Publications

TitleAbstractYear(sorted ascending)
Filter
PMID
Filter
swarming and pathogenicity of proteus mirabilis in the urinary tract.proteus mirabilis is best known for its pattern of swarming differentiation on agar plates, as well as for its association with the development of renal stones in patients with urinary tract infection. urease and flagella appear to contribute most significantly to virulence, with fimbriae playing a more subtle role, whereas hemolysin does not appear to contribute significantly to pathogenesis.19957551643
characteristics of ulcers of the small bowel induced by non-steroidal anti-inflammatory drugs in the rat: implications for clinical practice.small bowel ulcers were created in the rat after the oral administration of non-steroidal anti-inflammatory drugs (nsaids). of the six nsaids tested, indomethacin and diclofenac alone were associated with such damage which did not occur in a simple dose-related fashion. bacteria were observed by electron microscopy in an active state of division in the base of the ulcers. when grown aerobically these were shown to be strains of escherichia coli and proteus mirabilis. anatomically, nsaid-induced ...19957551656
the structure and serological specificity of proteus mirabilis o43 o antigen.on the basis of sugar analysis and nmr spectroscopy, including selective spin-decoupling, one-dimensional noe, two-dimensional homonuclear and 13c,1h-heteronuclear correlation spectroscopy, the following structure of the acidic o-specific polysaccharide of proteus mirabilis o43 was established: -->4)-alpha-d-galpa-(1-->3)-alpha-d-galpa-(1-->3)-alpha-d-gl cpnac-(1-->4)-alpha - d-glcp-(1-->, where gala is galacturonic acid and galp is galactopyranose. no serological cross-reactivity was observed b ...19957556207
buffering capacity and h+ membrane conductance of gram-negative bacteria.buffering capacity and membrane h+ conductance were examined in seven gram-negative species: aquaspirillum serpens, pseudomonas aeruginosa, alcaligenes faecalis, escherichia coli, salmonella typhimurium, proteus mirabilis and aeromonas hydrophila. all strains of enterobacteriaceae studied here showed a decrease in both parameters as the external ph increased, over the ph range studied. the other four species presented an increase in buffering capacity and membrane conductance to protons as the e ...19957557289
proteus mirabilis urease: operon fusion and linker insertion analysis of ure gene organization, regulation, and function.urease is an inducible virulence factor of uropathogenic proteus mirabilis. although eight contiguous genes necessary for urease activity have been cloned and sequenced, the transcriptional organization and regulation of specific genes within the proteus gene cluster has not been investigated in detail. the first gene, urer, is located 400 bp upstream and is oriented in the direction opposite the other seven genes, uredabcefg. the structural subunits of urease are encoded by ureabc. previously, ...19957559355
the effect of iontophoresis on bacterial growth in urine.to determine the effect of iontophoresis (electrical current for therapeutic purposes) on the growth of pathogenic bacteria in human urine.19957563389
[bacterial sacroileitis. clinical findinds and clinical course in 9 cases].since septic sacroileitis is one of the less frequent localizations among joint infections, we decided to review 9 cases in a retrospective study of 5 females and 4 males, aged between 22 and 60 years old. none had a clinically predisposing condition. the initiating factor was gynecologic-obstetric in 4 women, the irruption of the skin barrier in 3 cases and finally in one case the infection reached the joint through the psoas muscle. fever and lumbar pain were present in all cases and allowed d ...19957565046
molecular biology of microbial ureases.urease (urea amidohydrolase; ec 3.5.1.5) catalyzes the hydrolysis of urea to yield ammonia and carbamate. the latter compound spontaneously decomposes to yield another molecule of ammonia and carbonic acid. the urease phenotype is widely distributed across the bacterial kingdom, and the gene clusters encoding this enzyme have been cloned from numerous bacterial species. the complete nucleotide sequence, ranging from 5.15 to 6.45 kb, has been determined for five species including bacillus sp. str ...19957565414
[phenotypes of resistance to antibiotics of the most frequently isolated strains in five specialized hospital centers. multicenter study].antibiotic susceptibility of 948 bacterial strains isolated from varied samples essentially proceeding from urinary infections in five paris psychiatric hospitals was determined by disk diffusion method. e. coli, p. mirabilis, klebsiella spp., p. aeruginosa et s. aureus are the predominant bacteria. 40% of s. aureus are methicilline resistant. enterobacteriaceae are progressively becoming resistant to aminopenicillines, but remain sensitive to third generation cephalosporines. they are still sus ...19957567123
retrograde transmission of proteus mirabilis during platelet transfusion and the use of arbitrarily primed polymerase chain reaction for bacteria typing in suspected cases of transfusion transmission of infection.when bacteria are found, after a platelet transfusion, in the recipient's blood as well as in the platelet concentrate (pc), a causal relationship is normally suspected, with the pc as the causative agent. the other alternative, that the patient has bacteremia and contaminated the pc, is less well documented in the literature.19957570920
the structure of the o-specific polysaccharide chain of proteus penneri strain 42 lipopolysaccharide. 19957585721
cdna and genomic sequences for rat 8-oxo-dgtpase that prevents occurrence of spontaneous mutations due to oxidation of guanine nucleotides.the enzyme, 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase (8-oxo-dgtpase), is present in various organisms and plays an important role in control of spontaneous mutagenesis. this enzyme degrades 8-oxoguanine-containing deoxyribonucleoside triphosphate, a potentially mutagenic substrate for dna synthesis, to the corresponding monophosphate. to obtain appropriate probes for expression of the gene in various tissues and also to construct appropriate experimental models for carcinogenesis, we clone ...19957586133
the role of cefotaxime in the treatment of surgical infections.this study examines the role of cefotaxime in the treatment of both gram-negative and gram-positive surgical infections. a dose of 2 g of cefotaxime will sustain peripheral compartment concentrations of 2.6, 3.9, 1.6, and 0.7 micrograms/ml for 6, 8, 10 and 12 h, respectively. therefore, the proportion of pathogens with a minimal inhibitory concentration (mic) below the peripheral compartment cefotaxime concentrations was assessed as a measure of therapeutic potential. it was observed that bacter ...19957587036
