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the role of the association in education for the profession. 1983264831
development of electrophysiological and biochemical membrane properties during differentiation of embryonic skeletal muscle in culture.newly fused chick myotubes undergo simultaneous and rapid changes in cell membrane properties during synchronous differentiation in culture. these changes are coordinately regulated and include increases in acetylcholine receptor, acetylcholinesterase, and resting potential, as well as the appearance of action potentials in discrete membrane areas upon stimulation. subsequently, the acetylcholine receptor reaches maximal levels, whereas the development of electrical properties is marked by a fur ...1983270755
yersiniosis in deer from the otago-southland region of new zealand.samples from 350 routine deer cases submitted to invermay animal health laboratory for diagnosis during 1979-1982 were examined specifically for the presence of yersinia sp. an analysis of 57 cases of yersiniosis due to yersinia pseudotuberculosis is made and two cases due to yersinia enterocolitica are described. the occurrence of cases appeared strongly correlated with periods of stress, predominantly in winter when cool wet conditions and lack of grazing combined to precipitate the disease. a ...198316030939
faecal survey of deer for yersinia pseudotuberculosis and salmonella sp.the results of a national survey of faeces from clinically normal deer for salmonella sp. and yersinia pseudotuberculosis are reported. five isolates of y. pseudotuberculosis and none of salmonella sp. were made from 3810 faeces representing 122 farms.198316030940
serotypes of yersinia pseudotuberculosis recovered from domestic livestock.the serological identity of 234 strains of yersinia pseudotuberculosis recovered from domestic animals and birds in new zealand was determined by slide agglutination test. thirty strains were also examined by tube agglutination test. the strains were isolated from cattle (56), sheep (8), deer (117), goats (13), pigs (7), rabbits (6), guinea pigs (5), and aviary species of birds (22). all strains were isolated from animals or birds which had died or shown signs of ill health and amongst which dia ...198416031006
yersinia pseudotuberculosis recovered from the faeces of clinically healthy deer. 198416031054
potential wildlife sources of yersinia pseudotuberculosis for farmed deer (cervus elaphus).during 1982 and 1983 15 serotype i, 6 serotype ii, 1 serotype iii and 3 untyped strains of yersinia pseudotuberculosis were isolated from 675 apparently normal small mammals and birds from the invermay farm and nearby rubbish tip with the following prevalence rates: feral cats 27.8%, norway rats 8.6%, mice 5.5%, hares 3.8% rabbits 1.9% ducks 5.3%, sparrows 2.3%, seagulls 2.3% and starlings 1.7%. for rabbits a significantly higher prevalence of infection was found in the autumn/winter period (4.8 ...198416031024
adverse reactions to methyldopa with particular reference to hypotension.of 26,294 consecutive patients monitored in a comprehensive drug surveillance program, 1067 (4 per cent) received methyldopa for treatment of hypertension. adverse reactions attributed to methyldopa were reported in 149 patients (14 per cent), the most frequent being hypotension. life-threatening adverse effects were reported in nine patients (6 per cent of reactors)--the major problems being hypotension associated in several patients with signs of cardiac or cerebral ischemia. hypotension attri ...1984263390
in vitro evaluation of opsonic and cellular granulocyte function by luminol-dependent chemiluminescence: utility in patients with severe neutropenia and cellular deficiency states.actively phagocytizing polymorphonuclear leukocytes (pmn) emit light or chemiluminescence (cl) which has been shown to be linked to the oxidative activity of the pmn. the measurement of cl has been demonstrated to be a useful tool for the in vitro assessment of intracellular and opsonophagocytic function of pmn. we have increased the sensitivity of the cl measurement by the addition of luminol to the in vitro reaction of pmn, bacteria, and serum. the presence of luminol, which can be oxidized to ...1984215546
tumor-associated humoral cytotoxicity in patients with acute myelogenous leukemia before and after chemotherapy.sera of eight unselected adult patients with acute myelogenous leukemia obtained before and after chemotherapy were repeatedly tested for specific complement-dependent cytotoxicity against autochthonous peripheral white blood cells from the acute leukemia stage and from the remission stage, respectively. complement-dependent cytotas demonstrated in all of the eight patients, while none of three patients' sera were reactive against white blood cells from the remission stage tested in parallel. th ...1984271142
a simple method of eminoplasty for correction of recurrent dislocation of the mandible.a simple surgical method of eminoplasty has been described that is rapid and has few complications. its value in the treatment of recurrent dislocation of the mandible is now well established. whether the procedure works by providing greater freedom of motion or by limitation is a moot point as the operation is highly successful.1984264267
leukocyte function after aortic valve replacement.leukocyte function was studied in patients with prosthetic heart valves by oxygen consumption measurements during phagocytosis of polystyrene latex particles. the consumption reflects the phagocytotic capacity of the cells. in 38 patients with starr-edwards aortic ball valves the mean oxygen consumption was 3.95 nanoatoms per minute per 10(6) leukocytes, as compared to 4.15 in 50 healthy subjects, the difference not being statistically significant. the number of leukocytes per ml. of blood and t ...1984263395
