Publications

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[a study of the ecology of mosquito-borne arboviruses using sentinel animals in the volga delta]. 19714400989
inhibitors of haemaggregation in biological fluids. 19714325830
interferon and cell division. v. titration of the anticellular action of interferon preparations. 19714333094
distribution of arbovirus antigens in density gradients. 19715554483
[participation of birds in the water-nearwater complex of southeastern azerbaijan in the circulation of the west nile virus]. 19714255070
[detection of antibodies to a series of arboviruses of groups a, b and bunyamwera on the territory of the georgian ssr]. 19724260426
yellow fever vaccine. iv. reactogenicity and antibody response in volunteers inoculated with a vaccine free from contaminating avian leukosis viruses. 19724333781
yellow fever vaccine. 3. antibody response in monkeys inoculated with a vaccine free from contaminating avian leukosis viruses. 19724337545
isolation in portugal of west nile virus from anopheles maculipennis mosquitoes. 19724403183
arbovirus activity in israel. 19724404595
[change in the properties of antibodies in the primary immune response of rabbits to inoculation with west nile virus. i. characteristics of virus-neutralizing antibodies. correlation between specific and non-specific factors of immunity]. 19725028023
serological survey for arboviruses in igbo-ora, western nigeria. 19725038249
quantitative experiments on the vector capability of culex (culex) theileri theobald with west nile and sindbis viruses. 19725080426
the mechanism of cross-protection afforded by dengue virus against west nile virus in hamsters.the protection afforded by similar concentrations of different dengue virus serotypes against a subsequent challenge of west nile virus was studied in hamsters. the new guinea c strain of dengue 2 virus gave the best protection. it was found that the anamnestic neutralizing antibody response induced by the challenge west nile virus against west nile virus in hamsters, previously immunized with dengue 2 virus, might play a major role in the cross-protection observed in this system.19724509639
general discussion on the papers of session i. developments with hepatitis. 19724573940
[classification and identification of arboviruses]. 19724642703
the inhibition of lipid-containing viruses by an antilipemic agent. 19724660536
[serological research on detection of human infections with some group b arboviruses]. 19724669947
[change in antibody properties in the course of the immune response in rabbits to west nile virus inoculation. characteristics of the homo- and heterologous activity of immunoglobulins in the hemagglutination inhibition reaction]. 19724678190
[antibodies against arboviruses in starlings (sturnus vulgaris l.) in austria]. 19724145101
arboviruses in hungary. 19734145388
studies on antigenic peculiarities of west nile virus strains isolated in the u.s.s.r. by three serological tests. 19734148215
a complex natural focus of arboviruses on glinyanyi island, baku archipelago, azerbaidzhan s.s.r. 19734144280
[studies on the activity and ecology of arboviruses in turkey (author's transl)]. 19734148897
influence of incubation temperaure on interferon mechanism in cells of testudo graeca kidney. 19734148898
[survey with human sera from west cameroon (author's transl)]. 19734150072
field studies on the feeding habits of mosquitoes in the highveld region of south africa. 19734151015
soluble antigen of west nile virus. 19734131289
group b arbovirus structural and nonstructural antigens. 3. serological specificity of solubilized intracellular viral proteins.solubilized nonstructural antigen iii from saint louis encephalitis (sle)-japanese b encephalitis (jbe)-west nile (wn) and dengue-2 arbovirus-infected pig kidney cells was purified by employing brij-58 solubilization, organic solvent extraction, and column chromatography. diethylaminoethyl-cellulose column peak c eluate contained only intracellular viral envelope protein designated antigen i. antigen i of sle virus absorbed homologous neutralizing antibody; however, the intracellular nonstructur ...19734131773
studies of interferon production in aedes albopictus mosquito cells. 19734683227
aedes novalbopictus: establishment and characterization of larval cell lines. 19734691922
serum antibodies to b group arboviruses in apparently healthy persons of several districts in romania. 19734775621
serologic examination of some domestic animals from south moravia on the presence of antibodies to selected arboviruses of the a, b, california and bunyamwera groups. 19734777760
large scale irrigation and arbovirus epidemiology, kano plain, kenya. ii. preliminary serological survey. 19734779116
a serological survey on arbovirus antibodies in the sudan. 19734784057
