Publications

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alternative prey use affects helminth parasite infections in grey wolves.predators affect prey populations not only through direct predation, but also by acting as definitive hosts for their parasites and completing parasite life cycles. understanding the affects of parasitism on prey population dynamics requires knowing how their predators' parasite community is affected by diet and prey availability. ungulates, such as moose (alces americanus) and white-tailed deer (odocoileus virginianus), are often important prey for wolves (canis lupus), but wolves also consume ...201627155132
association between gnb3 c.825c > t polymorphism and the risk of overweight and obesity: a meta-analysis.the association between g protein β-polypeptide 3 gene (gnb3) c.825c > t polymorphism (rs5443) and the risk of overweight/obesity has been investigated in many published studies, but the results were conflicting and inconclusive. a meta-analysis was performed to make a more accurate assessment of the relationship.201627114919
risk of symptomatic intracerebral hemorrhage after intravenous thrombolysis in patients with acute ischemic stroke and high cerebral microbleed burden: a meta-analysis.cerebral microbleeds (cmbs) have been established as an independent predictor of cerebral bleeding. there are contradictory data regarding the potential association of cmb burden with the risk of symptomatic intracerebral hemorrhage (sich) in patients with acute ischemic stroke (ais) treated with intravenous thrombolysis (ivt).201627088650
does predation influence the seasonal and diel timing of moose calving in central ontario, canada?birth synchrony is well documented among ungulates and is hypothesised to maximize neonate survival, either by minimizing the risk of predation through predator swamping or by synchronising birthing with increased seasonal food availability. we used encapsulated vaginal implant transmitters to locate and capture neonatal moose calves and document the seasonal and diel timing of parturition in two adjacent study areas with different predation pressure in central ontario, canada. we tested the hyp ...201627082234
summer time predation on the obligatory off-host stage of an invasive ectoparasite.predation can regulate populations and strongly affect invasion success of novel prey. the deer ked (lipoptena cervi; linnaeus 1758) is an invasive ectoparasite of cervids that spends a long period of its life cycle outside the host. prior to this study, virtually nothing was known about natural summer time predation on the deer ked. we aimed to evaluate the magnitude of summer time predation on l. cervi pupae in different habitats and to identify potential predators. we conducted a set of field ...201627707426
a systematic review of iranian experiences in seismo-nephrology.crush syndrome and its potentially life-threatening complications, such as acute kidney injury (aki), are one of the most important medical problems of disaster victims. however, today, many unanswered questions abound about the potential risk factors of crush syndrome, predictive factors of aki, proper amount of prophylactic hydration therapy, type of fluid, time of continuing fluid, intravenous versus oral hydration, etc. therefore, this study was designed to review the findings on iranian nep ...201627703959
moose antler sign, a sign of deep endometriosis infiltrating bowel. 201627693682
arterial aneurysms associated with arteriovenous malformations of the brain: classification, incidence, risk of hemorrhage, and treatment-a systematic review.aneurysms associated with brain arteriovenous malformations (bavms) influence the natural history of these lesions and pose important therapeutic challenges. however, the epidemiology, natural history, and appropriate management of the aneurysms associated with bavms are not completely understood due to the paucity of large and uniform studies. we performed a systematic review of published series examining the association between aneurysms and bavms with the purpose of clarifying the prevalence, ...201627644700
prognostic significance of low microrna-218 expression in patients with different types of cancer: evidence from published studies.mounting evidence showed that micrornas may be useful as prognostic biomarkers of cancer. therefore, we summarize the predictive role of microrna-218 (mir-218) for survival in patients with various cancers.201627631228
the incidence of breast cancer among female flight attendants: an updated meta-analysis.several studies have indicated an increased risk of breast cancer (bc) among female flight attendants (ffas); however, the results from epidemiological studies were not consistent. we thus conducted an updated meta-analysis to re-assess the risk of bc among ffas, according to the moose guideline.201627601531
association between epilepsy and systemic autoimmune diseases: a meta-analysis.to investigate the association between systemic autoimmune diseases (sad) and epilepsy and to determine whether the strength of this association is increased in the young.201627592469
probiotic supplementation in children with cystic fibrosis-a systematic review.probiotics may benefit in cystic fibrosis (cf) as gut dysbiosis is associated with gastrointestinal symptoms and exacerbation of respiratory symptoms in cf. we conducted a systematic review of randomized controlled trials (rcts) and non-rcts of probiotic supplementation in children with cf, using the cochrane methodology, preferred reporting items for systematic reviews (prisma) statement, and meta-analysis of observational studies in epidemiology (moose) guidelines. primary outcomes were pulmon ...201627576473
what effect does transition have on health and well-being in young people with intellectual disabilities? a systematic review.transition to adulthood might be a risk period for poor health in people with intellectual disabilities. however, the present authors could find no synthesis of evidence on health and well-being outcomes during transition in this population. this review aimed to answer this question.201627554952
case fatality of adult tetanus in africa: systematic review and meta-analysis.tetanus is a continued public health neuroinfectious burden in africa; it accounts for significant proportion of lengthy intensive care unit (icu) and hospital admissions.201627538652
