Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| internal standards for gas chromatographic analysis of metabolic end products from anaerobic bacteria. | 2-methylpentanoic acid and benzoic acid are suggested for use as routine internal standards for gas chromatographic analysis of microbial end products. | 1977 | 869521 |
| experimental bacteroides fragilis endocarditis in rabbits. | a serum-resistant strain of bacterioides fragilis that did not produce heparinase was used to study the characteristics of b. fragilis endocarditis in the rabbit experimental model. the infective dose required to produce endocarditis in 50% of rabbits was significantly lower for rabbits with left-sided intracardiac catheters (log10 6.3 colony-forming units +/- 0.6/ml) as compared with right-sided intracardiac catheters (log10 7.7 colony-forming units +/- 0.8/ml). after 3 days of infection, bacte ... | 1977 | 870433 |
| fatal colitis in a hemophilic patient with inhibitor. | a severe colitis developed in a hemophilic patient following an antibiotic regimen which included clindamycin. a surgical procedure, total hip replacement, had been complicated by the appearance of a powerful factor viii inhibitor and a bacteroides fragilis infection. the resulting bleeding diathesis was successfully managed with the use of an "activated prothrombin complex"; however, the occurrence of colitis following intravenous clindamycin therapy proved to be fatal. clindamycin, like the re ... | 1977 | 870986 |
| development of anaerobic fecal flora in healthy newborn infants. | stool samples from 196 healthy infants less than ten days of age were cultured to delineate bacterial colonization patterns of the intestine. by one week of age, isolation rates of bacteroides fragilis and other anaerobic bacteria in term infants following vaginal delivery and formula feeding approach that of adults. differences in gestational age, type of delivery, and type of feeding are associated with significantly different colonization patterns of anaerobic and aerobic bacteria in the firs ... | 1977 | 874690 |
| synergistic action of erythromycin and cefamandole against bacteroides fragilis subsp. fragilis. | erythromycin and cefamandole have exhibited synergistic activity against eight strains of bacteroides fragilis subsp. fragilis. in concentrations of only 0.25 to 0.5 mug of erythromycin per ml (easily obtainable with oral therapy), less than 0.4 mug (0.015 to 1.0) of cefamandole per ml inhibited the b. fragilis strains. in the presence of the erythromycin, the potency of cefamandole was increased more than 100-fold. on the basis of the mechanism of action of these two antibiotics, the synergism ... | 1977 | 879736 |
| susceptibility of anaerobic bacteria to cofoxitin and related compounds. | cephalothin, cefazolin, cephradine, and cefoxitin inhibited more than 75% of 326 anaerobic bacteria in vitro, but cefoxitin was the most effective against anaerobes in general and bacteroides fragilis in particular. | 1977 | 879743 |
| laminarinase (beta-glucanase) activity in bacteroides from the human colon. | laminarin, a beta(1 leads to 3)-glucan similar to those found in plant cell walls, is fermented by some species of anaerobic bacteria from the human colon. laminarinase (ec 3.2.1.6) and beta-glucosidase (ec 3.2.1.21) activities were determined in strains representing bacteroides thetaiotaomicron, bacteroides distasonis, and an unnamed deoxyribonucleic acid homology group of bacteroides fragilis. in all three species, laminarinase activity was inducible by laminarin and was predominantly cell bou ... | 1977 | 879772 |
| cefuroxime, a new parenteral cephalosporin: collaborative in vitro susceptibility comparison with cephalothin against 5,887 clinical bacterial isolates. | cefuroxime, a new parenteral cephalosporin was compared with cephalothin by broth microdilution susceptibility testing against 5,887 routine clinical bacterial isolates in four large clinical laboratories. the minimal inhibitory concentrations (mics) of cefuroxime against the enterobacteriaceae were consistently lower than those of cephalothin. this was most striking among the enterobacter species, which were generally susceptible to cefuroxime (mic </= 8 mug/ml), but resistant to cephalothin. s ... | 1977 | 883818 |
| the capsular polysaccharide of bacteroides fragilis as a virulence factor: comparison of the pathogenic potential of encapsulated and unencapsulated strains. | the pathogenic potentials of encapsulated and unencapsulated strains of bacteroides fragilis were compared by use of a rat model of intraabdominal sepsis. implantation of encapsulated b. fragilis alone resulted in abscesses in most recipients, whereas unencapsulated strains seldom produced this effect unless they were combined with another organism. implants of heat-killed, encapsulated b. fragilis also resulted in abscess formation. subsequent experiments suggested that the abscess-potentiating ... | 1977 | 886206 |
| [necrosing postoperative enteritis with septicemia due to bacteroides fragilis (ristella)]. | 1977 | 887393 | |