the nuclear membrane-associated honeycomb structure of the unicellular organism amoeba proteus: on the search for homologies with the nuclear lamina of metazoa.in the protozoon amoeba proteus, a complex and highly organized structure with the morphology of a honeycomb is associated with the nucleoplasmic surface of the nuclear membrane. we have tested whether this structure exhibits similarity to the nuclear lamina of metazoic organisms. first, we have shown that the honeycomb layer is composed of 3 to 5 nm thick protein fibrils resistant to treatment with detergent, high salt, and digestion with nucleases, thus possessing properties typical for karyos ...19957588876
heavy metal effects on proteus mirabilis superoxide dismutase production.proteus mirabilis expressed three superoxide dismutase activities, which depended on the level of soluble iron and dioxygen in the culture medium. cadmium and lead decreased production of super oxide dismutase in liquid culture and on solid medium. a fourth super oxide dismutase activity appeared in extracts from cells grown in the presence of cadmium. these results support the idea of an interaction between toxic metal ions and putative iron- and redox-dependent regulatory systems.19957590184
microflora associated with percutaneous craniofacial implants used for the retention of facial prostheses: a pilot study.craniofacial implants have been used successfully for the retention of facial prostheses. however, complications occur that can lead to the loss of implant integration. one such complication is infection possibly resulting from crevicular microflora activity. as part of an ongoing study, samples from crevicular sites surrounding 17 craniofacial implants were collected and submitted for microbiological assay. the results demonstrated the presence of opportunistic pathogens in many sites regardles ...19957591002
characterization of the hemolytic activity of haemophilus ducreyi.h. ducreyi is the causative agent of chancroid, a genital ulcer disease most prevalent in developing countries. chancroid enhances the heterosexual transmission of human immunodeficiency virus and is identified in focal outbreaks in the united states, but little is known about its pathogenesis. we studied the hemolysin produced by h. ducreyi because this molecule might be an important virulence factor in the pathogenesis of chancroid. ten strains of h. ducreyi were tested on newly devised blood ...19957591078
effects of tazobactam on the frequency of the emergence of resistant strains from enterobacter cloacae, citrobacter freundii, and proteus vulgaris (beta-lactamase derepressed mutants).when enterobacter cloacae, citrobacter freundii, and proteus vulgaris were treated with piperacillin (pipc) in combination with tazobactam (taz), the in vitro frequency of emergence of resistant strains (beta-lactamase producing mutants) was lower than with pipc or ceftazidime (caz) treated bacteria. in a mouse intraperitoneal infection model caused by e. cloacae, beta-lactamase derepressed mutants were detected following therapy with pipc or caz, although no derepressed mutants were detected af ...19957592048
disposition of ornidazole and its metabolites during pregnancy.the disposition of ornidazole and its two major hydroxylated metabolites was studied in five pregnant women (gestational ages 25 5/7 to 38 4/7 weeks) with either chorioamnionitis or pyelonephritis treated with ceftriaxone 2 g, tobramycin 3 mg/kg body weight and ornidazole 1 g all administered once-daily. two series of blood samples were obtained, the first on the first day of treatment and the second at steady-state on day 5. local and systemic tolerability of ornidazole was excellent and patien ...19957592184
molecular analysis of a metalloprotease from proteus mirabilis.proteus mirabilis is known for its ability to differentiate from swimmer to swarmer cells, a process crucial for the pathogenesis of these bacteria during urinary tract infections. among the many virulence factors produced during swarmer cell differentiation is an extracellular metalloprotease. a cosmid containing a large fragment of p. mirabilis chromosomal dna was obtained by measuring protease expression in recombinant escherichia coli. the recombinant and native enzymes were purified to over ...19957592325
proteus mirabilis amino acid deaminase: cloning, nucleotide sequence, and characterization of aad.proteus, providencia, and morganella species produce deaminases that generate alpha-keto acids from amino acids. the alpha-keto acid products are detected by the formation of colored iron complexes, raising the possibility that the enzyme functions to secure iron for these species, which do not produce traditional siderophores. a gene encoding an amino acid deaminase of uropathogenic proteus mirabilis was identified by screening a genomic library hosted in escherichia coli dh5 alpha for amino ac ...19957592338
the regulatory c proteins from different restriction-modification systems can cross-complement.the bamhi restriction-modification system contains a third gene, bamhic, which positively regulates bamhir. similar small genes from other systems were tested in vivo for their ability to cross-complement. c.bamhi protein was identified, purified, and used to raise polyclonal antibodies. attempts to detect other c proteins in cell extracts by cross-reactivity with c.bamhi antibodies proved unsuccessful.19957592403
perspectives on craniofacial asymmetry. vi. the hamartoses.the hamartoses are a large group of disorders with autosomal dominant inheritance or sporadic occurrence. the genes responsible for some have been localized to specific chromosomes and in several instances, genetic heterogeneity has been established. thus neurofibromatosis and tuberous sclerosis are no longer single entities. for example, the gene for type i neurofibromatosis is on chromosome 17 and the gene for type ii is on chromosome 22. in this paper, genetic aspects of the hamartoses are up ...19957594750
inhibitory action of metabolites of pseudomonas aeruginosa against gram-negative bacteria.fifty clinical isolates of pseudomonas aeruginosa were tested for inhibition of growth of clinical isolates of escherichia coli, salmonella infantis, klebsiella pneumoniae and other gram-negative bacteria in the authors' laboratory. pseudomonas aeruginosa was strongly active against both e. coli and enterobacter cloacae, with 89.4% and 94.7% inhibition respectively, but weakly active against s. infantis, k. pneumoniae and proteus mirabilis with 56.3%, 48.8% and 23.8% inhibition, respectively. th ...19957594787
another look at the causes of the windblown hand. 19957595008