[simple method for concentrating cultured antigens of the japanese encephalitis virus]. 19734786170
interferon production in arbovirus-infected cell cultures of tortoise (testudo graeca) kidney. 19734405393
persistence of tanapox in tana river valley.sera collected from inhabitants of the tana river valley in 1971 were examined for antibody to tanapox virus. neutralizing antibody was present in 16.3%. the levels of antibody and its presence in two children under the age of 10 years indicated that infection had been occurring in the area since the reported outbreak in 1962. a comparison of the incidence and distribution of antibodies in the same sera to west nile virus revealed marked similarities suggesting that tanapox, like west nile virus ...19734349335
[use of ultrasound for increasing the activity of arbovirus antigens in serological reactions in vitro]. 19734203622
[study of chronic forms of arbovirus infections in birds. 1. experiments with west nile, sindbis, bhandja and sicilian mosquito fever viruses]. 19734204261
viral isolates from livestock in northern nigeria: 1966-1970. 19734634068
[west nile fever with meningeal involvement]. 19734771807
isolation of viruses from wild mammals in west africa, 1966-1970. 19744210769
[role of birds in importing and preserving arboviruses (a review of the literature)]. 19744213786
serological survey for antibodies to arboviruses in the human population of portugal. 19744371206
cyclophosphamide-potentiated west nile viral encephalitis: relative influence of cellular and humoral factors. 19744372273
laboratory studies on the transmission of west nile virus by culex (culex) univittatus theobald; factors influencing the transmission rate. 19744423657
acute pancreatitis in west nile fever. 19744429184
cell lines from larvae of aedes (stegomyia) malayensis colless and aedes (s) pseudoscutellaris (theobald) and their infection with some arboviruses. 19744458148
genetically determined resistance to infection with group b arboviruses. i. distribution of the resistance gene among various mouse populations and characteristics of gene expression in vivo. 19744816304
genetically determined resistance to infection with group b arboviruses. ii. increased production of interfering particles in cell cultures from resistant mice. 19744593241
effects of interferon on antibody synthesis in vitro. 19744602660
[study of west nile virus antigens]. 19744141181
rats, flies and mosquitos of lebanon: pests, reservoirs and vectors of disease. 19744155006
haemagglutination-inhibiting antibodies to arboviruses in a human population in greece. 19744155197
[results of a study of west nile fever in the south of the european part of the ussr]. 19744454878
characterization of nigerian strains of west nile virus by plaque formation.seven strains of west nile virus isolated in nigeria were investigated for their ability to form plaques in monkey kidney cell monolayers. five strains antigenically related to one another produced plaques of about the same size 3 to 4 days after the addition of the overlay medium. the two other strains closely related to each other produced no plaques. their inability to produce plaques was regarded as a significant characteristic of the intratypic group to which the two strains belong.19751995
detection of west nile complement-fixing antigen in aedes albopictus cell cultures. 197552295
[determination of arbovirus group affiliation in the indirect hemagglutination reaction].a dry polyvalent erythrocyte immunoglobulin diagnostic preparation for arboviruses of group b may be prepared to be used in the indirect hemagglutination test. the preparation detects antigens of arboviruses of this group in the tissue culture fluid and in suckling mouse brain tissue treated with sucrose-acetone. the test with group b arbovirus antigens is inhibited specifically by the homologous polyvalent immune gamma globulin. inhibition of hemagglutination by species-specific immune globulin ...197554999
purification of togavirus haemagglutinins by chromatography on controlled pore glass.purified preparations of haemagglutinins from sindbis, west nile and tick-borne encephalitis (tbe) viruses could be obtained from infected mouse brains by alkaline extraction, precipitation with protamine and chromatography on polyethylene glycol-coated controlled pore glass with 242 a pore diameter.1975241241
use of duck embryo cell cultures for the study of arbovirus reproduction.duck embryo cell (dec) cultures were used for the study of arbovirus reproduction. high sensitivity of dec cultures to japanese encephalitis, west nile, tyuleniy, sakhalin and baku viruses was established. dec cultures are recommended for investigation of arbovirus reproduction.1975241248
