Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| antimicrobial resistance of shigellae isolated in michigan. | patterns of antimicrobial resistance were studied for 213 strains of shigellae isolated in rural and urban areas of michigan by quantitative techniques: 66% of these organisms were resistant to ampicillin, tetracycline, cephalexin, or chloramphenicol or had multiple resistance to various combinations of these antibiotics. the incidence of resistant organisms was higher in the detroit-wayne county area, which is the most urban part of the state. nalidixic acid and oxolinic acid were noted to be q ... | 1975 | 1089819 |
| observations on the serologic changes in the recombinants in shigella flexneri serotype 4a. | studies on the antigenic composition of 84 diagnostic strains of s. flexneri serotype 4a and their lac+ recombinants from a cross with e. coli hfrc were carried out. considerable differentiation of agglutination reaction was found both in original material and in recombinants. an interesting group included recombinants which completely lost their capability to agglutinate with sera specific for type and group antigens and preserved only the capability to agglutinate in the polyvalent serum of s. ... | 1975 | 1090112 |
| comparison of secretory and histological effects of shigella and cholera enterotoxins in rabbit jejunum. | the purpose of this study was to compare the actions of shigella toxin and cholera toxin to determine if mucosal damage is a prerequisite for shigella toxin-induced secretion. the secretory response to maximal doses of cholera toxin and shigella toxin were compared. the maximal rate of secretion and the electrolyte and protein concentration of the intestinal fluid were similar for both toxins. on the other hand, the time of onset after exposure to the toxin was 105 min for shigella toxin and 15 ... | 1975 | 1090481 |
| occurrence of the bacteriophage lambda receptor in some enterobacteriaceae. | in escherichia coli k-12, the receptor for phage lambda is an outer membrane protein which inactivates the phage in vitro. lambda receptor activity was found in extracts from all wild strains of e. coli tested, although most of them fail to support growth of the phage. in some cases this failure is due to a masking of the receptor in vivo, the bacteria being unable to adsorb the phage or to react with antireceptor antibodies. in other cases, adsorption does occur, and the nature of the block in ... | 1975 | 1090748 |
| shiga bacillus dysentery associated with marked leukocytosis and erythrocyte fragmentation. | granulocytic leukemoid reactions (white blood cell counts greater than 50,000 with myelocytes and promyelocytes in the peripheral blood) were documented in 15 per cent of 273 patients with dysentery due to shigella dysenteriae, type 1 (shiga bacillus) in bangladesh. peak granulocytosis occurred during the second week of illness, when the children were commonly afebrile and diarrhea had ceased or was subsiding. more than half of the patients with leukemoid reactions subsequently developed a fall ... | 1975 | 1090770 |
| production and characterization of exotoxin(s) of shigella dysenteriae type 1. | a semicontinuous fermenter system was developed in which broth culture filtrates of shigella dysenteriae type 1 yielded substantial amounts of exotoxin. biologic activity of the exotoxin was characterized by means of three assays: the rabbit ileal loop for fluid evocation (enterotoxicity), mouse lethality after parenteral injection (neurotoxicity), and hela cell toxicity in vitro (cytotoxicity). although the culture filtrate was highly active, disc electrophoresis revealed that the toxin is a mi ... | 1975 | 1092769 |
| superiority of macconkey's agar over salmonella-shigella agar for isolation of shigella dysenteriae type 1. | the efficiency of macconkey's agar in the isolation of various types of shigella was compared with that of salmonella-shigella (ss) agar during an extensive 18-month outbreak of disease caused by shigella. in all, 1,580 isolates of shigella were obtained from 12,307 rectal swab and fecal samples of patients with diarrhea and their contacts by direct plating onto macconkey's and ss agars. shigella dysenteriae type 1 and shigella flexneri constituted 55 percent and 33 percent of all isolates, resp ... | 1975 | 1094073 |
| letter: hemolytic uremic syndrome after shigellosis. | 1975 | 1094293 | |
| proceedings: dissociation of bacterial pyrexia from prostaglandin e activity. | 1975 | 1097014 | |
| selective cleavage of glycosidic linkages: studies with the o-specific polysaccharide from shigella dysenteriae type 3. | treatment of the o-specific polysaccharide from shigella dysenteriae type 3 with hydrazine in the presence of hydrazine sulphate resulted in quantitative n-deacetylation with the formation of a modified polysaccharide containing free amino groups. oxidation of the modified polysaccharide with periodate did not destroy the 2-amino-2-deoxygalactose residues, thus indicating that they were substituted at position 3. acid hydrolysis of the modified polysaccharide afforded 3-o-(2-amino-2-deoxy-beta ... | 1975 | 1097111 |
| shigella strains associated with infantile diarrhea in the kaohsiung area. | in 1969 and 1974, 375 shigella strains were isolated in the kaohsiung area, and their serotypes and in vitro susceptibility to antimicorbial agents were studied. in 1969, 249 (16.2%) strains were isolated from 1,476 specimens collected from infantile and young children dirrheal cases, whereas 126 strains (11.6%) were isolated from 1,086 specimens in 1969. the isolation rates were higher in may (21.2%), october (20.8%), april (20.6%), august (19.7), november (18.8%) and january (18.5%), than in o ... | 1975 | 1097211 |