identification and characterization of a bacteroides gene, csuf, which encodes an outer membrane protein that is essential for growth on chondroitin sulfate.bacteroides thetaiotaomicron can utilize a variety of polysaccharides, including charged mucopolysaccharides such as chondroitin sulfate (cs) and hyaluronic acid (ha). since the enzymes (chondroitin lyases i and ii) that catalyze the first step in breakdown of cs and ha are located in the periplasm, we had proposed that the first step in utilization of these polysaccharides was binding to one or more outer membrane proteins followed by translocation into the periplasm, but no such outer membrane ...19957601836
plant bacterial spores, active systemically as a separate entity, play a significant role in human illnesses such as cancer, granulomas, aids, and milky white abdominal ascites that currently defies recognition.there is currently an unrecognized chapter in medical illnesses, occurring in living human beings, that defies recognition in explaining the diseases' origin and growth, and failing accurately to account for the pathophysiology involved. it is pertinent, therefore, to alert medical science, based upon facts as uncovered by my research studies (1-5), that plant bacterial spores can exist as a separate entity systemically. being totally devoid of the presence of their adult origin, they can surviv ...19957476596
microbiological quality of pharmaceutical raw materials.a total of 115 samples of pharmaceutical raw materials (excipients) were analysed: 36 lactose, 27 talc, 19 corn starch, 18 arabic gum, 8 gelatin, 3 gelatinized starch, 3 cellulose and one tragacanth gum. 69.9% of the samples showed less than 10(2) bacteria/g (mean = 23.2 cfu/g) and 95.2% less than 10(2) fungi/g (mean = 4.92 cfu/g). arabic and tragacanth gum were the most contaminated products by bacteria and fungi, respectively. pregelatinized starch, cellulose and lactose were the least contami ...19957480068
the specificity of the anti-proteus antibody response in tissue-typed rheumatoid arthritis (ra) patients from brest.anti-proteus mirabilis antibody titres were found to be elevated in 50 active tissue-typed french rheumatoid arthritis (ra) patients from brest when compared to 49 healthy french controls using enzyme-linked immunosorbent assay (elisa; p < 0.001) and indirect immunofluorescence assay (iifa; p < 0.001). however, there was no significant elevation in antibody titres against escherichia coli or salmonella typhimurium in the ra patients compared to the controls when measured by elisa. serum levels o ...19957481485
diagnosis and treatment of ear disease among children in the ellisras district. an outreach programme.audiologists and ent registrars examined 2,036 children aged 10 years or younger by means of pure-tone audiometry, tympanometry and otoscopic examinations. twenty per cent of these children had ear pathology and 7.5% had impaired hearing. forty-three pus swabs taken from patients with suppurative otitis media most often cultured proteus mirabilis and pseudomonas species. the prevalence of otitis media with effusion was twice as high in white children as in black children, resulting in a much hig ...19957482088
pharmacological proteus? 19957482982
bacterial causes of acute osteomyelitis in sickle cell anaemia: changing infection profile.the bacterial causes of osteomyelitis were reviewed on 25 patients with sickle cell anaemia using blood culture and direct wound swab. age range was 2 to 45 years with a median of 23 years. klebsiella species were cultured in 45% of the blood samples. staphylococcus aureus was responsible in 20%, salmonella species in 8% and streptococcus pyogenes was cultured in 4% of the samples. from direct wound swab culture, klebsiella was responsible for 36%, staphylococcus aureus 28% and coagulase negativ ...19958634234
studies on microbial aerobic flora of skin in leprosy patients.this study reports the isolation and identification of aerobic organisms from biopsies/slit-skin smears/scrapings from 129 leprosy patients and 50 healthy controls. these include 56 paucibacillary (pb) and 73 multibacillary (mb) cases. thirty-six isolates from the specimens from 21 patients and 15 healthy controls were grown. the non-mycobacterial isolates from clinically pb leprosy (tt/bt/i) patients were: (1) gram-positive cocci: staphylococcus aureus(1), staphylococcus albus(1); (b) gram-posi ...19958576610
intracranial complications of suppurative otitis media: 13 years' experience.among 24,321 patients with otitis media treated at the otolaryngology department of chiang mai university hospital from 1978 through 1990, 87 patients had 140 central nervous system complications (0.36%). multiple complications existed simultaneously in almost 45% of the patients. the group developing the complications were mainly in their second decade of life. meningitis occurred in 43 patients, brain abscess in 29, perisinus abscess in 23, lateral sinus thrombosis in 16, and extradural absces ...19958579165
[clinical and laboratory significance of inducible beta-lactamases].many species of bacteria have inducible expression of beta-lactamase and the enzyme production in these bacteria is normally held at a low level by a repressor mechanism, but in the presence of a beta-lactamase inducer this repression is lifted and enzyme production is greatly increased. inducible synthesis of beta-lactamase was first described for the gram-positive organism bacillus licheniformis. after that inducible expression of beta-lactamase was discovered in gram-negative bacteria like en ...19958643019
comparison of the efficacy and safety of isepamicin and amikacin in the treatment of skin and skin structure infections.two hundred and three patients with skin and skin structure infections were treated with isepamicin once daily or amikacin twice daily in an open, randomised, comparative multicentre trial. patients were randomised to treatment with isepamicin or amikacin in a 2:1 ratio. severe infections (63 patients) were treated with isepamicin 15 mg/kg once daily (n = 15) or amikacin 7.5 mg/kg twice daily (n - 18), less severe infections (140 patients) with isepamicin 8 mg/kg once daily (n = 93) or amikacin ...19958622105
the most frequently occurring aminoglycoside resistance mechanisms--combined results of surveys in eight regions of the world. the aminoglycoside resistance study groups.aminoglycoside-resistant isolates from different patients were collected in 149 hospitals in eight regions of the world. aminoglycoside resistance mechanisms were determined in 11,079 of these isolates by the correlation of resistance phenotypes to 12 aminoglycosides and dna hybridisation with up to 19 resistance genes. a very large diversity of different resistance mechanisms was found. for example, in escherichia-morganella-proteus-salmonella-shigella, at total of 53 different mechanisms was f ...19958622108