| bl-s786, a new parenteral cephalosporin. i. a collaborative in vitro susceptibility comparison to cephalothin against 5,762 clinical bacterial isolates. | the in vitro activity of compound bl-s786 was compared with that of cephalothin against 5,762 clinical isolates by the microdilution broth method. bl-s786 demonstrated a broader spectrum and a significantly lower mic against the enterobacteriaceae. although greater susceptibility to bl-s786 than to cephalothin was exhibited by serratia marcescens, proteus morganii and proteus vulgaris, these three species were generally resistant to both drugs. by contrast, the staphylococci were significantly m ... | 1977 | 893226 |
| hydrogenase activity and the h2-fumarate electron transport system in bacteroides fragilis. | hydrogenase activity and the h(2)-fumarate electron transport system in a carbohydrate-fermenting obligate anaerobe, bacteroides fragilis, were investigated. in both whole cells and cell extracts, hydrogenase activity was demonstrated with methylene blue, benzyl viologen, flavin mononucleotide, or flavin adenine dinucleotide as the electron acceptor. a catalytic quantity of benzyl viologen or ferredoxin from clostridium pasteurianum was required to reduce nicotinamide adenine dinucleotide or nic ... | 1977 | 893348 |
| bacteroides in pelvic abscesses. | 1977 | 895814 | |
| [treatment of meningitis caused by bacteroides fragilis with injections of ornidazole]. | 1977 | 896422 | |
| [isolation of bacteroides fragilis from the appendix in a case of appendicitis]. | 1977 | 896576 | |
| bacteriology of cholesteatoma: clinical significance. | 1977 | 898521 | |
| bs ii lectin: a second hemagglutinin isolated from bandeiraea simplicifolia seeds with affinity for type iii polyagglutinable red cells. | bs ii lectin, a second hemagglutinin isolated from bandeiraea simplicifolia seeds, agglutinated the red cells from 11 patients manifesting the 'acquired b' antigen phenomenon. the results of serological studies indicate that this lectin has specificity for the type iii polyagglutinable receptors rather than for the 'b-like' antigens present on 'acquired b' red cells. two other blood samples which did not possess 'acquired b' antigens were also found to react with bs ii lectin. both of these samp ... | 1977 | 898840 |
| [increase of anaerobic infections. prevalence of bacteroides. apropos of 17 cases in abdominal surgery]. | seventeen cases of anaerobic infections in abdominal surgery are reported. predominance of bacteroides is evident (9/17), especially bacteroides fragilis. the clinical manifestations of bacteroides infections are severe: 7 septicemias and 2 parietal infections, being the cause of the death in four patients. bacteroides infection develops preferently in an old patient, with severe disease, in colic surgery especially in emergency. bacteroides are characterized by their polyresistance to antibioti ... | 1977 | 900536 |
| bacteroides fragilis infections of the urinary tract. | 1977 | 903332 | |
| susceptibility bacteroides fragilis to fusidic acid. | 1977 | 903333 | |
| [appearance of metronidazole resistance in bacteroides fragilis]. | 1977 | 905136 | |
| the cephalosporins. | cephalosporin antibiotics are bactericidal against most gram-positive cocci and many gram-negative bacilli of clinical importance. they are relatively nontoxic but share with penicillins a tendency to elicit hypersensitivity reactions. they are indicated in certain instances for treatment of infections in patients with penicillin allergy and are frequently chosen as one of the agents in an empiric program in life-threatening infections. cephalosporins should not be used in infections caused by g ... | 1977 | 909313 |
| [bacteroides fragilis septicemia during rheumatoid arthritis]. | 1977 | 909745 | |
| in vitro activity of five oral cephalosporins against anaerobic pathogenic bacteria. | the in vitro inhibitory activities of cefaclor and and cefatrizine, two new orally absorbed cephalosporin antibiotics, against 44 isolates of anaerobic pathogenic bacteria were measured using the agar dilution procedure of the world health organization-international collaborative study. tests also were performed with cephalexin, cephaloglycin, and cephadrine, as well as with the parenteral cephamycin antibiotic cefoxitin. cefoxitin was the most active antibiotic and inhibited the majority of iso ... | 1977 | 915342 |
| [evaluation of the disc-plate method in bacteroides fragilis]. | 1977 | 918321 | |
| requirement of heme for growth of bacteroides fragilis. | heme or protoporphyrin ix was required for growth of bacteroides fragilis in a defined medium. the amount of heme necessary for half-maximal growth was 2 to 10 ng/ml (3.8 to 15 pmol/ml) among the bacteroides species and strains tested. the growth rate, metabolic products from glucose fermentation, and cell yields were affected by the concentration of heme in the medium and by the length of time the culture was incubated. when heme was growth limiting (4 ng/ml), growth rates decreased by 50%, cul ... | 1977 | 921263 |
| treatment of cerebral abscesses. | 1977 | 922393 | |
| bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazole. | in nine consecutive patients with otogenic cerebral abscesses a mixed growth of aerobic and obligate anaerobic bacteria was isolated from the pus in five patients, and in the remaining four obligate anaerobes were the sole isolates. the commonest obligate anaerobe isolated was bacteroides fragilis, which was present in all but one patient. the patients were all treated with metronidazole for the anaerobic organisms and with appropriate chemotherapy against the aerobic organisms isolated. all the ... | 1977 | 922400 |
| evaluation of kanamycin-esculin bile agar for isolation and presumptive identification of bacteroides fragilis group. | a kanamycin-esculin bile medium was useful for selective isolation and presumptive identification (24 h) of the bacteroides fragilis group. | 1977 | 925149 |
| effect of some bacterial products on platelet electrophoretic mobility (pem). | bacterial lps, used in our experiments, are able to decrease pem at concentration of 100 microgram/ml after incubation with 1 x 10(7) platelets/ml for 30 min at 37 degrees c. such effect is statistically significant for bacteroides fragilis lps, s. enteritidis and s. typhi. e. coli lps 026:b6 w and e. coli 055:b5 w are not effective at all, s. minnesota (incomplete) lps 595 and 345 free of 0-polysaccharide and partially lacking core in their molecule did not influence pem, while s. minnesota lps ... | 1977 | 410424 |
| anterograde transneuronal degeneration in the limbic system: clinical-anatomic correlation. | a 64-year-old man with diffuse atherosclerosis developed an organic mental syndrome, followed by hypothalamic symptoms. autopsy showed an old large cystic infarct involving the left temporal lobe including the hippocampus, and atrophy of the ipsilateral fornix, mammillary body, hypothalamus, mammillothalamic tract, and the anterior thalamic nucleus. the clinical deterioration and pathologic findings may be explained by anterograde transneuronal degeneration within the limbic system following the ... | 1977 | 412120 |
| acute pelvic inflammatory disease. | 1977 | 412258 | |
| [bacteroides fragilis (author's transl)]. | 1977 | 559144 | |
| [anaerobic bacterial infections (author's transl)]. | 1977 | 560553 | |
| office treatment of anaerobic infections. | 1977 | 561288 | |
| lethality for mice and chick embryos, pyrogenicity in rabbits and ability to gelate lysate from amoebocytes of limulus polyphemus by lipopolysaccharides from bacteroides, fusobacterium and veillonella. | phenol-water extracted lipopolysaccharides (lps) from veillonella, fusobacterium nucleatum, bacteroides fragilis and bacteroides melaninogenicus were lethal for mice and 11-days-old chick embryos, pyrogenic in rabbits, and gelated limulus amoebocyte lysate. mouse lethality was considerably enhanced by actinomycin-d. in all test systems the endotoxin activity of veillonella and fusocbacterium lps was comparable to that of lps from salmonella enteritidis, which was included as a reference endotoxi ... | 1977 | 564596 |
| [isolation of anaerobic bacteria from clinical specimens and the drug susceptibility of bacteroides fragilis]. | in the routine bacteriological examination of 8,423 clinical specimens, 906 strains of anaerobic bacteria were isolated at national taiwan university hospital between april 1972 and april 1976. most of the strains were isolated from sites allied to the abdominal cavity and genito-urinary tract. bacteroides fragilis was the most commonly isolated pathogen. the minimal inhibitory concentrations of 10 different antimicrobial agents to 74 clinical isolates of b. fragilis were determined by an agar d ... | 1977 | 578133 |
| doxycycline in abdominal surgery. | twenty patients undergoing urgent or emergency surgical procedures where intra-abdominal infection was suspected were treated with doxycycline hyclate. wound infections involving anaerobic, aerobic, or facultative bacteria developed in four of 11 patients treated with doxycycline alone. nine other patients received higher doses of doxycycline plus gentamicin sulfate. five of these had postoperative infections primarily involving anaerobic organisms. bacteremia with a doxycycline-resistant bacter ... | 1977 | 578553 |
| susceptibility to erythromycin of anaerobes of the genera bacteroides, fusobacterium, sphaerophorus, veillonella, clostridium, corynebacterium, peptococcus, peptostreptococcus. | the minimal inhibitory concentrations (mic) of erythromycin were determined by broth dilution tests for 313 anaerobic strains, most of which were clinical isolates. all the gram-positive anaerobes tested (84 peptococcaceae, including 21 peptostreptococcus anaerobius and 15 peptococcus variabilis; 65 corynebacterium acnes and 29 clostridium strains, including 13 c. perfringens) were sensitive (mic values 0.012 through 3.12 microgram erythromycin/ml); so were 111 cultures of gram-negative anaerobe ... | 1977 | 580038 |
| [anaerobic infections]. | 1977 | 584899 | |
