Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [detection of antibodies to helicobacter pylori with the immunoenzyme test and indirect immunofluorescence]. | sera from 56 adult patients were screened for the presence of igg antibodies against helicobacter pylori by enzyme immunoassay and indirect immunofluorescence. in addition, the detection of helicobacter pylori in antral biopsy specimens was attempted by culture and histological methods. colonisation of the antrum mucosa with helicobacter pylori was observed in 39 of the 56 patients. igg antibodies against helicobacter pylori were detected by enzyme immunoassay in 34 of 39 infected patients. thus ... | 1990 | 2233106 |
| a newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia. | we identified a motile, curved, gram-negative bacillus as the cause of persistent fever and bacteremia in two patients with symptomatic human immunodeficiency virus infection. the same organism was subsequently recovered from a bone marrow-transplant recipient with septicemia and from two immunocompetent persons with week-long febrile illnesses. all the patients recovered after antimicrobial therapy. | 1990 | 2233947 |
| [campylobacter pylori infection. results of an investigation of 130 patients]. | after recalling the main data on diagnosis, pathogenesis and treatment of cp infection, the results of a study on 130 patients are presented. | 1990 | 2234480 |
| do non-steroidal anti-inflammatory drugs or smoking predispose to helicobacter pylori infection? | susceptibility to helicobacter pylori infection is a poorly understood phenomenon. this study was undertaken to establish whether either smoking or chronic non-steroidal anti-inflammatory drug (nsaid) consumption might in some way predispose to h. pylori infection and hence lead to peptic ulceration. serological evidence of h. pylori infection was assessed in 100 consecutive subjects receiving nsaids without any evidence of gastrointestinal upset and 100 matched controls. all subjects had a full ... | 1990 | 2235801 |
| epidemiology in peptic ulcer disease. current status and future aspects. | peptic ulcer incidence is declining. a decreased prevalence of smokers together with other factors have contributed to this change. the widespread use of non-steroidal anti-inflammatory drugs (nsaid) has increased the incidence of ulcer in the older population and serious complications, such as perforation and bleeding, have been observed especially in older women. helicobacter pylori infection is virtually always present in duodenal and gastric ulcer and active chronic gastritis, but not prepyl ... | 1990 | 2237275 |
| helicobacter pylori: fact or fiction? | the recent isolation and classification of the spiral gastric bacteria helicobacter pylori has led to an explosion of worldwide research. the data strongly suggest that h. pylori is the causative agent for type-b active chronic gastritis. the role of h. pylori in duodenal ulcer awaits clarification, and, more importantly, potential treatment regimens need clear documentation and further detailed research. the past decade has revealed many intriguing facts about h. pylori infection. if, during th ... | 1990 | 2237277 |
| [the frequency of demonstration of campylobacter pylori]. | in 376 patients who underwent gastroscopy the presence of campylobacter pylori by microscopy, bacterial culture and urea test was studied. additionally, the histological examination of the antral mucosa was performed. the organisms were detected in 47.9% of the biopsy specimens (37.2% in normal endoscopic findings and 70% in duodenal ulcers). dependence on sex was not found and also no significant difference of campylobacter pylori detection in patients younger than 45 years compared with those ... | 1990 | 2238751 |
| elimination of helicobacter pylori under treatment with omeprazole. | biopsies from the stomachs (antrum and corpus) of 201 patients with peptic ulcers or reflux oesophagitis were retrospectively investigated for the effect of treatment with omeprazole on the elimination of helicobacter pylori (hp) and on gastritis. of 64 patients without gastritis two (3.1%) developed gastritis during treatment. among 134 patients with hp gastritis undergoing treatment, 48 (35.8%) experienced no hp elimination, in 41 (30.6%) there was hp elimination from the antrum, but hp persis ... | 1990 | 2238754 |
| [gastritis: immunohistochemical detection of specific and nonspecific immune response to helicobacter pylori]. | granulocyte infiltration was studied in 88 biopsies of antrum mucosa from patients with b-gastritis. evidence of iga-, igg- and igm-antibodies as well as of lysozyme in the mucosa was demonstrated by immunohistochemical methods. helicobacter pylori (hp) is coated by antibodies and a significant correlation between extent of opsonisation and number of plasma cells in the connective tissue of the lamina propria could be stated. thus, the infiltration of plasma cells is a specific immune response a ... | 1990 | 2238761 |
| [peptic ulcer and helicobacter pylori]. | 1990 | 2240930 | |
| seroprevalence of helicobacter pylori in seventh-day adventists and other groups in maryland. lack of association with diet. | to evaluate the possible role of diet in the transmission of helicobacter pylori, we compared h pylori seroprevalence among seventh-day adventists (who are vegetarian and abstain from alcohol, caffeine, and meat; n = 94) and two non-seventh-day adventist control groups (n = 168). with the use of an enzyme-linked immunosorbent assay h pylori antigen prepared in a french pressure cell, we found no difference in seroprevalence among these groups; however, seropositivity strongly correlated with age ... | 1990 | 2241444 |
| [helicobacter pylori, peptic diseases and colloid bismuth]. | 1990 | 2244100 | |
