Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| dissemination of bla oxa-370 gene among several enterobacteriaceae species in brazil. | oxa-370 is a recently described oxa-48 variant that has only been described in a few enterobacter spp. and klebsiella pneumoniae isolates. the purpose of this study is to assess the prevalence of oxa-370-producing isolates in carbapenem-nonsusceptible enterobacteriaceae recovered from 28 hospitals from brazil. real-time pcr was used to determine the presence of bla ndm-1, bla kpc-2, bla vim-type, bla ges-type, bla oxa-48-like, and bla imp-type genes. a total of 4,451 enterobacteriaceae were scre ... | 2017 | 28555403 |
| imipenem-resistant gram-negative bacterial isolates carried by persons upon medical examination in korea. | carbapenem-resistant gram-negative bacteria (cr-gnb) have emerged and disseminated worldwide, become a great concern worldwide including korea. the prevalence of fecal carriage of imipenem-resistant gram-negative bacteria (ir-gnb) in persons in korea was investigated. stool samples were collected from 300 persons upon medical examination. samples were screened for ir-gnb by using macconkey agar with 2 μl/ml imipenem. species were identified by 16s rrna gene sequence analysis, and antimicrobial s ... | 2017 | 28721477 |
| assessment of facultative anaerobes from the root canals of deciduous molars: an in vivo study. | background. the current research aimed to assess the prevalence of facultative anaerobes isolated from the root canals of deciduous molars. methods. the present research enrolled 60 children in the 6‒9-year age group based on clinical and radiographic findings. under aseptic conditions, access cavities were prepared followed by collection of samples from infected root canals with the help of sterile paper points. the samples thus obtained were subjected for microbial assay. results. it was found ... | 2017 | 28748050 |
| spectrum and antibiotic resistance of uropathogens between 2004 and 2015 in a tertiary care hospital in hungary. | surveillance of the bacterial spectrum and antibiotic-resistance patterns of locally occurring uropathogens is essential to serve as a basis for empirical treatment of urinary tract infections (utis), as antibiotic-resistance rates may vary geographically with significant differences between countries and regions, and with time. | 2017 | 28621642 |
| collaborative research on puerperal infections in bangladesh. | bangladesh is considered as a high-risk country for emerging infectious diseases because of its high population density, poverty, and unhygienic conditions. although control efforts have primarily been focused on major infectious diseases such as diarrheal diseases, tuberculosis, malaria, and hiv infection, the prevalence and impact of many local or minor infectious diseases are still unclarified in this country. in this review, we present our recent experience and outcomes of collaborative rese ... | 2017 | 28552890 |
| influence of different wild-garlic (allium ursinum) extracts on the gastrointestinal system: spasmolytic, antimicrobial and antioxidant properties. | as there are no previous studies of the european wild-garlic (allium ursinum) effects on the gastrointestinal system, despite its traditional applications in gastrointestinal disorders' treatment and regular use in the human diet, we have quantified and compared spasmolytic, antimicrobial and antioxidant activities of its different leaf extracts. | 2017 | 28543032 |
| development of a panel of recombinase polymerase amplification assays for detection of common bacterial urinary tract infection pathogens. | to develop and evaluate the performance of a panel of isothermal real-time recombinase polymerase amplification (rpa) assays for detection of common bacterial urinary tract infection (uti) pathogens. | 2017 | 28510991 |
| antimicrobial resistance patterns in women with positive urine culture: does menopausal status make a significant difference? | aim. urinary tract infection (uti) is considered one of the most common bacterial infections in women. the aim of this study was to investigate the types of uropathogens present, as well as the degree of antimicrobial drug resistance seen among premenopausal (n = 2748) and postmenopausal (n = 1705) women with uncomplicated uti. methods. urinary samples (n = 4453) collected from women with uti were analyzed in terms of uropathogens present. these were considered as positive if bacterial growth wa ... | 2017 | 28497048 |
| recurrence of deep surgical site infection in cerebral palsy after spinal fusion is rare. | retrospective review of prospective registry. | 2017 | 28449964 |
| bacterial epidemiology and antimicrobial resistance profiles of urinary specimens of the elderly. | although urinary tract infections are the second leading cause of infections among patients aged above 65 years, data on bacterial epidemiology of urinary specimens in these patients is scarce. our aim was to describe the main bacterial species found at significant levels in urine specimens of the elderly and to determine their antimicrobial resistance profiles. | 2017 | 28408060 |
| prevalence study of plasmid-mediated ampc β-lactamases in enterobacteriaceae lacking inducible ampc from saudi hospitals. | enterobacteriaceae encoding plasmid-mediated ampc (pampc) β-lactamases confer resistance to the third generation cephalosporins. pampc association with extended spectrum β-lactamases (esbls), plasmid-mediated quinolone resistance (pmqr) and aminoglycoside modifying enzymes (ames) is well documented. there are limited data regarding the epidemiology and clinical significance of pampc in saudi arabia. this study aimed to determine the prevalence of pampc and its coexistence with esbls, pmqr and am ... | 2017 | 28820112 |
