Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| host failure in treatment of malaria with sulfalene and pyrimethamine. | an individual infected with a multidrug-resistant strain of plasmodium falciparum failed to respond to treatment with sulfalene and pyrimethamine. subinoculation studies showed that parasite resistance to the drug combination was not present. plasma levels of sulfalene and pyrimethamine in this individual were similar to those of three individuals, subinoculated from him, who were cured by the drug combination. erythrocyte levels of sulfalene in this individual were similar to those in an indivi ... | 1975 | 1090224 |
| letter: unexplained fever. | 1975 | 1090330 | |
| the prevalence and relationships of malaria, anemia, and malnutrition in a coastal area of el salvador. | to study the relationships between malaria, anemia and malnutrition, 853 school-age children from a high malaria incidence area and an adjacent low incidence area were surveyed in september 1972. for the high incidence area the malaria slide positivity rate was 3.5%, spleen rate 7.6% and malaria (indirect fluorescent antibody) serology positivity 24.7%. contrasted to this, no positive slides, only 3 palpable spleens and a 3.4% serology positivity rate were found for the low incidence area. twent ... | 1975 | 1091165 |
| a prospective study of the effects of ultralow volume (ulv) aerial application of malathion on epidemic plasmodium falciparum malaria. i. study design and perspective. | a large-scale prospective study was designed to test the effects of aerial ultralow volume (ulv) application of malathion on epidemic plasmodium falciparum malaria. the study was conducted during 1972 to 1973, in the miragoane valley of haiti, an area having annual anticipated outbreaks of malaria, which allowed prospective assessment. spraying of malathion at a dosage of 4.5 fluid ounces per acre reduced populations of adult anopheles albimanus to less than 1% of prespray levels and interrupted ... | 1975 | 1091167 |
| a prospective study of the effects of ultralow volume (ulv) aerial application of malathion on epidemic plasmodium falciparum malaria. ii. entomologic and operational aspects. | in a large-scale study in the miragoane valley of haiti, designed to test the effects of aerial ultralow volume (ulv) malathion on epidemic plasmodium falciparum malaria, spray operations resulted in an immediate and sharp decline in numbers of the vector, anopheles albimanus. the adult population of this mosquito remained at less than 1% of previous levels until several weeks after a 50-day spray period (27 october-16 december 1972) during which six cycles were completed. the study area offered ... | 1975 | 1091168 |
| a prospective study of the effects of ultralow volume (ulv) aerial application of malathion on epidemic plasmodium falciparum malaria. iii. ecologic aspects. | the effects of aerial ultralow volume (ulv) malathion on selected species of nontarget animals in haiti are reported. mortality of certain groups of insects such as bees, flies, beetles, and butterflies was observed immediately following spray application. minor fish mortality occurred only in shallow water exposed to direct spray. the brain acetylcholine esterase levels of living fish, tree lizards, birds and bats collected from treated areas were not significantly reduced. no ill or dead anima ... | 1975 | 1091169 |
| a prospective study of the effects of ultralow volume (ulv) aerial application of malathion on epidemic plasmodium falciparum malaria. iv. epidemiologic aspects. | in the miragoane valley of haiti a consistent pattern in the incidence of plasmodium falciparum malaria over a 10-year period made it possible to predict an annual outbreak and perform a prospective study to test the effects of aerial ultralow volume (ulv) malathion on epidemic levels of this disease. at the end of october 1972, after epidemic levels (100 cases/month/10,000 population) had been reached, spray operations were begun. the first spray cycle produced a sharp and immediate drop in pop ... | 1975 | 1091170 |
| antimalarial effects of clindamycin in man. | clindamycin 450 mg every 8 hours for 3 days cured three non-immune patients of falciparum malaria, although the response was slow. the addition of quinine to this regimen provided an accelerated response and cured 3 of 5 other patients. single doses of clindamycin given daily for 3 days, with or without quinine, cured 1 of 3 patients. gastric intolerance to the drugs, probably accentuated by the clinical condition, was pronounced in some cases, the course of treatment being interrupted in three ... | 1975 | 1091172 |