the changing nature of aminoglycoside resistance mechanisms and the role of isepamicin--a new broad-spectrum aminoglycoside. the aminoglycoside resistance study groups.aminoglycoside resistance mechanisms from recent studies were compared with those found in earlier studies in the usa and europe for three pathogen groups. among citrobacter-enterobacter-klebsiella, four single mechanisms (aac(3)-ii, aac(3)-i, ant(2")-i and aac(6')-i were found in all studies, but the most recent studies showed a significant increase in combinations of aac(6')-i with the other common mechanisms. since aac(6')-i confers resistance to tobramycin, netilmicin and amikacin, combinati ...19958622109
activity of biapenem (ljc 10627) against 51 imipenem-resistant bacteria and selection and characterisation of biapenem-resistant mutants.for wild-type bacteria the activity of biapenem was similar to that of imipenem, but for 51 imipenem-resistant strains meropenem was more active than either. when penicillin-binding protein 2a (pbp 2a) was expressed in staphylococcus aureus biapenem had reduced activity. mutant bacteria with decreased susceptibility to biapenem were selected in agar. most of the mutant gram negative bacteria were unstable and readily reverted to susceptible. the mutant proteus vulgaris and pseudomonas aeruginosa ...19958626267
[effects of the most frequently used solutions and ointments in routine surgical practice].the authors tested the effect of local antiseptics commonly used at the clinic of plastic and aesthetic surgery in brno on bacteria which most frequently infect extensive skin defects. the experiments were carried out in vitro and in vivo in a group of experimental animals. in vivo the effect on staphylococcus aureus and pseudomonas aeruginosa was investigated, in vitro also the effect on proteus mirabilis. the authors found that 0.1% persteril, peru balsam, and dermazine ung./lek co./exerted a ...19958658275
non-sporing anaerobes in certain surgical group of patients.the magnitude of non-sparing anaerobic (nsa) infections has been defined in the postoperative wounds on colorectum in children (57.1%), general surgery (0%), abdominoperineal and uterocervical operations (11-45%) in gynaecologic and obstetrical cases and perforative peritonitis (25.8-32.3%). children below the 6 months age group bear less risk of acquiring nsa infection. under certain situations, metronidazole combats nsa infections in a better way than other antibacterials. the bacteriology of ...19958648152
[sensitivity of bacteria of the genus proteus to antibiotics].antibiotic susceptibility of 481 cultures of the bacteria belonging to the genus proteus isolated within 1990-1994 from children with enterocolitis was studied. the study included 10 antibiotics. the efficacy of the antibiotic therapy in 388 children with the above disease was estimated. it was shown that the proteus isolates were most frequently susceptible to kanamycin, gentamicin and carbenicillin. when used clinically in the treatment of children with proteus enterocolitis, the antibiotics p ...19958651828
evaluation of cps id2 medium for diagnosis of urinary infections. 19958681994
proteus syndrome: a newly recognized hamartomatous syndrome with significant craniofacial dysmorphology.a new disorder describing multiple hamartomas distinct from neurofibromatosis and klippel-trenaunay-weber syndrome was first reported in 1979. it was named proteus syndrome after the greek god proteus, the polymorphous, who could change his shape at will to avoid capture. the clinical manifestations are extensive, including cranial exostoses; progressive enlargement, asymmetry and disfigurement of the skull; macrocephaly; exostoses of the ear canals, nasal bridge, and alveolar ridge; partial gig ...19958601022
intracapsular prostatic omentalization: a new technique for management of prostatic abscesses in dogs.twenty dogs with abscessation of the prostate gland were treated by celiotomy, drainage, and digital exploration of the gland through bilateral capsulectomy wounds. omentum was introduced through the capsulectomy wounds and packed into the abscess cavities around the prostatic urethra. most dogs were discharged from the hospital within 48 hours of the surgery. long-term resolution of the problem (no recurrence within 12 months) was achieved in 19 dogs. one dog had recurrent abscessation that was ...19958585146
plasma and urine disposition and dose proportionality of ceftiofur and metabolites in dogs after subcutaneous administration of ceftiofur sodium.nine male dogs (10.3-13.5 kg body weight) were randomly assigned to three groups of three dogs each and administered ceftiofur sodium subcutaneously as a single dose of 0.22, 2.2, or 4.4 mg ceftiofur free acid equivalents/kg body weight. plasma and urine samples were collected serially for 72 h and assayed for ceftiofur and metabolites (derivatized to desfuroylceftiofur acetamide) using high-performance liquid chromatography. urine concentrations remained above the mic90 for escherichia coli (4. ...19958587155
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1993). iii. secular changes in susceptibility].susceptibilities of enterococcus faecalis, staphylococcus aureus, citrobacter spp., enterobacter spp., escherichia coli, klebsiella spp., proteus mirabilis, pseudomonas aeruginosa and serratia spp. isolated from patients with urinary tract infections (utis) in 10 hospitals during june 1993 to may 1994 to various antimicrobial agents were compared with those in the same period of previous years according to a classification, uncomplicated utis, complicated utis without indwelling catheter, and co ...19958587162
hemifacial hyperplasia with meningeal involvement: a variant of proteus syndrome?we report on a sporadic case of hemifacial hamartomatous hyperplasia. the patient is male, and has sebaceous nevus-like skin change, subcutaneous lipomatous mass, cranial bone hyperplasia, and bony change of meninges. his lesion involves the anterior half of the face and cranial base, and, medially, is delimited by the midline. no case has been found identical to this in the literature, particularly with respect to the unusual meningeal lesion. however, without this meningeal lesion the rest of ...19958588580
turkey rhinotracheitis virus isolated from broiler chicken with swollen head syndrome in japan.turkey rhinotracheitis (trt) virus was first isolated from a commercial broiler chicken with swollen head syndrome (shs) in japan. at the same time, newcastle disease virus (ndv), infectious bronchitis virus (ibv), avian reovirus (arv), escherichia coli (e.coli), morganella morganii, and proteus mirabilis were also isolated from the same broiler chicken. the presence of antibodies to trt virus was confirmed in the sera of 34-day-old chickens of the flock with shs, however the antibodies to trt v ...19958593307