| evolving beta-lactamase epidemiology in enterobacteriaceae from italian nationwide surveillance, october 2013: kpc-carbapenemase spreading among outpatients. | extended-spectrum beta-lactamases (esbls), ampc-type beta-lactamases (acbls) and carbapenemases are among the most important resistance mechanisms in enterobacteriaceae. this study investigated the presence of these resistance mechanisms in consecutive non-replicate isolates of escherichia coli (n = 2,352), klebsiella pneumoniae (n = 697), and proteus mirabilis (n = 275) from an italian nationwide cross-sectional survey carried out in october 2013. overall, 15.3% of isolates were non-susceptible ... | 2017 | 28797330 |
| a novel type 1/2 hybrid incc plasmid carrying fifteen antimicrobial resistance genes recovered from proteus mirabilis in china. | incc plasmids are of great concern as vehicles of broad-spectrum cephalosporins and carbapenems resistance genes blacmy and blandm. the aim of this study was to sequence and characterize a multidrug resistance (mdr) incc plasmid (ppm14c18) recovered from proteus mirabilis. ppm14c18 was identified in a cmy-2-producing p. mirabilis isolate from chicken in china in 2014, and could be transferred to escherichia coli conferring an mdr phenotype. whole genome sequencing confirmed ppm14c18 was a novel ... | 2017 | 28757095 |
| propensity-matched analysis of the impact of extended-spectrum β-lactamase production on adults with community-onset escherichia coli, klebsiella species, and proteus mirabilis bacteremia. | the presence of extended-spectrum β-lactamase (esbl) in escherichia coli, klebsiella species, and proteus mirabilis (ekp) is of great microbiological and clinical importance. the study dealing with the direct impact of esbl producers on the outcome of patients with community-onset bacteremia is lacking. | 2017 | 28698042 |
| clinical benefits of antimicrobial de-escalation in adults with community-onset monomicrobial escherichia coli, klebsiella species and proteus mirabilis bacteremia. | the clinical benefits of an antimicrobial de-escalation strategy were compared with those of a no-switch strategy in bacteremic patients. adults with community-onset monomicrobial escherichia coli, klebsiella species and proteus mirabilis bacteremia treated empirically using broad-spectrum beta-lactams, including third-generation cephalosporins (gcs), fourth-gc or carbapenems, were treated definitively with first- or second-gcs (de-escalation group), the same regimens as empirical antibiotics (n ... | 2017 | 28694235 |
| expression, purification, and characterization of a membrane-bound d-amino acid dehydrogenase from proteus mirabilis jn458. | to characterize a novel membrane-bound d -amino acid dehydrogenase from proteus mirabilis jn458 (pmdad). | 2017 | 28676939 |
| effect of the 2014 clinical and laboratory standards institute urine-specific breakpoints on cefazolin susceptibility rates at a community teaching hospital. | enterobacteriaceae, which include escherichia coli, klebsiella pneumoniae, and proteus mirabilis, are identified as the infectious etiology in the majority of urinary tract infections (utis) in community hospitals across the united states. the minimum inhibitory concentration (mic) is a useful tool when choosing an appropriate antibacterial agent. recent changes to the 2014 clinical and laboratory standards institute (clsi) guidelines included reporting a urine-specific cefazolin breakpoint for ... | 2017 | 28558707 |
| development and characterization of a stable adhesive bond between a poly(dimethylsiloxane) catheter material and a bacterial biofilm resistant acrylate polymer coating. | catheter associated urinary tract infections are the most common health related infections worldwide, contributing significantly to patient morbidity and mortality and increased health care costs. to reduce the incidence of these infections, new materials that resist bacterial biofilm formation are needed. a composite catheter material, consisting of bulk poly(dimethylsiloxane) (pdms) coated with a novel bacterial biofilm resistant polyacrylate [ethylene glycol dicyclopentenyl ether acrylate (eg ... | 2017 | 28535686 |
| characterisation of a thiamine diphosphate-dependent alpha-keto acid decarboxylase from proteus mirabilis jn458. | alpha-keto acid decarboxylases can convert keto acids to their corresponding aldehydes, which are often volatile aroma compounds. the gene encoding α-keto acid decarboxylase in proteus mirabilis jn458 was cloned, and the enzyme overexpressed in escherichia coli bl21 (de3), purified in high yield, and characterised. the molecular weight is 62.291kda by maldi-tof ms, and optimum activity at ph 6.0 and 40-50°c. the enzyme is a typical decarboxylase, dependent on thiamine diphosphate and mg(2+) as c ... | 2017 | 28490063 |
| synergic bactericidal effects of reduced graphene oxide and silver nanoparticles against gram-positive and gram-negative bacteria. | reduced graphene oxide (rgo) is a promising antibacterial material, the efficacy of which can be further enhanced by the addition of silver nanoparticles (nag). in this study, the mechanisms of antibacterial activity of rgo-nag nanocomposite against several important human pathogenic multi-drug resistant bacteria, namely gram-positive coccal staphylococcus aureus and gram-negative rod-shaped escherichia coli and proteus mirabilis are investigated. at the same concentration (100 µg/ml), rgo-nag n ... | 2017 | 28484209 |