| letter: prevention of chloroquine-resistant falciparum malaria. | 1975 | 1091190 | |
| [demonstration of chloroquine diphosphate resistance in plasmodium falciparum strains naturally infecting man in an area of the bolivar state, venezuela]. | 1975 | 1091958 | |
| suppression of malaria with monthly administration of combined sulphadoxine and pyrimethamine. | a trial of suppression of malaria by administration of combined sulphadoxine-pyrimethamine tablets every 28 days was undertaken in west malaysia during 1972. one thousand subjects were followed over a 10-month period, including control groups on placebo and on weekly chloroquine. subjects were examined monthly for parasitaemia, drug reactions, leucopenia, teratogenicity and haemolysis among the subjects deficient in glucose-6-phosphate dehydrogenase. rates of new infections in the placebo group ... | 1975 | 1092276 |
| chloroquine-resistant falciparum malaria from west irian and east kalimantan. | 1975 | 1092277 | |
| new serological test for malaria antibodies. | in an enzyme-linked immunosorbent assay test for malaria antibodies, antibodies to plasmodium vivax and p. falciparum in man are detected using a crude antigen prepared from the simian malaria parasite p. knowlesi. the test may be suitable for epidemiological studies. | 1975 | 1092412 |
| effects of red cell extract on in vitro growth and multiplication of malarial parasites. | an extract of red blood cells was prepared from monkey blood. red cell extract (rce) of aotus monkeys was beneficial for the in-vitro cultivation of 2 strains of p. falciparum. the active material(s) in aotus rce was not sedimented by centrifugation at 34,800 g for 1 hr. rhesus monkey rce improved the growth of p. knowlesi for in-vitro cultivation through 4 schizogonous cycles (88 hr). | 1975 | 1092828 |
| a model of how the sickle-cell gene produces malaria resistance. | 1975 | 1092922 | |
| falciparum malaria semi-resistant to clindamycin. | clindamycin, a semi-synthetic antibiotic of the lincomycin family, at a dose of 450 mg eight-hourly for three days in adults cured five out of 10 patients moderately ill with chloroquine-resistant falciparum malaria. combination therapy with full-dose quinine and clindamycin for three days cured all four patients so treated who were followed up, and with half dosage three out of five patients were cured. both combinations, however, caused upper gastrointestinal toxicity and appeared to potentiat ... | 1975 | 1093609 |
| falciparum malaria cured by quinine followed by sulfadoxine-pyrimethamine. | quinine (at least four doses given at intervals of eight to 12 hours) followed by a single dose of sulfadoxine-pyrimethamine (fansidar) is the most effective treatment of chloroquine-resistant falciparum malaria. this regimen cured 96% of patients (302 out of 314) with an average initial parasite count of 90 x 10-9/1. | 1975 | 1093610 |
| letter: treatment of falciparum malaria. | 1975 | 1093620 | |
| sulfadoxine and pyrimethamine in the treatment of falciparum malaria in vietnam. | 1975 | 1094249 | |
| circadian and other rhythms of parasites. | 1975 | 1094812 | |
| "topical nephropathy" and "tropical extramembranous glomerulonephritis" of unknown aetiology in senegal. | a study of renal biopsy specimens obtained in senegal from 24 children and six adults with nephrotic syndrome showed two unusual varieties of nephropathy--namely, an extramembranous glomerulonephritis associated with hypocomplementaemia (four cases), a combination previously described only in systemic lupus erythematosus, and a "tropical nephropathy" (16 cases). the latter, though lacking the diffuse glomerular deposits of immunoglobulin described in quartan malarial nephropathy (q.m.n.), showed ... | 1975 | 1095112 |
| cerebral malaria. | cerebral malaria is an acute diffuse encephalopathy associated only with plasmodium falciparum. it is probably a consequence of the rapid proliferation of the parasites in the body of man in relation to red cell invasion, and results in stagnation of blood flow in cerebralcapillaries with thromobotic occlusion of large numbers of cerebral capillaries. the subsequent cerebral pathology is cerebral infarction with haemorrhage and cerebral oedema. the wide prevalence of p. falciparum in highly ende ... | 1975 | 1095294 |
| chloroquine resistant malaria in west malaysia. | chloroquine resistance is a well established entity in south east asia, and presents a problem of increasing importance. strains of p. falciparum resistant to chloroquine have also been found to be resistant to amodiaquine and a combination of pyrimethamine and sulphadoxine. knowledge of the drug sensitivity of the strains of malaria parasite in a given locality is important so that the right choice of drugs can be made in treatment of the disease. the treatment of chloroquine resistant malaria ... | 1975 | 1095776 |