adult-onset langerhans cell histiocytosis associated with severe abscesses.we describe the case of an elderly lady who presented with a severe crusting skin eruption, mainly affecting the flexural areas and trunk. a diagnosis of langerhans cell histiocytosis was confirmed by electron microscopy, and her condition was eventually controlled with systemic prednisolone and short courses of etoposide. an unusual feature of this case was the development of severe pyogenic abscesses, particularly involving the cervical region. no underlying immunological defect has been found ...19958593721
a cell-surface polysaccharide that facilitates rapid population migration by differentiated swarm cells of proteus mirabilis.swarming by proteus mirabilis is characterized by cycles of rapid population migration across surfaces, following differentiation of typical vegetative rods into long, hyperflagellated, virulent swarm cells. a swarm-defective tnphoa insertion mutant was isolated that was not defective in cell motility, differentiation or control of the migration cycle, but was specifically impaired in the ability to undergo surface translocation as a multicellular mass. the mutation, previously shown to compromi ...19958594335
etiology and therapy of chronic suppurative otitis.infectious diseases of the ear are important in adults due to their incidence and relapses. we carried out a study of aerobic microorganisms on 251 otic exudates from patients diagnosed as having chronic suppurative otitis media without cholesteatoma (119), chronic suppurative otitis media with cholesteatoma (85) and chronic external otitis (47). the microorganisms predominantly isolated were, pseudomonas aeruginosa, staphylococcus aureus and other enterobacteriaceae. 86% of isolates were monomi ...19958596126
expression of flagella and motility by shigella.since the discovery of shigella as the aetiologic agent of acute dysentery almost 100 years ago, this organism has been described as a non-motile and nonflagellated organism that invades the human colonic mucosa. in this study, the production of flagella by prototypic strains of all four shigella species and, moreover, by fresh clinical isolates was demonstrated by electron microscopy. the flagellum of shigella (flash) is approximately 10 microns long and 12-14 nm in diameter and is typically se ...19958596461
imipenem resistance in clinical isolates of proteus mirabilis associated with alterations in penicillin-binding proteins.two strains of proteus mirabilis, ipr1 and ipr2, resistant to both imipenem and mecillinam, but susceptible to other beta-lactams were isolated from blood cultures of patients who had been treated with imipenem. strain ipr1 was isolated in the same sample as a p. mirabilis ips1 which was susceptible to imipenem and mecillinam. strains ipr1 and ipr2 did not produce a beta-lactamase and their outer membrane protein profiles were similar to those of ips1 and p. mirabilis atcc 29906. electrophoretic ...19958522463
in-vitro production of ethanol in urine by fermentation.driving while under the influence of alcohol (dui) can lead to serious injuries to the intoxicated driver and surrounding individuals, in addition to revocation or suspension of driving privileges. the accuracy and interpretation of the testing procedures may be compromised if an individual's urine contains sugar, and either bacteria or yeast. under these conditions, ethanol can be produced in vitro, producing a result that may be erroneously indicative of dui. in this study three yeast species ...19958522931
urinary tract infections and cholelithiasis in early childhood. 19958523217
development of mucosal humoral immune responses in germ-free (gf) mice. 19958525962
cleavage of igg and iga in vitro and in vivo by the urinary tract pathogen proteus mirabilis. 19958526000
differences in the motility of amoeba proteus isolated fragments are determined by f-actin arrangement and cell nucleus presence.isolated fragments produced by bisection of amoeba proteus differ by their position in the original cell and by the presence or absence of the cell nucleus. immediately after the operation, both types of anterior fragments preserve the former motory polarity, and do not interrupt locomotion. in the same time, all posterior fragments stop, round up and fail to react stimuli. in the second phase of experiment, these anterior fragments, which had no nucleus ceased to move, whereas the nucleated pos ...19958528194
in vitro activity of e-4868, a new fluoroquinolone with a 7-azetidin ring, compared with ciprofloxacin, ofloxacin and fleroxacin.e-4868, (-)-7[3-(r)-amino-2-(s)-methyl-1-azetidinyl]-1-(2,4- difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-3-quinolinecarboxylic acid, is a new fluoroquinolone with a 7-azetidin ring substituent. the in vitro activity against clinical isolates was compared with that of ciprofloxacin, ofloxacin and fleroxacin. in general, activity of e-4868 against aerobic and facultative anaerobic gram-negative bacilli was equal to or slightly less active than ciprofloxacin with the exception of morganella morganii ...19958529525
helicobacter pylori urease inhibition by rabeprazole, a proton pump inhibitor.we investigated the inhibitory effects of four gastric proton pump inhibitors (ppis): rabeprazole, a novel benzimidazole ppi, omeprazole, lansoprazole and ag-2000, on the urease activity of helicobacter pylori (h. pylori). their 50% inhibitory concentrations (i50s) were found to be 0.29, 5.4, 9.3 and 0.3 microm respectively. rabeprazole and omeprazole were also potent inhibitors of jack bean and proteus mirabilis cellular ureases. the thioether derivative of rabeprazole, one of its metabolites, ...19958535394
[determination of antibody kinetics in mediterranean spotted fever using the weil-felix agglutination test, complement fixation and indirect immunofluorescence].the kinetics of antibodies in human cases of mediterranean spotted fever was studied by applying weil-felix (wf) agglutination with proteus ox antigens, complement fixation (cf) and indirect immunofluorescence (if) tests with rickettsia conorri antigen to 46 sera from 21 patients. the kinetics of specific (cf and if) and nonspecific (wf) antibodies was similar. the percentage of the positive sera and geometric mean titers of antibodies reached the maximum after 14 days from the onset of illness.19958538356
[cystic fibrosis: a microbiological study over an 8-year period].to study the microbiology of cystic fibrosis in our hospital for the period from 1985 to 1992.19958542180
traumatic ear canal separations and para-aural abscessation in three dogs.three dogs were presented for para-aural abscessation. ear canal separations were suspected preoperatively, based on histories of trauma, physical examination findings of minimally inflamed external ear canals with abrupt endings, and radiographic evidence of discontinuity of the ear canals. concurrent otitis media, based on radiographic findings, was diagnosed in all three dogs. disruptions of the external ear canals were confirmed at surgery, and the dogs each responded to total ear canal abla ...19958542360