| assessment of urinary pharmacokinetics and pharmacodynamics of orbifloxacin in healthy dogs with ex vivo modelling. | the aim of this study was to investigate the urinary pharmacokinetics (pk) of orbifloxacin (obfx) administered at 5 mg kg-1 in six healthy dogs. a further aim was to use an ex vivo model to evaluate the urinary pk and pharmacodynamics (pd) of obfx to determine its urinary bactericidal titre (ubt), which represents the maximal dilution of urine allowing bactericidal activity. | 2017 | 28470147 |
| antibiofilm potential of synthetic 2-amino-5-chlorobenzophenone schiff bases and its confirmation through fluorescence microscopy. | antibacterial/antibiofilm potential of microwave-assisted synthetic thirty-three 2-amino-5-chloro benzophenone schiff bases have been carried out against four bacterial strains i.e. klebsiella pneumoniae, proteus mirabilis, staphylococcus aureus and streptococcus mutans. among them compounds 5, 6, 8, 9, 14, 16, 22, 24, 26, and 30-32 showed antibiofilm activities against isolates at less than 100 μg/ml concentrations. these compounds showed enhanced antibiofilm activity against s. aureus as compa ... | 2017 | 28755874 |
| antibiofilm potential of 16-oxo-cleroda-3, 13(14) e-diene-15 oic acid and its five new γ-amino γ-lactone derivatives against methicillin resistant staphylococcus aureus and streptococcus mutans. | the clerodane diterpenoids 16-oxo-cleroda-3, 13(14) e-diene-15 oic acid (1) and kolavenic acid (2) isolated from polyalthia longifolia var. pendula (linn.) were previously reported for their antimicrobial activity. thus present study was designed to investigate the biofilm inhibiting potential of these diterpenoids (1-2) and five new lactone derivatives (3-7) of 1 against methicillin resistant staphylococcus aureus (mrsa), streptococcus mutans, klebsiella pneumoniae and proteus mirabilis. compou ... | 2017 | 28692914 |
| formulation of carbapenems loaded gold nanoparticles to combat multi-antibiotic bacterial resistance: in vitro antibacterial study. | despite the fact that carbapenems (powerful β-lactams antibiotics) were able to fight serious infectious diseases, nowadays the spread of carbapenems-resistant bacteria is considered the main challenge in antibacterial therapy. in this study, we focused on evaluating the surface conjugation of carbapenems (imipenem and meropenem) with gold nanoparticles as a delivering strategy to specifically and safely maximize their therapeutic efficacy while destroying the developing resistance of the pathog ... | 2017 | 28411141 |
| lactococcus lactis as a safe and inexpensive source of bioactive silver composites. | this research develops a safe, inexpensive, and more accessible source for synthesis of silver nanoparticles. the bioactive silver composites synthesized by lactococcus lactis 56 ky484989 (lclb56-agcs) were characterized by various physico-chemical techniques and investigated for their antimicrobial activity and cytotoxicity. the average amount of nanoparticles was 0.363 ± 0.09 mg from 50 ml of culture medium. the synthesis efficiency varied from 71 to 85%. synthesized silver nanoparticles with ... | 2017 | 28842740 |
| oral immunisation with taishan pinus massoniana pollen polysaccharide adjuvant with recombinant lactococcus lactis-expressing proteus mirabilis ompa confers optimal protection in mice. | proteus mirabilis poses a critical burden on the breeding industry, but no efficient vaccine is available for animals. | 2017 | 28629671 |
| multidrug resistance salmonella genomic island 1 in a morganella morganii subsp. morganii human clinical isolate from france. | salmonella genomic island 1 (sgi1) is a multidrug resistance integrative mobilizable element that harbors a great diversity of antimicrobial resistance gene clusters described in numerous salmonella enterica serovars and also in proteus mirabilis. a serious threat to public health was revealed in the recent description in p. mirabilis of a sgi1-derivative multidrug resistance island named pgi1 (proteus genomic island 1) carrying extended-spectrum-β-lactamase (esbl) and metallo-β-lactamase resist ... | 2017 | 28435889 |
| a case of tetraplegia after proteus mirabilis infection. | 2017 | 28855782 | |
| postoperative nasal septal abscess following use of 2-octylcyanoacrylate and polydioxanone plate in open septorhinoplasty: a case series. | the employment of 2-octylcyanoacrylate adhesive (dermabond) to assist graft placement in open septorhinoplasty has been increasingly used to stabilize cartilage grafts. literature regarding this application has been mixed, with some showing the possibility of increased rates of inflammation, if not infection. we present an original comparative case series involving postoperative septal abscess formation adjacent to caudal strut grafting where both dermabond and an absorbable polydioxanone (pds) ... | 2017 | 28831833 |
| evaluation of biofilm-induced urinary infection stone formation in a novel laboratory model system. | infection stones comprise approximately 15% of all urinary tract stones and are induced by infection with urease-positive pathogens. the bacteria within the stone matrix present significant treatment impediments compared to metabolic kidney stones. while much is known about how urinary composition regulates metabolic stone formation, there is a general lack of knowledge around which urinary factors regulate the rate of infection stone formation. unfortunately, more in-depth research into infecti ... | 2017 | 28827106 |