| studies on coagulation and fibrinolysis in cases of falciparum malaria. | coagulation and fibrinolytic studies were conducted in 18 cases of severe falciparum malaria including cases with parasitaemia above 5% and with pernicious manifestations such as coma, jaundice, anuria, pulmonary oedema, bleeding tendency, etc., irrespective of parasitaemia. marked changes in blood coagulograms and high levels of serum fibrin degradation products appeared only in cases with very severe cerebral involvement and also in cases with very high parasitaemia alone. these investigations ... | 1975 | 1096306 |
| comparison of diaminodiphenylsulphonepyrimethamine and sulfadoxine-pyrimethamine combinations in the treatment of falciparum malaria in thailand. | 1975 | 1096374 | |
| the rapid isolation from human blood of concentrated, white-cell-free preparations of plasmodium falciparum. | the sucrose gradient centrifugation method has been applied to representative samples of human (gambian) blood infected with ring, trophozoite, schizont and gametocyte stages of p. falciparum in order to assess quantitatively the efficiency of recovery, white cell removal and the degree of enrichment of the infected cell fraction. maximal white cell removal was 90%. (a.v.) average infected cell recoveries varied with the level of white cell contamination, namely 47% (2-5% wbc), 34% (1-2% wbc) an ... | 1975 | 1096379 |
| observations on malaria in indonesian timor. | malaria parasitemias were found in 35% of 520 individuals from a village in timor, indonesia. plasmodium falciparum accounted for 80% of infections. the existence of p. ovale in timor is reported for the first time. the who standard field test for drug resistance did not reveal significant resistance of p. falciparum or p. vivax to chloroquine. | 1975 | 1098490 |
| application of the indirect fluorescent antibody method in a study of malaria endemicity in mato grosso, brazil. | four surveys of malaria endemicity were conducted in the cuiabá sector of mato grosso state, brazil, at 6-month intervals during the period april 1970 to september 1971; during april 1970 a survey was also conducted in the campo grande sector. over 4,000 dual specimens--blood films for parasite diagnosis and filter paper blood spots for determination of fluorescent antibody (ifa) response--were collected from the general population, including school populations whenever possible. parasitologic e ... | 1975 | 1098491 |
| natural infections of anopheles albimanus with plasmodium in a small malaria focus. | entomologic surveys conducted in a small village in an area of known high malaria transmission in el salvador yielded a high rate of infection in anopheles albimanus collected inside houses in which cases of malaria had occurred. of 324 specimens dissected, 12 were found to harbor sporozoites or oocysts. this is in contrast to prior reports of extremely low infection rates in collections of this species from malarious areas, and suggests that under some circumstances a. albimanus does meet the c ... | 1975 | 1098498 |
| amodiaquine resistant falciparum malaria in thailand. | amodiaquine cured 38% (13/34) of patients with falciparum malaria in southeast thailand. chloroquine cured 0% (0/13). the cure rates with amodiaquine were the same whether a 1.5 g or 2.0 g course was used. most patients were resistant to amodiaquine at the ri level and to chloroquine at the rii level. in hospital, amodiaquine cleared parasitemia more frequently than did chloroquine. with the 2.0 g course of amodiaquine, the parasite clearance time was 77 hours; the fever clearance time of 36 hou ... | 1975 | 1098499 |
| chloroquine resistance of plasmodium falciparum in west irian and east kalimantan. | evidence is presented of the chloroquine-resistance in plasmodium falciparum in west irian and east kalimantan as shown by clinical observation and quantitative parasite counts in two patients hospitalized in tokyo where no natural transmission of malaria occurs. the evidence is supported by the determination of plasma chloroquine levels, and in vitro sensitivity tests. the highest plasma level of chloroquine in the patient infected in west irian was 197 ng/ml (fourth treatment) and 435 ng/ml (f ... | 1975 | 1098587 |
| studies on atp level in erythrocytes of patients with plasmodium falciparum malaria. | 1975 | 1099162 | |
| [malaria tropica--diagnosis and diagnostic errors]. | 1975 | 1099398 | |