| helicobacter pylori infection and chronic gastritis: clinical, serological, and histologic correlations in children treated with amoxicillin and colloidal bismuth subcitrate. | twenty-three children with helicobacter (campylobacter) pylori-associated chronic gastritis are reported. family history of peptic disease, previous digestive procedures, and nonspecific epigastric pain were the most frequently encountered clinical features. antral nodularity at endoscopy and histologic evidence of follicular gastritis were characteristic morphological aspects. rapid urease tests suggested the diagnosis in 90% of patients. significant increases of serum igg and iga against helic ... | 1990 | 2246711 |
| helicobacter pylori and associated duodenal ulcer. | twenty three children with coexistent duodenal ulcer and helicobacter pylori infection were treated with either two weeks of amoxycillin (25 mg/kg/day) in addition to six weeks of cimetidine, or cimetidine alone. endoscopy with antral and duodenal biopsies for urease test, microaerophilic culture, and histological studies were performed at entry, six weeks, 12 weeks, and at six months. children with persistent h pylori infection at six weeks were given a further two weeks' course of amoxycillin. ... | 1990 | 2248531 |
| helicobacter pylori. | 1990 | 2248546 | |
| helicobacter pylori and gastric carcinoma. serum antibody prevalence in populations with contrasting cancer risks. | this investigation examined the correlation between helicobacter pylori (hp) infection, as reflected in immunoglobulin g serum antibodies, and the risk of gastric cancer. serum samples were obtained from populations with contrasting gastric cancer risks. the highest prevalence of hp infection, 93%, was observed in the adult population at highest gastric cancer risk, the residents of pasto, colombia. in the lower risk colombian city of cali, a 63% overall prevalence rate was found. both children ... | 1990 | 2249197 |
| [correlation between campylobacter pylori and chronic atrophic gastritis]. | the correlation between urease activity of campylobacter pylori and atrophic gastritis was studied. on the basis of fundamental study on the optimal ph of c. pylori urease activity, urease activity of 38 biopsied specimens were measured under ph 5 condition, and compared with the positive ratio of c. pylori. in this study, sensitivity was 86.7%, and specificity was 87.0%, respectively. mean urease activity of c. pylori positive specimens was 3.69 miu/mg protein, and under this condition, c. pylo ... | 1990 | 2250390 |
| [helicobacter pylori]. | ever since 1983 when marshall & warren succeeded in cultivating helicobacter pylori (hp) (previously known as campylobacter pylori) a high incidence thereof has been demonstrated in patients with ulcers and non-ulcerous dyspepsia. helicobacter pylori is easily diagnosed via microscopy, cultivation and serological tests. the bacterium may be treated with antibiotics or the ulcer drug bismuth subcitrate (de-nol). the pathogenetic role of hp is not clear. some studies have shown a lower recurrence ... | 1990 | 2251107 |
| [lymphocytic gastritis]. | lymphocytic gastritis is characterised by an accumulation of lymphocytes in the epithelium of the gastric mucosa. this form accounts for 4.5% of chronic b-gastritis and manifests itself by dyspepsia, anorexia and weight loss. the course is benign, as 12 of 19 patients recovered within 24 to 36 months in haot's studies. macroscopically it appears with nodules, erosions, thickened mucosal folds, or diffuse varioliform pattern. the gastric corpus is preferentially involved. the etiology is unknown. ... | 1990 | 2251461 |
| the who's and when's of therapy for helicobacter pylori. | 1990 | 2252013 | |
| helicobacter pylori infection: a simplified diagnostic approach. | we evaluated the diagnostic accuracy of endoscopic finding of nodular antritis and rapid urease test (rut) in order to simplify the approach to the diagnosis of helicobacter pylori (h. pylori) infection. forty-four consecutive patients (mean age 7.9 yr, range 6-13 yr) referred because of recurrent abdominal pain as the main symptom, were prospectively investigated for the presence of h. pylori. h. pylori positivity or negativity was defined as the concordance of two of the following tests: rut, ... | 1990 | 2252019 |
| helicobacter pylori infection in patients with acquired immune deficiency syndrome. | a controlled study was conducted on patients with human immunodeficiency virus (hiv) infection referred for upper endoscopy to evaluate the prevalence of helicobacter pylori (h. pylori) infection. four different stains and culture for h. pylori were performed on biopsy specimens from the gastric antrum. sixteen (40%) of 40 patients with acquired immune deficiency syndrome (aids) or aids-related complex (arc) were diagnosed to be infected with h. pylori versus 14 (39%) of 36 age-matched control p ... | 1990 | 2252020 |
| helicobacter (campylobacter) pylori: a new twist to an old disease. | 1990 | 2252384 | |
| medical treatment of antral gastrin cell hyperfunction: role of nonantisecretory therapy. | antral g cell hyperfunction (agch) is a rare condition, often associated with severe duodenal ulcer disease poorly responsive to medical therapy. up to now, no studies have been designed to investigate a possible role of medical treatment in the management of this syndrome. in this study we treated 9 agch patients with duodenal ulcer, unhealed with the prolonging standard doses of h2 antagonists (300 mg/day ranitidine or 800 mg/day cimetidine), with a nonantacid therapy, tripotassium dicitrato b ... | 1990 | 2253824 |
| relation of helicobacter pylori to the human gastric mucosa in chronic gastritis of the antrum. | the spatial relations between bacteria and the affected tissues can indicate pathogenic mechanisms. this study was undertaken to define the spatial relation of helicobacter pylori to the human gastric mucosa. antibodies against gastric mucus and ruthenium red were used to stabilise the glycoprotein structure of the mucus and glycocalyces in antral biopsy specimens from eight patients infected with h pylori. the location of organisms and ultrastructural features were assessed using systematic sca ... | 1990 | 2253904 |