| gc-ms analysis and gastroprotective evaluations of crude extracts, isolated saponins, and essential oil from polygonum hydropiper l. | peptic ulceration is among the most prevalent gastrointestinal disorders characterized by pepsin and gastric acid mediated mucosal damage, as result of imbalance between defensive and offensive processes. the main objective of the current study was to investigate the antiulcer potentials of polygonum hydropiper crude methanolic ectract (ph.cr) in aspirin induced ulcerogenesis using pylorus ligated rat model. in-vitro urease and proteus mirabilis inhibitory potentials were evaluated using standar ... | 2017 | 28824906 |
| camp receptor protein regulates mouse colonization, motility, fimbria-mediated adhesion, and stress tolerance in uropathogenic proteus mirabilis. | cyclic amp receptor protein (crp) is a major transcriptional regulator in bacteria. this study demonstrated that crp affects numerous virulence-related phenotypes, including colonization of mice, motility, fimbria-mediated adhesion, and glucose stress tolerance in uropathogenic proteus mirabilis. diabetic mice were more susceptible to kidney colonization by wild-type strain than nondiabetic mice, in which the crp mutant exhibited increased kidney colonization. loss of crp or addition of 10% gluc ... | 2017 | 28779108 |
| a shape-shifting redox foldase contributes to proteus mirabilis copper resistance. | copper resistance is a key virulence trait of the uropathogen proteus mirabilis. here we show that p. mirabilis scsc (pmscsc) contributes to this defence mechanism by enabling swarming in the presence of copper. we also demonstrate that pmscsc is a thioredoxin-like disulfide isomerase but, unlike other characterized proteins in this family, it is trimeric. pmscsc trimerization and its active site cysteine are required for wild-type swarming activity in the presence of copper. moreover, pmscsc ex ... | 2017 | 28722010 |
| septic arthritis of the pubis symphysis: clinical and therapeutic features. | septic arthritis of the pubis symphysis is rare and difficult to diagnose. the objective of our study was to describe the biological, clinical, radiological and therapeutic aspects of this disease. this is a retrospective study of 4 cases of septic arthritis of the pubic symphysis collected in the department of rheumatology and orthopaedics in sousse in tunisia over a period of 16 years (2000-2016). our population consists of 3 women and one men. the mean age was 47 years (18-83). clinical signs ... | 2017 | 28690730 |
| [proteus mirabilis septic arthritis]. | acute septic arthritis is rare. it is associated with poor prognosis in terms of mortality and morbidity. we report the case of a 61-year old patient with spontaneous proteus mirabilis septic arthritis. he suffered from complicated diabetes associated with positive blood cultures and synovial fluid cultures. patient's evolution was favorable thanks to early diagnosis and initiation of adequate antibiotic therapy. proteus mirabilis septic arthritis is rare. on that basis we conducted a literature ... | 2017 | 28674590 |
| genome-wide transposon mutagenesis of proteus mirabilis: essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements. | the gram-negative bacterium proteus mirabilis is a leading cause of catheter-associated urinary tract infections (cautis), which are often polymicrobial. numerous prior studies have uncovered virulence factors for p. mirabilis pathogenicity in a murine model of ascending uti, but little is known concerning pathogenesis during cauti or polymicrobial infection. in this study, we utilized five pools of 10,000 transposon mutants each and transposon insertion-site sequencing (tn-seq) to identify the ... | 2017 | 28614382 |
| genetic characteristic of class 1 integrons in proteus mirabilis isolates from urine samples. | proteus mirabilis is an opportunistic pathogen, commonly associated with complicated urinary tract infections (utis). utis caused by multidrug-resistant proteus mirabilis have increased worldwide. multidrug-resistance of gram-negative enteric bacteria is usually associated with class 1 integrons. | 2017 | 28612707 |
| identification and characterization of new members of the sxt/r391 family of integrative and conjugative elements (ices) in proteus mirabilis. | integrative and conjugative elements (ices) are self-transmissible chromosomal mobile elements that play significant roles in the dissemination of antimicrobial resistance genes. identification of the structures and functions of ices, particularly those in pathogens, improves understanding of the dissemination of antimicrobial resistance. this study identified new members of the sulfamethoxazole-trimethoprim (sxt)/r391 family of ices that could confer multi-drug resistance in the opportunistic p ... | 2017 | 28602701 |
| persistence of blacmy-2-producing proteus mirabilis in two gull colonies at a 1-year interval in southern france. | 2017 | 28572037 | |
| the link between proteus mirabilis, environmental factors and autoantibodies in rheumatoid arthritis. | rheumatoid arthritis (ra) is a relatively common and potentially disabling immune-mediated inflammatory systemic disease, predominantly affecting women and characterised by multiple small joint arthritis. extensive data supports the roles of genetic, environmental and microbial factors in the triggering and development of this disease. proteus mirabilis is considered as the main microbial culprit in the causation of ra. the evidence for the role of these microbes in ra and their links with commo ... | 2017 | 28516867 |
| phenotypic detection and antibiogram of β-lactamase-producing proteus species in a tertiary care hospital, india. | proteus species cause a variety of community- and hospital-acquired illnesses. synthesis of β-lactamases is the predominant mechanism for resistance to β-lactam antibiotics. among the β-lactamases, extended spectrum β-lactamases (esbls) and ampc β-lactamases are the most common. | 2017 | 28503342 |