| [letter: mechanism of hemolysis in the pernicious attack caused by plasmodium falciparum]. | 1975 | 1099538 | |
| [immunodiagnosis of malaria(author's transl)]. | 1975 | 1099572 | |
| malaria prophylaxis. | a trial of malaria prophylaxis was carried out on 744 army personnel who were camping in an endemic area over a 3-month period. three antimalarial drugs were used under strict control and the local population was used as a control, to prove that malaria was present during this time. no cases of malaria occurred in the trial group during this period. | 1975 | 1099692 |
| [duration of action of the pyrimethamine-sulfametopyrazine combination in a plasmodium falciparum endemic zone]. | the duration of action of the drug antemal, a combination of pyrimethamine and sulfametopyrazine, was eveluated in bobo-dioulasso, upper volta, west africa, and endemic zone for plasmodium falciparum malaria. the study was held during the season of maximum malaria transmission. 79 persons presenting with an acute attack of malaria were studied; 37 persons received a single dose of chloroquine sulfate (nivaquine), at a dose of 15 mg./kg.; 42 persons received a single dose of antemal at a dose of ... | 1975 | 1100287 |
| [malaria in children, with special reference to cerebral malaria (author's transl)]. | those who live in areas where malaria is endemic, acquire immunity by continuous contact. this immunity cannot be acquired during a short holiday. children in endemic areas acquire a more severe form of malaria during the period of developing immunity and more often suffer complications like acute hemolytic anemia and, in the case of plasmodium falciparum infection, cerebral malaria. this is a report of 39 cases of cerebral malaria which corresponds to an acute encephslopathy with high temperatu ... | 1975 | 1100897 |
| [problem of malaria and antimalarial measures in northern afghanistan. 1. malaria in northern afghanistan]. | 1975 | 1101014 | |
| [the problem of the transfer of malaria across the boundaries of the ussr]. | 1975 | 1101019 | |
| evidence for a malaria mitogen in human malaria. | 1975 | 1101075 | |
| probable chloroquine-resistant plasmodium falciparum malaria from mozambique a case report. | a female patient with plasmodium falciparum malaria apparently resistant to chloroquine is descirbed. she had recently returned from mozambique, which may prove to be a new endemic are with resistant strains. the infection was successfully treated with quinine. | 1975 | 1101388 |
| some effects of partial malaria suppression in ugandan children during the first 3 years of life. | 1975 | 1101459 | |
| letter: the durian season in peninsular malaysia as a factor in the epidemiology of malaria. | 1975 | 1101460 | |
| letter: multiple thick films on the same slide. | 1975 | 1101462 | |
| comparison of a 9-phenanthrene methanol (wr33063), a 4-quinoline methanol (wr30090), and quinine for falciparum malaria in thailand. | quinine was compared with a 9-phenanthrene methanol (wr33063) and a 4-quinoline methanol (wr30090) for the treatment of 207 patients with falciparum malaria in southeast thailand. quinine eradicated parasitaemia (average 70 hours) more rapidly than either wr30090 (72 hours) or wr33063 (77 hours). but wr33063 had a higher cure rate (92%) than wr30090 (86%) or quinine (85%). the mean duration of fever and of parasitaemia were combined with the failure rate to form an arbitrary efficacy index. usin ... | 1975 | 1101464 |
| longitudinal malaria studies in rural northeast thailand. chloroquine treatment of falciparum malaria infections. | the efficacy of chloroquine in the treatment of falciparum malaria was studied in two villages in northeast thailand, an area endemic for chloroquine-resistant falciparum infections. chloroquine did not appear to reduce the duration or density of parasitemias experienced by asymptomatic villagers, but did benefit, usually temporarily, many subjects with symptomatic or high-density infections. these observations suggest that the high prevalence of chloroquine-resistant infections in the villages ... | 1975 | 1101487 |
| applications of immunofluorescence to the seroepidemiology of malaria. | 1975 | 1101775 | |
| letter: malaria in britain. | 1975 | 1102056 | |
| the cytocentrifuge for the isolation of parasites from the blood. | 1975 | 1102109 | |
| fatal falciparum malaria among narcotic injectors. | eleven narcotic injectors from a prison in saigon were hospitalized with falciparum malaria. coma and intense parasitemia were common and eight patients died soon after admission. two of three autopsied cases also had purulent pulmonary infections. no non-addicted prisoners were hospitalized for malaria. nine more unsuspected falciparum infections were found among 29 other addicts in the prison. the clustering of malaria infections among narcotic injectors who had not been in malarious areas ind ... | 1975 | 1103639 |