an epidemiologic and serologic study of arboviruses in lake rudolf basin.an epidemiologic and serologic study of arboviruses was done in 1972 in the basin of lake rudolf. the main object of this study was to demarcate the southern limit of the yellow fever epidemic which occurred from 1959 to 1962 in southern sudan and ethiopia. other purposes were to contribute to the inventory of arboviruses and their distribution in this region. the ethnic groups were studied: the nyangatom and the dassanetch in ethiopia and the turkana in northern kenya. the results of tests on s ...1975242102
the enhancing effect of copper, nickel, and cobalt ions on plaque formation by semliki forest virus (sfv) in chicken embryo fibroblasts.in cultured chicken embryo fibroblasts treated with copper-(copper cation 10-minus 3.5-10-minus 5 m), nickel and cobalt salts an enhancement of the plating efficiency of semliki forest virus could be observed. this augmented plaque formation was most probably due to a higher adsorption rate of virions to the cell surface under the influence of the transition metal ions. the plating efficiency of west nile virus in chicken-embryo fibroblasts and, to a lesser degree, of poliovius type 1 and 2 in k ...1975167680
interferon induction and action in transformed poikilothermic cells.the production and effect of interferon in the virus-transformed cell line tgk1, originating from kidney cells of testudo gracea were studied and compared to those in the primary cell culture. west nile virus and newcastle disease virus were used as inducers. interferon production in tgk1 cells began 6 hr later than in the primary cell culture and reached the maximum 64 iu, 18 hr after virus inoculation. in the primary culture, interferon production increased till the 48th hr reaching a fourfold ...1975168742
an immunopathologic component in experimental togavirus encephalitis.the effects of immune manipulation upon survival and histopathology in two experimental group b togavirus encephalitides were studied in inbred mice. the median survival time 8 days after intracerebral injection of langat virus increased to 10 days with an immunosuppressive course of cyclophosphamide, with concomitant reduction in the inflammatory response. adoptive immunization with immune lymphoid cells or serum also tended to prolong langat virus survival while increasing inflammation. surviv ...1975171349
prevalence of antibodies to arboviruses in egypt. results of a serologic survey among 1,113 university students. 1975173201
serologic examination of birds from the area of southern moravia for the presence of antibodies against arboviruses of the groups alfa, flavo, bunyamwera supergroup, and the virus yaba 1-lednice 110. i. domestic fowls.196 geese, 141 ducks, and 100 hens from 9 localities of the south moravian region (district of breclav) were examined by means of the haemagglutination-inhibition test (hit) for the presence of antibodies against 12 arbovirus antigens of the groups alfavirus (western equine encephalitis (wee), eastern equine encephalitis (eee), semliki, sindbis, chikungunya, o'nyong-nyong), flavovirus (tick-borne encephalitis (tbe), dengue and west nile virus (wn), bunyamwera supergroup (tahna and beta calovo), ...1975175616
[fibrin removal from mouse immune ascitic fluids to arbovirus using beta-propiolactone].a modification of acid precipitation of fibrin in immune ascitic fluids (iaf) employing beta-propiolactone has been developed. the procedure removes fibrin completely without affecting the titres of specific antibody. this modification is not inferior to previously described methods for fibrin removal from iaf and has a number of advantages. in addition to removing fibrin from iaf, beta-propiolactone prevents possible virus contamination of iaf and sterilizes the preparation additionally.19751092073
virus infections in infant mice causing persistent impairment of turnover of brain catecholamines.newborn mice were inoculated with attenuated coxsackie type b4 virus. three-to-4-day old mice were infected with yellow fever virus vaccine. a number of mice survived the acute infections. some of these demonstrated residual neurological symptoms, some showed recovery from symptoms while others survived the infection without revealing symptoms of disease. determinations of dopamine, noradrenaline, 5-hydroxytryptamine, homovanillic acid and 5-hydroxyindoleacetic acid in the inoculated brains indi ...19751159458
structure and chemical-physical characteristics of lactate dehydrogenase-elevating virus and its rna.lactate dehydrogenase-elevating virus (ldv) was purified from culture fluid of infected primary cultures of various mouse tissues (peritoneal macrophage, bone marrow, spleen, and embryo) and from plasma of infected mice. electron microscopy of negatively stained virus and positively stained sections of ldv revealed spherical particles of uniform size with a diameter of about 55 nm, containing an electron-dense core with a diameter of about 30 nm. during sample preparation the envelope had a tend ...19751171266