publication bias and nonreporting found in majority of systematic reviews and meta-analyses in anesthesiology journals.systematic reviews and meta-analyses are used by clinicians to derive treatment guidelines and make resource allocation decisions in anesthesiology. one cause for concern with such reviews is the possibility that results from unpublished trials are not represented in the review findings or data synthesis. this problem, known as publication bias, results when studies reporting statistically nonsignificant findings are left unpublished and, therefore, not included in meta-analyses when estimating ...201627537925
significantly higher peripheral fibroblast growth factor-2 levels in patients with major depressive disorder: a preliminary meta-analysis under moose guidelines.in vivo and in vitro studies demonstrate the important roles of fibroblast growth factor (fgf) and fgf receptors (fgfrs) in neural survival, neurogenesis, oxidative stress, and emotional behavior. however, evidence on the role of fgf and fgfr in the pathophysiology of major depressive disorder (mdd) remains limited and inconclusive.201627537581
reproductive behaviors and risk of developing breast cancer according to tumor subtype: a systematic review and meta-analysis of epidemiological studies.breast cancer is composed of distinct subtypes defined mainly based on the expression of hormone receptors (hr) and her2. for years, reproductive factors were shown to impact breast cancer risk but it is unclear whether this differs according to tumor subtype. in this meta-analysis we evaluated the association between parity, age at first birth, breastfeeding and the risk of developing breast cancer according to tumor subtype.201627529149
association between mesothelin expression and survival outcomes in patients with triple-negative breast cancer: a protocol for a systematic review.mesothelin is a membrane-bound glycoprotein. although the biologic function of mesothelin is not very clear, researchers have found that it plays a role in the survival, proliferation, and migration of tumor cells. identified as a tumor-associated biomarker, mesothelin is more often overexpressed in triple-negative breast cancer (tnbc) than in common luminal breast tumor subtype or normal tissues. the objective of this review is to determine the association between the expression of mesothelin a ...201627514374
postglacial viability and colonization in north america's ice-free corridor.during the last glacial maximum, continental ice sheets isolated beringia (northeast siberia and northwest north america) from unglaciated north america. by around 15 to 14 thousand calibrated radiocarbon years before present (cal. kyr bp), glacial retreat opened an approximately 1,500-km-long corridor between the ice sheets. it remains unclear when plants and animals colonized this corridor and it became biologically viable for human migration. we obtained radiocarbon dates, pollen, macrofossil ...201627509852
fatty acid composition of birds and game hunted by the eastern james bay cree people of québec.indigenous peoples have traditionally relied on foods hunted and gathered from their immediate environment. the eastern james bay cree people consume wild game and birds, and these are believed to provide health as well as cultural benefits.201627495903
physical activity and alzheimer disease: a protective association.to explore whether being physically active can decrease alzheimer disease (ad) risk.201627492909
migraine and breast cancer risk: a meta-analysis of observational studies based on moose compliant.it has long been speculated that migraine may contribute to an increased risk of breast cancer; however, results from previous studies have been inconclusive. to definitively interrogate this issue, we performed a meta-analysis to assess the correlation between these 2 diseases.medline and pubmed were searched to identify relevant studies that had been published until october 2015. based on a random effects model, relative risk (rr) and the corresponding 95% confidence interval (ci) were used to ...201627472675
substrate-driven convergence of the microbial community in lignocellulose-amended enrichments of gut microflora from the canadian beaver (castor canadensis) and north american moose (alces americanus).strategic enrichment of microcosms derived from wood foragers can facilitate the discovery of key microbes that produce enzymes for the bioconversion of plant fiber (i.e., lignocellulose) into valuable chemicals and energy. in this study, lignocellulose-degrading microorganisms from the digestive systems of canadian beaver (castor canadensis) and north american moose (alces americanus) were enriched under methanogenic conditions for over 3 years using various wood-derived substrates, including ( ...201627446004
efficacy and safety of endoscopic third ventriculostomy and choroid plexus cauterization for infantile hydrocephalus: a systematic review and meta-analysis.endoscopic third ventriculostomy/choroid plexus cauterization (etv/cpc) has gained popularity in its treatment of infantile hydrocephalus over the past decade. in this manuscript, we perform a systematic review and meta-analysis to determine the efficacy and safety of etv/cpc, and to compare the procedural outcomes between north american and sub-saharan african cohorts.201627613635
moose on the loose: checklist for meta-analyses of observational studies. 201627790686
cha2ds2-vasc risk factors as predictors of stroke after acute coronary syndrome: a systematic review and meta-analysis.stroke is a rare but serious complication of acute coronary syndrome. at present, no specific score exists to identify patients at higher risk. the aim of the present study is to test whether each clinical variable included in the cha2ds2-vasc score retains its predictive value in patients with recent acute coronary syndrome, irrespective of atrial fibrillation.201627708110
biomonitoring of selected persistent organic pollutants (pcdd/fs, pcbs and pbdes) in finnish and russian terrestrial and aquatic animal species.the finnish and russian animal species (semi-domesticated reindeer, finnish wild moose, baltic grey seal and baltic herring) samples were biomonitored in terrestrial and aquatic environments for polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdd/fs), polychlorinated biphenyls (pcbs) and polybrominated diphenylethers (pbdes).201627752440
prevalence of placenta previa among deliveries in mainland china: a prisma-compliant systematic review and meta-analysis.placenta previa is characterized by the abnormal placenta overlying the endocervical os, and it is known as one of the most feared adverse maternal and fetal-neonatal complications in obstetrics.201627749592