| [antigenic relationships between "levinea amalonatica" and "shigella dysenteriae" and "boydii" (author's transl)]. | twenty-eight strains among thirty-five levinea amalonatica show o antigenic relationships with shigella as follows: with s. dysenteriae 3 (5 strains), s. dysenteriae 4 (1 strain), s. dysenteriae 5 (3 strains), s. dysenteriae 7 (11 strains), s. boydii 6 (7 strains), and with both s. boydii 15 and s. dysenteriae 8 (1 strain). these strains do not induce purulent keratogenous conjunctivitis in guinea pigs as shigella do. | 1975 | 1098541 |
| an outbreak of dysentery caused by shigella dysenteriae type 1 on a coral island in the bay of bengal. | an epidemic of severe dysentery occurred on st. martin island in the bay of bengal at a time when the island, with a population of 1,318, was isolated from the mainland because of the monsoon season. there were 434 cases and 28 deaths within a three-month period. mortality (2%) was limited to the very young and the elderly. shigella dysenteriae type 1 (shiga bacillus) was isolated from 12 of 65 rectal swab specimens. all strains gave similar biochemical reactions and were resistant to tetracycli ... | 1975 | 1099145 |
| epidemiologic investigation of an outbreak of shiga bacillus dysentery in an island population. | an epidemic of dysentery broke out in st. martin island during may through july 1973. the epidemic was caused by shigella dysenteriae type 1. the dysentery could not be controlled by conventional antibiotics and other antidysenteric drugs. the average attack rate was 32.9%. the age specific attack rate was highest in the age group 1-4 years (52.2%). the attack rates were higher in smaller families. the rates were not greatly different amongst people using different sources of water. the overall ... | 1975 | 1101385 |
| some immunochemical and chemical aspects of s and r shigella dysenteriae 1 endotoxins. | endotoxins of s and r forms of shigella dysenteriae 1 were prepared by nacl-na citrate extraction, purified by gel chromatography on sephadex g 200 and on sepharose 4b and subjected to immunochemical and chemical analysis. the toxins contained 25--30% of lipids, 40--50% of carbohydrates and 14--24% of protein. the lipid and protein moieties of the lipopolysaccharide-protein complexes exhibited no significant difference, whereas the sugar moieties differed markedly (both qualitatively and quantit ... | 1975 | 1102598 |
| superinfection immunity and prophage repression in phage p1. ii. mapping of the immunity-difference and ampicillin-resistance loci of p1 and phi amp. | 1975 | 1103441 | |
| selective cleavage of glycosidic linkages: studies with the polysaccharide component of shigella dysenteriae type 6 lipopolysaccharide. | the polysaccharide component obtained from the lipopolysaccharide of shigella dysenteriae type 6 was subjected to milk hydrolysis with acid, and the products were fractionated on sephadex g-50. an acidic hexosaminoglycan and a core oligosaccharide fraction were obtained, the former containing d-glucose, d-galactose, 2-acetamido-2-deoxy-d-galactose (in the ratios 1:1:1), and an unidentified acidic component (x). the hexosaminoglycan was n-deacetylated and then hydrolysed and deaminated to give 3- ... | 1975 | 1104165 |
| [pathogenicity factors of gramnegative enteropathogenic bacteria and pathogenesis of intestinal diseases (author's transl)]. | enterotoxins as produced by the majority of enteropathogenic bacteria play a central role in the pathogenesis of cholera and e. coli enteritis but are obviously of little significance as to the development of salmonella enteritis and dysentery. pathology of salmonella enteritis and dysentery results from multiplication of bacteria within the bowel wall and from the damage of tissue caused thereby. the lipopolysaccharides (endotoxins) of invasive enteropathogenic bacteria do not possess the chara ... | 1975 | 1106437 |
| pathogenesis of shigella diarrhea. serum anticytotoxin antibody response produced by toxigenic and nontoxigenic shigella dysenteriae 1. | the serum antitoxin response to the cytotoxin contained in preparations of shigella dysenteriae 1 (shiga's bacillus) exotoxin was studied in natural and experimental infections of man. natural infection resulted in the rapid appearance of toxin-neutralizing antibody, which disappeared some time between 9 and 18 mo after infection. experimental infection of human volunteers provided the opportunity to study immunoglobulin class of the antibody in sera obtained serially from 7 to 50 days after inf ... | 1976 | 1107354 |
| cell-wall lipopolysaccharide of the 'shigella-like' escherichia coli 0124. structure of the polysaccharide chain. | from escherichia coli 0124 two lipopolysaccharide preparations were obtained with phenol/water extraction and cetavlon precipitation. polyacrylamide gel electrophoresis in the presence of sodium dodecylsulfate and chemical analysis showed that the two preparations from e. coli 0124 and the corresponding preparations from shigella dysenteriae type 3 reacted alike. the o-specific polysaccharide moiety was characterized with proton magnetic resonance spectroscopy, optical rotation and paper electro ... | 1976 | 819266 |
| inhibition of adp-induced platelet aggregation as a possible test for evaluation of the enterotoxigenicity of some enterobacteria. preliminary study]. | some culture filtrates or enterotoxin preparations from enterobacteria that activate the adenylate cyclase system (vibrio cholerae, lt fraction from escherichia coli and klebsiella pneumoniae, shigella dysenteriae type 1) exibit an inhibiting effect on adp-induced platelet aggregation, while other enterotoxin preparations not effective on adenylate cyclase system, don't interfere with this model. the a. propose the platelet aggregation as cellular assay to detect enterotoxin fractions effective ... | 1976 | 1028645 |