infection of the mosquito aedes aegypti with infectious west nile virus-antibody complexes.aedes aegypti fed through chick skin membranes on west nile virus-homologous antiserum mixtures shown by an anti-globulin neutralization test to be highly infectious complexes (in terms of plaque formation in tissue culture) failed to become infected. control mosquitoes fed on west nile virus--normal rabbit serum mixtures containing similar or smaller amounts of infectious virus were shown to become infected. mosquitoes ingesting suspensions of west nile virus previously incubated with murray va ...19751080913
assay of togavirus haemagglutination-inhibition antibodies by the micro method: loss of information and its rectification.haemagglutination inhibition (hi) activity was assayed by the micro and macro methods in immune sera prepared against four togaviruses. hi titres were always 4 to 8 times lower by the micro method, and coincided with 4 to 8 times lower haemagglutinin titres in micro method assays. because of this phenomenon, positive sera with hi macro method titres lower than 1: 80 will be false negative for hi by the micro method when tests begin at a 1: 10 serum dilution. this was confirmed for a number of hu ...19761088357
the ornithodoros (alectorobius) capensis group (acarina: ixodoidea: argasidae) of the palearctic and oriental regions. o. (a.) maritimus: identity, marine bird hosts, virus infections, and distribution in western europe and northwestern africa.in 1967, vermeil and marguet described ornithodoros coniceps maritimus from larvae reared from larvae taken from marine birds on dumet island (atlantic ocean), basse bretagne, france. we collected o. (a.) coniceps canestrini, 1890, from the type locality (venice, italy) and determined that the taxons coniceps and maritimus each require full species status. we selected a lectotype and paralectotypes for the taxon maritimus from the original dumet island material. the larva of maritimus is redescr ...1976978368
infection of an aedes aegypti cell line with infectious arbovirus-antibody complexes.aedes aegypti cells exposed to infectious complexes of wn or yf virus and homologous antiserum produced lower yields of virus over a 10-day observation period than were produced by aedes aegypti cells treated with a comparable dose of virus mixed with non-immune serum. when ae. aegypti cells were infected with wn virus mixed with mve, nta, den-2 or yf antisera the virus yield over 10 days was lower than in cell cultures infected at similar titres with mixtures of wn virus with non-immune serum. ...1976982518
laboratory studies on the vector capability of aedes (neomelaniconion) unidentatus mcintosh and aedes (aedimorphus/ dentatus (theobald) with west nile and sindbis viruses.laboratory tests were made with aedes (neomelaniconion) unidentatus mcintosh and aedes (aedimorphus) dentatus (theobald) collected from the highveld region of the transvaal, south africa, to determine their ability of transmit west nile and sindbis viruses. viraemic hamsters or a viraemic chick were exposed to the mosquitoes as infective meals. infection of mosquitoes was determined by testing mosquitoes individually for the presence of virus 10-26 days later. transmission of virus, attempted be ...19761019752
solid-phase radioimmunoassay for antibodies to flavivirus structural and nonstructural proteins.a micro-solid-phase radioimmunoassay (spria) is described for quantitation of antibodies to purified flaviviruses as well as to the purified envelope glycoprotein and 80,000-molecular-weight viral nonstructural protein. sera from mice experimentally infected with saint louis encephalitis (sle) virus or from humans after a primary sle virus infection reacted more specifically with the major viral envelope protein in the spria test than with antigens conventionally used in the complement fixation ...19761270142
production of antibody in induced granulomas.a method of producing antibodies in artificially induced granulomas with various microbial antigens is examined.1976789397
[clinical and epidemiologic significance of arboviruses in central europe]. 1976794666
the susceptibility of isolated guts from various species of mosquito to some arboviruses.isolated guts cultured in vitro from aedes aeaegypti and ae. togoi were more susceptible to infection by sin, sf, chik and wn viruses than tissue similarly cultured from anopheles gambiae and an. stephensi. langat tp 64, a tick-borne virus, failed to infect any of the cultured mosquito tissues.1976178280