| fourier transform infrared spectroscopy as a tool in analysis of proteus mirabilis endotoxins. | fourier transform infrared spectroscopy (ft-ir) was used to scan whole bacterial cells as well as lipopolysaccharides (lpss, endotoxins) isolated from them. proteus mirabilis cells, with chemically defined lpss, served as a model for the atr ft-ir method. the paper focuses on three steps of infrared spectroscopy: (1) sample preparation, (2) ir scanning, and (3) multivariate analysis of ir data (principal component analysis, pca). | 2017 | 28478562 |
| the impact of production of extended-spectrum β-lactamases on the 28-day mortality rate of patients with proteus mirabilis bacteremia in korea. | the incidence of proteus mirabilis antimicrobial resistance, especially that mediated by extended-spectrum β-lactamases (esbls), has increased. we investigated the impact of esbl production on the mortality of patients with p. mirabilis bacteremia in korea. | 2017 | 28468622 |
| genome sequence of a providencia stuartii strain isolated from luciliasericata salivary glands. | we present here the draft genome sequence of a providencia stuartii strain, derived from the salivary glands of larval lucilia sericata, a common blow fly important to forensic, medical, and veterinary science. the genome sequence will help dissect coinfections involving p. stuartii and proteus mirabilis, as well as blow fly-bacteria interactions. | 2017 | 28450516 |
| superficial swab versus deep-tissue biopsy for the microbiological diagnosis of local infection in advanced-stage pressure ulcers of spinal-cord-injured patients: a prospective study. | to assess the predictive value of superficial ulcer swab culture to make a microbiological diagnosis of deep wound infections in spinal cord injury (sci) patients with advanced-stage pressure ulcers. | 2017 | 28433727 |
| in vitro antibacterial activity of aqueous and ethanol extracts of aristolochia indica and toddalia asiatica against multidrug-resistant bacteria. | bacteria have developed multidrug resistance against available antimicrobial agents. infectious diseases caused by these multidrug-resistant bacteria are major causes of morbidity and mortality in human beings. synthetic drugs are expensive and inadequate for the treatment of diseases, causing side effects and ineffective against multidrug-resistant bacteria. the medicinal plants are promising to have effective antimicrobial property due to presence of phytochemical compounds like alkaloids, fla ... | 2017 | 26997710 |
| determination of antibacterial and technological properties of vaginal lactobacilli for their potential application in dairy products. | functional foods could differently affect human health in relation to the gender. recent studies have highlighted the anti-candida and anti-chlamydia activities of some lactobacillus strains isolated from the vagina of healthy women. considering these important beneficial activities on women's health, the preparation of functional food containing active vaginal lactobacilli can represent a great scientific challenge for the female gender. in this context, the aim of this work was to study some f ... | 2017 | 28223974 |
| in vitro activity of fosfomycin trometamol and other oral antibiotics against multi-drug-resistant uropathogens. | clinical midstream and urinary catheter isolates (n=106) of extended-spectrum β-lactamase (esbl)-positive escherichia coli, carbapenemase-producing klebsiella pneumoniae, proteus mirabilis and meticillin-resistant staphylococcus saprophyticus were tested against fosfomycin using the agar dilution method, the broth microdilution method and the gradient test described by the clinical and laboratory standards institute. nitrofurantoin, co-trimoxazole, amoxicillin/clavulanic acid, cefuroxime, levofl ... | 2017 | 28390962 |
| antimicrobial susceptibility monitoring of bacterial pathogens isolated from urinary tract infections in dogs and cats across europe: compath results. | compath is a pan-european antimicrobial surveillance program collecting bacterial pathogens from dogs and cats not recently exposed to antimicrobials. we present minimum inhibitory concentration data obtained using clinical and laboratory standards institute methodology for 616 urinary tract infection (uti) isolates collected between 2008 and 2010. in both dogs and cats, the most common pathogen was escherichia coli (59.8% and 46.7%, respectively). antimicrobial activity against e. coli in dogs ... | 2017 | 28384093 |
| [expression of proteus mirabilis polyphosphate kinase and preparation of its polyclonal antibodies]. | to express and purify polyphosphate kinase (ppk) from proteus mirabilis and prepare the polyclonal antibody against ppk. | 2017 | 28377345 |
| bioactivity of variant molecular weight chitosan against drug-resistant bacteria isolated from human wounds. | chitosan available from crab shells is usually of high molecular weight which may result in reduced efficiency for its antibacterial activity. one of the techniques for improving chitosan antibacterial efficiency is reducing its molecular weight. the irradiation of chitosan by gamma radiations is considered to be one of the most effective and widely used methods for improving its antibacterial activity. chitosan obtained from crab shells was irradiated with gamma radiations at different doses, a ... | 2017 | 28358617 |