prognostic significance of neutrophil-to-lymphocyte ratio in colorectal liver metastasis: a systematic review and meta-analysis.inflammation is deemed to play critical roles in tumor progression and metastasis, and an increased neutrophil-lymphocyte ratio (nlr) has been reported to correlate with poor survivals in various malignancies. however, association between nlr elevation and survival outcome in patients with colorectal liver metastasis (crlm) remains controversial. the aim of this study was to investigate the prognostic significance of elevated nlr in crlm.201627427969
ungulate browsers promote herbaceous layer diversity in logged temperate forests.ungulates are leading drivers of plant communities worldwide, with impacts linked to animal density, disturbance and vegetation structure, and site productivity. many ecosystems have more than one ungulate species; however, few studies have specifically examined the combined effects of two or more species on plant communities. we examined the extent to which two ungulate browsers (moose [alces americanus]) and white-tailed deer [odocoileus virginianus]) have additive (compounding) or compensator ...201627386099
guidelines for reporting medical research: a critical appraisal.as a response to a low quality of reporting of medical research, guidelines for several different types of study design have been developed to secure accurate reporting and transparency for reviewers and readers from the scientific community. herein, we review and discuss the six most widely accepted and used guidelines: prisma, consort, strobe, moose, stard, and spirit. it is concluded that the implementation of these guidelines has led to only a moderate improvement in the quality of the repor ...201627382637
therapeutic approach to igg4-related disease: a systematic review.to review the reported evidence on the therapeutic management of igg4-related disease (igg4-rd) in clinical practice.a systematic search of the literature was conducted. the primary outcome measured was the rate of efficacy of first-line therapeutic approaches. secondary outcomes measured included the rate of disease relapse, the outcome of untreated patients, the rate of patients without drug therapy at the end of follow-up, the rate of side effects, and mortality. the moose, ahrq, strobe, and ...201627368010
xrcc1 and ogg1 gene polymorphisms and breast cancer: a systematic review of literature.known polymorphisms of dna repair genes can be associated with the risk of many types of cancer. there is no consensus regarding association between xrcc1 and ogg1 with breast cancer (bc).201627366307
large herbivores surf waves of green-up during spring.the green wave hypothesis (gwh) states that migrating animals should track or 'surf' high-quality forage at the leading edge of spring green-up. to index such high-quality forage, recent work proposed the instantaneous rate of green-up (irg), i.e. rate of change in the normalized difference vegetation index over time. despite this important advancement, no study has tested the assumption that herbivores select habitat patches at peak irg. we evaluated this assumption using step selection functio ...201627335416
prognostic role of mucin antigen muc4 for cholangiocarcinoma: a meta-analysis.surgery carries the best hope for cure in the treatment of cholangiocarcinoma (cc), whereas surgical outcome is not fully satisfactory. bio-molecular markers have been used to improve tumor staging and prognosis prediction. mucin antigen muc4 (muc4) has been implicated as a marker for poor survival in various tumors. however, prognostic significance of muc4 for patients with cc remains undefined. the aim of the present meta-analysis was to investigate the association between muc4 expression and ...201627305093
effect of exercise training on sleep apnea: a systematic review and meta-analysis.obstructive sleep apnea (osa) is difficult to manage for those who are intolerant or noncompliant with standard facial mask treatment options. current treatment options do not address the underlying cause of osa. exercise as a treatment option has been found to improve osa indices.201627296826
cadmium and other elements in tissues from four ungulate species from the mackenzie mountain region of the northwest territories, canada.tissue samples from four ungulate species from the south mackenzie mountain region of the northwest territories (nt), canada, were analysed for stable and radioactive elements and (15)n and (13)c stable isotopes. elevated cd concentrations in moose (alces americanus) kidney have been observed in the region and are a health care concern for consumers of traditional foods. this study examined the factors associated with, and potential renal effects from, the accumulation of cadmium, and interactio ...201627240258
diabetes mellitus as a risk factor for surgery-related pressure ulcers: a meta-analysis.the purpose of this study was to determine whether diabetes mellitus is associated with increased likelihood of surgery-related (perioperative) pressure ulcers.201622864191
an integrated review of developmental outcomes and late-preterm birth.to evaluate existing evidence on long-term developmental outcomes of late-preterm infants (lpi; infants born 34-36 6/7 weeks gestation).201621771069
defense behavior of moose. 201617278844
comment on dissociation between running economy and running performance in elite kenyan distance runners.mooses and colleagues suggest that running economy alone does not explain superior distance running performance in elite kenyan runners. whilst we agree with the multi-factorial hypothesis for kenyan running success, we do not believe that running economy can be overlooked to the extent that it was based on this particular study. based on the methods used and the range of athletes tested, in this response letter we question whether this study provides any basis for downplaying the influence of r ...201625352492
[the simulation of 137cs distribution in forest ecosystems and prediction of its accumulation by forest products].a mathematical model of 137cs migration in forest ecosystem is presented, which describes the behaviour of this radionuclide in the forest litter-soil system, trees, understory and forest animals. the model's parameters for different types of forest ecosystems are estimated and model's adequacy is tested through the use of independent experimental data. the sensitivity of the model's output variables is analyzed to variations in the most significant parameters. the differences in the seasonal an ...201611402557