antigenic relationships among nigerian strains of west nile virus by complement fixation and agar gel precipitation techniques.using two serological techniques, eight nigerian west nile virus isolates were investigated to determine antigenic relationships among them, and to find out if these virus isolates were related to west nile virus strains from the different zoogeographic areas of the world. one virus differed significantly from the seven other strains and was later found to be a strain of usutu virus. the remaining strains were differentiated into two serological intratypic groups depending on their cross reactio ...197660810
interspecies interactions of arboviruses. i. competition phenomenon in mixed populations of japanese encephalitis and west nile viruses.two phenomena, competition and independent reproduction, were observed on co-cultivation of japanese encephalitis (je) and west nile (wn) viruses in permissive systems. competition occurred in populations propagated in mouse brains and led to elimination of je virus. only clones of wn virus were isolated from these populations at the 1st-3rd passage level. no competition was observed in mixed infection of primary syrian hamster kidney (shk) cell culturess the population had the combined immunolo ...197661719
replication of flaviviruses in mouse organ cultures [proceedings]. 197666024
interaction of mouse peritoneal macrophages with different arboviruses in vitro [proceedings]. 197666026
some properties of togavirus hemagglutinin studied with the aid of kaolin-adsorbed virus.acidification (at ph 5.75) of semliki forest virus and west nile virus suspensions completely eliminated their hemagglutinating activity within several minutes, but did not affect their infectivity or change their ability to absorb homologous hemagglutination-inhibition antibodies. in order to assay antibody absorption it was necessary to remove all of the immune complex from the reaction mixture, because the immune complex inhibited additional hemagglutinin. removal of the immune complex can be ...19769052
alterations in the developmental patterns of enzymes in chicken embryos infected with west nile virus. 197611747
epidemiologic study of arboviruses in the arba-minch district of ethiopia.a yellow fever outbreak occurred in 1966 in arba-minch district, east of abaya lake, in ethiopia. the present study was undertaken to assess the southern limits of that epidemic and to contribute to the inventory of arboviruses and potential vectors in that area. in the highlands 90 sera were collected, in the lowlands 140. with regard to group b the sera reacted only with yellow fever, wesselsbron and spondweni antigens. in the highlands 17.8%, in the lowlands 22.2%, were positive for group b. ...197613526
"karshi" virus, a new flavivirus (togaviridae) isolated from ornithodoros papillipes (birula, 1895) ticks in uzbek s.s.r.three identical strains of an arbovirus were isolated from 475 ornithodoros papillipes ticks collected in june, 1972, in burrows of the great gerbil (rhombomys opimus licht., 1882) in the environs of beshkent, karshinsk steppe, uzbek s.s.r. the isolate was found to range among flaviviruses. complement-fixation, agar diffusion precipitation and neutralization tests is tissue culture and mice indicated a one-way antigenic relationship between the isolate and west nile virus. however, the pattern o ...1976130853
antigenic analysis of nigerian strains of west nile virus by neutralization test.employing neutralization tests, eight nigerian strains of west nile virus were investigated to determine antigenic relationships among them. one virus strain differed so significantly from the others and was later found to be a strain of usutu virus. the other seven strains were differentiated into two serological intratypic groups dependent on their cross reactions with two strains which served as prototypes for each group. it was found that for epidemiological studies, screening of sera and se ...197616296127
effects of tilorone hydrochloride on experimental flavivirus infections in mice.the effect of tilorone hydrochloride on experimental infections of mice with west nile, langat and dengue type 2 viruses were studied. the drug significantly reduced the mortality after intraperitoneal inoculation of west nile virus, but failed to affect intracerebral infection with langat or dengue viruses. tilorone partially reversed cyclophosphan-enhanced mortality after extraneural inoculation of west nile and langat viruses. the possible modes of action of tilorone, interferon-inducing abil ...197717279