a comparison of serological techniques for plague surveillance.sera collected from 691 dogs and 231 rodents in south africa were tested in parallel by the passive haemagglutination (pha) and enzyme-linked immunosorbent assay (elisa) for antibodies to the fraction 1 antigen of the plague bacillus (yersinia pseudotuberculosis subsp. pestis). there was a high degree of correlation between the tests, both in over-all numbers positive and in serum titres. 42 dog sera were positive by pha and 41 by elisa, 40 sera being positive by both tests. however, using elisa ...19846533848
characterization and pathogenicity of yersinia pseudotuberculosis isolated from swine and other animals.yersinia pseudotuberculosis serogroup iii is most frequently detected in healthy pigs. y. pseudotuberculosis strains were divided into two biogroups on the basis of their fermentation of melibiose. melibiose-fermenting strains were distributed in all the hosts and serogroups examined. melibiose-nonfermenting strains were limited to serogroup iii isolated from healthy pigs. autoagglutination and calcium dependency were not related to fermentation of melibiose. melibiose-fermenting strains seem to ...19846470095
y. pseudotuberculosis infection. 19846366491
[electron microscopic study of the interaction of yersinia pseudotuberculosis with macrophages and hela cells].the comparative electron-microscopic study of early stages of the interaction of y. pseudotuberculosis virulent strain (no. 282) with "professional" (macrophages) and "nonprofessional" (hela cells) phagocytes has been carried out. the character of the intimate mechanism of this interaction has been found to be essentially different. the common feature for both systems is the adsorption of bacteria and their penetration into cells due to phagocytosis. but the subsequent fate of y. pseudotuberculo ...19846485665
[joint manifestations and yersinia pseudotuberculosis. correlation between the clinical and biological aspects].the authors attempt to evaluate the specificity of yersinia pseudotuberculosis (ypt) serology on the basis of 94 new cases of aseptic joint lesions associated with serology considered to be positive. the cases selected from the file of the international reference centre for yersinioses (institut pasteur, paris, prof. h.h. mollaret), were divided into 4 groups: group a (n = 46) where the joint lesions had no proven aetiology and the positive ypt serology makes the diagnosis of yersiniosis possibl ...19846333711
yersinia enterocolitica 03 findings on porcine tongues in comparison with yersiniosis incidence in man in czechoslovakia.positive isolations of yersinia obtained in repeated bacteriological examinations of porcine tongues at three slaughter-houses in prague and a single examination at the slaughter-house at kladno were compared with notified yersiniosis morbidity. the incidence of illnesses caused by y. enterocolitica 03 does not exceed values of 4.5/100,000 and 3.5/100,000 population in the czech and slovak socialist republics, respectively, and is equal to a sixtieth part of the notified shigellosis and salmonel ...19846491274
[a child case of yersinia pseudotuberculosis septicemia]. 19846434658
[structure of o-specific polysaccharide isolated from the yersinia pseudotuberculosis serotype 1a lipopolysaccharide].an o-specific polysaccharide from the lipopolysaccharide yersinia pseudotuberculosis 1a serovar has been isolated and characterized. this compound was shown to contain residues of paratose, 6-deoxy-d-manno-heptose, d-galactose and 2-amino-2-deoxy-d-glucose in equimolar ratios. using methylation studies, partial acid hydrolysis and 13c nmr spectroscopy, the following structure was proposed for the repeating unit of the o-specific polysaccharide: (formula: see text).19846207836
incidence of yersinia organism in hare in the northwestern region of okayama prefecture. 19846398397
lack of correlation between the presence of plasmids and fimbriae in yersinia enterocolitica and yersinia pseudotuberculosis.thirty-nine strains of yersinia enterocolitica and 10 strains of yersinia pseudotuberculosis were studied for the presence of fimbriae, plasmids and two plasmid associated phenotypic expressions, autoagglutination and ca2+ dependent growth at 37 degrees c. all of the strains studied became fimbriated, which was confirmed by electron microscopy and haemagglutination tests. fimbriation was not correlated with the presence or absence of plasmids.19846146593
in vivo comparison of avirulent vwa- and pgm- or pstr phenotypes of yersiniae.the abilities of yersinia pestis to undergo restriction in ca2+-deficient medium with concomitant production of v and w antigens (vwa+) and to absorb exogenous pigments (pgm+) are established virulence factors. mutation of y. pestis to pgm- is known to promote resistance to pesticin (pstr) and reduced lethality by peripheral routes of injection. vwa+ pgm- isolates of y. pestis were shown in this study to retain virulence in mice when injected intravenously. although pgm- in appearance, wild-type ...19846365786
[laboratory diagnosis of pseudotuberculosis]. 19846367091
roles of v antigen in promoting virulence and immunity in yersiniae.it is established that yersiniae harboring an approximately 45-megadalton vwa-plasmid can produce v and w antigens (vwa+), and that sera containing anti-v provides passive protection to mice against yersinia pestis. this observation was extended by the use of monospecific anti-v prepared by injecting rabbits with partially purified v, absorption of antisera with a vwa- extract, and then separation of gamma-globulin by traditional processes of fractionation or by affinity chromatography. these pr ...19846381597
