Publications

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clinical aspects of lyme disease. 19892794810
lyme disease--the great imitator. 19892794806
triple-phase bone image abnormalities in lyme arthritis.arthritis is a frequent manifestation of lyme disease. limited triple-phase tc-99m mdp bone imaging of the wrists and hands with delayed whole-body images was performed in a patient with lyme arthritis. this demonstrated abnormal joint uptake in the wrists and hands in all three phases, with increased activity seen in other affected joints on delayed whole-body images. these findings are nonspecific and have been previously described in a variety of rheumatologic conditions, but not in lyme dise ...19892509122
lyme disease facial palsy: differentiation from bell's palsy. 19892508822
lyme disease. a review and case report with pedal symptoms. 19892664128
pediatric rehabilitation. 5. joint and connective tissue diseases.this self-directed learning module presents pertinent information about rehabilitation management of specific joint and connective tissue diseases affecting children. this section highlights juvenile rheumatoid arthritis, lyme disease, rheumatic fever, hemophilia, dermatomyositis, polymyositis, systemic lupus erythematosus, and other forms of arthritis. it is a section of the chapter of pediatric rehabilitation for the self-directed medical knowledge program study guide for practitioners and tra ...19892655558
be ready for lyme disease in your own backyard. 19892928693
joint pain in children. when is it serious?diagnosis of the cause of joint pain in children depends on the physician's ability to distinguish benign from more serious joint conditions. benign conditions include trauma, overuse syndromes, hypermobility syndrome, chondromalacia patellae, benign recurrent limb pains, and psychogenic rheumatism. conditions that require further evaluation and ongoing therapy include lyme disease, rheumatic fever, juvenile rheumatoid arthritis, neoplastic disease, various orthopedic conditions, infection, sero ...19892928285
erythema chronicum migrans as the presenting manifestation of juvenile chronic myelocytic leukemia.we describe the case of a 3-year-old boy who presented with typical clinical features of lyme disease, including erythema chronicum migrans and arthritis. over subsequent months, however, the clinical picture evolved into juvenile chronic myelocytic leukemia. to our knowledge, the combination of lyme disease and juvenile chronic myelocytic leukemia has not been described. dermatologic and other relevant clinical findings are presented, and the cause and effect relationship between these two rare ...19892731438
surveillance for lyme disease in alabama.to estimate the frequency of occurrence of lyme disease in alabama, in september 1988 the department of public health requested physicians and laboratories to begin voluntary reporting of cases of lyme disease. thirteen cases, 5 confirmed, 1 probable, 4 presumptive and 3 possible, were reported for the years 1986-1988. counties in which tick exposure likely occurred included calhoun, cleburne, mobile, monroe, shelby, talladega and tallapoosa. lyme disease occurs in alabama but appears to be unco ...19892729028
[lyme disease in the child]. 19892665685
lyme disease: a review and an outlook for indiana. 19892656848
[lyme disease. recurrence of the skin lesion after treatment]. 19892716391
[meningo-radiculitis in lyme disease resistant to penicillin g]. 19892523059
eosinophilic lymphadenitis in lyme disease. 19892710589
lyme disease. 19892661449
lyme carditis: an important cause of reversible heart block.lyme disease is a tick-borne spirochetal infection, characterized by erythema chronicum migrans and an acute systemic illness. the disease is endemic in many parts of the north-eastern united states. without treatment, late rheumatic, neurologic, and cardiac complications frequently occur. we report four serologically confirmed cases of lyme carditis in previously healthy young men (mean age, 45 years) from endemic areas. each presented with severe symptomatic atrioventricular block, three with ...19892644885
lyme disease. 19902316437
iritis and papillitis as a primary presentation of lyme disease.a 9-year-old boy had iridocyclitis and papillitis. laboratory evaluation revealed a positive lyme titer. institution of therapy with intravenous ceftriaxone resulted in regression of the ocular inflammation. ophthalmologists should consider lyme disease in the differential diagnosis of iridocyclitis in conjunction with papillitis.19902310116
cns lyme disease. 19902296374
lyme disease misdiagnosed as a temporomandibular joint disorder.craniomandibular disorders cause many pleomorphic and seemingly unrelated clinical manifestations that mimic other more serious medical problems and thus can present physicians and dentists with a challenge that invites misdiagnosis and improper treatment planning. conversely, misdiagnosis and ineffective treatment planning are facilitated when serious medical problems manifest a range of signs and symptoms that are clinically similar to temporomandibular joint muscle dysfunction. at times, the ...19902295991
hla and lyme disease. 19902259886
[lyme disease, a new etiology of prolonged fever]. 19902256598