| [in vitro activity of mezlocillin, azlocillin and carbenicillin against bacteroidaceae with particular reference to bacteroides fragilis (author's transl)]. | the in vitro susceptibility of approximately 90 bacteroidaceae strains to the the new broad-spectrum penicillins mezlocillin and azlocillin was determined by tube dilution tests and compared to susceptibility to carbenicillin. bacteroides fragilis and bacteroides thetaiotaomicron predominated among the strains tested. these strains are particularly important as pathogens and are known to produce beta-lactamase. at concentrations of 16 microng/ml or less, mezlocilin inhibited 81% of the bacteroid ... | 1977 | 585371 |
| susceptibility of bacteroides to noxythiolin. | 1977 | 589283 | |
| the degradation of cholic acid and deoxycholic acid by bacteroides species under strict anaerobic conditions. | 1977 | 598575 | |
| an h.p.l.c. assay for cephalosporinase activity. | 1977 | 599089 | |
| bactericidal activity of metronidazole, tinidazole and ornidazole against bacteroides fragilis in vitro. | 1977 | 599119 | |
| discrepant behaviour of clotrimazole against bacteroides fragilis in liquid and solid media. | 1977 | 599124 | |
| erythromycin and anaerobic infection. | the theoretical basis of the use of erythromycin in peri-operative prophylaxis after bowel surgery will be discussed and the results of the use of erythromycin in such patients and the sensitivity to the antibiotic of isolates from human peritonitis described. this work will be related to results obtained in a rabbit experimental model for the study of peritonitis. | 1977 | 601557 |
| comparison of in vitro activity of cephalexin, cephradine, and cefaclor. | inhibitory activity of cephalexin, cephradine, and cefaclor was compared by the who-ics agar dilution technique. cefaclor was substantially more active against staphylococci, streptococci, gonococci, meningococci, haemophilus, escherichia coli, klebsiella pneumoniae, citrobacter diversus, proteus mirabilis, salmonellae, and shigellae than was cephalexin, which in turn was more active than cephradine. cefaclor appeared to be less resistant to staphylococcal penicillinase than did the other two ag ... | 1977 | 301005 |
| studies with cefuroxime and cefoxitin. | we have studied cefuroxime, a new beta-lactamase resistant cephalosporin, and cefoxitin, the first cephamycin antibiotic, which is also resistant to many beta-lactamases. both of these antibiotics have been shown to be microbiologically superior to the "first generation" cephalosporins, cefuroxime having notable activity against haemophilus influenzae, and cefoxitin against bacteroides fragilis. neither antibiotic is absorbed from the gut but, following parenteral administration, serum, urine an ... | 1978 | 308260 |
| beta-lactamases of subspecies of bacteroides fragilis. | 1978 | 308502 | |
| factors affecting antimicrobial agents in an anaerobic abscess. | 1978 | 308504 | |
| cefotoxime (hr 756) a new cephalosporin with exceptional broad-spectrum activity in vitro. | 1978 | 308505 | |
| activity of hr 756 against haemophilus influenzae, bacteroides fragilis and gram-negative rods. | 1978 | 308506 | |
| apparatus for uniaxial testing of soft human tissues in vitro. | 1978 | 309051 | |
| influence of inflammatory bowel disease on intestinal microflora. | the microflora of the jejunum, ileum, and colon has been studied from operative samples in crohn's disease (n = 30), ulcerative colitis (n = 15), and controls (n = 40). there was no significant difference in the flora of patients with ulcerative colitis compared with controls. in crohn's disease there was a significant increase in e. coli (p less than 0.001) and b. fragilis (p less than 0.001) in the ileum and of e. coli (p less than 0.001) and lactobacilli (p less than 0.01) in the colon. the a ... | 1978 | 369959 |
| effects of storage in an anaerobic transport system on bacteria in known polymicrobial mixtures and in clinical specimens. | an anaerobic transport system (ats) which provides for catalytic removal of oxygen was evaluated by using in vitro-prepared polymicrobial mixtures of logphase bacteria and clinical specimens. inoculated swabs were stored at room temperature in (i) aerobic, (ii) anaerobic glove box, and (iii) ats environments, and bacteria were quantitated after 2, 24, 48, and 72 h. bacteria in a three-part mixture of bacteroides fragilis, peptostreptococcus anaerobius, and escherichia coli and in a five-part mix ... | 1978 | 370142 |
| evaluation of a routine anaerobic subculture of blood cultures for detection of anaerobic bacteremia. | the value of a routine 48-h anaerobic subculture of blood cultures was assessed in our laboratory over a 4-month period. excluding presumed contaminants, anaerobes represented 51 (6.9%) of the total number of 734 positive cultures. sixteen isolates (all bacteroides) from six patients were detected by the anaerobic subculture. all but one of these were also detected macroscopically. excluding the one isolate, the routine anaerobic subculture hastened the identification of anaerobic organisms by o ... | 1978 | 370151 |