treatment of acute bacterial exacerbations of chronic obstructive pulmonary disease in hospitalised patients--a comparison of meropenem and imipenem/cilastatin. copd study group.meropenem and imipenem/cilastatin were compared in an open, randomised prospective multicentre study in the treatment of acute exacerbations of severe chronic obstructive pulmonary disease in hospitalised patients. one-hundred-and-seventy-three patients were enrolled; 164 were evaluable for clinical efficacy and 98 for bacteriological efficacy, with 144 pathogens isolated. the predominant pathogens were haemophilus influenzae (n = 30), streptococcus pneumoniae (18), staphylococcus aureus (12), p ...19958543488
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1990). i. susceptibility distribution].the frequencies of isolation and susceptibilities to antimicrobial agents were investigated on 848 bacterial strains isolated from patients with urinary tract infections in 10 hospitals during the period of june 1990 to may 1991. of the above total bacterial isolates, gram-positive bacteria accounted for 23.9% and a majority of them were enterococcus faecalis. gram-negative bacteria accounted for 76.1% and most of them were escherichia coli. 1. enterococcus faecalis: ampicillin (abpc), imipenem ...19958544334
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1990). iii. secular changes in susceptibility].susceptibilities of enterococcus faecalis, citrobacter spp., enterobacter spp., escherichia coli, klebsiella spp., proteus mirabilis, pseudomonas aeruginosa, serratia spp. isolated from patients with urinary tract infections (utis) in 10 hospitals during june 1990 to may 1991 to various antimicrobial agents were compared with those in the same period of previous years according to a classification, uncomplicated utis, complicated utis without indwelling catheter, and complicated utis with indwel ...19958544336
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1991). i. susceptibility distribution].the frequencies of isolation and susceptibilities to antimicrobial agents were investigated on 751 bacterial strains isolated from patients with urinary tract infections in 11 hospitals during the period of june 1991 to may 1992. of the above total bacterial isolates, gram-positive bacteria accounted for 28.6% and a majority of them were enterococcus faecalis. gram-negative bacteria accounted for 71.4% and most of them were escherichia coli. 1. enterococcus faecalis ampicillin (abpc), imipenem ( ...19958544337
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1991). iii. secular changes in susceptibility].susceptibilities of enterococcus faecalis, citrobacter spp., enterobacter spp., escherichia coli, klebsiella spp., proteus mirabilis, pseudomonas aeruginosa and serratia spp. isolated from patients with urinary tract infections (utis) in 11 hospitals during june 1991 to may 1992 to various antimicrobial agents were compared with those in the same period of previous years according to a classification, uncomplicated utis, complicated utis without indwelling catheter, and complicated utis with ind ...19958544339
inhibition of growth of proteus mirabilis and escherichia coli in urine in response to fasting and vegetarian diet.it has recently been shown that serum antibody levels against proteus mirabilis decreased in patients with rheumatoid arthritis who improved clinically during treatment with 7-10 days of fasting followed by a one-year vegetarian diet. as p. mirabilis is commonly implicated in urinary tract infections, this study was carried out to examine whether fasting and vegetarian diet may influence the growth of p. mirabilis and escherichia coli in urine. urine samples were collected from 22 patients who w ...19958546847
[evaluation of selective culture media for the isolation of salmonella from poultry].rambach agar, xylose-lysine-deoxycholate agar (xld) with different concentrations of tergitol 4 or 7 ethyl-2 methyl-4 undecanol hydrogen sulphate, sodium salt (xldt4), salmonella-shigella agar (ss) and bismuth sulfite agar according to wilson-blair (bs) were evaluated using salmonella spp. serovars and other bacterial species from the intestinal flora of poultry. growth of the most common salmonella serovars isolated from chickens in our country were evaluated using a viable counting technique o ...19958552759
[emphysematous pyelonephritis].the etiopathogenic and therapeutic aspects of emphysematous pyelonephritis, an uncommon disease entity, are discussed.19958554404
bacterial infection and semen characteristics in infertile men.semen samples of 190 men attending an andrology clinic were evaluated with bacteriological culture and categorized as negative (group i) and positive (group ii); the effect of bacteriospemia on semen characteristics was also analyzed. semen samples from both groups were simultaneously analyzed for routine parameters such as volume, sperm count, motility, viability and morphology. the semen culture was negative in 34% and positive in 66% of the samples. from 123 samples, 157 aerobes and 8 anaerob ...19958554430
tolerance to acid in ph 5.0-grown organisms of potentially pathogenic gram-negative bacteria.a wide range of potentially pathogenic species of gram-negative bacteria were far more resistant to extreme acidity (ph 2.0-3.5) when cultured at ph 5.0 (habituated to acid) than after ph 7.0 culture. the differences were particularly great for citrobacter spp., enterobacter spp., klebsiella spp. and for vibrio parahaemolyticus; substantial habituation was also observed for proteus mirabilis and aeromonas formicans but the effect was less marked for serratia marcescens and acinetobacter calcoace ...19958554762
a prevalence study of ear problems in school children in kiambu district, kenya, may 1992.information on the prevalence of hearing impairment and related ear pathologies in children in sub-saharan africa is scarce. a pilot study for a clinical trial of simple treatments for chronic suppurative otitis media (csom) in school children in kiambu district, kenya, provided information on the prevalence of hearing impairment and ear pathologies. five-thousand-three-hundred-sixty-eight children from 57 randomly chosen primary schools in kiambu district were examined. simple otoscopy was perf ...19958557476
an improved model for bacterial encrustation studies.a comparative evaluation of various biomaterials for their resistance to bacterial colonization and encrustation in infected urine is an important area in urological biomaterials research. this article describes an in vitro dynamic perfusion system that allows four reactors containing 24 1-in. catheter samples (6 per reactor) to be simultaneously perfused at a constant flow rate by synthetic urine. a common urease-producing urinary pathogen, proteus mirabilis, was maintained at a level of 10(6) ...19958557720