| evaluation of 13c-urea breath test in the detection of helicobacter pylori and in monitoring the effect of tripotassium dicitratobismuthate in non-ulcer dyspepsia. | sixty nine patients with non-ulcer dyspepsia have been studied with endoscopy, biopsy, quick urease (clo) test, helicobacter pylori culture, and the 13c-urea breath test before and after treatment with tripotassium dicitratobismuthane (denol) two tablets twice daily for four weeks. symptoms of non-ulcer dyspepsia were recorded using a standard questionnaire. using h pylori culture as the gold standard, the sensitivity of the 13c-urea breath test was 90%, the specificity 98.6%, and the accuracy 9 ... | 1990 | 2253905 |
| paf-acether synthesis by helicobacter pylori. | clinical studies suggest that helicobacter pylori may play a role in the pathogenesis of gastroduodenal ulcers in man but direct evidence of mucosal injury by this microorganism is still lacking. paf-acether (paf) causes a number of disorders including ischaemic bowel necrosis and gastroduodenal ulceration. since paf is produced by escherichia coli, we investigated whether it could be synthesised by h pylori. five h pylori isolates were collected from antral biopsy specimens from patients with g ... | 1990 | 2253906 |
| the efficacy of furazolidone and metronidazole in the treatment of chronic gastritis associated with helicobacter (campylobacter) pylori--a randomized double-blind placebo-controlled clinical trial. | seventy-two patients with helicobacter pylori-associated chronic gastritis were randomized to a 3-week oral treatment with furazolidone 0.1g t.i.d. or metronidazole 0.2g t.i.d. or placebo. endoscopy was performed before and after treatment, and biopsy specimens were taken from the antrum of the stomach for histological examination and culture of helicobacter pylori. disappearance rates of helicobacter pylori in furazolidone, metronidazole and the control groups were 74% (20/27) if considering co ... | 1990 | 2253927 |
| [campylobacter pylori--its role in diseases of the upper digestive tract. the present and future]. | in the paper an outline of modern knowledge is presented on campylobacter pylori (helicobacter pylori) which participates in certain upper digestive tract diseases. the history is described of studies on this organism and modern methods of its identification are discussed. the sites of presence of this microorganism are presented in the upper part of the digestive tract and the diseases of this part of the digestive tract are described which are associated with the presence of campylobacter pylo ... | 1990 | 2256330 |
| histologic characteristics of campylobacter pylori (helicobacter pylori) mediated gastritis. | one hundred-nineteen specimens were reviewed to determine whether or not there were histologic changes specific for campylobacter pylori (cp), (helicobacter pylori) mediated gastritis. hematoxylin and eosin (h&e), brown-hopp, and wright-giemsa stained sections were examined independently by two pathologists for (a) the presence of acute cryptitis, (b) percent and degree of crypt involvement, and (c) spectrum of inflammatory cells within the lamina propriae. the amount of mucus was quantified on ... | 1990 | 2256661 |
| nsaid associated gastritis and helicobacter pylori. | 1990 | 2257005 | |
| inhibition of helicobacter pylori haemagglutination activity by human salivary mucins. | thirty isolates of helicobacter pylori from gastric biopsies agglutinated human erythrocyte suspensions. crude mucin preparations derived from saliva of 20 different donors were examined for their ability to inhibit haemagglutination. all mucin preparations exhibited strong inhibitory activity. removal of sialic residues from mucin preparations by treatment with neuraminidase resulted in a substantial reduction of their inhibitory activity. the mucin preparations had no bactericidal or aggregati ... | 1990 | 2257167 |
| seroepidemiology of helicobacter pylori infection in greece. | helicobacter pylori infection is strongly associated with chronic gastritis and peptic ulceration. as the prevalence of h. pylori infection in southern european populations is not known, a serological survey of 1069 samples from three different age groups in the greek population was carried out with an enzyme-linked immunosorbent assay (elisa) for antibodies to these bacteria. the antigen was an ultracentrifuged supernate of whole cell sonicates of 5 isolates of h. pylori assessed by electrophor ... | 1990 | 2257168 |
| helicobacter pylori in its lair: a role in ulcer recurrence? | 1990 | 2258209 | |
| isolation of helicobacter pylori from dental plaques in healthy volunteers. | the presence of helicobacter pylori (h pylori) was looked for in dental plaques of 40 healthy volunteers by clo test, culture and smear stained with warthin-starry stain. h pylori was found to be present in the dental plaques of all 40 volunteers. the dental plaque is an important reservoir of h pylori. | 1990 | 2258210 |
| prevalence of helicobacter pylori in symptomatic patients undergoing gastrointestinal endoscopy. | 1990 | 2258222 | |
| soluble and cell-associated haemagglutinins of helicobacter (campylobacter) pylori. | some plate-grown strains of helicobacter (campylobacter) pylori that were harvested into phosphate-buffered saline and left for 1 h released soluble haemagglutinins. these caused high-titre agglutination of human and guinea-pig erythrocytes, whereas chicken, sheep and bovine erythrocytes were agglutinated at various titres. six of 10 strains which had been subcultured repeatedly did not possess soluble haemagglutinins. slide agglutination of bacterial suspensions demarcated the strains into two ... | 1990 | 2258915 |