| antimicrobial activity of metronidazole in anaerobic bacteria. | the antimicrobial activity of metronidazole was investigated in anaerobic bacteria by use of time-viability studies. this antimicrobial agent has a rapid onset of bactericidal activity under proper reducing conditions. the bactericidal rates were not affected by inoculum size or nutritional requirements, nor by inhibition of growth and protein synthesis by chloramphenicol. using supernatant fractions of actively growing cultures of susceptible organisms, we observed a disappearance of metronidaz ... | 1978 | 233729 |
| the role of bacteroides fragilis in abcesses of the central nervous system: implications for therapy. | 1978 | 624699 | |
| enhancement of experimental anaerobic infections by blood, hemoglobin, and hemostatic agents. | certain foreign materials have been demonstrated to enhance the infectivity of aerobic and anaerobic bacteria. whole blood and other protein compounds encountered in surgical settings or trauma were tested for their effect on infectivity of nonsporeforming anaerobic bacteria. infectious synergistic mixtures of bacteroides fragilis plus peptostreptococcus anaerobius and bacteroides melaninogenicus plus fusobacterium necrophorum were each diluted to a barely noninfectious or minimally infectious c ... | 1978 | 631883 |
| adherence of bacteroides fragilis in vivo. | the ability of the encapsulated species bacteroides fragilis to adhere to rat peritoneal mesothelium was compared to the adherence of unecapsulated strains of bacteroides (b. distasonis, b. vulgatus, b. thetaiotaomicron, b. ovatus, and b. "other"). adherence was assayed by attaching plexiglas plates containing 8-mm holes to the peritoneal mesothelium of anesthetized rats. cell suspension (0.25 ml) was incubated in each well, after which the suspension was aspirated, and a 4-mm punch biopsy was r ... | 1978 | 640723 |
| encapsulation of bacteroides species. | capsules were detected by the india ink method in cultures of bacteroides fragilis, b. vulgatus, b. thetaiotaomicron, and b. ovatus. no capsules were found in the five strains of b. distasonis examined. | 1978 | 640724 |
| [infections caused by bacteroides fragilis resistant to clindamycin: 2 further cases]. | 1978 | 643586 | |
| use of high-pressure liquid chromatography to determine plasma levels of metronidazole and metabolites after intravenous administration. | a rapid and sensitive high-pressure liquid chromatography assay for metronidazole and its two principle metabolites, 1-(2-hydroxyethyl-2-hydroxymethyl)-5-nitro-imidazole [hydroxy metabolite] and 1-acetic acid-2-methyl-5-metronidazole [acid metabolite], was developed. the retention times observed were 5.7, 3.3, and 4.5 min, respectively. a reverse-phase muc(18) bondapak column using a solvent system of methanol, acetonitrile, and 0.005 m ph 4 potassium dihydrogen phosphate (4:3:93, vol/vol) was u ... | 1978 | 646342 |
| bacteroides fragilis endotoxin-induced histopathological lesions in mice and rabbits. | 1978 | 647432 | |
| breakdown of psyllium hydrocolloid by strains of bacterioides ovatus from the human intestinal tract. | strains of bacteroides ovatus from human feces produced extracellular enzymes which degraded psyllium hydrocolloid. other species of saccharolytic bacteria which are found in high concentrations in human feces did not degrade psyllium. | 1978 | 647481 |
| a study of the surface and somatic antigens of bacteroides fragilis. | antisera against live cultures of 20 strains of bacteroides fragilis produced in rabbits agglutinated homologous whole-cell as well as o-antigen suspensions with several cross-reactions. pure specific antisera were produced by absorbing cross-reacting antigens. o-antisera reacted against o-antigens but failed to do so against most whole-cell suspensions, suggesting the presence of surface structures which might have blocked the reactions. the titres of the whole-cell antisera were not significan ... | 1978 | 649950 |
| inactivation of penicillin g during experimental infection with bacteroides fragilis. | an animal model implanted with intraperitoneal plastic reservoirs was used for study of the penetration of penicillin g into sites infected with bacteroides fragilis. penicillin g was given to rabbits, and its concentration in uninfected reservoirs and in those infected with b. fragilis was determined. the mean percentage penetration ([concentration in capsule divided by peak concentration in serum] x 100) of penicillin into uninfected capsules was 19.9%, whereas that into heavily infected capsu ... | 1978 | 649987 |
| clinical experience with cefamandole for treatment of serious bone and joint infections. | the safety and efficacy of treatment with cefamandole were evaluated in 30 patients (from 18 institutions) with serious bone and joint infections. five of the subjects were children. the antibiotic was given intramuscularly or intravenously in doses ranging from 2 to 12 g daily for five to 44 days. twenty-six of the 30 patients responded satisfactorily. fourteen of the fifteen infections due to staphylococcus aureus were among the successful cases. other pathogens were streptococci, escherichia ... | 1978 | 649996 |