meningovascular form of neuroborreliosis: similarities between neuropathological findings in a case of lyme disease and those occurring in tertiary neurosyphilis.recent observations have delineated the neurological manifestations of lyme disease, but, to our knowledge, no detailed neuropathological study from autopsy cases has been reported. in this report we describe the neuropathological findings in a case of lyme neuroborreliosis. the chronic meningitis, the occlusive meningovascular and secondary parenchymal changes that we found are similar to those occurring in the meningovascular form of neurosyphilis. thus, we suggest that the case described here ...19902251916
[lyme disease and the forms of its manifestation in bulgaria].two cases of serologically proved cardiac form of lyme's disease are presented (for the first time in bulgaria). an a-v block iii degree was found in the first patient and an a-v block i degree in the second patient. the diagnosis is supported by epidemiologic data--endemic region, other patients with lyme's disease, insects bite, season, etc.19902238623
cerebral atrophy in lyme disease. 19902215913
[benign cutaneous lymphocytoma revealing lyme disease]. 19902163518
[optic neuropathy and lyme disease].lyme disease should be included in the differential diagnosis of acquired optic nerve disorders. protean clinical manifestations of lyme disease, diagnostic clues and treatment are reviewed.19902093403
[a case of the ophthalmological manifestation of systemic tick-borne borreliosis (lyme disease) in the acute period of the disease]. 19902092274
[coxitis in lyme disease]. 19902277886
[a case from practice (198). lyme disease]. 19902093222
[lyme disease in la rioja]. 19902090903
lyme disease: epidemiology, diagnosis, and management. 19902276404
serologic findings in lyme disease. 19902240740
lyme disease in new jersey outdoor workers: a statewide survey of seroprevalence and tick exposure.to evaluate the spread of lyme disease in new jersey, we conducted a statewide cross-sectional study of lyme disease seroprevalence in a high-risk occupational group of outdoor employees. of the 689 employees who participated in the study, 39 (5.7 percent) were positive for antibody to b. burgdorferi, the causative agent of lyme disease. seroprevalence varied markedly by county; unexpectedly high seroprevalence rates were found in several northern counties (sussex, hudson, and hunterdon). furthe ...19902400034
arthralgia: a diagnostic strategy.for arthritis or arthralgia there is no simple system for diagnostic analysis, but whether it is polyarthritis or monoarthritis, acute or chronic in onset, some general rules apply. common causes include osteoarthritis (primary and secondary) and viral infection. drugs should be considered, including those inducing gout. it is still imperative not to miss rheumatic fever, sepsis and tuberculosis in assessment. we may encounter more cases of lyme disease presenting as arthritis.19902248564
[rheumatological manifestations of lyme disease in switzerland]. 19902244097
bone scan abnormalities in a child with lyme disease. 19902225679
lyme disease presenting with bilateral facial nerve palsy.facial palsy bilateral, or recurrent, suggests a myriad of diagnostic possibilities. an 11-year-old boy is described whose diagnosis remained elusive for several months. clinical evolution and subsequent laboratory studies confirmed that he had lyme disease. literature review suggests that this disorder is ubiquitous in its manifestations. the diagnosis should be remembered in unexplained neurologic disorders, particularly in cranial and peripheral neuropathies.19902403282
lyme disease in chronic renal failure: capd therapy. 19902396860
lyme disease presenting as hepatitis and jaundice in a child. 19902235178
lyme disease. 19902217960
lyme neuroborreliosis. peripheral nervous system manifestations.an ever increasing number of apparently unrelated peripheral nervous system (pns) disorders has been associated with lyme borreliosis. to ascertain their relative frequency and significance, we studied prospectively 74 consecutive patients with late lyme disease, with and without pns symptoms: 53% had intermittent limb paraesthesiae, 25% the carpal tunnel syndrome, 8% painful radiculopathy, and 3% bell's palsy; 39% had disseminated neurophysiological abnormalities. to assess the interrelationshi ...19902168778
lyme disease: a seasonal hazard.cutaneous markers are usually the first signs of lyme disease, a multisystem infection that affected about 7,000 people last year. this article reviews its clinical features, diagnosis, and treatment.19902144434
lyme disease in manitoba? 19902208345
lyme disease in canada. 19902208343
orbital myositis with lyme disease. 19902368834
lyme disease. 19902398790
lyme disease in new jersey.lyme disease is a spirochetal infection endemic throughout new jersey. case reports from 1984 through 1986 suggest different high-risk groups and different disease severity than had been observed in earlier cases in the state. both sexes now appear equally at risk, while younger age groups, particularly children less than ten years old, appear to be at increased risk. mild disease is usual, although classic rheumatologic and neurologic complications can occur. informal surveys suggest lyme disea ...19902385371
psychological impact of media coverage of lyme disease. 19902385370
lyme disease: prevention and control. 19902385369
neurological manifestations of lyme disease. 19902200982
lyme disease during pregnancy. 19902200981
clinical manifestations of lyme disease. 19902200980
lyme disease transmitted by a biting fly. 19902342543