| [detection of campylobacter pylori in patients with peptic ulcer as a criterion of the effectiveness of treatment with ultraviolet laser irradiation]. | 1990 | 2259116 | |
| [the role of campylobacter pylori in lesions of the upper segments of the digestive tract in children]. | 1990 | 2259589 | |
| antigenicity of fractions of helicobacter pylori prepared by fast protein liquid chromatography and urease captured by monoclonal antibodies. | the antigenicity of helicobacter pylori protein fractions separated by fast protein liquid chromatography size exclusion was investigated by eia with sera from patients of well defined helicobacter pylori status. the antigenic material of helicobacter pylori was confined to fractions 8 and 14 to 21. urease containing fractions (14/15) and flagella containing fractions (17/18) were identified. fraction 8 non-specifically bound human immunoglobulin as demonstrated by the binding of helicobacter py ... | 1990 | 2261918 |
| the occurrence and extent of helicobacter pylori colonization and antral and body gastritis profiles in an estonian population sample. | a series of 143 subjects representing an estonian urban population was examined for the occurrence and extent (absent, mild, moderate, severe) of helicobacter pylori colonization in antral and body biopsy specimens (giemsa staining). these data were correlated with the presence and grade of chronic gastritis (normal, mild, moderate, or severe superficial chronic gastritis; mild, moderate, or severe atrophic gastritis) in the antrum and the body. gastritis of any grade was found in the antrum and ... | 1990 | 2263873 |
| helicobacter pylori infection and atrophic gastritis in the elderly. | 1990 | 2264888 | |
| systemic chemotherapy for helicobacter pylori eradication? | 1990 | 2265791 | |
| gastric epithelium in the duodenum: its association with helicobacter pylori and inflammation. | duodenal biopsy specimens from 471 adults and 47 children were examined to determine the prevalence and distribution of gastric epithelium in the duodenal bulb in relation to age, gender, gastroduodenal inflammation, smoking, alcohol and consumption of nonsteroidal anti-inflammatory drugs (nsaid). gastric metaplasia was present in the anterior wall duodenal biopsy specimen in 31%, was significantly less common in patients under 17 than in adults, and was more common in males than females. in six ... | 1990 | 2266184 |
| helicobacter pylori in dyspeptic patients in kuwait. | two hundred and four patients, mainly arabs, attending for upper gastrointestinal endoscopy at the gastroenterology clinic in mubarak al-kabeer hospital, kuwait, were examined for evidence of infection with helicobacter pylori and associated inflammation. biopsy specimens of antrum, body, and duodenum; gastric juice; and antral mucosal brushings were investigated by microbiological, cytological, and histopathological methods. clinical conditions diagnosed at endoscopy included gastritis, gastric ... | 1990 | 2266185 |
| helicobacter pylori infection of gastric mucin cell metaplasia: the duodenum revisited. | the histological material of 158 billroth ii gastrectomy specimens, used for a former study that established a relationship between duodenal ulcers and the presence of gastric metaplastic epithelium in the duodenal bulb, was reinvestigated for the presence of helicobacter pylori. the results show that in all duodenal ulcer patients with gastric mucin cell metaplasia h. pylori colonized the metaplastic epithelium accompanied by an inflammatory response. the intestinal mucosa was always negative f ... | 1990 | 2266461 |
| [comparison of colloidal bismuth subcitrate with ranitidine in healing and relapse of campylobacter pylori-associated duodenal ulcers]. | eighty patients with campylobacter pylori-associated duodenal ulcer disease were randomly allocated to receive colloidal bismuth subcitrate (cbs)tablet 120 mg four times a day or ranitidine 150 mg twice daily in a trial comparing the effects of these drugs in short-term healing and post-healing relapse rates of duodenal ulceration. at 8 weeks 88.1% (37/42) of those on cbs and 92.1% (35/38) of those on ranitidine had ulcers healed. the difference is not significant. after ulcer healing, the cumul ... | 1990 | 2269032 |
| investigation of the structure and localization of the urease of helicobacter pylori using monoclonal antibodies. | the urease of helicobacter pylori (formerly campylobacter pylori) has been partly purified by fast protein liquid chromatography. this material contained 10 nm doughnut-like structures when examined by electron microscopy and comprised three major polypeptides (61 kda, 56 kda and 28 kda). only two of these polypeptides (61 kda and 28 kda) were observed in urease-containing material isolated by preparative non-denatured page. monoclonal antibodies (mabs) were produced which were directed against ... | 1990 | 2269872 |
| biochemical changes induced by campylobacter pylori in the gastric juice. | the biochemical changes induced in the gastric juice by the presence of campylobacter pylori (cp) were followed up in 151 patients with various gastric and duodenal diseases. the diagnosis of cp infection was made by the urease test. in the presence of cp urea decreased in the gastric juice and ammonia increased. the sialic acid, fucose and hexoses, glucide components of the mucus glycoproteins dissolved in the gastric juice, underwent no change in the presence of cp. the hexosamines in the gast ... | 1990 | 2270423 |
| helicobacter pylori: its role in gastric disease. | 1990 | 2272122 | |
| [primary peptic ulcer in infancy and childhood. personal experience]. | we report a retrospective review of primary peptic ulcer peptic disease in 61 children. the follow-up period ranged from 1 month to 6 years. all cases were confirmed by endoscopic examination and related with radiological studies result. the number of ulcer peptic disease detected increased as much as the number of endoscopies were performed annually. in the last 20 patients pinch biopsies from antrum were taken looking for campylobacter pylori, encountering 10 positives. the relation male:femal ... | 1990 | 2275489 |