biological characteristic of nigerian strains of west nile virus in mice and cell cultures.the biological characteristic in mice and cell cultures of 7 strains of west nile (wn) virus isolated in nigeria were studied. the pattern of virus development in most organs of mice infected with two of the seven strains tested was identical, while it varied with the remaining five strains. all 7 strains of wn virus multiplied with a cytopathic effect (cpe) in the four cell cultures examined.197717286
interspecies interactions of arboviruses. ii. participation of the genomes of two flaviviruses, west nile and japanese encephalitis, in formation of a virus clone with dual antigenic determinants.a peculiar clone, 41/wn+je+, possessing antigenic determinants of a flaviviruses, west nile (wn) and japanese encphalitis (je), is described. the antigenic duality of this clone exceeded the cross reactions between wn and je viruses; either antiserum neutralized 104--105 pfu/ml of the virus. the property of antigenic duality was inherited in over 340 virus generations and retained upon propagation in selective cell systems and after recloning. the progeny of infectious rna consisted of 3 types o ...197766864
comparative serological studies on indian strains of west nile virus isolated from different sources. 197772730
affinity chromatographic analysis of murine interferons induced by viruses and by t and b cell stimulants.murine interferons induced by viruses and by non-viral substances such as lectins, tilorone, lipopolysaccharide and brucella have been analysed by affinity chromatography on a column of sepharose coupled to antiviral interferon antibodies. the results reported here suggest that virus and b-cell stimulants induced interferons which are antigenically related and that t cell-dependent mitogens induce and "interferon like" molecule which appears to be antigenically and physiocochemically different.1977301376
increase in lipid fluidity of cellular membranes induced by adsorption of rna and dna virions.changes in the dynamic behavior of membrane lipids of mammalian cells induced by adsorption of animal viruses were quantitatively monitored by fluorescence polarization analysis with the aid of the fluorescent probe 1,6-diphenyl 1,3,5-hexatriene embedded in the surface membrane lipid core of intact cells. adsorption of encephalomyocarditis, west nile, and polyoma viruses to hamster (baby hamster kidney) and mouse (3t3) cells is accompanied by a rapid and significant increase in the degree of flu ...1977194057
reactions of egyptian human and rodent sera to langat virus antigens. 1977198509
studies on the occurrence and distribution of hi antibodies against some arboviruses in the serum of domestic mammals in puglia.the virological and serological studies previously carried out on arboviruses in italy are reviewed. the presence of antibodies to 11 arboviruses was investigated in the serum of various domestic animals (100 horses, 107 pigs, 102 sheep, 205 goats, 100 cattle and 200 dogs) from some areas of puglia. the techniques are described. the results, given in tables and discussed in detail, support the hypothesis that in this region also there are arboviruses circulating, particularly those of group b.1977201546
arboviruses in birds captured in slovakia.virus neutralizing (vn) antibodies against sindbis, tick-borne encephalitis (tbe), west nile (wn), tahyna and calovo viruses were found in birds captured in slovakia. in parallel, sindbis, tbe and wn viruses were isolated from the blood, brain and liver of migrating birds.1977203628
picorna- and togavirus infection of cells detected by gas chromatography.viral infection of cells causes chemical and metabolic changes, which can be detected by gas chromatography (gc) of ether extracts of supernatant fluids and cell homogenates before any significant damage to the cells is observable microscopically. the characteristic and specific gc patterns obtained from bhk-21 and vero cell cultures infected with encephalomyocarditis, polio, echoviruses, and a togavirus make it possible to distinguish between these infecting viruses. the appearance of 1 or 2 co ...1977204744
role of extracellular virus on the maintenance of the persistent infection induced in aedes albopictus (mosquito) cells by sindbis virus.sindbis virus infection of cultured mosquito cells was found to have no effect on the growth of these cells; instead, a persistent infection of the culture followed an initial acute phase of rapid virus synthesis. nearly all of the cells in the acute stage of infection were found to actively release virus in an infectious-center assay and to contain significant amounts of virus antigen as determined by immunofluorescence. cells in the persistent phase of infection released few virions into the m ...1977561193
epidemic outbreak caused by west nile virus in the crew of a romanian cargo ship passing the suez canal and the red sea on route to yokohama. 1977602018
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