| studies on shigella isolated in southern taiwan. | during 1969, a total of 1,476 fecal and rectal swab specimens was collected from children with diarrhea and 249 strains of shigella were isolated. the incidence was 16.9%. the serotypes of 249 strains were: shigella dysenteriae, 1.6% (4 strains); s. flexneri, 73.1% (182 strains); s. boydii, 3.2 (8 strains) and s. sonnei, 22.1% (55 strains). there was no marked difference of the isolation rate throughout the whole year. the susceptibility of shigella isolates to chemotherapeutic agents were also ... | 1976 | 1036983 |
| presence of messenger specifying sequences in the dna of chromatin subunits. | messenger-specifying sequences in subunits of human lymphocyte chromatin were detected by hybridization of dna complementary to cytoplasmic polyadenylylated rna with dna isolated from the subunits. comparison of the kinetics and extents of hybridization of complementary dna with chromatin subunit dna and with nuclear dna showed that most of the repetitive sequences and single copy sequences in mrna are present in chromatin subunits. this result indicates that inclusion of a dna sequence into the ... | 1976 | 1064026 |
| the effector cells in human peripheral blood mediating mitogen-induced cellular cytotoxicity and antibody-dependent cellular cytotoxicity. | the identity of the effector cells in human peripheral blood capable of mediating mitogen-induced cellular cytotoxicity (micc) and antibody-dependent cellular cytotoxicity (adcc) was investigated utilizing effector cell populations consisting of purified polymorphonuclear leukocytes, macrophages, lymphocytes, and cell surface immunoglobulin (sig)-negative and sig-positive lymphocyte subpopulations obtained by sephadex anti-fab immunoabsorbent column fractionation techniques. chicken erythrocytes ... | 1976 | 1087314 |
| [diagnostic problems in gout in a 44-year-old man]. | 1976 | 1251615 | |
| radioimmunoassays for free and conjugated trienbolone and for trienbolone acetate in bovine tissue and plasma samples. | a specific, sensitive, precise and accurate radioimmunoassay has been developed for the quantitation of the synthetic anabolic steroid trienbolone acetate (tba) and its major metabolites, free and conjugated trienbolone (tboh) in bovine tissues and plasma. with the extraction procedure described unspecific interference with the antigen-antibody reaction could be ruled out. the assay can significantly detect amounts of more than 40 pg tboh and 70 pg tba. 0.1 - 2.0 g tissue and 0.1 - 1 ml plasma a ... | 1976 | 1273899 |
| naturally occurring sites within the shigella dysenteriae tryptophan operon severely limit tryptophan biosynthesis. | we investigated the structural, functional, and regulatory properties of the shigella dysenteriae tryptophan (trp.) operon in transduction hybrids in which the cysb-trp-region of escherichia coli is replaced by the corresponding region from s. dysenteriae. tryptophan biosynthesis was largely blocked in the hybrids, although the order of the structural genes was identical with that of e. coli. nutritional tests and enzyme assays revealed that the hybrids produced a defective anthranilate synthet ... | 1976 | 770449 |
| tryptophan operon regulation in interspecific hybrids of enteric bacteria. | we examined tryptophan regulation in merodiploid hybrids in which a plasmid carrying the trp operon of escherichia was introduced into trp mutants of other enteric genera, or in which a plasmid carrying the trpr+ (repressor) gene of e. coli was transfered into fully constitutive trpr mutants of other genera. in these hybrids the trp operon of one species is controlled by the repressor of a different species. similar investigations were possible in transduction hybrids in which either the trp ope ... | 1976 | 770450 |
| resistance of shigella dysenteriae type 1 to ampicillin and other antimicrobial agents: strains isolated during a dysentery outbreak in a hospital in mexico city. | in june 1972, an epidemic of dysentery began in a hospital ward lodging 22 children with tuberculosis. fifteen of them developed the disease and five children died. the age of the children ranged from five months to four years. a rectal swab culture taken from all hospitalized children three weeks after the initiation of the outbreak revealed shigella dysenteriae type 1 in five of the patients (28%). the strains isolated were susceptible to cephalothin, gentamicin, kanamycin, colistin, trimethop ... | 1976 | 772132 |
| toxigenic escherichia coli and childhood diarrhea. | stool specimens were examined from 40 children with diarrhea who were under three years of age to determine the incidence of enterotoxigenic escherichia coli in endemic diarrhea. heat-labile e. coli enterotoxin was assayed in the very sensitive and reproducible cultured adrenal tumor cell system. toxigenic e. coli were isolated from only one stool specimen and in this case infection with shigella dysenteriae was also present. none of the eight classic enteropathogenic e. coli isolates were posit ... | 1976 | 775792 |
| [immunochemical and molecular biological characteristics of dysentery phages]. | molecular organization of dna of six dysentery phages was studied for their classification. the pattern of glucosilation of their dna was determined by an immunochemical method and the test of competitive hybridization established the degree of homology of these dna in relation to t4 phage dna. four of the phages (ddvi, zonne "gorkyi" zonne "czechoslovakia", zonne "poland") were shown to belong to the group of t-even phages by their pattern of dna glucosilation and by their capacity to inhibit ... | 1976 | 779271 |
