 26255691 |
| building better environmental risk assessments. | risk assessment is a reasoned, structured approach to address uncertainty based on scientific and technical evidence. it forms the foundation for regulatory decision-making, which is bound by legislative and policy requirements, as well as the need for making timely decisions using available resources. in order to be most useful, environmental risk assessments (eras) for genetically modified (gm) crops should provide consistent, reliable, and transparent results across all types of gm crops, tra ... | 2015 | 26301217 |
| better to be in bad company than to be alone? aedes vectors respond differently to breeding site quality in the presence of others. | this study focuses on two competing species, aedes aegypti and aedes albopictus (diptera: culicidae), both invasive mosquitoes of the new world. context-specific competition between immature forms inside containers seems to be an important determinant of the coexistence or displacement of each species in different regions of the world. here, competition experiments developed at low density (one, two or three larvae) and receiving four different resource food concentration, were designed to test ... | 2015 | 26244511 |
| association among house infestation index, dengue incidence, and sociodemographic indicators: surveillance using geographic information system. | we identified dengue transmission areas by using the geographic information systems located at local surveillance units of the itaboraí municipality in state of rio de janeiro. we considered the association among the house infestation index, the disease incidence, and sociodemographic indicators during a prominent dengue outbreak in 2007 and 2008. | 2015 | 26243266 |
| drosophila kash-domain protein klarsicht regulates microtubule stability and integrin receptor localization during collective cell migration. | during collective migration of the drosophila embryonic salivary gland, cells rearrange to form a tube of a distinct shape and size. here, we report a novel role for the drosophila klarsicht-anc-syne homology (kash) domain protein klarsicht (klar) in the regulation of microtubule (mt) stability and integrin receptor localization during salivary gland migration. in wild-type salivary glands, mts became progressively stabilized as gland migration progressed. in embryos specifically lacking the kas ... | 2015 | 26247519 |
| venus kinase receptors at the crossroads of insulin signaling: their role in reproduction for helminths and insects. | venus kinase receptors (vkrs) are invertebrate receptor tyrosine kinases (tks) first discovered in the human parasite schistosoma. they contain an extracellular venus flytrap module similar to the ligand-binding domain of g protein-coupled receptors of class c and an intracellular tk domain similar to that of insulin receptors. vkrs are present from cnidarians to echinoderms. they were shown to be activated by amino-acids, to induce insulin-like intracellular pathways, and to be highly expressed ... | 2015 | 26284029 |
| [influence of the sodium chloride content of larval resting places on the sensitivity of aedes aegypti to d.d.t., in relation to the development of anai papillae]. | 2015 | 13536763 | |
| larvicidal activity of few select indigenous plants of north east india against disease vector mosquitoes (diptera: culicidae). | mosquitoes are the vectors of several life threatening diseases like dengue, malaria, japanese encephalitis and lymphatic filariasis, which are widely present in the north-eastern states of india. investigations on five local plants of north-east india, selected on the basis of their use by indigenous communities as fish poison, were carried out to study their mosquito larvicidal potential against anopheles stephensi (malaria vector), stegomyia aegypti (dengue vector) and culex quinquefasciatus ... | 2015 | 25801251 |
| [action of development inhibitors on aedes aegypti l. mosquitoes and rhodnius prolixus stal. bugs. iv. the activity of precocenes]. | 2015 | 7024772 | |
| the influence of diet on the use of near-infrared spectroscopy to determine the age of female aedes aegypti mosquitoes. | interventions targeting adult mosquitoes are used to combat transmission of vector-borne diseases, including dengue. without available vaccines, targeting the primary vector, aedes aegypti, is essential to prevent transmission. older mosquitoes (≥ 7 days) are of greatest epidemiological significance due to the 7-day extrinsic incubation period of the virus. age-grading of female mosquitoes is necessary to identify post-intervention changes in mosquito population age structure. we developed model ... | 2015 | 25802436 |
| cd8+ t-cell responses in flavivirus-naive individuals following immunization with a live-attenuated tetravalent dengue vaccine candidate. | we are developing a live-attenuated tetravalent dengue vaccine (tdv) candidate based on an attenuated dengue 2 virus (tdv-2) and 3 chimeric viruses containing the premembrane and envelope genes of dengue viruses (denvs) -1, -3, and -4 expressed in the context of the attenuated tdv-2 genome (tdv-1, tdv-3, and tdv-4, respectively). in this study, we analyzed and characterized the cd8(+) t-cell response in flavivirus-naive human volunteers vaccinated with 2 doses of tdv 90 days apart via the subcut ... | 2015 | 25943203 |