| [14c-urea breath test to diagnose gastric helicobacter pylori colonization]. | helicobacter pylori (h. pylori), ex-campylobacter pylori, is now considered to be the causative agent of active chronic gastritis in humans and may be diagnosed by histology, gram-stain, culture, urease test or noninvasively by 14c-urea breath test. the aim of this study was to determine the sensitivity, specificity, and reproducibility of the breath test as compared with the microbiological (culture) "gold standard". forty-one subjects were studied. gastroscopy was performed in all participants ... | 1990 | 2276558 |
| [human chronic gastritis associated with non-helicobacter pylori spiral organisms (gastrospirillum hominis). four cases and review of the literature]. | four cases of human active chronic gastritis associated with gastrospirillum hominis, a recently described spiral shaped organism are presented. these 4 cases originated from a series of 1976 consecutive gastric biopsies, i.e. a prevalence of 0.25 percent in our material, are compared with helicobacter pylori prevalence of 45 percent. histopathological findings were chronic active gastritis with mild or no atrophy. electron microscopy showed spiral bacteria with terminal flagellae, identical to ... | 1990 | 2276559 |
| identification of flagellar and associated polypeptides of helicobacter (formerly campylobacter) pylori. | flagella of helicobacter pylori were isolated from intact organisms by shearing and differential centrifugation. treatment of the flagella with the detergent triton x-100 removed the flagellar sheath, which was confirmed by electron microscopy, and the remaining naked flagella were shown by sodium dodecyl sulphate polyacrylamide gel electrophoresis (sds-page) to consist primarily of a single 54 kilodalton (kda) polypeptide. this was confirmed by immunogold labelling and electron microscopy of de ... | 1990 | 2276611 |
| upper gastrointestinal manifestations in rheumatoid arthritis patients: intrinsic or extrinsic pathogenesis? | apart from the complication of gastrointestinal vasculitis it is not known whether the upper gastrointestinal (ugi) tract has any special disease characteristics in rheumatoid arthritis (ra). however, oesophageal motility disorders have been reported in 30% of ra patients. hypergastrinaemia has been found in 23-43% of ra patients, usually in combination with a decreased gastric acid output. another finding suggestive of a decreased secretory state, namely a decreased level of pepsinogen a, was f ... | 1990 | 2277973 |
| plastic bag precautions during testing for helicobacter pylori. | 1990 | 2279674 | |
| serodiagnosis of helicobacter pylori infection in childhood. | sera from 100 children (ages, 6 to 16 years) presenting with upper gastrointestinal symptoms were examined for antibodies to helicobacter pylori by enzyme-linked immunosorbent assay (elisa) based on crude, loosely cell-associated antigens and a partially purified urease antigen preparation. all children underwent endoscopy, and 20 children were shown to have h. pylori infection by histology or direct culture. serum anti-h. pylori immunoglobulin g (igg) levels (crude antigen) were clearly raised ... | 1990 | 2279995 |
| [campylobacter pylori (c. pylori): an occasional finding or a constant pathogenetic factor in peptic and inflammatory gastroduodenal pathology? personal observations]. | the detection of cp in the mucosa of the gastric antrum had led to the supposition of this bacterium's potential pathogenetic role in the onset and continuation of peptic ulcer and/or inflammatory gastroduodenal disease. after reviewing the literature, the authors report the incidence rate of the presence of c.p. in the mucosa of the gastric antrum in 110 symptomatic patients. endoscopic examination revealed a negative diagnosis, or the presence of gastric and/or duodenal ulcer, or aspecific inf ... | 1990 | 2280870 |
| [campylobacter pylori and the reparative processes in peptic ulcer]. | the paper deals with reparative potential of gastric and duodenal mucosa in ulcer in connection with the presence and quantity of campylobacter pylori (cp) which is found practically in all patients not only with duodenal localization of ulcer but with mediogastric and pyloroantral localization as well. no correlation between the cp presence and cp mucosa colonization on the one hand and the type of reparative processes in the mucosa is found. the presence or the absence of cp as well as the deg ... | 1990 | 2281967 |
| [helicobacter (campylobacter) pylori in the etiology and pathogenesis of gastritis and peptic ulcer]. | current information on the role of helicobacter pylori (hp) in the stomach and duodenum pathology is presented. hp is always found in active chronic gastritis and duodenal ulcer. hp damage to gastric superficial epithelium may result in the accelerated proliferation and incomplete differentiation of epithelium, this being a basis of chronic gastritis morphogenesis. factors of aggression such as hcl hypersecretion provoke a stomach metaplasia of the duodenal mucosa. hp damage to such areas combin ... | 1990 | 2281970 |
| [campylobacter pylori in patients with liver cirrhosis of different etiologies]. | the role of campylobacter pylori (cp) in the development of chronic gastritis and ulcero-erosive lesions in 76 patients with liver cirrhosis of various etiology is studied. the incidence of cp bacteriosis in liver cirrhosis was 47.3% and the incidence of cp detection by bacteriological methods was not dependent on the cirrhosis etiology. the incidence of cp detection depended on the chronic gastritis activity and the presence of ulcero-erosive lesions. hypochlorhydria is one of the important fac ... | 1990 | 2281974 |