| a bacteriological study of the intestinal mucosa and luminal fluid of adults with acute diarrhoea. | bacteriological studies of jejunal mucosal biopsy specimens and contents were performed on 22 hospitalized adult patients with acute diarrhoea and 24 control normal subjects. none of the washed homogenates of the mucosal specimens were sterile and only one fluid specimen obtained from a control subject was sterile. a definite enteric pathogen was found in only five of the 22 diarrhoea patients. there was no qualitative difference in the bacterial profile of the jejunal mucosa and contents of the ... | 1976 | 779681 |
| methylated guanine derivative as a minor base in the dna of phage ddvi shigella disenteriae. | 7-methylguanine has been identified in the dna of phage ddvi, which replicates in escherichia coli b cells. the amount of this minor base is 0.27 mol per 100 mol of nucleotides. in the dna of ddvi phage there is no 6-methylaminopurine which is usually a minor component in the dna of e. coli b and phage t2, yet the dna of ddvi phage is readily methylated during incubation in vitro with the b-specific methylase and adenosyl[3h]methionine with the label found only in 6-methylaminopurine. an extract ... | 1976 | 779843 |
| semisynthetic cephalosporins. synthesis and structure-activity relationships of 7-sulfonylacetamido-3-cephem-4-carboxylic acids. | the synthesis and in vitro and in vivo activities of a series of 7-sulfonylacetamido-3-cephem-4-carboxylic acids with acetoxymethyl or heterocyclic thiomethyl substituents at the 3 position are described. lengthening the alkyl chain attached to the sulfonyl group increased gram-positive activity but the effect on gram-negative activity was variable. other structural changes on the 7-acyl side chain resulted in only minor changes in vitro activity. the protective effectiveness in infected mice g ... | 1976 | 781242 |
| [grigor'ev-shiga dysentery and the current trends in its spread]. | 1976 | 782107 | |
| intraventricular antipyretics and bacterial pyrogen fever. | in adult fowls with cannulae chronically implanted into the iiird cerebral ventricle or into the hypothalamus, the effects of various hydrosoluble antipyretics, given intraventricularly, on bacterial pyrogen fever were studied. it has been shown that fever evoked by intrahypothalamic or intraventricular infusion of o somatic antigen of shigella dysenteriae was reduced by intraventricular administration of acetylsalicylate-lysine, indomethacin-methylglucamine or ibuprofen-lysine given during the ... | 1976 | 782392 |
| shigella dysenteriae i: a forgotten cause of pseudomembranous colitis. | 1976 | 784931 | |
| inhibition of in vitro protein synthesis by shigella dysenteriae 1 toxin. | 1976 | 786292 | |
| effect of enterotoxins of vibrio cholerae, escherichia coli, and shigella dysenteriae type 1 on fluid and electrolyte transport in the colon. | experiments were designed to determine whether the enterotoxins of vibrio cholerae, escherichia coli, and shigella dysenteriae type 1 alter the movement of fluid and electrolytes in the rat cecum. net secretion of water and sodium were observed after incubation of 1.67 x10(-5) mug of purified cholera toxin (choleragen)/ml for 18 hr or of 50 mug/ml for 3 hr. the effect of choleragen on cecal transport of water and electrolytes was related to the dose. in addition, choleragen increased cecal mucos ... | 1976 | 787442 |
| the problem of bacterial diarrhoea. | the reported incidence of "pathogenic" bacteria, as judged by serotype, in the stools of children with acute diarrhoea has varied from 4 to 33% over the last twenty years. techniques such as tissue culture provide a means for detecting enterotoxin-producing strains of bacteria, strains which often do not possess "pathogenic" serotypes. "pathogenicity" requires redefinition, and the aetiological importance of bacteria in diarrhoea is probably considerably greater than previous reports have indica ... | 1976 | 791597 |
| [effect of gram-negative bacterial polysaccharides on various immunity reactions and experimental tumors]. | 1976 | 794646 | |
| resistance to antibiotics of shigella strains isolated in somalia. | the resistance to antibiotics of 240 shigella strains isolated in somalia from 1973 to 1976 was studied. many strains, particularly those of shigella dysenteriae type 1, were found to be resistant to more than one drug. in view of their resistance to ampicillin, chloramphenicol, streptomycin, tetracycline, and sulfonamides, it is suggested that polymyxin b or m sulfate - which have proved to be effective in vivo - should be used for the treatment of clinically typical cases of bacillary dysenter ... | 1976 | 799953 |
| [epidemiology of human and animal brucellosis in western africa. the results of six studies in the ivory coast, upper volta, and nigeria]. | brucellosis has a two-fold importance in public health: the transmission of the disease to man by contact with animals or ingestion of raw milk is of direct importance; of indirect importance is the loss of animal protein. the authors have carried out ten epidemiological investigations in different bio-climatic zones of west africa. more than 120 villages were evaluated. in each village, 100 persons were chosen at random and all or part of the animal population was also studied. three tests were ... | 1976 | 177324 |
| evaluation of the antilipolytic action of clomiphene in vitro. | clomiphene (10(-3) - 10(-2) m) in a dose-dependent manner inhibited the lypolytic response of isolated rat epididymal adipose tissue and fat cells to epinephrine, acth, and dibutyryl-cyclic amp. furthermore, it reduced the non-hormonally stimulated activity of a crude preparation of lipase from epididymal adipose tissue. the accumulation of cyclic amp produced by epinephrine in fat cells was not prevented by clomiphene at a concentration causing antilipolytic activity. it is concluded from these ... | 1976 | 177345 |