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1992). i. susceptibility distribution].the frequencies of isolation and susceptibilities to antimicrobial agents were investigated on 732 bacterial strains isolated from patients with urinary tract infections in 11 hospitals during the period of june 1992 to may 1993. of the above total bacterial isolates, gram-positive bacteria accounted for 35.4% and a majority of them were enterococcus faecalis. gram-negative bacteria accounted for 64.6% and most of them were escherichia coli. 1. enterococcus faecalis ampicillin (abpc), imipenem ( ...19958558754
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1992). iii. secular changes in susceptibility].susceptibilities of enterococcus faecalis, staphylococcus aureus, citrobacter spp., enterobacter spp., escherichia coli, klebsiella spp., proteus mirabilis, pseudomonas aeruginosa and serratia spp. isolated from patients with urinary tract infections (utis) in 11 hospitals during june 1992 to may 1993 to various antimicrobial agents were compared with those in the same period of previous years according to a classification, uncomplicated utis, complicated utis without indwelling catheter, and co ...19958558756
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1993). i. susceptibility distribution].the frequencies of isolation and susceptibilities to antimicrobial agents were investigated on 657 bacterial strains isolated from patients with urinary tract infections in 10 hospitals during the period of june 1993 to may 1994. of the above total bacterial isolates, gram-positive bacteria accounted for 28.3% and a majority of them were enterococcus faecalis. gram-negative bacteria accounted for 71.7% and most of them were escherichia coli. 1. enterococcus faecalis ampicillin (abpc), imipenem ( ...19958558757
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1993). ii. background of patients].clinical background was investigated on 734 bacterial strains isolated from patients with urinary tract infections (utis) in 10 hospitals during the period from june, 1993 to may, 1994. 1. distribution of sex, age and infections among over fifties males, the majority was taken by complicated urinary tract infections. among females, the uncomplicated urinary tract infections was most frequent without a relation of age. 2. distribution of sex, age and pathogens isolated from utis in uncomplicated ...19958558758
[gram-negative bacteria contaminating the process of producing lysine].the authors have isolated gram-negative bacteria of the enterobacteriaceae family from the culture liquid of industrial fermenters with low yield of lysine. most of them possessed the characters typical of klebsiella pneumoniae and escherichia coli, the rest were identified as the representatives of genera proteus, providencia, enterobacter, hafnia. strains of klebsiella pneumoniae, e.coli, proteus rettgeri manifested lysine-decarboxylase activity. the capacity of some strains to destruct lysine ...19958563944
[the efficacy of bacteriophage preparations in treating inflammatory urologic diseases].urinary infection is the most commonly encountered hospital infection. antibacterial therapy promotes selection and dissemination of polyresistant microorganism strains, development of intestinal dysbacteriosis, reduction of intestinal contamination resistance. clinical and bacteriological efficacy of urinary infection treatment with bacteriophage preparations (pyocyanic, proteus, staphylococcal, coliphage, combined pyobacteriophage) was studied. sensitivity of the infective agent phage isolated ...19958571474
exposure of the lateral enterocyte membrane by dissociation of calcium-dependent junctional complex augments endocytosis of enteric bacteria.intestinal bacterial translocation is facilitated in a variety of clinical conditions involving increased intestinal permeability, such as shock and trauma. because there is both in vivo and in vitro evidence that enteric bacteria can be internalized by intestinal epithelial cells, experiments were designed to test the effect of increased intestinal permeability on enterocyte endocytosis of enteric bacteria. mature, confluent cultures of ht-29 enterocytes were placed in a calcium-free solution f ...19958574756
[in vitro antibacterial activity of meropenem, a new carbapenem: european data].meropenem is a new dhp-i stable carbapenem with a very promising microbiological, pharmacokinetic and clinical profile. the antibacterial activity of this new agent has been assessed in vitro against 8741 aerobic and 854 anaerobic strains reflecting current incidence and epidemiology in italy, france, germany, spain, switzerland and united kingdom. comparator agents were imipenem, ceftriaxone, vancomycin, ciprofloxacin gentamicin and amikacin. the results of this study show that meropenem has a ...19958574928
analysis of bacteriuria in patients with burns.a detailed analysis of bacteriuria in 148 aged patients with burns was made for a period of 2 years (1991-92), in order to determine the incidence of the urine infections they sustained, the sources and mechanisms of the infections and the impact on the course and outcome of the primary disease. urine infection was found in 7.6 per cent (46 patients) of all patients treated for burns during the study period; 39.1 per cent were community acquired uroinfection (cau) and 60.9 per cent were hospital ...19957718115
bacterial entomopathogens from the drosophila paulistorum semispecies complex.bacteria which are infectious by inoculation in lepidoptera have been isolated and characterized from semispecies comprising the drosophila paulistorum complex. these microorganisms are pathogenic toward lepidopteran hosts such as heliothis virescens when introduced by injection of drosophila tissue extracts and have been given the trivial name dple (d. paulistorum lepidopteran entomopathogen). the dple from two of the semispecies, transitional and andean, were determined to be related to proteu ...19957722340
[what nobody thought possible--a "demobilization chain" gone astray. foreign body in the urinary bladder--a current differential diagnosis].intravesical foreign bodies should be considered in cases of unexplainable lower urinary tract symptoms or recurrent urinary tract infections with therapy-resistant microbes like proteus mirabilis and pseudomonas. usually these conditions are due to accidents in genitourinary surgery or instrumentation, but in our case occurred as a complication to an erotic procedure. this paper describes a case with a so-called "dimme-lenke", i.e. a chain used to count down days until demobilization from compu ...19957725283