rt-quic assays in humans … and animals.prion diseases are neurodegenerative diseases affecting both humans and animal species. the phenotypic spectrum is broad and includes creutzfeldt-jakob disease (cjd) and its variant zoonotic form (vcjd) in humans, while in animals, scrapie of sheep and goats, bovine spongiform encephalopathy and chronic wasting disease of deer, elk and moose are naturally occurring forms. transmission and pathogenesis appear causally linked to the misfolding of the normal form of the prion protein (prpc) into di ...201632231915
student experience at moose factory. 20164787594
[reduction of plant fibers in the digestive tract of the moose and the red deer].a comparative study of the reduction of plant fibers moving in the digestive tract of nine red deer (cervus elaphus) and six moose (alces alces) was made. in the winter season, the character of fiber reduction in the moose and the red deer was similar. in the deer obtained in the early autumn, the relative concentration of small-sized fractions was significantly higher. a sharp decrease in the share oflarge-sized fibers was observed in the omasum as compared to the rumen and the reticulum. it wa ...201623136740
[the role of the urals in the genetic diversity of the european moose subspecies (alces alces alces)].the genetic diversity of the uralian moose population and the role of the ural region in the phylogeographic structure of the european moose were evaluated based on sequence polymorphisms of the mtdna control region. the nucleotide diversity of the ural moose was low, whereas haplotype diversity was rather high. it was found that the haplotype pool of the ural moose reflects both the unique features of their mitochondrial lineages and their connection with alces alces alces populations of europe ...201625739308
complete mitochondrial genome of a wild amur moose (alces alces cameloides).in this study, the complete mitochondrial genome (mt dna) of amur moose (alces alces cameloides) was sequenced, using muscle tissue obtained from a male amur moose. the total length of the mitochondrial genome is 16,305 bp. the genome structure of amur moose is similar to other moose and it contains 12s rrna gene, 16s rrna gene, 22 trna genes, 13 protein-coding genes, and 1 control region.201625629496
swimming attendance during childhood and development of asthma: meta-analysis.the association between asthma and swimming pool attendance has not been demonstrated and currently there are conflicting results. in order to clarify the association between asthma diagnosis in children and swimming pool attendance, and to assess the consistency of the available epidemiological studies, we completed a literature analysis on the relationship between the exposure to disinfection by-products in indoor swimming pools during childhood and asthma diagnosis.201628032933
rituximab shows no effect on remission in patients with refractory nephrotic syndrome: a moose-compliant meta-analysis.to assess the efficacy of rituximab in treatment of refractory nephrotic syndrome (ns) compared with other agents.studies were searched from web of science, pubmed, and cnki up to april 2016. the standardized mean difference or relative risk or odds ratio and 95% confidence intervals were used to assess the efficacy of rituximab treatment compared with other agents in refractory ns.totally, 8 studies were included. the present study showed that there was a significant higher relapse-free surviva ...201627977574
homocysteine and risk of age-related macular degeneration: a systematic review and meta-analysis.there is still no agreement on total plasma homocysteine (thcy) role in age-related macular degeneration (amd), the leading cause of new blindness in industrialized countries. we performed a systematic review and meta-analysis of the published data on the correlation between thcy and amd. medline/pubmed and isi web of sciences searches were performed according to moose guidelines. case-control studies were eligible for inclusion. participants and controls were amd patients and subjects without a ...201627966830
prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: a systematic review with meta-analysis.aspiration pneumonia is thought to be associated with a poor outcome in patients with community acquired pneumonia (cap). however, there has been no systematic review regarding the impact of aspiration pneumonia on the outcomes in patients with cap. this review was conducted using the moose guidelines: patients: patients defined cap.201627924871
current construct options for revision of large acetabular defects: a systematic review.many treatment options are available for the revision of large acetabular defects. debate continues as to which technique is most effective.201627922983
multiple browsers structure tree recruitment in logged temperate forests.historical extirpations have resulted in depauperate large herbivore assemblages in many northern forests. in eastern north america, most forests are inhabited by a single wild ungulate species, white-tailed deer (odocoileus virginianus), and relationships between deer densities and impacts on forest regeneration are correspondingly well documented. recent recolonizations by moose (alces americanus) in northeastern regions complicate established deer density thresholds and predictions of browsin ...201627893758
do emergency medicine journals promote trial registration and adherence to reporting guidelines? a survey of "instructions for authors".the aim of this study was to evaluate the current state of two publication practices, reporting guidelines requirements and clinical trial registration requirements, by analyzing the "instructions for authors" of emergency medicine journals.201627881175
prognostic value of microrna-9 in various cancers: a meta-analysis.recently, there are more and more evidences from studies have revealed the association between microrna-9 (mir-9) expression and outcome in multiple cancers, but inconsistent results have also been reported. it is necessary to rationalize a meta analysis of all available data to clarify the prognostic role of mir-9. eligible studies were selected through multiple search strategies and the quality was assessed by moose. data was extracted from studies according to the key statistics index. all an ...201627844330
anti-brucella antibodies in moose (alces alces gigas), muskoxen (ovibos moschatus), and plains bison (bison bison bison) in alaska, usa.we used an indirect enzyme-linked immunosorbent assay (ielisa) and the rose bengal test (rbt) to test for anti-brucella antibodies in moose (alces alces gigas), muskoxen (ovibos moschatus), and plains bison (bison bison bison) from various game management units (gmus) in alaska, us, sampled from 1982 to 2010. a portion of the sera had previously been tested with the standard plate test (spt), the buffered brucella antigen (bba) card test, and the card test (card). no antibody-positive plains bis ...201626540335