| a case of septic arthritis in multiple joints due to bacteroides fragilis in a patient with rheumatoid arthritis. | a case of arthritis in multiple joints due to b. fragilis ssp. fragilis is described. the patient was a 55-year-old man badly disabled by rheumatoid arthritis. the patient's immune response to the isolated strain was studied and a significant titre reduction during the course of the disease was observed. the serum antibodies of the patient cross-reacted with heterologous strains of b. fragilis ssp. fragilis. it is suggested that indirect immunofluorescence tests against a certain number of b. fr ... | 1978 | 654904 |
| quantitative gas chromatography of bacteroides species under different growth conditions. | from 56 strains of strictly anaerobic gram-negative rods isolated from stool and purulent lesions the fermentation products in the presence and absence of hemin were determined by quantitative gas-solid chromatography, using a simple and more rapid chromatographic procedure. with hemin the fermentation products were propionic, acetic, lactin and succinic acid. without hemin no or little succinic acid was formed and the main products were lactic and acetic acid. in both groups the distribution of ... | 1978 | 655693 |
| new medium for selection and presumptive identification of the bacteroides fragilis group. | a medium, bacteroides fragilis bile-esculin (bbe) agar, was designed for the selection and, presumptive identification of the b. fragilis group. bbe agar contains bile, esculin, ferric ammonium citrate, hemin, and gentamicin in a trypticase soy agar base. growth in the presence of 20% bile and esculin hydrolysis, detected by blackening of the medium, provide presumptive evidence for the identification of the b. fragilis group. in addition to stimulating the growth of many strains of the b. fragi ... | 1978 | 659574 |
| gas-lipuid chromatographic analysis of metabolic products in the identification of bacteroidaceae of clinical interest. | the acid end-products of 185 isolates from the family bacteroidaceae were separated and analysed by gas-liquid chromatography on broth cultures. different media were evaluated and definitive studies were performed in a fully supplemented complex medium. the limitations of this approach to the identification of a wide range of strains from various clinical sources were determined and the results were compared with those of a series of morphological, biochemical, tolerance and antibiotic-resistanc ... | 1978 | 660640 |
| bacteriologic culture results obtained before and after elective midtrimester urea abortion. | twenty patients undergoing elective midtrimester abortion by urea amnioinfusion had bacteriologic culture data obtained before and after the procedure. despite the presence of pathogens in the vagina and cervix prior to the procedure, only 20% of patients exhibited endometrial growth following abortion. factors that seem to favor such endometrial growth include increased injection-abortion intervals and the requirement for curettage to manage incomplete abortion. | 1978 | 668370 |
| [microbiological evaluation of cefoxitin, a new beta-lactamase resistant cephamycin antibiotic, compared to cephalothin, cephaloridine and cefazolin]. | cefoxitin (mefoxitin), cephaloridin, cephalothin and cefazolin were tested in vitro against 380 clinical isolates of staph. aureus and enterobacteriaceae using the tube dilution procedure. of the gramnegative microorganisms a selection of 150 strains was examined regarding susceptibility to the antibiotic combinations cefoxitin/gentamicin and cefoxitin/sisomicin in comparison to cephalothin/gentamicin and cephalothin/sisomicin. cefoxitin has a broad antimicrobial spectrum and a high beta-lactama ... | 1978 | 669547 |
| the role of bacteroides fragilis in abscesses of the central nervous system: implications for therapy. | 1978 | 670122 | |
| susceptibility of the bacteroides fragilis group of anaerobes to carbenicillin and ticarcillin. | 1978 | 670123 | |
| [bacteroides fragilis bacteremias: clinical and evolutive features about 33 cases (author's transl)]. | the frequency of non soil dwelling anaerobic infections is increasing. the authors report 33 cases of bacteroides fragilis bacteremias, and study the responsabilities of different factors of prognosis (especially age and underlying conditions). nitroimidazoles are very active against all bacteroides fragilis. this therapy is the drug of choice for such infections. | 1978 | 673771 |
| metronidazole treatment of liver abscess due to bacteroides fragilis. | a 67-year-old woman with a liver abscess due to bacteroides fragilis was treated with metronidazole 0.4 g orally every 8 h for 6 weeks. there was a rapid clinical improvement even though no surgical drainage was performed. by the indirect immunofluorescence technique using the patient's own strain as an antigen the antibody titer declined from 5120 to 80 in 6 months, suggesting eradication of the infecting agent. | 1978 | 675165 |
| [postoperative necrotizing enteritis with ristella septicemia. apropos of a case followed by recovery]. | 1978 | 677497 | |