| pregnancy interrupting effects of some bacterial toxins. | embryotoxic properties of shigella dysenteriae and clostridium perfringens toxins, of e. coli endotoxin, v. cholerase and e. coli enterotoxins were compared in mice. e. coli endotoxin has embryotoxic effects at all stages of pregnancy. e. coli enterotoxin v. cholerae enterotoxin and shigella dysenteriae toxin are most effective mainly at earlier stages of pregnancy. clostridium perfringens toxin has no embryotoxic effect. | 1976 | 178014 |
| activation of intestinal mucosal adenylate cyclase by shigella dysenteriae i enterotoxin. | because the mechanism whereby shigella dysenteriae i enterotoxin induces intestinal secretion is unclear, the effect of this toxin on adenylate cyclase activity in rabbit ileal mucosa was studied under various in vitro and in vivo conditions. activation of adenylate cyclase by shigella enterotoxin was observed only when substrate (atp) concentrations above the km of adenylate cyclase were employed. these concentrations of atp are greater than those required to demonstrate activation of adenylate ... | 1976 | 178569 |
| mechanism of plasma cyclic amp response to hypoglycemia in man. | the effect of insulin-induced hypoglycemia on plasma cyclic amp levels was studied in normal volunteers, adrenalectomized, and sympathectomized subjects. significant increases in plasma glucagon were observed in all groups. normal subjects all had two- to threefold rises in plasma camp while no response was seen in any adrenalectomized or sympathectomized subject. these findings suggest that the mechanism for enhanced plasma camp release during insulin-induced hypoglycemia is catecholamine depen ... | 1976 | 178982 |
| the effect of infectious laryngotracheitis virus on the bursa of fabricius of young chickens. | 1976 | 181407 | |
| [infection of hela cells by herpes virus of horses type 1 in different temperature and dose of the virus (author's transl)]. | 1976 | 183896 | |
| monkeypox and whitepox viruses in west and central africa. | prospects for the eradication of smallpox are now highly encouraging. with the cessation of man-to-man transmission, the question of possible animal reservoirs of smallpox becomes increasingly important. during the period 1970-1975, 20 cases of a smallpox-like disease were detected in smallpox-free areas of tropical rain forest in west and central africa. epidemiological and virological investigations revealed that the disease was caused by an animal poxvirus termed monkeypox virus, a member of ... | 1976 | 186209 |
| cyclic adenosine 3', 5'-monophosphate in cerebrospinal fluid during thermoregulation and fever. | 1. samples of cerebrospinal fluid (c.s.f.) have been taken from the cisterna magna of unanaesthetized cats, whilst rectal temperature was recorded, during exposure of the animals to various ambient temperatures and during fever induced by pyrogen. the concentration of adenosine 3', 5'-monophosphate (cyclic amp) in samples of c.s.f. has been assayed. 2. cats exposed to low ambient temperatures (-2 to +2 degrees c) for 3 h maintained body temperature by both behavioural and autonomic heat gain act ... | 1976 | 190383 |
| [obtaining the beta-globulin fractions from swine and cattle sera and a study of their immunological activity]. | the rivanol precipitation was used to obtain beta-globulin fractions from specific swine sera against edema disease, paratyph and aujeszky's disease as well as from normal ovine and swine sera. agar electrophoresis revealed that the preparations produced contained beta-globulin (86 per cent), gamma-globulin (5 per cent), and alpha2-globulin (9 per cent). the beta-globulin preparations were studied for the presence of antibodies against e. coli, salmonellae, staphylococci, myxovirus parainfluenza ... | 1976 | 176771 |
| the oncogenic potential of some avian adenoviruses causing diseases in chickens. | the oncogenic potentials of three different strains of avian adenoviruses (the tipton strain of the inclusion body hepatitis virus, the dpi-2, and the indiana c viruses) were investigated in newborn hamsters. animal inoculations were via two routes, subcutaneous and intracerebral. all three viruses proved nononcogenic for the hamsters observed over a period of 225 days. however, lesions of hepatitis similar to those of inclusion body hepatitis of chickens were seen in three hamsters inoculated w ... | 1976 | 176986 |
| unrelated animal viruses share receptors. | 1976 | 175292 | |
| [epidemiological study of shigella dysenteriae 1 in 2 communities of the guanacaste province, costa rica, 1975]. | 1976 | 136972 | |
| letter: transfer of ampicillin resistance from shigella dysenteriae type 1 to escherichia coli. | 1976 | 59229 | |
| ultrastructural localization of viral antigens using the unlabeled antibody-enzyme method. | employing the unlabeled antibody enzyme method at the ultrastructural level, a comparison was made between preembedding staining and postembedding staining for the detection of viral antigens. the bacteriophage p1 absorbed to the surface of shigella dysenteriae was used as a model system. preembedding staining resulted in the specific deposition of peroxidase-antiperoxidase (pap) complexes as an electron-dense coating around the viral heads. disadvantages of the preembedding staining method incl ... | 1976 | 57192 |
| kinetic properties of serratia marcescens adenosine 5'-diphosphate glucose pyrophosphorylase. | the regulatory properties of partially purified adenosine 5'-diphosphate-(adp) glucose pyrophosphorylase from two serratia marcescens strains (atcc 274 and atcc 15365) have been studied. slight or negligible activation by fructose-p2, pyridoxal-phosphate, or reduced nicotinamide adenine dinucleotide phosphate (nadph) was observed. these compounds were previously shown to be potent activators of the adpglucose pyrophosphorylases from the enterics, salmonella typhimurium, enterobacter aerogenes, e ... | 1976 | 6432 |