neuro-ophthalmologic manifestations of lyme disease.lyme disease is a tick-borne spirochetal infection characterized by skin rash, neurologic, cardiac, and arthritic findings. the authors report six patients with lyme disease who had neuro-ophthalmologic manifestations. one patient had meningitis with papilledema, two had optic neuritis, and one had neuroretinitis. three patients had sixth nerve paresis, two of whom cleared quickly, whereas multiple cranial nerve palsies and subsequent optic neuropathy developed in another. early recognition of n ...19902374674
urticarial vasculitis and lyme disease. 19902370339
lyme disease may underlie bell's palsy. 19902356037
the summer scourge of lyme disease. 19902346183
lyme disease and uveitis. 19902344119
lyme disease presenting as urinary retention.we report a case of lyme disease that presented with urinary retention. the individual then experienced lower extremity paralysis. paralysis and urinary retention resolved with intravenous ceftriaxone antibiotic. to our knowledge this is the first report of a urological manifestation as the initial clinical presentation of lyme disease. recognition of clinical symptoms and urological complications of lyme disease also are discussed.19902342186
ocular lyme disease: case report and review of the literature.lyme disease is an emerging new spirochaetal disease in which ocular complications may arise. we have seen a 45-year-old woman who developed unilateral endophthalmitis leading to blindness during the course of this disease. ocular tissue showed the characteristic spirochete. a literature review shows that the commonest ocular manifestation of lyme disease is a mild conjunctivitis, but other symptoms may include periorbital oedema, oculomotor palsies, uveitis, papilloedema, papillitis, interstiti ...19902198927
lyme disease. 19902198926
lyme disease. 199027433826
lyme disease. 199027433822
lyme disease in alabama. 19902375275
a report on michigan's new lyme disease reporting requirement. 19902359368
how can i avoid lyme disease? what to say to the patient who asks.no magic bullet for eliminating or medical breakthrough for preventing lyme disease can be seen on the horizon. this fast-growing pandemic, second only to acquired immunodeficiency syndrome in public interest and concern, will probably continue to increase in range and incidence for the foreseeable future. ticks are notoriously difficult to thwart, but intelligent application of control measures may be effective. more important, commonsense safety measures offer personal protection to the degree ...19902336417
lyme disease acquired in southeast africa. 19902334195
the enlarging clinical spectrum of lyme disease: lyme cerebral vasculitis, a new disease entity.the case of a patient with cerebral vasculitis with a right thalamic infarct associated with cerebral spinal fluid lyme disease is presented. this entity has not been described in the united states, and only one similar case in the world literature could be found. the patient presented with a progressive headache and subsequent development of grand mal seizure activity. lyme disease has been associated with cranial nerve palsies, peripheral and cranial radiculopathies, aseptic meningitis, enceph ...19902331105
[heart involvement in lyme borreliosis. case report].lyme disease is a systemic illness with skin, neurologic, joint, and cardiac involvement. absence of typical skin lesion--erythema chronicum migrans--during the first period of disease may cause the diagnosis difficult. syncope due to complete atrioventricular block was the first symptom of disease in our patient, but no tick bite anamnestic data were available. quick changes on ekg tracing during cardiac pacing were present. echocardiography revealed left ventricular dysfunction. specific immun ...19902249293
lyme disease. recognizing its many manifestations.lyme borreliosis is a relatively new disease, so much remains to be learned about it. in this article, typical manifestations at each stage are reviewed. however, as the authors emphasize, diagnosis is still a challenge because a given patient may have from a few to all of the features discussed, stages often overlap, and characteristics come and go and may mimic other illnesses.19902186395
biopsy-confirmed cns lyme disease: mr appearance at 1.5 t. 19902112311
lyme disease of the cns: mr imaging findings in 14 cases.the mr images of 14 patients with clinical diagnoses of lyme disease, cns complaints, and positive lyme titers were reviewed. mr examinations were abnormal in 43%. areas of abnormal signal were identified within the cerebral white matter as well as within the brainstem.19902112310
should we try malariotherapy for lyme disease? 19902325716
ear, nose and throat manifestations of lyme disease.the manifestations of lyme disease as they may present to the ent surgeon are discussed. the most important ent symptom is facial palsy. particularly when combined with other cranial palsies, systemic illness or signs of meningeal irritation, the diagnosis must be considered. three case reports are used to illustrate the presentation and diagnosis and treatment of lyme disease. the characteristics of the disease are reviewed and the limitations of serological testing outlined. the literature has ...19902370450
bell's palsy and lyme disease. 19902360945
the season for lyme disease: should ohio physicians be concerned? 19902325988
lyme disease. 19902115360
clinical judgment in lyme disease. 19902108178