| [chronic gastroduodenitis in children and campylobacter pylori]. | gastric biopsies from 90 children (from 5- to 15-year-old) with chronic gastroduodenitis were examined for campylobacter pylori (cp) by bacteriological, histological (giemsa stain, argentation by warthin-starry, acridine orange stain) and electron microscopical methods. cp is detected in 81.2% children. the degree of colonization was low or moderate. the increase of occurrence was noted with age and duration of disease. persistence of cp went down with the increase of atrophic change in the gast ... | 1990 | 2281975 |
| [helicobacter pylori and chronic gastritis in the gastric biopsy material in a group of randomly selected adult inhabitants of estonia]. | the occurrence of helicobacter pylori (hp) was examined in 227 subjects randomly selected among the estonian population of town kuressaare. hp was present in 166 subjects (73%). in cases of normal mucosa both in antrum and body hp was lacking. if normal gastric body mucosa was associated with antral gastritis hp was found in both regions. more often the contamination of antral and body mucosa with hp occurred in case of superficial gastritis. in subjects with atrophic gastritis the occurrence of ... | 1990 | 2281981 |
| incidence of campylobacter pylori in a consecutive series of surgical patients referred for endoscopy. | over a 9-month period, 109 consecutive patients referred from general surgical out-patient clinics for endoscopy were studied. the presenting symptoms, endoscopic diagnosis, clinical history and degree of histological gastritis were determined. the presence of the organism campylobacter pylori in oesophageal, antral and duodenal biopsies was detected by a combination of culture, histology and fluorescence microscopy. c. pylori was identified in 49.5% of patients by at least one of the methods de ... | 1990 | 2283607 |
| in vitro selection of resistant helicobacter pylori. | four strains of helicobacter pylori were subjected to an in vitro serial passage technique to compare the propensity of the organisms to develop resistance to seven classes of antibacterial agents. the passages were made on serially doubling concentrations of antibacterial agents incorporated into agar starting at one-half the base-line mic. the frequency of spontaneous resistance was also determined for each strain at four and eight times the mic of each antibacterial agent. strains resistant t ... | 1990 | 2285275 |
| [helicobacter pylori. a new species?]. | 1990 | 2287867 | |
| [monoclonal antibodies for specific immunoperoxidase detection of campylobacter pylori]. | 1990 | 2288657 | |
| [physiologic and pathologic age related changes in the stomach]. | while it would be an exaggeration to claim that the stomach does not age, age-related physiological changes are exceptions rather than the rule. in most patients, chronic gastritis is induced by helicobacter pylori, and autoimmune gastritis is rare. a specific ulcer of old age is unlikely; most ulcers in the elderly are drug-induced, with the nsaids predominating. consideration should be given to the fact that a variety of drugs may damage the mucosa, and also to the problems of drug treatment i ... | 1990 | 2289733 |
| specific cellular immune response in patients with helicobacter pylori infection. | the leukocyte migration inhibition test was performed in 39 patients with helicobacter pylori infection and in 38 patients without such infection. the culture of helicobacter pylori was used as antigen. a highly significant inhibitory effect on leukocyte migration was found in patients with helicobacter pylori infection. the results can be taken as proof of a systemic immune response to helicobacters at the cellular level in patients with helicobacter pylori infection. | 1990 | 2289778 |
| [helicobacter pylori and b-gastritis: nonspecific and specific immune mechanisms]. | 1990 | 2290791 | |
| presence of helicobacter pylori in patients with non-ulcer dyspepsia revealing normal antral histological characteristics. | two hundred consecutive patients suffering from non-ulcer dyspepsia were studied for the presence of helicobacter pylori in antral gastritis and normal antral mucosa, using the combination of culture, modified giemsa stain and a sensitive immunoperoxidase stain as means of detection. h. pylori gastritis was present in 56% of the cases. the bacterium was present in 75% of cases of normal antral mucosa, however, in low numbers. it is concluded that 87% of patients with non-ulcer dyspepsia are h. p ... | 1990 | 2292346 |
| peptic ulcer, noxious stress, and campylobacter pylori. | 1990 | 2293595 | |
| campylobacter pylori colonizing heterotopic gastric tissue in the rectum. | campylobacter pylori specifically attaches to gastric epithelial cells and is the etiologic agent for type b gastritis. the authors report the case of a woman with the rare finding of heterotopic gastric mucosa in the rectum that was colonized with c. pylori. histologic findings of the heterotopic mucosa revealed active chronic gastritis that resolved when c. pylori was eradicated with bismuth subsalicylate and antibiotics. this is the first report of c. pylori in a location distal to the duoden ... | 1990 | 2294694 |
| lymphocytic gastritis in patients with celiac sprue or spruelike intestinal disease. | a distinctive form of gastritis, characterized by lymphocytic infiltration of pit epithelium, has recently been described in association with evidence of campylobacter pylori infection. we have evaluated simultaneous small bowel and gastric biopsies from 22 patients with diarrhea or malabsorption, all of which showed small bowel changes characteristic of sprue or spruelike disease. in 10 of 22 patients, striking lymphocytic gastritis was identified. cases positive for lymphocytic gastritis had a ... | 1990 | 2295386 |