the first detection of species of babesia starcovici, 1893 in moose, alces alces (linnaeus), in norway.babesiosis is an emerging zoonotic disease and various wildlife species are reservoir hosts for zoonotic species of babesia starcovici, 1893. the objective of the present study was to investigate the presence and prevalence of babesia spp. in moose alces alces (linnaeus) in two regions of norway. a total of 99 spleen samples were collected from animals of various ages from an area with the occurrence of the tick ixodes ricinus (linnaeus, 1758), and from an area where the ticks are known to be ab ...201627188749
anaplasma phagocytophilum infection in moose (alces alces) in norway.anaplasma phagocytophilum is a tick-borne bacterium that infects a wide range of animal species. the aim of our study was to investigate the prevalence of a. phagocytophilum in norwegian moose alces alces and to characterize the bacteria by sequencing of partial msp4 and 16s rrna genes. hunters collected spleen samples from 99 moose of different ages during 2013 and 2014 in two areas: aust-agder county (n = 70) where ixodes ricinus ticks are abundant and oppland county (n = 29) where ticks were ...201626428857
prey selection of scandinavian wolves: single large or several small?research on large predator-prey interactions are often limited to the predators' primary prey, with the potential for prey switching in systems with multiple ungulate species rarely investigated. we evaluated wolf (canis lupus) prey selection at two different spatial scales, i.e., inter- and intra-territorial, using data from 409 ungulate wolf-kills in an expanding wolf population in scandinavia. this expansion includes a change from a one-prey into a two-prey system with variable densities of o ...201628030549
mobility of moose-comparing the effects of wolf predation risk, reproductive status, and seasonality.in a predator-prey system, prey species may adapt to the presence of predators with behavioral changes such as increased vigilance, shifting habitats, or changes in their mobility. in north america, moose (alces alces) have shown behavioral adaptations to presence of predators, but such antipredator behavioral responses have not yet been found in scandinavian moose in response to the recolonization of wolves (canis lupus). we studied travel speed and direction of movement of gps-collared female ...201628035275
markers for ongoing or previous hepatitis e virus infection are as common in wild ungulates as in humans in sweden.hepatitis e virus (hev) is a human pathogen with zoonotic spread, infecting both domestic and wild animals. about 17% of the swedish population is immune to hev, but few cases are reported annually, indicating that most infections are subclinical. however, clinical hepatitis e may also be overlooked. for identified cases, the source of infection is mostly unknown. in order to identify whether hev may be spread from wild game, the prevalence of markers for past and/or ongoing infection was invest ...201627657108
potential role of soil properties in the spread of cwd in western canada.chronic wasting disease (cwd) is a horizontally transmissible prion disease of free ranging deer, elk and moose. recent experimental transmission studies indicate caribou are also susceptible to the disease. cwd is present in southeast alberta and southern saskatchewan. this cwd-endemic region is expanding, threatening manitoba and areas of northern alberta and saskatchewan, home to caribou. soil can serve as a stable reservoir for infectious prion proteins; prions bound to soil particles remain ...201624618673
early and non-invasive detection of chronic wasting disease prions in elk feces by real-time quaking induced conversion.chronic wasting disease (cwd) is a fatal prion disease of wild and captive cervids in north america. prions are infectious agents composed of a misfolded version of a host-encoded protein, termed prpsc. infected cervids excrete and secrete prions, contributing to lateral transmission. geographical distribution is expanding and case numbers in wild cervids are increasing. recently, the first european cases of cwd have been reported in a wild reindeer and two moose from norway. therefore, methods ...201627829062
first case of chronic wasting disease in europe in a norwegian free-ranging reindeer.chronic wasting disease (cwd) is a fatal contagious prion disease in cervids that is enzootic in some areas in north america. the disease has been found in deer, elk and moose in the usa and canada, and in south korea following the importation of infected animals. here we report the first case of cwd in europe, in a norwegian free-ranging reindeer in southern norway. the origin of the disease is unknown. until now a low number of cervids, and among them a few reindeer, have been tested for cwd i ...201627641251
chronic wasting disease drives population decline of white-tailed deer.chronic wasting disease (cwd) is an invariably fatal transmissible spongiform encephalopathy of white-tailed deer, mule deer, elk, and moose. despite a 100% fatality rate, areas of high prevalence, and increasingly expanding geographic endemic areas, little is known about the population-level effects of cwd in deer. to investigate these effects, we tested the null hypothesis that high prevalence cwd did not negatively impact white-tailed deer population sustainability. the specific objectives of ...201627575545
caribou consumption in northern canadian communities.chronic wasting disease (cwd) is a transmissible spongiform encephalopathy (tse) found in both farmed and wild deer, elk, and moose in the united states and canada. surveillance efforts in north america identified the geographical distribution of the disease and mechanisms underlying distribution, although the possibility of transmission to other cervids, including caribou, and noncervids, including humans, is not well understood. because of the documented importance of caribou (rangifer tarandu ...201627556568