cloning of multidrug resistance gene pqra from proteus vulgaris.the multiple antibiotic resistance gene pqra was cloned from the chromosomal dna of a clinical isolate of proteus vulgaris 881051 into escherichia coli ky2563. the mics of quinolones tetracycline, cephalosporin, and chloramphenicol for transformant strain dns7020 were from 8 to 32 times higher than those for the parent strain, ky2563. the level of expression of outer membrane protein f (ompf) by dns7020 was lower than that of ky2563 but not as low as that of an ompf-deficient control strain. the ...19957726514
cytotoxicity and antimicrobial activity of some naphthol derivatives.2-hydroxymethyl-1-naphthol diacetate (tac) and sixteen mannich base derivatives of naphthol were prepared and examined for cytotoxicity and antimicrobial activity. cytotoxicity was examined against four human carcinoma cell lines. several derivatives were effective at concentrations < 4 micrograms/ml. tac showed the highest cytotoxicity. inhibition of dna-, rna-, and protein synthesis by tac was also studied and discussed. tac also exhibits potent antimicrobial activity against enterobacter cloc ...19957726747
[the decontamination of microorganisms in potable water by using ultraviolet radiation].the inactivation of escherichia coli, streptococcus faecalis, proteus vulgaris, pseudomonas aeruginosa and bacillus subtilis by uv radiation in batch and flow-through systems and influence of different factors on inactivation have been studied. the necessary required disinfection doses were defined and compared with the data of other authors.19957728278
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1989). i. susceptibility distribution].the frequencies of isolation and susceptibilities to antimicrobial agents were investigated on 1,032 bacterial strains isolated from patients with urinary tract infections in 10 hospitals during the period of june 1989 to may 1990. of the above total bacterial isolates, gram-positive bacteria accounted for 30.8% and a majority of them were enterococcus faecalis. gram-negative bacteria accounted for 69.2% and most of them were escherichia coli. 1. enterococcus faecalis imipenem (ipm) showed the h ...19957474333
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1989). iii. secular changes in susceptibility].susceptibilities of citrobacter spp., enterobacter spp., escherichia coli, klebsiella spp., proteus mirabilis, pseudomonas aeruginosa, serratia spp. isolated from patients with urinary tract infections (utis) in 10 hospitals during june 1989 to may 1990 to various antimicrobial agents were compared with those in the same period of previous years according to a classification, uncomplicated utis, complicated utis without indwelling catheter, and complicated utis with indwelling catheter. as for c ...19957474335
randomized, double-blind comparison of single-dose regimens of rufloxacin and pefloxacin for acute uncomplicated cystitis in women. french multicenter urinary tract infection-rufloxacin group.in a double-blind, randomized, multicenter study, 463 adult women with symptomatic acute uncomplicated cystitis were treated orally with either a 400-mg single dose of rufloxacin (n = 226) or an 800-mg single dose of pefloxacin (n = 237). escherichia coli (78%) and proteus mirabilis (7%) were the most common isolates from 350 patients with significant pretreatment bacteriuria (uropathogens, > or = 10(5) cfu/ml). in the intention-to-treat analysis of patients with significant pretreatment bacteri ...19957695309
similar anti-proteus mirabilis titres in p1 positive and p1 negative individuals with rheumatoid arthritis. 19957668908
nucleotide sequences of two fimbrial major subunit genes, pmpa and ucaa, from canine-uropathogenic proteus mirabilis strains.proteus mirabilis strains were isolated from dogs with urinary tract infection (uti) and fimbriae were prepared from two strains. the n-terminal amino acid sequences of the major fimbrial subunits were determined and both sequences appeared identical to the n-terminal amino acid sequence of a urinary cell adhesin (uca) (wray, s. k., hull, s. i., cook, r. g., barrish, j. & hull, r. a., 1986, infect immun 54, 43-49). the genes of two different major fimbrial subunits were cloned using oligonucleot ...19957670636
[antibacterial effects of antiseptics in vitro and in an experiment in vivo].the effect of topical antiseptics routinely used in the department of plastic and aesthetic surgery was tested against bacteria commonly infecting burns and major skin defects. in vivo, the effect on staphylococcus aureus and pseudomonas aeruginosa was examined, in vitro also on proteus mirabilis. a very good effect on tested microorganisms was observed with 0.1% persteril, peruvian balsam and dermazin crm. (lek, ljubljana). gentian violet in a 0.5% concentration and 3% boric acid were not effec ...19957670805
postoperative pyomyositis following total hip replacement--a case report. 19957674212
[effectiveness of endoscope disinfection process].the effectiveness of flexible endoscopes disinfection was evaluated. since 1991 to 1994--157 inoculations were taken from endoscopic equipment--right after the examination and after their disinfection. following the endoscopes examinations were contaminated by microorganisms normally resident in the throat, respiratory and digestive tracts, but also with bacteria (acinetobacter, pseudomonas, proteus) which could be source of severe nosocomial infections. three times there was ps. aeruginosa on a ...19957676062
[the approval of an immunoenzyme test system based on the f(ab)2 fragments of staphylococcal antibodies for determining staphylococcal alpha-hemolysin].in the approbation of the enzyme-linked immunosorbent assay (elisa) system on the basis of f(ab)2 fragments of antistaphylococcal antibodies on 307 cultures of the representatives of the genera staphylococcus, pseudomonas and proteus high sensitivity, specificity and effectiveness of elisa for the quantitative and qualitative evaluation of the alpha-hemolytic activity of s.aureus were established. the elisa system has made it possible to additionally detect alpha-hemolysin in 62% of s.aureus str ...19957660713
bactericidal activity of normal human serum against morganella, proteus, and providencia strains.the susceptibility od proteus, providencia, and morganella strains to bactericidal action of human serum was examined. the percentage of survival was determined after one and three hours incubation with 50% human serum. the susceptible strains were treated by serum preparations with blocked classical or alternative complement activation pathways as well as with lysozyme removed. following mechanisms of the bactericidal action of serum were found: complement activated by the classical or alternat ...19957660859
Refresh
firstprev
...111112113114115116117118119120...
nextlast
Displaying items 11301 - 11400 of 15180