[gougerot-sjögren's syndrome. clinical and biological correlations with the serology of yersinia infections].an unusual case of sjögren's syndrome (ss) induced or revealed by a yersinia pseudotuberculosis serotype iv infection has prompted the authors to undertake a retrospective study of 32 patients with that syndrome. high titers of antibodies to y. pseudotuberculosis serotype iv (greater than 1/200 th) were found in 4 patients with primary sjögren's syndrome and sharp's syndrome. seven other patients (5 with primary sjögren's syndrome, 1 with systemic lupus erythematosus and 1 with sharp's syndrome) ...19846231628
[invasiveness characteristics of the causative agent of pseudotuberculosis].the comparative characteristics of the invasiveness of y. pseudotuberculosis, the most important element of its pathogenicity, is given on the basis of the results obtained in testing 57 y. pseudotuberculosis strains and 23 y. enterocolitica strains, all of them recently isolated, on experimental models (the monolayer cultures of hep-2 cells, the enteral inoculation of mice and guinea pigs, the keratoconjunctival test). the invasiveness of y. pseudotuberculosis has been shown to be manifested im ...19846377777
characterization of common virulence plasmids in yersinia species and their role in the expression of outer membrane proteins.the virulence plasmids pyv019, pyv8081, and pib1 from yersinia pestis, yersinia enterocolitica, and yersinia pseudotuberculosis, respectively, were characterized by restriction endonuclease analysis. the three plasmids exhibited a region of common dna previously shown to encode determinants which confer ca2+ dependence. the plasmids from y. pestis and y. pseudotuberculosis were similar throughout their genomes. in contrast, a region of the plasmid from y. enterocolitica which contained an origin ...19846317562
molecular cloning of the temperature-inducible outer membrane protein 1 of yersinia pseudotuberculosis.when yersinia pseudotuberculosis is shifted from growth at 26 degrees c to growth at 37 degrees c, the synthesis of a plasmid-associated outer membrane protein, protein 1, is induced (bölin et al., infect. immun. 37:506-512). the structural gene of this protein was found to be located on the virulence plasmid pib1 of y. pseudotuberculosis. one cosmid hybrid plasmid pbw8 was studied which carried a region of the virulence plasmid. this hybrid plasmid expressed in escherichia coli k-12 a novel tem ...19846317574
[adhesion of yersinia pseudotuberculosis serotype iii].the use of the erythrocyte agglutination test for characterizing the properties of y. pseudotuberculosis led to the detection of a highly adhesive strain belonging to serotype iii and capable of forming pili at 37 degrees c. the adhesion of the cells provided with pili was completely inhibited by the mixture of gangliosides, specific antibodies, and the preliminary treatment of erythrocytes with neuraminidases sharply enhanced the effectiveness of adhesion. the adhesion pili consisted of protein ...19846151768
yersinia pseudotuberculosis septicaemia in thalassaemia major. 19846140358
[study of a lipid a-protein complex from yersinia pseudotuberculosis endotoxin].mild acid hydrolysis of endotoxin of yersinia pseudotuberculosis afforded a lipid a--protein complex composed of amino acids and all characteristic components of lipid a: glucosamine, dodecanoic, 3-hydroxytetradecanoic acids and phosphorus in a molar ratio of 2 : 1,5 : 2,8 : 1,7, respectively. the protein component of the complex was shown by gel electrophoresis in the presence of sodium dodecylsulphate to consist of two polypeptides with apparent molecular weights of 12000 and 8000. the lipid a ...19846487389
community outbreak of yersinia pseudotuberculosis.an outbreak of yersinia pseudotuberculosis in kurashiki, japan is described. this is the first conclusive report of a community outbreak of this microorganism. a total of 535 pupils, five teachers, and one food attendant contracted the organism. causative organisms were detected in 19 out of 30 patients. all isolated strains belonged to serotype va. out of 653 sera of the pupils, 488 showed elevated agglutinin titers ranging from 1:80 to 1:1,280 or more within a period of 3 months.19846503742
ovine abortion and stillbirth due to purulent placentitis caused by yersinia pseudotuberculosis.yersinia pseudotuberculosis was isolated from an aborted placenta and stillborn lamb from a sheep flock having multiple abortions. given intravenously, it caused elevated body temperatures and purulent placentitis in eight of nine ewes. two ewes died following infection at 2.5 months of gestation. two ewes infected at 3.5 months gestation aborted; three infected at four months gave birth to weak, premature, or moribund lambs. one ewe infected at 4.5 months gave birth to a healthy lamb. one lamb ...19846516181
d-3-dodecanoyltetradecanoic acid as a constituent of lipid a from the lipopolysaccharide of yersinia pseudotuberculosis.d-3-dodecanoyltetradecanoic acid has been separated from the lipid a of yersinia pseudotuberculosis and its structure has been established by chromato-mass-spectrometry and 13c nmr spectroscopy, by comparison with authentic samples.19846547679
[hepatitis caused by yersinia enterocolitica in children]. 19846371698