dietary magnesium and copper affect survival time and neuroinflammation in chronic wasting disease.chronic wasting disease (cwd), the only known wildlife prion disease, affects deer, elk and moose. the disease is an ongoing and expanding problem in both wild and captive north american cervid populations and is difficult to control in part due to the extreme environmental persistence of prions, which can transmit disease years after initial contamination. the role of exogenous factors in cwd transmission and progression is largely unexplored. in an effort to understand the influence of environ ...201627216881
serological evidence of tick-borne encephalitis virus infection in moose and deer in finland: sentinels for virus circulation.the incidence of tick-borne encephalitis (tbe) in humans has increased in finland, and the disease has emerged in new foci. these foci have been investigated to determine the circulating virus subtype, the tick host species and the ecological parameters, but countrywide epidemiological information on the distribution of tbev has been limited.201626825371
first evidence of established populations of the taiga tick ixodes persulcatus (acari: ixodidae) in sweden.the tick species ixodes ricinus and i. persulcatus are of exceptional medical importance in the western and eastern parts, respectively, of the palaearctic region. in russia and finland the range of i. persulcatus has recently increased. in finland the first records of i. persulcatus are from 2004. the apparent expansion of its range in finland prompted us to investigate if i. persulcatus also occurs in sweden.201627370406
movement is the glue connecting home ranges and habitat selection.animal space use has been studied by focusing either on geographic (e.g. home ranges, species' distribution) or on environmental (e.g. habitat use and selection) space. however, all patterns of space use emerge from individual movements, which are the primary means by which animals change their environment. individuals increase their use of a given area by adjusting two key movement components: the duration of their visit and/or the frequency of revisits. thus, in spatially heterogeneous environ ...201625980987
complete mitochondrial genome sequence of ussurian moose, alces alces cameloides.ussurian moose (alces alces cameloides) in northeast china, which is on the southmost edge of the species' eurasian range, are facing dramatic decline in population size and distribution areas. we undertook the first sequencing of the entire mitogenome of ussurian moose, which is thought as the oldest moose subspecies to better understand the evolutionary history of this circumboreal sole extant species. the mitogenome is 16,418 bp in length, consisting of two ribosomal rna (rrna) genes, 22 tran ...201625962486
rumen microbiota for wild boreal cervids living in the same habitat.knowledge about the factors shaping the rumen microbiota in wild animals is limited. therefore, the aim of this study was to compare the microbiota from the three cervid species moose (alces alces, n = 5), red deer (cervus elaphus, n = 4) and roe deer (capreolus capreolus, n = 12), sharing the same habitat. using deep 16s rrna gene sequencing, we found that the largest species moose had the highest number of unique operational taxonomic units. furthermore, red deer and moose shared more of the m ...201627737946
identification of the pregnancy-associated glycoprotein family (pags) and some aspects of placenta development in the european moose (alces alces l.).this study describes the identification and a broad-based characterization of the pregnancy-associated glycoprotein (pag) genes expressed in the synepitheliochorial placenta of the alces alces (aa; n = 51). we used: (1) both size measurements (cm) of various aa embryos/fetuses (crown-rump length) and placentomes (plcs); (2) pcr, southern and sequencing; (3) western-blot for total placental glycoproteins; (4) deglycosylation of total cotyledonary proteins; and (5) double heterologous ihc for cell ...201627501873
epidemiology of the lymphatic-dwelling filarioid nematode rumenfilaria andersoni in free-ranging moose (alces alces) and other cervids of north america.moose (alces alces) are a culturally and economically valued species in minnesota, where the northeast population has decreased by 60 % since 2006. the cause of the decline is currently unclear; however, parasites, predation, and climate change have all been implicated. nematode parasites are important pathogens in north american moose, potentially causing severe disease and mortality. recent spread of rumenfilaria andersoni, a filarioid nematode of moose, has been documented in finnish cervids; ...201627519789
harvest-induced phenotypic selection in an island population of moose, alces alces.empirical evidence strongly indicates that human exploitation has frequently led to rapid evolutionary changes in wild populations, yet the mechanisms involved are often poorly understood. here, we applied a recently developed demographic framework for analyzing selection to data from a 20-year study of a wild population of moose, alces alces. in this population, a genetic pedigree has been established all the way back to founders. we demonstrate harvest-induced directional selection for delayed ...201627174031
modelling (137)cs concentrations in moose (1986-2012) from areas highly contaminated by the chernobyl fallout.data from long term annual monitoring of (137)cs concentrations in harvested moose (alces alces) were empirically modelled by applying multivariate data analysis that is able to from relatively raw datasets show how the many various impact variables are related (principal component analysis, pca). in the later stage regression modelling (partial least squares, pls) was applied to analyse which environmental and physiological factors were significant (i.e. of predictive value) based on the measur ...201627162195
range expansion of moose in arctic alaska linked to warming and increased shrub habitat.twentieth century warming has increased vegetation productivity and shrub cover across northern tundra and treeline regions, but effects on terrestrial wildlife have not been demonstrated on a comparable scale. during this period, alaskan moose (alces alces gigas) extended their range from the boreal forest into tundra riparian shrub habitat; similar extensions have been observed in canada (a. a. andersoni) and eurasia (a. a. alces). northern moose distribution is thought to be limited by forage ...201627074023
the nutritional balancing act of a large herbivore: an experiment with captive moose (alces alces l).the nutrient balancing hypothesis proposes that, when sufficient food is available, the primary goal of animal diet selection is to obtain a nutritionally balanced diet. this hypothesis can be tested using the geometric framework for nutrition (gf). the gf enables researchers to study patterns of nutrient intake (e.g. macronutrients; protein, carbohydrates, fat), interactions between the different nutrients, and how an animal resolves the potential conflict between over-eating one or more nutrie ...201626986618