| acetylator phenotype and response of individuals infected with a chloroquine-resistant strain of plasmodium falciparum to sulfalene and pyrimethamine. | acetylator phenotype was determined in 33 volunteers who were infected with a chloroquine-resistant strain of plasmodium falciparum and who received, for cure, 2 g of sulfalene and 50 mg of pyrimethamine. this drug combination did not cure 5 of 14 rapid acetylators and 3 of 19 slow acetylators. this difference is not significant. plasma levels of non-acetylated sulfalene, acetylated sulfalene, acetylation, and biologic half-life of non-acetylated sulfalene after administration of the combination ... | 1975 | 1103640 |
| the treatment of malaria. | 1975 | 1105541 | |
| mefloquine (wr 142,490) in the treatment of human malaria. | mefloquine hydrochloride, a new 4-quinolinemethanol, was administered as a single oral dose to 47 volunteers infected with malaria. treatment resulted in rapid clearence of fever and parasitemia. no recrudescence of parasites was observed after treatment of chloroquine-sensitive infections of plasmodium falciparum. more significantly, in nonimmune persons with chloroquine-resistant infections, 1 gram of mefloquine cured 10 of 12 patients and 1.5 grams cured all 8 patients who received this dose ... | 1975 | 1105787 |
| chemosuppressive field trials in thailand. ii. the suppression of plasmodium falciparum and plasmodium vivax parasitemias by a diformyldapsone-pyrimethamine combination. | in an area of thailand where chloroquine-resistant falciparum malaria is known to exist, a chemosuppressive field trial was undertaken to test the efficacy of the preparation diformyldapsone (dfd) combined with pyrimethamine (py) in suppressing falciparum and vivax parasitemias. six hundred and fifty-nine thai villagers were randomly assigned to one of five treatment groups: dfd-py; dapsone (dds)-py; dfd alone; py alone; and placebo. five hundred and ninety-three study subjects completed the 26- ... | 1975 | 1106229 |
| bilateral pleural effusions with plasmodium falciparum infection. | 1975 | 1106230 | |
| chloroquine in malaria chemotherapy. | 1975 | 1107292 | |
| evaluation of in vitro drug sensitivity of human plasmodium falciparum by incorporation of radioactive isoleucine. | 1975 | 1107459 | |
| editorial: new antimalarial agents. | 1975 | 1107583 | |
| comparative efficiency of pyrimethamine-sulphormethoxine in malaria suppression given as single weekly, fortnightly and monthly doses. | 2. one hundred and seventy inhabitants of the ilorin area, nigeria, were observed over a period of five months during the season of maximum malaria transmission while taking pyrimethamine-sulphormethoxine weekly, fortnightly and every four weeks. 2. there was no episode of malaria parasitaemia in the group receiving weekly doses of 25 mg. pyrimethamine and 0-5 mg. sulphormethoxine throughout the course of the trials. 3. there was one episode of asexual parasitaemia at the second month in the gro ... | 1975 | 1107584 |
| [the campaign against malaria at a crossroad]. | 1975 | 1107697 | |
| [50 cases of acute malaria: symptomatic study, especially cardiac]. | the authors have studied 50 records of patients who had presented an acute attack of p. falciparum malaria. both sexes were equally implied. young people were predominant. the distribution of cases was about the same in the whole year. the fever decreases on the second day and increases on the third day (300/0). among the classical signs: relative rarity of hepatomegalia (100/0), splenomegalia (10 0/0), jaundice (140/0), nervous symptoms (100/0). vomiting is rather frequent (30 0/0). from the ca ... | 1975 | 779991 |
| [evaluation of plasmodium falciparum antigen of human origin using indirect immunofluorescence reaction in malaria]. | the authors point out the use of p. falciparum antigens from man in the malaria ifa test. in malaria areas it is very easy to find them and although they are "coated" by antibodies they are quite valuable in significant titers. the use of p. falciparum from man is therefore very interesting for malaria diagnosis in non endemic areas and very useful for malaria surveys in endemic areas. | 1975 | 779993 |