| the effect of urinary catheters on microbial biofilms and catheter associated urinary tract infections. | the aims of this study were to determine relationship between biofilm producer microorganisms attached to urinary catheters (ucs) and urinary catheter-associated urinary tract infections (cautis), to determine the rate of cauti development and the relationship between cauti and catheterization period in catheterized patients. | 2017 | 28299769 |
| prevalence of extended-spectrum beta-lactamases-producing microorganisms in patients admitted at krrh, southwestern uganda. | the emergence of extended-spectrum beta-lactamase- (esbl-) producing pathogenic bacteria at kabale regional referral hospital (krrh), located in southwestern uganda, is of great concern: a phenomenon that worries clinicians and other healthcare workers due to the serious threat they pose to patients. this current study aimed at determining the phenotypic detection of esbl-producing strains of e. coli, klebsiella sp., and proteus sp. isolated from clinical specimens and their prevalence in patien ... | 2017 | 28270849 |
| chromosomal location of the fosa3 and blactx-m genes in proteus mirabilis and clonal spread of escherichia coli st117 carrying fosa3-positive inchi2/st3 or f2:a-:b- plasmids in a chicken farm. | the aim of this study was to investigate the spread and location of the fosa3 gene among enterobacteriaceae from diseased broiler chickens. twenty-nine escherichia coli and seven proteus mirabilis isolates recovered from one chicken farm were screened for the presence of plasmid-mediated fosfomycin resistance genes by pcr. the clonal relatedness of fosa3-positive isolates, the transferability and location of fosa3, and the genetic context of the fosa3 gene were determined. seven p. mirabilis iso ... | 2017 | 28238801 |
| antibacterial activities of manuka and honeydew honey-based membranes against bacteria that cause wound infections in animals. | in this study, membranes composed of honey (manuka or honeydew) and pectin were developed, and the iso 22196 method was used to evaluate their antibacterial activities against multidrug-resistant bacteria (i.e., staphylococcus pseudointermedius, escherichia coli, proteus mirabilis, pseudomonas aeruginosa) that cause wound infection in animals. the results demonstrated that both manuka and honeydew honey-based membranes had strong antibacterial activities against the strain of methicillin-resista ... | 2017 | 28174146 |
| antimicrobial activity and chemical composition of "kpètè-kpètè": a starter of benin traditional beer tchoukoutou. | the aim of this study was to investigate the antibacterial effect of the crude starter "kpètè-kpètè" and lactic acid bacteria used during the production of "tchoukoutou." to achieve this, a total of 11 lactic acid bacteria and 40 starter samples were collected from four communes. the samples were tested on 29 gram + and - strains by disk diffusion method. the minimum inhibitory and bactericidal concentrations of starter and lactic acid bacteria were determined by conventional methods. organic ac ... | 2017 | 28367445 |
| fosfomycin and comparator activity against select enterobacteriaceae, pseudomonas, and enterococcus urinary tract infection isolates from the united states in 2012. | fosfomycin is a broad-spectrum cell wall active agent that inhibits the mura enzyme involved in peptidoglycan synthesis and is fda-approved for treatment of uncomplicated urinary tract infections (utis) caused by escherichia coli and enterococcus faecalis in women. data regarding the susceptibility of recent uti isolates to fosfomycin are limited. | 2017 | 28285420 |
| the pathogenic potential of proteus mirabilis is enhanced by other uropathogens during polymicrobial urinary tract infection. | urinary catheter use is prevalent in health care settings, and polymicrobial colonization by urease-positive organisms, such as proteus mirabilis and providencia stuartii, commonly occurs with long-term catheterization. we previously demonstrated that coinfection with p. mirabilis and p. stuartii increased overall urease activity in vitro and disease severity in a model of urinary tract infection (uti). in this study, we expanded these findings to a murine model of catheter-associated uti (cauti ... | 2017 | 27895127 |
| method for bacterial growth and ammonia production and effect of inhibitory substances in disposable absorbent hygiene products. | the purpose of this study was to evaluate a pragmatic laboratory method to provide a technique for developing incontinence products better able to reduce malodor when used in the clinical setting. | 2017 | 27749743 |
| antimicrobial effectiveness of synthesized bioactive silver nanoparticles by the actinomycetes hgg16n strain. | biologically synthetized silver nanoparticles are promising antimicrobial agent. flow cytometry, well diffusion methods, colony-forming units (cfu) and spectroscopic approach are commonly used in antimicrobial study. the aims of this study were to provides information about effectiveness of bioagnps synthesized by actinomycetes hgg16n using fluorescence flow cytometry method as an alternative to the standard ones (well and disc diffusion method). | 2017 | 28056728 |
| aspergillus terreus brain abscess complicated by tension pneumocephalus in a patient with angiosarcoma. | background aspergillus terreus is an evolving opportunistic pathogen, and patients with a. terreus often have poor outcomes due to its intrinsic resistance to several systemic antifungal agents. here we present a unique case of intracranial abscesses of a. terreus in a patient with recurrent angiosarcoma, complicated by development of tension pneumocephalus. case report a 67-year old gentleman with history of scalp angiosarcoma with wide excision two years prior presented to the hospital for lef ... | 2017 | 28070116 |