[sedimentation properties of a lipopolysaccharide-protein complex from yersinia pseudotuberculosis].it was shown that in water media lipopolysaccharide-protein complex (lpspc-) forms compact units with molecular weight 1.29 x 10(6) inclined to self-association. disaggregation of lpspc to subunits with molecular weight 7 x 10(4) under the action of the detergent and edta reveals the substantial role of hydrophobic interaction of ions of divalent metals in the formation of high molecular weight aggregates.19846394052
[granulomatous appendicitis]. 19846373517
growth of yersinia pseudotuberculosis in mouse spleen despite loss of a virulence plasmid of mol. wt 47 x 10(6).a highly virulent strain of yersinia pseudotuberculosis (ld50 c. 10(2) bacteria/mouse) harboured two plasmids with mol. wt of 47 x 10(6) and 61 x 10(6). the role of these plasmids in virulence was studied in mice with derived strains cured of plasmids. it was confirmed that the plasmid of mol. wt 47 x 10(6) played a major function in virulence. this was shown both by the increase of the ld50 and the lower rate of multiplication in the spleen obtained with strains cured of the plasmid of mol. wt ...19846389874
an outbreak of yersinia pseudotuberculosis infection.nineteen patients were involved in an outbreak of infection caused by yersinia pseudotuberculosis serotype 3. no epidemics attributable to this microorganism have been previously reported; the most extensive known cluster of cases involved four children in one family and their pet dog. the key finding in the outbreak described in the present study was the bacteriologic identification of serotype 3 in stool specimens from patients with clinically typical yersiniosis. twelve cases were identified ...19846699434
virulence plasmid-associated autoagglutination in yersinia spp.the autoagglutination of yersinia enterocolitica was dependent on the presence of the virulence plasmid and on the active growth of bacteria in tissue culture media at 37 degrees c. cultures with a high initial concentration of bacteria failed to autoagglutinate , indicating that synthesis of new virulence plasmid-associated surface factors was essential for autoagglutination. the synthesis of a plasmid-encoded polypeptide (molecular weight, 240,000), designated p1, that could be dissociated und ...19846725209
isolation of yersinia pseudotuberculosis from bovine calves with enteric disorders. 19846727718
a case of yersinia pseudotuberculosis septicemia accompanied by a large abdominal tumor.a 2-year-old girl with yersinia pseudotuberculosis septicemia had a large abdominal mass that had to be differentiated from malignant tumor. the mass disappeared rapidly with antibiotic therapy and was defined to be a cluster of enlarged ileocecal lymph nodes by the clinical course and the findings at ultrasonic examination and gallium scintigraphy.19846362954
[pathomorphology of experimental pseudotuberculous (yersinia) arthritis].experimental pseudotuberculosis arthritis was reproduced by means of antigenic irritation of the knee joint in the presence of specific sensibilization. pathomorphology is characteristic of the acute exudative-proliferative synovitis and periarthritis. the results obtained allow one to draw the conclusion on the infectious-allergic genesis of the joint involvement in pseudotuberculosis. the stages in the allergic responses of the synovial membrane with subsequent development of early and late im ...19846380461
[an abdominal form of pseudotuberculosis simulating acute appendicitis]. 19846388120
prospective systematic study of yersinia spp. in dogs.a total of 93 yersinia spp. were isolated from 68 of 252 dogs in shimane prefecture, japan. the yersinia spp. were 70 yersinia enterocolitica isolates from 50 dogs, 2 yersinia frederiksenii isolates from 2 dogs, 5 yersinia intermedia isolates from 5 dogs, and 16 yersinia pseudotuberculosis isolates from 16 dogs. fifteen of 70 y. enterocolitica isolates belonged to biotype 4 serotype o3 phagotype 8 (6 isolates), biotype 4 (maltose negative) serotype o3 phagotype 8 (4 isolates), biotype 3 (voges-p ...19846736224
distinctive electrophoretic and isoelectric focusing patterns of esterases from yersinia enterocolitica and yersinia pseudotuberculosis.esterases of 53 strains of yersinia enterocolitica sensu stricto, including five previously defined biotypes, and 30 strains of yersinia pseudotuberculosis were analysed by horizontal polyacrylamide-agarose gel electrophoresis and by isoelectrofocusing in thin-layer polyacrylamide gel. esterase bands were defined by their range of activity towards several synthetic substrates, their resistance to heat and to di-isopropyl fluorophosphate. the two species were characterized by distinct electrophor ...19846481338
[severe forms of yersinia pseudotuberculosis infection]. 19846397236
patients with active crohn's disease have elevated serum antibodies to antigens of seven enteric bacterial pathogens.a variety of bacterial pathogens including campylobacter, yersinia, listeria, brucella, and mycobacteria have been suggested as potential etiologic agents for crohn's disease. to assess the role of these organisms we studied responses to eight antigens in sera from patients with active crohn's disease and healthy age- and sex-matched controls. in complement-fixation assays, the sera from the crohn's disease patients had enhanced reactivity compared with the control sera to all seven orally inges ...19846468876
[inflammatory cancer of the breast. assessment after 6 years of 16 patients treated by primary immunochemotherapy].sixteen patients with clinical primary inflammatory carcinoma of the breast were treated with initial immunochemotherapy from september 1974 to may 1977. this chemotherapy was an association of adriamycin, vincristine, fluorouracil, methotrexate, and melphalan. thermographic cooling was taken as the criterion of operability. chemotherapy was resumed after surgery up to a total of ten periods, and followed by a minimum one year chemotherapy. i-bcg-f pasteur was used as immunotherapy and associate ...19853897362