| [malarial encephalopathy and disseminated intravascular coagulation (author's transl)]. | clinical and anatomical studies of a case of malarial encephalopathy are described in a 51 year old man. in view of the typical symptomatology it was important to ascertain an period even brief of stay in an endemic area. only when this was confirmed the appropriate investigations could be planned (in thic case thick blood drop test) to identify the parassite. the physiopathological mechanisms through which the malarial infection causes the parenchymal lesions are considered. such lesions accord ... | 1975 | 778999 |
| persistence and recurrence of s-antigen in plasmodium falciparum infections in man. | the persistence of heat stable malarial antigens (s-antigens) in the sera of gambian children following treatment for severe plasmodium falciparum infections was investigated. in most cases s-antigens ceased to be demonstrable within 7 days but in some they were detected for several weeks and their persistence correlated with both the density of parasitaemia and the antigen titre observed before treatment. an exponential loss of circulating antigen was, in the majority of individuals, accelerate ... | 1975 | 779155 |
| letter: response of ethiopian strains of plasmodium falciparum to amodiaquine. | 1975 | 779158 | |
| complement and malaria. | 1976 | 779685 | |
| [results of a survey on post-transfusional malaria in france between 1960 and 1974]. | this inquire demonstrated that transfusion malaria was not so rare as we thought. so 56 cases have been numbered between 1960 and 1974, and probably they do not reflect exactly the real situation. in our country, plasmodium falciparum, specifically responsible of the most serious accidents, is the form most frequently incriminated and its frequency increases among the years: 76,1% of the infects between 1970 and 1974. at last we have confirmed that a prevent of those accidents must consider as a ... | 1976 | 981874 |
| ferrokinetics in patients with malaria: haemoglobin synthesis and normoblasts in vitro. | bone marrow cultures in 15 plasmodium falciparum patients were studied both during and after parasitaemia. abnormalities were observed only in the group during parasitaemia. these abnormalities included: (1) decreased normoblastic number and cellular iron incorporation in all cases; (2) premature death of normoblasts during their development in the cultures in all cases; (3) defective haemoglobin synthesis in 3 of 11 cases (27%). a causal relationship between defective haemoglobin synthesis and ... | 1976 | 982520 |
| parasitological survey in gorontalo north sulawesi, indonesia. | a survey for blood and intestinal parasites was carried out in the municipality of gorontalo on the minahasa peninsula of north sulawesi. a total of 156 stool specimens were obtained from 83 males and 73 females. trichuris trichiura, ascaris lumbricoides, hookworm, unidentified dicrocoeliid-like ova and entamoeba coli, in that order, were the most common intestinal parasites detected. other intestinal parasites found less frequently were entamoeba histolytica, iodamoeba bütschlii, endolimax nan ... | 1976 | 1030844 |
| peripheral lymphocyte subpopulations in human falciparum malaria. | the concentration of circulating t, b, and 'null' lymphocytes was determined in thirty children and three adults with plasmodium falciparum infections in west africa. during infection, both percentage as well as concentration of t cells were decreased as compared to levels following treatment. the percentage but not concentration of b cells was increased. both percentage and concentration of 'null' cells were increased in malaria. patients with splenomegaly had the most severe alterations in t-c ... | 1976 | 780013 |
| malaria eradication and control from a global standpoint. | 1976 | 781250 | |
| human malaria parasites in continuous culture. | plasmodium falciparum can now be maintained in continuous culture in human erythrocytes incubated at 38 degrees c in rpmi 1640 medium with human serum under an atmosphere with 7 percent carbon dioxide and low oxygen (1 or 5 percent). the original parasite material, derived from an infected aotus trivirgatus monkey, was diluted more than 100 million times by the addition of human erythrocytes at 3- or 4-day intervals. the parasites continued to reproduce in their normal asexual cycle of approxima ... | 1976 | 781840 |
| malaria - the mime. recent lessons from a group of civilian travellers. | clinical data on 24 civilian patients hospitalized for malaria in the new york hospital were analyzed. of 16 patients infected with plasmodium falciparum, 14 acquired the disease in west africa. only three of the 24 had taken recommended courses of prophylaxis. diagnosis was invariably, and often dangerously, delayed because physicians often made diagnoses of viral syndromes or used antibiotics; only one patient had a blood smear taken by a personal physician. although all patients had fever and ... | 1976 | 782238 |