| in vitro studies of piperacilin, a new semisynthetic penicillin. | piperacillin, a new semisynthetic penicillin, was compared with other semisynthetic penicillins, cephalosporins, and aminoglycosides by the agar dilution method against 3,600 isolates of facultative gram-negative bacilli, bacteroides fragilis, and enterococci. at 64 mug/ml, piperacillin inhibited 90% of the isolates in each group of organisms tested except for escherichia coli (83% inhibited by 64 mug/ml). compared with carbenicillin, piperacillin had a 16-fold increase in activity by weight aga ... | 1978 | 677861 |
| antibiotic therapy of endometritis following cesarean section. treatment successes and failures. | a prospective clinical and microbiologic study was carried out on 413 indigent patients undergoing cesarean section. operative site infection developed in 160 (38.5%). initial treatment with penicillin and kanamycin was successful in 125 of these 160 infections (78%). thirty-five patients (22%) failed to respond to penicillin and kanamycin and were treated with clindamycin or chloramphenicol. twenty-eight of the 35 responded promptly to the additional antibiotic therapy. the remaining 7 patients ... | 1978 | 683627 |
| bacteroides fragilis endocarditis, bacteremia and other infections treated with oral or intravenous metronidazole. | 1978 | 686012 | |
| in vitro activity and beta-lactamase stability of bl-s786 compared with those of other cephalosporins. | in vitro activity of bl-s786, a new parenterally semisynthetic cephalosporin, was investigated against 570 bacterial isolates. bl-s786 inhibited most escherichia coli, klebsiella pneumoniae, proteus mirabilis, and salmonella. it inhibited some enterobacter and indole-positive proteus, but it was less active against these later species than was cefamandole, cefuroxime, or cefoxitin. it was not active against serratia marcescens, pseudomonas aeruginosa, or bacteroides fragilis. bl-s786 was the lea ... | 1978 | 686701 |
| veterans administration cooperative study on bowel preparation for elective colorectal operations: impact of oral antibiotic regimen on colonic flora, wound irrigation cultures and bacteriology of septic complications. | a ten hospital cooperative study comparing prophylactic oral neomycin and erythromycin base versus placebo demonstrated clinical efficacy of the antibiotics in preventing septic complications following elective colon operations. the present report concerns microbiological studies accomplished during this trial. cultures of colon contents during surgery showed the antibiotic prep reduced concentrations of both aerobes and anaerobes by approximately 10(5) bacteria/ml. virtually all major bacterial ... | 1978 | 686893 |
| in vitro activity of tiamulin (81.723 hfu), a new pleuromulin derivative, against clinically significant anaerobes. | the susceptibility of more than 40 strains of gram-negative and gram-positive anaerobes to tiamulin (sandoz 81.723 hfu), a new pleuromulin (pleuromutilin) derivative, was determined by broth dilution and agar dilution tests. the influences of density of the inoculum upon mics was studied by a specially designed pour plate-technique. bacteroides fragilis, b. vulgatus, b. splanchnicus, b. oralis, b. asaccharolyticus, b. melaninogenicus, fusobacterium fusiforme (f. nucleatum), sphaerophorus necroph ... | 1978 | 690009 |
| the bacteriology and chemotherapy of otogenic cerebral abscesses. | 1978 | 690058 | |
| the distribution of bacteroides fragilis serotypes amongst clinical strains. | three hundred and twenty-two strains of bacteroides fragilis isolated from infected patients at three different hospitals were tested against 20 type specific b. fragilis antisera using the tube agglutination technique. of these strains 41.3% were assigned to a single o-serotype, a further 20.5% were agglutinated by several antisera and could not be classified and the remainder showed no reactions. three different serotypes were prevalent in the three hospitals and minor geographical variation w ... | 1978 | 690426 |
| the importance of c5 and the role of the alternative complement pathway in leukocyte chemotaxis induced in vivo and in vitro by bacteroides fragilis lipopolysaccharide. | chambers implanted subcutaneously in c5 normal (c5 n) and c5 deficient (c5 d) mice were used to examine the migration of polymorphonuclear leukocytes (pmns) into the wound chamber fluid in response to injected bacteroides fragilis lipopolysaccharide (lps). the difference in pmn migration was highly significant between the two mouse strains, the c5 d mice showing no initial, but a low, delayed migration. the results from the study indicated that chemotaxis plays a major role in the accumulation o ... | 1978 | 696326 |
| anaerobic and aerobic bacteriology in head and neck cancer surgery. | a prospective study of wound infections following major head and neck cancer surgery was undertaken to define a rational approach to trials of antibiotic prophylaxis and initial therapy of these infections. preoperative aerobic cultures were taken from the planned site of skin incision and from the oropharynx. both aerobic and anaerobic cultures were obtained from all wound infections. patients receiving prophylactic antibiotics were excluded from the study. the data indicate that preoperative c ... | 1978 | 697638 |