the effect of heat shock on the cell cycle regulation of tubulin expression in physarum polycephalum.in the myxomycete physarum polycephalum, tubulin synthesis is subject to mitotic cycle control. virtually all tubulin synthesis is limited to a 2-h period immediately preceding mitosis, and the peak of tubulin protein synthesis is accompanied by a parallel increase in the level of tubulin mrna. the mechanism by which the accumulation of tubulin mrna is turned on and off is not clear. to probe the relationship between tubulin regulation and cell cycle controls, we have used heat shocks to delay m ...19853968184
glycine antagonism by ru 5135.in the spinal cord of the pentobarbitone-anaesthetised cat, microelectrophoretic ru 5135, a steroid derivative, was a potent strychnine-like glycine antagonist, having less effect on the inhibition by gaba of neuronal firing.19854007055
the corneal endothelial cell interface.the apical edges of corneal endothelial cells have been separated along lines forming a crisscross pattern, by the help of a special method of preparation. the visualization by sem of the lateral faces of the cells is thereby made possible. the separation leads to the formation of thin strands spanning the gap between the apical edges of adjoining cells. they are formed by stretching of the normal apical flaps. this stretching demonstrates that the main intercellular adherence is located at the ...19853993338
expression of the temperature-inducible outer membrane proteins of yersiniae.the expression of the temperature-inducible plasmid-coded outer membrane proteins (yops) of yersinia pseudotuberculosis was studied. these proteins were not recovered in the outer membrane fraction when the strain was grown in minimal medium at 37 degrees c, but they were expressed under these conditions. a strict correlation was found between ca2+ dependency in the virulent strain, ypiii(pib1), and ability to express yops. ca2+-independent plasmid mutants or rna-polymerase mutants harboring the ...19853980086
injury to the isolated, perfused lung by exposure in vitro to monocrotaline pyrrole.monocrotaline pyrrole (mctp) is a reactive metabolite of the pyrrolizidine alkaloid monocrotaline. it causes pulmonary lesions associated with pulmonary hypertension and right ventricular hypertrophy. conditions of exposure to mctp that result in early lung injury were examined in isolated rat lungs perfused with buffered medium containing 4% bovine serum albumin. when a high, acutely lethal dose (8.1 mg) of chemically synthesized mctp was added to the 50-ml perfusion medium reservoir, no effect ...19854043006
phosphatidylinositol-specific phospholipase c from bovine blood platelets. inhibition by calmodulin-inhibitors--activation by atp and adp.the phospholipase c-activity in crude extracts of bovine blood platelets is strongly inhibited by the calmodulin-inhibitors fluphenazine and calmidazolium in the mm range, and activated by atp and adp, but not by amp. the activating effect is also shown by the nonhydrolysable atp- and adp-analogs alpha,beta- and beta,gamma-methyleneadenosine 5'-triphosphate and alpha,beta-methyleneadenosine 5'-diphosphate, thus indicating that it is an allosteric effect. the stimulation of the phospholipase c-ac ...19853993181
[yersinia pseudotuberculosis infections. etiologic clarification using fecal cultures].isolation of the causative organism in stool proved the aetiology of yersinia pseudotuberculosis in two patients. in a 12-year-old boy the clinical picture was of appendicitis. after appendicectomy the histological findings provided the diagnosis. the second patient, a 2-year-old girl, had protracted enteritis, completely cured by a course of cotrimoxazole. culturing of y. pseudotuberculosis from stool has previously been very rare. but new methods of culturing and other recent advances provide ...19853896724
protection against yersinia infection induced by non-virulence-plasmid-encoded antigens.specific immunity against yersinia was induced by plasmid-encoded antigens not associated with virulence. mice were immunised with viable bacteria from a virulence-plasmid-cured strain of y. pseudotuberculosis. this antigenic stimulation generated specific protection against virulence-plasmid-harbouring strains of y. pseudotuberculosis and y. pestis, demonstrating that protection can be generated by organisms lacking plasmid-encoded virulence antigens.19853900406
[state of the kidneys in patients with pseudotuberculosis]. 19853900559
[pseudotuberculosis in young children]. 19853916347
regulation of cardiac vulnerability by the cerebral defense system.psychosocial stressors are risk factors for sudden cardiac death. a theoretical model of the brain mechanism that links defined environmental events (stressors) to cardiac vulnerability (initiation of ventricular fibrillation) has been developed. in the model, a stressor event evokes a set of electrochemical responses in the frontal cortex. depending on the state of acquisition of these electrochemical responses to the stressor, activity will or will not be initiated in the frontocortical-brains ...19853923079
evaluation of the micro-id system for the identification of yersinia pestis.one hundred isolates of yersinia pestis identified by conventional means were tested by the micro-id system to assess its reliability for distinguishing y. pestis from other members of the family enterobacteriaceae. the micro-id system gave y. pestis as a choice for the identification of 89 of these cultures, although not always as the first choice. most nitrate-negative strains of y. pestis keyed out with yersinia pseudotuberculosis as first choice and y. pestis as second or fourth choice.19853980695