| malaria at the hospital for sick children, toronto. | the number of immigrants to canada from countries where malaria is endemic increased sevenfold between 1964 and 1974. from january 1973 through july 1975, 15 cases of malaria were treated at the hospital for sick children, toronto. the only symptom common to all patients was fever, and it was not always cyclic. for any child with a fever of unknown cause who has been in a region where malaria is endemic within the previous 6 months, a blood smear should be examined for parasites. if the smear is ... | 1976 | 782677 |
| symptoms and signs of malaria. | in addition to asking their patients about recent foreign travel, canadian doctors need to be aware of what features to ask about in considering imported illnesses. of these illnesses, malaria is one of the most common and serious. because of its cerebral renal, pulmonary and intestinal complications, falciparum malaria must be distinguished from non-falciparum forms. anyone with a fever who has arrived recently from an endemic area should be tested for malaria. in addition, headache, malaise, m ... | 1976 | 782678 |
| lung uptake of 99mtc-sulfur colloid in falciparum malaria: case report. | increased lung uptake of 99mtc-sulfur colloid was seen during liver scanning in a patient with falciparum malaria. this finding was due to the enhanced activity of the phagocytic cells of the reticuloendothelial system in the liver, spleen, and lung found in human and experimental malaria. similar findings in other clinical situations and the relevant literature are reviewed. | 1976 | 784917 |
| studies on the resistance of malaria to chloroquine and to a combination of chloroquine and pyrimethamine in peninsular malaysia. | in vivo chloroquine resistance surveys, which allowed for detection of late recrudescing ri resistance, were conducted in three regions of peninsular malaysia, which were previously not recognized as having appreciable drug resistance. among the 485 plasmodium falciparum infections tested resistance rates ranged locally from 20% to 67% in those with parasitaemias over 1,000 per mm3, and 5% to 59% in all parasitaemias. the region found to have the most serious resistance was western pahang. in on ... | 1976 | 785725 |
| two cases of malaria presenting with psychiatric symptoms. | mood and behavior disorder may appear either due to primary psychiatric disorder or may signify an underlying, frequently undetected, physical pathology. two instances of malaria falciparum presenting with psychosocial symptomatology are described. | 1976 | 786382 |
| a study of the clinical features of malaria in rhodesia. part iii. african children. | 1976 | 786460 | |
| lack of a circadian rhythm in the ability of the gametocytes of plasmodium falciparum to infect anopheles gambiae. | 1976 | 786919 | |
| method to test inhibitory antibodies in human sera to wild populations of plasmodium falciparum. | 1976 | 787801 | |
| [the treatment of severe tropical malaria]. | 1976 | 787812 | |
| [tropical malaria infections. diagnostic and therapeutic problems]. | 1976 | 1107745 | |
| [salmonella bacteremia and cerebral malaria. a case with fatal coincidence of 2 imported diseases]. | 1976 | 1108331 | |
| acute renal failure in tropical africa. | between 1972 and 1975, 55 adult patients with acute renal failure were admitted to the renal unit of korle bu hospital. fourteen patients died, giving an overall death rate of 25%. massive intravascular haemolysis after a short febrile illness was the commonest cause of acute renal failure. clinically these patients presented with blackwater fever but in only one could plasmodium falciparum malaria be confidently diagnosed. in half the patients various bacterial and viral infections (especially ... | 1976 | 1260396 |
| relapse in malaria--an enigma. | 1976 | 815536 | |
| the effect of human immune igg on the in vitro development of plasmodium falciparum. | plasmodium falciparum parasites infecting aotus trivirgatus erythrocytes were cultured in media (harvard and tc199) augmented with human, foetal calf, or other sera. conditions were established which supported growth of parasites and allowed cyclical multiplication when fresh erythrocytes (from aotus or homo) were added in sub-culture (mean multiplication rate: x3). immunoglobulin g pools, prepared from plasma collected in endemic malarious areas in africa and from unexposed britons, were teste ... | 1976 | 817249 |