| [community acquired urinary tract infections in older adults]. | background community acquired urinary tract infections (cauti) in adults are common ailments. older adults are prone to infectious diseases, diagnosis can be difficult, their etiologic and antimicrobial resistance are poorly known. objectives to evaluate the incidence discriminated by sex, symptoms, and to determine pathogens and their antimicrobial resistance rate. methods a retrospective, descriptive and comparative study. we analyze uricultures among 2013 in the hospital nacional de clinicas ... | 2017 | 28379126 |
| in vitro activity of imipenem against carbapenemase-positive enterobacteriaceae: smart global surveillance program 2008-2014. | the study for monitoring antimicrobial resistance trends (smart) global surveillance program collected 103,960 isolates of enterobacteriaceae from 2008 to 2014. from this isolate collection all ertapenem-non-susceptible isolates (mic, ≥1 μg/ml; n = 3,428) and 9,371 isolates of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, and proteus mirabilis with an ertapenem-susceptible extended-spectrum β-lactamase (esbl)-positive phenotype were assessed for the presence of common carbapenemas ... | 2017 | 28298454 |
| in vitro activity of ceftaroline and comparator agents against gram-positive and gram-negative clinical isolates from cancer patients. | bacterial infections are common in cancer patients. ceftaroline (cft) is a broad-spectrum cephalosporin with activity against most gram-positive organisms (gpos) and many gram-negative organisms. in this study, the in vitro activity of cft was compared with vancomycin (van), daptomycin (dap), linezolid (lzd), trimethoprim/sulphamethoxazole (sxt) and tigecycline (tig) against bacteria (predominantly blood culture isolates) isolated from cancer patients in 2014 and 2015. cft was active against met ... | 2017 | 28257904 |
| very high prevalence of extended-spectrum beta-lactamase-producing enterobacteriaceae in bacteriemic patients hospitalized in teaching hospitals in bamako, mali. | the worldwide dissemination of extended-spectrum beta-lactamase producing enterobacteriaceae, (esbl-e) and their subset producing carbapenemases (cpe), is alarming. limited data on the prevalence of such strains in infections from patients from sub-saharan africa are currently available. we determined, here, the prevalence of esbl-e/cpe in bacteriemic patients in two teaching hospitals from bamako (mali), which are at the top of the health care pyramid in the country. during one year, all entero ... | 2017 | 28245252 |
| molecular epidemiology of carbapenemase-producing enterobacteriaceae in a primary care hospital in japan, 2010-2013. | recently, carbapenemase-producing enterobacteriaceae (cpe) have been spreading worldwide and have become a threat in healthcare systems. we investigated the isolation frequency and molecular epidemiological characteristics of cpe isolated from clinical samples collected at a primary care hospital over the four years of 2010-2013 in japan. cpe were detected in 17 (0.34%) of 4875 isolates by the broth microdilution method, sodium mercaptoacetate inhibition test, and modified hodge test using merop ... | 2017 | 28161293 |
| potency and selectivity indices of acetone leaf extracts of nine selected south african trees against six opportunistic enterobacteriaceae isolates from commercial chicken eggs. | the rise in antimicrobial resistance in a plethora of nosocomial and opportunistic bacterial pathogens often isolated from commercial eggs, poses a serious public health concern. the existence of these contaminants may also serve as a drawback in the current efforts of improving the well-being of immunocompromised patients. the aim of this study was to determine the efficacy of plant extracts that had good activity on escherichia coli in previous word on pathogens isolated from eggs for possible ... | 2017 | 28148263 |
| in vitro activity of ceftazidime/avibactam against urinary isolates from patients in a phase 3 clinical trial programme for the treatment of complicated urinary tract infections. | to evaluate the in vitro activity of ceftazidime/avibactam relative to comparator agents against gram-negative isolates from a phase 3 clinical trial programme for complicated urinary tract infections (recapture). | 2017 | 28088768 |
| searching for a potential antibacterial lead structure against bacterial biofilms among new naphthoquinone compounds. | the aims of this study were to design, synthesize and to evaluate 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinones against gram-negative and gram-positive bacterial strains, including methicillin-resistant staphylococcus aureus (mrsa) and its biofilm, to probe for potential lead structures. | 2017 | 27930849 |
| serum bactericidal assay: new role in salmonella detection. | while inspecting animal feed for salmonella contamination, we routinely observed bacterial colonies on selective agars that were similar in appearance to those formed by salmonella. these were identified as citrobacter freundii, proteus mirabilis, and serratia fonticola using biochemical and serological techniques. because the presence of these bacterial species confounds identification of salmonella, we refer to them as "interference bacteria." polyvalent antisera against these interference bac ... | 2017 | 26822285 |