metastatic nontraumatic clostridium septicum osteomyelitis.nontraumatic clostridial infections are rare, but need to be diagnosed and treated early or high morbidity and mortality rates result. we believe that this is the first reported case of metastatic nontraumatic clostridium septicum osteomyelitis. early treatment with surgical debridement and parenteral antibiotics without hyperbaric oxygen was used. an associated occult rectal malignancy was discovered and treated.19853980945
problems concerning the usefulness of adjustment of urinary cadmium for creatinine and specific gravity.a previous study concluded that there are some doubts as to the validity of creatinine as a parameter for adjusting the values of biological indicators determined on spot samples of urine, since it is subject to marked inter- and intraindividual variations. furthermore, since there was only a moderate correlation between creatinine levels and specific density, it can be assumed that these two parameters cannot be used indifferently for adjustment. nevertheless, it seemed advisable to verify whet ...19853988354
plasmid dna relatedness among different serogroups of yersinia pseudotuberculosis.thirteen different serogroup strains of yersinia pseudotuberculosis and two strains of yersinia enterocolitica o:3 were examined for the presence of plasmids and plasmid-mediated properties, calcium growth dependency, and autoagglutination. two y. enterocolitica strains and eight serogroup (ia, iia, iic, iii, iva, vb, vi, and viii) strains, except for five serogroups (ib, iib, ivb, va, and vii), of y. pseudotuberculosis harbored plasmids ranging in molecular size from 27 to 115 kilobases. filter ...19853988910
[diseases of nutria and their therapeutic potential].the article reports important diseases and different farming techniques of nutria. e. coli and salmonella infections are the most important bacterial diseases. coccidiosis and strongyloidosis are frequently observed in nutria farms. differentiated prophylactic treatment and hygiene are necessary for optimal breeding conditions.19853895571
epidemiological study of yersinia enterocolitica and yersinia pseudotuberculosis infections in shimane prefecture, japan.in shimane prefecture, japan, 175 yersinia enterocolitica isolates from 6,479 stools and 347 appendixes of patients were separated into biotype 3b (vp-, sorbose-, inositol-) serotype o3 phage type ii (22 isolates); biotype 4 (84 isolates), biotype 4 (ornithine-) (16 isolates) and biotype 4 (maltose-) (9 isolates) of serotype o3 phage type viii, biotype 2 serotype o9 (1 isolate) and biotype 1 (43 isolates). this may be the first documentation of isolation of y. enterocolitica biotype 3b serotype ...19853895776
31p-saturation-transfer nuclear-magnetic-resonance measurements of phosphocreatine turnover in guinea-pig brain slices.the technique of 31p saturation-transfer n.m.r. was used to determine the forward and the reverse rate constants of creatine phosphotransferase in superfused guinea-pig cerebral tissues in vitro. the calculated forward rate constant of 0.22 +/- 0.03s-1 compared well with a previously reported value for rat brain in vivo [shoubridge, briggs & radda (1982) febs lett. 140, 288-292]. the reverse rate constant was found to be 0.55 +/- 0.10s-1. 3. by using concentrations of atp and phosphocreatine est ...19854004799
role of virulence-associated plasmid in the uptake and killing of yersinia pseudotuberculosis by resident macrophages.resistance to phagocytosis of yersinia pseudotuberculosis by mouse resident macrophages was investigated using a highly virulent plasmid-bearing strain and its low-virulent plasmid-free derivative. it was found that plasmid-bearing and plasmid-less bacteria did not resist the ingestion step nor inhibit the oxidative burst and phagolysosomal fusion in the peritoneal macrophages. these in vitro data were further confirmed by the study of bacterial survival in infected mice. bacteria from plasmid-b ...19853833056
characteristics of primary isolates of alveolar type ii cells from neonatal rats.alveolar type ii cells from 6-day-old rat pups were obtained at approximately 90% purity, as judged by light and electron microscopy. within 48-72 h in culture, the cells formed a monolayer with tight junctions typical of epithelial cells. type ii cells aggregated into raised domelike areas, which when sectioned showed alveolarlike structures comprised of type ii cells. after 3 days in culture these structures showed abundant lamellar body secretion. phospholipid profiles were characteristic of ...19853840085
temperature-inducible surface fibrillae associated with the virulence plasmid of yersinia enterocolitica and yersinia pseudotuberculosis.when cultivated at 37 degrees c in static broth, human clinical isolates of yersinia enterocolitica (serogroups o:3, o:8, and o:9) and yersinia pseudotuberculosis (serogroup o:iii) produced numerous nonflagellar surface appendages, which appeared as a lawn of fine fibrillae, each having a diameter of 1.5 to 2.0 nm and a length of 50 to 70 nm. cultivation at 22 degrees c resulted in complete disappearance of the fibrillae. the phenotypic expression of these appendages was correlated with the pres ...19853881355