| duodenal ultrastructure in patients with chronic renal failure with a comment on the incidence of campylobacter pylori infection. | this study was aimed at identifying ultrastructural abnormalities that may be present in the duodenum of patients with chronic renal failure who were undergoing hemodialysis and that may have an effect on the normal absorptive function of the duodenum. duodenal biopsy specimens from ten patients and four controls were examined. light microscopy showed gastric metaplasia in eight patients and in none of the controls. the main electron microscopic findings were related to the metaplastic changes, ... | 1990 | 2296800 |
| gastric mucosal prostaglandin synthesis in the presence of campylobacter pylori in patients with gastric ulcers and non-ulcer dyspepsia. | it is unclear how campylobacter pylori (cp) interacts with gastric mucosal prostaglandins (pg). in a double-blind study we measured gastric pg synthesis in 22 patients with benign gastric antral ulcers (gu) and 26 with non-ulcer dyspepsis (nud). cp status was determined by histology and bacteriology: 26 (16 gu plus 10 nud) were cp positive, and 22 (6 gu plus 16 nud) were cp negative. patients with severe gastritis regardless of cp status) had significantly higher pge2 and pgi2 values than those ... | 1990 | 2296963 |
| increased blood leukocytes in patients with campylobacter pylori. | 1990 | 2297198 | |
| natural competence for genetic transformation in campylobacter pylori. | 1990 | 2299221 | |
| the origins of helicobacter (campylobacter) pylori. | 1990 | 2300036 | |
| intrafamilial clustering of helicobacter pylori infection. | colonization of the gastric antrum by helicobacter pylori (formerly campylobacter pylori) has been associated with primary gastritis. we determined the frequency of colonization by h. pylori in gastric-antrum biopsy specimens from 93 children undergoing gastroscopy for the evaluation of upper gastrointestinal symptoms. we also determined h. pylori igg antibody levels by enzyme-linked immunosorbent assay in coded serum samples from these children, family members, and control subjects of comparabl ... | 1990 | 2300088 |
| [antibiotic therapy and campylobacter pylori]. | 1990 | 2302995 | |
| does helicobacter pylori colonize the gastric mucosa of meckel's diverticulum? | helicobacter pylori (formerly, campylobacter pylori) is a highly adapted organism that seems to infect only gastric-type mucosa. in this study, we attempted to determine whether gastric epithelium at a site distant from the stomach, the heterotopic gastric mucosa of meckel's diverticulum, was susceptible to colonization by h. pylori. retrospectively, we examined biopsy specimens from 23 patients who had undergone resection of meckel's diverticulum that contained heterotopic gastric mucosa. as a ... | 1990 | 2304363 |
| characterization of and human serologic response to proteins in helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. | helicobacter pylori infection is strongly associated with histologic gastritis and peptic ulcer disease. broth culture supernatants from a subset of h. pylori strains induce vacuolization in cultured cells, a phenomenon that has been attributed to cytotoxin activity. concentrated culture supernatants from 15 of 28 (53.6%) h. pylori strains tested induced vacuolization in hela cells in titers ranging from 1:10 to 1:180. sodium dodecyl sulfate-polyacrylamide gel electrophoresis and silver staining ... | 1990 | 2307514 |
| [evaluation of agar media for growth of campylobacter pylori]. | the supporting ability for the growth of campylobacter pylori was tested on various agar plates. c. pylori grew on media supplemented with blood, serum or egg-yolk, and it showed good growth on mueller hinton agar with horse blood, and on brain-heart infusion agar with yeast extract and horse blood. the organism grew moderately on mueller hinton agar, but could not grow on the other unsupplemented media. mueller hinton medium may be of use as a proper base of blood agar for growth of c. pylori. ... | 1990 | 2308216 |
| [13c-urea breath test as a non-invasive method for the detection of helicobacter (campylobacter) pylori]. | the 13c-urea breath test was used for diagnosing noninvasively the possible presence of helicobacter (formerly called campylobacter) pylori in 20 patients with dyspepsia (ten men and ten women, mean age 40.2 [24-74] years). h. pylori was cultured from 14 patients, while in six the culture was negative. the proportion of 13c in expired air was measured by isotope mass-spectrometer and expressed as delta (basal value about 20%). a dose of 2.5 mg urea per kg body-weight (bw) was ingested after a st ... | 1990 | 2311511 |
| bacterial adhesion and disease activity in helicobacter associated chronic gastritis. | ultrastructural examination of biopsies showing helicobacter pylori associated chronic gastritis reveals close attachment between gastric surface epithelial cells and the organism. the finding of 'adhesion pedestals', which represents a cellular response to the presence of the organism, is analogous to the response of intestinal cells to enteropathogenic e coli. thus the development of bacterial attachment sites in h pylori associated gastritis might be an indication of pathogenicity. we have th ... | 1990 | 2311970 |
| tightly spiral shaped bacteria in the human stomach: another cause of active chronic gastritis? | tightly spiral shaped gram negative bacteria were seen in the gastric biopsies obtained from two patients undergoing gastroscopy. active chronic gastritis was present in both patients and one patient also had gastric ulceration. attempts to culture the organism by a number of methods were unsuccessful but positive urease results were obtained in both patients. both patients were treated with colloidal bismuth subcitrate. biopsies taken after treatment showed resolution of infection and histologi ... | 1990 | 2311971 |