geographic distribution and molecular diversity of bartonella spp. infections in moose (alces alces) in finland.moose, alces alces (artiodactyla: cervidae) in finland are heavily infested with deer keds, lipoptena cervi (diptera: hippoboschidae). the deer ked, which carries species of the genus bartonella, has been proposed as a vector for the transmission of bartonellae to animals and humans. previously, bartonella dna was found in deer keds as well as in moose blood collected in finland. we investigated the prevalence and molecular diversity of bartonella spp. infection from blood samples collected from ...201626967131
quantifying migration behaviour using net squared displacement approach: clarifications and caveats.estimating migration parameters of individuals and populations is vital for their conservation and management. studies on animal movements and migration often depend upon location data from tracked animals and it is important that such data are appropriately analyzed for reliable estimates of migration and effective management of moving animals. the net squared displacement (nsd) approach for modelling animal movement is being increasingly used as it can objectively quantify migration characteri ...201626938257
sarcocystosis in wild red deer (cervus elaphus) in patagonia, argentina.sarcocystis spp. are protozoan parasites with a heteroxenous life cycle, which produce cysts in the muscle of herbivorous animals. in these animal species, sarcocystosis is frequently asymptomatic, although it may occur with high prevalence. seven sarcocystis spp. have been described in red deer (cervus elephus). the aim of this study was to determine the prevalence of sarcocystosis, and to perform the morphological and molecular characterization of sarcocystis spp. found in wild red deer of the ...201626779923
mosquitoes in moose country: a mosquito survey of northern minnesota.an adult mosquito survey was conducted at 12 sites using carbon dioxide traps in northern minnesota throughout the summer of 2012. specimens were counted, identified to species, sorted into pools, and tested for eastern equine encephalitis (eeev) and west nile virus (wnv). our findings extend the known range of culiseta melanura, anopheles barberi, and an. quadrimaculatus and document the presence and abundance of 27 other mosquito taxa in the region. none of the pools tested positive for eeev o ...201627280346
bacterial genomics reveal the complex epidemiology of an emerging pathogen in arctic and boreal ungulates.northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at high latitudes. understanding the causes and consequences of shifting pathogen diversity and host-pathogen interactions in these ecosystems is important for wildlife conservation, and for indigenous populations that depend on wildlife. among the key ...201627872617
lungworm (nematoda: protostrongylidae) infection in wild and domestic ruminants from małopolska region of poland.the conducted study has focused on domestic, as well as wild ruminant species. the post mortem examination was carried out on 68 animals, including three wild species: roe deer (capreolus capreolus) (25 indyviduals), red deer (cervus elaphus) (6), fallow deer (dama dama) (5) and two domestic: sheep (ovis aries) (14) and cattle (bos taurus) (18). some of the species have also been investigated in the field by the coproscopical analyses. the faecal samples from roe deer (27), fallow deer (20), red ...201627262959
description and life-cycle of taenia lynciscapreoli sp. n. (cestoda, cyclophyllidea).a new species of tapeworm, taenia lynciscapreoli sp. n. (cestoda, cyclophyllidea), is described from the eurasian lynx (lynx lynx), the main definitive host, and the roe deer (capreolus capreolus and capreolus pygargus), the main intermediate hosts, from finland and russia (siberia and the russian far east). the new species was found once also in the wolf (canis lupus) and the eurasian elk/moose (alces alces), representing accidental definitive and intermediate hosts, respectively. the conspecif ...201627199592
seroprevalence, isolation, first genetic characterization of toxoplasma gondii, and possible congenital transmission in wild moose from minnesota, usa.toxoplasma gondii infections are widespread in white-tailed deer (odocoileus virginianus) but little is known of its prevalence in other cervids in the usa. moose (alces alces) is a popular large game animal, hunted for its meat and trophy antlers. here, we report seroprevalence, isolation, and genetic characterization of t. gondii from moose from minnesota. antibodies against t. gondii were detected in 8 of 79 (10%) moose tested by the modified agglutination test (mat 1:25 or higher). the myoca ...201626472716
morphological and molecular characterization of sarcocystis taeniata and sarcocystis pilosa n. sp. from the sika deer (cervus nippon) in lithuania.the diaphragm muscles of eight sika deer (cervus nippon) bred in lithuania were examined for sarcocystis cysts. two sarcocystis species, sarcocystis taeniata, which were previously reported in canadian moose (alces alces) and argentinean red deer (cervus elaphus), and sarcocystis pilosa n. sp. were described using light microscopy (lm), transmission electron microscopy (tem), 18s ribosomal dna (rdna), and subunit i of cytochrome c oxidase (cox1) sequences analysis. by lm, cysts of s. taeniata we ...201627086872
mitotypical peculiarities of the population of moose alces alces of southeastern west siberia.based on the structure of the d-loop control region of mitochondrial dna, the genetic diversity of moose of west siberia was evaluated and their placement within the structure of current species population was determined. it was noted that the values of genetic diversity exceed the values of analogous indices obtained for western groups of the species. three haplogroups were identified in the population structure: european- ural, west siberian, and american.201630251792
chronic wasting disease (cwd) in cervids.in april and may of 2016, norway confirmed two cases of chronic wasting disease (cwd) in a wild reindeer and a wild moose, respectively. in the light of this emerging issue, the european commission requested efsa to recommend surveillance activities and, if necessary, additional animal health risk-based measures to prevent the introduction of the disease and the spread into/within the eu, specifically estonia, finland, iceland, latvia, lithuania, norway, poland and sweden, and considering seven ...201732625260