yersinia colitis associated with crohn's disease.a previously healthy patient developed serologically-proven yersinia pseudotuberculosis enterocolitis and made a complete recovery. over a year later, further gastrointestinal symptoms developed and crohn's disease was diagnosed. the possible relevance to the aetiology of crohn's disease is discussed.19853885200
schistosoma mansoni: an ultrastructural examination of skin migration in the hamster cheek pouch.the hamster cheek pouch has been used to investigate the skin migration of schistosomula at the ultrastructural level. parasites have been observed up to 72 h post-infection. despite rapidly reaching the epidermal basement membrane schistosomula remain in an epidermal location for at least 40 h post-infection, by which time the acetabular glands and their ducts have been lost and the transformation from cercaria to schistosomulum completed. entry into the dermis and exit from the skin via the bl ...19854034241
[synthesis of lipid a analogs. obtaining conjugates of 6-phosphate 2-desoxy-2-(3-hydroxymyristoyl)amino-d-glucose with polymer carriers and their immunological properties].the derivatives of 2-acylamino-6-o-(2-aminoethyl) phosphono-3-deoxy-d-glucose acylated with acetic or d,l-3-hydroxytetradecanoic acid were obtained, and their 31p-and 13c-nmr spectra investigated. these haptens were bound with a polysaccharide (ficoll) or proteins (albumins, bovine gamma-globulin). the protein conjugates were immunogenic in rabbits, specific antibodies against the hapten being revealed by two immunochemical methods. as shown by the enzyme-linked immunoadsorbent assay, the specif ...19853899123
[interaction of yersinia pseudotuberculosis with the epithelium of the small intestine in experimental infection].some data showing specific ways of interaction of yersinia pseudotuberculosis with the epithelium of the small intestinal mucosa have been received for the first time by using light microscopy of semithin sections. comparative study of the lesion of the epithelium of different parts of rabbit small intestine by oral inoculation with yersinia tuberculosis has expanded the ideas of the infection entry. it has been established for the first time that the most intensive penetration of the microorgan ...19853893561
[role of biologically active substances in the pathogenesis of the allergic component of pseudotuberculosis in children]. 19853900918
the resistance to anti-microbial agents of bacteria isolated from pathological conditions of birds in victoria, 1978 to 1983.the resistance to anti-microbial agents of bacteria isolated from pathological conditions of birds in victoria, 1978 to 1983, was determined for isolates of escherichia coli, salmonella species, staphylococcus aureus, pasteurella multocida, p. anatipestifer, yersinia pseudotuberculosis and haemophilus paragallinarum. the isolates of e. coli had a high prevalence of resistance to tetracycline and sulphonamides, and a lower prevalence of resistance to furazolidone and sulphamethoxazole-trimethopri ...19853914884
[the incidence and seasonal dynamics of yersinioses (y. pseudotuberculosis, y. enterocolitica), staphylococcoses and pasteurelloses in hares from 1976 to 1982].in the years 1976-1982, 2071 dead hares from 64 districts of the czech socialist republic were examined. the diseases under study killed 400 hares (19.3%). pseudotuberculosis which killed 210 hares (10.14%) from 46 districts of the czech socialist republic (71.9%) is considered as the most important hare population regulator. the highest occurrence of diseases was recorded in 1978. pseudotuberculosis was of seasonal nature with the highest incidence in november and december. the second most wide ...19853927559
changes in the sedimentation properties of cytosolic androgen receptors associated with activation in vitro and in vivo.in cell-free systems androgen receptor (ar) labeled with (3h)dht at 0 degrees c in the presence of 50mm molybdate remains unactivated (less than 3% binding to nuclei) and untransformed (7-8s on sucrose density gradients containing 0.4m kcl and 50mm molybdate). in the absence of molybdate, however, these complexes undergo activation and transformation even at 0 degrees c, albeit, very slowly. incubation of unactivated, untransformed ar complexes at 18 degrees c, or at 0 degrees c in the presence ...19853842022
the state of and prospects for molecular genetics in burkitt's lymphoma. 19854065951
[study of the aggregation of membrane proteins of erythrocyte ghosts using sds-paag electrophoresis].using the method of electrophoresis in sds-paag the authors showed a diminution of proteins of bands i + ii (spectrins) and iii (major integral protein) after irradiation of erythrocyte ghosts with doses of 50 to 1000 gy. we failed to ascertain that radiation-induced lipid peroxidation is involved into membrane protein aggregation. among the radiolysis products, oh-radicals were shown to contribute markedly to the radiation effect observed.19854070566
direct isolation of yersinia enterocolitica and yersinia pseudotuberculosis from meat.studies were done to determine the usefulness of dilute alkali (koh) treatment of meat samples for direct isolation of yersinia enterocolitica and yersinia pseudotuberculosis, without enrichment. virulent y. enterocolitica and y. pseudotuberculosis in pork contaminated with 10(2), 10(3), and 10(4) cells per g survived the direct koh treatment and were never recovered by using koh postenrichment treatment. from 6 (4.8%) of 125 samples of retail ground pork, four biotype 4 serotype o3 and one biot ...19854073898
reactivities of neoplastic t cells to human autoantibody and monoclonal antibodies. 19853873778