| the effect of sub-inhibitory concentrations of rifaximin on urease production and on other virulence factors expressed by klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa and staphylococcus aureus. | rifaximin, a topical derivative of rifampin, inhibited urease production and other virulence factors at sub-mic concentrations in strains involved in hepatic encephalopathy and the expression of methicillin resistance in staphylococcus aureus. in particular, urease production was affected in all proteus mirabilis and klebsiella pneumoniae strains as well as in all tested pseudomonas aeruginosa isolates. other exotoxins, synthesized by p. aeruginosa, such as protease, gelatinase, lipase, lecithin ... | 2017 | 27285830 |
| n-heterocyclic choline analogues based on 1,2,3,4-tetrahydro(iso)quinoline scaffold with anticancer and anti-infective dual action. | pharmacological effects of biologically active "small molecules" can be improved by their targeted modification, which affects drug delivery and interaction with tumor cells and microorganisms. we aimed to evaluate anticancer and antimicrobial activity of lipid-like choline derivatives modified via simultaneous introduction of tetrahydro(iso)quinoline based pharmacophore system at nitrogen atom and long chain alkyl substituent at oxygen atom. | 2017 | 28364698 |
| antimicrobial susceptibilities of aerobic and facultative gram-negative bacilli isolated from chinese patients with urinary tract infections between 2010 and 2014. | the objective of this study was to investigate the distribution and susceptibility of aerobic and facultative gram-negative bacilli isolated from chinese patients with utis collected within 48 h (community acquired, ca) or after 48 h (hospital acquired, ha) of hospital admission. | 2017 | 28264656 |
| potassium iodide potentiates broad-spectrum antimicrobial photodynamic inactivation using photofrin. | it is known that noncationic porphyrins such as photofrin (pf) are effective in mediating antimicrobial photodynamic inactivation (apdi) of gram-positive bacteria or fungi. however, the apdi activity of pf against gram-negative bacteria is accepted to be extremely low. here we report that the nontoxic inorganic salt potassium iodide (ki) at a concentration of 100 mm when added to microbial cells (10(8)/ml) + pf (10 μm hematoporphyrin equivalent) + 415 nm light (10 j/cm(2)) can eradicate (>6 log ... | 2017 | 28207234 |
| antimicrobial activity, ame resistance, and a-site binding studies of anthraquinone-neomycin conjugates. | the antibacterial effects of aminoglycosides are based on their association with the a-site of bacterial rrna and interference with the translational process in the bacterial cell, causing cell death. the clinical use of aminoglycosides is complicated by resistance and side effects, some of which arise from their interactions with the human mitochondrial 12s rrna and its deafness-associated mutations, c1494u and a1555g. we report a rapid assay that allows screening of aminoglycoside compounds to ... | 2017 | 28103015 |
| hatchery workers' igg antibody profiles to airborne bacteria. | occupational exposure to high concentrations of airborne bacteria in poultry production is related to an increased risk of respiratory disorders. however, etiology and in particular microorganisms' potential role in pathogenesis still needs to be elucidated. thus, detection of specific antibodies against occupational microbial antigens may lead to identification of potentially harmful species. for the purpose of igg titer determination, indirect immunofluorescence on various bacterial isolates f ... | 2017 | 28089178 |
| a study of pre-operative presence of micro-organisms in affected knee joints of rheumatoid arthritis patients who need total knee arthroplasty. | to evaluate, by way of intraoperative tissue culture and pathological study, the pre-operative presence of micro-organisms in knee joints of patients with rheumatoid arthritis (ra) who need total knee arthroplasty (tka). | 2017 | 27919672 |
| chromosomal amplification of the blaoxa-58 carbapenemase gene in a proteus mirabilis clinical isolate. | horizontal gene transfer may occur between distantly related bacteria, thus leading to genetic plasticity and in some cases to acquisition of novel resistance traits. proteus mirabilis is an enterobacterial species responsible for human infections that may express various acquired β-lactam resistance genes, including different classes of carbapenemase genes. here we report a proteus mirabilis clinical isolate (strain 1091) displaying resistance to penicillin, including temocillin, together with ... | 2017 | 27855079 |
| bacteriological assessment of pneumonia caused by gram-negative bacteria in patients hospitalized in intensive care unit. | the article presents the results of 11-year study (2005-2015) of gram-negative bacteria responsible for pneumonia in 2033 mechanically ventilated patients hospitalized in intensive care unit. of 8796 biological samples, consisting mainly of bronchial aspirate (97.9 %), 2056 bacterial strains were isolated and subjected to identification. vitek 2 was used to determine drug susceptibility (classified according to the eucast criteria). esbl, mbl and kpc-producing strains were identified by means of ... | 2017 | 27739023 |
| clonal transmission of gram-negative bacteria with carbapenemases ndm-1, vim-1, and oxa-23/72 in a bulgarian hospital. | we characterized 72 isolates with reduced susceptibility to carbapenems (50 acinetobacter spp., 13 proteus mirabilis, five escherichia coli, one morganella morganii, one enterobacter cloacae, one providencia rettgeri, and one pseudomonas aeruginosa) from a hospital in sofia, bulgaria. different β-lactamase genes were identified by polymerase chain reaction and sequencing. bacterial strain typing was performed by enzymatic macrorestriction and pulsed-field gel electrophoresis (pfge) typing as wel ... | 2017 | 27459019 |