transplacental transmission of neospora caninum in moose (alces alces).a 5-years-old moose (alces alces) cow kept in a zoo in the german federal state of brandenburg aborted a female foetus of 44cm crown rump length (crl). pathohistological analysis revealed several neospora (n.) caninum infected cells and cysts, as well as multifocal gliosis, necrosis, haemorrhages, dystrophic mineralisation and haemosiderosis in the brain, predominantly in cerebrum and brainstem. in addition, mild lymphocytic meningitis was present. together with the fresh foetus, a mummified foe ...201731014840
the european union summary report on surveillance for the presence of transmissible spongiform encephalopathies (tse) in 2016.this report presents the results of surveillance activities on transmissible spongiform encephalopathies (tses) in bovine animals, sheep, goats, cervids and other species, as well as genotyping data in sheep, carried out in 2016 in the european union according to regulation (ec) 999/2001, and in iceland, norway and switzerland. in 2016, 1,352,585 bovine animals were tested in the european union (5% less than in 2015). for the first time, the united kingdom did not report any case of bovine spong ...201732625357
birthweight and pcos: systematic review and meta-analysis.are intrauterine conditions, reflected in birthweight, associated with the development of polycystic ovary syndrome (pcos)?201730895228
systematic reviews of prognosis studies: a critical appraisal of five core clinical journals.prognosis research refers to the investigation of association between a baseline health state, patient characteristic and future outcomes. the findings of several prognostic studies can be summarized in systematic reviews (srs), but some characteristics of prognostic studies may result in difficulties when performing the analyses. this study aimed to investigate trends in the volume and quality of srs of prognostic studies in the literature.201731093540
morphological and molecular characterization of four sarcocystis spp., including sarcocystis linearis n. sp., from roe deer (capreolus capreolus) in italy.fresh (frozen/thawed) muscle samples from four 2-12-year-old roe deer (capreolus capreolus) from the sondrio province in north-eastern italy were examined under a dissecting microscope, and about 180 sarcocysts were isolated and identified to morphological type in wet mounts by light microscopy (lm). seventy-seven of these sarcocysts were subsequently examined by molecular methods, comprising polymerase chain reaction (pcr) amplification and sequencing of the partial cytochrome c oxidase subunit ...201728255918
interferon-γ release assays for the diagnosis of mycobacterium tuberculosis infection in children: a literature review.the role of interferon-gamma release assays (igras) for immunologic diagnosis of tuberculosis in children is under debate. we carried out a narrative review on the studies on igras in paediatric populations. a literature search was conducted using multiple keywords and standardized terminology in medline, embase and cochrane databases, up to january 27th, 2011. study quality was assessed using the moose checklist and results of relevant studies were summarized. sixty-seven paediatric studies (st ...201722697065
modelling moose-forest interactions under different predation scenarios at isle royale national park, usa.loss of top predators may contribute to high ungulate population densities and chronic over-browsing of forest ecosystems. however, spatial and temporal variability in the strength of interactions between predators and ungulates occurs over scales that are much shorter than the scales over which forest communities change, making it difficult to characterize trophic cascades in forest ecosystems. we applied the landis-ii forest succession model and a recently developed ungulate browsing extension ...201728263421
detection and molecular characterization of the mosquito-borne filarial nematode setaria tundra in danish roe deer (capreolus capreolus).setaria tundra is a mosquito-borne filarial nematode of cervids in europe. it has recently been associated with an emerging epidemic disease causing severe morbidity and mortality in reindeer and moose in finland. here, we present the first report of s. tundra in six roe deer (capreolus capreolus) collected between october 2010 and march 2014 in denmark. the deer originated from various localities across the country: the eastern part of the jutland peninsular and four locations on the island zea ...201728229043
gross measurements of the digestive tract and visceral organs of addax antelope (addax nasomaculatus) following a concentrate or forage feeding regime.differences in macroscopic measurements of the gastrointestinal tract have been hypothesized to correlate with the browser-grazer continuum in the natural diet of ruminants. however, to what extent these characteristics represent species-specific traits, or respond to the actually ingested diet, remains to be investigated. twelve surplus addax antelope (addax nasomaculatus) were divided into two groups and fed, for 3 months, either their usual diet, consisting of a concentrate feed with a limite ...201728295511
serological testing of schmallenberg virus in swedish wild cervids from 2012 to 2016.schmallenberg virus (sbv) first emerged in europe in 2011, and in sweden in late 2012. the virus was still circulating in parts of europe in 2015. in recent testing, the virus has not been detected in swedish domestic animals, indicating that it is no longer circulating in sweden. it is not known if the virus has circulated and is still circulating in swedish wild cervid populations and whether wildlife can act as virus reservoirs. the aim of this study was to investigate whether sbv has circula ...201728376790
moose-tree interactions: rebrowsing is common across tree species.plant strategies to resist herbivory include tolerance and avoidance. tolerance strategies, such as rapid regrowth which increases the palatability of new shoots, can lead to positive feedback loops between plants and herbivores. an example of such a positive feedback occurs when moose (alces alces) browse trees in boreal forests. we described the degree of change in tree morphology that accumulated over time in response to repeated browsing by moose, using an index of accumulated browsing. we e ...201728376769
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