influence of the thromboxane antagonist bm 13.177 on the arachidonic acid-induced increase in pulmonary vascular resistance and permeability in rabbit lungs.in blood-free perfused isolated rabbit lungs increased availability of free arachidonic acid (aa), whether exogenously applied or released from the endogenous membrane phospholipid pool after different stimuli, causes an acute pulmonary artery pressor response and an increase in vascular permeability. previous experiments suggested that the vasoconstriction is caused primarily by the cyclooxygenase product thromboxane (tx) a2, whereas an increase in the capillary filtration coefficient must be a ...19853937288
gonadotropin-releasing hormone within the organum vasculosum lamina terminalis in the ovariectomized, estrogen/progesterone-treated rat: a quantitative immunocytochemical study using image analysis.no specific function has been ascribed to the high gonadotropin-releasing hormone (gnrh) content of the organum vasculosum lamina terminalis (ovlt). the objective of this study was to determine whether levels of gnrh within the ovlt are altered during cyclic gonadotropin secretion. gnrh levels were determined at various times during an estrogen/progesterone (e/p)-induced lh surge. groups of e/p and sesame oil-treated animals were decapitated at 12.00 h, 14.00 h, 16.00 h, 18.00 h, and 22.00 h fol ...19853896396
lutzomyia gasparviannai martins, godoy & silva, 1962, probable vector of leishmania mexicana ssp. in viana municipality, espírito santo state, brazil. 19853837837
prevention of neonatal hyperbilirubinaemia in non-human primates by zn-protoporphyrin.non-human primates were used as a model of human neonatal hyperbilirubinaemia and its chemotherapeutic suppression. high levels of haem oxygenase activity were detected in the liver and the spleen of neonatal rhesus (macaca mulatta) and cynomolgus (macaca irus) monkeys. when 1-day-old neonatal animals were given a single injection of zn-protoporphyrin (40 mumol/kg, subcutaneously), serum bilirubin levels declined to nearly normal adult levels within 24 h and remained suppressed throughout the po ...19853838470
quantitative assessment of the role of o6-methylguanine in the initiation of carcinogenesis by methylating agents.induction of transformation, cell lethality, and dna lesions were quantitatively compared in syrian hamster embryo cells (hec) treated with three different methylating agents: n-methyl-n'-nitro-n-nitrosoguanidine (mnng), n-methyl-n-nitrosourea (mnu), or methyl methanesulfonate (mms). each induced transformation in a dose-dependent manner. on a molar basis, mnng was approximately equal to 100- and 500-fold more effective than mnu and mms, respectively. for each carcinogen the induction and repair ...19853855560
synthesis in e. coli of alpha 1-antitrypsin variants of therapeutic potential for emphysema and thrombosis.the primary function of alpha 1-antitrypsin (alpha 1-at), an antiprotease produced by the liver, is the inhibition of neutrophil elastase, a protease capable of hydrolysing most connective tissue components. the importance of alpha 1-at is demonstrated by the high incidence of early-onset emphysema in individuals with hereditary alpha 1-at deficiency (type pizz), in whom serum levels of alpha 1-at are 10-20% of normal. oxidants in tobacco smoke can inactivate alpha 1-at in vitro, and studies hav ...19853880873
[rare forms of yersinia infections in adults]. 19853887018
repair of dna single-strand breaks in x-irradiated yeast. ii. kinetics of repair as measured by the dna-unwinding method.the kinetics of disappearance of single-strand breaks (ssb) from the dna of x-irradiated stationary yeast cells under liquid-holding conditions was found to proceed in a dose-independent manner up to a dose of at least 2400 gy, and was found to be complete after incubation of cells for 1 h. this was deduced from data for a yeast wild-type (wt) haploid and diploid strain as well as for rad52 haploid cells defective in dna double-strand break (dsb) repair. in all cases an initial fast repair compo ...19853889609
[effect of lipopolysaccharide of the pseudotuberculosis bacterium on the functional activity of macrophages].study of the effect of lipopolysaccharide (lps) of y. pseudotuberculosis on the culture of peritoneal macrophages of guinea pigs has established that in concentrations of 1-10 micrograms/ml lps stimulated the absorption and digestive activity of the macrophages. in concentrations of 50-100 micrograms/ml it had a cytotoxic effect on the cell elements and inhibited their phagocytic function. the study of the lps effect on absorption and liberation of 14c-labeled bacteria of y. pseudotuberculosis s ...19853890720
[epidemiological analysis of the incidence of infectious diseases]. 19853892887
[psychrophilic properties of pathogenic microorganisms and their epidemiological and pathogenetic significance]. 19853883673
transfer of the virulence plasmid of yersinia pestis to yersinia pseudotuberculosis.transposon tn5 insertion derivatives of the virulence plasmid pyv019 of yersinia pestis were transferred by p1 transduction into a plasmid-free strain of y. pseudotuberculosis. one of these plasmid derivatives conferred virulence upon the y. pseudotuberculosis strain. this strain had the ability to express temperature-inducible plasmid-coded outer membrane proteins and was also found to be ca2+ dependent.19853884511
[yersinia pseudotuberculosis infection]. 19853897661
[synthesis of vitamin d in the skin]. 19853898049
splenectomy in experimental pancreas transplantation. 19853904093
[taxonomy of the causative agents of plague and pseudotuberculosis]. 19853904284
a case of infection of yersinia pseudotuberculosis associated with complement abnormalities. 19853905549
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