| participation of immunoglobulin and the alternative complement pathway in opsonization of bacteroides fragilis and bacteroides thetaiotaomicron. | studies were conducted to determine the requirements for immunoglobulin and complement for opsonization of bacteroides fragilis and bacteroides thetaiotaomicron. the ability of human sera depleted of immunoglobulin or complement components to promote phagocytosis and intracellular killing of the strains of bacteroides by human leukocytes was measured in vitro under anaerobic conditions. neither hypogammaglobulinemic sera nor pooled normal human serum (pnhs) heated at 56 c for 30 min supported ph ... | 1978 | 701850 |
| [asporogenic anaerobic bacterial cells isolated from extrahepatic abscesses and human breast tumor]. | 1978 | 704449 | |
| inactivation of metronidazole by anaerobic and aerobic bacteria. | the rate of inactivation of metronidazole in vitro was determined during the course of time-kill curves against anaerobic and aerobic bacteria in the stationary phase of growth. metronidazole at a concentration of 10 mug/ml, as measured by bioassay, was rapidly inactivated in broth culture by susceptible anaerobic bacteria (minimum bactericidal concentration </= 3 mug/ml), and this correlated closely with its bactericidal activity. in contrast, the drug was neither inactivated nor had any bacter ... | 1978 | 708015 |
| susceptibility of anaerobic bacteria to sulfamethoxazole/trimethoprim and routine susceptibility testing. | the minimal inhibitory concentrations (mics) of sulfamethoxazole and trimethoprim against 144 strains of obligately anaerobic bacteria were determined on diagnostic sensitivity test agar (oxoid) or in prereduced diagnostic sensitivity test broth, both supplemented with sodium pyruvate (1 mg/ml), hemin (5 mug/ml), and vitamin k(1) (1 mug/ml). fifty-eight percent of the strains were susceptible to sulfamethoxazole alone (mic </= 16 mug/ml), only 12% were susceptible to trimethoprim alone (mic </= ... | 1978 | 708016 |
| bacteroides fragilis meningitis in a neonate successfully treated with metronidazole. | 1978 | 712483 | |
| comparative susceptibilities of anaerobic bacteria to metronidazole, ornidazole, and sc-28538. | the susceptibilities of 284 anaerobic bacteria, including 55 strains of the bacteroides fragilis group, were determined by an agar dilution technique to metronidazole and two newer nitroimidazoles, ornidazole and sc-28538. all three agents showed marked in vitro activity against virtually all anaerobic bacteria tested. at concentrations </=1 mug/ml, sc-28538 was significantly more active than either metronidazole or ornidazole. at concentrations of >1 mug/ml, the activities of all three agents w ... | 1978 | 718156 |
| ticarcillin disodium in anaerobic infections. | twenty-five patients were treated with ticarcillin disodium, 18 of whom had anaerobic infections that included pleuropulmonary infections (seven), mandibular osteomyelitis (four), perirectal abscess (two), sepsis, primary site unknown (one), liver abscess (one), pelvic abscess (one), decubitus ulcer (one), and synergistic gangrene (one). seven had no anaerobic infections. three had anaerobic septicemia. culture results included anaerobes: peptococci (ten), peptostreptococci (ten), bacteroides fr ... | 1978 | 718311 |
| experimental bacteroides fragilis keratitis. | to determine the corneal pathogenicity of certain anaerobic bacteria, bacteroides fragilis keratitis was induced in rabbits by the intrastromal inoculation of 10' viable organisms. all eyes inoculated developed central abscesses within 24 hours. abscesses persisted and became vascularized in two of three eyes that were observed for two weeks, as demonstrated both clinically and histologically. eyes inoculated superficially with live organisms or intrastromally with solutions of dead organisms di ... | 1978 | 718520 |
| evaluation of microdilution trays (sensititre) for antimicrobial susceptibility testing of bacteroides fragilis. | microdilution trays (sensititre) for antimicrobial susceptibility testing of bacteroides fragilis has been compared for accuracy with the standard agar dilution method. the microtrays were found to be reliable for all antimicrobials tested (benzylpenicillin, clindamycin, doxycycline, chloramphenicol, fusidic acid, cefoxitin, and cephalotin) but not for metronidazole. | 1978 | 723780 |
| comparative in vitro activity of newer cephalosporins against anaerobic bacteria. | the in vitro susceptibilities of 408 recent clinical isolates of anaerobic bacteria against cefaclor, cephalexin, cephalothin, cefazolin, cefamandole, and cefoxitin were compared by an agar dilution technique. against gram-positive bacteria, especially peptococci, peptostreptococci, and propionibacteria, cephalexin and cefaclor were significantly less active than cephalothin (p < 0.05). cephalexin was also less active than cephalothin against clostridia and lactobacillus (p < 0.05). against gram ... | 1978 | 727759 |