| somatic antigens of shigella. structural investigation on the o-specific polysaccharide chain of shigella dysenteriae type 1 lipopolysaccharide. | the o-specific polysaccharide obtained from the lipopolysaccharide of shigella dysenteriae type 1 (shigella shiga) by mild acid hydrolysis followed by fractionation on sephadex g-50 was found to be identical to that desribed by morgan's group and was composed of l-rhamnose, d-galactose and n-acetyl-d-glycosamine in a ratio 2:1:1. on the basis of methylation analysis data the polysaccharide was proved to be a linear chain of monosaccharide residues in pyranose forms substituted at position 3, exc ... | 1976 | 8314 |
| new sugars from antigenic lipopolysaccharides of bacteria: identification and synthesis of 3-o-(r)-1-carboxyethyl-l-rhamnose, an acidic component of shigella dysenteriae type 5 lipopolysaccharide. | a new acidic sugar, 3-o-(r)-1-carboxyethyl-l-rhamnose (1), has been identified as a constituent of the o-antigenic lipopolysaccharide of sh. dysenteriae type 5. the structure of 1 has been established by physico-chemical methods and by synthesis. alkylation of methyl 2,5-di-o-benzyl-alpha-l-rhamnofuranoside (6) with (s)- or (r)-2-chloropropionic acids, followed by removal of the protecting groups, afforded 3-o-(r)-1-carboxyethyl-l-rhamnose (9) and 3-o-(s)-1-carboxyethyl-l-rhamnose (10), respecti ... | 1976 | 12866 |
| studies on the pathogenesis of enteric infections caused by invasive bacteria. | salmonellae, shigellae and some escherichia coli must invade the intestinal epithelial cell and multiply within the mucosa to cause disease. although the bacterial cell most likely possesses several properties essential to this invasive ability, the nature of the cell envelope complex is at present the only characteristic which has been implicated in this process. while a number of pathophysiological events result from invasion, some of our recent efforts have concerned the site and mechanism of ... | 1976 | 62646 |
| sh. dysenteriae serotypes2,4,8-immunochemistry and phage receptor activity. | among three analyzed serotypes of shigella dysenteriae, namely, the serotypes 2,4 and 8, the serotype 2 proved to be a strong immunogen in rabbits, inducing anti-polysaccharide antibodies as well as antiprotein antibodies in all the animals. in contrast, the serotypes 4 and 8 were weak immunogens and among the rabbits some have synthesized only anti-proteins while others had antibodies against the somatic conjugate. aside from the somatic antigens, large amounts of proteins were isolated from al ... | 1976 | 63197 |
| diagnostic value of indirect hemagglutination in the seroepidemiology of shigella infections. | to evaluate the usefulness of the indirect hemagglutination (iha) test in the epidemiological investigation of shigellosis, single serum specimens were tested from 50 patients with shigella dysenteriae 1 (shiga bacillus) infections, 103 asymptomatic contacts of these cases, 267 adult and 100 student control, and serum specimens collected during two outbreaks caused by s. sonnei and one outbreak due to s. flexneri 6. in patients with s. dysenteriae 1, 74% demonstrated titers of greater than or eq ... | 1976 | 767361 |
| rare type of shigellosis. | 1976 | 765409 | |
| hepatitis b surface antigen and hepatocellular carcinoma in southern africa. | most series in africa show a high percentage of hepatitis b surface antigen in hepatocellular carcinoma. two groups of cases were investigated in this study. the one was derived from the autopsy material at baragwanath hospital from subjects who had lived in soweto, a large black urban town. the second group consisted of male black mineworkers generally originating from rural areas. a combination of the aldehydefuchsin stain and immunoperoxidase technique was used. the two groups showed totally ... | 1976 | 233051 |
| [conditions of the dentition and occlusion in nursery school children at ruda slaska]. | 1976 | 274250 | |
| [retinal artery occlusion: etiology and risk factors apropos of 151 cases]. | a retrospective study covering 151 patients was conducted in order to determine the incidence of risk factors (arterial hypertension, diabetes mellitus, smoking, hyperlipidemia, and cardiovascular disorders) in cases of retinal artery occlusion. occlusion of the central artery was found in 43% of the patients, occlusion of one or several branch arteries in 53%, and cilioretinal artery occlusion in 4%. a monofactorial study of risk factors produced a statistically significant value only for arter ... | 1976 | 2366474 |
| [cholecystectomy or drug litholysis of biliary calculi? surgical viewpoint]. | 1976 | 436639 | |
| [bloch-sulzberger syndrome]. | 1976 | 1130070 | |
| [directions for the manufacture of a master model]. | 1977 | 352019 | |
| the development of pulmonary surgery, with special emphasis on carcinoma and bronchiectasis. | 1977 | 352168 | |
| a reappraisal of the value of carcinoembryonic antigen in the management of patients with various neoplasms. | eight hundred and eight patients with histologically proved malignant disease had carcinoembryonic antigen (cea) estimations performed at the time of tissue diagnosis. an elevated level was found in 384 of 518 patients with gastrointestinal neoplasms (74 per cent) and in 162 of 290 patients with other neoplasms (56 per cent). no correlation was found between cea elevations and tumour differentiation. there was a good correlation between tumour staging and cea levels for patients with colorectal ... | 1977 | 420982 |
| computer tomography, radionuclide imaging and ultrasonography in hepatic mass lesions. | the livers of 86 patients comprising this report were examined by both transmission computerized tomography (ct) and radionuclide scans (ls). fifty-nine of them were also examined by gray-scale ultrasound (us). in a comparative study, the strengths and weaknesses of each modality were evaluated. ct demonstrated 85%. us 82%, and ls 73% of masses involving the liver. because of better resolution and sectioning capabilities, together with stop-motion imaging, ct and us detected smaller and deeper m ... | 1977 | 421442 |