[natural foci of lyme borreliosis].the submitted paper provides evidence that tick-borne borreliosis described as lyme disease, is a disease with natural focality. its properties, despite the widespread occurrence, classify it in this group. the authors give a characteristic of the disease, of hitherto known vectors, the main reservoir animals in america and europe. attention is drawn to the importance of deer and the effect of their increasing numbers on the spread of ticks and the disease. the great adaptability of the causal a ...19902142627
lyme disease--united states, 1987 and 1988. 19902317879
lyme disease: first indigenous case in quebec. 19902317878
[lyme disease in the province of sevilla]. 19902329860
lyme disease. 19902340013
[telephone consultation on lyme disease]. 19902304596
fatal lyme carditis and endodermal heterotopia of the atrioventricular node.a fatal case of lyme carditis occurring in a suffolk farmworker is reported. post-mortem examination of the heart showed pericarditis, focal myocarditis and prominent endocardial and interstitial fibrosis. the additional finding of endodermal heterotopia ('mesothelioma') of the atrioventricular node raises the possibility that this could also be related to lyme infection and account for the relatively frequent occurrence of atrioventricular block in this condition. lyme disease should always be ...19902349186
the prevalence of lyme disease in an endemic region. 19902306301
lyme carditis. severe conduction disorder.lyme disease in most cases occurs in the states of connecticut, wisconsin, oregon, california, missouri and parts of the northeastern coast. showing the exception to the rule, the authors discuss a case in which a patient acquired the disease on the eastern shore of virginia.19902304446
lyme polyradiculoneuropathy presenting as increasing abdominal girth.we describe a patient with documented lyme disease whose major complaint was increasing abdominal distention. electrophysiologic studies demonstrated denervation of the lower thoracic paraspinal muscles and the rectus abdominis. expanding abdominal girth can be an unusual manifestation of the polyradiculoneuropathy associated with lyme disease.19902137205
orbital myositis with lyme disease.we examined, treated, and followed up for nine years a 5-year-old girl with active lyme disease and orbital myositis. clinically, the patient demonstrated typical symptoms for each of the major stages of lyme disease, including fever, erythema chronicum migrans, aseptic meningitis, bell's palsy, and arthritis. she subsequently developed clinical and computed tomographic evidence of orbital myositis. although orbital myositis is generally considered to be an idiopathic inflammation, our findings ...19902297027
[telephone consultation about lyme disease]. 19902296315
lyme disease--1988. 19902386663
an immunological study of lyme disease.84 patients in the second or third stages of serologically diagnosed lyme disease suffering from different forms of central as well as peripheral nervous system involvement were tested for the participation of autoimmune mechanisms. cell hypersensitivity to the encephalitogenic basic protein and to antigens from peripheral myelin was evaluated on an opton cytopherometer according to the effect of the macrophage slowing factor--liberated during short-term incubation of sensibilized lymphocytes by ...19901700949
acute reversible diffuse conduction system disease due to lyme disease.during the acute phase of lyme disease, a 56-year-old man without previous heart disease developed complete heart block with alternating left and right bundle branch block pattern qrs complexes. electrophysiological study performed in the acute phase revealed marked hv prolongation, although the level of heart block was at the atrioventricular node. the heart block was mildly symptomatic and resolved (as did the bundle branch block) with antibiotic therapy. lyme disease may cause reversible his- ...19901701888
sequestration of antibody to borrelia burgdorferi in immune complexes in seronegative lyme disease.to find out whether apparent seronegativity in patients strongly suspected of having lyme disease can be due to sequestration of antibodies in immune complexes, such complexes were isolated and tested for antibody to borrelia burgdorferi. in a blinded analysis the antibody was detected in all 10 seronegative lyme disease patients with erythema chronicum migrans (ecm), in none of 19 patients with other diseases, and in 4 of 12 seronegative patients who probably had lyme disease but had no ecm. th ...19901967770
lack of transmission of borrelia burgdorferi by blood transfusion. 19901968566
detection of borrelia burgdorferi infection in ixodes dammini ticks with the polymerase chain reaction.the polymerase chain reaction (pcr) was used to amplify dna sequences of the etiologic agent of lyme disease, borrelia burgdorferi, and was applied to the detection of the spirochete in its tick vector. the target for pcr amplification was the osp-a gene of strain b31; analysis of isolates from different geographical areas indicated that this gene could be used to identify most north american isolates. these methods were extended to the analysis of colony-derived and field-collected ixodes dammi ...19901969867
antibodies to borrelia burgdorferi in guillain-barré syndrome. 19901971906
borrelia burgdorferi elisa titres in children with recent mumps meningitis. 19901975314
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