| experimental infection of aotus monkeys with plasmodium falciparum light and electron microscopic changes. | six splenectomized aotus owl monkeys were infected with p. falciparum. the animals were sacrificed when they became moribund and tissues were faken for light and electron microscopic studies. electron microscopy revealed marked structural changes in both the liver and the heart. in the liver there was glycogen depletion, lipid droplet infiltration mitochondrial disorganization with reduction in numbers and alterations of the microvilli in the sinusoidal pole and the bile canaliculi. in the heart ... | 1976 | 817680 |
| malarial infections in aotus trivirgatus with special reference to liver pathology. | 1976 | 819657 | |
| [chemotherapy and chemoprophylaxis of malaria (author's transl)]. | chloroquine and amodiaquine are demonstrably still the most reliable drugs for the treatment of malaria, except in the south east asia area, and in parts of south and central america where an altered sensitivity of falciparum plasmodia has been confirmed. the present position of malaria prophylaxis is, unfortunately, anything but satisfactory. but there are already some good preparations which, if correctly used with consideration of all available information, contribute considerably to the prev ... | 1976 | 822313 |
| [serodiagnosis of malaria (author's transl)]. | homologous and heterologous malaria pathogens were used as antigens for the determination of malaria antibodies by indirect immunofluorescence. homologous antibodies fell in the second half year, after successful treatment, down to the limit of demonstrability. in inhabitants of endemic malarial areas, who lived in the german federal republic, signs of a fall in antibodies could be observed after about 30 months. the predominance of particular malaria pathogens of the country of origin was recog ... | 1976 | 823409 |
| [different types of gametocytes in mammal's haemosporidia. correlations with the morphology of the tissue schizonts. hypothesis on the evolution of the group (author's transl)]. | the haemosporidia of mammals are classified in 3 groups according to the morphology of the gametocytes: 1) group "vivax" with hepatocystis and several species of plasmodium; 2) group "malariae" with nycteria and a second group of plasmodium; 3) group "falciparum" with only plasmodium. in each group there is a correlation between the morphology of the gametocytes and that of the exo-erythrocytic schizonts. through discussing the host-range and comparing the life cycles of haemosporidia in birds, ... | 1976 | 823859 |
| [unusual infectious diseases in a municipal hospital (author's transl)]. | the most important criteria for differential diagnosis are presented with reference to case histories: falciparum malaria: relapsing fever, hemolytic anemia, hepatosplenomegaly, leucopenia; kala-azar: insidious course with fever, pancytopenia, macrocytic anemia, hepatosplenomegaly, enlargement of lymph nodes; echinococcosis: symptoms of a benign tumor with displacement. diagnosis: by identification of the pathogen in malaria and kala-azar, serologically in all three diseases and also radiologica ... | 1976 | 825760 |
| culture of human malaria parasites plasmodium falciparum. | 1976 | 825784 | |
| studies with induced malarias in aotus monkeys. | aotus monkeys have been shown to be susceptible to the three most important species of human malaria as well as to simian, ape, and rodent malaria. the parasites natural to man were maintained by serial passages using trophozoite infected blood. it was then possible to transfer the infections to, and among, other new world monkeys which previously were refractory. the parasites retained their viability in the monkey, were infective to mosquitos, and were transmitted between monkeys and back to m ... | 1976 | 828228 |
| the quartan malarial nephrotic syndrome. | a specific relationship between p. malariae and the nephrotic syndrome, originally postulated on epidemiologic evidence, has been substantiated by clinical, pathologic and immunologic observations. it would appear that quartan malaria causes an immune complex nephritis in some individuals that, once established, is sustained by mechanisms not yet fully explained but which may involve an autoimmune process. evidence to support an immunologic pathogenesis of the renal lesions is provided by the pr ... | 1976 | 828446 |
| malaria guidelines: cdc recommended treatment schedules, 1974. | 1976 | 776514 | |
| [letter: transplacental passage of soluble plasmodial antigens. induction of a specific immune tolerance?]. | 1976 | 778794 | |
| the prevalence of babesia antibodies in nigerians. | 1976 | 770357 |