| [evaluation of a differential-diagnostic medium with the preparation "progress" for bacteriological diagnosis of dysentery]. | 1977 | 69763 | |
| haemolytic anaemia in bacillary dysentery. | 1977 | 70682 | |
| imported shiga dysentery. | 1977 | 71589 | |
| investigation of the antigenic composition of the cells and the exotoxin of sh. dysenteriae (shiga) by agar immunoelectrophoresis and polyacrylamide gel disc electrophoresis. | using the method of immunoelectrophoresis in agar, we established the presence of 12 soluble antigens in sh. dysenteriae (shiga). we differentiated among them 3 specific antigens situated in the cathodic region. one of them is the somatic o antigen while the other two are thermolabile surface k antigens of these bacteria. k antigens of grigoryev-shiga bacteria differ from the earlier described k antigens of the newcastle and boyd shigellae in their positive electric charge, in greater lability i ... | 1977 | 75222 |
| liver enzyme adaptation after lithium administration in handled and nonhandled rats. | we have examined the interaction of lithium administration and the infant stimulation procedure of handling on hormonally regulated enzymes of liver. animals handled in infancy show an increased morning corticosterone level in response to lithium feeding and markedly elevated serum glucose during refeeding following a two day fast, when compared to non-handled control animals. lithium alters serum corticosterone both in response to the stress of fasting, and during the diurnal cycle following gl ... | 1977 | 21840 |
| effect of different albumin media on the lipid-mobilizing action of sympathicotropic substances in vitro. | the authors studied the effect of adrenotropic substances on lipolysis in rat epididymal adipose tissue in albumin medium in vitro. on using albumins of different origin (human, bovine), the pd2 values for catecholamines differed by more than one order, in correlation to the type of albumin used. the isopropylnorsynephrine pd2 values did not differ. the addition of ascorbic acid (100 microng/ml) raised the catecholamine pd2 values and completely equalized the pd2 values found in both media. the ... | 1977 | 140390 |
| [toxicological characteristics of thaliblastine[]. | the toxic action of the antiphlogistic drug thaliblastin, containing 93-95 per cent of the alcaloid thalicarpine was investigated. with its single intraperitoneal injection to mice the dl10 of the drug amounts to 273-306 mg/kg, dl50-325-350 mg/kg and dl90-370-402 mg/kg. with its 5-day long administration the respective figures for mice are 102-165, 125-201 and 154-243 mg/kg and for rats--170, 203 and 272 mg/kg. the respective figures for a 20-day long introduction to mice are 155, 185 and 220 mg ... | 1977 | 143373 |
| cardiac hypertrophy and antihypertensive therapy. | biochemical (myocardial dna, rna, and hydroxyproline) and humoral (plasma [pra] and kidney [kra] renin activity) factors were determined in spontaneously hypertensive rats (shr) and normotensive wistar controls (nr) before and following treatment with minoxidil or propranolol. minoxidil (150 mg.litre-1 drinking water) effectively controlled blood pressure (17.3 kpa vs 24.9 kpa [130 mmhg vs 187 mmhg], p less than 0.001) despite marked and sustained increases in both pra and kra ventricular weight ... | 1977 | 145319 |
| effect of neurotensin, substance p and morphine sulfate on the secretion of prolactin and growth hormone in the rat. | neurotensin (nt), substance p (sp) and morphine sulfate (ms) elevate plasma prolactin and growth hormone levels in both normal or estrogen-progesterone pretreated male rats. by contrast, steroid priming is required for trf to exhibit prl-releasing activity. naloxone, an opiate receptor blocker, reverses the stimulatory effect of ms only. diphenhydramine, a histamine antagonist, inhibits the response to nt, sp and ms without affecting the response to trf. these results suggest the involvement of ... | 1977 | 95701 |
| subcellular distribution of steroids in rat adrenocortical tissue after incubation in vitro [proceedings]. | 1977 | 194992 | |
| depletion of replenishment of cellular cyclic adenosine monophosphate in hemorrhagic shock. | hemorrhagic shock in rats was produced by bleeding them to a mean arterial blood pressure of 40 millimeters of mercury, which was maintained for two hours. after sacrifice, small pieces of liver, kidney, muscle and brain were quickly removed and frozen in liquid nitrogen. a protein-free extract of tissues was prepared, and cyclic adenosine monophosphate was measured by the radioimmunoassay procedure. analysis os liver, kidney, muscle and brain showed that there were significant reductions in cyc ... | 1977 | 201041 |
| cell culture propagation of porcine rotavirus (reovirus-like agent). | two isolates of porcine rotavirus (reovirus-like agent) were isolated and passaged in primary procine kidney cell cultures. viral infectivity for cells was monitored by immunofluorescence because viral cytopathic effect was moderate. successful passage of virus in cell culture required that viral suspensions obtained from infected cell cultures be treated with pancreatin prior to inoculation onto cell monolayers. porcine rotavirus passage in cell culture also was accomplished, using trypsin trea ... | 1977 | 201198 |
| differential labelling of alpha and beta-noradrenergic receptors in calf cerebellum membranes with 3h-adrenaline. | 1977 | 201857 | |