| blood serum and bsa, but neither red blood cells nor hemoglobin can support vitellogenesis and egg production in the dengue vector aedes aegypti. | aedes aegypti is the major vector of dengue, yellow fever and chikungunya viruses that put millions of people in endemic countries at risk. mass rearing of this mosquito is crucial for strategies that use modified insects to reduce vector populations and transmission of pathogens, such as sterile insect technique or population replacement. a major problem for vector mosquito mass rearing is the requirement of vertebrate blood for egg production since it poses significant costs as well as potenti ... | 2015 | 26020000 |
| the rising importance of triatoma rubrofasciata. | the migration of invasive vector species has contributed to the worldwide extension of infectious diseases such as dengue (aedes aegypti) and chikungunya (aedes albopictus). it is probably a similar behaviour for certain vectors of chagas disease which allowed it to become a continental burden in latin america. one of them, triatoma rubrofasciata has also been spreading throughout the tropical and subtropical world. here, the recent and massive peridomestic presence of t. rubrofasciata in vietna ... | 2015 | 25807471 |
| evaluation of inapparent dengue infections during an outbreak in southern china. | few studies evaluating inapparent dengue virus (denv) infections have been conducted in china. in 2013, a large outbreak of denv occurred in the city of zhongshan, located in southern china, which provided an opportunity to assess the clinical spectrum of disease. during the outbreak, an investigation of 887 index case contacts was conducted to evaluate inapparent and symptomatic denv infections. post-outbreak, an additional 815 subjects from 4 towns with, and 350 subjects from 2 towns without r ... | 2015 | 25826297 |
| selective sweep analysis in the genomes of the 91-r and 91-c drosophila melanogaster strains reveals few of the 'usual suspects' in dichlorodiphenyltrichloroethane (ddt) resistance. | adaptation of insect phenotypes for survival after exposure to xenobiotics can result from selection at multiple loci with additive genetic effects. to the authors' knowledge, no selective sweep analysis has been performed to identify such loci in highly dichlorodiphenyltrichloroethane (ddt) resistant insects. here we compared a highly ddt resistant phenotype in the drosophila melanogaster (drosophila) 91-r strain to the ddt susceptible 91-c strain, both of common origin. whole genome re-sequenc ... | 2015 | 25826265 |
| two dopamine receptors play different roles in phase change of the migratory locust. | the migratory locust, locusta migratoria, shows remarkable phenotypic plasticity at behavioral, physiological, and morphological levels in response to fluctuation in population density. our previous studies demonstrated that dopamine (da) and the genes in the dopamine metabolic pathway mediate phase change in locusta. however, the functions of different dopamine receptors in modulating locust phase change have not been fully explored. in the present study, da concentration in the brain increased ... | 2015 | 25873872 |
| dengue in an area of the colombian caribbean. | in colombia, dengue is an endemic disease and the four serotypes have been reported. | 2015 | 26019378 |
| juvenile hormone-activated phospholipase c pathway enhances transcriptional activation by the methoprene-tolerant protein. | juvenile hormone (jh) is a key regulator of a wide diversity of developmental and physiological events in insects. although the intracellular jh receptor methoprene-tolerant protein (met) functions in the nucleus as a transcriptional activator for specific jh-regulated genes, some jh responses are mediated by signaling pathways that are initiated by proteins associated with plasma membrane. it is unknown whether the jh-regulated gene expression depends on the membrane-mediated signal transductio ... | 2015 | 25825754 |
| large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference. | the protein synthesis machineries of two distinct phyla of the animal kingdom, insects of arthropoda and mammals of chordata, have different preferences for how to best encode proteins. nevertheless, arboviruses (arthropod-borne viruses) are capable of infecting both mammals and insects just like arboviruses that use insect vectors to infect plants. these organisms have evolved carefully balanced genomes that can efficiently use the translational machineries of different phyla, even if the phyla ... | 2015 | 25825721 |
| invertebrate and vertebrate class iii myosins interact with morn repeat-containing adaptor proteins. | in drosophila photoreceptors, the ninac-encoded myosin iii is found in a complex with a small, morn-repeat containing, protein retinophilin (rtp). expression of these two proteins in other cell types showed ninac myosin iii behavior is altered by rtp. ninac deletion constructs were used to map the rtp binding site within the proximal tail domain of ninac. in vertebrates, the rtp ortholog is morn4. co-precipitation experiments demonstrated that human morn4 binds to human myosin iiia (myo3a). in c ... | 2015 | 25822849 |
| cloning and expressing a highly functional and substrate specific farnesoic acid o-methyltransferase from the asian citrus psyllid (diaphorina citri kuwayama). | the asian citrus psyllid, diaphorina citri, transmits a phloem-limited bacterium, candidatus 'liberibacter' asiaticus that causes citrus greening disease. because juvenile hormone (jh) plays an important role in adult and nymphal development, we studied the final steps in jh biosynthesis in d. citri. a putative jh acid methyltransferase ortholog gene (jmtd) and its cognate cdna were identified by searching d. citri genome database. expression analysis shows expression in all life stages. in adul ... | 2015 | 25893162 |