| helicobacter pylori infection in meckel's diverticula. | 1990 | 2311989 | |
| the role of campylobacter (helicobacter) pylori in disorders of the gastrointestinal tract. | to evaluate the role of campylobacter pylori in different gastrointestinal disorders, serum igg antibodies against c. pylori were determined in dyspeptic patients and in a control group of healthy children and adults. twenty-eight percent of the dyspeptic patients with normal mucosa were seropositive. among the patients with altered mucosa, the seroprevalence increased from duodenitis (48%) to gastritis (89%) and gastric or duodenal ulcer, gastric stump gastritis and carcinoma (100%, for each gr ... | 1990 | 2312173 |
| campylobacter pylori in the upper gastrointestinal tract of patients with hiv-1 infection. | fifty one patients with human immuno-deficiency virus (hiv-1) infection who had been consecutively endoscoped for upper gastrointestinal symptoms were biopsied (stomach or duodenum, or both) and compared with 59 age and sex matched controls for the presence of campylobacter pylori. in 28 (47%) of the control group but in only seven (14%) of the hiv seropositive patients were c pylori seen on histological examination (p less than 0.001, odds ratio 5.6, 95% confidence interval 2.2-14.5). sixteen p ... | 1990 | 2312753 |
| distribution of campylobacter pylori in the upper and lower gastrointestinal tract: a microbiological and histological study. | 1990 | 2312755 | |
| patient-to-patient transmission of campylobacter pylori infection by fiberoptic gastroduodenoscopy and biopsy. | three instances of subclinical reinfection with campylobacter pylori were observed in two successfully treated patients during follow-up of c. pylori gastritis. the reinfections occurred 1 month and 21 months (patient 1) and 32 months (patient 2) after the completion of antibacterial treatment. sequential measurement by elisa of serum igg antibody levels to the microorganism showed a significant increase in two of the three instances of reinfection. patient-to-patient transmission was proved by ... | 1990 | 2313129 |
| campylobacter pylori and reflux oesophagitis. | 1990 | 2316352 | |
| helicobacter pylori in gambian children with chronic diarrhoea and malnutrition. | infection with helicobacter pylori (formerly campylobacter pylori) was studied by measuring antibody titres to h pylori in gambian children. serological evidence of infection was found in 12 of 82 (15%) infants aged less than 20 months; this increased to 62 of 135 (46%) in those aged 40-60 months. positive serology was found in 41 of 77 (53%) infants with chronic diarrhoea and malnutrition (mean age 19 months, range 5-36) compared with 18 of 70 (26%) of age matched healthy controls and nearly a ... | 1990 | 2317065 |
| possible evidence of invasiveness of helicobacter (campylobacter) pylori. | gastric/duodenal biopsy material from 52 patients was examined immunohistochemically for helicobacter (campylobacter) pylori. specimens from 34 of the patients harboured helicobacter pylori along the mucosal surface and 13 of these featured, in addition, immunopositive material within the lamina propria. the remaining 18 biopsies were non-reactive. this observation suggests that helicobacter pylori can penetrate the epithelium and its basement membrane, resulting in the production of specific sy ... | 1990 | 2318218 |
| purification and n-terminal analysis of urease from helicobacter pylori. | urease of helicobacter pylori (formerly campylobacter pylori) is believed to represent a critical virulence determinant for this species. ammonia generated by hydrolysis of urea may protect the acid-sensitive bacterium as it colonizes human gastric mucosa. an h. pylori strain, cultured from a gastric biopsy of a patient with complaints of abdominal pain and a history of peptic ulcer disease, was isolated on selective medium and cultured in mueller-hinton broth supplemented with 4% fetal calf ser ... | 1990 | 2318539 |
| lack of in vitro activity of omeprazole against campylobacter pylori. | 1990 | 2318995 | |
| [the course of benign stomach ulcer; results of a follow-up study]. | a follow-up investigation was conducted in 112 patients in whom a benign gastric ulcer had been found endoscopically between 1978 and 1984. nine patients had been operated upon, mainly in the earlier years. out of 65 patients ultimately selected for the study 38 underwent gastroscopy and 35 could be evaluated. of these 21 (60%) had complaints and another 60% used intermittent or continuous medication because of complaints referred to the stomach. in 15 patients erosions (4) or benign gastric ulc ... | 1990 | 2320168 |
| [the urease rapid test (clo test). attempt at statistical analysis for the evaluation of campylobacter colonization in the gastric antrum]. | clo-tests: a statistical analysis for the evaluation of the presence of campylobacter pylori in antral mucosal biopsies. antral biopsies taken in a sample of 475 endoscopy patients were positive for clo on 21% of 77 controls, compared with 39% of non-ulcer dyspepsia (nud) patients without and 69% with a history of former peptic ulcer. epigastric pain was associated with a positive clo-test more frequently than belching or heart burn. patients with nud of turkish or yugoslavian nationality had a ... | 1990 | 2320813 |
| [ulcer symptoms without demonstration of ulcer: causative therapy with demonstration of helicobacter pylori]. | helicobacter pylori-associated gastritis was found by endoscopy in 15 (= 28%) out of 53 patients presenting gastric pain of ulcer type without macroscopically detectable lesion of the gastric mucosa. following a treatment of four weeks with bismuth subcitrate tablets (2 x 2 tablets daily), in 73% improvement of histological findings and in 87% elimination of bacteria could be attained. thus, this causal therapy had a favourable effect on patient complaints. | 1990 | 2320815 |