| [lipoproteins as serum inhibitors in rubella hemagglutination inhibition test and their elimination (author's transl)]. | lipoproteins of 20 human sera were isolated by flotation centrifugation and tested for inhibitory activity in rubella hi-test. low density lipoproteins (ldl) showed the highest titers with an average of 1:238,0, whereas the others (vldl, hdl) had lower titers (see tab. 2). the greatest reduction of all classes of lipoproteins was achieved with kaolin treatment. heparin-manganous chloride and dextran sulfate-calcium chloride method mainly reduced the ldl (84.4 resp. 78.7%). in a comparative test ... | 1977 | 202112 |
| ocular herpes simplex infection. a clinical evaluation of virus isolation and studies on iodo-deoxyuridine resistance. | fifty-seven patients with ocular herpes simplex (hs) infection were studied for evaluation of existing methods for virus isolation and its application in diagnosis of hs infection. virus was isolated in 90% of 34 cases with keratitis dendritica, when specimens were taken within eight days of onset of symptoms. the same isolation frequency was obtained in 10 cases of palpebral herpes with conjunctivitis. no isolation was possible in 11 cases of keratitis disciformis. laboratory confirmation was o ... | 1977 | 202139 |
| intestinal secretion. | 1977 | 190182 | |
| experimental use of a gastric flap on an omental pedicle to close defects in the trachea, pharynx, or cervical esophagus. | the use of local or regional skin flaps for repairs after head and neck cancer surgery often increases the deformity of the patient. we present a new procedure using a gastric flap on an omental pedicle. it has been successful in dog experiments where we transferred it to the head and neck region, to serve as a substitute for the standard skin flaps. | 1977 | 320615 |
| interaction between rifampicin and trimethoprim in vitro and in experimental infections. | 1977 | 321415 | |
| bacterial toxins as virulence factors: shiga bacillus dysentery viewed as a toxinosis. | 1977 | 321946 | |
| [genetics and biochemistry of the bacterial ribosome]. | 1977 | 322729 | |
| biological properties of shigella flexneri 2a toxin and its serological relationship to shigella dysenteriae 1 toxin. | a toxin extracted from heat-inactivated, alkaline-treated shigella flexneri 2a showed biological properties similar to those of shigella dysenteria 1 toxin. the s, flexneri 2a toxin was lethal to mice, enterotoxic for ileal loops of rabbits, and cytotoxic for hela cells. a serological relationship between s. flexneri 2a and s. dysenteriae 1 toxin was shown with cross neutralization tests. | 1977 | 323142 |
| the pathogenesis of shigella diarrhea. vi. toxin and antitoxin in shigella flexneri and shigella sonnei infections in humans. | two strains of shigella flexneri and one of shigella sonnei were studied for toxin production in vitro. all of the three strains produced a cell-free cytotoxin that showed marked similarity to that produced by shigella dysenteriae 1. each toxin eluted in two distinct peaks on chromatography with sephadex g-150, was destroyed by heating at 90 c for 30 min, and was neutralized by s. dysenteriae 1 antitoxin. patients with infections due to s. flexneri and s. sonnei developed antibody that neutraliz ... | 1977 | 323376 |
| characterization of an r-plasmid associated with ampicillin resistance in shigella dysenteriae type 1 isolated from epidemics. | ampicillin-resistant strains of shigella dysenteriae type 1 isolated in epidemics in mexico, central america, and bangla desh were examined for the presence of plasmid deoxyribonucleic acid (dna) by gel electrophoresis. all strains contained a heterogeneous population of plasmids. transfer experiments to escherichia coli k-12 indicated that the ampicillin resistance determinant (ap(r)) was located on a 5.5-megadalton (mdal) plasmid identical in all shiga strains examined, as judged by dna hybrid ... | 1977 | 324394 |
| inhibition of small-intestinal sugar and amino acid transport by the enterotoxin of shigella dysenteriae i. | the enterotoxin of shigella dysenteriae i produces fluid and electrolyte secretion in the rabbit ileum. these present studies were designed to evaluate nonelectrolyte transport in rabbit ileal mucosa exposed to shigella enterotoxin. both 10 mm galactose and 5 mm l-alanine absorptions were significantly impaired in enterotoxin-exposed ileal mucosa compared with control mucosa. l-alanine influx was not imparied in two other secretory processes: that induced by cholera enterotoxin and hyperosmolari ... | 1977 | 324910 |
| pathogenesis of shigella diarrhea. vii. evidence for a cell membrane toxin receptor involving beta1 leads to 4-linked n-acetyl-d-glucosamine oligomers. | the binding of shigeua dysenteriae 1 cytotoxin to hela cells in culture and to isolated rat liver cell membranes was studied by means of an indirect consumption assay of toxicity from the medium, or by determination of cytotoxicity to the hela cell monolayer. both liver cell membranes and hela cells removed toxicity from the medium during incubation, in contrast to wi-38 and y-1 mouse adrenal tumor cells, both of which neither bound nor were affected by the toxin. uptake of toxin was directly re ... | 1977 | 327017 |
| studies on a new antibiotic--chuangxinmycin. | a new antibiotic, designated chuangxinmycin and produced by a new species of microorganism actinoplanes tsinanensis n. sp., has been isolated in crystalline form. assay methods, fermentation and isolation procedures for the antibiotic are described. uv-ir-, nmr- and mass spectra as well as specific rotation of the antibiotic are given. its molecular formula is c12h11no2s. studies on its chemical structure and total synthesis have been completed. according to its chemical structure, chuangxinmyci ... | 1977 | 327539 |
| complete structure of the repeating unit of the o-specific polysaccharide chain of shigella dysenteriae type 3 lipopolysaccharide. | 1977 | 328145 |